LOCUS       DAVIME010000001       118798 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVIME010000001 DAVIME010000000
VERSION     DAVIME010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 118798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.001"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            140..427
                     /locus_tag="VV588_000001"
     CDS             140..427
                     /locus_tag="VV588_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082431.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNTLKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLG"
     gene            1037..1729
                     /locus_tag="VV588_000002"
     CDS             1037..1729
                     /locus_tag="VV588_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU7082432.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1782..4193
                     /locus_tag="VV588_000003"
     CDS             1782..4193
                     /locus_tag="VV588_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU7082433.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4443..5144
                     /locus_tag="VV588_000004"
     CDS             4443..5144
                     /locus_tag="VV588_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082434.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5146..7854
                     /locus_tag="VV588_000005"
     CDS             5146..7854
                     /locus_tag="VV588_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU7082435.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGCFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NVFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7950..8441)
                     /gene="tpx"
                     /locus_tag="VV588_000006"
     CDS             complement(7950..8441)
                     /gene="tpx"
                     /locus_tag="VV588_000006"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU7082436.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8564..9493)
                     /gene="psaA"
                     /locus_tag="VV588_000007"
     CDS             complement(8564..9493)
                     /gene="psaA"
                     /locus_tag="VV588_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU7082437.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKATTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9525..10373)
                     /locus_tag="VV588_000008"
     CDS             complement(9525..10373)
                     /locus_tag="VV588_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU7082438.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10370..11092)
                     /locus_tag="VV588_000009"
     CDS             complement(10370..11092)
                     /locus_tag="VV588_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU7082439.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11383..13275
                     /gene="pepO"
                     /locus_tag="VV588_000010"
     CDS             11383..13275
                     /gene="pepO"
                     /locus_tag="VV588_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU7082440.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13398..14027)
                     /locus_tag="VV588_000011"
     CDS             complement(13398..14027)
                     /locus_tag="VV588_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU7082441.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            15023..17245
                     /locus_tag="VV588_000012"
     CDS             15023..17245
                     /locus_tag="VV588_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU7082442.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMDQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17275..17718
                     /locus_tag="VV588_000013"
     CDS             17275..17718
                     /locus_tag="VV588_000013"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU7082443.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGVAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGANMQVELVNNGPVTIILDTKKR"
     gene            complement(17757..18172)
                     /locus_tag="VV588_000014"
                     /pseudo
     CDS             complement(17757..18172)
                     /locus_tag="VV588_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18532..18894
                     /locus_tag="VV588_000015"
     CDS             18532..18894
                     /locus_tag="VV588_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082444.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEEDVLILLSELQNFFLDVFQAKRIHRA
                     FCVRLCLKAQFLLSNNDS"
     gene            19075..19374
                     /locus_tag="VV588_000016"
     CDS             19075..19374
                     /locus_tag="VV588_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082445.1"
                     /translation="MNRDVLEFLRTETAEKISLYISEANRLEGDVTLLAPSSQDLEDI
                     KNAMLSNSNLGLKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(19469..19906)
                     /locus_tag="VV588_000017"
     CDS             complement(19469..19906)
                     /locus_tag="VV588_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082446.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(20008..20673)
                     /locus_tag="VV588_000018"
     CDS             complement(20008..20673)
                     /locus_tag="VV588_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU7082447.1"
                     /translation="MAIASGYLNSRLDKFVDWGPWTALVPFGLISVTNVGISMLSTRF
                     TGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQEGRPN
                     QMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMNLLAYVTTIAFALSLIANALNALK
                     LTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIEGNSN
                     KEY"
     gene            complement(20861..21511)
                     /locus_tag="VV588_000019"
     CDS             complement(20861..21511)
                     /locus_tag="VV588_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU7082448.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            21623..22465
                     /locus_tag="VV588_000020"
     CDS             21623..22465
                     /locus_tag="VV588_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU7082449.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQENFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            22541..22978
                     /locus_tag="VV588_000021"
     CDS             22541..22978
                     /locus_tag="VV588_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU7082450.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            23047..23349
                     /locus_tag="VV588_000022"
     CDS             23047..23349
                     /locus_tag="VV588_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082451.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(23440..24513)
                     /locus_tag="VV588_000023"
     CDS             complement(23440..24513)
                     /locus_tag="VV588_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU7082452.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            24669..25346
                     /locus_tag="VV588_000024"
     CDS             24669..25346
                     /locus_tag="VV588_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7082453.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            25339..26313
                     /locus_tag="VV588_000025"
     CDS             25339..26313
                     /locus_tag="VV588_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU7082454.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLFLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(26362..28305)
                     /gene="thrS"
                     /locus_tag="VV588_000026"
     CDS             complement(26362..28305)
                     /gene="thrS"
                     /locus_tag="VV588_000026"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU7082455.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNIAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVNYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(28363..28686)
                     /locus_tag="VV588_000027"
     CDS             complement(28363..28686)
                     /locus_tag="VV588_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU7082456.1"
                     /translation="MELQELVEHSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            29551..30096
                     /locus_tag="VV588_000028"
     CDS             29551..30096
                     /locus_tag="VV588_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU7082457.1"
                     /translation="MKLAVIAANGQVGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            30322..30591
                     /gene="rpsO"
                     /locus_tag="VV588_000029"
     CDS             30322..30591
                     /gene="rpsO"
                     /locus_tag="VV588_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU7082458.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            31407..32021
                     /locus_tag="VV588_000030"
     CDS             31407..32021
                     /locus_tag="VV588_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU7082459.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(32314..33063)
                     /locus_tag="VV588_000031"
     CDS             complement(32314..33063)
                     /locus_tag="VV588_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU7082460.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMILKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            33196..35532
                     /locus_tag="VV588_000032"
     CDS             33196..35532
                     /locus_tag="VV588_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU7082461.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQAKK"
     gene            35633..36310
                     /locus_tag="VV588_000033"
     CDS             35633..36310
                     /locus_tag="VV588_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU7082462.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSK"
     gene            36297..37094
                     /locus_tag="VV588_000034"
     CDS             36297..37094
                     /locus_tag="VV588_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU7082463.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            37111..38214
                     /locus_tag="VV588_000035"
     CDS             37111..38214
                     /locus_tag="VV588_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU7082464.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWLSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLSILDQAPANELFPGLQGFDNLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            38221..38412
                     /locus_tag="VV588_000036"
     CDS             38221..38412
                     /locus_tag="VV588_000036"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082465.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            38515..39534
                     /gene="galE"
                     /locus_tag="VV588_000037"
     CDS             38515..39534
                     /gene="galE"
                     /locus_tag="VV588_000037"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU7082466.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            39536..40501
                     /locus_tag="VV588_000038"
     CDS             39536..40501
                     /locus_tag="VV588_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU7082467.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(40552..40758)
                     /locus_tag="VV588_000039"
     CDS             complement(40552..40758)
                     /locus_tag="VV588_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU7082468.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            40810..41286
                     /locus_tag="VV588_000040"
     CDS             40810..41286
                     /locus_tag="VV588_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU7082469.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            41295..41966
                     /locus_tag="VV588_000041"
     CDS             41295..41966
                     /locus_tag="VV588_000041"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU7082470.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            42096..42434
                     /locus_tag="VV588_000042"
     CDS             42096..42434
                     /locus_tag="VV588_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU7082471.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIHIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            42437..43066
                     /locus_tag="VV588_000043"
     CDS             42437..43066
                     /locus_tag="VV588_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU7082472.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            43306..44457
                     /locus_tag="VV588_000044"
     CDS             43306..44457
                     /locus_tag="VV588_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU7082473.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGARLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            44775..45524
                     /gene="truA"
                     /locus_tag="VV588_000045"
     CDS             44775..45524
                     /gene="truA"
                     /locus_tag="VV588_000045"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU7082474.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            45514..46287
                     /locus_tag="VV588_000046"
     CDS             45514..46287
                     /locus_tag="VV588_000046"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU7082475.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            46265..46726
                     /locus_tag="VV588_000047"
     CDS             46265..46726
                     /locus_tag="VV588_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU7082476.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            complement(46985..47188)
                     /locus_tag="VV588_000048"
     CDS             complement(46985..47188)
                     /locus_tag="VV588_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7082477.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(47181..48263)
                     /locus_tag="VV588_000049"
     CDS             complement(47181..48263)
                     /locus_tag="VV588_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU7082478.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(48389..49171)
                     /locus_tag="VV588_000050"
     CDS             complement(48389..49171)
                     /locus_tag="VV588_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU7082479.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(49171..50514)
                     /locus_tag="VV588_000051"
     CDS             complement(49171..50514)
                     /locus_tag="VV588_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU7082480.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGTYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(50613..51929)
                     /locus_tag="VV588_000052"
     CDS             complement(50613..51929)
                     /locus_tag="VV588_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU7082481.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDINGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            52122..53348
                     /locus_tag="VV588_000053"
     CDS             52122..53348
                     /locus_tag="VV588_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU7082482.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            53547..55121
                     /locus_tag="VV588_000054"
     CDS             53547..55121
                     /locus_tag="VV588_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU7082483.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            55385..56173
                     /gene="codY"
                     /locus_tag="VV588_000055"
     CDS             55385..56173
                     /gene="codY"
                     /locus_tag="VV588_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU7082484.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            56173..56748
                     /locus_tag="VV588_000056"
     CDS             56173..56748
                     /locus_tag="VV588_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU7082485.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            56830..56915
                     /locus_tag="VV588_000057"
     tRNA            56830..56915
                     /locus_tag="VV588_000057"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56864..56866,aa:Leu,seq:aag)
     gene            57198..58328
                     /gene="ugpC"
                     /locus_tag="VV588_000058"
     CDS             57198..58328
                     /gene="ugpC"
                     /locus_tag="VV588_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU7082486.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            58827..59585
                     /locus_tag="VV588_000059"
     CDS             58827..59585
                     /locus_tag="VV588_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU7082487.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            59673..60185
                     /locus_tag="VV588_000060"
     CDS             59673..60185
                     /locus_tag="VV588_000060"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU7082488.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            60367..61311
                     /locus_tag="VV588_000061"
     CDS             60367..61311
                     /locus_tag="VV588_000061"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU7082489.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            61320..61997
                     /locus_tag="VV588_000062"
     CDS             61320..61997
                     /locus_tag="VV588_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU7082490.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            62095..62853
                     /locus_tag="VV588_000063"
     CDS             62095..62853
                     /locus_tag="VV588_000063"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU7082491.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            62891..64396
                     /gene="lytC"
                     /locus_tag="VV588_000064"
     CDS             62891..64396
                     /gene="lytC"
                     /locus_tag="VV588_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU7082492.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRNGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            64892..65410
                     /locus_tag="VV588_000065"
     CDS             64892..65410
                     /locus_tag="VV588_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU7082493.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            65540..66046
                     /locus_tag="VV588_000066"
     CDS             65540..66046
                     /locus_tag="VV588_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU7082494.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            66046..66216
                     /locus_tag="VV588_000067"
     CDS             66046..66216
                     /locus_tag="VV588_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082495.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            66248..67480
                     /gene="clpX"
                     /locus_tag="VV588_000068"
     CDS             66248..67480
                     /gene="clpX"
                     /locus_tag="VV588_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU7082496.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            67489..68076
                     /locus_tag="VV588_000069"
     CDS             67489..68076
                     /locus_tag="VV588_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU7082497.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            68087..68467
                     /locus_tag="VV588_000070"
     CDS             68087..68467
                     /locus_tag="VV588_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU7082498.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            68519..69409
                     /gene="rapZ"
                     /locus_tag="VV588_000071"
     CDS             68519..69409
                     /gene="rapZ"
                     /locus_tag="VV588_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU7082499.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            69406..70383
                     /locus_tag="VV588_000072"
     CDS             69406..70383
                     /locus_tag="VV588_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU7082500.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDFRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            70380..71291
                     /gene="whiA"
                     /locus_tag="VV588_000073"
     CDS             70380..71291
                     /gene="whiA"
                     /locus_tag="VV588_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU7082501.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(71325..72293)
                     /locus_tag="VV588_000074"
     CDS             complement(71325..72293)
                     /locus_tag="VV588_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU7082502.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            72429..73286
                     /locus_tag="VV588_000075"
     CDS             72429..73286
                     /locus_tag="VV588_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU7082503.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            73273..74052
                     /locus_tag="VV588_000076"
     CDS             73273..74052
                     /locus_tag="VV588_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU7082504.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            74076..75428
                     /locus_tag="VV588_000077"
     CDS             74076..75428
                     /locus_tag="VV588_000077"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU7082505.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGNIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            75502..75876
                     /locus_tag="VV588_000078"
     CDS             75502..75876
                     /locus_tag="VV588_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU7082506.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            75878..76726
                     /locus_tag="VV588_000079"
     CDS             75878..76726
                     /locus_tag="VV588_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU7082507.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            77003..77770
                     /locus_tag="VV588_000080"
     CDS             77003..77770
                     /locus_tag="VV588_000080"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU7082508.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMHIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            77782..78966
                     /locus_tag="VV588_000081"
     CDS             77782..78966
                     /locus_tag="VV588_000081"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU7082509.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHNPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            78963..80834
                     /locus_tag="VV588_000082"
     CDS             78963..80834
                     /locus_tag="VV588_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU7082510.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(80977..82161)
                     /gene="mntE"
                     /locus_tag="VV588_000083"
     CDS             complement(80977..82161)
                     /gene="mntE"
                     /locus_tag="VV588_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU7082511.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            82465..85161
                     /locus_tag="VV588_000084"
     CDS             82465..85161
                     /locus_tag="VV588_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU7082512.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            85174..85965
                     /gene="yghU"
                     /locus_tag="VV588_000085"
     CDS             85174..85965
                     /gene="yghU"
                     /locus_tag="VV588_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU7082513.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRQTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QENLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            86081..86491
                     /locus_tag="VV588_000086"
     CDS             86081..86491
                     /locus_tag="VV588_000086"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU7082514.1"
                     /translation="MEKKIVKDNLFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            86503..88098
                     /locus_tag="VV588_000087"
     CDS             86503..88098
                     /locus_tag="VV588_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082515.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            88165..88329
                     /locus_tag="VV588_000088"
     CDS             88165..88329
                     /locus_tag="VV588_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU7082516.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            88408..89136
                     /gene="yaaA"
                     /locus_tag="VV588_000089"
     CDS             88408..89136
                     /gene="yaaA"
                     /locus_tag="VV588_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU7082517.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(89414..89962)
                     /locus_tag="VV588_000090"
     CDS             complement(89414..89962)
                     /locus_tag="VV588_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU7082518.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            90283..90792
                     /locus_tag="VV588_000091"
     CDS             90283..90792
                     /locus_tag="VV588_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU7082519.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GLWNYPTVF"
     gene            90768..91955
                     /locus_tag="VV588_000092"
     CDS             90768..91955
                     /locus_tag="VV588_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU7082520.1"
                     /translation="MELSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            91948..92313
                     /locus_tag="VV588_000093"
     CDS             91948..92313
                     /locus_tag="VV588_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU7082521.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFVIDLDGNNIEVVCHKE"
     gene            92329..93675
                     /gene="asnS"
                     /locus_tag="VV588_000094"
     CDS             92329..93675
                     /gene="asnS"
                     /locus_tag="VV588_000094"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU7082522.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            93828..94118
                     /locus_tag="VV588_000095"
     CDS             93828..94118
                     /locus_tag="VV588_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU7082523.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            94130..94600
                     /gene="ssbA"
                     /locus_tag="VV588_000096"
     CDS             94130..94600
                     /gene="ssbA"
                     /locus_tag="VV588_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU7082524.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            94632..94871
                     /locus_tag="VV588_000097"
     CDS             94632..94871
                     /locus_tag="VV588_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU7082525.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            95166..96566
                     /locus_tag="VV588_000098"
     CDS             95166..96566
                     /locus_tag="VV588_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU7082526.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            96568..96927
                     /locus_tag="VV588_000099"
     CDS             96568..96927
                     /locus_tag="VV588_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU7082527.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            96981..97730
                     /locus_tag="VV588_000100"
     CDS             96981..97730
                     /locus_tag="VV588_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU7082528.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            97720..98019
                     /locus_tag="VV588_000101"
     CDS             97720..98019
                     /locus_tag="VV588_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU7082529.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            98090..99025
                     /locus_tag="VV588_000102"
     CDS             98090..99025
                     /locus_tag="VV588_000102"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU7082530.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            99111..99623
                     /locus_tag="VV588_000103"
     CDS             99111..99623
                     /locus_tag="VV588_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU7082531.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            99648..100256
                     /locus_tag="VV588_000104"
     CDS             99648..100256
                     /locus_tag="VV588_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU7082532.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            100357..100554
                     /locus_tag="VV588_000105"
     CDS             100357..100554
                     /locus_tag="VV588_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU7082533.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(100597..102042)
                     /locus_tag="VV588_000106"
     CDS             complement(100597..102042)
                     /locus_tag="VV588_000106"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU7082534.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            102148..103770
                     /locus_tag="VV588_000107"
     CDS             102148..103770
                     /locus_tag="VV588_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU7082535.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEDSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            103973..105931
                     /locus_tag="VV588_000108"
     CDS             103973..105931
                     /locus_tag="VV588_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7082536.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            106103..107038
                     /locus_tag="VV588_000109"
     CDS             106103..107038
                     /locus_tag="VV588_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082537.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            107063..107785
                     /locus_tag="VV588_000110"
     CDS             107063..107785
                     /locus_tag="VV588_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082538.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLEQFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            107942..109036
                     /locus_tag="VV588_000111"
     CDS             107942..109036
                     /locus_tag="VV588_000111"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU7082539.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            109044..110210
                     /locus_tag="VV588_000112"
     CDS             109044..110210
                     /locus_tag="VV588_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU7082540.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQVVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGDAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            110303..113401
                     /locus_tag="VV588_000113"
     CDS             110303..113401
                     /locus_tag="VV588_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU7082541.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIVQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLTYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVTVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            113449..114066
                     /locus_tag="VV588_000114"
     CDS             113449..114066
                     /locus_tag="VV588_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU7082542.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            114077..115411
                     /locus_tag="VV588_000115"
     CDS             114077..115411
                     /locus_tag="VV588_000115"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU7082543.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            115421..115885
                     /locus_tag="VV588_000116"
     CDS             115421..115885
                     /locus_tag="VV588_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7082544.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEEILLYATSQGYSMIWFNPFYLEEQ"
     gene            115882..116376
                     /locus_tag="VV588_000117"
     CDS             115882..116376
                     /locus_tag="VV588_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7082545.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            116457..118112
                     /gene="mltG"
                     /locus_tag="VV588_000118"
     CDS             116457..118112
                     /gene="mltG"
                     /locus_tag="VV588_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU7082546.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            118183..118665
                     /gene="greA"
                     /locus_tag="VV588_000119"
     CDS             118183..118665
                     /gene="greA"
                     /locus_tag="VV588_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU7082547.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        34932 a        22155 c        27039 g        34672 t
ORIGIN      
        1 tctggtttct gaaaagtatt atattatatt ttatttcata ttatacaaat ttttatttta
       61 taatatcaga aaatactttt tttaaaaagc aaatatgata caattttatt tgaaaaaaaa
      121 taaaaaagga gattttatta tgaaatcaag tggtatcgtc ggtcttgtgg gaggaatttt
      181 acttcttatt tgtccttttg tcttgttggg aacagcggta aatacagctg ctacaactct
      241 taatggagga gctactgcag gggctttttc aggtgttgcc ttactcttga ataccttgaa
      301 gattgcaaat cttgttcttg gtatcattgc tattgtttac tataaaggag ataagcatgt
      361 aggtgcagct ccgtctgtac taatgattgt ttctggtgaa gttagtctca ttccattctt
      421 aggatgagtt ggggggattc ttgctattat cggaggatct ctattccttg caacattgaa
      481 gaaattcaaa tcagaagaat aaaaggtatt ttagcatgaa aagaacaaaa aagtttatcg
      541 gtataggagt agctctatta tctctttctc ttctagttgc atgtggaaca taaagttcaa
      601 agaatacttc aacaagtaat gatgagaaga cagtagcaac atccaatagt tcaaaagaaa
      661 caatcacttt cgatacaccg gttgtaacag acgatgcgat tgaatcaata cgcacttatg
      721 cagattatat agatctttat aaaaatattt ttgatgatta ttttactaaa gctgaggaag
      781 gtttcaaagg cacagttatg gaaaataatg actcgtttac taaactaaaa gagtcaactc
      841 aaaaattatt cgatgcgcag aaaaaaaggt taaataatga agatagaata gaaacagcca
      901 aaaacaatgt gattgccaaa cattgtcaaa cagtcctttc ctttttggtt ttgactagct
      961 tttttgtgaa aaattgtgta aaatagaata gataaacgag gggaaacctc ggaaaattta
     1021 aaggagaatc catctaatgg taaaattggt ttttgctcgc cacggtgagt ctgaatggaa
     1081 caaagctaac cttttcactg gttgggctga tgttgatttg tctgaaaaag gtacacaaca
     1141 agcgattgac gctggtaaat tgatcaaaga agctggtatc gaatttgacc aagcttacac
     1201 ttcagtattg aaacgtgcta tcaaaacaac taacttggct cttgaagctt ctgaccaatt
     1261 gtgggttcca gttgaaaaat catggcgctt gaacgaacgt cactacggtg gtttgactgg
     1321 taaaaacaaa gctgaagctg ctgaacaatt tggtgatgag caagttcaca tctggcgtcg
     1381 ttcatacgat gtattgcctc caaatatgga ccgtgatgat gagcactcag ctcacacaga
     1441 ccgtcgttat gcttcacttg acgactcagt aatcccagat gctgaaaact tgaaagtgac
     1501 tttggaacgt gctcttccat tctgggaaga taaaatcgct ccagctctta aagatggtaa
     1561 aaacgtattc gtaggagctc acggtaactc aatccgtgcc cttgtaaaac acatcaaagg
     1621 tttgtcagat gatgagatca tggacgtgga aatccctaac ttcccaccat tggtattcga
     1681 attcgacgaa aaattgaacg ttgtttctga atactacctt ggaaaataaa aaattgtaag
     1741 cctaggattg atttctaggc tttttatgtt agtatggaag tatgataagg aataaaaaac
     1801 aagattatgt actggcctac aaacaaccag cttcaaccac ttacatgggt tgggaagaag
     1861 aagctttacc gataggtaat ggttctttag gagcaaaagt atttggccgt ataggggctg
     1921 aacggattca atttaatgaa aaaagtctct ggtctggagg tccacttcct gatagttcag
     1981 attatcaggg tggaaatctt caggatcagt atgttttttt agctgagatt cggcaggctt
     2041 tggagaagag agattacaat ctggctaagg aactggctga gcagcaccta attgggccaa
     2101 aaacgagtca atatgggacc tatctgtctt ttggggatat tcacattgag ttcagccagc
     2161 aaggtacgac tttgtctcag gtgacggact atcagagaca gctgaatatt agtaaggcac
     2221 ttgtgacgac ttcttatgtc tataagggaa cgcgatttga acgtgaagct tttgcgagtt
     2281 ttccagatga tctcttggtt cagcgtttta ctaaggaagg ggcggaaact ctagatttta
     2341 ctatagaact atccttgacc tgtgatttgg cttctgatga aaagtatgag caggaaaaat
     2401 ctgattacaa ggagtgtaag ttggatatta ctgattctca tatcttgatg aagggaagag
     2461 ttaaggataa tgatctgcgg tttgctagtt atctagcttg ggaaacggat ggagatatta
     2521 gagtttggtc agatagggtt cagatatcag gagccagtta tgccaatctc ttcttggccg
     2581 ctaagacgga ttttgcccaa aatcctgcta gcaattatcg caagaaacta gatttagagc
     2641 aacaggtgat agacttggtg gacacagcta aagaaaaggg ctatacccaa ttgaaatcaa
     2701 ggcatatcga ggactaccaa gccttattcc agcgtgttca attggatttg gaagctgatg
     2761 ttgacgcatc cactacagat gatttgttaa aaaattataa gccacaagaa gggcaggctt
     2821 tggaggagct gttcttccag tatggacggt atttattgat tagttcgtcc agagactgcc
     2881 cagatgctct accagctaac ctacagggag tctggaatgc ggtcgacaat cctccttgga
     2941 attcggacta tcacttaaat gtcaatctgc agatgaatta ttggccagcc tatgttacca
     3001 atctcctaga ggcggtcttt ccggtcatca actatgtaga tgatttgcgt gtctatggtc
     3061 gtctagcggc tgtaaagtat gcaggaatcg tctctcagaa aggtgaggaa aatggttggt
     3121 tggttcatac tcaagcgact ccctttggtt ggacggcacc tggttgggat tactattggg
     3181 gttggtcacc agctgccaat gcgtggatga tgcaaaccgt ttatgaagcc tattcatttt
     3241 atagggacca agactatctc agggagaaaa tttatcccat gttgagggaa acggttcgtt
     3301 tttggaatgc ctttttacat aaggatcagc aggcgcagcg ttgggtgtct tctccgtctt
     3361 attctccaga acatgggccg atttcgattg gcaataccta tgaccaatct ctgatttggc
     3421 agttatttca tgattttatt caggctgctc aggaattggg actggatgag gacttgttga
     3481 ctgaggttaa ggagaagtct gatttactaa atcctttgca aatcactcaa tctggtcgaa
     3541 tcagggagtg gtatgaggag gaagagcagt attttcaaaa tgagaaagtg gaggcccagc
     3601 accggcacgc ttcccatcta gtgggactct atcctggcaa tctctttagc tacaagggac
     3661 aagagtatat tgaagcggcg cgtgctagcc tcaatgatcg tggagatggc ggcacaggct
     3721 ggtccaaggc taataagatc aatctctggg cgcgtttggg agatggcaat cgagcccata
     3781 aattattggc agagcagtta aagacatcca ccttgccaaa tctttggtgt agccatcctc
     3841 cttttcagat agatggtaat tttggtgcta ctagtggcat ggcagaaatg ttactccagt
     3901 ctcatgcagc ttatctggta cctctagctg ccctacctga tgcttggtca acaggttctg
     3961 tttcaggctt aatggcacgt ggacattttg aagtgagcat gagctgggaa gataaaaaac
     4021 tcttacagtt gaccatttta tcaaggagtg gaggagattt gcgagtttct tatccagata
     4081 ttgagaagag tgtgattaaa atgaatcaag aaaaaataaa agcgaaatgc atggggaaag
     4141 attgtatttc ggtggcaaca gcagaaggtg atcttgttca attttatttt taagaagatg
     4201 ttataaggca gtaatttgaa actgcctttt aataaggatt taagaatata agcagttttc
     4261 aactagttga aaaagcgtta taatgataat aggaagtaat actcaatgaa aatcaaagag
     4321 cacaaacaag gaagctagcc gcaggttgct caaaacagtg ttttgaggtt gcagatggaa
     4381 gctgacgtgg tttgaagaga gattttcgag gagtataatt tgtttgatag agggtgggtc
     4441 tgatggctta tattgagatg aaacactgtt acaagcgtta tcaggttggg gacacggaga
     4501 ttgtggccaa tcgtgatgtg aattttgaga ttgaaaaggg ggagctggtt attatccttg
     4561 gtgcttcagg tgcaggcaag tcaacagtgc ttaaccttct tgggggaatg gataccaatg
     4621 atgaagggga aatctggatt gatggtgtta atattgcgga ttatagttcc caccagcgca
     4681 ccaattaccg tagaaatgat gtggggtttg tttttcagtt ttataatcta gtttctaatc
     4741 tgacagctaa ggaaaatgtg gaactggctt ctgaaattgt gacagatgcc ttgaatcctg
     4801 atcaggtctt gacagatgta ggtctggctc atcgtctaaa taactttcca gcccagcttt
     4861 ctggagggga gcaacagcga gtctccattg cacgcgcggt agccaaaaat cctaaaattc
     4921 ttctttgtga tgaacctact ggagccttgg attatcagac gggcaagcag gttttgaaaa
     4981 ttctccaaga tatgtctcgt caaaagggag cgacggtgat catcgtgact cataatggag
     5041 ctttggcgcc cattgctgat cgcgtgattc atatgcacga tgccagtgtc aaggatgtgg
     5101 tgctcaacca gcatcctcag gatattgaca gtttggagta ctagtatgat caagcgaaaa
     5161 acttattgga aggacttaat tcagtccttc acaggctcca aggggtgttt tttatccatc
     5221 ttgatcctga tgatgttggg atctctagcc ttagtaggcc tcaaagtaac cagtcccaac
     5281 atggaggcga cagctaatgc ttatttaaca actgctcaaa ccttggattt ggcagtcatg
     5341 tctaactatg gcttggatca agcagaccaa gaagaactaa aacagacgga gggcgcagag
     5401 gtcgagtttg gctatttgac agatgtgact atggataatg ggcaggatgc cattcggctg
     5461 tactccaaac cagagcgaat ttcaaccttt cagctaagaa agggacgact tcctcagtca
     5521 gacaaggaaa tcgctttggc cactcatttg caaggccaat acagcgtggg acaggagatt
     5581 agttttaaag aaaaagaaga gggtcattcc tctttaaaag accatactta taccattact
     5641 ggttttgtgg attcggctga aatcctctcc cagcgagata tgggctacgc aggaagtgga
     5701 agtgggactc tgacagccta tggggtgatt ttacctagtc agtttgatca gaaagtctac
     5761 aatatagctc gtttgaaata tcaagattta gcaggtttaa atgtcttttc atcagcttat
     5821 gaagaaaaat ccaagcaaca tcaggaagag cttgaacaaa ttttatcaga taatggcaag
     5881 gtacgtctgc aacttttgaa aaaagaagga caagagtctc tagacaaggg gcaagagacc
     5941 cttgacaagg ctcagactaa tttgcaggaa ggcaagcgtc gtttagcagc tgctcaagct
     6001 cgtatacagg ctcaagaaag tcaactagcc ttgtttcctc aagttcagag agagcaggct
     6061 agtgctcaac ttacccaagc caagcaggaa ttgggcaagg aagaggacaa actaaagcaa
     6121 gctgaacaaa atctagccca agaaaaggaa aaattagaaa aacatcagca agtcttggac
     6181 gatttggcgg agccaaggta tcaggtctat aatcgtcaga ccatgccagg tggtcagggc
     6241 tatcttatgt atagcaatgc ttcatccagt attcgagcag tgggcaatat ctttcctgtg
     6301 gtactttatg ccgtagcagc catggtgacc tttacgacca tgactcgctt tgtagacgaa
     6361 gagcgaactc atgcagggat ttttaaggcc ttgggttatc gtagtaagga tattatcgcc
     6421 aagtttctcc tttatggact agtagctggg actgtcggaa cggctctagg tagtatactt
     6481 ggtcattatt tgctagccag tgtaatttca agtgtcatta caaaaggcat ggtggtggga
     6541 gaaacccaga ttcagttcta ttggacctat agcttactag cttttgtctt gagcttgttg
     6601 gcgagtgtgt taccagccta tctggtggct tggagggaac ttcatgacga agcagcccag
     6661 cttctacttc ctaaacctcc tgtcaaagga gctaaaatct tattggagcg tatcggtttt
     6721 atctggcgtc gtctcagttt tactcataag gtaacagccc gcaacatctt tcgttataag
     6781 cagagaatgt tgatgacaat ctttggtgtg gcaggttctg tagctctgct ctttgcaggt
     6841 ttgggaatcc aatcttctgt agcaggagtt ccgtctaaac agtttcaaca aatccaacag
     6901 tatcagatgc ttgtctctga aaatcctagt gcgaccaatc aggacaaggt agagctagca
     6961 gaagtgttga aagggcagga gatactagcc taccagaaaa tctattctaa agcgctatac
     7021 aaggatttca aaggcaaagc tggtcttcaa aacattactc ttatgatgat agagaaggaa
     7081 gatttgactc cctttatcca tcttcaacat catcagcagg agctgacatt aaaagatggc
     7141 atcgttatta cagctaaact cgcccagctg gcaggtgtca aggttgggca gactttagaa
     7201 attgaaggta aggaactaaa ggtcgctgct attactgaga actacgttgg tcactttatt
     7261 tatatgagtc aggctagcta tgagcaactt tacggacagc taccccaagc caacacttat
     7321 ctggtctcat taagggatac cagtgcaact agtatcgaaa gtcaggcggg cttgcttatg
     7381 aatcaatctg cggtgtccag cgttgtccaa aatgcttcag ccattcgact cttcgactct
     7441 atcgctagct cactcaatca gaccatgacc atcttggtca tcgtatcggt tctattagct
     7501 attgtcatcc tttacaatct gaccaatatc aacgtagctg agagaatccg tgaactctcc
     7561 actatcaagg ttcttggttt tcataataat gaagtcaccc tctacattta ccgtgagacg
     7621 attgtgctgt cccttgtggg aatcgtactt ggtctgatag ctggtttcta tttacaccaa
     7681 tttttgattc aaatgatttc gcctgcgact attctctttt atccgcaggt aggctgggaa
     7741 gtctatgtaa tcccagtggc agcagtaagc atcattttga ccttgcttgg tttcttcgtc
     7801 aattattatc tgagaaaggt tgatatgtta gaagccctga aatctgtaga gtaaggtagt
     7861 tatttttagc tgattgaact tctatttact aatattcaaa aatcctccgt ttcaaagagc
     7921 agggaactct ttgtgacaga ggattttttc tatagggctt tagcagctgc aattgcggct
     7981 tcgaagtttg gctcagaatt gatattatcc acgtattcaa cgtagcgaat cgtattgtca
     8041 gtatcgagga caaagactgc gcgtgctaat aggtgccatt cgttgatcaa gagggcataa
     8101 tcgtgcccga aagaatggtc aaagtagtct gaaagcataa tggcattgtc aaggccttca
     8161 gcaccgcacc aacgtttttg agcaaaaggt aggtccattg aaacagtcaa tacgaccgtg
     8221 ttgtccagtc cagccaattc ttcattaaaa cgacgtgttt gagttgagca gatgcctgta
     8281 tcgatagaag gaacgacact caagactttt ttcttgccat caaaatcagc cagagatttt
     8341 ttagaaagat ctgttgtagt aagagaaaaa tcaagcgcct tgtcgccgac ttgtagttgt
     8401 ttacctgtaa agctcacagg atttccgaga aaagttacca taggatactc caatcttttt
     8461 tcttccattg tatctgaaac agtcagaatt ttccaatgat ttgaccggaa atgtgggcat
     8521 agaaaaaacg ccagctcata tgagaatgac gtttttcaga ggcttatttt gccaatcctt
     8581 cagcaatctt gtcaaggttg tatttcatca tgctgtagta gctgtcgcct tctttacctt
     8641 gttctgcgat agagtcagta aagatttgtg cgtagattgg gatgtttgtg tcttgagaaa
     8701 cggttttcat tggacggtca tccacacttg attctacaaa gagtgatgga acttttgttt
     8761 ggcgaagttt ttcaaccaag gtcttgattt gttcaggagt tccttcttct tcagtattga
     8821 tttcccagat gtaggcactt ggaacaccat aggctttaga gaagtatttg aatgctcctt
     8881 cgctggttac aatgagtttc ttttcagcag ggatcttatt aaatttatcc ttactttctt
     8941 tatcaagttt gtctaactta tcagtatatt ctttgagatt tttttcatag aattctttat
     9001 tgttagggtc tttggcgctc aattgtttgg cgatattttt agcaaaaata ataccgtttt
     9061 caaggttaag ccaagcgtgt gggtcttctt ttcctttttc attttgacct tcaaggtaga
     9121 taacatcaac gccgtcgctg actgcgaagt agtctttgtt ttcagttttc ttggcatttt
     9181 ctaccaattt tgtaaaccaa gcattgccac ctgtttcaag gttgataccg ttatagaaaa
     9241 tcaaatcagc ctcagaagtt ttcttaacgt cttcaggaag tggttcgtat tcgtgtgggt
     9301 cttgcccaat cggaacgata ctatgaaggt caattttgtc accagcaata tttttagtaa
     9361 tatcagcgat gattgagttt gtagcaacaa cttttagttt ttgaccagaa gttgttgctt
     9421 tttttccgct agcacatgct acaagaatga ttgcagaaag aaagagaacg agtaatgtac
     9481 ctaatttttt cattagatcc tccaatttat tagggctttg ccccttattt taacaaatgt
     9541 ttatttttca gtttcaaata tcgttgtttg ggagcgataa agaagctaat gagaaagaaa
     9601 ctagcagctg taagcacgat actagaacct gccgcaacat taaaactata gccaataaag
     9661 agtcccaaaa ctgaagcagt agctccgaag gttgaggaaa ggaaaatcat gcttttcaga
     9721 ctattagcat acagataagc agttgcagct ggggtaatca gcatggctac aatcaggata
     9781 gttccgacac tttgcatggc tgtcacagac acgagagtca ggagtaccat gagaaggtag
     9841 tgatagaaat tgacaggcat tcccatggct ttagccaaga gttcatcaaa ggaagttatc
     9901 aagagttgct tgaagaaaat ccagattaac aagaggatgg ctgcccccac acccatagta
     9961 ataaacatat ccgtatcttg gacggccagg atattaccaa aaaggatatg gaaaaggtca
    10021 gttgaacttt tagcgacacc aatcaagatg ataccgaggg ctaagaaaga agaaaaggta
    10081 atgccgatgg cggtatcgct tttgataatc gagtttcctt tgatgtaggt aatgatgatg
    10141 gcagctagca atccaaagac aatggctccg ataaagaagt caaggcccaa gatgaaggag
    10201 agggctacac ctggtaagac agcatgtgaa atggcatctc ccatgagtga catcccgcgt
    10261 agaataatga aacatcccac ggctccagct acaatcccga cgacaatagc tgttatcaag
    10321 gcattttgta ggaaatggaa tttttgcaat ccatcgataa attctgcaat cataggtcac
    10381 ctccattgaa aaagagttga ttaccgtaag cttcttttag attggtttcg gtaaaagttt
    10441 cttttgttgg accaaaggca atcacttctc gattgacaag taagacttga tcgaagtagt
    10501 ggggaatctt gctgaggtcg tggtgaacga tgagaaccgt cttcccagct tttttcaaat
    10561 ctctcagcgt attcatgatg atttcctcac tgacagagtc aatcccagca aagggttcat
    10621 ccaagaggat atagtcggct tcctgcacca aacatctggc aatcaagacc cgctggaatt
    10681 gacctccaga cagttgacta atttgacgtt cagcgtagtc agctaggccg acgatttcaa
    10741 gggcctcttg cactttcttc caatgtttag cctttaaact tcgaaagaga ggaatagagg
    10801 gaaatagtcc taacgagacg cattccttga ccttgatggg aaagttgtag tcgatattga
    10861 ttttttgttc gacataggca attcggtgta aggatttttt aacttccttg tcatcgagaa
    10921 atgcctgacc ttgatgtggg ataattccca gcataccttt taatagtgtt gatttcccag
    10981 cgccgtttgg accaatgatg ccggtaattg ttggtccatg gagcactagt gaaatatcct
    11041 taagtgccaa cgtttctttg taggagacac tgaggttttc gatacgtatc ataaacttgt
    11101 attcctcctg tctcttaata tacattaaaa aaaaaattaa gtcaagttaa tttttgaaaa
    11161 aattaaaata ataactgaaa aatagattct aaagataact ttcaggataa atttctaaat
    11221 tataaaacgc atagtatcaa gtgtaaaaaa cttggaatta tgcgttttat catggaaaga
    11281 ttttttataa tagctaaaaa ataatagtta aatggttatt aattgcattc cctagtgatt
    11341 tttgttaaga taaatgcaaa tacaaatgaa agcgagaaca agatgacacg ttatcaagat
    11401 gatttttatg atgctatcaa tggagaatgg caacagacag ctgaaatccc agcagataag
    11461 tctcaaactg gaggttttgt tgatttagac caggaaattg aagacctgat gctggcgaca
    11521 acagacaagt ggttagcagg tgaagaagtg cctgaggatg ctatcttgga aaactttgtc
    11581 aaataccacc gcctagttcg tgattttgac aagagagaag ctgacggtat cacacctgtc
    11641 ttaccactcc ttaaagaatt ccaagaattg gaaacttttg cggattttac agctaaacta
    11701 gcagagtttg agcttgcagg aaaaccaaac ttccttcctt ttggtgtatc gccagacttt
    11761 atggatgcta gaatcaatgt tctatgggct agcgctccaa gcacaatctt gccagatacg
    11821 acctactatg cagaagaaca tcctcagcgc gaagagctct tgactctttg gaaagaaagc
    11881 agcgcaaatc tcctcaaggc ttatgatttc tctgatgaag aaattgaaga cttgctagaa
    11941 aaaagacttg aattggaccg ccgagttgcg acagtggtgc tctctaatga agaaagttca
    12001 gaatatgcta aactctatca tccatattct tacgaagatt tcaagaaatt cgcgcctgcc
    12061 ctacctttgg atgacttctt caaagcagtt attgggcaat taccagacaa ggttattgta
    12121 gacgaggaac gtttctggca agcagcagag caattctaca gtgaggaagc ctggtctctc
    12181 cttaaagcaa ccttgatttt gagtgttgtc aatctttcaa ccagctattt aacagaggat
    12241 atccgtgttt tgtctggtgc ctacagccgt gccctttctg gagttccaga ggcaaaagat
    12301 aaggtcaaag cagcttatca tctagcacag gaacctttca agcaagccct ggggctttgg
    12361 tacgcccgtg agaagttctc tccagaagcc aaggcggatg tggagaaaaa agtggcaacc
    12421 atgattgatg tctataagga gcgtctgctt aagaatgact ggctcactcc agaaacctgt
    12481 aaacaggcta tcgtgaagct caatgtgatc aaaccttata ttggctatcc agaagaattg
    12541 cctgcacgtt acaaggataa ggtagtgaat gaaactgcca gtctttttga gaatgctcta
    12601 gcctttgcgc gtgtggaaat caagcacagt tggagtaagt ggaaccagcc tgtagactat
    12661 aaggaatggg gcatgcctgc tcatatggtc aatgcctact acaatcctca gaagaacctg
    12721 attgtctttc cagcggccat tttacaggcg cctttctatg acttgcatca gtcatcttct
    12781 gctaactacg gtggtattgg ggcagtgatt gcccatgaaa tttcccacgc ctttgatact
    12841 aacggggctt cctttgacga aaatggtagc ctcaaggatt ggtggacaga gagcgactat
    12901 gctgccttca aggagaaaac acaaaaagtc attgaccaat ttgatggaca ggattcttat
    12961 ggagcaacca ttaacggtaa attgactgta tcagaaaacg tggctgactt gggaggaatc
    13021 gcagcagcgc ttgaagcagc taagagagaa gcagacttct cagcagaaga gttcttctac
    13081 aacttcggtc gcatctggcg catgaaaggt cgtccagaat ttatgaaact tttggctagc
    13141 gtcgatgtgc acgcaccagc caaactccgt gtcaatgtgc aagtaccaaa cttcgacgat
    13201 ttctttacaa cctatgatgt caaagaagga gacggaatgt ggcgttcacc agaggagcgc
    13261 gtgattattt ggtaatacaa aaaatctagt catcagaaaa aaggcatcca atcacgtgtg
    13321 aaaaccttga taggatgcct tttgtaatag aaagatttgc tggatagttt acttaaattt
    13381 cgattgtcat catcttgcta gaaaaaggga ttgaaggcct tttcgtgagc gatagtagta
    13441 gctggaccat gtcctggata gacatcgtag tttggtaggg tgaagagttg ggtctggata
    13501 ctatgaagga gttgctccat gctaccagtc ggaaggtcgg tccgtccgat agtttcgcgg
    13561 aatagagcat ctcccgtcaa gactaggtga gcatcaggaa agactaggga aacaccaccg
    13621 atagagtgcc ctggggtcgg tagaacctta aaacgaaatt cctctagttg gtattcttcg
    13681 tgaaagacaa aggtgtgttc tgcaggtttt gtgaccacat ctgccatatc atcgtggcga
    13741 gggagaccgg agagattatc gacaggagtg tagagccagc tggcttcgct ctctgcgata
    13801 tagacaggag gattgccaaa cgtctcgcga accaagtcca gactcatgat atggtcataa
    13861 tgggcgtggg tcaagagaat agcacagatc ggtttgttga tcttctcgat tgtctgacga
    13921 atggcttccc aatgactacc aggatcgacg acgatgaggt gcttttcgcc ttctagataa
    13981 taggtatttt cataggcaac aggattcacg gttttatgga ttttcatact agctccaatc
    14041 tcaaagaatg tactaatact cttcgaaaat ctcttcaaac cgcgtcaact ttatctgcaa
    14101 cctcaaagca gtgctttgaa cagcctgcgg ctagctttct agtttgctct ttgattttca
    14161 ttgagtataa attaagtata gcacagttag ggagaatagg taaggattta aaatgaactt
    14221 aaaaaccagc atgactagat gaagacaggc tggttatcaa tttatcaata ttggaaaggt
    14281 gtcaattgcc cttcataggt tgcataaact ccgtcattag cttgtttgat agacgtgatg
    14341 tttagagtgc taccgtagtt ggcttctcat ttgtcgctat attcactata agttatccta
    14401 ctgggcaggt tctggtcgtt agcatagtat tgaacgactg ttttttatag ttttgctggc
    14461 tgaataggaa caggcagcaa actcctaaca ttaggagagc aaagatagaa atagcagttt
    14521 ttttcatagg tattctcctt ataaactaaa ggatagaaga aagtatcttg aggattttta
    14581 tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct tgccgtatat atgtgactga
    14641 ctttgtcagt cttatctaca acctcaaagc agtgctttga acagcctgcg gctagtttcc
    14701 tagtttgctc ttggattttc attgagtatt aattccaaaa tccagtcaag gtaccagtgt
    14761 atgtgatacg agttccaccg tttatctttc gtatcttcaa tggaattggg gaaatcagaa
    14821 agtctttggg ttacaatatg gtttccgttc ttctatctct ccttctatca cctaagttta
    14881 aaatctaact tcgtagtata ttatgggcca ataattcaga attatcaagc aattttgaat
    14941 tatttttttc ttattctgtt ccaatctagt tttcatattc ttaaaaaagt gataaaatgg
    15001 taggaagaat tggagagtag agatgccgaa agaagtgaat ttaacaggcg aagaagttgt
    15061 cgctttaacc aaagaatatt taacggaaga ggatgttcat tttgtccata aggccttggt
    15121 ctatgctgtt gaatgccaca gtggtcaata tcgcaaatca ggcgagcctt atatcattca
    15181 ccctatccaa gtggcaggta ttttagctaa gctaaagctg gatgctgtaa cagtagcttg
    15241 tggattcttg catgatgtgg tggaagatac agatgcgacc ttggacgatt tggaaagaga
    15301 gtttggtcct gatgtgcggg tgattgttga cggagttacc aagcttggca aggtcgagta
    15361 caaatcgatc gaggagcaat tagcggaaaa tcatcgcaag atgctcatgg ccatgtctga
    15421 ggacatccgc gttattttgg tcaaactgtc tgaccgcttg cacaatatgc ggaccctgaa
    15481 acatcttcga aaagacaagc aggagcgtat ttccaaagaa accatggaaa tctatgcccc
    15541 acttgcccat cgtttgggga tttccagtgt caaatgggaa ttagaagact tgtctttccg
    15601 ttatctcaat ccaacggagt tttacaagat tacccatatg atgaaggaaa agcgcaggga
    15661 gcgtgaggcc ttggtggatg aggtagtcac aaaattagag gagtatacga cagaacgtca
    15721 cttgaaaggg aagatttatg gtcgtcccaa gcatatttac tcaattttcc gcaaaatgca
    15781 ggacaagaga aaacggtttg aggaaatcta tgatctgatt gctattcgtt gtattttaga
    15841 tacccaaagt gatgtttatg ccatgcttgg ttacgtgcat gaattttgga aaccgatgcc
    15901 aggtcgcttc aaagactata ttgccaaccg caaggccaat ggttatcagt ctatccatac
    15961 gactgtttat ggaccaaaag ggccgattga attccagatt cgaaccaagg aaatgcacga
    16021 ggtggctgag tacggggttg cggctcactg ggcttataag aaaggtataa aggggcaagt
    16081 taacagcaag gaatcagcta ttggaatgaa ctggatcaag gagatgatgg agctccaaga
    16141 ccaggctgat gatgctaagg aatttgtgga ctctgttaag gaaaactatt tggctgagga
    16201 gatttacgtt tttaccccag atggagctgt ccgttccctt cccaaagatt caggaccgat
    16261 tgattttgcc tacgaaatcc ataccaaggt cggtgaaaaa gcaactggtg ccaaggtcaa
    16321 tggccgcatg gttccactga caaccaagtt aaagacaggg gatcaggttg aaattatcgc
    16381 caacccgaac tcctttggac ctagccgtga ctggctcaat atggtcaaga ctagcaaggc
    16441 gcgcaataag attcgccagt tctttaaaaa ccaagataag gaattgtctg tcaacaaggg
    16501 tcgtgagatg ctgatggatc agttccaaga aaatggctat gtggcaaata aatttatgga
    16561 caagcgccac atggatcaag ttctgcaaaa gaccagttac aagacagaag actccctctt
    16621 tgcggccatt ggttttgggg aaatcggtgc gattaccgtc tttaaccgtc tgactgaaaa
    16681 ggagcgccgt gaggaagagc gtgccaaggc caaggctgag gcagaggagc ttgtcaaagg
    16741 tggcgaggtc aaggttgaaa ataaagaaac tctcaaggtc aagcatgagg ggggagtggt
    16801 tattgaaggt gcttctggtc tcctagtgcg gattgctaag tgttgtaacc ccgtgcctgg
    16861 tgacgatatt gttggctaca ttaccaaggg tcgtggtgtg gctattcacc gtgtggactg
    16921 tatgaacctg cgtgcccaag aaaactacga gcaacgtctc cttgatgtgg aatgggaaga
    16981 ccagtactct agctcaaata aggagtatat ggcccatatc gatatctacg gtctcaaccg
    17041 tacaggactg ttgaacgatg tactgcaagt tctttcaaat acaaccaaga atatttcaac
    17101 ggtcaatgcc caaccaacca aggatatgaa gtttgctaat atccatgtgt ccttcggtat
    17161 tgccaacctc tctacactga ctacggttgt cgataaaatt aagagtgtgc cagaagttta
    17221 ctctgtcaaa cggaccaacg gctagttgtc ctagctctta ctagaaaggc tattatgaaa
    17281 atcattatcc aacgggttaa aaaagcccaa gtgagtatag aaggccagat tcagggaaaa
    17341 atcaatcagg gacttttatt gctggttggt gttggaccag aggaccaaga ggaagatttg
    17401 gactatgctg tgagaaaact ggtcaatatg cgaatttttt cagacgcaga aggcaagatg
    17461 aacctatctg tcaaagatat tgaaggagaa atcctctcta tttctcagtt taccctcttt
    17521 gcggatacta agaaaggcaa tcgtccagcc tttacagggg tagctaaacc tgatatggca
    17581 tcagacttct atgatgcttt caatcaaaaa ttagcgcaag aagtgcccgt tcagacaggt
    17641 atctttggag caaatatgca ggttgagctg gttaataacg gacctgttac cattatccta
    17701 gatactaaaa agagataaga aagaccaagc ccagtcggct tggtctttct catctatcat
    17761 aaaatactcc aaaaagaaat cggttcttga tatgcttggg ggaagtctct tttcaggctt
    17821 tggcagatgc gataggaagg gatgagatgt cctaggatga ggagagttcc ctgaaggaaa
    17881 agtggaatat cacttaaaga caccaaggag agaatcatca ggctatccca taggagaatt
    17941 tgtaaagcaa aacgccagaa tctcggtcta atctgggaat agagttgact aaagtggtca
    18001 caaagttggt ttgaaagata ggtcaatagc acaggatgaa agaaaatgag ccaaccgcta
    18061 taaatcaaaa tccagtccca agtaagcccc cctttttaaa tgtcaaaaat gccagcatga
    18121 ttccatcaat gacaaggagt tgaatggttt tgatgaagat gatttttttc atgctaaaac
    18181 ctccttttcc ttagagacac tcccctacag gtattttaga atgtatattg cttagatatt
    18241 ccttatttta ttagcttttt aaggtattaa agtagttata taagtttatg aagggtatcc
    18301 tatcctgcac ggctaatttt gagttcgaaa ctgaggagtt tataactcaa aatttcgatt
    18361 aaatcagcat ttaacgatag tatgtttgtc ataaaatgat aaatttttag attgtggaaa
    18421 ttttttttta acttaattct tgattttttt tctaaatgtg atatacttaa tttacgggat
    18481 aaaaaaacca ccttagaaag gtgtgataat gtgcaaaaag agaatgttag aatgcgttta
    18541 gcgtctgaat ccagacagat attagataag cttaaagatg atgtttacaa taaattaggc
    18601 tatgaagtaa gctattccag tattgttagt caagctgtta gagaatacgt tcctaaaaaa
    18661 gaacgtatag attggataaa attaaaagag acagctatac ccttttcatc gttaaaacag
    18721 agcaataatt gggagtacca gacatcactt atgttagagg aagatgtatt aatcttactg
    18781 tctgaactac aaaatttttt cttagatgtc ttccaagcga aacgtataca tagggcattt
    18841 tgtgtacgcc tatgcttgaa agcacaattt ttattaagta ataatgattc ttaatactat
    18901 caatattaat gcggagtgta atgctccgct aaaataaaac ctattacggg ataaaaacac
    18961 tactttattt aggatggaaa gaggaacgaa tgaagatgaa agctagagat tcaccattga
    19021 attgattttg tttttagaaa aaatcaataa ttagaaaaaa tacgaggtaa aaaaatgaat
    19081 agagatgtat tagagtttct gagaacagag accgctgaaa aaattagtct ttatataagc
    19141 gaggctaata gattggaggg cgatgtaact ctactcgcac ctagttctca agatttggaa
    19201 gatattaaaa atgctatgct ttccaattct aatctcggat taaaagttgc gagactggat
    19261 gtgatgaaga aaatagcata tgcttctaca agaaatcatt atttaacagg ggctacgatt
    19321 tttggggata tttcgaaagg aacatacaat tgtgatccta aaagttatgt ctaatataag
    19381 ggaggttaat ccctcccctt gtttttgaaa atcgaaagga aaagtataaa aatgaaagtt
    19441 aatgaatatt tctggagaac gagctgtctt atactaaaaa agaagaaatc gataaaatag
    19501 tatacgtgtt agagatgtgt ttgtcgtaaa agtctggata gttttctcct aggtagtcag
    19561 ctgtcatata ataaaaagta gaatggcaag cagtgataat tggcataaga gatgaaaaac
    19621 gctgagaact aatgaaggct aagagaacaa aaaatagaaa atcaatggtg agaaccccta
    19681 aatagtagaa gcgaatcttt ttattgattt gaggataaat ctcagcgaat tgatgtttga
    19741 gtcggacgac caagagaaat agcaggagtc cttgagcaag gaagaaaatt aaaccagaga
    19801 gcaagagcca ctcaaaagat gtctcgagtc tagtgataaa aaatgcaaat agtagcaaat
    19861 caataactgc aattgctata aaatggattc tatagagttt tttcatgaca agaccttcct
    19921 cttttatcta acttcattct actccaaaag aatgggagtt acaactaaaa tgataaaaat
    19981 agcagaaggg agattctctt aagttggcta gtattcttta tttgagtttc cttctatgta
    20041 tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga tataaaagat
    20101 gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct gaacgaaatt
    20161 gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag cattggcaat
    20221 gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct tgccctcata
    20281 tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga tgatggccgc
    20341 caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag ctttccattt
    20401 ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg ccgccttatt
    20461 tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa agtaatttcc
    20521 ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa cgttggttac
    20581 ggaaatcaat ccaaagggta caagagctgt ccatggtccc cagtctacaa atttatcgag
    20641 gcgtgagttg aggtaaccag atgcaatcgc aatccaacga ccaaagcaac cccgaagagg
    20701 tcaaactatt tagatgtagc aaaaattttt agtgattttt tcataggtta aactaccttt
    20761 ctttttttca aatattctcc caccaaatga aagtaaaata aaatgataga aataaaaccc
    20821 tgaaaataaa actttcaggg ttggtagggg acttgagaaa ttagttgatt ttctcgacat
    20881 agagttgttt tgcaatgtcc atattcactt gtaaatcctc gtcgttactg aggatagtga
    20941 aggtattgct gaagccatca aactgcttga cttggagctg gtcaccgatg tgaagtgagt
    21001 gcttgtccag ataatggaga atgtcaaaac tatcgtgcac ccgagtcagg cggtaggcgc
    21061 cagcttcctt gatatcagct agtgggaggt tattgatttc aacgaggagt tctcccttgg
    21121 caggaatagt tcctccgtgg gggcaggttt tagggaaacc tagcagttta tctagtcttt
    21181 ccacgaacag gtcagagaca gtgtgttcca agacctcagc ttcctcgtga atctggtcac
    21241 ttgtatagtc taaatgatga actagaaaaa cttcaatcaa gcggtgctta cgatagagct
    21301 cagagaccag tttgagaccg aggtcagtca gtagatagcc acattccttg tcctttagga
    21361 tgagattttc acttttcatt cgtttgatca tttcagttac ggcaggggga gagacttgca
    21421 tgcgagccgc aatttccttg ttggtaatct tatgcaggtc tatgccaatt tcataaatac
    21481 attttagata gtcttctttg tttggggtca ttcgtttcct cttgtctaat atctttatct
    21541 agtatatcaa aaaaagctag atttctctag ctgtgacttt ttatgttata cttattgcaa
    21601 gagaaaaaac gaggagatgg atatgacgaa aatagctctt ctttcagata ttcatggaaa
    21661 taccaccgcc ttggaggctg ttttggcaga tgctcagcag ctaggagtgg atgaatactg
    21721 gcttttggga gatattctca tgccagggac aggacgtaga aggattttgg acttgttgga
    21781 tcaactaccg attacggcta gagttttggg aaactgggaa gacagtcttt ggcatggtgt
    21841 ccgtaaggaa ttggatagta ctcgccctag tcaacgctat ctcttgcgcc agtgccagta
    21901 tgttttagag gaaatttccc tagaagaaat tgaagtgctc cacaatcaac ctcttcaaat
    21961 tcatcgtcag tttggggatt tgacagtggg aattagccat catctgcctg ataagaactg
    22021 ggggcgagag ttgattcata ctggcaaaca agagaatttt gaccgcttgg tgactcatcc
    22081 tccctgtgat attgctgttt atggacatat tcaccagcag ttgcttcgtc acgggactgg
    22141 tgggcaattg attgtcaatc cgggttcgat tggccaacct ttctttttgg acgctcagct
    22201 acggaaggac ttgcgggccc agtatatgat tttggagttt gatggcaagg gcctggtaga
    22261 tatggacttc cgacgggtag actacgatgt ggcagctgaa ttgcagctgg ctaaagacct
    22321 gagacttccc tattttgagg tttactatga aagtctggtc aatgggatcc accatactca
    22381 tcatcaggaa tttttgagag aattggctca gaaagagggt tgcgatcggg agttagacga
    22441 ctggttgaaa agtggtaacg attgacatta caactaaaaa gggtataata atagaaaaag
    22501 aagagtagag gcagggtagc ctcgtaaaaa ggagaagagg atgcaaattc caagtagatt
    22561 taccattgcg actcatatgc tgataatcat tgccctcgag gggaaggaaa gcaaggtgac
    22621 cagtgatttt ctggctgcta gtgtcggggt caatcctgtc attatcagaa agatcttgtc
    22681 ccagttgaag aaggcagagc tgatttcagt agcgcgtgga acgggcggaa cagagattgt
    22741 caaggacctt aaggatatta gtcttttaga tgtttatcag gcggtcgaat gtcttggtaa
    22801 gacaggtcaa ctcttcagtt tccatgacaa tccgaatcca aattgccctg taggagctca
    22861 tattcatgat gttttggatc aaaaattgga gagaattcag ttgactatgg aggcagaact
    22921 tggtcagacc agtctagaaa aagtcgtggc cgatgcagag agtcagatga aggattaaga
    22981 gggataaatg ccctcttttt ttctttggat aattatgata aaatgtagct attaaaggag
    23041 taagaaatgt atctcgttat agaaattgta ttagccttta tagtgtcatt ttggaaggat
    23101 aatagaagtt tgtggaatcc agtattattt ttattatccc tcatttcaag ttatttttat
    23161 ctatcctacc ttttttataa aaatggatac gagaatgttc agttagcttt ttatgtattt
    23221 acctttgtct tacttccttt tttgcttttt ctaagtggca tctttttaat ctataatggg
    23281 gtcattttgt tgaaacgaga gggacgttcc aagccccatt atctctcaat gctctttgat
    23341 ttttattgac tattagattc tatttaaaaa gacttagaat gcacatgaaa gtatgtattc
    23401 taggtctttt gttttgtata catttaattt tcaagagtat tatctatttt tccatgcatg
    23461 gtaacgagta tcaatcaata actgggtaag gcgacccaag gtttctcttt cttctggagt
    23521 gagggattga gcttggacaa agagatgatg aatgtattca agcgccttta aggaagccaa
    23581 gtcattgata gagctaatac cagcatcaag aatagtgcca aagaagaggt cgaagtagag
    23641 ctgaagttct tcgtcaggga ctgtggccac ccattcttta aaggttgtgt ctacttgccg
    23701 gctatcactg ttggtcttat ccagttgaac gaagtgcttg tcctcaatct gccaactaaa
    23761 ggtatcgtgc tgggcgatgc cacccagggc agtactctga acgatgattt ggtgagcagg
    23821 aatttccagc atcataccga taatagaccc ttgtggaatg aatatcttgc ttctatccat
    23881 tatcctttga taacccgcag tctgtgtcaa ttcttgatgg agaccaggtg catcaaatgt
    23941 ataaactgct gtgatctgat tttgcaaact ttgctcaatt tggctagcag catagatagc
    24001 gagatttcct cccttggaat gcccagccag aataaccttt tgcttaggat gatgggcaaa
    24061 aaagttcttt aaatagcgaa gggcgtgctt ttgagcagga atttccttca tataggtcag
    24121 gtggaaatct tccttccagc caatgatact gtcatctgtc ccacgaaaga caatcagata
    24181 ggtatcgagg ctgacacgat aagtcatagc cgcaaattgc ttttgcagtt cagggtcgat
    24241 gtcgttgata aaatgggaga gtttgcaatt tttgaagcgc ttgtgttgag ccaattcatc
    24301 taataattga aggcgatttt tgctagtaag catggtgggc tctcttggaa cctgaggtgc
    24361 tagatctaaa agacgttgag gaagtgtgga gaccagatta tcaaaggaga ggtaggtgat
    24421 ttctattaag gttagaatgt ctaactcatt caagggaagg tcgtaataag aatcatatgc
    24481 gacatctttc agatagtcaa aaatattggc cataagagct cctttctttt tatttatctt
    24541 agcaaatttc cctcaaatta gctagtagca tagcctgttt gtactggcta aaaacaggct
    24601 atttcaaatt cagtttcaga ccatctagca tggaaaaatc tgttataata atggaaaagg
    24661 agaagcgcat gcacaagatt ttattaatag aagatgatca ggtcattcgt caacagattg
    24721 ggaaaatgct ctctgaatgg ggatttgaag tggtcctggt agaagacttt atggaagttt
    24781 tgagtctatt tgttcagtcg gaacctcatc tggtcctcat ggatattggt ttgcccttgt
    24841 ttaatggtta tcactggtgt caggaaatcc gcaagatttc caaggtacct atcatgtttc
    24901 tttcttcgag agaccaggct atggatattg tcatggcaat caatatgggg gcggatgact
    24961 ttgtgaccaa gccttttgac cagcaggttc ttttagctaa ggttcagggc ttgttgcgtc
    25021 gttcctatga gtttgggcgt gatgagagtt tgctggaata tgctggtgtt atcctcaata
    25081 ccaaatccat ggatttacat tatcaagggc aagtcttgaa tttgaccaag aatgaattcc
    25141 agattttacg cgtgttattt gagcatgcag gcaacatcgt agcacgtgac gacctgatgc
    25201 gggaactttg gaacagtgac tttttcattg atgataatac cctctctgtc aatgtggctc
    25261 gtttgcgtaa aaagttggag gagcagggat tggtaggatt tatcgagacc aagaaaggaa
    25321 tagggtacgg attgaagcat gcttgattgg aaacaatttt ttctagccta tctgcgctcc
    25381 cgtagtcgtc tttttatcta tctgcttttt ttggcatttc ttgtcttact ctttcagttt
    25441 ttatttgcca gtctaggaat ttacttcctc tactttttct tcttgtgttg ctttgtaacc
    25501 atcttatttt tcacttggga catattggtg gaaacgcagg tctatcgcca ggaacttctc
    25561 tatggagaga gggaagccaa gtctcctttg gaaatagctt tagcagaaaa attagaagcg
    25621 cgtgagatgg aactctatca gcagaggtca aaagcagaaa gaaaactgac ggatttgctg
    25681 gattactata ccttgtgggt tcatcagata aagaccccca ttgcagccag tcaactctta
    25741 gttgcagaag tggtcgaccg ccaactgaag cagcagctag aacaggaaat tttcaaaatc
    25801 gactcctata ccaacctagt tttacagtac ctgcgtttag aaagtttcca tgatgatttg
    25861 gtcttaaagc aggttcaaat tgaggacttg gtcaaggaaa taattcgtaa atatgctctt
    25921 ttctttattc aaaaaggctt aaatgtcaat ctacatgacc ttgataaaga aatcgtgacg
    25981 gataaaaagt ggctgctagt ggttattgag caaatcatct caaacagtct caagtacacc
    26041 aaggaaggtg gtctggagat ttatatggat gaccaagagc tttgtatcaa agatacggga
    26101 atcgggataa aaaacagtga tgtcctccga gtatttgaac gtggcttttc aggatacaat
    26161 ggccgtttga cccagcagtc ctctggactt ggcctttatc tatctaagaa aatttctgaa
    26221 gaactggggc accagattcg tatcgagtct gaggtcggaa aaggaacgac agtgcggatt
    26281 cagtttgctc aagtgaactt agtccttgag taaaaataga tgagaaaaag cctccagatt
    26341 ggaggctttt atgctagact cttatttctc aacgcgtgat ttgttggcga tatcagctag
    26401 gatagcttga acaaaattat caactgagac agtttgtgtt tctttttggc cgtagcgacg
    26461 aacgttgact gtttcgtctt ccatttcttt gtctccaaca attaattggt aaggaatctt
    26521 gctggtttgt gaagcacgga tcttgaactg cattttttca ttgcgctcat ctacgtctgc
    26581 acggacaccg cggtcacgga gtttcttggc cacttcccaa gcgtagttca cgtgtttttc
    26641 gttagatact gggatgaggg ttacttggtg tggtgccagc catgttggga aggccccctt
    26701 gtagttctca atcaagatag ctgtgaagcg ttccatagtt gagataaccc cacggtggat
    26761 catgactgga cggtgatctt cgccatcagc tccgatgtat ttgaggtcga agcgttctgg
    26821 caacaagaaa tcaagttgga tagtagaaag ggtttcttct tttccaaggg cagttttaat
    26881 ctggatatcc aattttggtc cgtagaaggc tgcttcacct tcggcttcaa agtagtccac
    26941 gcccatttca tcaagagctg cacgaagcat ggtttgggca ttttcccaca tctcatcgtt
    27001 atcaaagtac ttatgagtat cttgagggtc acgaagagag aggcggaagc ggtagtcagt
    27061 caagttgaag tcttcataaa catcgataat caactgaagg gcacgttgga attcttcttg
    27121 gatttgttct ggagtaacga ataggtgacc gtcgttgagt gacatttcac gtacacgttg
    27181 aaggccagtg agggcaccag atttttcgta acggtgcatc ataccgattt cagcgatacg
    27241 gattggcaat tcacggtaag agtgaacatg gtgtttgaaa acttggatgt ggtgcggaca
    27301 gttcattgga cgaaggacaa attcttcccc gtcacccatg tccatggttg ggaacatgtc
    27361 ttcttggtaa tgatcccagt gaccagaagt cttgtaaagc tcaacagaag caagtggtgg
    27421 agtgtagacg tgttggtagc cagaagccaa ctctttgttt acgatgtagc gttccaattc
    27481 acgacggata gtcgcaccat ttggcaacca gaatggcaaa ccttgtccca cttcttgtga
    27541 aatcataaag aggtcaagct ctttaccaag tttacggtgg tcacgttcct tagcttcttc
    27601 acgcatttga aggtagtttt tcaagtcttt cttgtcaaac caagctgtac cgtagatacg
    27661 ttgcatcata gcgttgtcgc tgtttccacg ccagtaagca ccagctacat ggagaaggtg
    27721 gaagatttgg atacgacctg ttgatggaac gtgaggtcca cggcagaggt ctacatattc
    27781 accctgacga tagatagtca aaccgccttc gtcttctgag tgttcttcaa tcaattccaa
    27841 cttgtaaggg tcatttttga agatttcacg tgcctcgtct ttagtcactt cttcacgaat
    27901 agatgggaag ttttctttga cgattttttg catttcttct tcgatacgag gaaggtcttc
    27961 gttagagatt tgaccagcta tgttgtcagt atcgtagtag aaaccatctt cgatggctgg
    28021 accaactccc aagtgaatgt ctgggaaaag acgacgagct gcttgggcga acaagtgagc
    28081 tgctgagtga cgcaagattg gaagggcatc ttcgtgatca ggtgtcacaa tttcgatgct
    28141 tccatcttca gtgatagcgc gagtagtgtc gatgagtttg ccgttgaatt taccagccaa
    28201 ggctttttta gctagggaat tgctgataga ttgggcaatt tcaaaagttg ttacgccaga
    28261 ttcgaattca cgaacagcgc catctgggaa agtaatgtta atcatgatgt tctccttttt
    28321 tattatttca tagtttctaa gcattgattt tttatcagca gactacttcc aagtcctaac
    28381 gttcaattgc ttttctttat cagagaggaa gttttccatt tccgtcagaa tgtctatatc
    28441 caaacgttga gaaagttcta atagccacca gatattttct gaaagttttt gttccagtgt
    28501 gtagggtgtt tcatcatagt agcgtccttg ctttgtcatc accaatcgtt ggaaatttcc
    28561 aatatcatta gataaagcca agaggtcttc ttctaccgtc cacttggaat catgatgctt
    28621 aacttccagt tcgtgataag cttgtcggat tgcccaactg tgctccacta attcttgcaa
    28681 ctccataatt agtatcctaa taaaaaaatg cgacatcctc gaaaggacgt cgcaacgtgg
    28741 ttccaccttc atttatgtac ctcaaaagag agggacacct ctgatcggct ctaacgtggc
    28801 caccgtttta tgttttcata aaaaactcaa gagtagtatc agtttagact tcctatgcgt
    28861 ttccagcaac cacgcactct ctagtagaaa gggactaagt gacttgtctc tatggattat
    28921 tatagcatga ttgtgagatt tttcaaggat tttgtgaaag ttttttgttt ttcatttttt
    28981 gtagaatatg cttgatgcta ataccagaat ccatgcccac cagagcaact gtttcataga
    29041 ttagcaagta aattagtata aactcaccaa agattatgat agtgaagtaa aagagcagtc
    29101 cgttaccaac taaccatcaa agtgagaaac ggaaacggta gctatagagt aacgatacaa
    29161 tcaagattac cagaggtgta aagaagagaa gattgtttat atagagtccc ttgagtgtaa
    29221 gggggtcaga aacaactagc aagaacaact cataaagtgg ccaataaata tgaccagata
    29281 gtaggggaga tgggaataga atctacgcat gataatcacc tcgttttaaa aaaaacagac
    29341 aacttagatc tcttgctatg attattataa gcatgtttaa aacaagaaag taaatttgtt
    29401 gacaaagaag atttttcttt tcactagaat catagttagt tttcttggta gaaatatttt
    29461 gataataatt aagcaagact attgacattg attattaaga gtgtcacaat tgctgtaact
    29521 aaaataatta caacaagaga ggtataaaaa atgaaactag cagttattgc agcaaatgga
    29581 caagtgggga aagcaattgt tgaagaagca gtcaaacgag gacatgaagt aacggctatt
    29641 gttcgttctg aaaacaaaag tcaagctgag tctattatta aaaaagattt atttgagttg
    29701 acaaaagatg atcttactgg atttgatgct gttatttcag cgtttggtgc ttatacacca
    29761 gatacgctac cgctccatag caaatcaatc gaactattta atcagcttct tgctggaaca
    29821 cagacacgtt ttctagttgt agggggagca gaaagtcttt atatagatga aacaaaaacg
    29881 acacgacttt tagatacgtc tgattttcct gaagaattta agtcactagc aaaagctcaa
    29941 gcggatgaat tggatcttct tcgtacaaaa aataatctca actggacttt tgtcagtcct
    30001 gctgtagatt ttattcccga tggtgaaaaa acaggaaact acattctagc aggagaaatt
    30061 tttactacta atgaaaaaag gaataagcca gattagttat gcagattatg ctattggatt
    30121 ggtagatgaa cttgaaaaag gtcatcatat aaaagaacgt atctctttac ttgaaaaata
    30181 ataactatga gagtattaat gtttgacaga aaatttaaat cttggtaaaa tagggattgt
    30241 cgtaaagaca aataacttct tcttggttac aggcatgcca acctgtcact cggatgaagc
    30301 caaataaaaa ggagaaacat catggcaatc tcaaaagaga aaaaaaatga aatcattgca
    30361 caatatgcac gtcacgaagg tgatacaggt tcagtagagg ttcaagttgc tgtccttact
    30421 tgggaaatca accaccttaa cgaacacatc aaacaacaca aaaaagacca cgctacttac
    30481 cgtggattga tgaaaaaaat cggtcgtcgt cgtaacttgc ttgcatactt gcgtaaaaac
    30541 gacgttaacc gttaccgtga gttgatcaac tctctaggac ttcgtcgcta attcaagata
    30601 caaaggccgt caaaagcaca aagcaaaaat aggaaaattg acgaagaaac ttcagtttct
    30661 aggagatttt atcttttttg ccaagtgctt aggccgtgtt caattgagca tatcttgata
    30721 ataaagctac tctaaattgg gtagcttttt tgcgttgtca ccttacctcg ctatactcaa
    30781 gtataatctt tggttacggt tcctagcact gtaaggtaaa ataaaccagc ttttctccct
    30841 tcggggagat tttttttgtt tcactgaaag tttcgtacga tcttcgcctc gtcgcctagt
    30901 ctataaacga tttatctagc aagaatcatg atgctaaggg cgtcaaaaat ccgtatgaaa
    30961 atagggaaat gacacagtgt tcgatgagca caaggagttt catctttttc actaggattt
    31021 tagcccgggc taaaatcagc tctctgactt cagagggctt ttttattgag gttttatcgg
    31081 taacaatttt ggagactaca aaaacctcaa atggtatcag ctaattacac cataaaggtg
    31141 cgcagttact cggcttttca agccgagtag ctgtatgcaa gccccctaga agagcccact
    31201 ctttacaaag taaagtatag tatgttatac tttacatgga agtagtcact gaattccagt
    31261 tagaaattac tttgtaacta cgttttgagg aggagtaaaa tgctttccta cgttcgacat
    31321 tacccactag cgatagctaa attaatgtgt ctgtgctctc ctgaaatctg ctgatttatt
    31381 actgactaat acaggaggtt ttttttatgg gacagacaat catatctgct attggtgttt
    31441 atatttccac cagtatcgat tatttaatta ttttaattat tttatttgca cagctatcac
    31501 agaataaaca gaaatggcat atttatgcgg ggcaatatct aggcacaggc ttacttgtag
    31561 gggcgagttt agttgctgct tatgtcgtta atttcgtgcc tgaagaatgg atggttggat
    31621 tgcttggttt aatccctatc tatttaggga ttcgctttgc aattgttgga gaagatgcgg
    31681 aagaagaaga ggaagaaatt attgaaagat tagaacaaag caaggcaaat caactgtttt
    31741 ggacagttac attgctgaca attgcgtctg gcggagataa tttaggtatc tatatacctt
    31801 attttgcttc gttagattgg tcacagaccc tcgtggcctt gcttgtgttt gtaatcggca
    31861 taattatctt ttgcgagatt agtcgggtgt tatcctctat tccgttaata ttcgagacaa
    31921 ttgaaaaata cgagcgaatc attgtgccct tagtattcat tctacttgga ctatacatca
    31981 tgtatgaaaa tggcacgata gagacttttc tgatcgtgta gatttttttg tttcactagg
    32041 attttagccc gagctcaaat cagctctctg attttcagag ggctttttca ttgagtataa
    32101 atggacaatc ttaaagttac tctattgtag agtggctttt gatttgatta ggagattctt
    32161 ataaatatag taaaatgaaa caaaaacagg acaaatcgat caggacagtc aaatcgattt
    32221 ctaaaaatgt tttaagaagt agaggtgtac tattctagtt tcaatttgct atataaatga
    32281 aaaccttagc tgtttggcca aggttcattt cttctatgca agttcttctc ttttcttatc
    32341 tgggttccag atgaagcttg cgataaagct aaagatgatg gttaggatag cgaggataat
    32401 agcaaggatg agggcaggga tgcggataaa ccaccagagt ggatttggtt ttttatcatt
    32461 gtgccattgt ttcgtttctt cgtccagacg ttggaattct gtttgaatac gattggcgac
    32521 tgtttcaatg ccttcatcat tcattttctt gatatctgag atatcgattg gatttccaaa
    32581 gttcatatcg acacgttcac ggctaatcaa gcccttcaaa atcatgggac cggtgtaggt
    32641 aaccggcatg atacggacct tggccatttt ggcaatcagt gctgcgcccc ccttgacatc
    32701 gtttgagtgg cggctaccac ttggaaacat gatgagagag cggtcacttt ttttgagaac
    32761 gttgatagga tatttgatgg ctgaggcgct gggattttca cggtcgatgg gaaaggcgcc
    32821 acacatacga atccaccaac caaagatacg gttggtaaag agttcttttt ttgccataaa
    32881 gatgaactgt tttggcttgg tcgcaaaggc catataaaca ggatcccacc aggtacggtg
    32941 aggcgcaact aaaatataat tttcatcttg attaggaatt ttatcagtat tatgatagtg
    33001 agcattgcca ttgatggacc ataagagcaa cacaactaat ccacgcaaat aagtataaaa
    33061 catgcgatct ccttcgattg ttttcttgtt attattatac cttatcaaag gagggctggc
    33121 aaacttttcc cttgactaga tgcatatttg ggatgaaatt agaattctgt taaaaaaaat
    33181 ggtataatag aatttatgga taaaaataag attatgggat taacccaaag agaagtcaag
    33241 gaaagacagg ctgagggttt ggtcaatgac tttaccgcat cagccagtac cagcacttgg
    33301 caaatcgtta aacgaaatgt ctttaccctt tttaacgctt tgaactttgc cattgctttg
    33361 gcccttgcct ttgtgcaggc ttggagcaat ctggtcttct ttgctgttat ctgctttaac
    33421 gctttttctg ggattgtgac cgagctacga gccaaacaca tggtggacaa gctcaatctc
    33481 atgaccaagg aaaaggtcaa aaccatccgt gatggtcagg aagttgctct taatcctgaa
    33541 gaattagtgc taggagatgt cattcgtttg tctgcaggag agcagattcc tagtgatgcc
    33601 ttggttttgg aaggctttgc ggaagtcaat gaagccatgt taacgggaga aagtgatttg
    33661 gtgcaaaagg aagttgacgg cttacttttg tcaggaagtt tcctagccag tgggtcagtt
    33721 ttatctcaag ttcaccatgt cggtgcagac aactatgctg ccaaactcat gcttgaggct
    33781 aagaccgtta aacccatcaa ctcccgtatc atgaaatcgc tggacaagtt ggctggtttt
    33841 actgggaaga ttatcattcc ctttggtctg gctctcttgc tggaagcctt gcttttaaaa
    33901 ggcctgcctc tcaagtcatc cgttgtaaac tcgtcgacag ctcttttggg aatgttgcct
    33961 aagggaattg cccttttgac cattacttcg ctcttgactg cagtgattaa gttgggcttg
    34021 aaaaaggtct tggtgcagga gatgtactct gttgagacct tggcgcgcgt ggatatgctc
    34081 tgtctggaca agacgggcac catcacccaa ggaaagatgc aggtggaggc tgttcttcca
    34141 ctgacggaaa cttacggtga agaggctatt gccagcatct tgactagcta catggcccat
    34201 agtgaggata agaatccaac tgcccaagcc attcgccagc gttttgtggg agatgttgct
    34261 tatcctatga tttccaatct tcccttctcg agcgaccgca agtggggggc tatggagtta
    34321 gaaggcttgg ggacagtttt cttaggggca cctgagatgt tgctggattc tgaagtccca
    34381 gaagccaggg aggccttgga gagaggatca cgtgtcttgg tcttagctct cagtcaggag
    34441 aaattagacc atcacaaacc acagaaacca tctgatattc aggctctagc cttgctggaa
    34501 atcttggacc ccattcgaga gggagcagca gagacgctgg actatctccg ttctcaggag
    34561 gtgggactca agattatctc tggtgacaat ccagttacgg tgtccagcat tgcccagaag
    34621 gctggttttg cggactatca cagctatgta gattgctcaa aaatcaccga tgaggaattg
    34681 atggccatgg cggaggagac agctattttc ggacgtgttt cccctcatca aaagaaactc
    34741 atcatccaaa cgttgaaaaa agcgggtcat acaacggcta tgacagggga cggggttaat
    34801 gatatcttgg cccttcgtga ggcggattgt tctatcgtga tggcggaggg ggatccagca
    34861 acccgtcaga ttgccaatct ggttctcttg aactcagact ttaatgatgt tcctgagatt
    34921 ctcttcgagg gtcgtcgcgt ggtcaataac attgcccaca tcgccccgat tttcttgata
    34981 aagaccatct attccttcct gttagcagtc atctgtattg ccagtgcttt actaggtcgg
    35041 tcagagtgga ttttgatttt ccccttcatt ccgatccaga ttaccatgat tgaccagttt
    35101 gtggaaggtt tcccaccatt cgttctgact tttgagcgaa atatcaaacc tgttgagcca
    35161 aatttcctca gaaaatccat gcttcgtgcc ctaccaagcg ctctcatggt cgtcttcagc
    35221 gtcctgtttg tgaaaatatt tgggagtagc caaggttggt ctgagttaga aatctcaact
    35281 ctactctatt atctcttggg gtcaattggt ttcttatccg tatttagagc ctgcatgcca
    35341 tttaccctat ggcgtgtcct cttgattgtt tggtcagtag gaggtttcct agccacagct
    35401 ctcttcccaa gaattcaaaa actgcttgaa atttcaacct taacaggaca aacattacct
    35461 gtttatggtg tcatgatgtt ggtctttacc gtgattttca tcctgaccag tcgttaccaa
    35521 gcgaaaaaat aaagaaagac tgcaatctgt ggattgcggt ttttttaggt acaagattgc
    35581 cagccgaaat gtggtataat aagaggtaat agagtttgga aagtgagaga aaatgatttc
    35641 aaagagatta gaattggtag cttcctttgt gtcacagggg gctattttac tagatgtggg
    35701 aagtgaccat gcttatctgc ctatcgagtt ggttgagaga ggccaaatca aaagcgctat
    35761 tgcaggtgag gtggtggaag gtccctatca gtctgcggtt aaaaatgttg aggctcacgg
    35821 cctaaaggag aaaatccaag tccgtttagc caatggcttg gcagcttttg aagagactga
    35881 ccaagtgtct gtcattacca ttgctggcat gggtggtcgt ttgattgcta ggattttaga
    35941 agaaggtttg gggaagttag ctaatgtaga gcgtttgatc ctccagccca ataatcgtga
    36001 agacgacttg cgtatctggc tacaggatca tggattccag attgtagcag aaagcatctt
    36061 agaagaagct ggaaagtttt atgagatttt ggtggtggaa gcaggacaaa tgaagctatc
    36121 agccagtgat gttcgctttg gtcccttctt gtccaaagaa gtcagtccag tatttgtcca
    36181 aaaatggcaa aaagaagctg agaagctaga gttcgccctc ggacaaatcc cagaaaaaaa
    36241 tctggaagaa cgtcaagttc tagtagataa gattcaagct atcaaggagg tgccccatgt
    36301 tagcaagtga agtgatccaa gcttatgaag ccttttgccc tcaggaattt tctatggagg
    36361 gagacagccg tggtctgcaa attggcactt tagacaaggg tatccaaagg gtcatggttg
    36421 ccctcgatat tcgtgaagag acagtggcag aggccattga aaagggtgtg gacttgatta
    36481 tcgtcaagca cgcgcctatc tttcgtccta tcaaggactt gcttgccagc cgtccgcaaa
    36541 atcagattta catcgacctg attaagcatg atatcgcagt ttatgtcagc cataccaata
    36601 ttgatatcgt tgaaaatggg ctcaatgact ggttttgtca gatgctagga atcgaggaga
    36661 cgacttatct gcaggaaaca ggtccagaac gtggaattgg acgtattggg aatattcagc
    36721 ctcagacatt ttgggaattg gcccaacagg tcaagcaagt ctttgaccta gatagccttc
    36781 gaatggtgca ttatcaagag aatgatttgc agaagcctat ttcaagagta gcaatttgtg
    36841 gtggaagcgg gcagtctttc tataaggatg ctttggcaaa gggggcagat gtctatatca
    36901 ctggtgatat ctactaccat actgctcagg atatgctgtc tgatggcttg ttagcattgg
    36961 atccaggtca ctatatcgaa gtgctttttg tggaaaaaat cgcagcactc cttactcaat
    37021 ggaaagagaa aaaaggctgg gaactagaga ttttacctag tcaagcatcg accaatcctt
    37081 tccgtcatat ctagttagaa agtgaagaca atgaaaaaag ttgccattat tggagcagga
    37141 attgtgggag caacagctgc ctactacctc tcgagagaaa gtgacctaga ggtgaccgtt
    37201 tttgaccatg agcaaggtca agccaccaag gccgcagcag gaattatcag tccttggctt
    37261 tcaaaacgcc gcaataaggc ctggtacaag atggcgcgat tgggggctga cttttatgtg
    37321 gatttattag ctgatttaga gaaatcagga caagaaatcg acttttacca gcgttcggga
    37381 gtctttctct tgaaaaagga tgaatccaag ttggaagaac tctatcaact ggctctccag
    37441 cgcagagaag aatctccctt gataggccag ttatccattc tggaccaagc cccagctaat
    37501 gaattattcc ctggcttgca gggattcgac aacttgctct atgcttctgg tggagcgaga
    37561 gtagatggtc acctcttagt aactcgtttg ctggaagcca gtcaggtcaa gttggtcaaa
    37621 gaaaaagtga ctctgacact cttatcatca ggctaccaga ttggcgaaga ggtgtttgat
    37681 caggttattt tggcaacggg agcttggttg ggggacatgt tagagccttt aggttatgaa
    37741 gtggatgtcc gtcctcaaaa aggacaacta cgagattatc agcttgccca agacatggaa
    37801 gattaccctg ttgtcatgcc agaaggggag tgggatttga ttccctttgc aggtgggaaa
    37861 ttatccttgg gcgctaccca tgaaaatgac atgggatttg atttgacggt agatgaaccc
    37921 ttgctccaac aaatggagga ggcggccttg cctcattacc cagttttagc tagagtgact
    37981 tcaagggctg agcgtgtggg aatccgtgcc tataccagtg atttctctcc cttctttggg
    38041 caggtgccag aattggcagg tgtctatgca gccagtggac taggttcatc aggcctcaca
    38101 actggtccta tcattggtta ccatctagcc caactgatcc aagacaagga gttgaccttg
    38161 gaccctgaaa actacccaat tgaaaactat gtcaaacgag taaaaagcga ataatactca
    38221 atgaaaatca aagaacaaac taggaaacta gccgcggatt actcaaagca ctgctttgag
    38281 gttgtggata gaactgacga agtcagctca aaacactgtt ttgaggttgt ggatagaact
    38341 gacgaagtca gtaaccatac ccatggcaag gcgacgttga cgtggtttga attggatttt
    38401 cgaagagtat aagcatttta ctgaaatttt atcaggtagt ttaggatggc aaatgacatt
    38461 ccctgtcaaa aatggtaaaa taagaaaaaa taatctgaga atcgaggaaa aaagatgcaa
    38521 gaaaagattt tggtaactgg tggtgccggt tttattggaa cccacactgt tattgaattg
    38581 atccaagcag gccatcaagt tgttgtggtg gataatcttg tcaatagcaa tcgtaagagt
    38641 ttagaagttg ttgaaagaat cacaggagtt gagattcctt tctatgaggc agatattcgt
    38701 gacacagata ccctcagaga tattttcaag caggaagaac cgactggtat cattcacttt
    38761 gctggtttga aggctgttgg cgaatcaaca cgtatccctc ttgcctacta tgacaacaat
    38821 atcgctggaa ctgtcagcct tttgaaagcc atggaagaaa acaactgtaa aaacatcatc
    38881 ttcagttctt ctgcgacagt ttacggggat ccgcacacag tgcccatctt ggaagatttc
    38941 ccactttcag tgaccaaccc atacggtcgt actaagctca tgctagagga aattttgact
    39001 gatatttaca aagcagactc agaatggaat gttgtcttgc ttcgttactt taacccaatc
    39061 ggagcccatg agagtggtga tttgggagaa aatccaaacg gtattccaaa caatctcttg
    39121 ccatatgtga ctcaagtagc cgttggaaaa ttagagcaag tgcaagtgtt tggagacgat
    39181 tacgatacgg aagatggaac aggtgttcgt gattatatcc acgttgtcga tttggctaag
    39241 ggtcacgttg cagctttgaa aaaaatccaa aaaggttcag gactaaacgt ttataacctt
    39301 ggaactggta aaggttactc agttcttgaa attatccaaa acatggaaaa agcggtggga
    39361 cgtcctattc cttaccgcat cgtagaacgt cgcccaggtg atatcgctgc ctgctactca
    39421 gacccagcaa aagctaaagc agaactcggt tgggaagcag aactcgacat cacccaaatg
    39481 tgtgaagacg catggcgttg gcaaagcaag catccaaatg gatttgaaga ctaagatgat
    39541 gatttcaatc atcgtccctt gtttaaacga agaggaagta cttcctcttt tttatcaggc
    39601 tctggaagct ttacttccag atttggaaac agaaatcgag tatgtctttg tcgatgatgg
    39661 atcaagtgat gggaccttgg aactcttaaa ggcctatcgg gagcaaaatc cggcagtcca
    39721 ttatatttct ttctctcgaa attttggcaa agaagcagcc ctttatgcag gcttgcaata
    39781 tgcgacagga gatttggtgg tggtgatgga tgcagacctc caagatcctc ctagtatgtt
    39841 gtttgagatg aaaaatgtac tagacaaaaa tgtagacttg gactgcgttg ggacacggag
    39901 aactagtcgg gagggagaac ccttctttcg cagtttctgt gctgttctct tttatcgcct
    39961 catgcaaaaa atcagcccag tagctctgcc gtcgggtgtc cgtgattttc gtatgatgag
    40021 aaggtctgta gtcgatgcca ttttaagctt gaccgagtcc aatcgttttt caaaggggct
    40081 cttcgcctgg gtgggtttca aaacctacta tttggactat ccaaatgtcg aaaggcaggc
    40141 tggcaagaca agttggagtt ttaggcaact ctttttctac tccattgaag ggattattaa
    40201 tttttcagat tttcccttga ttatagcctt tgtagctggt ctcctatctt gttttctttc
    40261 tctgctgatg accttttttg ttgtggttcg gaccctcatt ttgggcaatc cgacatctgg
    40321 ttggacctct ctgatggctg ttattctctt tcttggaggc attcaactct tgaccattgg
    40381 gattctcggc aagtatatca gtaagattta tttagagact aaaaaaagac cactttatct
    40441 tatcaaagaa aaaagtgacc ttcctgattt tacagaaaaa aataaagtga aaagactata
    40501 attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga tttaggcttc
    40561 ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga catcctgact
    40621 aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga ttccattatc
    40681 gtggtaatca aataaatcag aataagtttg gcaaagccca caggcgatac atcgttcagg
    40741 tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa aaaaaacaag
    40801 gagtaaggta tggcaaaaga accgtggcaa gaagatatct atgatcaaga agaatcaaga
    40861 gcagagcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg tattttgacg
    40921 atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct catctatcta
    40981 tcatcggggg gaagtaatcg cacagcagcc ttaaaagact ttcatgattc tgatgcaagt
    41041 gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga gccagaatct
    41101 acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt tctcgcagga
    41161 gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt agaggccttg
    41221 aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt tataaaaata
    41281 aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct tccagcggta
    41341 agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt gatacaggag
    41401 ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt gaagaagtcg
    41461 aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca gaaactggag
    41521 accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa aatgaagtga
    41581 ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaattg gtttctctcc
    41641 aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt ggaactgttg
    41701 tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag agagcagagc
    41761 gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc ctaaaaaagg
    41821 aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc aaacaagcag
    41881 aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt gaaaaaatca
    41941 aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat atcggttttt
    42001 tctaaatttg tcaaaatgct gattttaggg tataatagtt gctgttcgag aaattttgat
    42061 tttcaaagaa tagtgaatga tgataaggag aaatcatgaa caatttacca aattgtccaa
    42121 aatgtaactc agagtatgtc tacgaagacg gtgccctact ggtttgccca gagtgtgctc
    42181 atgagtggaa tcctgctgaa gttgcagaag tagaagaagg tcttgtcgct atcgatgcca
    42241 acggaaataa attggctgat ggtgatacag taactctcat caaggacttg aaagtaaaag
    42301 gtgcgccaaa agatttgaaa caagggacgc gcgtgaaaaa tatccacatc gtagaaggcg
    42361 accacaatat cgactgtaag attgatggtt ttggtgccat gaaacttaaa tcagagtttg
    42421 tgaggaagat ttaagcatgt caaaacacta taaacttgta ttttatagcc gtatcttctt
    42481 gtttctagcg gcttttacgg gagtttatct tgaaattact aagcatggtg gttttgggat
    42541 gcttctctat tacacggttc tgtccaacct cttggtaact atttttaccc tttatcttct
    42601 aaaggttatg agccgtgtag gtgaaaattg gcaaagacca agtctcttgc gcttaaaagg
    42661 tggggtcacc atgagtatca tgattacctg tgtgatttac catttcctct tggcgcccat
    42721 tgcgactaat ttctataccc tagaaaattt cctttgccac tatatcgttc ccatctggtt
    42781 tttagcggat accctctttt ttgacaaaca gggtcaatac aagatttggg atccagcagt
    42841 gtggaccatt ttaccctttc tgtatatgat gtttgctctt tttaatggct tggttctaaa
    42901 actcaatatt ccaaatgcca aggataatcc tttcccttac ttctttttga atgtgaacaa
    42961 gggttggaat gttgtgttta agtggtgtct gattatcttt gttgcctata tggtagcagg
    43021 atttattttc tactttatca agcaaatcaa gagaaagtca tcctaatact cttcgaaaat
    43081 ctcttcaaac cacgtcagtt tccatctgca acctcaaaac actgttttga acaacctgcg
    43141 gctagcttcc tagtttgctc tttgattttc attgagtata agatacaagg gattcatttt
    43201 cgaatttaag aaggagtcta caaaccaatg aggcttcttc ttttcttgct tatttgataa
    43261 ctatcaaaaa agtagaagat taagagaaat atagaaagag atttcatgaa acaattttta
    43321 gaacgggcca gcattttggc tctctccctc gttttgatta cctccttttc catttcgagt
    43381 gccctaccag ccatgtttga ctattatcag ggttattcta aggaacaaat tgagctcttg
    43441 gtgagcttgc cttcctttgg aatcatgatg atgttactgc taaatggttt cttagaaaaa
    43501 atatttcctg agcgcttaca gattagtttg ggcttgctga ttttatcatt gagcggtaca
    43561 gctcccttct ggtaccaagc ctatcccttt gtctttggag cacggcttct ctttggtttg
    43621 ggtcttggga tgatcaatgc caaggccatt tctattatca gtgaacgcta ccaaggaaaa
    43681 aggcgaattc agatgttagg gctacgcgct tctgcagagg tcgttggagc ttctctcatt
    43741 accttggccg tcggtcagtt gttggccttt ggttggacag ctatctttct agcctatagt
    43801 gctggatttt tggtgctgcc cctttatctg ctctttgtcc cttatggaaa atcaaagaaa
    43861 gaagtcaaga aaagagcgaa ggaagcaagt cgtttaactc gagaaatgaa aggcttgatt
    43921 tttaccttag ctatcgaagc ggcagttgta gtttgtacca atacagctat taccatccgt
    43981 attccaagtt tgatggtgga aagaggattg ggggatgccc agttatctag ttttgttctt
    44041 agtatcatgc agttgatcgg gattgtggct ggggtgagtt tttctttctt gatttctatc
    44101 tttaaagaga aactgctcct ctggtctggt attacctttg gcttggggca aattgtgatt
    44161 gccttgtctt catccttgtg ggtggtagta gcaggaagtg ttctggctgg atttgcctat
    44221 agtgtagtct tgacgacggt ctttcaactt gtctctgaac gaattccagc taaactcctc
    44281 aatcaagcaa cttcatttgc tgtattaggc tgtagtttcg gagcctttac gaccccattt
    44341 gttctaggtg caattggctt actaactcac aatgggatgt tggtctttag tatcttagga
    44401 ggttggttga ttgtaatctc tatctttgtc atgtacctac ttcagaagag agcttaggat
    44461 tgattcctaa gtttttcttt tgatactcaa tgaaaatcaa agagcaaact atagttgatt
    44521 gagtttggaa tagtacgctg tagctgctaa aatatttcta gaaattaatt tgactttcct
    44581 aatagagtta ttcatatctt atttcaatct actatagaaa gctagccgca ggttgctcaa
    44641 aatagtgttt tgaggttgca gatggaaact gacgtggttt gaagagattt tcgaagagta
    44701 tgagattttt atacccatac aatatttgtt ttaggtcctt gtttacagac taatttcttg
    44761 ataaaataga ggttatgacg agatataaag caactatttc ctatgatggt tatgcctttg
    44821 ctggctttca gcgccagtct catgcgcgta gcgttcagga agaaattgaa aaaaccttga
    44881 ccagattaaa taaagggcaa gccattactg ttcacggtgc tggtaggaca gatagtgggg
    44941 ttcatgccct gggacaggtc attcattttg acctgcctta tcagattgat gaggagaaac
    45001 tccgttttgc cttggatacc cagtctcctg aagatattga tgtgatttcg attgagcttg
    45061 tggcagatga ttttcattgc cgttatgcca agcatagcaa gacctatgag tttattgtgg
    45121 atagaggacg tcccaaaaat ccgatgcgcc gtcactatgc cacccacttt ccctacccac
    45181 tcgatgtgga acgaatgcag attgcaatca aaaagctaga gggaacccat gattttaccg
    45241 gttttacagc ctctgggact agtgtagagg ataaggttcg caccatcaca gaagctagtt
    45301 taatagtcga tgagacagga caatttttga cctttacctt ttccggaaat ggtttcttgt
    45361 ataaacagat tcgcaatatg gtggggactc ttctcaaaat cggtaacaac cgcatgccag
    45421 tagagcagat tgatctcatc ttggagaaga aggacaggca acttgcaggt cccactgcag
    45481 caccaaatgg tttgtattta aaggagattc gttatgaaga ataatcgtat tttagcactt
    45541 tctggaaatg atatttttag tggtggtgga ctgtcagctg atttggctac ctataccttg
    45601 aacggcttgc atgggtttgt agcagtgact tgtttgacag ccttgacaga aaaaggattt
    45661 gaagtctttc caactgatga taccattttt caacatgaat tagatagctt gcgtgatgtg
    45721 gaatttgggg gaattaagat tggtcttctc cctactgtca gtgtggctga gaaggccttg
    45781 gactttatca aacaacgccc aggagtacct gtggtgttgg atcctgtctt ggtctgcaag
    45841 gaaacgcatg atgtagctgt cagtgagctc tgccaagagt tgattcgctt tttcccttat
    45901 gtcagtgtga ttacgcctaa tctcccagaa gcagaattat tatccggtca ggaaattaaa
    45961 accttggaag acatgaaaac tgcagcgcag aaattgcatg atttaggagc gccagcagtc
    46021 attatcaagg gaggcaatcg tcttagtcag gacaaggctg tggatgtctt ttatgatgga
    46081 cagaccttta ctatcctaga aaatccagtt atccaaggcc aaaatgctgg tgcaggttgt
    46141 acctttgcct ctagcattgc cagtcacttg attaaaggtg ataaactttt gccagcagta
    46201 gaaagctcta aggctttcgt ttatcgtgct attgcacaag cagatcagta tggagtaaga
    46261 caatatgaag caaacaaaaa caactaaaat cgcccttgta tccctattaa ccgccctttc
    46321 tgtggttcta ggttatttct taaaaatccc aacacctaca ggaattctaa ctcttttaga
    46381 tgctggtgtc ttctttgcgg ccttttactt tggtagtcgt gaaggagcgg tagtcggagg
    46441 actagcaagt ttcttgattg acctcttatc aggctaccct cagtggatgt tctttagctt
    46501 ggtcaaccat ggcttgcagg gatttttcgc aggatttaaa ggaaaaagtc agtggttagg
    46561 ccttatttta gcaactattg ccatggtagg aggctacgcc ttgggttcta ctttgatgaa
    46621 tggctgggca gcagccctcc cagaaattct accaaatttc atgcaaaata tggtagggat
    46681 gattgtagga tttattctta gtcaaagtat caagaagatt aagtaatact cttcgaaaat
    46741 ctcttcaaac cacgtcagtt tccatctgca acctcaaaac actgttttga gcagcctgcg
    46801 gctagctttc tagtctgatt ttcattgagc ataaagaggt tgagtaaaaa gtctttcaaa
    46861 taagaaaaac gcatagtatc aggtgttgaa tgaacacctg atactatgcg ttttattgtg
    46921 ggaagatttt cctcattttc tagtgaaatt gaactttttc taacatcttt tgatagatga
    46981 cttcttaatc aattatcatt tccattgttg tttcttgggg tttcatccct tgtctttgat
    47041 aaaagcggag agcaccctcg ttatcattcc agacacttag ggttagatta ttgcagccaa
    47101 tttctttagc ataatagcag aaaaatgaca ataaaatagc ccctagatat tttgaaagga
    47161 aagcataggg gctatatagt ttaatcaaaa taaagcaaat ctttgctggt gcttgtaaag
    47221 aggtcgaagc catccttggt aacaacaccg cagtcttcaa tacgaacacc gactttacca
    47281 gggatataga tacctggttc aacagagaag cacatgcctt cttcgatgac catgtcgttt
    47341 ccttccatga tagatgggaa ttcatggaca tccataccga taccatgccc gagacggtgg
    47401 ttgaagtact caccataacc agctttttcg atgacctcac gggcagcgcg gtccacttca
    47461 tgagcagtca cacctggctt gataaagtca agagcagctt gttgggcttc aagagtcaag
    47521 ttgtaaatat ctttcttgaa ttggtctggt ttgccgacag cgactgtacg agtcatatct
    47581 gacgcatagc cattgaccag aacacccagg tcaaagagga gaagagcatc attttcaacc
    47641 ttattagctg ctggaatgcc gtgtggattc gcagcattat caccagtcaa gaccatggta
    47701 tcaaagctca tttcgtaacc ttcacgtttc atggcaaagt caatttgtgc gatgatatct
    47761 gtctcagtct tatcaagaga aatattgtca aaaccaacat gaacagcctt gtcagcataa
    47821 agacctgcaa ccatcatttt ttgcacttca tcagctgatt tgatgaggcg catgcgttgg
    47881 atacgaggag tgaggttgtc aaactcagca gtctcaaaaa ctgttttcaa accatggtat
    47941 ttggtcaaga tgagattgtc aaactcaaca gcgacacgtt tgaagtcaag ttgtggaaga
    48001 gcatgtttga ttttttgcca tggattttca gaatcgacat agcccactac tgggaaggaa
    48061 acggtgctac ttgcacgttc tacttcaaga gctgggacaa agaggagagg ttcctgatct
    48121 gctaggacaa agaggaacat ttggcgttca tggggatcac tgtaaaaacc agtgaggtaa
    48181 ttgattgtga cggggtcaga tacgacagcg acgtctagtt tttctgattc aagatatgtt
    48241 aggatttgtt gtaatttaga catatgctac cttctttcta tccctctatt ttggcaaaaa
    48301 atgagagaaa atgcaaggga gaagggtaaa agaaaagaca aaaaactccg acaagataac
    48361 ggagttcttt gatatcattt tcctttgttt aagaaaagtc agccttgctt ttgacgtcac
    48421 tgtactcttc agcgatttct tggctgagga tatcctcata ggcagggagt tggatgtcct
    48481 gaccatattt cttcttgagg gcagtagtaa ctaggcgata agccagattg gcattacgag
    48541 agaggatagg cccgtggaag taggaaccaa agacattctt ataatgaacc ccttcaccga
    48601 ccttttcttc gttgtttcca tttccataga caacctgtcc cagcggtttt tggtcatcag
    48661 agaggaaggt acggccttgg tgattttcaa atccatagta ggtttcatcg aaatcttcat
    48721 tgtgaatctt gatgtcaccg ataaaacggt tattggtctg gttgagcgtg tagtgtccca
    48781 tgacccctag cccttcgata cgttttcctg aagcttcaac ataatattga cccaatagtt
    48841 ggaaaccacc gcagatagcc agaactacac cgtcgttttg gatgtagttg tcaatgctct
    48901 cttttttagc aggtaggtcg tctgcaatga tactttgttc aaagtcttga ccaccaccga
    48961 aaaaggcgat gtcgtagtga ttttcatcaa agtcatcatg gagagaaacg atgtcaacgg
    49021 tcacatgggc tcccagtttt tcagccacat acttgagcat gaggatgttt ccattgtccc
    49081 cgtaggtatt catgagattt ccgtagaggt gggcaatgtt gagctgatag gggtaattgc
    49141 catcttttga ggaaagtgaa gtataaacca ttagttcatc tcctttctaa caatctgacg
    49201 actagccagc agttcacgaa attccagcat ggcagtataa gttgccagaa tataggcatg
    49261 cttgcagtct tgattctcaa tggtcttgag aacttgctcc agattactcg tttcagtgat
    49321 tttctcagct ggatagccag tcactcggag gcgacgagcg atttcagaat gacgaacacc
    49381 gccagcgttg atttcaggaa tgtccatgtc agtgatttgt tcaaagtctg catcccagat
    49441 ccagctagtg tcaattccat ctgcatagtt ggcattaagg aggacagata ggctaaatgg
    49501 ataaggtgct agtttgatca tttcgatagc ttgggttgca ccgactggat ttttaatcaa
    49561 gacaagggta cattccttgt caccgatatg aaaggtttct tggcgtccaa agacagcacg
    49621 gctcttgtca aatccctgtt tgatgagttg cgaatcggca cctaggaaac gggcgatggc
    49681 cacagcagct agggcgttat agatattata gagcccgccg atttggatac cgtattcttg
    49741 gccgtctatg acaaagcgag agcgattgtt ggtcaactca accagttttg tcaaacgata
    49801 gtcgagatca ggacgtttac atccacaacc ttcacagata taggtaccca agtttgcata
    49861 ggtattatgc tcatatttga ggatgccttg gcagtcagga cagagaatcc cttcggtatt
    49921 gtagtgagcc agttgggctg gtcctttttc caagtcaaaa ccaaaatact ctatagggtt
    49981 tggaatagtt ggcttgtaga aaagtggact gtctccgtta aggagaacag tagcagttgg
    50041 aactttccga atggcatcca atatcatgtt ataggtagta tagatttcac cgaaacggtc
    50101 catctggtca cggaagatat tagtaatgac aaaaagacta ggctggatat agtcacagat
    50161 acgagataga ctggcttcgt caatttcgag gacggcaata ttttttccag ttttagaaga
    50221 tttggctgtt aggaaggttg ttgcaatccc tgtaatcatg ttggcaccgc ttggattggt
    50281 tagaacttga ccatagacct cttttaaaat gccgacagtg agggcagttg tcagggtttt
    50341 tccatttgtt ccagtgacaa cgacaatctc gtagttctta gctaggtttt gtaaaatatc
    50401 tttatcaaat tgaagggcga ctttacctgg gagcgtactt ccacggccaa gacggcttaa
    50461 aatgaagtgg gaagaacgcc cagcaagaag gcccaaagta gtttttaagt tcatgtttct
    50521 attatatcat aaaagaggag aaagacagat ttgagattcc gcagaagtaa aaacagccca
    50581 aagagggctg ttcgatacga ttaaatctca acttaaatcg caaacaagtc attcaagttc
    50641 tcagccaagg ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg
    50701 tccatagcaa cagtgatgat gttgatgatt tcttgagaac cttctgagaa gatgcttgct
    50761 ccaagaattt cttttgtttc agtattgaca acagctttga aggcaccgcg aaggtctcca
    50821 tttacgtgac cacgaggcat ggctgcaacg gggatttcct taacagcgta tggaagtttc
    50881 aaatcagctg cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata
    50941 gtatttggca cattgagacg gtcttcaagt gtgtagctgc catctccagc aaggtagctg
    51001 taaacaacac ggaagtcatc aagtgaaatg taagtaaatt gaaggccacc gttgatatct
    51061 ccaactgcaa agacaccagg aacgtttgtt tgacagtgtt tgtctacttt aatagcacca
    51121 cgttcagtta gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt
    51181 ccagttgcgt agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact
    51241 tggtcaccat cgtttttgat ttcagtagta tggatatttt gaagcaattc aatgccatct
    51301 tcttccatgt attgtttagc aagagctgcg atggaaggtt ctgcacgagg aaggaaagta
    51361 tccaaggcat ctaggactgt gaccttgctt ccaagtttgt tgtaaaggcc ggcaaattca
    51421 agaccgatat ttccgccacc aaggattcca agtttttcag gtaatttgtc caagttttgg
    51481 atacctgttg agtcaaagat gtttttgctt gtagcaagtc cagggattgg caagacgttt
    51541 gaaacagcac cagtgttgat gacgattgtt tcagcagtca gttctttctt ttcatcacca
    51601 gcttggattt cgatgacttt atttgaaagg aagtgagctt ccgcatcaaa gatatctacg
    51661 cctgtaccag caacagtcgc atagttttta ccgttgaggc gaccagtgat cgtgttttta
    51721 gtagcaatca cttcttcaaa agacaagtcc ttttcagcag caactagcaa ggttttagtt
    51781 gggatacaac caatgttgat acaagttcca ccgtacatag ccttgctgcg ttcaacgagg
    51841 gcaacttttt tgccagctga agccaattta cctgctagtg ttttaccagc tttaccaaat
    51901 ccaataacaa ttaaatcgta tgttaacatt tatcttcctc ctattcgaat ttcattctag
    51961 cacaagaaaa aaacttttgc acaattctgc tacggaaaag acagaaaaag ataaaaacgc
    52021 tttccagaca aaaaactagt aattttttga caagcttgat aaactaaaat cctatctatt
    52081 tttatataag atagaataaa tgttcgaaaa taggaggttt tatgaaatcg aatcgttata
    52141 ttattgcctt tgctggggtc attttacact taatgctggg ttcgacttat gcttggagtg
    52201 tttatcgtaa ccctattatt gaaaaaacgg gatgggatca ggcttctgtt gcctttgcct
    52261 ttagtctagc aatcttttgt ttgggcttat cggctgcatt tatggggcgt ttggtagaaa
    52321 aatttggtcc gagagtcatg gggagtctat ctgcttttct atacgcaggt ggaaatatct
    52381 taacaggatt tgcaatagac cgtcaggagc tgtggttgtt gtatctcgct tatggcattt
    52441 taggtgggct tggtttggga gcaggctata ttacccctgt gtcgacgatt ataaaatggt
    52501 ttcctgataa acgtggtctc gcaacaggtt tagcgattat ggggtttggt tttgcttctt
    52561 tattgactag tcccatagcg caacacctca tcgcaggggt agggcttgta gaaacttttt
    52621 atattttagg agcaagttac tttattatca tgctcctagc ttcacaattc attaagcgtc
    52681 caaatgagca agagcttgca attttatctt cttcagggaa agaaaaaaca gcctctttga
    52741 cgcaaggaat ggctgcaaat caggctctaa aaagcaatcg gttttatata ctttggatta
    52801 ttttctttat caacatagct tgtggtttag gcttaatttc agcggcatcg ccaatggcac
    52861 aggagatggc tggcttgtct acaagtcatg cagcagtaat ggtgggcgtt ttagggattt
    52921 tcaatggatt tggtcgcttg ctctgggcga gcttatctga ctatatcggt cgccctctaa
    52981 cctttagtat attactgctt gttaatcttt tcttttctct ctcactttgg ctctttacag
    53041 attccgtttt atttgtagtc gctatgtcta ttttgatgac ttgctatgga gctggttttt
    53101 cattgatccc agcttatctc agtgatattt ttggaaccaa ggaattggcc gctctgcatg
    53161 gatatatttt aacagcttgg gcaatggctg gtttagcggg acctatttta ttagcagaga
    53221 cttataaaat ggctcattcg tacacacaaa ccttgttcgt ttttctcatt ttatacagta
    53281 tcgccttggc tttgtcttat tatctaggtc gttcaatcaa aaaagaaagt caaaaaccgc
    53341 ttacatgatt ttctgtagaa atggggctat cttttgctct ggtcttgtgt tatactagat
    53401 aggttgcaaa gaaaacagta cttttctttt gtggaaaaga agcaacacga ttttatatct
    53461 agttatatga aaatacgtca taaaaagaaa agtataaact aagccctata gggtggcttc
    53521 gcaccacctt tagaaagaag aataacgtga aatttaatga attaaacttg tctgctgatt
    53581 tgctggcaga aattgaaaaa gctggttttg tagaagctag tcctatccaa gaacaaacta
    53641 ttcctttggc ccttgaaggc aaggatgtta tcggtcaagc tcagactggt acaggaaaaa
    53701 ctgcagcctt tggcttgcct acccttgaaa aaatccgtac agaagaagcg actatccaag
    53761 ccttggtcat cgctccaact cgtgaactag ctgtccaaag tcaagaagaa ctcttccgct
    53821 ttggtcgtag taagggagtc aaagtccgtt cagtatatgg cggatcaagc attgaaaaac
    53881 aaattaaggc tcttaaatct ggtgcccata tcgtggtggg aactccaggt cgcctcttgg
    53941 acttgattaa acgcaaggcc ttgaaattac aaaacattga aacccttatc cttgacgaag
    54001 cggatgaaat gcttaacatg ggcttccttg aagacatcga agccattatt tcccgtgtac
    54061 ctgagaaccg tcaaactttg cttttctcag caactatgcc agatgccatc aaacgtatcg
    54121 gtgttcagtt tatgaaagcc cctgaacatg tcaagattgc agctaaggaa ttgacaacag
    54181 aattggttga ccagtactat atccgtgtta aggaacaaga aaaatttgac accatgactc
    54241 gtctcatgga tgtggcacaa ccagaactcg ctattgtatt tggtcgtacc aaacgccgtg
    54301 tggatgaatt gactcgtggt ttgaaaattc gtggcttccg tgcagaagga attcatggcg
    54361 acctagacca aaacaaacgt cttcgtgtcc ttcgtgactt taaaaatggc aatcttgatg
    54421 ttttggttgc gacagacgtt gcagcgcgtg gtttggatat ttcaggtgtg acccatgtct
    54481 acaactacga tattccacaa gatcctgaga gttatgttca ccgtatcggt cgtacaggtc
    54541 gtgctggtaa gtcaggtcaa tctattactt ttgttgctcc aaacgaaatg ggttaccttc
    54601 aaatcattga aaacttgact aagaaacgca tgaaaggtct caaacctgca agtgtagaag
    54661 aatccttcca atcaaaaaaa caggtagctc tcaagaaaat cgaacgtgat tttgcagatg
    54721 aaaccattcg tgccaacttt gagaaatttg gtaaggatgc tcgcaaattg gctgctgagt
    54781 ttactccaga agaattggca atgtatatct tgagtctgac agtccaagac ccagatagcc
    54841 ttccagaagt ggagattgca cgtgaaaaac cactaccgtt taaaccatca ggtaatggtt
    54901 tcggtggtaa agctaaggga ggtcgtggag gccgtcgtgg ggacgaccgt cgagagcgtg
    54961 atcgccgtgg caatggtcgc cgtgatgagt tcaaaaaagg aagtcgtggc aacgatcgtt
    55021 ttgataagga aaaacgttac cgtaaggata ataaaaaacc acgcaatact ttaagcgaaa
    55081 agcaaacagg ctttgttatt cgtaacaaag gcgataaata agaaaaagcg gttcaaaatg
    55141 aatcgctttt ttatataagg agaccgaatg tgaaaagaca aataaaatta ttatattatc
    55201 ttttataatg ttatgataca caaaaatagg caacttgtca atagaaaagg aacaatttaa
    55261 ttaaaaatat tctggttttt aattaaattg taagtcaatg caagtcaata aggaattttc
    55321 agataattat tgaaaaagag acgtttttat gttataatga tagcgattaa attcgaggtg
    55381 aaaaatggca catttattag aaaaaactag aaaaattaca tcaattttga aacgctcaga
    55441 ggagcagttg caggatgagc tcccttacaa cgctattacg cgtcagttag cggatattat
    55501 tcattgcaat gcctgcatta tcaatagtaa gggacgtctg cttggctatt ttatgcgtta
    55561 taaaacaaat acagatcgcg tagagcaatt cttccaaact aagattttcc cagatgacta
    55621 cgttcaaggg gctaatatga tttacgaaac agaagcaaac ttgcctgttg agcatgatat
    55681 gagtattttc cctgttgaga gtagagatga ttttccagat ggcttgacga ctattgcacc
    55741 gattcatgta tcggggattc gccttggttc tttgattatt tggcgtaatg ataaaaaatt
    55801 cgaagatgag gacttggttc ttgttgagat tgccagtacc gttgttggga ttcagcttct
    55861 taacttccaa cgtgaagaag atgagaaaaa tattcgtcgt cgtactgctg tcaccatggc
    55921 ggtcaatacc ctttcttact ccgaactccg tgctgtttca gcaattttag gggaattaaa
    55981 tggaaatgaa gggcagttga ctgcgtcagt gattgcagat cgtatcggaa tcactcgctc
    56041 tgtgattgtc aatgctcttc gtaaacttga gtctgcgggg attattgaaa gtcgctcact
    56101 tggaatgaag ggaacctatc ttaaggtctt gatttcagat atttttgaag aagtgaagaa
    56161 aagagattac taatgacaaa ggctttaatt tcgattgatt atacagaaga ttttgttgct
    56221 gatagtggga agctgacagc aggtgctcca gctcaggcga tttcggatgc cattagcaag
    56281 gtaactcgat tagcttttga acgaggagat tatatcttct ttactattga tgctcatgaa
    56341 gaaaacgatt ttttccatcc ggaaagtaag ttatttcctc ctcataatct gattgggacg
    56401 agtggacgga atttatatgg agatttgggg atcttttatc aagagcatgg ttcagacagt
    56461 cgtgtctttt ggatggataa acgccattac tcagcttttt cagggactga cctagatatt
    56521 cgtttgagag agcgtagagt gtctaccgtt atcttaacag gtgtcttgac ggatatctgt
    56581 gtcctacata cagctataga tgcctataat ctaggatatg acatcgagat tgttaaacca
    56641 gctgttgctt ccatctggcc tgaaaatcat caatttgccc taggtcattt caaaaataca
    56701 ctcggagcta agttagtaga tgaaaatcta aatgaacttt ctgagtaacc tggttggtga
    56761 aaatgaaaaa atttgaaaaa aagtgttgac aagcatccca aaagttgata tactagtaaa
    56821 gtaatcgatg cggggatggc ggaattggca gacgcgcagg actaaggatc ctgtgaccgc
    56881 tttaggtcgt gagggttcaa gtccctctct ccgcatagga aaagagttag ctaaagctag
    56941 ctcttttgta tttctctaaa aaattagaat ccagtcaaat gtagtggaga atcagcgaaa
    57001 atatgggaaa actgatcctt gtttctgctt ttgtcataga agaataataa agattatctt
    57061 cttcaaattc tccgatattc tctaaagttt tgtgcaagtt gcacagaact tttttatttt
    57121 tttggtcatc ttgccataga aatataaagc gttttcatat ataatataat tatcaaaaga
    57181 caaaaggagt tcacctcatg gtagaattga atcttaaaaa tatttacaaa aaatatccaa
    57241 acagcgaaca ctattcagtt gaagatttca acttgaacat caaagataaa gaatttatcg
    57301 ttttcgtagg accttcagga tgtggtaaat caactacact ccgtatgatt gctggtcttg
    57361 aagacattac agaaggtact gcatctatcg atggcgtggt tgtcaacgac gtagctccaa
    57421 aagaccgtga tatcgccatg gtattccaaa actacgctct ttacccacac atgactgttt
    57481 atgacaacat ggctttcggc ttgaaattgc gtaaatacag caaagaagac attaacaaac
    57541 gtgttcaaga agcagctgaa atacttggat tgaaagaatt cttggaacgt aaaccagctg
    57601 acctttcagg tggtcaacgt caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga
    57661 aagtattctt gatggacgaa cctttgtcaa acttggatgc caaacttcgt gtatcaatgc
    57721 gtgctgaaat cgctaaaatt caccgtcgta tcggagctac aactatctat gtaactcacg
    57781 accaaacaga agcgatgaca cttgcagacc gtatcgttat tatgtcagct actaagaacc
    57841 ctgctggtac aggtactatc ggacgtgtag aacaaatcgg tactcctcaa gaagtttaca
    57901 aaaatccagt taacaaattc gttgcaggat tcatcggaag cccagctatg aacttcatca
    57961 ccgtgaaatt ggttggtagc gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag
    58021 gagcattgaa agttcttcgt gaaaaaggct acgaaggaaa agaattgatc tttggtatcc
    58081 gtccagaaga cgtgaatgca gaacctgctt tccttgaaac attcccagac tgtgttgtaa
    58141 aagcgactat ctctgtatca gaactgcttg gttcagaatc tcacctttac tgccaagttg
    58201 gtaaagacga gtttgttgca aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag
    58261 ttgagcttgg atttgacttg aacaaagcac acttcttcga tgtagaaact gaaaaaacaa
    58321 tctactaaaa taaataaaat tcaaagcact acaagaaaat atatctcttt atcaattgta
    58381 gtggagagat atcagttaat ctagggagag aaacaaaatg cttctctcct ttttgctagg
    58441 gaagtcatat tatgcatcta tattgtgatg ctctttatac tcttcgaaaa tctcttcaaa
    58501 ccacgtcaac gtcgccttgc cgtacgtatg attactgatt tcgtcagttt tatctgcaac
    58561 ctcaaagatg tactttgagc agcttacggc tagtttccta gtttgctctt tgatttccat
    58621 tgagtattat tgtgagtacc atctacaagt gaagctatat gcgtaaacta cgtgagcaat
    58681 tgaattcgaa ctagagaggt aataataaat ttatgctata gttatggtga cttgtatgct
    58741 tttgattcta gtttatcaaa taatagatta gaattgtcag ataatatcat tttgtgttat
    58801 aatgaagaaa aaacagaggt gttcaaatgt cagaagcagg tcataagttt ttagcaaaat
    58861 tggggaaaaa acgcttacgt ccaggtggaa agcgtgccac agattggtta attgcagaag
    58921 gaggattttc aaaagaaaag agaatactag aggttgcgtg taatagggga actacagcaa
    58981 ttgagttggc acagcgtttt ggttgcaaga taactgctgt tgatatggat gctcaagctt
    59041 tagaagtggc taaaaaatct gctggaacgg caggtgttgc tcatttaatc agttttgaaa
    59101 gagcaaatgc aatgaaactt ccttatcaag atgctagttt tgatattgtt ataaatgaag
    59161 ctatgctgac tatgcaagcc gatcaagcta agaaaaaatg tgtaatggaa tatctaaggg
    59221 tattaaaacc tggaggtctt ctcttgacac atgatgtgct tcttaaggaa gctaaagagt
    59281 ctatcagaca ggaattatca caagcaattc atgtaaatgt aggtccttta actcaagatg
    59341 gttgggaaca ggtgatgata gaatcaggtt attgtgatgt gaaagcattg actggtgaaa
    59401 tgacattaat gaaattatcg ggtatgattt atgacgaagg tttgctagga actttgaaaa
    59461 tttgtgtaaa tgcttgtaaa aaggagaata gaaagcagtt tttaactatg tataaaatgt
    59521 ttgctaagaa taaacagaaa ttgggcttta ttgcgatggc tagttataaa tcgtcaaaac
    59581 gttagataat tattgaagtt aacttttcct tttttctttc ttaaaaaata tgctataata
    59641 gagagtaaaa aactttgaaa gaaagaaaaa agatgaattt aaaagattac attgcaacaa
    59701 ttgaaaatta tccaaaggaa ggcattacct tccgtgatat tagtcctttg atggctgatg
    59761 gaaatgctta tagctacgct gttcgtgaaa tcgttcagta tgctactgac aagaaagtcg
    59821 acatgatcgt gggacctgaa gctcgtggat ttatcgtggg ttgtccagtt gcctttgagt
    59881 tgggaattgg ttttgcgcct gttcgtaagc caggtaaatt gccacgtgaa gttatttctg
    59941 ctgactatga aaaagagtac ggtgtcgata ccttgactat gcacgcggat gccattaagc
    60001 caggtcaacg tgttcttatt gtagatgacc ttttggcgac aggtggaact gttaaggcaa
    60061 ctatcgagat gattgaaaaa cttggtggtg ttatggcagg ttgtgccttc cttgttgaat
    60121 tggatgaatt gaacggccgt gaaaaaattg gtgactacga ctacaaagtt cttatgcatt
    60181 attaatgaaa acagtcccta gggctgtttt ctctacacta ggatataaaa atagactata
    60241 actagttaga gaaaaactat aattgaaaac tatatcttct tgcagtataa taaaaggact
    60301 aagtgtttga gatttgtctt caaacatatg caattattcc tgaaagagta cagttaggag
    60361 agggttatgc cgattcgaat tgataaaaaa ttgccagctg ttgagatttt acggacagag
    60421 aatatctttg tcatggatga tcaacgtgct gcccaccaag atatccgtcc tttgaagatt
    60481 ttaattttaa atctcatgcc acagaaaatg gtcacagaga cccagttgtt gcgccacttg
    60541 gctaatacac ccctacaact ggatattgat tttctctata tggagagcca ccgttctaaa
    60601 acaactcgtt cagagcacat ggagaccttc tataaaactt ttcctgaagt caaggatgag
    60661 tattttgatg ggatgatcat cacgggtgct ccagttgagc atttaccatt tgaggaagtg
    60721 gactattggg aggaatttag acagatgctt gagtggtcta agactcatgt ctattcgacc
    60781 cttcatatct gttggggggc tcaggctggg ctttatctgc gctatggtgt agaaaaatac
    60841 cagatggaca gtaagctatc aggtatttat cctcaggaca ccctaaaaga gggtcacctt
    60901 ctatttagag gctttgatga tagctatgta tcccctcatt cacggcacac ggagatttct
    60961 aaggaagagg tcttaaacaa gaccaatctc gagattttat cagaaggacc tcaggttggg
    61021 gtttctattt tggccagtcg tgatttacga gaaatttata gttttggtca tttggagtat
    61081 gaccgtgata ccttggcaaa agagtatttt cgagatcgtg atgcaggttt cgacccacat
    61141 attccagaaa attactttaa agatgatgat gttaatcagg taccttgtct ttgttggtct
    61201 tcatctgcag ccctcttttt cagtaattgg gtaaaccatg cggtctatca ggagacgcct
    61261 tttgattgga gaaagataga agatgatgca tctgcatatg ggtatttata agaggaatta
    61321 tgacatattt agacgctttt aaatcaggta ccttggtttt accgagtgcc ctgctcttgc
    61381 attttaagga actctttcct tctagcgacg attttctggt ttggcaattt ttctatttgc
    61441 aaaatacgac aggcttagaa gaaatgtcgc caagccagat tgctgaaagg attggcaagg
    61501 aaatttcgga tgtcaaccag tccatttcta atctgacgga aaggggactg ctccagtatc
    61561 gtactatcga attaaatggc gaaattgaat tgctctttga tgctagtttg gccttggaac
    61621 gtttggatga cctgtttgga gcagttcatt caagttcaga ccagctaaca cctcaaaacc
    61681 agctcaagga tttggtggaa accttccagc aggagttggg acgattgttg acgccttttg
    61741 agattgagga tttgaccaag acactaaagg aagatggaac cagtgctgac ttgattaagg
    61801 aggctcttcg tgaagctgtt ttgaatggaa aaccaaactg gaagtacatt caggctattt
    61861 tgagaaactg gcgccatgaa ggaatcaaga gtgtggctca aattgaggcc aagagagcag
    61921 aaagagaagc aagcaatcct cagttgacac aggtatctgc agatttcaga aatgccatgg
    61981 atctctggaa ggattaatcc atgcaagtag gcttgaaatc cgagtaagat ttgcaagctg
    62041 tgtataattg tgatagaata aatagaaaat aaattgaaaa aagaggtatg tgaaatgtca
    62101 cgtaaaccat ttatcgctgg taactggaaa atgaacaaaa atccagaaga agctaaagca
    62161 ttcgttgaag cagttgcatc aaaacttcct tcatcagatc ttgttgaagc aggtatcgct
    62221 gctccagctc ttgatttgac aactgttctt gctgttgcaa aaggctcaaa ccttaaagtt
    62281 gctgctcaaa actgctactt tgaaaatgca ggtgctttca ctggtgaaac tagcccacaa
    62341 gttttgaaag aaatcggtac tgactacgtt gttatcggtc actcagaacg ccgtgactac
    62401 ttccatgaaa ctgacgaaga tatcaacaaa aaagcaaaag caatctttgc gaacggtatg
    62461 cttccaatca tctgttgtgg tgaatcactt gaaacttacg aagctggtaa agctgctgaa
    62521 ttcgtaggtg ctcaagtatc tgctgcattg gctggattga ctgctgaaca agttgctgcc
    62581 tcagttatcg cttatgagcc aatctgggct atcggtactg gtaaatcagc ttcacaagac
    62641 gatgcacaaa aaatgtgtaa agttgttcgt gacgttgtag ctgctgactt tggtcaagaa
    62701 gtcgcagaca aagttcgtgt tcaatacggt ggttctgtta aacctgaaaa tgttgcttca
    62761 tacatggctt gcccagacgt tgacggtgcc cttgtaggtg gtgcgtcact tgaagctgaa
    62821 agcttcttgg ctttgcttga ctttgtaaaa taatcagtaa gtagcaaaag ctaggtggaa
    62881 cagcattcag atgtctgtta cattttttat aggagagcaa agattgaaaa caaaaattgg
    62941 attagcaagt atctgtttac taggcttggc aactagtcat gtcgctgcaa atgaaactga
    63001 agtagcaaaa acttcgcagg atacaacgac agcttcaagt agttcagagc aaaatcagtc
    63061 ttctaataaa acgcaaacga gcgcagaagt acagactaat gctgctgccc actgggatgg
    63121 ggattattat gtaaaggatg atggttctaa agctcaaagt gaatggattt ttgacaacta
    63181 ctataaggct tggttttata ttaattcaga tggtcgttac tcgcagaatg aatggcatgg
    63241 aaattactac ctgaaatcag gtggatatat ggcccaaaac gagtggatct atgacagtaa
    63301 ttacaagagt tggttttatc tcaagtcaga tggggcttat gctcatcaag aatggcaatt
    63361 gattggaaat aagtggtact acttcaagaa gtggggttac atggctaaaa gccaatggca
    63421 aggaagttat ttcttgaatg gtcaaggagc tatgatgcaa aatgaatggc tctatgatcc
    63481 agcctattct gcttattttt atctaaaatc cgatggaact tatgctaacc aagagtggca
    63541 aaaagtgggc ggcaaatggt actatttcaa gaagtggggc tatatggctc ggaatgagtg
    63601 gcaaggcaac tactatttga ctggaagtgg tgctatggcg actgacgaag tgattatgga
    63661 tggtgctcgc tatatctttg cggcctctgg tgagctcaaa gaaaagaaag atttgaatgt
    63721 cggctgggtt cacagaaatg gtaaacgcta tttctttaat aatagagaag aacaagtggg
    63781 aaccgaacat gctaagaaaa tcattgatat tagtgagcac aatggtcgta tcaatgattg
    63841 gaaaaaggtt attgatgaga acgaggtgga tggtgtcatt gttcgtctag gttatagcgg
    63901 taaagaagac aaggaattgg cgcataacat taaggagtta aaccgtctgg gaattcctta
    63961 tggtgtctat ctctatacct atgctgaaaa tgagaccgat gctgagaatg acgctaaaca
    64021 gaccattgaa cttataaaga aatacaatat gaacctgtct taccctatct attatgatgt
    64081 tgagaactgg gaatatgtaa ataagagcaa gagagctcca agtgatacag acacttgggt
    64141 taaaatcatc aacaagtaca tggacacgat gaagcaggcg ggttatcaaa atgtgtatgt
    64201 ctatagctat cgtagtttat tacagacgcg tttaaaacac ccagatattt taaaacatgt
    64261 aaactgggta gcggcctata cgaatgcttt agaatgggaa aacccttatt attcaggaga
    64321 aaaaggttgg caatatacct cttctgaata catgaaagga atccaagggc gcgtagatgt
    64381 cagcgtttgg tattaagcga tgatttgaaa gagggatgtg atagtagcac cctctttttc
    64441 tttgttttat gatagttcat cctcgagtaa attcaagatc ttgctcggaa atgaagctta
    64501 tatagtagat tgaatataga caaatacctt gtgattggta aaacatttta gaaattcatt
    64561 tacctttcct aatcgacttg gtttcatctt atttcaatct attatagtat tggggaattt
    64621 cttcaaacca catcagcttg gtcagttcta cctgcgacct caaaacttgt gctttggtca
    64681 agctgggttt agtttcctag tttgctgatg gatttccatt gactataagc atccaaccct
    64741 ctttttgtct tctaaagaat tcttaaatta tcagtctatt gcaacttttc tcatataagt
    64801 tctttgtctt gctatttgtt ttccttagta gtatactaag gtagtaatca ttaagaagtg
    64861 gttacaaaaa ataatgaatg aggtaaagaa aatggtagaa ttgaaaaaag aagcagtaaa
    64921 agacgtaaca tcattgacaa aagcagcgcc agtagcattg gcaaaaacaa aggaagtctt
    64981 gaaccaagct gttgctgatt tgtatgtagc tcacgttgct ttgcaccaag tgcactggta
    65041 tatgcatggt cgtggtttcc ttgtatggca tccaaaaatg gatgagtaca tggaagctct
    65101 tgacggtcaa ttggatgaaa tcagcgaacg cttgattaca ctcggtggaa gcccattctc
    65161 tacattgaca gagttccttc aaaatagtga aatcgaagaa gaagctggtg aataccgtaa
    65221 tgttgaagaa agcttggaac gtgttcttgt tatctaccgt tacttgtcag aacttttcca
    65281 aaaaggtttg gatgtcactg atgaagaagg tgacgatgtg acaaacggta tctttgcagg
    65341 cgctaaaact gaaacagata aaacaatttg gatgcttgca gccgaacttg gacaagcacc
    65401 tggtttgtaa gaaataagga aacatagata aatctgtagg aaatttctta cagatttttt
    65461 ctattttgta agctattcca aaccagtctt tttttgagtt ttttgataaa atagtactat
    65521 cagtgaaaag gatggaagca tgactaagaa aatcgtagct atttgggccc aggatgaaga
    65581 gggtgtgatt ggtaaggaaa atcgtctgcc ttggcatttg ccagcagaat tgcagcactt
    65641 taaagaaaca actctgaatc atgctatctt gatggggcgt gtgacctttg atgggatggg
    65701 gcgtcgcttg cttccaaaac gggaaaccct gattttgacg cgtaatccgg aagaaaagat
    65761 agatggggtt gctacttttc aggacgtcca gtctgttctt gactggtatc aggatcaaga
    65821 aaagaatctc tacattatcg gtgggaagca aatttttcag gcttttgaac cttaccttga
    65881 tgaagtgatt gtcactcaca ttcatgctcg ggtggaagga gatacctatt tccctgaaga
    65941 gcttgacttg tctctttttg agacagtttc aagcaaattt tacgccaaag atgagaagaa
    66001 tccttatgat tttaccatcc aataccgcaa gagaaaggaa gtataatgga acggagttta
    66061 tttggtctat tcacggcttt tctgtgtttc atctgctttc tggcaggagc acaggctttt
    66121 cgtaaaaagc gttacgggct ttctatcctc ctttggttaa atgcctttac caatctggtc
    66181 aatagtattc atgcttttta catgacctta ttttagatag aatgacagta tagaatggaa
    66241 ggaaatcatg tctacaaata gaaaaaatga tatgatggtt tattgctcat tttgtggcaa
    66301 aaaccaagaa gaagtacaaa aaataattgc tggcaacaat gcttttattt gtaatgaatg
    66361 cgtggagtta gctcaggaaa tcattcgaga agaattggtt gaggaagtct tggcagactt
    66421 gtctgaggtg ccaaaaccaa ttgaactcct ccatatcttg aaccactatg taattggtca
    66481 agatcgtgcc aagcgtgcct tggcagtggc ggtttataac cactacaaac gcatcaattt
    66541 ccacgataca cgcgaagagt cagaagatgt ggatttgcag aagtcaaaca ttttgatgat
    66601 tggcccaact ggttcaggga aaactttcct tgcccagacc ttggctaaga gcttgaatgt
    66661 gccttttgct attgcggatg cgacagctct gacggaggct ggttatgtgg gtgaggacgt
    66721 ggaaaatatc ctcctcaaac tcttgcaggt tgctgacttt aacatcgaac gtgcagagcg
    66781 tggcattatc tatgtggatg aaattgacaa gattgccaag aagagtgaga atgtgtctat
    66841 cacacgtgat gtttctggtg aaggggtgca acaagccctt ctcaagatta tcgagggaac
    66901 tgttgctagc gtgccgcctc aaggtggacg caaacatcca caacaagaga tgattcaagt
    66961 ggatacaaaa aatatcctct tcatcgtggg tggtgctttt gatggtattg aagaaattgt
    67021 caaacaacgt ctgggtgaaa aagtcatcgg atttggtcaa aataataagg cgattgacga
    67081 aaacagctca tatatgcaag aaatcatcgc tgaagacatt caaaaatttg gtattatccc
    67141 tgagttgatt ggacgcttgc ctgtttttgc ggctcttgag caattgaccg ttgatgactt
    67201 ggttcgcatc ttgaaagagc caagaaatgc cttggtgaaa caataccaaa ctttgctttc
    67261 ttatgatgat gttgagttgg aatttgacga cgaagccctt caagagattg ctaataaagc
    67321 aatcgaacgg aagacagggg cgcgtggact tcgctccatt atcgaagaaa ccatgctaga
    67381 tgttatgttt gaggtgccga gtcaggaaaa tgtgaaattg gttcgcatca ctaaagaaac
    67441 tgtcgatgga acggataaac cgatcctaga aacagcctag aggtgactat ggaacttaat
    67501 acacacaatg ctgaaatctt gctcagtgca gctaataagt cccactatcc gcaggatgaa
    67561 ctgccagaga ttgccctagc agggcgttca aatgttggta aatccagctt tatcaacact
    67621 atgttgaacc gtaagaatct cgcccgtaca tcaggaaaac ctggtaaaac ccagctcctg
    67681 aactttttta acattgatga caagatgcgc tttgtggatg tgcctggtta tggctatgct
    67741 cgtgtttcta aaaaggaacg tgaaaagtgg gggtgcatga ttgaggagta cttaacgact
    67801 cgggaaaatc tccgtgcggt tgtcagtcta gttgaccttc gtcatgaccc gtcagcagat
    67861 gatgtgcaga tgtacgaatt tctcaagtat tatgagattc cagtcatcat tgtggcgacc
    67921 aaggcggaca agattcctcg tggtaaatgg aacaagcatg aatcagcaat caaaaagaaa
    67981 ttaaactttg acccgagtga cgatttcatc ctcttttcat ctgtcagcaa ggcagggatg
    68041 gatgaggctt gggatgcaat cttagaaaaa ttgtgaggaa aagaaaatgg caaaaacaat
    68101 tcatacagat aaggccccaa aggctatcgg accctatgtt caaggaaaaa tcgttggcaa
    68161 ccttttgttt gctagcggtc aagttcccct atcccctgaa actggggaaa ttgtaggaga
    68221 gaatatccaa gaacagacag agcaagtctt gaaaaacatc ggtgctattt tggcagaagc
    68281 aggaacagac tttgaccatg ttgtcaaaac aacttgtttc ttgagcgata tgaacgactt
    68341 tgttcctttt aatgaggttt accaaacggc cttcaaagag gaattcccag ctcgttcagc
    68401 tgtggaggta gctcgtcttc ctcgtgatgt aaaagtcgaa attgaagtca tcgcagagat
    68461 tggataagct agttgaagtt tggtgttgcc aaacttcttt tgatataagg agaaaaagat
    68521 gacaaagaaa caacttcact tggtgattgt gacagggatg agtggcgcag ggaaaactgt
    68581 agccattcag tccttcgagg atctaggtta tttcaccatt gataatatgc cgccagctct
    68641 cttgcctaag tttttgcagc tggttgaaat taaggaagac aatcctaagt tggccttggt
    68701 agtggatatg cgtagccgtt ctttcttttc agagattcaa gctgttttgg atgagttgga
    68761 aaatcaagat ggtttggatt tcaaaatcct ctttttggat gcggctgata aggaattggt
    68821 cgctcgttac aaggaaacca gacggagtca cccactagca gcagacggtc gtattttaga
    68881 tggaatcaag ttggaacgtg aactcttggc acctttgaaa aatatgagcc aaaatgtggt
    68941 ggatacgact gaactcactc cacgtgagct gcgcaaaacc cttgcagagc agttttcaga
    69001 ccaagaacaa gcccagtctt tccgtatcga agtcatgtct ttcggattta agtatggaat
    69061 cccgattgat gcggacttgg tctttgatgt ccgtttcttg ccaaatccct attatttacc
    69121 agaactgaga aaccaaacgg gtgtggatga acctgtttat gattatgtca tgaaccatcc
    69181 tgagtcagaa gacttttatc aacatttatt ggccttgatt gagccgattc tgccaagtta
    69241 ccaaaaggaa ggtaagtccg ttttgaccat tgccatggga tgtacgggtg gacaacaccg
    69301 tagtgtggca tttgctaaac gcttggtgca ggacttatcc aagaattggt ctgttaatga
    69361 agggcatcgc gacaaagacc gcagaaagga aacggtaaac cgttcatgag aaaaccaaag
    69421 ataacggtga ttggtggagg gactggaatt cccgtcattc taaaaagtct gcgggaaaaa
    69481 gatgtggaaa tcgcagctat cgtgacggtg gcagatgatg gtggttcttc aggtgaactc
    69541 cgaaaaaata tgcaacagtt gacaccgcca ggtgattttc gtaatgtcct tgtggccatg
    69601 tcggatatgc ctaagtttta tgagaaggtc tttcagtatc ggttctctga ggatgccgga
    69661 gcctttgctg gccatccatt gggaaatctc atcattgctg gcttgtcaga aatgcagggt
    69721 tcaacctata atgccatgca gttattgagc aaatttttcc atacaacagg gaaaatttat
    69781 ccttccagtg accatccttt gacccttcat gcagtctttc aggatgggac agaagtggct
    69841 ggagagagtc atattgtaga ccatcgaggc ataattgaca atgtctatgt gaccaatgcc
    69901 ctaaacgatg atacgcctct ggccagccgt cgagtagtgc agaccatcct tgaaagtgac
    69961 atgattgtcc tagggccagg ttctctcttt acctctattt tgcccaatat cgtgattaag
    70021 gaaattgggc gggctctttt ggaaaccaag gcagaaattg cctatgtctg caatatcatg
    70081 acccaacgtg gggagacgga acactttaca gatagcgacc acgtggaagt cttgcatcgt
    70141 caccttggtc gcccttttat cgacactgtc ttggtgaata ttgaaaaagt gcctcaggaa
    70201 tacatgaatt ccaaccgttt tgatgaatac ttggtgcaag tggaacacga ttttgtaggt
    70261 ctttgtaagc aagtttcgcg cgtgatttca tctaacttcc ttcgtctgga aaatggcggt
    70321 gccttccacg atggagattt gattgtggac gagttgatgc gcattataca ggtgaaaaaa
    70381 tgagtttcac agtagcagta aaagaagaaa tcctgggcca acaccatctg agctggcatg
    70441 aattatctgc cattatcaaa atgtctggta gcatcggtct ctcgacttcg ggcttgactt
    70501 tgtcagttgt gacagaaaat gccaaactgg cccgtcacct ctatgagtcc tttctccatt
    70561 tctatgaaat caaatctgaa attcgtcacc accaacggag caatcttcgc aagaatcgcg
    70621 tctataccgt ttttacagat gaaaaggtgc aggatttgtt aagtgatttg cacttggcag
    70681 actctttctt tggcctggaa acaggtattg atgaggcgat tttatcggat gaggaagcag
    70741 gtcgtgccta tctctgtggc gctttcttgg caaatgggag cattcgtgac cctgagtcag
    70801 gcaagtacca gttggaaatc agttctgttt atctggacca cgcgcaagga attgcctccc
    70861 ttctccaaca gtttttactg gatgccaagg tgcttgagcg caagaagggg gctgtgacct
    70921 atctccagcg agcagaagac attatggact tcttgatagt aatcggagcc atgcaggcac
    70981 gtgatgattt tgagcgggtt aagattttgc gagaaacccg taacgacctc aatcgggcta
    71041 ataatgccga gacagctaat atcgctcgga cagtttctgc cagcatgaag accattaaca
    71101 atatcagtaa aataaaagat atcatgggct tagaaaattt gccagtagat ttgcaggaag
    71161 tggcgcaact gaggattcag cacccagact actctatcca acagttggca gatagcctca
    71221 gcacccctct gaccaaaagt ggtgtcaatc acagactcag aaaaatcaat aagatagccg
    71281 atgaattata aaaccacgaa tcctatgtga ctcgtggttc ttttttataa actagtagag
    71341 tgttttggtt gtactttttg ttcagggtca atgtagttga tagcgttgtt gacagcagtt
    71401 ggagcttctc cgaggcctgt cgcaatcaga tcaatttttc cgtcatagta gcagcagtca
    71461 ccgatagcat agatacctgc ttggctggat tcctgtttgc tgttgacgat aatcttgtga
    71521 cggttgaggt cgagccccca gtttttaagg ttaccgacag aagatttgaa accatagttg
    71581 acaaagaggt ggtctaggtc aatggtttca gtttcatcag atttgacttt tgtgatttca
    71641 agtttatcaa gtgtttttcc atttccaagg agttggctag gggcgaatgg tgtcttgatg
    71701 gttacagatg attcttgcaa ggcttgaaca ctgtgttcca aggcacggaa attatctctg
    71761 cggtgaacaa gggtagttgg tgcgattttt tcaaaagcca aagcccaatc cacagccgag
    71821 tctcccccac caagaatcgt cactttctta ccagcgtatt gctgaatgtt agaaacgtgg
    71881 tagtggatat tttcatagcc ctcaacactt tcaagttcca gcggacgtgg tttgaaggca
    71941 ccgccaccca tagcgatgat aactgtttta gtcaggtgac ttcctttaga agttgtgatg
    72001 gcaaattctt cttcttgttt gtcaatctca agaaccgttt cattgagatg aataggggta
    72061 tcaaatccat ttagctgttc aatcaagcgg ttagtcaact cttctccagt caggtttggg
    72121 aagcctggta cgtctaggat ttccttttca gggtagagaa tagcaggttg tccacctagc
    72181 tggggaagag agtcgatgat ttgaaccttg gcttggcgta ggtgggcata aaaggctgca
    72241 aaaagcccga caggaccacc acccacaatg gtaatatcat agagttgaga catagtttct
    72301 cctttgtttt ttctagtcag tttattttat catatttttg ttcaatgtaa aatgaactag
    72361 gatagggaaa aaaatgccag aaaatggtat aataggacga aagtgttttg atagggagga
    72421 tatcagggat gaattttcaa caattatcca atctgcaata ttggaccagt ttgtttgcaa
    72481 gtccatggac gatagctatc aatctgattg atattttgat tgttgcttat attttatacc
    72541 attttacaaa agctattgca ggaaccaaga ttatgatttt ggtacgtgga gttttggtgt
    72601 ttattttagc tcaaatcctt gcaaatatga ttggtttgac tacgatttct tggttaatca
    72661 atcaaattat tacttatggg gttattgcgg cggttgttat cttctctcca gagattcgga
    72721 ctggtttgga acgtttggga agagcgacag atttcttttc caatgcccct attagtgctg
    72781 aggaacagat gattcgtgcc tttgttaagt ctgttgaata catgagtcct cgtaaaatcg
    72841 gggccttggt tgctattcag cgtgtacgta ccttgcagga gtatatgtcg acaggaattc
    72901 ccttggatgc taagatttct gcagaacttc tcattaacat ttttattccc aacactcccc
    72961 tacatgacgg tgcggtgatt atcaaagaag aacgtatcgc tgtgacgtct gcctatctgc
    73021 ccttgacaaa aaacacaggg atttccaagg aatttgggac cagacaccgg gcggctatcg
    73081 gtttatcaga agtctcagat gccttgactt ttgtcgtatc agaggaaacg ggaggaattt
    73141 cgataaccta taatggaagg tttaagcaca acctaacact tgatgaattt gaaacagaat
    73201 tacgtgaaat cttacttcca aaagaggaag tgggtcttag ttttaaagaa cgattgctag
    73261 gaggatggaa acatgaaaaa aaatagttta tatatcatat cctcactctt ttttgcttgt
    73321 gtcttatttg tctatgctac ggcgacgaat tttcaaaaca gtaccagtgc taggcaggta
    73381 aaaacggaaa cctatactaa tacagtaaca aatgtcccta ttgacatacg ctataatagt
    73441 gataagtatt ttattagcgg ttttgcttca gaagtatcag tggtcttgac tggtgcaaat
    73501 cgcctatcgc tagctagtga aatgcaagaa agtacacgta aattcaaggt tactgctgac
    73561 ctaacagatg ccggtgttgg aacgattgaa gttcctttga gcattgaaga tttacccaat
    73621 gggctgaccg ctgtggcgac tccgcaaaaa attacagtca agattggtaa gaaggctcaa
    73681 aaggataagg taaagattgt accagagatt gaccctagtc aaattgatag tcgggtacaa
    73741 attgaaaatg tcatggtgtc agataaagaa gtgtcgatta cgagtgacca agagacattg
    73801 gatagaattg ataagattat cgctgttttg ccaactagcg aacgtataac aggtaattac
    73861 agtggttcag tacctttgca ggcaatcgac cgcaatggtg ttgtcttacc ggcagttatc
    73921 actccgtttg atacaataat gaaggtgact acaaaaccag tagcaccaag ttcaagcaca
    73981 tcaaattcaa gtacaagcag ttcatcggag acatcttcgt caacgaaagc aactagttca
    74041 aaaacgaatt aaaaatagaa aaggatttta taacaatggg taaatatttt gggactgatg
    74101 gagtccgtgg agaagctaac ctagaactaa caccagaatt agcctttaaa ctaggacgtt
    74161 ttggaggcta tgttcttagt caacatgaaa cggaagcgcc gaaagtcttt gtaggacgtg
    74221 acacacgtat ttcaggggaa atgctggaat cggccttggt ggcaggtctc ctttcagtag
    74281 ggattcacgt atacaaactt ggtgtccttg caacaccagc agtagcttac ttggttgaaa
    74341 ctgaaggagc aagtgccggt gtcatgattt ctgctagcca caacccagcc cttgataacg
    74401 gaatcaagtt ctttggcggt gatggcttca aactagatga tgaaaaagaa gcagaaattg
    74461 aagccttgct agatgctgag gaagacactc ttcctcgtcc aagtgcagaa ggcttaggaa
    74521 ttttggtaga ttatccagaa ggcttgcgta agtatgaagg ataccttgtt tcaactggaa
    74581 ctcctcttga tggaatgaag gttgccttgg atacagctaa tggagcagct tctaccagtg
    74641 cccgtcaaat ctttgcagac cttggtgccc aattgacggt tatcggggaa acaccagacg
    74701 gtcttaacat caaccttaat gttggttcaa cacatccaga agcccttcaa gaagtggtca
    74761 aagaaagtgg gtcagctatt ggtttggcct ttgatggaga cagtgaccgc ttgattgctg
    74821 ttgatgagaa tggtaacatc gtcgatggtg acaagattat gtacatcatc ggaaaatacc
    74881 tttctgaaaa aggacaattg gctcaaaata caattgtgac aactgttatg tctaaccttg
    74941 gtttccacaa ggccttgaat cgcgaaggta ttaacaaggc agttactgca gttggtgacc
    75001 gctacgttgt tgaagaaatg agaaaatcag gctacaacct tggtggtgaa cagtctggtc
    75061 acgttatctt gatggattac aataccacag gtgatggtca attatcagca gttcaattga
    75121 ctaaaatcat gaaggaaact ggtaagagct tatcagagtt ggcggcagaa gtaacgattt
    75181 atccacaaaa attagttaat atccgagtgg aaaacgtcat gaaggaaaag gccatggaag
    75241 tgccagctat caaggccatc atcgagaaga tggaagaaga aatggcgggg aacggccgta
    75301 tccttgttcg tccaagtgga acagaacccc tcttgcgtgt tatggcagaa gcgcctacaa
    75361 cagaagaagt agactactat gttgatacca tcacagatgt agttcgtgct gaaattggga
    75421 ttgactaaat cctagaaaac tagatgaaaa taaaaaatta tggtacaata gcttataata
    75481 ttgtagccga tggagaaaga catgaatctt aaacgtgaac aagaatttgt tagtcagtat
    75541 cattttgatg cgcgtaattt tgaatgggaa aatgaaaatg gagctcctga aaccaaggtg
    75601 gatgtgaatt tccaattgct ccaacatgac caagaaaatc aagtgacttc cttgattgtc
    75661 atcttgagct ttatgattgt atttgataag tttgtcatta gtggaacaat ctcacaagta
    75721 aaccatatcg atggccgtat tgtcaatgaa ccaagtgaat tgaaccaaga agaggtggaa
    75781 accttggctc gtccatgttt gaacatgctc aatcgtttga cttacgaagt gactgaaatt
    75841 gcattagact taccaggaat taatttggag ttctaatatg aaattagctg ttttcacaga
    75901 ttcctctgct tatctcagtg aagagacctt gcaaagagaa gacttgtttg tcttggatat
    75961 tcctgtcaat attgatggtg aggaatatgt cgaaggcatc aatctgtctg ctgaggaatt
    76021 ttaccaaaaa atggctcagg cttctgaatt gcctaagacc agtcaaccaa gtattgccaa
    76081 gttagatgag atcttaactt cgctcaaaga acaaggctat acacatgcct tggggctttt
    76141 cctatcttct ggaatttcag gtttttacca aaatatccag tatatggtcg atgactatga
    76201 gggcttaacc attgctttcc cagacacttt gattacaagt gctcccctag gcatcatggt
    76261 tgaaagcgtc tttaattggc gtgatcaggg cgatgatttt gccagcattc aggataagct
    76321 agccattcaa atcagccgta cgtcagcctt tatcatggta gatgacttgg atcatttggt
    76381 aaaaggtgga cgcctttcaa atggggctgc cattttgggc aatttgctta gcattaagcc
    76441 aatcctttat tttaacgatc aaggtgtgat tgaagtttac gaaaaagttc gtactgaaaa
    76501 gaaggccacc aagcgcttaa ttgaaattat caaggaaaca acggcttcag gtcaataccg
    76561 ggtcattgtc attcatggga atgctcctga aaaggctgaa gaattgcgtc agcacttgct
    76621 tgattttggc ttgggttcgg atgtttcact tgctacattt ggtagtgtca ttggaacgca
    76681 cctaggagca ggaagtattg ctctgggtta tattccagtg atttagttgg cgcttctagg
    76741 ctagttaaga tgccttgtat cttagaaatt gaacacggac tacctgcctc ttgaaaaaag
    76801 atgcctgtct tgcctttcgt ggaaagtcag tgccattccc tatttttcag aggcagctaa
    76861 ggtcctttgt atcttgataa ttgaacacgc ctggaaccct gtgtgaaaaa gatagttctt
    76921 ccaagaagta gacacttctt gattggaatt cctattttca ctttgtgttc ttacggactt
    76981 tgtatcttag acaggagtag agatgagtat tcgagtaatt attgccggtt ttaagggaaa
    77041 gatgggccag gctgcttgtc agatggtatt gactgatcca gacttggact tggtagcagt
    77101 tttggatcct tttgagtctg agtcagaatg gcagggtatt cctgttttca aggataaggc
    77161 tgatttagct ggttttgaag cggatgtctg ggtagatttt actactccag ctgttgccta
    77221 cgaaaataca cgttttgctc ttgaaaatgg ctttgctcca gtagttggaa cgactggttt
    77281 cacgagtgaa gaaattgcag agctaaaaga attttctcgt gcccaagact tgggtggcct
    77341 gattgcccct aactttgcct tgggtgctgt cttactcatg caatttgcga cgcaggctgc
    77401 caaatatttc ccaaatgtgg agattattga gctccatcat gacaagaaaa aggatgctcc
    77461 gagtggaaca gccattaaaa cagctgagtt gatggcagag gttcgagagt ccattcagca
    77521 aggcgcagca gatgaggaag agctgattgc tggtgctcgt ggtgctgact ttgatggtat
    77581 gcacatccac tcagttcgtt tgccaggttt ggtagcccat caggaagtca tctttggcaa
    77641 tcagggagaa gggttgaccc tccgtcatga ctcctatgat cgcatctcct tcatgacagg
    77701 agtcaatttg ggaattaaag aagttgtcaa gcgtcatgag cttgtctatg gattagaaca
    77761 cttattatga gattaacgca aatgccttct gaatttcaga aggctttacc agtattagaa
    77821 aaaattaaag aagcaggctt tgaggcttat tttgttgggg gctctgttcg agatgccctt
    77881 ctccataacc ctatccacga tgtggatatt gcgacgtctt cttatccaga agagaccaag
    77941 cagatttttc cgcgaacagc cgatatcgga atcgagcatg gaaccgtctt ggtcttagat
    78001 ggggatgagg agtatgaggt aacaaccttt cggacagagg atgtctatgt ggactatcgc
    78061 agacccagtg cggtttcctt tgtgcgctcg ctagaagaag acctcaaacg ccgtgatttc
    78121 acagtcaacg cctttgcctt ggatgagaca ggagaaatcg ttgacttgtt ccatggttta
    78181 gaagatttgg aaaagcaagt cttgcgagca gttggagtgg ctagtgagcg tttcaacgaa
    78241 gatgctttac ggattatgcg tggtttccgt tttcaggcta gtcttggttt tgcacttgaa
    78301 ccagaaacat ttaaagctat gaagaccttg acgccgcttt tggagaacat ttctgtagag
    78361 cgtaccttcg tcgagtttga taaactcttg ctggctccat tttggagaag gggcttggct
    78421 tccatgattg agagtcaagc ttatgactat ctccctgata tggcatctag ccaggacaag
    78481 ctcaacagac tgtttgattt ggagactgat tttacttttg aatcctctga acaagcctgg
    78541 gcggctttac tatgggcttt ggagattgaa aatgcgcagt catttttgaa atcttggaag
    78601 acctcacgcc agtttgccaa gcaagttcag gatttgctga ttattttggc tctgcgtgaa
    78661 aatggagaat tgagcaagcg agattgttat cgctttgaca tagatttgct tttacaggct
    78721 gaaaatcttc gtcaagctca aggaaaagaa gtcaacccac aagccatcac agaaaaatac
    78781 caaagcttga ctatccatga caagaaagag attcagatta atggcggtat tttgatcaag
    78841 gaatatggct atcagccagg cccagacttg ggagagattt taacagagat tgagtttgcc
    78901 attgtcgatg gagaattgga gaataatcgt gaagccatcc atgcttacct gagggagaaa
    78961 aaatgagtga ttttatcgtt gaaaaactaa gtaaatccgt tggtgacaag accgttttta
    79021 gggatatttc ctttattatc catgacttag acagaattgg tttaatcggt gtcaatggga
    79081 ctggcaagac cacccttttg gacgtccttt ctggtgtttc tggatttgat ggggatgtca
    79141 gtcctttttc agctaaaaat gattaccaga ttggttactt gactcaggat cctgattttg
    79201 atgatagaaa gacagttttg gatacggttc tatctagtga actcaaggaa atccagctca
    79261 ttcgtgagta tgaattgatt atgctcgact atagtgagga caagcaggcg cgtttggaac
    79321 gtgtcatggc agagatggac tctctccaag cttgggaaat cgaaagtcag gtcaagaccg
    79381 ttcttagcaa attgggcatt caagacttat ctactcctgt tggggaattg tcaggtggtc
    79441 tgagaagacg ggtacagttg gcacaagtct tacttggcaa ccacgacctc ttgcttttgg
    79501 atgagccgac caaccatctg gatattgcga ttattgagtg gctgaccctc tttttgaaaa
    79561 attctaagaa gaccgtcctt tttatcactc acgatcgtta tttcttagac gctttgtcaa
    79621 cacggatttt cgagttggat cgtgcaggct tgaccgagta ccagggaaat taccaggact
    79681 atgttcgcct aaaggcggaa caggatgagc gcgacgcggc tcttcttcac aaaaaagaac
    79741 aactctacaa acaagaattg gcctggatgc gcagacaacc gcaggcgcgt gcgaccaagc
    79801 agcaggcccg tatcaatcga ttccatgatc tgaaaaagga agtttcaggc agtagtgctg
    79861 agacagactt gaccatgaac tttgaaacca gtcggattgg gaagaaagtc atcgagtttc
    79921 aggctgtttc ctttgcctat gaaaacaagc ctattttgca agattttaat ctcttggtgc
    79981 aggccaaaga ccgtatcgga atcgttgggg acaatggtgt tggaaaatca accctgctca
    80041 acttgattgc aggaagtctt gagccaacta aaggacaagt tgtgattggg gaaactgttc
    80101 gcatcgccta tttctctcag caaattgagg gtttggatga aagcaagaga gttatcaatt
    80161 acctgcagga agtggcagaa gaggtcaaga ccagtggcgg ttctacgact tcgattgcag
    80221 agttgctgga gcagttcctt ttcccacgtt cgacgcatgg aaccttgatt gagaaattgt
    80281 cagggggtga gaaaaaacgt ctttatctcc tcaaactgct tttggaaaaa ccaaatgttc
    80341 ttcttttaga cgagccaacc aatgacctag atattgcaac tttgacagtc ttagagaatt
    80401 tcttgcaagg ttttgcaggt cccgttttaa cagtcagtca cgaccgctat ttcttggata
    80461 aggtagcgac caagattctc gcttttgagg atggcaagat tcgtcctttc tttggtcatt
    80521 acaccgacta tcttgatgaa aaagcttttg aaacagatat ggccaatcaa gtgcaaaagg
    80581 tcgaaaagga aaaagtggtc aaggttcgag aagacaagaa acgcatgacc taccaagaaa
    80641 agcaggagtg ggcaagtatt gaaggtgata ttgaaacctt ggaaaaacgt atcgctgcta
    80701 ttgaagagga aatgcaggct aacggctctg actttggtaa gctggctact ctccaaaaag
    80761 aattggatga gaaaaatgaa gcactccttg aaaaatacga acgctatgag tatctcagtg
    80821 aatttgatag ttaagactat tcgaaaatca aagtgcaaac tatgtcggct tcacattgcc
    80881 gactcaagta cagcctgtga ccggcttcct aatttgcact ttgattttta ttgagtataa
    80941 acgaatagaa aaatcccgtc tcatgaaagg atttctctat tcttttttgg tttcttgatg
    81001 aaagatattt tgccaggttt cgtggcgacg ccagatactg gtatggatga taccatctaa
    81061 ctcatagcag ataagtttgg ttttttgact gatggaagta atttgaatgt ccttgatagc
    81121 agaatttaac tcttttttgg tcttataagc ctctttatcc atctgctctc catcttggcg
    81181 aatatagaca aaatcatcag tcaagagttc ttctagttgg tttccttggt cgatcaattg
    81241 ttcacgcata agcaattttt tatagacatt gtctaaaatt tcatcctcag ggataggtgc
    81301 tggttcgata tggacatcgg tatcaaagac gccaaaacgc tcctccagca tagactcgac
    81361 ctgatccgcg atttcatggc tttcaaaaac agacaagtca ggattcatct ctagtgtaat
    81421 atccaggtag atgttgctac cgtaggtgcg acctctttgc gatttgacct tgctgatttt
    81481 gggaatttcc atgatagcct tttggtagtc ctcgagcagg cggtcgtcaa agccatctga
    81541 aagactaaag gaagactcga tgaagatatc ataggcagtc ttcaagataa agaaagtgat
    81601 gatgatagca accagtttat ccacaatcgg ataattgaaa ctactagcta ggatggcaat
    81661 ggcggttcca agtgaggtaa cagcgtcaga aagattgtcc ttagcagctg ccttcagcgc
    81721 cttggagttg gatttcttac tgaggcgagt attgtagaga tagaccacaa acataatcgc
    81781 tgcagaaatg attcctagag ttgcaccaag aggatcaatg accgtttctt cccgactgag
    81841 aatcttttga atggtatctc ttagaacatc gaaaccgaca tagaacatga tgatagaagt
    81901 gatcaagctt gccaaatctt caatcttcca atgaccaaaa cggtggtcac ggtctgcagg
    81961 ctggcgcgcc atccgaatcc cgattaagag ggccacattt ccaatgatgt ccgatacgtt
    82021 attaaaacca tcggccacca aactggatga atgaaggaga tgaccagttg ctaatttggc
    82081 tgcagacaag atcaaatagg tcgaaatact gataatggct ccacgctcag ctaacttgag
    82141 atttgagata gattgcttca ttcaacttcc tttctagtca catagcattc taccattata
    82201 ctggttttca aggaaaaatt caaataaggc agtttttact ctttgaaaac tccccaaaat
    82261 ttggtataat ggtactactc aagggagtag ctggcagaaa cctgtgatag tgtcgtcatt
    82321 ccgaatttta tgctgaaaag tatgctttcc ggccctatct taaacagcga gacttgttat
    82381 gattaacagg tctctttttg tttgtcgtga aaagatatga cagaaagaga gtctgttttg
    82441 cacacaatgt caaggaggag acacatgtca aaagaacaaa aacgccaagc gttttatact
    82501 cagagccctg aagaggtctt gcaggctgtg gatgcgaccg agcaaggttt gtcatcaagt
    82561 gaggcggaaa agcgccttgc cgaatttggg cacaatgaac tcgaagaagg cgagaaacga
    82621 tcaatcttgg tcaaattcat cgagcaattt aaggatttga tgattatcat cctagttgcg
    82681 gcagcaatct tgtcagtcgt gacttctggt ggggaagata tcgcagatgc cattatcatc
    82741 ctagctgtgg ttatcatcaa cgctgccttt ggtgtttacc aagaaggaaa agctgaagaa
    82801 gctattgaag ccctcaaatc catgtctagt ccagttgccc gcgttcttcg tgatggacac
    82861 atggcagaga ttgactctaa agaattggta ccaggcgata tcgttgccct tgaagcaggt
    82921 gacgtggtac cagcggacct acgtttgata gaagccaact ctcttaaaat tgaagaagca
    82981 gccttgacag gtgaatctgt accagtcgaa aaagacttgt cagtcgagct tgcgacagat
    83041 gctggtattg gtgaccgtgt caacatggcc ttccaaaact caaacgtaac ctatggtcgt
    83101 gggatgggtg ttgttgtcaa tacaggtatg tacactgaag ttggtcatat tgctggtatg
    83161 cttcaagatg cggatgagac tgatacacca ctcaaacaaa acttgaacaa cctttctaag
    83221 gtcttgacct atgctatctt ggtcattgcc cttgttactt ttgtagtggg tgtcttcatt
    83281 caagggaaaa atccacttgg tgagttgttg acttctgttg cccttgccgt tgcagccatt
    83341 ccagaaggac ttcctgctat cgttaccatc gttctttctc ttggtactca agttttggcc
    83401 aaacgacatt ccatcgttcg taagttgcca gcagttgaaa cacttggttc aactgaaatc
    83461 atcgcttctg ataagactgg tacgctgact atgaacaaga tgacagtcga aaaagtcttc
    83521 tacgatgcgg ttctacatga ctcagctgat gatattgaac taggtcttga aatgccacta
    83581 cttcgttcag ttgtcttggc caatgatacg aaaatcgatg tggaaggtaa cttgattggt
    83641 gacccaaccg aaacagcctt tatccaatat gccttggaca agggctatga tgtcaaaggt
    83701 ttcttagaga aatatcctcg tgtagctgaa ttgccatttg actctgaccg taagctcatg
    83761 tcaacagttc acccattgcc agatggtcgt ttccttgtag cagtcaaggg tgcgccagac
    83821 caactcttaa aacgttgtct tcttcgtgat aaggctgggg atattgctcc gattgatgag
    83881 aaggttacaa atctcattca tacaaacaat tctgaaatgg ctcatcaagc cttgcgtgtc
    83941 cttgcaggtg cttataagat tatcgatagt attccagaaa atctcacttc tgaagagctt
    84001 gaaaatgatt taatttttac tggtttgatt gggatgattg accctgaacg tcctgaagcc
    84061 gctgaggctg ttcgtgtggc taaggaagcg ggaatccgtc caattatgat tacaggtgac
    84121 caccaagaca cagcggaagc cattgccaaa cgtttgggaa tcattgacgc aaacgataca
    84181 gaaggtcacg ttttaactgg tgctgaactc aatgaactgt cagatgaaga atttgaaaaa
    84241 gtcgttggtc aatactctgt ttatgcccgt gtgtctccag aacacaaggt tcgtatcgtc
    84301 aaggcttggc aaaaacaagg taaagtcgtt gccatgacag gtgacggtgt caatgacgcg
    84361 ccagctctga aaacagccga tatcggtatc ggtatgggaa tcactggtac agaggtttct
    84421 aagggggctt ctgacatgat tcttgcagat gataactttg cgactattat cgtcgcagtg
    84481 gaagaaggac gtaaggtctt ctcaaacatt caaaagacta ttcagtacct actttctgct
    84541 aatactgctg aagtattaac catcttccta tcaaccttgt ttggttggga tgtcttgcag
    84601 ccggttcatc ttttgtggat caacttggta acggatacct tcccagctat cgctcttggt
    84661 gttgaacccg cggagcctgg tgtcatgaat cataaaccac gtggacgcaa ggcaagcttc
    84721 ttctcaggtg gtgttttgag ttctatcatt tatcaaggtg tactccaagc agctcttgtt
    84781 atgagtgttt atggccttgc gattgcttac ccagttcatg tgggtgacaa tcatgctatt
    84841 catgcagatg ccctaacgat ggcctttgca acccttggtt tgattcagct cttccatgcc
    84901 tacaatgtca agtctgtcta ccaatccatc ttgacagttg gcccattcaa gtctaagacc
    84961 tttaactggt ccatcttggt atcctttatc cttctcatgg caacaatcgt tgtagaaccg
    85021 cttgaaggaa tcttccacgt aaccaaacta gacttgtcac aatggggaat tgttatggct
    85081 ggaagcttct caatgattat catcgtcgaa atcgttaagt ttattcaacg caaactcggt
    85141 tttgacaaga atgcgattta agggaggttt cggatgtcag catatcaatt accgaccgta
    85201 tggcaggatg aagctagtaa tcaaggagct tttacggggc taaacagaca aacagcaggt
    85261 gcccgtttcg aacaaaactt gccaaaagga gaacaagctt ttcagcttta ttcactggga
    85321 acaccaaatg gtgtgaaggt tactatctta ttggaagaat tactagaagc tggttttaag
    85381 gaagcggctt acgacttgta taagattgct atcatggatg gggatcaatt cggatcagac
    85441 tttgtgaagc tcaatccaaa ttccaagatt ccagccttat tggaccagtc aggtactgaa
    85501 gatgtaagag tctttgagtc tgctcatatt cttctttacc ttgctgagaa atttggagcc
    85561 tttttaccaa gtaatcctgt ggaaaaggta gaagttttga attggctatt ctggcaagca
    85621 ggtgcagcac cttttctagg tgggggattt ggacatttct tcaattatgc tcctgaaaaa
    85681 ttggaatatc ctattaaccg ttttacgatg gaagtgaaac gccagttgga tttattggat
    85741 aaggaattgg ctcagaaacc ttatattgca ggcaatgact atacgattgc agatattgct
    85801 atctggtctt ggtatggaca gttagttcaa gaaaatcttt accaaggttc tgcaaaattc
    85861 ttggatgcct caagttatca aaatctagta aaatgggcag aaaaaattgc caatcgtcca
    85921 gctgttaagc gtggcttgga agtaacttat acagaaatta aatagcaaaa aagtcatctt
    85981 cggatggctt tttgctacag ttgagggaaa gggtttgcag ttatcggctt ttgtgctata
    86041 attgctataa tatagtaaaa agcaagagga gtgtgaggaa gtggaaaaga aaattgtgaa
    86101 ggataactta tttttatctc aagtgtctca gccggcaagt caggaggacc tttatcttgc
    86161 cagagatttg caggatacac tcttagcaaa tcgtgatacc tgtgttggtc tagctgccaa
    86221 tatgattggg gtgcagaagc gcgtgattat ctttaatctt ggcttggttc ccgtggtcat
    86281 gtttaaccca gtgcttctgt cctttgaagg atcttatgag gcagaagaag gctgtttgtc
    86341 cttggtaggt gtgagatcaa ctaagcgtta tgaaaccata aggcttgcct atcgtgacag
    86401 caagtggcag gaacagacca ttaccttgac aggcttccca gctcagattt gccagcatga
    86461 gctggatcac ttggaaggac gaatcattta ggaggaaagc aaatgaaacg aatagtcttt
    86521 gaacttattt ttatcgcaac gacctggtat atctttttac cgccccttaa cctgaccagc
    86581 tgggaatttc tcttcttcct ctgtgggcat ttgttagttg tggcaatctt atttggcttt
    86641 ggcaagggga taaaccttgt caaaacggtt catgtgcgcc acggtaaggc ggaagctgcc
    86701 ttaaatcttg agggtttcaa aatcaatcgg ttagggaaaa ttctgttagc ttcgattgga
    86761 ggaattcttc tcttggcagc tttggtttcc ttggtaactt ccagcatgtt tcaggctaaa
    86821 aattatgcca atgtagtcac ggttacggaa aaagacttta ctgaatttcc taggagtgac
    86881 accagtaagg ttcctatcct agatagaagt actgctgaaa aaattggaga ccgctacttg
    86941 ggttccctaa ccgataaggt gtcgcaatac gtagcggcag atacctatac ccaattgaca
    87001 attgatggga aaccttatcg ggtcacacca ctagaatatg cagaccctat caaatggttt
    87061 aacaatcaag ccaagggaat cggtgagtat atcaaggtgg acatggtaac tggaaatgcg
    87121 gatttggtgg acttgaagac accaatcaag tattcagact cggagtattt taaccgtgat
    87181 gtcaaacgtc acctgcgctt gaagtacccg accaaaatct ttaaaactcc atcttttgag
    87241 gtggacgatg agggcaatcc tttctatgta gcaacggttt accaaaagca atttggactt
    87301 gctgttcctc gtcctgcttc agtcattatc ttggatgcta caaatggaga aaccaaggaa
    87361 tacagcttat cagatgttcc agaatgggtg gacaggatct atccagcaga ggaaaccatt
    87421 gagcaaatta actacaacgg caagtacaag gacggtttct tgaatgccat gatttccaag
    87481 aaaaacgtga cccagactac caagggctat aattacttgt ctatcggtaa tgacatctat
    87541 ctctacacag gtgtgacgtc ggctaatgcg gatgagagta atcttggttt catccttgaa
    87601 aatatgcgaa caggagaaat cactaagtat agcttggctt ctgcgacaga agaatcagcc
    87661 cgtgaatcag cagaaggtgc tgttcaggag aaatcctaca aagcaacctt cccaatcctc
    87721 atcaacctca atgacaagcc tctctacatc atgggcttga aggacaatgc tggcttggtc
    87781 aaagagtacg ccctggtaga cgcagtcgag taccaaaatg ttatcgttgc tactacagtg
    87841 gaagagatgc tcagcaagta tgccaataaa aacgaccttg aaattgacaa tgcaacgaca
    87901 gaaagcatca atggagtagt agcagacctc aaatcagctg ttatcaaggg agacactgtc
    87961 tacttcttta aagttgatgg caagatatac aaggtcaagg cttcagtatc cgatgacctt
    88021 ccttaccttg aaaatggtaa aaccttcgaa ggtcaagtag gaaaagacaa ttatctcaag
    88081 acctttaagc tacggtaaaa ataggttttt ttcagaaagt atatgttata ataaggtaaa
    88141 ttaagcctaa tggaggacaa agaaatgggt ttttatttga tggttgcttc aatgctactc
    88201 ggactgctcg ctttgaagat aggtttttct cagttcaagg agaaaaaaga taaattctta
    88261 tctatcttaa caagtttagc tggcacagcc cttgttctcg tggctgtctg gttaggatgg
    88321 cccaaataaa tagaaaaacc tcggtcaaac cgaggttttt caaatgaatt tcttggttgt
    88381 ggctaaaaaa tatgctacac tatcaatatg aaaattttaa tcccaacagc aaaagaaatg
    88441 aacacagact tgccaagtat cgaggcaatt cctttaaaac cagaaagtca gaccgtgctt
    88501 gatgccttgg ctctctattc tgccagtcaa ttggagagtt tctacaaggt atcagctgag
    88561 aaagcggcgg aagaatttca aaatatccaa gctttgaaaa ggcaaactgc tcaacactat
    88621 ccagccttga aactttttga tgggcttatg taccgcaaca ttaagagaga taagctgacc
    88681 gaggcggaac aagattatct tgaaaatcat gtcttcatta cctcggcttt gtacggtgtt
    88741 gttccagcct tgtcacccat ggctcctcac cgtttggatt ttttgatgaa attaaaagtc
    88801 gctggtaaga ctttgaagag ccattggaag gcagtctatg atgaagctct gaagaaggaa
    88861 gaagtgattt tctctctctt gtcatcagag tttgagactg tattttctaa ggaaatcaga
    88921 gcaaagatgg tgaccttcaa attcatggag gatagaggcg gtcagctgaa gattcactca
    88981 actatctcca agaaagcgcg cggggccttt ctaacagctt taatagaaaa tcaagtacaa
    89041 actgtggggg aagcacgtcg cttgaacttt gctggatttg tttaccgaga agatttgtca
    89101 caaccacagg gattggtttt tgtaaaggaa gtatagaaat cagatatttt gtatttggca
    89161 atatgtatca tcagctgttt tagtttataa atgagaaaaa aagcgaacaa gctagtcttc
    89221 tgagtgtcag aaaagtagtc ttgttcgctt ttattatgtt atactcttcg aaaatctctt
    89281 caagccacgt cagcgtcgcc ttaccgtata tatgtcactg acttcgtcag ttctatctac
    89341 aacctcaaag cagtgctttg agcagcttgc ggctagcttc ctagtttgct ttttgatttt
    89401 tattgagtgt tagttacttg atagcttcga ccaagtcttg agcttgtttt tcaagtgagt
    89461 ttaggactgt ttcttcaaga accaattttc cgtctgccca ggcagagtca ttaacacgtg
    89521 cagcagtgaa atcaccaacg ccttgtgtac ggataaatgg caagaggtct ttgtagatag
    89581 cgaaaagttg atcgtgccct gcattggcta cagatgatac tgtgacaaac ttgtcttgaa
    89641 gggcagaaac gccacgtgta tcagacaagt caagggcacg agatagccag tcaagcaagt
    89701 ttttcactgt accagggata gagaagttgt agactggaga gaaaatccag atagcatccg
    89761 caacgagaac tgcttcacga gcggcagcta cagctggatg tgttgggact tccaaatctt
    89821 ggctgaagag agggagggct gaataatcaa ggtagctaac ttccgcttta ctagcaagtg
    89881 ctttctcagc ttcgagcgcc atttggtggt tgaaagaacc ttgacgtagt gatccgacga
    89941 taaataatac ttttttagac atgatgtgtc tcctttttct taaaatttcg agaactctct
    90001 cgttgttata aaatatatta caacaaaaca aaagaacttg caagaaattt gctcagagtt
    90061 tatttgaaaa ttgtaaaatt tcggaaactc tagtcatttg tgactgaaaa agtaagaact
    90121 gtttcacttt caaaatcggt tttgtttgaa gggagaaata gaattggttg ctcaaagcac
    90181 agctttgagg ttgcagataa agctgacgtg gtttgaagag attttcgaag agtattctta
    90241 tattcacttg taataaagct taatagatgg taaaatagac gagtgaaaaa aagacaaaac
    90301 aaagcaaaaa ataatctact gtggcagtat ggtctaggga tgacgatttt gtttgtggtt
    90361 atcagtggtt cctttctgta tatggtttct cttagcatga aaccctatca aacagctaaa
    90421 agtgaaggag aaaaattagc tcagcagtat gcaggattag agcaggtcga tcaggttgat
    90481 ttatacaatg gcttggaatc ttattacagc gttcttggtc gtaataaaca gcaagaagcg
    90541 cttgctgtcc tgattggtaa agatgatcat aagatttacg tttatcagct aaatcagggt
    90601 gtttcacaag aaaaagcaga aacggtttct aaggaaaagg gagctggcga aattgacaag
    90661 attatctttg gtcgttatca agataagcca atctgggaag tcaagtcagg atctgatttt
    90721 tatctagtag attttgaaac aggagcattg gtcaacaagg agggcctatg gaattatcca
    90781 accgtgtttt agaaatggaa gaaagtgtga ctttggctgc tggagcccgt gccaaagcac
    90841 tgaaggctga gggtagagat attttgtctc taaccttggg tgagccagat ttcactactc
    90901 ccaaaaatat ccaagatgcc gccattgcat cgattcgaga tgggcgtgct tctttttata
    90961 cagtaacctc aggtctgcca gagcttaagg cggcggtcaa tagctacttt gagcgctttt
    91021 acggctattc tgtagcgtca aatcaagtga cagtcgctgc gggagccaaa tattctctct
    91081 ataccttctt tatggctgtg gtcaatccag gtgatgaagt catcatccca accccatact
    91141 gggttagcta tggagatcag gtcaagatgg cagaaggcgt tcccgtcttt gtttctgcta
    91201 aggaagacaa tcactttaag gtgaccgtag agcagttaga agcagctcgc actgacaaga
    91261 ccaaggtttt ggtgctgaat tcgccatcta atcccacagg tatgatttac acccgtgagg
    91321 aactcttggc aattggaaac tgggctgtag aaaatgatat tctcatccta gcagatgata
    91381 tctatggccg cttggtttat aatggtcatg agttcacacc gatttctagc ctatcggaag
    91441 cgattcgcaa gcaaacagtg gtcatcaatg gtgtgtctaa aacctatgcc atgactggtt
    91501 ggcggattgg ttatgccgtt ggagaagcag acattatcgc tgccatgtcc aagattgcag
    91561 gtcaaacaac ttcgaatccg tcagcagtag cccaatatgc agcagttgag gctctatcag
    91621 gtgagcaaga tactgtagaa agcatgcgtc aggcctttga ggaacgtctt aataccatct
    91681 atcccctcct tgcagaagtg ccaggatttg aagtggtcaa accgcaaggg gccttctatc
    91741 tcttcccaaa tgtcaaaaag gccatggaga tgaaaggcta cacggatgtg acagacttta
    91801 caactgttat cttagaagaa gccgaagtgg ccttggtaac aggagctgga tttggagcac
    91861 cagaaaatgt ccgcctcagc tatgcgacag acctagacac gcttaaagaa gcagtcgaac
    91921 gcttgaaagc atttatgggt agtgagaatg attgatcatt ttgagattaa ggtaaaggat
    91981 ttacaaattt cagaaggatt ttataggagt tttctcgctc ctttggacta taaattggct
    92041 tttaagacta gttctctaat tagttttcta tccccgaaca gccctcatcc tggtggtgat
    92101 ttttggctga ctcagggaac acaagatcct gttcattttg cttttttagc agaaaataag
    92161 gaagaagttc aggcttgtta tgaggctggc ttagaggcag gtgggcgaga caatggggct
    92221 cctggttatc gaagtgagca tccgatttac tatgctgctt ttgtgattga cctggatggg
    92281 aacaatatag aggtggtttg ccataaagaa taaaaaagaa aaggaaaaat aatgacaaaa
    92341 cgtgtaacga ttattgacgt aaaagactat gttggtcagg aagtgacgat tggcgcttgg
    92401 gttgccaaca aatcaggaaa agggaaaatc gctttcttac aattgcgtga tggaacagcc
    92461 ttctttcaag gtgtggcttt taaaccaaac tttgtcgaaa aatttggtga agaagtggga
    92521 cttgagaagt ttgatgttat caaacgcttg agccaagaaa cgtctgttta tgtgacaggt
    92581 attgtcaaag aggacgaacg ttctaaattt ggctatgagt tggacatcac agacatcgaa
    92641 gtgatcggtg aatctcaaga ctacccaatc acaccaaaag aacacggaac agactttttg
    92701 atggataacc gtcacttgtg gctacgctct cgtaagcaag tagctgtgtt gcaaatccgt
    92761 aacgctatta tctatgcaac ttatgagttc tttgacaaga acggttttat gaagtttgac
    92821 agcccaattc tttcaggaaa tgcggcagaa gattctacag aactctttga aactgactac
    92881 ttcggaacgc cagcctactt gagccaatca ggtcaacttt acctagaagc aggggctatg
    92941 gctcttggtc gtgtctttga ctttggtcca gttttccgtg ctgaaaaatc aaaaacacgc
    93001 cgtcacttga ctgagttctg gatgatggat gctgagtact catacttgac acatgatgag
    93061 tcgcttgact tgcaagaagc ttatgtgaaa gctcttctac aaggtgttct tgaccgcgcg
    93121 cctcaagcct tggaaacctt ggaacgtgat acagaactct tgaaacgcta cattgcagag
    93181 ccattcaaac gtatcactta cgatcaagcc attgacctct tgcaagagca tgaaaatgat
    93241 gaagatgctg actacgagca tcttgagcat ggtgatgact ttgggtcacc acacgaaact
    93301 tggatttcaa accactttgg tgtgccaaca tttgtcatga actatccagc agccatcaag
    93361 gccttctaca tgaaaccagt tcctggaaat ccagagcgcg tgctttgtgc agacttgctt
    93421 gctccagaag gctatggaga aattatcggt gggtctatgc gtgaggaaga ttacgatgcc
    93481 cttgtcgcta agatggatga acttggcatg gatcgtacag aatatgaatt ctaccttgac
    93541 cttcgtaaat acggtacagt tccacacgga ggatttggta tcggtatcga acgtatggta
    93601 accttcgcag caggaacaaa acatatccgt gaagctattc cattcccacg tatgttgcac
    93661 cgtatcaaac cataagaaca ggaaaacgcc catgtggcgt tttttcgaat tctagtgttt
    93721 ttacttgcgt aaaaaaattt tttctagtat aatagtttat tgtgagcgaa cctcacttac
    93781 cccttgcaaa gtcttggggt cattagacca aaaggaggaa catatcaatg gctaaatacg
    93841 aaattcttta tatcattcgt ccaaacattg aagaagaagc taaaaacgct ttggtagcac
    93901 gttttgactc tattttgact gacaacggtg caactgttgt tgaatcaaaa acttgggaaa
    93961 aacgtcgtct tgcatacgaa atccaagatt tccgtgaagg actttaccac atcgttaacg
    94021 ttgaagcaaa tgacgatgca gctcttaaag agtttgaccg tctttcaaaa atcaacgctg
    94081 acattcttcg tcacatgatc gtcaaaattg acgcgtaaga aggtaaacta tgattaacaa
    94141 tgttgtactt gtagggcgta tgacacgtga cgctgagttg cgttataccc catcaaatgt
    94201 agcagttgcg acttttactc ttgcagtaaa ccgtacattt aagagtcaaa atggtgaacg
    94261 tgaggctgat tttatcaatg tcgttatgtg gcgccaacag gctgaaaatc ttgctaactg
    94321 ggctaaaaaa ggctcactta tcggggtgac aggtcgtatc cagactcgta gttacgataa
    94381 ccagcaagga caacgtgtct acgtgacaga ggtcgtggct gagaatttcc aaatgttgga
    94441 aagccgtagt gtgcgtgagg gccacacagg tggagcttac tctgcaccaa ctgcaaacta
    94501 ttcagcacct acaaattcag taccagactt ttcacgtaat gaaaatccat ttggagcaac
    94561 aaacccattg gatatttcag atgatgattt accattctaa tggacaacta aacttataaa
    94621 ggagaaaaaa catggctcaa caacgtcgtg gcggattcaa acgccgtaaa aaagttgatt
    94681 acatcgcagc aaacaaaatt gaatatgttg attacaaaga tactgagctt cttagccgtt
    94741 tcgtttcaga acgtgggaaa atccttcctc gtcgtgtaac aggaacttca gctaaaaacc
    94801 aacgtaaagt aacaacagct atcaaacgcg ctcgcgtaat ggctttgatg cctttcgtaa
    94861 acgaagatta aagaaaagac ccggttgggt ctctttttca tgagcttgaa aacaagaaag
    94921 cgaattaaga ccccaacggg tcttttttca caagctttga aatgagagag cgagttaggc
    94981 tcagtggctc cctttttacg agtttgaaaa caagagaaca cattaaaagc acgatggagc
    95041 tttttcataa atatgtcttt tttctcatcc aagaaattaa aataaaaatg ataaactttt
    95101 tgaaaatagg ggatttgcct actttatgat ataatggaaa gagttagatt gaaagaggta
    95161 gtgagatgga cgcgaaatta agatacaagg caaagaagat caagattgtc ttttttgata
    95221 ttgatgatac attgcggaat tcaaagacag ggtttattcc aactacaatt cccactgttt
    95281 ttaaacagtt gcgtgaaaaa ggaattttaa caggaatcgc ctctggacgt ggcatttttg
    95341 gtgttgttcc agagattcgt gatctcaagc ctgacttttt tgtaactttg aatggagctt
    95401 atatcgaaga taaaaaaggt caggtcattt atcagcatca gattgaaaag tcagatgttg
    95461 aggagtatat ctcttgggct aagcaagaag gaattgaata tggcttggtt gggagtcatg
    95521 atgccaagtt gtcgactcgc accgatatga tgagtgaagc tatcaatcca atttatcccg
    95581 acttagatgt agatcccgat ttccatgaaa aagaagatat ctatcagatg tggacttttg
    95641 aagataaggg agatgacttg cacttgcctg acagtctctc agacaaactt cgcatggttc
    95701 gttggcatca acattcgtct gatattgtgc cgatttcagg ctccaaagcg acgggggtgg
    95761 aaaaggttgt ggaacacctt ggcttgaaac cagagaaggt catggttttt ggagatggtc
    95821 tcaacgactt ggaactcttt gattatgctg gaatcagcgt tgccatggga atttctcatg
    95881 ataaaatcaa agaaaaagca gattatatta caaaaacatt agaagaagat ggcatttttg
    95941 atgccttaga agtatttggt atggtagaaa aagaattgca ttttccacaa gtagacattg
    96001 aaacagtaga aggtcctctt gcgactatta agaccaatca cggagactta cgtatcaagc
    96061 ttttccctga acatgctcct aaaacagtgg ctaactttgt atctctttca aaagatggct
    96121 actatgatgg tgtcattttc caccgtatta tcaaggactt tatgatccaa ggtggagacc
    96181 caactggaac tggtatgggt ggcgagtcaa tctacggcga atcttttgag gatgaattct
    96241 cagaagagct ttacaatatc cgtggtgctc tttccatggc aaatgctggt ccaaatacca
    96301 acggcagcca gttctttatc gtgcaaaacc aacacctacc ttattcgaag aaagaaatta
    96361 ctcgtggtgg ttggccagaa ccgattgcag aaatctatgc caatcaaggt gggacacctc
    96421 acctagaccg ccgtcacacg gtttttggtc agttagctga tgaagcatct tacgctgtct
    96481 tggatgccat tgctgctgtt gagacaggag ctatggacaa gccagttgaa gatgttgtaa
    96541 ttgaaactat tgaaatcgag gactaagatg aaaatcggtg ataagctaaa ggggcgtatt
    96601 acagggattc agccctacgg tgcctttgtt gagttagaga cgggtgatac ggggctgatt
    96661 cacatttcag aaattcggac aggatttatt gaaaatattc atgaaacctt gaaagtcgat
    96721 gaagaggttc aagttcaggt agtggattta gatgaattta cggggaaagc cagtctttct
    96781 atccgcactt tggaggaaga aaagtaccag tttcctagac ggagacgctt ttcaagcgac
    96841 cgctttaact acggttttgc tccctttcga cgaatgctac caatctggac tggagaagcc
    96901 ctgcaccatt taaaaaagaa gaagtagttt agagttttat attttttgta atgttaatat
    96961 gaatttgcta taataggacc atggaagaag aacaattatt aaaatcagga gagcgcatta
    97021 accagctctt ttcgacagat atcaaaatca ttcaaaatag agaggttttt agctattcgg
    97081 tggatagtgt tctcttatca cgatttccac gttttcctaa gaaggggttg attgtggatt
    97141 tctgtgctgg gaatggagca gtggggcttt ttgctagcac tcgtactcaa gcacagatat
    97201 tgtctgttga gattcaggag cgtttggcgg atatggctga acgctctgtc cgtttgaatg
    97261 gattagagga gcaaatgcag gtcatctgcg atgatttgaa aaatatgcct gctcacattc
    97321 aggggagtaa ggtggatatg attttgtgta atccacccta tttcaaggtg aatccttatt
    97381 ctaatctgaa cgagagtgaa cattatctct tggctcgaca cgaaatcacg actaatttgg
    97441 aagaaatctg tcgtagtgcc cagagtattc tcaagtctaa tgggcgtttg gccatggttc
    97501 atcgtcctga tcgacttctg gatattttgg atacgttaaa acgacataat ctagccccta
    97561 agcgcctgca gtttgtttat ccaaaaagag aaaaggaagc caatatgctt ttgattgagg
    97621 cgatcaagga tggctcaaca agtggcttta aggtcttacc tcctttgatt gtccacaatg
    97681 atgatggctc ttatacgccc gaaatcgaag agatttatta tggatcataa ggcttatatg
    97741 tacgttctgg agtgtcgtga tggatcctac tatataggct atacgactga tatgagaaga
    97801 cgcctcgcta tccacaatag tgggaaggga gccaaatata cacgagcacg cttgccagtc
    97861 aaacttatct atgctcaagg ttttgccagt aaggaagaag ccatgtcggc tgaagctctt
    97921 ctcaagcgta agaagaggcc acagaaggaa gaatttttat ctgaaaatca agatagaaat
    97981 ttactcagtt attttgaaga atcgtgggga gtcctttgac tcctcttacc tttgtcaaaa
    98041 agcgaaaaaa atgctacaat aaagaaaata aacaaaatga ggtattatca tgtccaagat
    98101 tctagtattt ggtcaccaaa atccagactc agatgccatc ggatcatctg tagcttttgc
    98161 ctaccttgca aaagaagctt acggtttgga tacggaagct gttgcccttg gaactccaaa
    98221 tgaagaaaca gcctttgtct tgaactattt tggtgtggaa gcaccacgtg ttatcacttc
    98281 tgccaaagca gagggggcag agcaagttat cttgactgac cacaatgaat tccaacaatc
    98341 tgtatcagat atcgctgaag tagaagttta cggtgttgta gaccaccacc gtgtggctaa
    98401 ctttgaaact gcaagcccac tttacatgcg tttggagcca gttggatcag cgtcttcaat
    98461 cgtttaccgt atgttcaaag aacatggtgt agctgtgcct aaagagattg caggtttgat
    98521 gctttcaggt ttgatttcag atacccttct tttgaaatca ccaacaacac acccaacaga
    98581 taaaatcatt gctcctgaat tggctgaatt ggctggtgtg aacttggaag aatatggttt
    98641 ggcaatgttg aaagctggta ccaacttggc tagcaaatct gctgaagaat tgattgatat
    98701 cgatgctaag acttttgaac tcaacggaaa taatgtccgt gttgcccaag tgaacacagt
    98761 tgacatcgct gaagttttgg aacgccaagc agaaattgaa gctgcaatgc aagctgccaa
    98821 cgaatcaaac ggctactctg actttgtctt gatgattaca gatatcgtca actcaaactc
    98881 agaaatcttg gctcttggtg ccaatatgga caaggtcgaa gcggctttca acttcaaact
    98941 tgaaaacaat catgccttcc ttgctggtgc cgtttcacgt aagaaacaag tggtacctca
    99001 attgactgaa agctttaatg cgtaagattt tgggtgtcag ctcaaaatcg gaaagtctag
    99061 tttgccttat atcgaaagga gtttcggctc cttttttcta ggagtgaagt atgttagaaa
    99121 atggcgattt gatttttgtg agagatgggt cagacatggg acaggccatc cagacttcca
    99181 caggtaacta tagccatgtt gccatttatt tggatgggat gatttatcat gctagtggac
    99241 aggctggtgt tgtctgtcaa gaaccggcag acttctttga gtccaatcat ttatacgacc
    99301 tctatgttta cccagaaatg gatatccagt cggtgaagga aagagcttgc aaacatcttg
    99361 gagcacccta caatgcttct ttctatccag atgcacctgg tttctactgc tcccagtata
    99421 tagcagaaat cctacctatt tttgaaacta ttcctatgaa atttggagat ggggagcagg
    99481 agattagtga tttttggagg gagtattaca tagaactagg tctgcctgtt cctctgaacc
    99541 aagctggtac caatcctagt cagttggcag catcgcctct gttacaatgt aaagaaagga
    99601 atcttcatga ttcagatttt taatccatct cgtttgacga gacagccatt tttggagaat
    99661 tgatccgcta tctggaccag tatgaggatg tgattctacg ggaaattaag gctcaatttc
    99721 cagatgttgc agttgataaa ctcatggaag agtatataaa ggcaggcttg attctacgtg
    99781 aaaataagcg ctattacctc aattttccta cgcttgaatc acttgatagt cttgaactgg
    99841 atcaagagat ttttgtcaga gaagctagtc cggtctatca agccttgttg gagcagagtt
    99901 ttgagacgga attgcgcaat caaatcaatg cagctatttt agttgaaaag acggactttg
    99961 cgcgcattaa aatgactctg tccaattatt tttacaaggt caaacagcag tatcctttga
   100021 cagaaaaaca gcaggagctc tatgacattt taggagatgt taatcctgag tatgcactca
   100081 agtatatgac ggcttttttg ttgaaatttc tcaaaaaaga ccagcttatg cagaaatgcc
   100141 gtgatatctt tgtggacagt ttggttgtct taggctatat tgtgcaaaat gaagatggaa
   100201 agtatgagtt ggctatcgat tttgataagg agagattaac tttctactta gcgtgatttc
   100261 ttgtttctga gtacattgtt tgactttcct tagtattcgg tataaactat atgtaaccgg
   100321 taacacatat cggaataaac taaaggagac aatcatatgt cacttgaaaa caaattggaa
   100381 caagcaacag gcgctgtcaa agaaggtttt ggtaaagtta ctggagacag caagacagaa
   100441 cttgaaggag ctgttgaaaa aacagttgct aaggcaaaag acgttgtaga agacgcaaaa
   100501 ggtgctgtag aaggtgccgt tgaaggtttg aaaaacgttt ttactaaaga ataggaaaaa
   100561 atcaagggtt tcattttccc ttgatttttt ctattcttat aaataatttt ctgcgacggc
   100621 tgtatctcct gggtaggatt ctttcttgcc ctggatgatt tggtaacaat cggctccctt
   100681 acccgcaata ataactgcat ctaattcgtg atttgtgata gccattgccg ccttgatggc
   100741 ttcttggcga tccgcaatct tctcaacagg atgattgatg tagctactaa tttcatctgc
   100801 aatggccatt gggtcttcat agttagggtc atcagcagtc agaaagactt gaatctcagg
   100861 gtgttgattg aggaggaggc caaagtcctt acgacgactt tctcccttgt ttcctgttga
   100921 tcccagaacc agagcaatct ttccggtttg atgagtttca accacattga tgagtttttt
   100981 cagactatcc ccattgtggg catagtcgat gaagaccttg gctccatttt tctgagtgag
   101041 gacttccata cgaccaggaa cgcgggttgc agcgatgcct tttttgatgt cctcaagact
   101101 tgctccgaga cggagacaag caagtccagc agcaactgca ttttcttggt tgaagttgcc
   101161 aatgagttgg atatcataat ctccagcgag tttacccgta gctgaaaagc taaaggcttt
   101221 ggaattctcg atttggttat caaattggct accatagaaa tcatggtctt gatcttcaac
   101281 ctgttctttc aagactgaga agtggtccat gtcactgtta atgatgactg ctcggctatt
   101341 ttccatcaag agacgcttgt ggtagaaata gtcttcaaag ctagggtgtt caatcgggcc
   101401 gatatggtct gggctgatat tgaggaaaac tcccacatca aaggttagac catagacacg
   101461 tctgaccaga taggattgac tggagacttc catgatgagg tgggtacggt cattttgcac
   101521 agcctgattc atcatgtcaa agaggtcaat actctcaggg gttgtcaacg ctgacttaaa
   101581 gaaagtctcg ccatcaagag ttgtgttcat ggtcgacaac atagcaggtc gatgcccttg
   101641 agataagatg ttataggcga aataggctgc tgttgtctta cccttagtac cagtaaaggc
   101701 aaggagtttg agtttttcct gtggattacc atagaactcc atggcaatca aactcatggc
   101761 tttctttata tcgttcacaa tgatgacagg gataccgact tcgtagtcct tttcagctac
   101821 ataccaagct aagccttgtg ttatagcaga aagaaggtat tcttttttaa aggcagcgcc
   101881 ttttgcaaaa aaaagagtgt cttctgttac ttttcggcta tcgtagctga tgctatcaaa
   101941 aacaactttg ctgtagttgt agtggtaatg accttggtca ataatttcgc gaaaaaggcc
   102001 atctttcttt aaaatatcta atacagtttc aatttttatc atactttcta ttgtaaaccg
   102061 aaagtcgcaa atttacaagt aacaaggaaa agtttataat ggaagataag gagtttttcc
   102121 tagttatcaa aattgaatga ggaatctatg tcgcacgaaa acaatcacca gcaggcccag
   102181 atgttacggg ggactgcttg gctaacggct agtaacttta tcagtcgcct actcggggct
   102241 gtttacatta tcccttggta catctggatg ggggcttatg cagctaaggc aaatggtctc
   102301 tttaccatgg gttacaatat ctatgcttgg ttcttgttgg tttcaacagc ggggattcca
   102361 gttgcggtgg ccaagcaagt tgccaagtat aataccatgc gagaagaaga ggatagcttt
   102421 gccctgattc ggagcttctt aggctttatg acaggactag gcctggtttt tgctttagtc
   102481 ttgtatgtct ttgctccttg gctagcagac ttgtctggcg tgggcaaaga cttgatccca
   102541 atcatgcaaa gcttggcttg gggagtcttg attttcccgt ctatgagtgt tatccgagga
   102601 tttttccaag ggatgaataa cctcaaacct tatgccatga gccaaattgc tgagcaggtc
   102661 attcgtgtta tctggatgct cctagcaacc tttatcatta tgaagctcgg ttcaggagat
   102721 tatctagcag ccgttaccca atcaaccttt gctgcctttg tcggtatggt agccagtttt
   102781 gcagtcttga tttatttcct tgcccaagaa ggttcactca aaagagtctt tgaaacagga
   102841 gataagatta acagtaagcg tctcttggtt gataccatta aggaagccat tccttttatc
   102901 ctgacagggt ctgccatcca gctcttccag attttggatc agctgacctt tatcaatagt
   102961 atgagctggt ttaccaacta cagcaatgag gacttggttg tcatgttttc ttatttctca
   103021 gccaatccta ataaaatcac gatgattttg atttctgtag gggtttcgat tgggagtgtt
   103081 ggtttgccac ttttgacgga aaactatgtc aagggggact tgaaagcagc ttctcgtctg
   103141 gttcaggaca gtctcaccct actctttatg ttcttgctac cagcaacggt tggagtggtt
   103201 atggtaggag aacctctata tacagtcttc tatggtaagc cagatagttt ggctctgggc
   103261 ttatttgtct ttgcagtttt gcagtctatt attttaggct tgtacatggt cttgtctcca
   103321 atgcttcagg ccatgttccg caaccgcaag gccgttctct attttatcta tggttctatt
   103381 gccaagctag tcttgcaact acctaccatc gccctcttcc acagttatgg tcctttgatt
   103441 tcaacaacca ttgctctcat cattcctaac gtcttgatgt atcgggatat ttgtaaagta
   103501 actggtgtca agcgcaaggt gattttgaag cgaaccattt taatcagttt gctgacccta
   103561 gtcatgtttc tgttaatagg aaccatccag tggctgttag gatttttctt ccaaccaagt
   103621 ggacgtttgt ggagcttctt ttatgtagct cttgtcggtg ccatgggggg tggactttat
   103681 atggttatga gtctgcgtac ctatttatta gataaggtaa taggaaaagc ccaagcagat
   103741 cgcctgcgag caaaatttaa gctttcgtaa ggtagcattt ataaataaaa ggaataagtt
   103801 gaacaatctt ttaggagaac ttgaaactta ttcctttttt agcgtcaaaa tagctaaaat
   103861 tatctttcaa aaatagaaaa tgaggttttt ttgatttttt ggaaaaaaca attgactaaa
   103921 caaaccaaga gttgtataat aaaacaaata tttaaagcag gaggttctgg aaatgaaaaa
   103981 gtctaagagc aaatatctaa ccttggcagg tcttgtcctg ggtacaggag ttttattgag
   104041 cgcgtgtgga aattctagca ctgcatcaaa aacctataac tatgtttatt caagtgatcc
   104101 atctagtttg aactatctag cagaaaaccg cgcagcaaca tccgatattg ttgcaaattt
   104161 ggtagacggg ttattagaaa atgaccaata tgggaatatt attccatcat tagcagagga
   104221 ttggactgtt tctcaggacg gtttgaccta tacctacaaa cttcgtaagg atgccaagtg
   104281 gtttacttct gagggagaag aatatgcgcc tgtaactgcc caggattttg tgacaggttt
   104341 gcaatatgca gctgataaaa aatcagaagc tttgtatcta gtgcaggact ctgttgctgg
   104401 tttggatgac tatatcactg gtaaaacaag cgacttttca actgtcggtg tcaaggcact
   104461 tgatgaccaa acggttcaat atactttggt taaaccagaa ctttactgga attcaaaaac
   104521 acttgcaacg atactttttc ctgttaatgc agatttcctg aaatcaaaag gggatgattt
   104581 tgggaaggcg gatccatcta gtattttgta caatggacct ttcttgatga aagcacttgt
   104641 ctcaaaatct gctattgaat ataagaaaaa ccctaattac tgggatgcta agaatgtctt
   104701 tgtagacgat gtgaaattga cctactatga tggtagcgac caagaatcac tggaacgtaa
   104761 ttttacagct ggtgcttata ctacggctcg tctttttcct aacagctcca gctatgaagg
   104821 gattaaagaa aaatacaaaa acaatatcat ctatagtatg caaaattcaa cttcatattt
   104881 ctttaatttt aacctagata ggaagtctta caattatact tctaaaacaa gtgacattga
   104941 aaagaaatcg actcaggaag cagttctcaa taaaaacttc cgtcaggcta tcaattttgc
   105001 ttttgacaga acatcttatg gggctcagtc cgaagggaaa gaaggtgcaa caaagatttt
   105061 gcgtaaccta gtggttcctc caaactttgt cagtatcaag ggaaaagact ttggtgaagt
   105121 tgtagcctct aagatggtca actatggtaa ggaatggcaa ggtatcaact ttgcggatgg
   105181 tcaagaccct tactacaatc ctgagaaagc caaggctaag tttgcggaag ctaagaaaga
   105241 actcgaagca aagggtgttc aattcccaat ccacttggat aagactgtgg aagtaacaga
   105301 taaagtaggc atacaaggag ttagttctat caaacaatca attgaatctg ttttaggttc
   105361 tgataatgta gtgattgaca ttcagcaatt aacatcagat gagtttgaca gttcaggcta
   105421 ctttgctcaa acagctgctc agaaagacta tgatttatat catggcggtt ggggacctga
   105481 ttatcaagac ccgtcaacct atcttgatat ctttagtgtc aagaatggtg gggttctaca
   105541 aaatcttgga ctcgaccctg gtgaagccaa tgacaaggct aaggcagttg gacttgacac
   105601 ttatactcaa atgttggaag aggctaataa ggagcaagac ccagccaaac gttatgagaa
   105661 atatgctgat attcaagctt ggttgattga tagttcttta gttcttccaa gtgtttcgcg
   105721 tgggggaaca ccatcattga gaagaaccgt accatttgct gctgcctatg gtttaaccgg
   105781 tacaaaaggg gttgaatcat ataaatacct caaagtacaa gataagattg tcacaacaga
   105841 cgaatatgca aaagccagag aaaaatggtt gaaagaaaaa gaagaatcca ataaaaaagc
   105901 ccaagaagaa ttggcaaaac atgtcaaata aaatctaatt gtagataagt ttgtgtaaga
   105961 agtctttgtg cttaaaaacg cataatatca ggtatataaa atcctagatg ttatgcgttt
   106021 tgttatagga agatttatta gattttatcc tcaaattgag ttattcccga ctttatccgt
   106081 tgaaatatta taaggagtat ttatgaaatt aaaattatta agagtagata ctaaggtgat
   106141 tatggggagt ttcttacttg ttctgtctag tctacttgct ttgttgcttc cccttatctt
   106201 aaagggttta atagatggga gttctattga aaatataggt tccaaagtat ttcaatcgtt
   106261 tttgattttt attggtcaag ccttgttttc ttctattggt tactatctgt ttagtcaatc
   106321 gggtgaaaaa aagatagcaa aaatcaggaa aaaagtgata gaggggttga tttatgcaga
   106381 gaaatccttc tttgataaga gccaaagtgg ggagttgact tctgccattg tcaatgacac
   106441 gagtgtcatt cgtgagtttt taattacgac tttcccaaat attattctga gtttagttat
   106501 ggtacttggt tccattgtag tcttatttag tcttgattgg aatctttctc tacttttatt
   106561 catcactctt ccttgtatga tgtttattat cttgcccctt tccaatatca gtgaaaagta
   106621 tagtcgtcgt ttacaggagg aaatcggatt tttaacaggg caattgactg aaaagattca
   106681 agaacatgaa ttaattaaga ctaaccaagc agagaaaagt gtacaggatg ttttggataa
   106741 ttgtattgaa agggtacaaa acaattcact gaaatcagat agggttactt cttttgagac
   106801 cccgtttgct ctcttattta tctttgcgac tatagctgtg atgctaacct atgggggtta
   106861 tcgggtcagc gcaggatata tatctgtggg aaccttggtt tcgtttttga tttacctctt
   106921 tcaattactt aatcctatta gtaatatagc taattttgta actgtttatt ctaggagcaa
   106981 gggatcttca gttgcactgg agaacttgct tgcagttcct aaagaaaaat ttgagtgagg
   107041 aaaatcggta tcaggacaag ggttgaattt taaccatgtc tattttggtt atgatgaaaa
   107101 tcgacctgtc ttaaaggata ttacttgttc aattttcaag gggcaaaaaa ttgcttttgt
   107161 tggaccatct ggatcaggaa aatcaacgat tgtgcgtttg ttagagcagt tttataaacc
   107221 gctttcagga gatattctaa tggagcaatc aagtatatat gattttaact taaaagaatg
   107281 gagaagtaaa atcgcttggg tttcacaaaa taatgcagtc ttatctggca gtattcgtga
   107341 caatctttgt ctcggtttga atcgcttagt aactgatgat gaattgatga aagtgctaga
   107401 cttagtatca ctaggtgatg agattcgctc catgaaagag ggactagata ctgaagttgg
   107461 tgaacgcgga cgattcttgt caggggggca aagccaaaga cttcaaatag ctagaaccta
   107521 cttaaaagat gctgaaattc ttatatttga tgaagctact gctaatcttg atgcggattc
   107581 tgagtatgcg attatcagta gcctctattc tgtattaaag gagaagacgg ttgtgattat
   107641 agcgcatagt ttgtcaacgg taaaagatgt ggattgtatt ttcttcttag aggaggggaa
   107701 aatcactggc tcaggaactc ataaggaact actggaaaat catgagcgtt atgctcgttt
   107761 tgtgcaggag caaatgatag agtgaagtgt cttttgagat tcaccatttt atagtctatt
   107821 aaagggagca ggaaaaactc cctttttata tagtttgaaa ctataactag ctcttgaaaa
   107881 gaagaaaatg agttgatgaa aataagtggt acaatagtta ctatagattt ggaggtattg
   107941 tatgagcaag gaattacaca ttaacacaat tttggcccag gcgggtatta agtcagatga
   108001 agcgacaggt gcattggtga caccgcttca tttttcaacg acctatcagc atccagagtt
   108061 tggtcgatct actgggtttg actatacgcg cactaaaaat ccaactcgta gtaaggctga
   108121 ggaagtcttg gcgactattg agtcagcaga ctatgcctta gcgactagct cagggatgtc
   108181 agctattgta ctggccttta gcggctttcc agtaggaagt aaggtcttgg cagtgcgtga
   108241 tctttacggc ggttcttttc gctggtttaa ccaagtggag caggaaggtc gtttccattt
   108301 tacctatgcc aatacagaag aagagttgat tgccgagtta gaaaaggatg tggatgttct
   108361 ctatatcgaa accccaacca atcccttgat gttggaattt gatatcgaaa aactagcaaa
   108421 attggctcat gctaagggtg ccaaagtggt ggtggacaat accttctata gccctatcta
   108481 ccaacgtccg attgaagatg gagcagatat cgttctccat tcagcaacca agtatctagc
   108541 aggccacaat gatgtcttgg ctggagtggt tgtgaccaat agtttagaac tatacgagaa
   108601 gcttttttac aatctcaata caacaggggc agtcttgtct ccatttgaca gctaccagtt
   108661 gcttcgtggt ctcaagacct tgtctcttcg tatggagcgc tcaacagcta acgcccaaga
   108721 agtggttgcc tttttgaagg attctccagc agttaaggaa gttctctaca ctggtcgtgg
   108781 aggcatgatt tcctttaaag tagccgatga aacacgcatt cctcatattt tgaacagtct
   108841 caaggtcttc tcttttgcgg aaagtttggg cggagtggaa agtcttatta cttatccaac
   108901 gactcaaact catgctgata ttccagcaga agtacgccat tcttatggtt tgacagatga
   108961 cctcttgcgt ttgtctattg ggattgagga tgctagagat ttgattgcag atttgcgcca
   109021 agccttagaa ggataagaca aagatgggaa aatatgattt tacaagcctg cccaaccgtt
   109081 tagggcacca tacctataaa tggaaagaaa cagaaacgga tagtgaagtt ctaccagctt
   109141 ggatagcgga tatggacttt gtggtcttgc ctgaaatccg ccaagtcgtg caaacttacg
   109201 cagaccaact ggtttatggt tatacctatg ccagtgaaga cttaattaag gaagttcaaa
   109261 agtgggaagc tacacaatac ggttacaact ttgacaaaga ggctcttgtc tttatcgagg
   109321 gtgtggtacc agccatctca acagctattc aaacctttac aaaagaaggc gatgcggttt
   109381 taattaacac gcctgtctac ccaccctttg ctcgcagtgt caagttgaat aatcgtagat
   109441 tgattactaa ttccttagtg gaaaaggatg gtctgtttga gattgacttt gaccaacttg
   109501 aaaaggattt ggtggaagag gaggttaaac tctatattct ttgcaaccct cacaatcctg
   109561 gtggacgtgt ttgggaaaaa gaagtgttgg agaagattgg ccaactctgc caaaaacacg
   109621 gtgttttgtt agtttcggat gagattcacc aagatttgac cctctttggt cacaaacacc
   109681 agtctttcaa taccatcaat cctgccttca aaaattttgc tatcgtcttg agcagtgcca
   109741 ctaaaacatt taatattgct ggaacaaaaa attcctatgc agtcattgaa aatcctaagt
   109801 tgagactagc tttccagaaa cgcctgttgg ccaataatca gcatgaaatt tcaggcttgg
   109861 gttatttggc gacagaagct gcctatcgat acggtaaaga ttggctagag gaactcaagc
   109921 aagtctttga agaccacatc aattatgtgg tggatctatt tggaaaagag actaaaatca
   109981 aggtcatgaa accgcaaggt acctacttga tttggcttga cttttcagcc tatgacctga
   110041 ctgatgaaac attgcaagag ttgttgagaa atgaagccaa ggttatcctc aaccgtggtt
   110101 tggattttgg agaggaagga agtctccatg cccgcatcaa tatagctatg cccaaatctc
   110161 tgttgcaaga agtctgtcag cggattgtgg ctacttttgc caaacgttaa aaatccagcc
   110221 ttctaggaga aaagtcttcc tagaaggcta ttttcatagg cgaaaatatg gtataataaa
   110281 aagataaggt aaaggtgaaa atatggctaa attgattccg gggaaaattc gtatcgaagg
   110341 tgttgccctt tatgaaactg gtaaggttga tatcatcaag gaaaagaaca atcggctcta
   110401 cgctcgcgtt gcagaagaag aactgcgcta tagtttagag gatgatttgg ttttttgtgc
   110461 ctgtgatttt tttcaaaaga ggggttactg tgtgcatttg gcagcgctag agcattttct
   110521 gaaaaatgat gagcgtggtc aggaaatctt gtggagtctg gaagaaggtc atgaagaaaa
   110581 agaggctgtt gaaaccaagg tgaccttggg tggcaagttt ttggatcgaa ttttatctcc
   110641 aaaatcagaa tgcgcctatg agttatcagc tgtgggtcag gtggaagcag gaaccaatca
   110701 tatcttgtgg actctgagaa tcggccaaat caatagccaa aaatactatg tcattcggga
   110761 tattccactt tttttaagga ttgtcgagca gagaaagtcg tatatgattg gcaagattta
   110821 tgaggagtct ctttcttggg aagcctttga tgatgccagc caagaacttt tgactttctt
   110881 gcacggacta acggaggaag ggctggtttc agacctcttt ttccaaaacc aaggtcggca
   110941 cctctttttc cctctgacct tttttgagca gggtgtgaat ttactgatgg ccttgcccca
   111001 ttttcaattt gaccatcaag tggatagcta ccaaaccctg ctttttcagg atatgcatgc
   111061 tgatgccaat ctatttgcct ttacagtaac agaatactcg gactattttg aaatggaaat
   111121 cagtgagagt cctagggtca atgtctttta tcagggagca gtacttttcc ataaaggtca
   111181 ggtttatttt ttaacagacc agcagatgcg tcttctcaag gaaattaaag cgttacctgt
   111241 gggtcaacaa ggaaagaaat acctgcaatt tgatagcagt gatcgagaca aattggcctc
   111301 ctgtctgact ctttttatcc agatgggcac cgtttcagct ccagaacgtc tacaaatcaa
   111361 aacttttgcg ccctcttttt actttgacag ggaagaagat aatcggattc gtttagaaat
   111421 tcagtttgat tatggaaata gacaggtatc tagccgacaa gagctagaag aattaccatt
   111481 ttcaagtgac gcggacttag aagaaagaat tttccaagtc tgtttggctg cgggctttga
   111541 ggccgatttt caatcttggc gtcaggcctt aaaagcggag tctgtctatc atttttttca
   111601 tgatatcatt ccagtctttg aaaaactcgg gcatgttgac ctatcagata aactagaaga
   111661 gctttatagc ctagcgagtc ctcaggtgca gattgcctcc aagggaggtc tcttggaaat
   111721 ccagtttgat tttcaaaata ttgtccagga ggaaatcgac caagccatgc aggccttggt
   111781 tgccaatcag gatttttata ttgattcgtc taatcaagtt tactttttcg atgaagaaac
   111841 caagaaaatt cgccaaaatt tacaggaact ggggcaattt gaattaaaag atgggacctt
   111901 gcaggctcgg aaatccttga cctacagttt agctcatctc tttgaagggc gagaccgtgt
   111961 ttctttttca caagaattcc agaatctggc ccaggatttg acgcatccag aggactttcc
   112021 tttgcaagca actcaggtca aggctgactt gcgagattat caggaaaagg gaattggctg
   112081 gttgcagatg ctccatcatt atggttttgg tgggattttg gctgatgata tgggacttgg
   112141 gaaaaccctt cagaccattg cttttttgac tagtcaagtg acaaaagaaa gtcgggtttt
   112201 gattctcgct ccgtcgggtt tgatttacaa ctgggcagat gagtttcaga aatttgctcc
   112261 acagttggat gtgactgttg ttcatggttt gaaagcaagt cgtgaggaga ttcttgccga
   112321 gagccatcaa atctatgtga ctagctatgc caccttccgt caggacagtg agctttatca
   112381 ggggatggcc tttgacttcc ttttcttaga tgaagctcag gtcatgaaaa atgcccagac
   112441 caagattgcc cagaccttga gacaatttgt ggtgccgtcg gtctttgcct tgtcaggaac
   112501 tccgattgaa aaccatctgg gtgagttgtg gtctattttc caaatcgtca tgcccggact
   112561 tttgccaagc aagaaagaat ttatgaaatt gccagcagag cgagtggctc agtttatcaa
   112621 gcctttcgtg atgcgacgca agaaagaaga agttctgact gaattgccag acttgattga
   112681 ggtggtttat aaaaatgaac tggaagacca gcaaaaggct atttaccttg cccagttaca
   112741 acagatgcga gaccatctgg ctcaagtgtc agaacaggaa tttcagcgaa gtcgtgtgga
   112801 aattttatct ggtttgatgc gcttgcgtca aatatgtgac actcctgccc tgtttatgga
   112861 agattatcag ggagccagcg gcaaactaga tagtctccga gacctactgg tacaggtggc
   112921 agacggcgga caccgtgtct tgattttctc tcagttcaag ggaatgttgg aaaaaattga
   112981 acaagaactg ccagacttgg gcctgacttc ctttaaaatt acgggttcaa ccccagccaa
   113041 ggaaagacaa gacatgacca aggcctttaa ccaaggagaa agagatgcct ttctgatttc
   113101 cctcaaggct ggtggggtcg gtctgaacct gacaggtgca gatacagtga tcttggttga
   113161 cctttggtgg aatcctgcgg tggaagcgca agccattggc cgtgcccatc ggatgggtca
   113221 ggaagaaacg gttgaggtct atcgcttggt gaccaaggga accattgaag aaaaaattca
   113281 ggaactccaa gaacaaaaga aacatctggt gtcacaagta ttggacggca cagagtcacg
   113341 tggtagtctg accctagcag aaattagaga aattttggga atttctgaag ccagcacttg
   113401 aaaaatcaag acaatacgct ataatgaagt gttgaaagga aatagaaaat gaaacaagaa
   113461 cgatttccat tggtgtcaga tgacgaggtc atgttgactg aaatgccagt catgaatctc
   113521 tatgatgagt ctgatctgat cagtaatatc aagggtgagt atcgagataa aaattattta
   113581 gaatgggctc ctattgctga agaaaaacca gtaaaaccga ttgaaaagca agtcgaaaaa
   113641 cctaaaaagg ctcctttagg ggttaaaaaa gaaggaaaga gctatgcgga ggtggcgcgt
   113701 gaagaagcgc gtgcggactt gaaaaagaaa cgctctgcta actacctaac tcaggatttc
   113761 agccttgcga gacgtcattc tcagcccagt ctagttagac agggcaatca accgacaact
   113821 cctttccaaa aggaaaatcc tggtgaattt gtcaaatata gccaaaaatt gacccagtct
   113881 cattatatct tggcggaaga agttcattct atccctacca agaatgaaga agtgtcagca
   113941 cctgctccaa agaaaaacaa ttatgatttt ctaaagaaga gccaaatcta caataaaaaa
   114001 agtaaacaaa cagaacaaga acgtcgggtt gcccaagagt tgaatctgac cagaatgaca
   114061 gaatagggga gaaaacatgt caaagacata tcattttatc ggaattaagg gatcagggat
   114121 gagtgccttg gccttgatgt tgcaccagat ggggcacaag gttcagggat cagatgttga
   114181 aaagtactac tttacccaac gcggtcttga gcaggcagga attaccattc ttccttttga
   114241 tgaaaagaat ctagacggtg atatggaaat tatcgctgga aatgcctttc gtccagataa
   114301 caacgtcgaa attgcctatg cggaccaaaa tggtatcagc tacaaacgtt accatgagtt
   114361 tctaggtagc tttatgcgtg actttgttag catgggagta gcaggagcac atggaaaaac
   114421 ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt acagatacca gcttcttgat
   114481 tggagatggg acaggtcgtg gttcggctaa tgccaaatat tttgtctttg aatctgacga
   114541 atatgagcgt cacttcatgc cttaccaccc agaatactct attatcacca acattgactt
   114601 tgaccatcca gattatttca caagtctcga ggatgttttc aatgccttta acgactatgc
   114661 caaacaaatt accaagggtc tttttgtcta tggtgaagat gctgaattgc gtaagattac
   114721 gtctgatgca ccaatttatt attatggttt tgaagctgaa ggcaatgact ttgtagctag
   114781 tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt catttccgtg gacaaaactt
   114841 ggggcaattc cacattccaa cctttggtcg tcacaatatc atgaatgcga cagccgttat
   114901 tggtcttctt tacacagcag gatttgattt gaacttggtg cgtgagcact tgaaaacatt
   114961 tgccggtgtt aaacgtcgtt tcactgagaa aattgtcaat gatacagtga ttattgatga
   115021 ctttgcccat catccaacag aaattattgc gaccttggat gcggctcgtc agaaataccc
   115081 aagcaaggaa attgtagcag tctttcaacc gcataccttt acaagaacca ttgccctgtt
   115141 ggacgacttt gcccatgctt taaaccaagc agatgctgtt tatctagcgc aaatttatgg
   115201 ctcggctcgt gaagtagatc atggtgacgt taaggtagaa gacctagcca ataaaatcaa
   115261 caaaaaacac caagtgatta ctgttgaaaa tgtttctcca ctcctagacc atgacaatgc
   115321 tgtttacgtc tttatgggag caggagacat ccaaacctat gaatactcat ttgagcgtct
   115381 cttgtctaac ttgacaagca atgttcaata ggatgttccc atggaaattc caattaagat
   115441 cattcaggca agcaagtttg atttgcctga gataggggca cttcagacct cgtcttttcc
   115501 agctgaaaag cagcaacttt cccatatttt agaagaaagt atccgtaagt gtgcggatac
   115561 ctttcttcta gctagggatg aaaatcaact tttaggctat attttatcaa gtccccagtc
   115621 agacaatccg caatgtctaa aagtacattc tttagtcatc gagtctgacc atcagagaca
   115681 gggcctggga acacttcttc ttgcagcctt gaaagaggtg gcagttgagc tggattacaa
   115741 agggattcgt ttggagagtc ctgatgagct gctttcctat tttgaaatga acggttttgt
   115801 tgatgaagaa gaaattttgc tctatgcaac tagccagggc tatagtatga tttggtttaa
   115861 tcccttttat ctggaggaac aatgaaaatc agacaagcaa gattagaaga tttggatcgg
   115921 attgttgaac ttgaatttga aaatttttcg gtcgaagaag ccattcctcc ttctgtcttt
   115981 gaagcacatt tgagagaaat tcagacctct tttctggttg ctgaaaaaga aggaagaatc
   116041 atgggttata tcgaaggacc agttggcctg caccgccatc tgcaagacca gtcttttaca
   116101 gaagaaataa aagactatag tcatgagcct ggtggttata tctctgtgac ctgtctgtct
   116161 attgccaagg aggcacaggg actcggactg ggtcagaaat tgctgacagc cttgaaagaa
   116221 gttgctcttg aagatgagag agatggcatt aatctaacct gtcatgacta tctcatcgcc
   116281 tattatgaaa aacatggatt tgtcaacgaa ggccagtccc agtcaacctt tgcaggggaa
   116341 acatggtatg atatggtctg ggaaatgaaa aaataagtta ggaaaagtat catagattgc
   116401 tttttttgga cttttaagat ataatattat ggattatcaa caaggaggaa aaacttttga
   116461 gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga gcagattctg agagatttag
   116521 aaaaagtaaa aggctatgat gaagttctga aagaagatga ggcagtagtt cgcactcctg
   116581 caaatgaacc ttcagctgaa gaactcatgg ctgattcctt gtcaacggta gaggagatta
   116641 tgagaaaagc tcctaccgtg cctactcacc caagtcaagg tgtaccagct tctccagcag
   116701 atgagattca aagagaaact cctggtgttc caagtcatcc aagtcaagat gtaccttctt
   116761 ctccagcgga agaaagtgga tcaagaccag gtccaggtcc tgttagacct aagaaacttg
   116821 aaagagaata caatgaaacc ccaacaaggg tagctgtttc ctatacgacg gcagagaaaa
   116881 aagcagaaca agcaggtcca gaaacaccta cgcctgctac agaaacagtg gatatcatca
   116941 gagatacatc acgtcgtagc cgtagagaag gagcaaaacc cgttaagcct aagaaagaga
   117001 agaagtcaca tgtgaaagct tttgtgattt cattccttgt attccttgcc ttgctctcag
   117061 caggtggtta ctttggttac cagtacgtgc tagattcctt attacctatc gatgctaatt
   117121 ctaagaaata tgtgacggtt ggaattccag aaggttcaaa cgttcaagaa atcggtacga
   117181 cgcttgaaaa agctggtttg gtaaagcatg gtctgatttt tagtttttat gccaagtata
   117241 aaaattatac cgacttgaaa gcaggttact acaatttgca aaagagtatg agtacagaag
   117301 acttactcaa agagttgcaa aaaggtggaa cagatgaacc gcaagaacct gtacttgcga
   117361 ctttgacaat tccagaaggt tataccttgg atcagattgc tcaaactgtg ggtcaattgc
   117421 aaggtgactt caaagagtct ttgacagcgg aggctttctt ggctaaagtt caagatgaga
   117481 cgtttatcag tcaagcagta gcgaaatatc ctactttact ggaaagtttg cctgtaaaag
   117541 acagcggtgc gcgttatcgt ttggaaggat accttttccc agctacatac tctatcaagg
   117601 aaagcacaac tattgagagc ttgattgatg agatgttagc tgctatggat aagaacctat
   117661 ctccttacta tagtactatc aaatctaaaa acttgactgt caatgagttg ttgaccattg
   117721 cttccttggt cgaaaaagaa ggtgccaaga cagaagatcg taagctcatt gcaggtgtat
   117781 tctacaatcg tttgaatcgt gatatgccac ttcaaagtaa tattgcaatc ttgtatgccc
   117841 aaggaaaact ggggcaaaat atcagtctag ctgaggatgt tgcgattgat accaacattg
   117901 attcacctta taatgtttat aaaaatgtag gtctcatgcc tggtccagtc gatagtccaa
   117961 gtctggatgc gattgagtca agcatcaatc aaactaagag cgataacctc tactttgtag
   118021 cagatgtcac agaaggcaag gtctactatg ctaacaatca agaagaccac gaccgcaatg
   118081 tcgctgaaca tgtcaacagc aaattaaact aaacaaacta aaattatgtg atacttcaca
   118141 taattttctt tagaaaatat tatcagaaga aagttgagaa aaatggcaga aaaaacatat
   118201 cctatgaccc ttgaggaaaa ggagaaactt gaaaaagaat tagaagaatt gaaattggtt
   118261 cgtcgaccag aagtggtaga acgcattaag attgcccgtt catacggtga tctttcagaa
   118321 aacagtgagt acgaagcagc taaggatgaa caagcctttg tcgaaggaca aatctctagc
   118381 ttagaaacaa aaatccgcta tgctgaaatc gtcaatagcg acgcagttgc ccaggacgaa
   118441 gtagcgattg gtaaaacagt caccatccaa gaaattggtg aggacgaaga agaagtttat
   118501 attatcgtag gttcagctgg tgcggatgcc tttgcaggta aggtttcaaa tgaaagccca
   118561 attgggcagg ccttgattgg caagaaaaca ggtgacacag caaccattga aacgcctgtt
   118621 ggtagctatg atgtaaaaat cttgaaggtt gaaaaaacag cctaaaaaca gaaaaaggag
   118681 tggggaggcg atgtgcttca ctcactcctt tttccatttt gctattcttc gaaaatctct
   118741 tcaaaccacg tcagcgtcgc cttgccgtat gtatggttac tgactttgtc agtttcat
//
LOCUS       DAVIME010000002        77120 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVIME010000002 DAVIME010000000
VERSION     DAVIME010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.002"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            120..911
                     /locus_tag="VV588_000120"
     CDS             120..911
                     /locus_tag="VV588_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082548.1"
                     /translation="MNFALNKGEIVGQVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKEMLKDIYLNRSK"
     gene            927..1655
                     /locus_tag="VV588_000121"
     CDS             927..1655
                     /locus_tag="VV588_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082549.1"
                     /translation="MKLNKFNFIKENIRDLYSSGVIYLGLIISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRIISRDFSHNTISLFYNQQKNRMIYLLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            2041..2250
                     /locus_tag="VV588_000122"
     CDS             2041..2250
                     /locus_tag="VV588_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7082550.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2240..2728
                     /locus_tag="VV588_000123"
     CDS             2240..2728
                     /locus_tag="VV588_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082551.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            2844..4304
                     /locus_tag="VV588_000124"
     CDS             2844..4304
                     /locus_tag="VV588_000124"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU7082552.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISYMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4301..5125
                     /gene="nadE"
                     /locus_tag="VV588_000125"
     CDS             4301..5125
                     /gene="nadE"
                     /locus_tag="VV588_000125"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU7082553.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5422..5973
                     /locus_tag="VV588_000126"
     CDS             5422..5973
                     /locus_tag="VV588_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7082554.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            6687..7380
                     /locus_tag="VV588_000127"
                     /pseudo
     CDS             6687..7380
                     /locus_tag="VV588_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            7434..7823
                     /locus_tag="VV588_000128"
     CDS             7434..7823
                     /locus_tag="VV588_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU7082555.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(8484..9512)
                     /gene="queA"
                     /locus_tag="VV588_000129"
     CDS             complement(8484..9512)
                     /gene="queA"
                     /locus_tag="VV588_000129"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU7082556.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            9663..10370
                     /locus_tag="VV588_000130"
     CDS             9663..10370
                     /locus_tag="VV588_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU7082557.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            10448..10957
                     /locus_tag="VV588_000131"
     CDS             10448..10957
                     /locus_tag="VV588_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082558.1"
                     /translation="MNKEEFLKIKEAYKSARTEERKSIIGFITKKKDKEGNFLFTKSK
                     DKPYTTRNQYSGGGGNKKYTSGSRLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPN
                     SKELHVLYDRIGILFEQSKKIPIFKDCYTITKVSDAFLKMETTNWELPLSKADMEEMV
                     NYIINHYEE"
     gene            11037..11213
                     /locus_tag="VV588_000132"
     CDS             11037..11213
                     /locus_tag="VV588_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU7082559.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            11343..12278
                     /locus_tag="VV588_000133"
     CDS             11343..12278
                     /locus_tag="VV588_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU7082560.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            12271..13059
                     /locus_tag="VV588_000134"
     CDS             12271..13059
                     /locus_tag="VV588_000134"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU7082561.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            13060..13443
                     /locus_tag="VV588_000135"
     CDS             13060..13443
                     /locus_tag="VV588_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU7082562.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            13459..13848
                     /locus_tag="VV588_000136"
     CDS             13459..13848
                     /locus_tag="VV588_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU7082563.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            13932..15062
                     /locus_tag="VV588_000137"
     CDS             13932..15062
                     /locus_tag="VV588_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU7082564.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            15067..15804
                     /locus_tag="VV588_000138"
     CDS             15067..15804
                     /locus_tag="VV588_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU7082565.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            15815..16588
                     /locus_tag="VV588_000139"
     CDS             15815..16588
                     /locus_tag="VV588_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU7082566.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            16578..17195
                     /locus_tag="VV588_000140"
     CDS             16578..17195
                     /locus_tag="VV588_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU7082567.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            17405..17806
                     /locus_tag="VV588_000141"
     CDS             17405..17806
                     /locus_tag="VV588_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU7082568.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            17806..18084
                     /locus_tag="VV588_000142"
     CDS             17806..18084
                     /locus_tag="VV588_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU7082569.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            18074..18847
                     /locus_tag="VV588_000143"
     CDS             18074..18847
                     /locus_tag="VV588_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU7082570.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            18848..20152
                     /locus_tag="VV588_000144"
     CDS             18848..20152
                     /locus_tag="VV588_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU7082571.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            20726..21604
                     /gene="pstS"
                     /locus_tag="VV588_000145"
     CDS             20726..21604
                     /gene="pstS"
                     /locus_tag="VV588_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU7082572.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            21604..22521
                     /gene="pstC"
                     /locus_tag="VV588_000146"
     CDS             21604..22521
                     /gene="pstC"
                     /locus_tag="VV588_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU7082573.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            22511..23395
                     /gene="pstA"
                     /locus_tag="VV588_000147"
     CDS             22511..23395
                     /gene="pstA"
                     /locus_tag="VV588_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU7082574.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            23406..24209
                     /gene="pstB"
                     /locus_tag="VV588_000148"
     CDS             23406..24209
                     /gene="pstB"
                     /locus_tag="VV588_000148"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU7082575.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            24222..24980
                     /gene="pstB"
                     /locus_tag="VV588_000149"
     CDS             24222..24980
                     /gene="pstB"
                     /locus_tag="VV588_000149"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU7082576.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            24992..25645
                     /gene="phoU"
                     /locus_tag="VV588_000150"
     CDS             24992..25645
                     /gene="phoU"
                     /locus_tag="VV588_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU7082577.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            25802..26617
                     /locus_tag="VV588_000151"
     CDS             25802..26617
                     /locus_tag="VV588_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU7082578.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
     gene            complement(26637..27908)
                     /locus_tag="VV588_000152"
     CDS             complement(26637..27908)
                     /locus_tag="VV588_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU7082579.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            28050..28781
                     /gene="budA"
                     /locus_tag="VV588_000153"
     CDS             28050..28781
                     /gene="budA"
                     /locus_tag="VV588_000153"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU7082580.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            28791..29543
                     /locus_tag="VV588_000154"
     CDS             28791..29543
                     /locus_tag="VV588_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEU7082581.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            29655..30605
                     /gene="murB"
                     /locus_tag="VV588_000155"
     CDS             29655..30605
                     /gene="murB"
                     /locus_tag="VV588_000155"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU7082582.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            30664..31821
                     /locus_tag="VV588_000156"
     CDS             30664..31821
                     /locus_tag="VV588_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082583.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            31802..32608
                     /locus_tag="VV588_000157"
     CDS             31802..32608
                     /locus_tag="VV588_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082584.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            32605..33378
                     /locus_tag="VV588_000158"
     CDS             32605..33378
                     /locus_tag="VV588_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082585.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            33375..34445
                     /locus_tag="VV588_000159"
     CDS             33375..34445
                     /locus_tag="VV588_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU7082586.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            34706..34945
                     /locus_tag="VV588_000160"
     CDS             34706..34945
                     /locus_tag="VV588_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082587.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            35220..35705
                     /locus_tag="VV588_000161"
     CDS             35220..35705
                     /locus_tag="VV588_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU7082588.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            35727..38345
                     /gene="alaS"
                     /locus_tag="VV588_000162"
     CDS             35727..38345
                     /gene="alaS"
                     /locus_tag="VV588_000162"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU7082589.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(38435..39889)
                     /locus_tag="VV588_000163"
     CDS             complement(38435..39889)
                     /locus_tag="VV588_000163"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU7082590.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            40068..40817
                     /locus_tag="VV588_000164"
     CDS             40068..40817
                     /locus_tag="VV588_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082591.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            40798..42432
                     /locus_tag="VV588_000165"
     CDS             40798..42432
                     /locus_tag="VV588_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082592.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            43117..44280
                     /locus_tag="VV588_000166"
     CDS             43117..44280
                     /locus_tag="VV588_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU7082593.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            44277..44954
                     /locus_tag="VV588_000167"
     CDS             44277..44954
                     /locus_tag="VV588_000167"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU7082594.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            44944..45798
                     /locus_tag="VV588_000168"
     CDS             44944..45798
                     /locus_tag="VV588_000168"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU7082595.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            45817..46884
                     /locus_tag="VV588_000169"
     CDS             45817..46884
                     /locus_tag="VV588_000169"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU7082596.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            46894..48060
                     /gene="aroC"
                     /locus_tag="VV588_000170"
     CDS             46894..48060
                     /gene="aroC"
                     /locus_tag="VV588_000170"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU7082597.1"
                     /translation="MRYLTAGESHGPRLTAIIDGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            48070..49173
                     /locus_tag="VV588_000171"
     CDS             48070..49173
                     /locus_tag="VV588_000171"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU7082598.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            49184..49522
                     /locus_tag="VV588_000172"
     CDS             49184..49522
                     /locus_tag="VV588_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU7082599.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            49614..50897
                     /gene="aroA"
                     /locus_tag="VV588_000173"
     CDS             49614..50897
                     /gene="aroA"
                     /locus_tag="VV588_000173"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU7082600.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLSPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            50890..51366
                     /locus_tag="VV588_000174"
     CDS             50890..51366
                     /locus_tag="VV588_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU7082601.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            51363..52211
                     /gene="pheA"
                     /locus_tag="VV588_000175"
     CDS             51363..52211
                     /gene="pheA"
                     /locus_tag="VV588_000175"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU7082602.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            52208..53482
                     /gene="psr"
                     /locus_tag="VV588_000176"
     CDS             52208..53482
                     /gene="psr"
                     /locus_tag="VV588_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU7082603.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     RNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            53761..54606
                     /locus_tag="VV588_000177"
     CDS             53761..54606
                     /locus_tag="VV588_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU7082604.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            54596..55699
                     /locus_tag="VV588_000178"
     CDS             54596..55699
                     /locus_tag="VV588_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU7082605.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            55701..56687
                     /locus_tag="VV588_000179"
     CDS             55701..56687
                     /locus_tag="VV588_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU7082606.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            56703..58136
                     /locus_tag="VV588_000180"
     CDS             56703..58136
                     /locus_tag="VV588_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU7082607.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            58165..59199
                     /locus_tag="VV588_000181"
     CDS             58165..59199
                     /locus_tag="VV588_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU7082608.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            59341..60078
                     /gene="mecA"
                     /locus_tag="VV588_000182"
     CDS             59341..60078
                     /gene="mecA"
                     /locus_tag="VV588_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU7082609.1"
                     /translation="MKMKQISDTTLKITISLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFAEDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            60229..61515
                     /locus_tag="VV588_000183"
     CDS             60229..61515
                     /locus_tag="VV588_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU7082610.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVVHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            61517..62386
                     /locus_tag="VV588_000184"
     CDS             61517..62386
                     /locus_tag="VV588_000184"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU7082611.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            62636..63574
                     /gene="msrB"
                     /locus_tag="VV588_000185"
     CDS             62636..63574
                     /gene="msrB"
                     /locus_tag="VV588_000185"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU7082612.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            63632..65356
                     /locus_tag="VV588_000186"
     CDS             63632..65356
                     /locus_tag="VV588_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082613.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            65358..67109
                     /locus_tag="VV588_000187"
     CDS             65358..67109
                     /locus_tag="VV588_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082614.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            67456..68715
                     /locus_tag="VV588_000188"
     CDS             67456..68715
                     /locus_tag="VV588_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU7082615.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    68791..68926
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            68965..69465
                     /locus_tag="VV588_000189"
     CDS             68965..69465
                     /locus_tag="VV588_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU7082616.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            69541..69909
                     /gene="rplL"
                     /locus_tag="VV588_000190"
     CDS             69541..69909
                     /gene="rplL"
                     /locus_tag="VV588_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU7082617.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            70096..70266
                     /locus_tag="VV588_000191"
     CDS             70096..70266
                     /locus_tag="VV588_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082618.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            70266..70514
                     /locus_tag="VV588_000192"
                     /pseudo
     CDS             70266..70514
                     /locus_tag="VV588_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            70528..70868
                     /locus_tag="VV588_000193"
                     /pseudo
     CDS             70528..70868
                     /locus_tag="VV588_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            70861..71241
                     /locus_tag="VV588_000194"
     CDS             70861..71241
                     /locus_tag="VV588_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU7082619.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            71254..71397
                     /locus_tag="VV588_000195"
     CDS             71254..71397
                     /locus_tag="VV588_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082620.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            71490..72077
                     /locus_tag="VV588_000196"
     CDS             71490..72077
                     /locus_tag="VV588_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7082621.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            72279..72416
                     /locus_tag="VV588_000197"
     CDS             72279..72416
                     /locus_tag="VV588_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEU7082622.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            72706..74109
                     /locus_tag="VV588_000198"
     CDS             72706..74109
                     /locus_tag="VV588_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEU7082623.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSSSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            74298..74916
                     /locus_tag="VV588_000199"
                     /pseudo
     CDS             74298..74916
                     /locus_tag="VV588_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            74931..75671
                     /locus_tag="VV588_000200"
     CDS             74931..75671
                     /locus_tag="VV588_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082624.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            75674..76993
                     /locus_tag="VV588_000201"
     CDS             75674..76993
                     /locus_tag="VV588_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082625.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLGDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
BASE COUNT        22858 a        13923 c        17111 g        23228 t
ORIGIN      
        1 gcgcaacttt ttaaaattaa tgagaatcaa agagaaaacc aataatatta atggaggaat
       61 aaaaaatgta agttataaat gtaagtaagc attatggtca ttcaatcatt ctcaaagaca
      121 taaattttgc acttaacaag ggtgaaattg ttggtcaagt agggagaaat ggagttggta
      181 agagtacgtt gatgaaaatt cttgttcaga ataatcaacc gacttcaggt aatattataa
      241 gcagtgataa tgttgggtat ttaatcgaag aaccaaaatt atttttatct aaaacaggtt
      301 tagagaattt aaaatatttg tcaaatttat atggtgttga ctacaatcaa gaaagattta
      361 gaagtttgat ccaagagtta gatttgactc agtctattaa taaaaaagta aagacctatt
      421 ctttgggtac aaaacaaaaa ttagctttgc ttctaactct cgttacggaa cctgatatat
      481 tgattttaga tgaaccgact aatggtttag atattgaatc atcacaaata gttttatcgg
      541 ttctaaaaaa tttagcttta catgaaaatg tgggaatttt aatatcgagt cataaattag
      601 aagatattga agaaatttgt gagagggttc ttttcttgga gaacgggctt ttgacatttc
      661 aaaaagtagg aaaagatagt cataatttct tgtttgagat agctttttca tcagctacag
      721 atagagacat tttcattacc aaacaagaat ttggggatat tgttcaggaa gagggactga
      781 gaattactat gtctgggaat attcaaagta gtgagctttt taaatttttt aacgaaaact
      841 ctattaaagt agttgatttt gaaactaaaa aagagatgct taaagatatt tatctaaatc
      901 gttcaaaata aaggaaggtt ataatcatga aattaaataa atttaatttt attaaggaaa
      961 atataaggga tttatattca tcaggcgtaa tatatctcgg tttgattatc tcgtttatac
     1021 cgccgatatt gcttacattc tttattctaa agactcaagg gacatcgctt ggtattaagc
     1081 atatttcaaa cttttatgct atgctcggta tgttaatggc tgttatacat gctaaccgaa
     1141 ttattagcag ggatttttcc cacaatacga tcagtttatt ttataatcaa cagaaaaatc
     1201 ggatgattta cctcttgtct aattttctat atgccatctc agtttccatt atttatgctt
     1261 tgaatggcat tgtgttacta gtcatagtaa gtaaattggg tattccaggt gatttaggat
     1321 tagattttat agtagctatt gtagtcaata caattttgtt agtcctgttt tattttctat
     1381 tatcttacat tttctattta tacaaattga aaagtggctt ggtatttggt attttagtag
     1441 ctttactact ctttatccct aatatattaa atacgatgat gatgaatact agtaatgatt
     1501 tgtttatcaa agcaattgaa cttcttcctt tttattcttt acctgtattt gtgacttcaa
     1561 atacgatgtc tattagtcag tatcttgtgg taatcactac aatcatttta ttgtactttt
     1621 tcactctcaa gaaaagcaag aagtattcat tttagtttca tttagtatta ttttgcatac
     1681 ctaaaataca ataaaaaaat cagtcatctt ggtatgctcc tgctttcact attcaacacg
     1741 tttttgactt atactaggct catttccaaa agcattatat aatagtgata tgaaaccaac
     1801 taaactaaac aagaaatata agcaataaaa actcgtttaa aagattctac taaagctaat
     1861 actaaataaa aataaaagag taaactagga agtttatttc aaacaaccta aaatactgat
     1921 tttcggctga agataatact ggagtgcaaa ttaatggggt tataataaat agctgatagc
     1981 ttgtgttggt tttggatttt ttaagagtag atgagtatta aaactataag gaggacgaag
     2041 gtggctaaaa atttaaaatt aaaattagct cgggtagagc gtgatttaac acaaggtcaa
     2101 ctggcagagg ctgtcggggt gacacgccag actattggtt tgatagaggc gggaaaatac
     2161 aatcccagtc tctcgctctg ccagtctatt tgcagatgtt tagggaaaac cctagaccaa
     2221 ctattttggg aggaagaaga tgaaaaatag attttattat tatcaattac tagacgaaag
     2281 agaagaacaa ctgttcaata aagcgggctc tgaaagtttc tatatctgca ttgctttgtc
     2341 gctcctatct tatatcattt cagtattagc accaagcctt tttaattcta atatgctgct
     2401 aatcgttatc atcataggga cattttactt tttcaatcgt gcccgttatc tgggagtgac
     2461 ctactatagt cgttttcatt ttacgatttt gggttgtttt ttcctaacct tggctattac
     2521 ggctcttttg atgttgcaga attatcaatt caacatagaa atttatcagc acaatccttt
     2581 gaattttaaa tacctgtctg cttgggtcat tacttatgtc atttaccttc cgtgggtctt
     2641 tattggcaat cttggtctta agagctatgg cgaatgggct cagaaaaaat ttgaacaaga
     2701 tatggatgaa ttggagagtg gagaatagct tgttactctt ttctcaatcc agctaaaatg
     2761 tgatataata gtattaattt attggaatac atgaaagttc ttgaaaattt tcatgggttt
     2821 ctagctaagg aagtaggaaa agtatgtatc cagatgatag tttgacattg cacacggact
     2881 tgtaccagat caacatgatg caggtttact ttgaccaagg gattcacaat aagaaggcgg
     2941 tctttgaggt gtatttccgc caacagcctt ttaagaacgg ctatgcggtt tttgcaggtt
     3001 tggaaagaat tgtgaactat cttgaagact tgcgtttttc agatagtgat atagcctatt
     3061 tggagtcgct tggttatcat ggggcgttct tggattacct tcgcaatttc aagttggagt
     3121 tgaccgttcg ttctgcccaa gaaggggatt tggtttttgc taatgaaccg attgtgcagg
     3181 tggaaggacc tctagcccaa tgtcagttgg tcgaaacggc tcttttgaac atcgtcaact
     3241 accagacctt ggtggcgacg aaggcagctc gtattcgttc ggttatcgaa gatgaaccct
     3301 tgatggagtt tgggacacgt cgggctcaag aaatggatgc ggccatctgg ggaacacgcg
     3361 cagctgtgat tggtggcgcc aatggaacca gcaacgtgcg tgcgggtaag ctctttgaca
     3421 ttcctgtttt gggaacccat gcccatgcct tggtacaggt ttatggaaat gactatgaag
     3481 ctttcaaggc ttacgctgcg acccacaaaa attgtgtctt tcttgtggat acctatgaca
     3541 cccttcgcat cggtgtacca gctgccattc aggtggcgcg tgagctgggt gatcagatta
     3601 actttatggg tgtgcggatt gactctgggg atattgccta catttctaag aaagtccgtc
     3661 agcaactgga cgaggctgga tttacagagg ctaagattta tgcttctaat gatttggacg
     3721 aaaatactat cctcaacctc aagatgcaaa aggccaagat tgatgtctgg ggcgtgggta
     3781 ccaagctgat tacagcatat gaccagccag ctcttggggc ggtttacaag attgttgcaa
     3841 tcgaagatga aactggtcag atgcgcaata cgattaagct gtctaataat gctgaaaaag
     3901 tctctacgcc aggtaagaag caggtgtggc gcattaccag tcgtgaaaaa ggtaagtcag
     3961 aaggtgacta catcacttat gatggtgtgg atattagcta catgacagaa atcaagatgt
     4021 tccatccgac ctatacatac atcaagaaga cggttcgtaa ttttgatgcc gttcctctct
     4081 tggtggatat cttcaaagaa ggaatattag tttacaactt gcctagtttg actgacattc
     4141 aggattatgc ccgtaaagaa tttgacaagt tgtgggatga gtataagcgt gtgctcaatc
     4201 cgcagcacta tccagtggat ttggcgcgtg atgtatggca agataagatg gacttgattg
     4261 ataagatgcg caaggaagcc cttggtgaag gagaagaaga atgagtttgc aagaaacgat
     4321 tatccaagag ctgggtgtca aaccagtgat tgatgcccag gaagaaatcc gtcgttctat
     4381 tgatttctta aaaagatatc tgaaaaaaca tcccttccta aaaacctttg tactagggat
     4441 ttctggggga caagactcaa ccttggcagg gcgtttggcg caattagcta tggaagaact
     4501 gcgagctgaa acgggagacg acagctacaa atttatcgct gtccgcctgc catacggagt
     4561 gcaagctgat gaagcagatg ctcaaaaagc cctagccttc atccagccag atgtcagctt
     4621 ggttgtgaat atcaaggaat cagctgatgc catgacagct gcagttgaag cgacaggtag
     4681 tcctgtttca gacttcaaca aggggaatat caaggcacgt tgccgtatga ttgctcagta
     4741 tgcccttgct ggttcccata gcggagcggt cattggaaca gaccacgccg cggaaaatat
     4801 cacaggtttc tttaccaagt ttggtgacgg cggtgcggat attctccctc tttaccgcct
     4861 caataaacgc caaggaaaac agctcttgca gaaacttggc gcagagccag ccctttatga
     4921 aaaaatccca acggcagacc tagaagaaga taaaccaggc ctagctgacg aagtcgcact
     4981 tggagtcacc tatgcagaga ttgacgatta cctagaaggc aaaacaatca gcccagaagc
     5041 tcaagcgacc attgaaaact ggtggcacaa aggccaacac aaacgccact tacccatcac
     5101 cgtatttgat gacttttggg agtaaaaacc tccattggag gtttttaccc tgagcctaga
     5161 aatgagaaag tgagagaagg tccgggggat cttgaacccc gagtttagaa ataagaaaat
     5221 gaggcagatt cggtaactcg aagagttcga tttcatcgtc ttacccctgc aacgatgact
     5281 aggtttgaaa aagcttgcta gatcgcattt caaaccaggc agcgactgcg tcaagaaatt
     5341 agaagacaaa ctcgttttct agctgttact gagttgagtc tttttactac gagcatagaa
     5401 ataaggaagt gaggtagcat catgaaatct atcggtacgc aaatattaca gacagaacgt
     5461 ttgattttaa gaagatttgt ggagagtgat gcagaagcca tgtttcaaaa ttgggcttca
     5521 tccgctgaga atttgaccta tgttacctgg gatccccatc ctgatgtcga aatcactcga
     5581 aactcgattc gcaattgggt tgcttcctat actaatctca actattacaa atgggccatt
     5641 tgtctaaaag aaaacccaga gcaagtgata ggagatatca gcatcgttaa gatagacgag
     5701 gctgatttaa gctgtgaaat cggctatgtg ctaggcaagg cttactgggg acatggtatg
     5761 atgacagagg ccttgaaagc tgtcttggac ttttgtttta ctcaagcagg ttttcaaaag
     5821 gtcagagcac gttatgccag tctcaaccca gcttcaggtc gtgtcatgga aaaggctgga
     5881 atgtcctatc tacaaaccat tgttaatggt gtagagagaa aaggctatct tgcggatctt
     5941 atttattatg gtataagtag ggaagaatgt tgaattctat tttctgtttc tatcgaagtc
     6001 aactatttat tgtaaatata ataattagca ttccaagttt atttgaaact ttaaaatagc
     6061 atattgatta gtacaagaca gatgttctag ttccttcttt aatctggttt agtattagtt
     6121 aaaaaatcgc ttgaagcttg taactaagag ggagctaatc gactaggttc tccagccgaa
     6181 caggtggtaa tgtacttttt atagtgtaat cctagctgtt gttaaattta aaatagaatc
     6241 ctctatcgag ttagggaatt aaattcaacc aattttattt atgtttttct atcaaattat
     6301 ctaatattaa aatagtctca ttctgatgag aaaactattc tatttatact gcatagttgt
     6361 ataaggaatg atgaaagatg agtgaaagtt atcaagttgg aatgtttgta tctaaatata
     6421 ttagcatgta tttagataag atgtctgcaa tcctttatat atgagattga ttacgatata
     6481 gttaaagtgt tagttcaata atcaatatat cattctaagt ctattttata tataaagtat
     6541 attgtttaac gtttgataga aaagatgcta tactagaagt aggatgtaat ggcaaaatct
     6601 aatactaata agcgctatgc aatacgtaaa ctcggaaaga tttttggttc tgcggtaatc
     6661 gggctaactt tatttttagg aggaatctga atacaagttt tgttcatgct gctgatggga
     6721 ttcaatatgt cagagatgat actagagata aagaagaggg aatagagtat gatgacgctg
     6781 acaatgggga tattattgta aaagtagcga ctaaacctaa ggtagtaacc aagaaaattt
     6841 caagtacgcg aattcgttat gaaaaagatg aaacaaaaga ccgtagtgaa aatcctgtta
     6901 caattgatgg agaggatggc tatgtaacta cgacaaggac ctacgatgtt aatccagaga
     6961 ctggttatgt taccgaacag gttactgttg atagaaaaga agccacggat acagttatca
     7021 aagttccagc taaaagcaag gttgaagaag ttcttgttcc atttgctact aaatatgaag
     7081 cagacaatga cctttctgca ggacaggagc aagagattac tctaggaaag aatgggaaaa
     7141 cagttacaac gataacttat aatgtagatg gaaagagtgg acaagtaact gagagtactt
     7201 taagtcaaaa aaaaagactc tcaaacaaga gttgttaaaa aaggaaccaa gccccaagtt
     7261 cttgtccaag aaattccaat cgaaacaaaa tatctcgatg gcccaactct tgataaaagt
     7321 caagaagtag aagaagtagg agaaattggt aaattactct tactacaatc tatactgtag
     7381 atgaacgtga tggaacaatt gaagaaacta cttctcgtca aattactaaa gagatggtaa
     7441 aaagacgtat aaggagaggg acgagagaac ctgaaaaagt tgttgttcct gagcaatcat
     7501 ctattccttc gtatcctgta tctgttacat ctaaccaagg aacagatgta gcagtagaac
     7561 cagctaaagc agttgctcca acaacagact ggaaacaaga aaatggtatg tggtattttt
     7621 ataatactga tggttccatg gcaacaggtt gggtacaagt taatggttca tggtactacc
     7681 tcaacagcaa cggttctatg aaagtcaatc aatggttcca agttggtggt aaatggtatt
     7741 atgtaaatgc atcgggtgag ttagcggtca atacaagtat agatggctat agagtcaatg
     7801 ataatggtga atgggtgcgt taacagattc ctccctgcga caaaattgat aatagtatgt
     7861 ctgaatatat aattatatat aaaaagctat agataaggtc atcttatagc gactataaaa
     7921 aagtgaacaa gcctagtctt ctgtacatta gaattcagat ttgttcactt tttgtttaat
     7981 actcaatgaa aatcaaagag caaactagaa aactagtcgc aggttgctca aagtactgct
     8041 ttgaggttgt agatagaact gacgaagtca gtcacatata taatccaagg tgacgttgac
     8101 gcggtttgaa gagatttttg aagagtataa gtctttgatt ttgagactaa ggagagtcag
     8161 ggtcaaagta gtgaatgatt ctgaaataac tcataatagt ctcttgagag gacagataag
     8221 agtaacaaat atggtgctac tcatgtgtct tgcattttga tttacaaaca gcgaagaaaa
     8281 tataggaagc tgaaataaaa tatagatgaa tcaatttgga gagtcaacgc aatctatggc
     8341 aatattttcg aagctagggg gaagcatttt aatttcaatg tactaggcct cttctacagc
     8401 tagctagagt ttcaattgta gatgttcttt gaaataatat cttagcgatt tattggtatt
     8461 agaagattta gagaaattct ttctcaataa ataaacatgg cgtcaccaaa actgaagaag
     8521 cggtagtgtt cttggatggc atggtggtag gcatctaaga ctaattcacg gcctgcaaag
     8581 gcagaaacca acatgaccag agttgatttt ggcaggtgga agttggttga gaaggcatcc
     8641 acgaccttcc actcataccc aggtttgata aagatattgg tccaaccaga atctgcttgg
     8701 atttgcccat caaacttgga accaatagtt tccaaggtgc ggatagaagt ggttccgaca
     8761 gcgatgacac gaccaccatt ttctttgaca gagcgaaggg tggcagcagc ttcctcagaa
     8821 agttgataga actctgagtg catttcgtgt tcgtccagat tatccacaga aacaggtcta
     8881 aaggttccga gtccgacatg gagagtcaga tagactagat gaacaccctt agcttggatt
     8941 tctgccagca gttctttggt gaagtgaaga ccagcagtcg gtgctgcagc agagccgctt
     9001 tccttggcgt agacggtttg ataacgttca cggtcatcta atttttcgtg gatataaggt
     9061 ggcagaggca tttctcccag actttccaag acttctagga aaattccttg gtattcaaag
     9121 cggacaatgc gtcccccgtg ggtcaattct tctgtaacga cagcgctgag gcggccatca
     9181 ccaaagctga tacgagtacc gaccttgagg cgtttggcag gtttagccag aacttcccac
     9241 tcgtctccac tagtgttctt aaggaggaga agttccacat gacctcctgt ctccactttt
     9301 tgaccataga ggcgggcagg gagaactcgg gtgtcgttca tgacaagggc atcaccaggt
     9361 tccagcatat caataataga gtggaagtgt ttatcttgca tttctcctgt ctcacggttg
     9421 acgatgagga gtttggaggc atcacgtttt tcaaggggcg tttgggcaat caattcctct
     9481 ggcaagtgga aatcaaaatc agctgtattc atatatttgt tcattctttc taagttctaa
     9541 tcctatccat tataacacgt ttcaagtttg gacgctcttt ttttagaaat taaatcgttt
     9601 tcacttgaca aaaattggtc tataccatat aataaatata gacagaaatg gaggatgaaa
     9661 agatgaaagt tattaaagtt gaaaaccaag ttcaaggtgg aaaagttgct tttgagattt
     9721 tgaaggaaaa attggctaat ggagctcaaa ctctaggact tgcgacagga agtagcccac
     9781 ttgaatttta caaggaaatt gttgagagtg accttgattt ttcaaatcta accagtgtca
     9841 accttgatga gtatgtgggc cttgatgggg acaatccaca gtcttatcgt tacttcatgc
     9901 aagaaaactt gttcaaccaa aaaccattta aagaaagttt cttgcctcgt ggtgttaagg
     9961 acaatgctga agctgaagtt gaacgctaca accaaatttt ggctgaccat ccagttgacc
    10021 tccaaatctt gggaatcggt cgcaatgggc atatcggctt taatgagcct ggtactccat
    10081 ttgacagtca aacgcatcta gtagaacttg accagtctac tatcgaagcc aatgcacgct
    10141 tctttgccaa gattgaagac gtcccaaccc aagctatttc aatggggatt aaaaacattt
    10201 tggatgccaa gtctattatt ctttttgctt acggtgagtc gaaagcagaa gccattgccg
    10261 gaacagtatc tggcccagtg actgagaacc tacctgcaag tagcctccaa aatcaccctg
    10321 atgtaaccat catcgcagat gctgaagcgc ttagcttact cgaaaaataa aaagtataag
    10381 aaccgcttgc tctttggagt gagtggtttt agacatataa aacttcaact taactttagg
    10441 aggacacatg aataaagaag aatttttaaa aataaaagaa gcatataaga gtgctagaac
    10501 ggaagaaaga aaaagtataa taggcttcat tacaaaaaag aaagataagg aggggaattt
    10561 tctttttact aagtcaaaag ataaaccata taccacaaga aatcaatatt caggaggcgg
    10621 aggaaataaa aagtacacct cgggtagtag attatctagg ccatatgatt tatcaaatca
    10681 catgtggatt gatttgtcat ataaaggaaa tgacatctta atctctttac agtcttttga
    10741 tattgatcca aatagtaaag aacttcacgt cttatatgat agaataggca tcttatttga
    10801 acaatctaaa aaaattccaa tttttaaaga ttgctataca ataactaaag tcagtgatgc
    10861 ttttcttaaa atggaaacaa caaactggga attaccttta tctaaagcag atatggaaga
    10921 gatggtgaac tatattatta atcattatga agaataaaaa acttagtttc ctcttgacaa
    10981 ttattccttt tacgtgtaga atgaaataga tattgaactt gaagggagtg aaaaaaatgt
    11041 ctaaaacagt agtacgtaag aatgaatctc ttgacgacgc acttcgccgt ttcaaacgtg
    11101 cggttactaa agctggtact cttcaagaaa cacgcaaacg tgaattctat gaaaaacctt
    11161 ctgtaaaacg taaacgtaaa tcagaagtag ctcgtaaacg taaaaaattc taattgaaat
    11221 gaaaggctag agaaatctag tcctttttct tttaaataaa tactccaaag cctgcaaaaa
    11281 tctgaaactt cctcctacaa tttgatataa tagagagaag aactcatttg aaggaggaaa
    11341 tgatgtcggt tttagtaaaa gaagtgattg aaaagcttag actagacatt gtctatggtg
    11401 aaccagaatt gcttgaaaag gaaatcaata tagcggatat tacgcgacct ggtcttgaaa
    11461 tgacaggcta ttttgactac tatacaccag agcggattca acttttgggg atgaaggagt
    11521 ggtcttatct gatcagcatg ccttccaaca gccgttatga agttttgaaa aaaatgtttc
    11581 tacctgagac accagcagtc attgttgccc gtggtttggt ggttccagag gagatgttaa
    11641 aggctgctag agaatgtaag attgctattt taaccagccg tgcagctacc agtcgtttat
    11701 ctggagagtt atctagctat ctggattctc gtttggcaga acgtaccagt gtgcacggtg
    11761 tcttgatgga tatttatggg atgggcgtct tgattcaggg agatagtgga attggtaaga
    11821 gtgagacagg tcttgagctt gtcaaacgtg gtcaccgttt ggtagccgat gaccgtgtcg
    11881 atatctttgc caaggatgag attactctct ggggtgaacc agctgaaatt ttgaaacact
    11941 tgattgaaat tcgtggggtt ggtattatcg atgttatgag tctctacggt gcgagtgctg
    12001 tcaaggattc ttcacaggtt cagcttgctg tctatttgga aaattacgat acgcataaga
    12061 cctttgatcg tcttggaaac aatgcagagg aacttgaagt ttctggcgta gccattcctc
    12121 gtattcgtat tccagttaaa acaggtcgta atatctctgt tgtgattgag gcagctgcca
    12181 tgaattatcg tgccaaggaa atgggctttg atgcgacccg tttgttcgac gaacgactga
    12241 caagtctcat cgctcgaaat gaggtgcaaa atgcttgatc caattgctat tcaactagga
    12301 cccctagcca ttcgttggta tgccttatgt attgtgacag gcttgattct tgcggtttat
    12361 ttgaccatga aagaagcacc tagaaagaag atcataccag acgatatttt agattttatc
    12421 ttagtagcct ttcccttggc tattttagga gctcgtctct actatgttat tttccgattt
    12481 gattactata gtcagaattt aggagagatt tttgccattt ggaatggtgg tttggccatt
    12541 tacggtggtt tgataactgg ggctcttgtg ctctatatct ttgctgaccg taaactcatc
    12601 aatacttggg attttctaga tattgcggcg cctagcgtta tgattgctca aagtttgggg
    12661 cgttggggta atttctttaa ccaagaagct tatggtgcaa cagtggataa tctggattat
    12721 ctacctggct ttatccgtga ccagatgtat attgagggga gctaccgtca accgactttc
    12781 ctttatgagt ctctatggaa tctgcttggc tttgccttga ttctgatttt tagacggaaa
    12841 tggaagagtc tcagacgagg tcatatcacg gccttttact tgatttggta tggtttcggt
    12901 cgtatggtca tcgaaggtat gcgaacagat agtctcatgt tcttcggact tcgagtgtcc
    12961 caatggctgt cagttgtcct tatcggtctc ggtataatga tcgttattta tcaaaatcga
    13021 aagaaggccc cttactatat tacagaggag gaaaactaaa tgttagaagt tgcatatatt
    13081 cttgttgcct tagctttgat tgtctttttg gtctatctga tcattactgt acaaaagctt
    13141 ggtcgtgtca tcgatgaaac agaaaagacg attaaaacct tgacttcaga tgtggatgtg
    13201 accttgcatc acaccaatga gttgttggct aaggtcaatg tcttggcaga tgatatcaat
    13261 gtcaaggtgg ctacgattga tccactcttc agtgctgttg cagatttatc tctatctgtt
    13321 tcagacctca atgaccatgc gcgtgtcttg agcaagaaag cttcatcagc tggttcaaaa
    13381 acactcaaga ctggtgcaag tctgtcagct cttcgtcttg caagtaaatt tttcaaaaaa
    13441 taaaaaagga gaatccttat gggtaaatta tcctcaatcc ttttaggaac ggtttcaggt
    13501 gcagctcttg ccttgttttt aacaagtgat aagggcaaac aagtttgcag tcaggctcaa
    13561 gattttctag atgatttgag agaagatccg gagtatgcca aggagcaagt ctgtgaaaaa
    13621 ctgacagaag ttaaggagca ggctacagat tttgttctga aaacaaaaga acaggttgag
    13681 tcaggtgaaa tcactgtgga cagtatactt gctcaagcta aatcctatgc ttttcaagcg
    13741 acagaagcat caaaaaatca attaaataat ctcaaggaac aatggcaaga aaaagccgaa
    13801 gctcttgatg actcagaaga gattgtgatt catataacag aagaataaac catcaccatc
    13861 tccggacgga ctatgtatct ggggatggtg atttttatct ggaatctagt ctttgtggta
    13921 taataattac tatgcagaaa aaaccaacgt cagcctatgt gcacatccca ttttgtaccc
    13981 agatttgtta ttattgtgat ttttcaaagg tcttcatcaa aaatcagcca gtcgacagct
    14041 atttagagca tctgctggaa gagtttcgtt cttatgatat tgaaaagttg tcaacccttt
    14101 atatcggtgg tggaacaccg acagccctgt cggctccgca actggaggtg ttactgaatg
    14161 gcttgactaa aaacttggat ttgtctgtct tggaagagtt gaccattgaa gccaatccag
    14221 gcgatttgga tgcggataag atagctgttt tgaaaaattc ggctgtcaat cgtgtttcgc
    14281 taggtgtcca gacctttgat gataagatgt tgaaaaagat tgggcgcagt catttggaga
    14341 aggatattta tgaaaatatc gatcgcctga aactggctgg ttttgacaac atctccattg
    14401 atttgattta tgctctgcct ggtcagacca tggagcaagt aaaggaaaat gtggctaaag
    14461 ccattggatt ggatattccc cacatgagtt tgtatagttt gattttagaa aaccatacgg
    14521 tctttatgaa ccggatgcga cgtgggaaat tgcctctgcc taaggaggaa ctagaagcgg
    14581 agatgtttga gtacatcatt gcagagctgg agcgagcggg ttttgagcat tatgagattt
    14641 ctaatttctc caaacccggt tttgaaagtc gtcataatct catgtactgg gacaatgctg
    14701 aatactatgg tattggtgca ggggcatctg gttatgtcaa tggagtacgc tataaaaatc
    14761 atggtcccat tcgtcattat ctcagtgcgg ttgaggaagg caatgcttgt attacagaag
    14821 atcacctgag tcaaaaggag caaatggaag aagaaatgtt cttgggactc cgcaagaaat
    14881 ccggggtttc catggcgcga tttgaggaaa aatttggaca gtcttttgct ggactttatg
    14941 gagaaattgt cagagatttg gttcaacaag gcctcatgca gattgagggt gaccacgttc
    15001 gcatgacaaa gagaggtctc tttttgggag atactgtagc agaacgattt attttggagt
    15061 aggatcatgg gcttaactta tcaaatgaaa atgaaaattc cttttgatat ggctgatatg
    15121 aacggtcata tcaaacttcc agatgtgatt ttgctgtcac tgcaagtttc agggatgcaa
    15181 tcgattgaac tgggagttag tgataaggcc attttggaag actataatct ggtctggatt
    15241 atcgcagaat atgatattga ggtggttcgt ttgcctcgtt ttgcggaaga aattaccatc
    15301 gaaacggaag ccttgagcta caatcgactt ttttgctacc gtcgctttac tatttataat
    15361 gaagcggggc aggagctcat ccatatgatg gcgacctttg ttctcatgga ccgcgacagt
    15421 cgaaaagtcc atgctgttga acctgagatt gtggctcctt accagtctga ttttgataaa
    15481 aaacttatcc gtggaccgaa gtatgaatcc ttggaagagc cgatcagcaa ggattaccat
    15541 gttcgttttt acgacttgga tatgaatggt catgtcaata acagtaaata cttggactgg
    15601 atttttgagg tcatgggagc ggattttttg acccactata ttcccaagaa aatcaacctc
    15661 aagtatgtca aggaagttcg accaggtggg gtgattacat cggctgttga acggactgga
    15721 ctggaaagca agcatgaaat tacaagtgat ggggttatca atgcccaagc aatcattact
    15781 tggcaagaaa taaaaaaggt ttagggagaa atagatgaaa tataaaggct atttaatcga
    15841 tttagacgga accatttata aggggaaaga ccgaatccct gctggagaga cttttgttca
    15901 tgaattgcaa aagcgggaca ttccctatct ctttgtaacc aacaatacaa cccgcactcc
    15961 agagagtgtt aaggagatgt tggctcagaa ttttaatatc gatacgcctc tatcgactgt
    16021 ctacacagcg actttggcaa ccatcgacta tatgaatgat ttggggcttg aaaagaccgt
    16081 ctatgtcgtc ggagaagcag gactcaagga agccatcaag gcggctggtt atgtggaaga
    16141 caaggaaaac cctgcctacg tggtagttgg tctggattgg caagtcgact atgaaaaatt
    16201 tgccacagca actcttgcta ttcaaaaggg tgcccatttt atcggaacca atcctgacct
    16261 caacatcccg acggaacgtg gtcttttgcc aggtgctggc tcactgatta cgctgcttga
    16321 agtagcgaca cgagtgaagc cggtttatat cggaaaacca aatgccatca ttatggacaa
    16381 ggcggttgag cacttaggtt tggaacgtga agagttaatc atggttgggg acaattattt
    16441 gactgatatc cgggctggga ttgacaatgg cattccaaca ctcttggtga cgacaggttt
    16501 taccaaggca gaagaagtag ctggcctgcc aatcgcaccg acacatgtgg tttctagcct
    16561 tgcggagtgg gattttgatg aaaactaaat tgaccttttg gggctctatg ctctttctcc
    16621 tctccctctc aatccttctg accatttatc tggcttggat tttctatcct atggagattc
    16681 agtggctaaa cttaacgaat cgagtctatc taaaaccaga aaccattcaa tacaattttc
    16741 atatcttgat gaattatctg accaatcctt ttagtcaggt cttacagatg cctgattttc
    16801 gttcgtcagc agctggtctg caccatttcg cagtggtcaa gaatctcttt catttggttc
    16861 agctagtagc tctagtgaca ctgccaagtt tctatgtctt tgtcaatagg attgtgaaaa
    16921 aggacttttt gtctctttat cgaaaaagtc tcctgactct agtagtctta cctgtgatga
    16981 ttggacttgg gggagttttg attggttttg accaattctt tactcttttc catcaaattc
    17041 tctttgtggg agatgatacc tggctttttg atccagccaa ggatcctgtt attatgattt
    17101 tgccagagac cttctttctt catgccttcc tcctcttttt tgccctctat gaaagcttct
    17161 ttgggtatct gtgtctgaaa agtcgtagga agtgaaatga aagatgtttt taatttgcat
    17221 atataaaaat atatatcgtt taaaaccatc gttaagagtg aattaaccaa atccaattgt
    17281 gtcaatcgtt cgcaaacagc ctatttttct tgaaaaaata ggcttttttt ctaaaaatcc
    17341 ctagtcaagc gccttatttt tttgtataat agaagtagca aagtatagat aagaagagaa
    17401 aagcatgatt acactatttc tatcaccgag ctgtacatca tgtcgtaagg ctaaggcctg
    17461 gttagaaaaa cataaggttc cctttgtgga acacaatatt atgaccagtc ctttaacaag
    17521 aaaagaattg caacacatcc tttccttgac cgaaaatggt actgatgaca tcatttcaac
    17581 tcgttcaaaa atttttcaaa aattgaatat tgatgtagag agtatttcgg tatcggaatt
    17641 gcttcatttg attgagcagt atcctagtct tttgcgtcgt ccaattatta ttgatgccaa
    17701 gcgtatgcaa atcggtttta atgaagatga gattcgtgct tttctccctc gtagttatcg
    17761 taagcaagaa ctaaaagaag caagaatgag agctggtatt agttaatgaa caaacagtat
    17821 agttacccac tagatttgtc gtggagcact gaagaacttg cttcagtgct ttcttttttt
    17881 aatgatgttg aagctgccta tgaaggcaaa gtagaggcta aaaagttact ggactcctat
    17941 aagggattca aagcggtcgt gccaagcaag agcgaagaga aacgtttggg acgagaattt
    18001 gaaacggtta gtggctattc actttaccga gcagttcagg ctgccaaaga aaaaggggaa
    18061 ggaaagattt ctcttggaaa gtaaatttga atttgctaaa gagcttgtta agaaagcagg
    18121 ccagtacatt cttgaccata tgcaggaaga cttgcgtgtt gaaaccaagt cctcttcaac
    18181 agatttggtg accagactgg acaaagaagt tcaggaactc ttggttggtg agattttgtc
    18241 ccgttatcct gaggataaga tttgtgctga agaaggttgt ctgcgagcct cggttcaaga
    18301 gggcaaggtt tgggtcattg atcccattga tggtaccaat aattttgtag cccagcagga
    18361 agattttgct gttatgatgg cttattttga aaatggtcag ggacagtttg gtctgattta
    18421 tgatgtggtc aaaggggatt gttaccacgg tggtggggaa tttccagttt gtctaaatga
    18481 taggccccta gctcctttta aaactaaacc acttggagat tttctcattg cagggaatag
    18541 tggtatgctg gaaaccaatg aatgggggct ggctgatttg agccgatcgg ttcttggtgt
    18601 tcgtgtctat ggaagtgcgg ccattagttt tgccaagatt ttgtcagggc gtttgttgac
    18661 ctatctcact tatctgcaac catgggatta tgccgcagct agtattttag gggaaagtct
    18721 gggctatcgg gttgtgaccc tttttggtga agctcctgat tttcaaacca gacagccggt
    18781 catgatggtg cctcttgaga tgcaggagga aattcagtcc tatatttacg aaaggaaaag
    18841 aacttaaatg caatttccag aaggatttgt tgaaaaatat aaagagatac taggagatga
    18901 ggcaagagat tttcttgcct cttttgagga ggaagcggtt tcggcctttc gggtcaatcc
    18961 cttaaaagaa gagcaacttt ccttttctga tgccattact caaacccctt ggggccacta
    19021 tgggaaggtt tcagggaaat cgcctgagca tgctacaggt ttagtttatt cgcaagaacc
    19081 tgctgctcaa atggtggctc aagtagccca acccagtcct ggtatgaagg tcttggactt
    19141 ggctgctgca ccggggggca aatcaactca actggcagcc tatctagcag gtgaggggct
    19201 acttgtttcc aatgaaattt caagcaaacg ggctaagatt ttggttgaaa acatggagcg
    19261 ttttggagcg acaaatgtcg tggtgaccaa tgaatctgcc gaccgcttgg tcaaggtctt
    19321 taaaggctat tttgacttaa tcgttcttga tgccccttgc tctggtgaag gaatgtttcg
    19381 taagcaacct gatgctatgg actattggag cttagattat ccgagtcaat gtgctagctt
    19441 gcaaagagaa attctggagg atgcagtgac catgttagct gaaggtggtc gtctggttta
    19501 ttcgacctgt acctgggcac ccgaggaaaa cgaagagatt gtcaattggt tgctggaaga
    19561 gtatgatttt gacttgttgc cagtagagca tatcaatgga atggtagctg gtattgacct
    19621 gccagaaacg gctcggatgt accctcatca gtttaaggga gagggtcagt ttgttgccca
    19681 tctacagttt aagggtaaca atccagctcc taaatttaag gcaagtaaga gtaacctcag
    19741 ccgtgaacaa gttgccttgt ggcaggaatt tgcccaaaac catttgaagg tcaatctacc
    19801 gggtatcttg cagacttttg gagaccagct ttatctcttg ccagaacttt tgccagattt
    19861 agggaagctc aagattgctc gcaatggact gcatctgggc acttttaaga agaaacgctt
    19921 tgagcccagt ttcgctcttg gtttagcctt gaaaccgagt caggtcgaac agtcggttga
    19981 aattggccaa gaagcgtttg tcaagtatgc ggctggagaa accgttcagc tggcagaaag
    20041 tctgccaaat ggttggtacc aagttttggt taaaggcaat ggcttgggct ttgcaaaggt
    20101 tactggaaat gttttgaaaa attattttcc aaaaggcctc agattcaaat gaaaatgcta
    20161 gtcaaatatc ttattctatg ttatagtgaa agtatggatt tttttagtag gatgattctt
    20221 gatatcttga ttgccatcac atgtagtttt actactcgat gaaaatcaaa gagcaaacta
    20281 ggaagctagc catagatagc tcaaaacact ggtttgaaga gattttcaaa gagtacaaga
    20341 agtttagtta ttagcgttct taccgcttgt aaactagatt tctcataaaa tagaatcttt
    20401 tccttttagt tgtaaactag tctgggagag tagagaggtt tgagatacct ttctagcttt
    20461 tggattatca tctgaggaga gtaatttccc ttgcattaaa aaggggaaaa agagacacga
    20521 aatgattata atgggtgaca atgggggaag ggatagacaa gagattttat ccacatatga
    20581 aaaaaggagg ttaggaaaga gtaatatagc ctatattata taaataatca attgcgcaga
    20641 aatttggtaa gaattcatgc gtcaactcat aaagaactac ttaaaaaatt cacagtattc
    20701 ataattattt tcgaggagaa aaacagtgaa aaaaagaaaa aagcttgctc tgtctcttat
    20761 cgctttttgg ctgacggctt gtttagtagg ctgtgctagc tggattgatc gtggagaatc
    20821 cataacggct gttggctcaa ctgccttgca acccttggtt gaagtagcgg cagatgaatt
    20881 tggcacgatc catgttggaa aaacggtcaa tgtccaaggg ggaggttctg gtacaggctt
    20941 gtcccaggtt cagtctgggg cagttgatat aggaaactca gatgtatttg ctgaggaaaa
    21001 agacggaatt gatgcttctg ctcttgttga ccacaaggtc gcggtagctg gcttggctct
    21061 gattgtcaat aaggaggttg atgttgataa cctaacgaca gagcaacttc gtcaaatctt
    21121 cataggtgag gtaaccaatt ggaaagaggt tggtggtaag gacttaccca tctctgttat
    21181 caatcgggca gccggctctg gttctcgtgc tacctttgat actgtcatta tggaaggtca
    21241 gtctgccatg caaagtcagg agcaggattc aaatggagcg gtaaaatcaa tcgtatcaaa
    21301 aagtccagga gctatctctt atttatctct tacctatata gatgattcgg tcaaaagcat
    21361 gaagttgaat ggctatgact taagtccaga aaatataagt agcaataatt ggcccttgtg
    21421 gtcttatgag catatgtata cattggggca gcccaatgag ttggctgcag aatttctcaa
    21481 ttttgttctc tcggatgaga cccaagaagg gattgtcaaa ggattgaagt atattccgat
    21541 taaggaaatg aaggttgaaa aagatgctgc cggaactgtg acagtgttgg aagggagaca
    21601 ataatgaatc aagaagaatt agctaagaaa atgttgcttc catcaaagaa ttctcgtctg
    21661 gagaaattag gaaaaggttt gacctttgcc tgtctttctt tgatagtcat ccttgtggcc
    21721 atgattttgg ttttcgtagc gcaaaaaggc ttgtcgacct tctttgtcaa tggtgtgaat
    21781 atctttgact ttcttttggg aggaacttgg aatccttcta gtaaagaatt tggtgccctt
    21841 cctatgattt tgggttcctt tatcgttacc attctctcag cccttatcgc aacacccttt
    21901 gctattggtg cagcagtttt tatgaccgaa gtatcaccaa aaggggcgaa gattttgcaa
    21961 ccagctattg aactcctggt tgggattcct tcagtagtgt atggatttat tggcttgcaa
    22021 gtcgtcgttc cctttgttcg cagtgtcttt ggtgggactg gttttgggat tttgtcaggg
    22081 atttccgtcc tctttgtcat gattttgccg accgtaacct ttatgacaac ggatagcttg
    22141 cgtgcggttc ctcgttatta tcgtgaagcc agtttcgcta tgggagccac tcgctggcag
    22201 actatctggc gtgtgatctt gaaggcggcc cgttctggta ttttcactgc agtggtcttt
    22261 gggatggcgc gtgcctttgg tgaggcttta gctatccaga tggttgtcgg aaactcagct
    22321 gttatcccaa cttccttgac cacaccagct gcaactttaa cttctatatt aactatggga
    22381 attgggaaca ctgtcatggg aactgtaaat aataatgttc tctggtcact ggccttggta
    22441 ctgctcttga tgagtttagt ttttaacagt gtgattaaat tgattacgaa agaaagagga
    22501 aagaaaaatt atgcgcgcta agaaattaga taaacttgca acagctgtcc tctatacgat
    22561 tgctagcatc attgtgacaa tcttggcttc cttgattctc tatatcttgg ttcggggctt
    22621 gccccatatc tcttggtctt tcttgactgg aaggtcttct gcttttcaag caggtggtgg
    22681 gattggcatt cagctttaca attccttttt cctattggtc attaccttga ttatttctgt
    22741 acctctttct atgggagctg ggatttactt ggctgaatat gctaaaaaag gtcctgttac
    22801 caactttgtg cggacttgta ttgaaatctt gtcctcttta ccatcagtgg tggtgggtct
    22861 ctttggttac ttgatctttg tagtccagtt tgagtatgga ttttcaatca tttcaggtgc
    22921 cttggccttg acagtcttta acttgcctca gatgacgcgt aatgtagagg atagtttgaa
    22981 acacgttcac catacccaac gtgaggctgg tctggctctt gggatttctc gctgggagac
    23041 agtggttcat gttgttattc cagaagcgct tccaggtatt gtaacgggtg tcgtcttggc
    23101 atctggtcgt atctttggcg aagctgcagc tctgatctat acagcagggc aatcggcgcc
    23161 agctcttgac tggtctaact ggaatatcct cagtgtgact agccccatct ctatcttccg
    23221 tcaagcagaa accttggctg tccatatctg gaaagtcaat agtgaaggca ctattccaga
    23281 tggaaccatt gtatcagcag gttctgccgc tgtgctcctg atctttatcc tgatttttaa
    23341 ctttggagct cgtaagttcg gaagctatct acacaagaaa ttaaccgctg cctaaaggag
    23401 aagccatgtc aacatataac tgggatgaga agcatatcct tacctttcct gaagaaaaag
    23461 tagccctttc tactaaggat gtccatgttt actatggtaa aaatgaatcc attaagggga
    23521 ttgatatgca atttgaaaga aataaaatta cagctttgat tggtccgtcg ggatcgggga
    23581 aatctaccta cttacgcagt ctcaatcgca tgaatgatac cattgatatt gctaaagtaa
    23641 ctgggcagat tctctatcgt ggaattgatg tcaaccgtcc agaaatcaac gtttatgaaa
    23701 tgcgtaaaca cattggaatg gtttttcaac gccccaatcc atttgctaag tcaatttacc
    23761 gtaatattac ctttgcgcat gaacgtgctg gagttaagga taagcaagtc ctagatgaaa
    23821 tcgtagaaac ctcccttcgt caggctgccc tctgggatca ggttaaagac gatctccaca
    23881 agtcagcctt gaccttatca ggtggtcagc aacaacgtct ctgtatcgct cgtgccatct
    23941 ctgttaagcc agatatcctc ttaatggatg agccagcttc agccttggat ccgattgcga
    24001 ccatgcaact agaagagacc atgtttgagc tcaagaaaga ctttaccatc atcattgtaa
    24061 cgcataatat gcagcaggct gctcgtgcaa gtgactatac aggcttcttt tacttgggtg
    24121 atttgattga gtatgacaag actgcaacta ttttccaaaa tgccaagcta cagtccacca
    24181 atgactatgt atctggtcac tttggttaga aaggaaaccg tatgacagat gcgattttac
    24241 aggtatcaga cctgtccgtt tattataata aaaagaaggc tttgaatagt gtttccctat
    24301 ctttccaacc taaggaaatt acagccttga ttggtccatc tggatcaggg aagtcaaccc
    24361 tcctcaagtc tctcaaccgc atgggagatc tcaatccaga ggtgaccaca actggatccg
    24421 tggtgtacaa tggtcacaac atctacagtc cgcgtacaga tacggttgaa ttacgtaagg
    24481 aaatcggaat ggttttccaa caacctaatc ctttccctat gactatctat gagaatgttg
    24541 tctacgggct tcgtatcaat ggaattaagg ataagcaggt tctggatgaa gccgtagaaa
    24601 aagccttgca aggtgcctct atctgggatg aggtcaagga tcgtctatat gattcagcta
    24661 ttggattgtc aggtggtcaa cagcagcgtg tctgcgtggc ccgtgtcttg gcaactagtc
    24721 ctaaaatcat cctcttggat gagccaactt cggctttgga tccgatttca gctggtaaaa
    24781 ttgaggaaac cttgtatggt ctaaaagaca agtacaccat gcttctggta acccgttcca
    24841 tgcagcaagc ttcacgtatc tctgataaga caggattttt cctagatgga gatttgattg
    24901 aatttaatga taccaagcag atgttccttg atccccaaca caaggaaacg gaagactata
    24961 ttacaggaaa atttggataa ggagatgaaa gatgttacga tctcaatttg aagaagattt
    25021 agagaaatta cataaccagt tctacgctat gggacaagaa gtgctctcac aaatcaatcg
    25081 tacggtacgt gcttttgtca cgcatgaccg tgacctggca aaagaggtca tcgaagatga
    25141 tgcagaagta aatgaatacg aagtgaaact ggaaaagaaa tcatttgaaa tgatcgcact
    25201 ccaacaacca gtctctcaag atttgcgtac agtcttgact gtccttaagg ctgtatcaga
    25261 tgtggagcgt atgggggatc acgctgtagc cattgcccag gcaaccatcc gtatgaaggg
    25321 ggaagaacgc atcccagctg tagaggaaga aattaaaaaa atgggacgtg aagttaaaag
    25381 cgttgttgaa gcagcacttg atctttatct taatggttct gttgacgacg cataccgggt
    25441 ggcctccatg gatgagcaaa ttaaccacta ttttgaaact atccgtgacc ttgcgactga
    25501 agagattaag aaaaatccag aagccattgt tacgggtcgt gattatttcc aagttatttc
    25561 ctacttggag cgtatcggtg actatgctaa aaatatctgt gaatgggttg tctactttga
    25621 aacaggtaag attgtcgaac tataaaatag tttaattctg tataaaaagg agcttgaaat
    25681 caactgatgg ctcctttttt tgaacgaaaa catatttttg agataaaaat ttaaaaaaca
    25741 cttgacaagt aacttggata tcgttataat tatacaaaat taacagagag gttgtttatt
    25801 tatgaaatca aaaaaatgga tatttgtttt atgtaatttt cttgcaagtt tcttcttagt
    25861 agcttgccag tcaggttcta atggttctca gtcagctgtt gaggccatta agcaaaaggg
    25921 gaaattagtt gtggcaacca gtcctgacta tgcacccttt gaatttcaat cattggttga
    25981 tggaaagaac caggtagtcg gtgcagacat cgacatggct caggctatcg ctgatgaact
    26041 tggggttaag ttggaaatct caagcatgag ttttgacaat gttttgacca gtcttcaaac
    26101 tggtaaggct gacctagcag ttgcaggaat tagtgctact gacgagagaa aagaagtctt
    26161 tgatttttca atcccatact atgaaaacaa gattagtttc ttggttcgta aggctgatgt
    26221 ggaaaaatac aaggatttaa ctagcctaga aagtgctaat attgcagccc aaaaagggac
    26281 tgttccagaa tcaatggtca aggaacaatt gccaaaagct caattaactt ccctaactaa
    26341 tatgggtgaa gcagtcaatg aattgcaggc tggaaaagta gatgctgttc atatggatga
    26401 gcctgttgca cttagttatg ctgctaaaaa cgctggctta gctgtcgcaa ctgtcagctt
    26461 gaagatgaag gacggcgacg ccaatgccgt tgctcttaga aaaaatagtg atgatttgaa
    26521 agaagtggta gacaaggtca tccaaaaact taagaatgaa ggaacttacc aaagctatct
    26581 tgaaaaagca gcaagtctaa ctgaagttga agaataagaa aaagcagagt tggatgtcat
    26641 tccaattctg cttttaaata gtttaaaaca ttttccagat tgtctaggga caccttggca
    26701 aattgataag gacaggtgct taaataggcc tcttcaaaga agtccaagcc cagttgactg
    26761 tgtttgagac tggcgatttt aggatactgt ctcaggtcta gcaataaacc atcgtgtagg
    26821 ggataatgag gaaggggaca aggtgtttta gttatccttt cctcgatttg tttttggtaa
    26881 gattcatgat tggtcaagcg agccaaacga tttttttcaa acaattgact gtcaatatag
    26941 agtgacaggg ccttttgcat aatgaggttg ctgtcgtagt ctaggatatt tttgtaggcc
    27001 acaaatgctt ctttgatagc atttggaaga atgagtgctg taatacgaag ggcaggaaaa
    27061 aggctggtcg agaaggactt gatataaatg acatgctcct ctgtatcaag atagtggaag
    27121 gtttggccct tcttggagtc caaatcaccc agataatcgt cctctacgat atagacatca
    27181 tacttggcag ctaagttaag aatagatcgt ttgtcttgct cagaatagga atgtcccaga
    27241 ggatagtgaa atctaggaat ggtgtagaaa aatttaattt ttcctgtttt gaagtggcct
    27301 tccagctcct ccaagtcaat cccatcaatg cctcgttcaa tcgtttgata gtccagcccc
    27361 tgtgcaatca agaggcgatt catccgatgg taggttggct gttccaccaa gatttccttg
    27421 gcttgtctag gaaaggatat ttgagagagg ataaacaagg cttgttgggt tccagaagtc
    27481 agtactagtt ggttagcctt gcagtagaga gcttgctcaa ataggagttt gtgaatggac
    27541 tgtcttaggt cttctaatcc ttcttgattg tcatagtagt tgaagaggta gttttctcgt
    27601 ccaatcaagg tttcattgac acagagtcgg aaatcgtcat aggcactggc atgttcgtcg
    27661 gtaacctcga tttctaggtc ttgatgttgc ccttgttcta atacatagta gccactctga
    27721 ggcttggcat agaggtattg ttcgtgccgt aattccagca gggctcgttg aatggtgtcc
    27781 ttgctgcagt gaaagtcaag gctcagttga cggatagaag gcaggcgact acccgtcgga
    27841 aatcgttcag actcgatacc atttttcaga taggaaacga cctctttgta cttgctttgt
    27901 ttcttcattc cagacctccc ttgattttgt tacattgtac cctttttttt ccttcttggc
    27961 aatgtctaga gcgtttctct cgttcacatc taggggcaaa tgtggtatac ttaggagtaa
    28021 gatttataga ataacagaca agaaagtgaa tggataagaa cgtgcaggaa ccagtgaaat
    28081 tatttcaata caatactctt ggagccttga tggctggcct ttatggtggt actatgacag
    28141 taggagaatt gctagaacat ggtgaccttg gtttgggaac cttggattcc attgatgggg
    28201 aattgattgt cttggatggc aaggcttatc aggccaaagg gtcaggagac cagccagaaa
    28261 ttgtggaagt gtcaccagat gcccttattc cttacgctgc agtggtaccg catcaggcag
    28321 aggtcatttt ccgccagcgc tttgagatga cagacaagga attgaaagaa cgaattgagt
    28381 cttattatga tggggaaaat cttttccgct ctatcaagat tcggggggaa ttttcacata
    28441 tgcatgtgcg tatgattcct aagtcaacac ccgataccaa gtttgctgat gtcgcaaccc
    28501 atcaaccgga atatagtcgt gacaatgttg cggggactat tgttggtttc tggacgcctg
    28561 agattttcca tggggtcagt gtggcaggct accatctgca cttcatatca gatgatttga
    28621 ccttcggtgg acatgtcatg gattttgtca tcaaggaagg cattatcgag gtgggagcag
    28681 ttgaccagtt ggaccaacgt ttcccagtcc aagaccgtca atacttgttt gctaagttca
    28741 atgttgacga gatgaaaaaa gatattgaaa aggcagaata ggagaagaaa atgaccattc
    28801 atatcattat taccatgttg ctgttgctag cttttctgat aggaagcatt tggtttgcca
    28861 aaaagaaata ccagattaat ctagctgtct tgggcttggg tgcagtcgct ttctttgtct
    28921 cttcgcagat tttggaaaaa ctggtgcata tcttgatttt gcatcctcaa aaagacggta
    28981 gtattgccct cttgcaagat catccgctta tctatattat ctatggccta gccatggcag
    29041 cattttttga ggaaacggct cgtcttgttt tcttcaaatg gttggagaaa aagagaagtt
    29101 tggaaaaggc agatgccttg gcctatggcc tagggcatgg tggcttggag ttgatttttc
    29161 taggccttat tagtttactc aatctttaca tcgttctttc ggcagttcaa actcagaatc
    29221 cacaggttat gcaattactg tctgaaaata tgttaaaaac cattcagtca ctttcggtct
    29281 ggcagattta tttgcttggt tttgagcgaa tcttggcgct tggtttccaa ttacttttga
    29341 cagtttgggt ttaccaagct gttcgccaga agaaatggat ttatctccta gcagcctatg
    29401 gcttgcatgc cttctttgat ctggcaccat ctcttttcca agtaggctgg ttgacaaatc
    29461 cagtcttggt tgaagtgatt ctagcactgg agctcgttct ggtcgcctat ggaaccaagg
    29521 aaatcttttg taaaaaatca taaaaagggg ggaacctctt tttcttatgc aaaatccaaa
    29581 caaggtattt ttatggtcgt caaatgtctc taaaaatggt ataatggaat gaattttgta
    29641 aaaggaagag tgacatgtct gtaagagaaa aaatgcttga aatcttagaa ggaattgata
    29701 tccgttttaa ggaacccttg catagctata gttatacaaa agtaggtgga gaggctgatt
    29761 atttggtctt tccacgaaat cgttttgagt tggctcgcgt tgtgaaattt gccaaccaag
    29821 aaaatatccc ttggatggtt cttggcaatg caagcaatat catcgttcgt gatggtggga
    29881 ttcgtggatt tgtcatcttg tgtgacaagc tcaataacgt ttctgttgat ggctatacca
    29941 ttgaagcaga agctggggct aacttgattg aaacaactcg cattgccctc cgtcatagtt
    30001 taactggctt tgagtttgct tgtggtattc caggaagcgt tggcggtgct gtctttatga
    30061 atgcgggtgc ctatggtggc gagattgctc acatcttgca gtcttgtaag gtcttgacca
    30121 aggatggaga aatcgaaacc ctgtctgcta aagacttggc ttttggttac cgccattcag
    30181 ctattcagga gtctggtgca gttgtcttgt cagttaaatt tgccctagct ccaggaaccc
    30241 atcaggttat caagcaggaa atggaccgct tgacgcacct acgtgaactc aagcaacctt
    30301 tggaataccc atcttgtggc tcggtcttta agcgtccagt cgggcatttt gcaggtcagt
    30361 taatttcaga agctggcttg aaaggctatc gtatcggtgg cgtagaagtg tcagaaaagc
    30421 atgcaggatt tatgatcaat gtcgcagatg gaacggccaa agactacgag gacttgatcc
    30481 aatcggttat cgaaaaagtc aaggaacact caggtattac gcttgaaaga gaagtccgga
    30541 tcttgggtga aagcctatcg gtagcgaaga tgtatgcagg tggttttact ccctgcaaga
    30601 ggtagtgggg acctgacaga gccccgatcg gttaatctat gaaaaagaag gaatttatgc
    30661 caattgaaaa aaccaattat cgaattcaaa aacgtctcta aagtttttga agacagcaac
    30721 accaaggttc tcaaagacat caactttgag ttggaagaag ggaaattcta cacccttcta
    30781 ggtgcatctg gttcggggaa atcaactatc ctaaacatta ttgcaggttt actggatgcg
    30841 acgacaggag atatcatgct agacggtgtt cgtatcaatg atattccaac caacaagcgc
    30901 gacgtacata ccgtcttcca atcctatgcc ttgttcccac atatgaatgt gtttgaaaat
    30961 gttgcctttc cacttcgctt gcgtaaaatt gataagaaag aaattgagca gcgtgtagcg
    31021 gaagttctca agatggttca gttggaaggt tatgaaaaac gttccatccg caaactttct
    31081 ggaggacaac gtcagcgtgt ggccatcgcc cgtgctatca tcaaccaacc ccgtgtggtc
    31141 ttgttggacg agcctttatc agcgctggac ttgaaattga gaacagacat gcagtacgaa
    31201 ttgcgtgaat tacaacaacg attgggcatt acctttgtct ttgtcactca cgatcaggaa
    31261 gaagctcttg ccatgagtga ctggattttc gttatgaatg atggcgagat tgtccagtct
    31321 ggaacccctg tggacatcta cgatgagcca atcaaccact ttgttgccac ctttatcggg
    31381 gagtcaaaca tcttgccagg taccatgatt gaggactact tggtcgaatt taacggcaaa
    31441 cgctttgaag cggttgatgg tgggatgaag ccaaatgaac ctgttgaggt cgttattcgt
    31501 ccagaggact tgcgcattac ccttcctgaa gaaggcaagc tccaagttaa ggtcgatacc
    31561 cagctcttcc gtggggtgca ttatgaaatt atcgcctatg acgaacttgg aaatgaatgg
    31621 atgatccact caacccgtaa ggccatcgtg ggtgaggaaa tcggtctgga ctttgaacca
    31681 gaagacatcc acatcatgcg tctcaatgaa accgaagaag agttcgatgc tcgtatcgaa
    31741 gaatacgtgg aaatcgaaga gcaagaagca ggtctgatca atgcgatcga ggaggaaaga
    31801 gatgaagaaa acaagctcta aactctttgt agtgccctac atgctttgga ttgccctctt
    31861 tgtattggca cccttggtct tgattttcgg acaatccttt ttcaacattg aaggccagtt
    31921 tagtttagaa aattataaat cttactttgc gtcacaaaac ttgacctacc tcaaaatgag
    31981 tttcaactca gtgctttatg cagggattgt gacctttgta accttgctta tcagctatcc
    32041 aacagccctc tttttgaccc gtctcaagca ccgtcaactc tggctcatgc tgattatcct
    32101 tcctacctgg atcaatttgc tccttaaagc ctatgctttt atcgggattt ttggtcaaaa
    32161 tggctctatt aaccaattct tggaatttat cggaattggt tcacaacagt tgctttttac
    32221 cgatttttcc tttatctttg tcgcaagcta catcgagctc ccctttatga ttttgccgat
    32281 tttcaatgtc ttagacgata tggataataa tctcatcaat gctagttacg accttggtgc
    32341 aactaagtgg gagaccttcc gtcatgtcat cttccctcta tctatgaacg gtgtgcgaag
    32401 tggggttcag tcggtcttta tcccaagttt gagtctcttc atgctgaccc gtttgattgg
    32461 tgggaaccgc gttatcacct tggggacggc tattgagcag aattttctaa ccaatgacaa
    32521 ctatggtatg ggttcaacta tcggtgtgat tctcatcctg accatgttca tcaccatgtg
    32581 ggtgactaag gaaaggagag aacgatgaaa aaatttgcca acctttatct gggactggtc
    32641 tttctggtcc tctacctgcc tatcttttac ttgattggct atgcctttaa tgctggtgat
    32701 gatatgaata gctttacagg ttttagctgg actcactttg aaaccatgtt tggagatggg
    32761 agactcatgc tgattttggc tcagacattt ttcttggcct tcctatcagc cttgatagcg
    32821 accattatcg ggacttttgg tgccatttac atctaccagt ctcgtaagaa ataccaagaa
    32881 gcctttctat cactcaataa tatcctcatg gttgcgcctg acgttatgat tggtgctagc
    32941 ttcttgattc tctttaccca actcaagttt tcacttggct ttttgaccgt tctatctagt
    33001 catgtggcct tctccattcc tatcgtggtc ttgatggtct tgcctcgact caaggaaatg
    33061 aatggcgaca tgattcatgc ggcctatgac ttgggagcta gtcaatttca gatgtttaag
    33121 gaaatcatgc ttccttacct gactccgtct atcattgctg gttatttcat ggccttcacc
    33181 tattcgttag atgactttgc cgtgaccttc tttgtaacag gaaatggctt ttcaacccta
    33241 tcagtcgaga tttactctcg tgctcgcaag gggatttcgc tagaaatcaa tgccctttct
    33301 gctctagtct ttctctttag tattatccta gttgtaggtt attactttat ctctcgtgag
    33361 aaggaggagc aagcatgaaa aaaatctatt catttttagc aggaattgca gcgattatcc
    33421 ttgtcttgtg gggaattgcg actcatttag atagtaaaat caatagtcga gatagtcaaa
    33481 aattggttat ctataactgg ggagactata tcgatcctga actcttgact cagtttacag
    33541 aagaaacagg aattcaagtt cagtacgagg cttttgactc caacgaagcc atgtacacta
    33601 agataaagca gggtggaacg acctacgata ttgccattcc aagtgaatac atgattaaca
    33661 agatgaagga cgaagacctc ttggttccgc ttgattattc aaaaattgaa ggaatcgaaa
    33721 atatcggacc agagtttctc aaccagtcct ttgacccagg taataaattc tccatccctt
    33781 acttctgggg aaccttagga attgtctaca acgaaaccat ggtagatgaa gcgcctgagc
    33841 attgggatga cctttggaag ctggagtata agaattctat catgcttttt gatggggcgc
    33901 gtgaggtgct gggactagga ctcaattccc tcggctacag cctcaactcc aaggatccgc
    33961 agcagttgga agagacagtg gataagctct acaaactgac tccaaatatc aaggctatcg
    34021 ttgcggacga gatgaagggc tacatgattc agaataatgt tgcaatcggc gtgaccttct
    34081 ctggtgaagc cagccaaatg ttagaaaaaa atgaaaatct acgttatgtg gtaccgacag
    34141 aggccagcaa tctttggttt gacaatatgg tcattcccaa aacagttaaa aatcaagact
    34201 cagcctatgc ctttatcaac tttatgttga aacctgaaaa tgctctccaa aatgcggagt
    34261 atgtcggcta ttcaacacca aacctaccag cgaaggaatt gctcccagag gaaacaaagg
    34321 aagataaggc cttctatccc gatgttgaaa ccatgaaaca cctagaagtt tatgagaaat
    34381 ttgaccataa atggacaggg aaatatagcg acctcttcct acagtttaaa atgtatcgga
    34441 agtaggagat aaacgtaaga agacgaatca gtcaagctgg ttcgttttta aggaatagaa
    34501 gtcagttttt agagccctat ctttttctat tctagttgtt tatttgttta tttgcttatt
    34561 tgcttgccta gtagtatact aagcctatac tcttcaaacc acgtcagcgt tgccttgccg
    34621 tactcaagta cagcttgaag ctagcttcct agtttgcttt ttgattttta ttgagtatta
    34681 accttacaga aagcggcaac aaataatgaa aatgtctact tttttcaaaa aaagtttctg
    34741 gccaaccttt atgattgtta accaaactgc tatactattc catttaaatg atggcttgga
    34801 tcgacaatac ctaacaactg agtccatata ttgggtgata ggcaccttta tatttggaaa
    34861 tattctagta gctgtgttta gtaatatgaa aatttgggat aaaaagaaaa atggcagtaa
    34921 gaaaaaatat atcctgaaaa agtaatcaga gatgtaggga attggtctaa ttcaacggag
    34981 atcatttcca gttgacgcaa gcttaaaaaa acgttataat aagaaagttg agaattgatt
    35041 ttcacttgtc ttagtccaga gaaatggcgg tgctgcgagc catctaagct aggaagtcat
    35101 gctactcaat catacaattg cataagaaca agagaatgac aagttcattg aatgaaggtg
    35161 gtaccgcggt ttttcgccct tcgtgatatg agcttgtctt ttgatttttg gaggtgttga
    35221 tgaaaacatt tcttgtcaaa caaaagtttc gtcttggagg cgaacgcttc gctatcaagg
    35281 atgacagggg agaaattgcc tatcaggtgg agggatcatt ttttaagatt cccaaaactt
    35341 ttaccatcta tgatgcggct ggtgaacaag tcagtcagat cagtaaagaa atcttgacct
    35401 tgcttcctcg ttttgagatt cagcttcggg atggctcgag ttttgtcatt cgtaagaagt
    35461 tgaccttctg gcgagataag tatgagtttg ataatctagg tcttcgtatc gagggcaata
    35521 tctgggattt gaatttcaaa ttgctggatg atcgcgatca gttgattgcg gaaattaaga
    35581 aggaactctt ccatctgacc tctacctata ccgtaacggt tcttgaagac gcttatgcag
    35641 acctagtcat ttccctctgt gtcgcgattg actatgtgga aatgctggaa agccaatcac
    35701 attaaacaag tgaataagga gacaatatga aacaactatc tagtgcacaa gtacgccaaa
    35761 tgtggcttga tttctgggcg accaaaggtc actcagtaga accatcagta agtttggttc
    35821 ctgtaaatga cccaactctt ttgtggatca actctggggt agcaaccctt aagaaatact
    35881 ttgacgggac cattatccct gaaaatccac gtattaccaa tgcccaaaag gctatccgta
    35941 ccaacgacat cgaaaacgta gggaagactg cgcgtcacca taccatgttt gaaatgctgg
    36001 ggaacttctc tatcggggat tacttccgtg acgaagctat cacttgggct tatgagcttt
    36061 tgacaagccc tgaatggttt gatttccctg ctgaaaaact ttacatgacc tactatccag
    36121 acgataaaga ttcttacaac cgctggattg aagtgggagt ggatccaagt cacttgattc
    36181 caattgagga caacttctgg gaaatcggtg cgggaccttc tggaccagat acagaaatct
    36241 tctttgaccg tggggaagcc tttgacccag aaaatatcgg tcttcgcctg cttgcagaag
    36301 atattgaaaa cgaccgttat attgaaatct ggaacatcgt tttgtcacaa tttaacgcag
    36361 accctgctgt tcctcgtagc gaatacaagg aattgccaca taagaacatt gatacgggcg
    36421 ctggtttgga gcgtttggtg gccgttatcc aaggggctaa gaccaacttt gaaacggacc
    36481 tcttcatgcc gattatccgt gaagtcgaga aattgtctgg taaggtttat gaccaagatg
    36541 gcgacaacat gagcttcaag gttatcgcag accacattcg ttctctttca tttgctatcg
    36601 gtgatggtgc ccttccagga aatgaaggtc gtggttatgt tcttcgtcgt cttctccgtc
    36661 gtgcttctat gcatggtcaa aaattgggta tcaacgagcc tttcctttac aaattggttc
    36721 caactgttgg aaaaatcatg gaaagctact acccagaagt gcttgagaaa cgtgacttta
    36781 ttgagaaaat cgttaagagc gaagaagaat catttgcccg tacccttcac tcaggtcaac
    36841 actttgccca aggcattgtg gcagacttga aagaaaaagg tcaatctgtc attgctggtc
    36901 aagatgtctt taaactctat gatacttatg ggttcccagt tgaattgact gaagaaatcg
    36961 ctgaagaagc tggtatgact gtagaccgtg aaggttttga agcagccatg aaagaacagc
    37021 aagaacgcgc gcgtgcgtca gctgtcaagg gtggctcaat gggtatgcaa aatgaaactc
    37081 ttcaaaacat cactgtagaa agtgtcttca actacaatac tagccaattg tcttctaaat
    37141 tggtagctat cgttgctgac aatgcagaag taggagctgt ttcagaagga actgcctctc
    37201 ttatctttgc ggaaacgtca ttttatgctg aaatgggtgg acaggtagct gactacggac
    37261 aaatcttgga tgagtcaggt aagattgtgg ctactgtgac caatgttcag aaagccccaa
    37321 atggtcaagc ccttcataca gttgaagtcc ttgcaccgct tgccttgaac caagaatata
    37381 ccttggcaat tgatagcaat cgccgtcacc gtgtcatgaa aaaccacact gcgactcatt
    37441 tgcttcacgc tgcccttcac aatatccttg gaaaccacgc aacacaggca ggatctctta
    37501 acgaagttga attccttcgc tttgacttta cccacttcca agcagtaact gctgaggaac
    37561 ttcgtgcgat tgaacagcaa gttaacgaga aaatttggga agcacttgaa gtgaagacag
    37621 ttgaaacgga tattgacact gctaaagaaa tgggagctat ggccctcttt ggtgagaaat
    37681 acggcaagga agttcgtgtc gtgactatcg gtgactactc tattgaactt tgtggtggta
    37741 ctcatgttga caacacttct gagattggtc tcttcaaaat tgtcaaagaa gaaggaatcg
    37801 gttcaggaac tcgccgtatc ttggcagtga ctggtaagga agcctttgaa gcctatcgtg
    37861 aacaagagga tgctcttaaa gctatcgcag caaccttgaa agcacctcaa gtcaaggaag
    37921 tacctcacaa ggtagaagga cttcaagaac aacttcgtca acttcaaaaa gaaaatgctg
    37981 agttgaaaga aaaagccgca gctgcagccg caggcgatat cttcaaagat gttaaggaag
    38041 tcaacggtca tcgttacatt gctagtcaag tgtctgtatc cgatgccggt gcccttcgta
    38101 cttttgcaga taactggaaa caaaaagact actctgatct tcttgtccta gttgccgcta
    38161 tcggtgacaa agtcaatgtc cttgtagcaa gcaagacaaa agaccttcat gcaggaaacc
    38221 ttgtcaaaga attagcacca atcatcgatg gacgtggtgg tggtaaacca gacatggcca
    38281 tggcaggagg aagcaaccaa gctaagatcc aagaattgtt ggatgcagta gcaggtaaat
    38341 tgtaatcaag taaagatcta tccatttggg taggtctttt tgtgaataca aaaaagccaa
    38401 atccgcttgg acctagcttg gttattatga gctattagat ggtattgact gcccagacac
    38461 ttacggatct agctgagaca gggaattgtc cataaccttc ctcatcaatt gtaacttgac
    38521 cttggtggtt accaagtaaa tctacaaagg tttgattagt ccattcttga ccgacaaaca
    38581 ttgacttgct gttttcttgg tcatttgaga taaggactgc gattggggat tgattttcag
    38641 cacctgaacg tacccaaccg atacagttag catggtcaaa gtagtcattt tgttctccat
    38701 aggccaagtc ttttcggatg gctaggaggc ggtcaaggat ttctttgaaa tcttcttgag
    38761 catactggcc tgaaatccca tagtagtctc cgtaaaagac acatggaagg ccgtcttggc
    38821 gtaacaaaat gagggcatag gctgctggct tgaaccattc ttcaacggta gactcaaggg
    38881 cttgtcctcg ttgggtatcg tggttgtcga caaaagtcac agccttgtca ggcttgagtt
    38941 caaccaggct atctgtgaaa atgccacgaa ggtcatagtt tgcgccagct tgactggctt
    39001 caaagagatt ctggtggaga cgaacatcga caaggtcaaa gtgttcttcc gttttttcga
    39061 gatagtccag attggcttcc ttgtctgggt tccaaaattc accaaaaaca tagaaatcgt
    39121 caccgtattt ttccttcata tcgcggatga agttgcgcat aaagaaagag tcaatatgct
    39181 taacggcatc caaacggaaa ccagctacac cagtcgtttc catgaaccaa tcagcccagt
    39241 catagatgtt ttggatgact tcaggatgtt taaagtctag gtcggcatac atgaggtagt
    39301 cgtagtttcc gttttcgtta tcgaccaatt ccttgttagc ccagcccttg ttgtcccctt
    39361 ggatcagata aatcccagat ttactgcgtt tggcatcgta gtctgtaccg gtgaagtggt
    39421 accaatgcca gtggaagcca ttataggtat cttggcgacc atcgaaggta aaactagtcc
    39481 agccattgat ggtgaagggt tctccaagtt caactgtacg gtctacagga tcaacttcga
    39541 taacctgaaa ggcttccctg ttatcggcag cagccttgtg gttgagaact acatcggcca
    39601 taggttgaat tccctgttct ttaagggctt gaatggcttg aagatagtct tctttgaaac
    39661 catacttggt gcggacagtc cctttttggt tgaactctcc taagtcaaat aagtcataga
    39721 ccccatagcc gacatctttt tcgttggttg ccttgaaggc tggtggcatc cagacgtgac
    39781 tgatccccag atgagctagg tgtggagcat tttcagccag acgcgtccag tgttgaccgt
    39841 cgtggggcag ataccattca aagtattgca tgagtgtttg attttgcatg atgtttcctc
    39901 ttacttgtca atcttgttct ttattctatc ataaagtatc tctcggcgca aacgtttgcg
    39961 taagatagaa ggaaactatt ttaactactt aaaataaagt attgattttt ttgtatcaaa
    40021 gtgctagtat agcgatgtat aatacagata aagataggag ttgtcccatg attgaatttc
    40081 aaaatgttag taagttgtat ggtgataaag aggccttgag taatctcaat ttgcagattg
    40141 aaaatggaga gattatgggc ttgattggtc ataatggggc tggaaaatcg accaccataa
    40201 aatccctagt cagtatcatt tcacccagca gtggtcgtat tttggtagac ggtcaggagt
    40261 tatcggaaaa tcgcttggcg atcaaacgaa agattggcta cgtagcagac tcgcctgact
    40321 tatttttacg cttaacggcc aatgaatttt gggaattgat cgcttcatcc tatgatctga
    40381 ctagctctga cttggagact agtctagcta ggctattgaa cgtttttgat tttgctgaaa
    40441 accgctatca ggttattgaa actctttctc acggaatgcg tcagaaagtc tttgtcattg
    40501 gggcactctt gtctgctcct gatatttggg ttttggacga acccttgact ggtttggatc
    40561 cccaggccgc ctttgatttg aagcaaatga tgaaggaaca tgcacaaaaa ggcaagacgg
    40621 tcttgttttc aactcatgtc cttgaggtag ccgagcaagt ctgtgatcgg attgctattt
    40681 tgaaaaaggg gcatttgatc tattgtggta gtgtagagaa cttgaggaaa gaccacccag
    40741 accagttttt ggaaagtatc taccttagtc ttgctggtag aaaagaggag gttgcggatg
    40801 cgtctcaagg tcattaaaaa attagttgat atcaatatcc tctattcatc tcaagaagct
    40861 aatctggcta atctacgaaa gaagcaggct aagaatcctg ggaaaaaagt aaatgtttct
    40921 gctagagtcc taagttctta cattttttcc agtctcttga tgctcatctg ttttagtaat
    40981 atagccattc attttccttt tgaggaaatg cctatttatt ttagctcgat ggttgctatt
    41041 ttactggtgc tggccttttc aacttctttc actgcctttt acaatgtctt ttatgagagt
    41101 aaggacctgg cctcctatag gccctatgcc tttaaagaat cagagattat aatggccaaa
    41161 ggtctgtctg tcctcttgcc agctctaact ggaattgtac caatcctagc ttattttcta
    41221 gccctctata ttagtctagc tccttctctt tggctgggtt tgcctttgat gctactgtcc
    41281 ttgaccttat tatttgtctc tgttacttta gtgacggtag tggcagtaca tttcttggct
    41341 cagactaggg tcttcagaaa gtatcagtct attttttcga atgtgatgat tgggatagga
    41401 gttctcatac ctttaatatt tatcttcttt cttcagtcga cttttggaag tattgttgac
    41461 aaagttagag acattccatt tctcctttat cctcttcata tcttttacaa aatagcagtg
    41521 gagccttttt cgacagaagc cttagtgggt ctgctcgctt ggataggact aactctcttc
    41581 ctgctttatc tgaccaaaaa gaaggtcctt cctcgttttt atgacgtgat actgcttaac
    41641 agtgaggaga aggtcaaaaa agaacgtcgc agcaaggaga ggatttcaac tactaaaaag
    41701 ggctttttcc gtatggtttt acgctaccac ctcaccctct tgggacaggg gactggtgtg
    41761 attacagtgc tttttacaag tgctttcctt ccttatctca tgatgatcag tctgatttcc
    41821 aaaatccgag attctcagat agttccagac attcatcctc catactggtt acccttgttt
    41881 tttgtaggag tgtttatagc agttgtcaat aacaatatca ccagcctgca ttcaattgcc
    41941 ttgtccttgg agagggaaaa tgttgatttt ctgaagagtt taccctttga ctttgctcgt
    42001 tatgtgaaag tgaaattttg gattatcttt gctgttcagt cctttttacc agttctgact
    42061 ttgctcggtc tttctctata tctaggcttg cccatccttt cgatgattta ccttcttgta
    42121 gtctggatca ttgccagtgt catcctttct tgccaccatt actttaagga cgttaaaaat
    42181 ctgtcaacca attggagtag cattacggac ctggtgaatc gttcaaatgg catagtcgcc
    42241 atagttttat tgtttattta tagtgcaatc ctgatggccc ttgtaattgg gagcatattc
    42301 ttggttcagt ctctctcccc tatccttgcc atcaacttgg gagtaggagc tcttatcgtc
    42361 ttgcttgctc ttgctatttt tggctatcat tattacctgt cacgcatatt ggcagaaata
    42421 gaaaaaagat gagatagttg gttgcttgct tgataaattc aattcgacaa acgcttttat
    42481 agtttgttag aatgtagttg taaatgatta agattggtaa tcaaaaatat agggaggaat
    42541 gttttgaata agaaatataa tatagttcta ttattgttgt ttatagttta tttattggga
    42601 tatttttcaa tttcaaaaac gttaattcct ataatgtgtg tgatccaagt atttttgata
    42661 gaacatatat ttagagttcg aaatagaatg atgcaaatag gtgaaatttt aattattgtt
    42721 gcttctataa tattatttat tgatagtata ttgagtttgt aacaaaaggc ttttctataa
    42781 aatcaaattt tccagatacc tattgaagca gatttatttc ttcatctttc ttctactacc
    42841 tttgtcacta aatttgacag acacatattg ctgattcaac ctctctacct ataatctcac
    42901 agttaacctg aggctagttt catagtttgc tatttgattt tcgttgataa aaagaaatgc
    42961 tcctccaaga tggaagagca ttttttattg tgattcttac acatttactt cctagttttg
    43021 caggaagtct agtataccat tttttaaaag aagagtaaaa aagcaagggt agtttctttt
    43081 ttgagaattg tctaaaagtt tgatataatg gtagttatga atagaataag agtcagcaaa
    43141 agggttgaaa agaagcttgc taaggggcta gttttactag aagccagtga tcttgagaat
    43201 gtcaatctta aggatcagga agtagaggtg cagggtcagg aaggaaactt tcttgggact
    43261 gcctaccttt ctcagcaaaa caagggcttg ggctggtttg tcagcaaaga caaggtggcc
    43321 ttcaatcaag ctttctttga aacgttgttt agaaaagcca aagaaaagag aaacgcctac
    43381 tatcaagatg atttgacaac tgcctttcgt ctctttaatc aagagggaga tggctttggg
    43441 ggtctgacag tggaccttta tggcgactac gccgtctttt cttggtataa ctcttatgtt
    43501 tatcagattc gtcagactat atcagaagcc tttagacagg ttttccctga ggttttagga
    43561 gcttatgaga aaatccgctt taagggtttg gactatgaat ctgcccatgt ttatggtcaa
    43621 gaagcacctg actttttcac tgttttagaa aatggtgtcc tgtatcaagt ctttatgaat
    43681 gatggcttga tgacaggaat tttcctagac cagcatgagg ttcgcggtag tttagttgac
    43741 ggcttggcta tgggtaaatc cttactcaat atgttttcct acacagcggc tttttcagta
    43801 gctgcggcca tgggaggagc tagccagaca acttctgttg atctagccaa acgttcacga
    43861 gaattgtctc aagcgcattt tcaggcaaat gggctcagca cagacgagca tcgttttata
    43921 gtcatggatg tctttgagta tttcaaatat gccaaacgca aagacttgac ctacgatgtg
    43981 attgtcctag atccgcctag ctttgctcgg aataaaaaac aaactttctc tgtggccaag
    44041 gattatcaca agttgatttc ccagagtctt gagattttaa atccgggagg gattatcatt
    44101 gccagtacca atgctgccaa tgtttcccgt cagaaattta cagaacaaat tgataaaggt
    44161 tttgcaggaa gaagttacca gattttaaac aaatatggtc ttccagcaga ttttgcctat
    44221 aataaaaaag atgaaagtag taattacctc aaggtgatta gtatgaaggt tagtaaatga
    44281 aattaatcgt ttcagtaatg ccaagaagtt tagaggaggc tcaggctctg gatgccacga
    44341 ggtacttgga tgccgacatc attgaatggc gtgccgacta tctgcctaaa gaagcgattt
    44401 tgcaggtagc tccagccatt tttgaaaaat tcgcaggccg tgagttggtt ttcacgctac
    44461 gaactcgctc cgaaggtgga gaaatcgacc tttctccaga agagtatatc catctaatca
    44521 aggaagttgc gcaactctat caaccagact atattgattt tgagtactat agctacaagg
    44581 atgtttttga ggaaatgctg gacttcccaa atcttgtttt gagttaccat aatttccaag
    44641 aaacacctga gaacatgatg gaaatcttgt cagagttgac gatcctaaat ccaaaacttg
    44701 ttaaggttgc ggtgatggct cacacggagc aggatgtctt agacttgatg aactatacac
    44761 gaggctttaa aaccctcaat cctgaacagg aatatgtgac catttctatg ggtaaggtgg
    44821 gcaaggtctc tcgtatcact gcggatgtga ctggttcgag ttggtctttt gccagtctgg
    44881 atgaggttag tgcccctggg cagatttctc tagctagcat gaaaaaaatc agggagattt
    44941 tggatgaagc ttgatggcta tacacgttta gctgcagttg ttgccaatcc tattaagcat
    45001 tctatttctc ccttcatcca caatagagcc tttgaggcga cagctaccaa cggtgcttat
    45061 gtggcttggg agattgaagc gagtgacttg gcagaaacag tggccaatat tcgtcgctac
    45121 cagatgtttg gcatcaatct gtccatgccc tataaggagc aggtgattcc ttatttggat
    45181 gagctaagcg atgaagcgcg cttgattggt gcggttaata cggttgtcaa tgagaatggc
    45241 aatttaattg gatataatac agatggcaag ggatttttta agtgcttgcc ttcttttaca
    45301 atttcaggta aaaagatgac cctgctgggt gcaggtggtg cggctaaatc aatcttggca
    45361 caggctattt tggatggcgt cagtcagatt tcggtctttg ttcgttccgt ttctatggaa
    45421 aaaacaagac cttacctaga caagttacag gagcagacag gctttaaagt ggatttgtgt
    45481 gctttagaat atgtttctga actgcaagca aggattgccg agtcggattt gctagttaat
    45541 gccaccagtg tgggcatgga tggccaatcc tctcctgttc ctgaaaacat agtcttacca
    45601 gaaactcttt tagttgcaga tatcatatac caaccctttg aaacaccgtt tttgaaatgg
    45661 gctagaagtc agggcaatcc agcagtcaat ggtctgggaa tgttgctcta tcaagctgca
    45721 gaagcttttc aactgtggac aggcaaggaa atgccgacag aagagatttg gcagtcttta
    45781 acagaaaaat accaataaag aaagggagac tctcctatga aaatcagaat cgatattcct
    45841 catcatcctt atgatattca gattgaaaaa ggttgtatgg cccaggctgg tcagtggttg
    45901 cgagaactct ggcaaccgca aaaggtagtc attgtgacag ataaccatgt agcctctctc
    45961 tatgcagaga aggtcaagct cagcctagaa gatgctggtt ttcaggtagc tgtttttgat
    46021 ttcttagaag gtgaagaaag aaagaattta actactgttc agaaagtcta tgaatttcta
    46081 gtcaagcaag gtctgactcg tagcgatgga atcgttgctc ttggtggtgg cgttgttggg
    46141 gacctggctg gctttgtagc ctctacctat atgcggggta ttcactttgt tcagattccg
    46201 actagtttga cagctcaggt tgattcttct atcggtggaa agacaggcgt taacacacca
    46261 tttgctaaaa atatggtggg gacctttgcc caaccagatg gggttctgat tgatccactt
    46321 gttcttgaaa ccctcggaaa aagagagttg attgaaggga tgggtgaagt tatcaagtat
    46381 ggcttgattg aggatccaga actgtgggct ctcttgacgg gactgaatgg ttctgttgag
    46441 agtattttgg aacatgcaga gaccttgatt gaacattctt gtcaggtgaa gcgcaagatg
    46501 gtggttgaag atgagttgga caatggtatt cgtctttacc tcaattttgg ccacactatt
    46561 ggccatgcca tcgaagcgac tgccggttat ggcaaggtca tgcatggaga ggctgttgcc
    46621 atgggaatgg tacagatttc caagattgct gaggaaaaag gcctcatgcc agctggcatt
    46681 acccaatcta tcacagagat gtgtcagaaa ttcggcttgc ctgttgacta tgaaaattgg
    46741 gaagttgaca agctttatca ggctcttact catgacaaga aagcgcgtgg caacaccttg
    46801 aaattggtct tggtgccaga gcttggttca gcgatcattc acccagtttc tctggaagag
    46861 atgaaagact acttggtaaa ataaggagag tgtatgagat atttaactgc aggagaatca
    46921 cacggccccc gtctaacagc tattattgat ggaattccag ctggacttcc attgacagct
    46981 gaggatatca atgaggacct tagacgccgt cagggtggct acggtcgtgg tggtcgtatg
    47041 aagattgaga atgaccaggt tgtctttact tcgggcgttc gccacgggaa gacgacaggg
    47101 gcgcctatta ctatggatgt catcaataag gaccaccaga aatggctgga catcatgtct
    47161 gcggaggaca ttgaagaccg tcttaaaagc aagcggaaaa ttactcatcc tcgcccaggt
    47221 catgccgatt tggttggggg gattaagtac cgttttgatg atttgcgaaa ttctttggag
    47281 cgttcatcag ctcgtgaaac caccatgcgg gtggcagttg gtgcagtagc caaacgcctc
    47341 ttggctgagt tggatatgga gattgccaac catgtcgtgg tctttggtgg caaggaaatc
    47401 gatgttcctg aaaatctgac agtcgctgaa attaagcaaa gagctgccca gtctgaagtt
    47461 tctattgtca accaagaacg agaacaggaa atcaaggact atattgacca aatcaaacgt
    47521 gatggtgata ccatcggtgg ggttgtggag acagtcgtcg gaggcgttcc agttggtctt
    47581 ggttcctatg tccaatggga tagaaaattg gatgcaagat tggctcaagc tgttgtctct
    47641 atcaatgcct ttaaaggggt ggaatttggt cttggctttg aggctggtta tcgtaaaggc
    47701 agccaagtta tggatgaaat tctctggtct aaagaagacg gttatactcg ccgtaccaat
    47761 aatctaggtg gttttgaagg tggtatgact aatgggcaac ccatcgttgt tcgtggggtc
    47821 atgaaaccca ttcctactct ttataaacct cttatgagtg tggatatcga aacccacgaa
    47881 ccttacaagg caaccgtgga gagaagtgat ccgactgctc ttccagctgc aggaatggtc
    47941 atggaagcag ttgtagcaac ggttctggcg caagaaatcc tcgaaaaatt ctcatcagat
    48001 aatcttgagg aactaaaaga agcggtagcc aaacaccgag actatacaaa gaactattaa
    48061 ggagttccta tggcaaaaac aatctatatc gcaggtcttg ggttgattgg agcctctatg
    48121 gcacttggta tcaaacgcga tcatccagat tatgaaattt taggttataa tcgtagtcaa
    48181 gcttcgagag atatcgcctt gaaagaaggc atgattgacc gtgcaacgga tgattttgct
    48241 agttttgctc ctttggcaga tgtcattatc ctcagcttgc caatcaaaca aactattgct
    48301 ttcattaagg agttggccaa tttggatttg cgagaaggcg ttattatttc agatgctggt
    48361 tcgaccaagt caaccattgt ggatgcggcg gagcagtatt tggctggcaa gtctgttcgc
    48421 tttgtcgggg cccatcccat ggctggtagt cacaagacag gggctgcttc ggcagatgtc
    48481 aatctttttg aaaatgccta ttatatcttt acaccttcaa gcctgacaag tcaggacacg
    48541 cttaaggaaa tgaaggatct gctttcaggt cttcatgctc gttttatcga gattgatgcc
    48601 aaggagcatg atcgtgtcac ttctcagatt agccattttc ctcatatttt ggcttctagt
    48661 ctcatggagc agactgcggt ctatgctcaa gagcatgaga tggcaaggcg ctttgcggca
    48721 ggtggttttc gagatatgac ccgaattgcg gaaagcgagc caggaatgtg gacctccatt
    48781 ctcttgtcca atagcgagat cattctggat agaattgagg atttcaagga acgtttggaa
    48841 gcgattggtc aggccattag taagggagat gaagagcaaa tttggaactt ttttaaccaa
    48901 gcgcgtgaac aacgccagac catggaaatc cataagcgtg gtggtgtgga tagctcttac
    48961 gacctctatg ttgacgttcc tgatgaagaa gatgtcatcc tgcggatttt ggaactgcta
    49021 cgtggaactt ccttggttaa tatccacatc aacgaggaaa atcgtgagga tattcacgga
    49081 atcctacaaa tttcatttaa aaatgctcaa gacttggaaa gagctgagca tctcataaca
    49141 gaaaatactg actatacagt cgtcatcaaa taaggagaag aacatgtcaa atatttacga
    49201 tagtgcaaac gaactcagtc gcggtctacg cggattacca gaatacaagg ctgttaaagc
    49261 agctaaagat gcgattgcag cagatgctga ggcaagcaaa atctttacag attatcttgc
    49321 ctttcaagag gaaattcaaa aactagcaca gacaggtcaa atgccagatg cgtccttcca
    49381 agctaagatg gaaggctttg gtaaacagat tcaaggaaat agcctcttgt cagaattctt
    49441 taccaagcaa caacaattgg ccatttacct ttctgacatt gaaaaaattg tttttgaacc
    49501 agtttcagaa ttgctgaaat aagaaaagaa ctatcctaaa gtcaggaatt tttaaggaat
    49561 ttctggcttt ttatgataaa ataggtaaaa gtattgcaag tatgaggtcc agtatgaaac
    49621 taaaaacaaa cattcgccat ttacatggta gtatccgcgt cccaggtgac aagtctatca
    49681 gccaccgttc cattatcttt ggaagtttgg ctgagggtga gaccaaggtt tatgatattc
    49741 tgcgaggcga agacgttctt tcgaccatgc aggtttttcg tgaccttggt gttgaaattg
    49801 aggataaaga tggggttatt accattcaag gtgtaggcat ggctggctta aaagcgccgc
    49861 aaaatgccct taatatggga aattctggca cctcgattcg cctgatttca ggtgtccttg
    49921 ctggtgcaga tttcgaagta gagatgtttg gagatgatag tctttccaaa cgtcctatgg
    49981 accgtgtgac ccttccactg aaaaaaatgg gcgtcagcat ttcagggcaa actgaacgag
    50041 acttgcctcc ccttcgctta aaagggacga aaaacctaag ccctattcat tatgagttgc
    50101 caattgcctc tgcccaagtc aagtcagcct tgatgtttgc agccttacaa gctaaggggg
    50161 agtcagttat tatcgaaaaa gaatacaccc gtaatcatac tgaagatatg ttgcaacaat
    50221 ttggtggtca tttaagtgtg gatggtaaga aaatcacagt ccaagggcca caaaaattga
    50281 caggacagaa ggtggtcgta ccaggagata tttccagtgc agccttttgg ttagtcgcag
    50341 gtttgattgc tccaaattct cgtctagtgc tgcagaatgt ggggatcaac gaaactcgca
    50401 ccggtattat tgatgtcatt cgtgccatgg gtggaaaatt ggaaataact gaaatcgatc
    50461 cagtcgctaa atctgcaacc ttgattgttg agtcttctga cttgaaagga acagagattt
    50521 gtggcgcttt gattccacgt ttgattgatg aattgcctat tattgcccta cttgcgaccc
    50581 aagcccaagg tgtaacagtt attaaagatg ctgaggagct caaggtcaag gaaacagacc
    50641 gtattcaggt tgtggcagac gccttaaata gtatgggagc agatattact cctacggcag
    50701 atgggatgat tatcaaagga aaatcagctc ttcacggtgc tagagtcaat acgtttggtg
    50761 accaccgtat cggcatgatg acagctatcg cagccctatt ggttgcagat ggagaggtgg
    50821 agcttgaccg tgcagaagcc atcaatacca gctatcctag tttctttgat gatttggaga
    50881 gcttgattca tggctaaggt gttattaggg tttatggggg ctggaaaatc aactattgca
    50941 agaggcttgg accctaatta ccttgatatg gatgctctga ttgagaagcg cctaggtatg
    51001 tccattgcga attttttcgc tgaaaaggga gaatcagcct ttcgtcaggt agaatcagaa
    51061 gtcctagctg atttactaca aacagaccaa gtcgtgtcaa ctggaggagg agtggttatt
    51121 tctcagagaa atcgtgactt actcaagact aatacagata acatctacct gaaagcagat
    51181 tttgaaaccc tctacctacg tatcgtagct gataaggaca atcagcgacc gctttttcta
    51241 aataatagca aggaagaact agtagctatt tttcaagaaa gacaggcttg gtatgaggaa
    51301 gtggctagtc gggttttgga tgtgaccaag ctaagcccag aggaaattat agaggaacta
    51361 agatgaaaat tgcttatcta ggtcccaaag gatcattttc acaccacgtt gtgcagacag
    51421 cttttcctca tgaggaattg caggcttttg ccaacattac agatgttatc aaggcttatg
    51481 agcaaggatt agtggactat tctgtggtgc cagttgaaaa ttctattgag ggtagtgttc
    51541 atgaaacctt ggactatctt tttcatcagg ctcacatcca agcagtagca gaaatcgttc
    51601 agcctattca tcagcagttg atggtggttc caggccatac taagattgaa aagatttttt
    51661 cacatccaca ggccttggct caaggaaaga aattcatcga tgaacaatat ccagaggctc
    51721 aaatcgaggt aacagctagt acagcttatg cggcccgttt tatttccgaa catccagacc
    51781 agccctttgc agcagttgca cctagaagtt ctgctgaaga atatggattg gaactgattg
    51841 ccgaggatat tcaggaaatg gaagccaatt tcacacgttt ctgggttcta ggagctgaaa
    51901 agcctagtat tcccttgcaa gcacaaactg aaaagatgag tttggccttg acattacctg
    51961 acaaccttcc aggtgcactt tataaggccc tgtcgacctt tgcttggcga ggaattgact
    52021 tgacaaaaat tgaaagtcgt ccactcaaga cagcactggg tgaatacttt ttcattatcg
    52081 atgtggatta taccgataag gacttggtcc actttgccca aaaagaatta gaagcgattg
    52141 gaatccagta taaaattctg ggtgcctatc ctatttatcc aatatcagac catggaaagg
    52201 agagaagatg agtaaagaaa atcccttaag tcatcatgag cagttgcgtt atgattattt
    52261 gctaaaaaat attcactacc tcaatgagag agaaaaaaat gagtttgcct atttgcaaga
    52321 aaagctaact cttgctagga gaaatagtag ctctagcttg gaacaagaaa gagaagagca
    52381 ggttgactta ccaagttatg cgaaccggag tcgctcacaa tccaaatcac aagcactctc
    52441 ttcccctcca aaaaagaaaa gacggaagct ccgtcttaaa cgaattttta tggtgatttt
    52501 ttcacttttg gtctgtgtgg ctttggccat ggtattcatg tttttgcgtg gttaccaaga
    52561 tgctagcgca aagaaaactg ctgatgcccg ggcagctcaa gtagaagtct ttaatggtca
    52621 ggacactaga gatggagtta atattttaat catgggtact gatggtcgaa tcggccagaa
    52681 cagtgttgag acacgaactg actctattat ggtattaaat gtcgggggct cagataagaa
    52741 aatgaagcta gtcagtttca tgcgtgataa tttggtctat atagatggtt atagtcaagt
    52801 gattaacggt agaaaacaga cagataacaa gttaaacgta gcctacgagt taggagaaca
    52861 agaggggcaa aaaggggcag aaatggttcg ccaagtcttg aaagataatt ttgacttgga
    52921 cattaagtac tacgccttgg ttgatttcca ggcctttgcc acagcgattg acacactttt
    52981 ccctgatggg gtgacgattg atgctcaatt ttcaacattg aatgggcgtc ccctaacaga
    53041 agctacagtc ggagatgatt tatacgctac cgagactgag tctccaaccc aaaccattaa
    53101 agtcggaaaa cagcagatga atggctcgac cctgctcaat tatgctcgtt tccgtgatga
    53161 tgatgaggcg gattacggcc gtacaaaaag acagcaacaa gttttaacag caattttaga
    53221 gcaaattaaa gatcccacta aacttttcac tggttctgaa gctcttggaa aggtttttgc
    53281 tatgacctca accaacgtac cctatacttt cctcctaaca aacggtttat ctgttttgga
    53341 tggagcaaaa aatggtattg aaaaattgac gattccagaa ctgggtgact gggtagatgc
    53401 ctatgatgtt tatggaggct tgggcttgct ggttgatcaa aacaaatatc aaaccaagct
    53461 cgctcaaatg ggcttgagat aagataatac tcaatgaaaa tcaaagtgca aactaggaag
    53521 ctagccgcag gctgctaaaa acacagtttt gaggttatag ataagactga cgaagtcagt
    53581 tacctatacc tacggcaagg tgaagctgac gtgctttgaa gagattttcg aagagtataa
    53641 gacagaaaaa tcaaagtttg atagctattt ggatagcagt caggctttga ttttttacag
    53701 tctgcaatag attttcaccc cttgtttgtg gtataatgaa acgatacgat agaaagaata
    53761 atgaacaata tgactgattt aaaagcaatt caggctcgta gtctggagat ggctgaatat
    53821 tttgtggcct tttgtaaaga acatgatttg ctctgttatc tctgtggcgg aggcgctatt
    53881 ggtacccttc gaaacaaggg atttattcct tgggacgacg acctagactt ttttatgcct
    53941 cgtaaagatt atgagaaatt agcagaatta tggcctcgtt atgcagatga acgttatttc
    54001 ttgtcaaaga gttacaagga ttttgttgat cgtaatcttt ttattaccat tcgtgacaag
    54061 gaaaccacct gtatcaagcc ttatcagcag gatttggatt tgccacatgg tctggccttg
    54121 gatgttttgc ctttggatta ttatccgaaa gatccagctg agcggaaaaa acaggttcgt
    54181 tgggccttga tttattcact cttttgtgcg caaactattc cagaaaagca tggtgctctc
    54241 atgaaatggg gaagtcgcat tttactgggt ttgactccaa aatctctccg ttatcgcatc
    54301 tggaaaaaag ctgagaaaga aatgactaag tatgatttgg ctgattgtga tggcattaca
    54361 gaattatgct caggtcctgg ctacatgaga aacaagtacc caatcacatc ttttgaagac
    54421 aatcttttct tgccatttga gggaacagag atgcctattc caatcggcta tgatgtctat
    54481 ctcagaactg cttttgggga ttatatgacg cctccaccag cagacaagca ggtaccgcat
    54541 catgatgctg tcatcgctga tatggataag tcttatacag aatacaaggg agaatatggt
    54601 ggctaagaaa aaaatcttat tttttatgtg gtctttttct cttggaggtg gtgcagagaa
    54661 gattctatca accattgttt caaatctgga tccagaaaag tatgatattg atattcttga
    54721 aatggagcac tttgacaagg gatatgaatc tgttccaaag catgtacgca ttttaaaatc
    54781 ccttcaagat tatcgccaaa ccagatggtt acgagctttt ttgtggagaa tgagaattta
    54841 ttttccaaga ctggctcgtc gtttgcttgt aaaagatgat tatgatgttg aagtttcttt
    54901 taccattatg aatccaccac tgttgttctc taaaagaaga gaagtcaaga agatatcttg
    54961 gattcatgga agtattgaag aacttcttaa ggatagctct aaaagagaat cacatagaag
    55021 ccagttggat gctgcgaata caattgtagg gatttcaaaa aagaccagca attctatcaa
    55081 ggaagtttat ccagattatg cttctaaatt acagacaatc tacaatggat atgattttca
    55141 gactattcta gaaaaatctc aagagaagat cgatatcgag attgctcctc aaagtatctg
    55201 tactatcgga cggattgagg aaaataaggg ttctgaccgt gtagtggaag tgatacgatt
    55261 attacaccaa gagggaaaaa actatcatct ctattttatc ggggctggtg atatggaaga
    55321 ggaactgaaa aaacgagtca aagagtatgg gattgaggac tatgtacatt tccttggtta
    55381 tcaaaaaaat ccttatcagt atttatctca gacgaaagtt ctcttgtcta tgtctaaaca
    55441 agaaggtttt cctggagtgt atgtggaggc cttgagtctg ggactccctt ttatctctac
    55501 ggacgttgga ggggctgagg aattatccca agaaggacga tttggacaaa tcattgagag
    55561 caatcaagag gcagctcagg cgattactaa ttacatgact tctgcctcaa actttgatgt
    55621 cgatgaggct agccaattca ttcaacaatt tacaattaca aaacaaatcg aacaagtaga
    55681 aaaactatta gaggagtagc atggaaactg cattaattag tgtgattgtg ccagtctata
    55741 atgtggcgca gtacctagaa aaatcgatag cttccattca gaagcagatc tatcaaaatc
    55801 tggaaattat tcttgttgat gatggtgcaa cagatgaaag tggtcgcttg tgtgactcaa
    55861 tcgctgaaca agatgacagg gtgtcagtgc ttcataaaaa gaacgaagga ttgtcgcaag
    55921 cacgaaatga tgggatgaag caggctcacg gggattatct gatttttatt gactcagatg
    55981 attatatcca tccagaaatg attcagagct tatatgagca attagttcaa gaagatgcgg
    56041 atgtttcaag ctgtggtgtc atgaatgtct atgctaatga tgaaagccca cagtcagcca
    56101 atcaggatga ctattttgtc tgtgattctc aaacatttct aaaggaatac ctcataggtg
    56161 aaaaaatacc tgggacgatt tgcaataagc taatcaagag acagattgca actgccctat
    56221 cctttcctaa ggggttgatt tacgaagatg cctattacca ttttgattta atcaagttgg
    56281 ccaagaagta tgtggttaat actaaaccct attattacta tttccataga ggggatagta
    56341 ttacgaccaa accctatgca gagaaggatt tagcctatat tgatatctac caaaagtttt
    56401 ataatgaagt tgtgaaaaac tatcctgact tgaaagaggt cgcttttttc agattggcct
    56461 atgcccactt ctttattctg gataagatgt tgctagatga tcagtataaa cagtttgaag
    56521 cctattctca gattcatcgt tttttaaaag gccatgcctt tgctatttct aggaatccaa
    56581 ttttccgtaa ggggagaaga attagtgctt tggccctatt cataaatatt tccttatatc
    56641 gattcttatt actgaaaaat attgaaaaat ctaaaaaatt acattagaac gggggtgacc
    56701 aagtgattga tgggaaacga ttattattta gtttgaccat agtcagttat gccttgacgc
    56761 tagtaagtgg aattgtgtat ctgtttaata ataataatgt tagcttactt tctactttat
    56821 tgttcttgtt ggttagtagc ttaattgctt gttggaatga tatcaagtat tacttaatcc
    56881 attttatttt ctatttaacc atttttgtat ttctggtatc aagaccgacc attgattatt
    56941 ttagggatgg tgctttggat acctatcatc caatagccta tcgttttgcc tttatagttg
    57001 tcatggtttc gattctgggc ttgaccacag gaggcattct ggctcgttac ttcatagcta
    57061 ggaagaaaat aaaagtagca aatataggaa attctctaaa agaggtttat atcaagcggt
    57121 tacgctttgt atcactagga gtttttcttc taacctatcc tttctatttc attcggttat
    57181 ttgaacggct cttgtatcgt ttgcagactt cctactatgc ctactatgca aattttgaaa
    57241 gtaaactgcc ttattttacc tacattttgt ctacctttac ggtctatgca atgtgtatgt
    57301 atctggcaac caagccaaag aaattgcagg ccacagcagt gcttgtctcc tttattgcag
    57361 ctaatactat tcatttggca attgggacac gaaatccctt tattttaagt attttatttg
    57421 cttttgttta ttactttatg cgggagcaaa ctgaaaaagg aaaatggatt gggtttaaag
    57481 aaaagttagc gatttttgta ggttctccta ttctcatgtt agcgatggga gtactcaatt
    57541 atgtacggga taatgtccaa gtttcccata caggtttctg ggatatctta cttgacttta
    57601 tctataaaca agggactagt tttggtgttc tggctcgagg ttttctattt aacagtagcc
    57661 tcccttaccg agatttccgt aattttactt ttggtcctgt tcttgattat tttgcaaggg
    57721 ggagtttggg agccattttc ggaggaaaag cctttgaaca tacaaccaat agtgtggaac
    57781 tagctattga tagtaatagt tatgcccaca atctatccta tcttgtcttg aacaaggaat
    57841 acctgaaagg gcatggtatc ggaagtagtt atatcatgga gttgtatacc gactatggta
    57901 tgattggagt ctttctgctt agtttcttac tcggcgtatt atttatagcc atgctgcaag
    57961 tagcctatcg ctcaaggaca atcctatttg ctttatccct actcatcttg aataatctat
    58021 tctttatgcc aagaagcagc ttttcagaaa gtttcttcaa tttatttaca atgcaattct
    58081 ggggaattgt tcttgtgatt atatttatag caaaaatgct tacaaaggaa aactagtatc
    58141 tactaaacaa aggagaaaaa aatcatgttt gaacattatt cagtagctga tttgtttgca
    58201 aatctttata aaaagcgaaa agcaaatatt ttagctctca tcgctttatt tgctctcatt
    58261 gctgtaccat ttacaattaa agcagttagg aataaaaaca ctgtcaaaga tacaacaagt
    58321 tattcaactt atcttatcta taaaatcact cctccaaaag agtcggccaa aacgattttg
    58381 aatcatcaaa ttggtggtta tagtgatttt tatgggaaat tgattgatgg taatttgaat
    58441 ggagcttatc ttttcaatga tgtagaaccc agtgagttga aaaaaattgc cagtgaatta
    58501 gacacgacag aaacaacctt gaaaaattca acgaatgact attggtggaa aaaattgacc
    58561 gtctactata tgattgacga tgcaggggtt ggtgtgaaaa ttttgacatc aagtaaagat
    58621 gccaatgact tgttagagaa aaaaattgat gggttgattg agaaatttaa acatgcctat
    58681 gcaaatgtga aaattgaaaa actggaaacc atcaactcta aagaattgaa cgcaaatggt
    58741 gaaacagcgc ttggcttaaa tgtgaaaaat ctgattcttc gtttagttgt tattggagtg
    58801 gtttgtgtga ttttggttgt gatgggaaat gtgttagttt atctctttaa tccaacaatc
    58861 aatagagtag gtgatttttc tcagtatcaa attgattttg taacagagat tacaacaatt
    58921 gctaacctag cagatgtttt gtcatacaaa aatactggac aggaattgac catcgttagc
    58981 tcaaataaag ctatcctaga taaattgaaa cagagtcaag aagctttaaa aggaatgcat
    59041 tttgtagatt tacaggatgt atcatctctt ttggaaagag atacagtcct tcttgttgaa
    59101 gagtacggag tgactcgtta taagaaattt gagcaaagtc ttcaaattct cagaaactta
    59161 aatcgttcta tcctcggtgt agcaaccttt aaattataag tattctgatg tataaggtct
    59221 tcaaagtcgg ctaagagccg attttgaagg ctttttctat ctgtctgcag aaattttctt
    59281 ttgataaaat cgtaaaaatc tagtataata gatagaactg aaagtatgag gttactagca
    59341 atgaaaatga aacaaattag tgatacaact ttaaaaatca cgatatcttt agaggatttg
    59401 atggatcgtg gaatggagat tgctgacttt ctcgttcctc aagaaaaaac agaagagttc
    59461 ttttatgcta tcttggatga gctagagatg cctgatagct ttctggatac aggcatgttg
    59521 agcttccgtg tgactccaaa acctgataag gtagatgtct ttgtgaccaa gtcaaagatt
    59581 gaccaaaatc tagattttga agacttatcg gatttgccag atatggaaga attggctcaa
    59641 atgtctccag atgaatttat caaaaccctg gaaaaaagca tcgcagacaa aaccaaggat
    59701 gatatcgaag ccattcaatc tcttgagcaa gttgaagcca aggaagaaga acaagagcag
    59761 gctgaacaag aagctgagag taagaaagaa ccttacatct actacatcct ttcttttgct
    59821 aagttggctg acttggtagc ttttgccaag acagtgactt ttgaaatgga aacttctgaa
    59881 ctctacaaaa tgaacgagcg ctattatttg accattttag tggatattga aaatcatcca
    59941 agcccatatc cagcttggct gttggcccgt atgcgcgagt ttgcagagga tagtgatatc
    60001 agtcgctcag tcttacaaga gtatggtcaa gttttgatga gtcacgatgc agtgctcaat
    60061 ctgcaaaaaa tcggctaatc ttttctggaa agctattttc agattttaag aagagcgaat
    60121 cgtctgattc gttttttctt tttatactga aatagtgatt tactataata ggaattttca
    60181 caaaattctg ttataatggc tatattagaa aatttcgagg agataaagat gacagttaaa
    60241 attgctttac taggatttgg taccgttgca agtggtgtgc ctttcctcct aaaggaaaat
    60301 ggaggaaaaa tcaatcaatc agcacattca gatatcaaag ttgctaaggt attggtcaag
    60361 gatgaagatg aaaaaaatcg cttgcttgca gcagggaatg actttaactt tgtaaccaat
    60421 gtggatgata ttttatcaga ccaggatatt actatcgtag tggaattgat ggggcgtatt
    60481 gagcctgcta aaacctttat cactcgtgcc ttggaagctg gaaaacacgt tgttactgct
    60541 aacaaggacc ttttagctgt ccatggcgca gaattgctag aaatcgctca agctaacaag
    60601 gtagcacttt actacgaagc agcagttgct ggtgggattc caattcttcg tactttagca
    60661 aattccttgg cttctgataa aattacgcgc gtgcttggag tagtcaacgg aacttccaac
    60721 ttcatggtga ccaagatggt ggaagaaggc tggtcttacg atgatgctct tgcggaagca
    60781 caacgtctag gatttgcaga aagcgatccg acgaatgacg tagatgggat tgatgcagcc
    60841 tacaagatgg ttattttgag ccaatttgcc tttggcatga agattgcctt tgatgatgta
    60901 gtccacaagg gaatccgcaa tatcacacca gaagacgtag ctgtagctca agagcttggt
    60961 tacgtagtga aattggttgg ttctattgag gaaacttctt caggtattgc tgcagaagtg
    61021 actccaacct tcctacctaa agcgcaccca cttgctagtg tgaatggcgt aatgaacgct
    61081 gtctttgtag aatctatcgg tattggtgag tctatgtact acggaccagg tgcgggtcaa
    61141 aaaccaactg caacaagtgt tgtagctgat attgtccgta tcgttcgtcg tttgaatgat
    61201 ggtactattg gcaaagactt caacgaatat agccgtgact tggtcttggc aaatcctgaa
    61261 gatgtcaaag caaactacta tttctcaatc ttggctccag actcaaaagg tcaggtcttg
    61321 aagttggctg aaatcttcaa tgctcaagat atttccttta agcaaatcct tcaagatggc
    61381 aaagagggtg acaaggcgcg tgtcgttatc atcacacaca agattaataa agcccagctt
    61441 gaaaatgtct cagctgaatt gaagaaggtt tcagaattcg acctcttgaa taccttcaag
    61501 gtgctaggag aataagatga agattattgt acctgcaacc agtgccaata tcgggccagg
    61561 ttttgactcg gtcggtgtag ctgtaaccaa gtatcttcaa attgaggtct gcgaagaacg
    61621 agatgagtgg ctgattgaac accagattgg caaatggatt ccacatgatg agcgtaatct
    61681 cttgctcaaa atcgctttac aaattgtacc agacttgcaa ccaagacgct tgaaaatgac
    61741 cagtgatgtc cctttggcgc gcggtttggg ttcttccagc tcggttatcg ttgctgggat
    61801 tgaactagcc aaccaactgg gtcaactcaa cttatcagac catgaaaaat tgcagttagc
    61861 gaccaagatt gaagggcatc ctgacaatgt ggctccagcc atttatggta atctcgttat
    61921 tgcaagttct gttgaagggc aagtctctgc tatcgtagca gactttccag agtgtgattt
    61981 tctagcttac attccaaact atgaattacg tactcgcgac agccgtagtg tcttgcctaa
    62041 aaaattgtct tataaggaag ctgttgctgc aagttctatc gccaatgtag cggttgctgc
    62101 cttgttggca ggagacatgg tgaccgctgg gcaagcaatc gagggagacc tcttccatga
    62161 gcgctatcgt caggacttgg taagagaatt tgcgatgatt aagcaagtga ccaaagaaaa
    62221 tggggcctat gcaacctacc tttctggtgc tgggccgaca gttatggttc tggcttctca
    62281 tgacaagatg ccaacaatta aggcagaatt ggaaaagcaa cctttcaaag gaaaactgca
    62341 tgacttgaga gttgataccc aaggtgtccg tgtagaagca aaataaagaa tagaagatag
    62401 gatggggaaa ctcttgacca gagggtttca tatccttttt gtgaaaagaa gtttatactc
    62461 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac agtgttttga
    62521 ggttgcagat agaactgacg aagtcagtaa catatatacg gtaaggtgac gctgacgtgg
    62581 tttgaagaga ttttcgaaga gtattagtta aaaacgtgat aaaggagaaa taaagatggc
    62641 agaaatttat ctagcaggtg gttgtttttg gggcctagag gaatattttt cacgcatttc
    62701 tggagtgcta gaaaccagtg ttggctacgc taatggtcaa gtcgaaacga ccaattacca
    62761 gttgatcaag gaaacagacc atgcagaaac ggtccaagtg atttacgatg agaaggaagt
    62821 gtcactcaga gagattttac tttattattt ccgagttatc gatcctctat ctatcaatca
    62881 acaagggaat gaccgtggtc gccaatatcg aactgggatt tattatcagg atgaagcaga
    62941 tttgccagct atctacacag tggtacagga gcaggaacgc atgctgggtc gaaagattgc
    63001 agtagaagtg gagcaattac gccactacat tctggctgaa gactaccacc aagattatct
    63061 caggaagaat ccttcaggtt actgtcatat cgatgtgacc gatgctgata agccattgat
    63121 tgatgcagca aactatgaaa agcctagtca agaggtgttg aaggccagtc tatctgaaga
    63181 gtcttatcgt gtcacacaag aagctgctac agaggctcca tttaccaatg cctatgacca
    63241 aacctttgaa gaggggattt atgtagatat tacgacaggt gagccactct tttttgccaa
    63301 ggataagttt gcttcaggtt gtggttggcc aagttttagc cgtccgattt ccaaagagtt
    63361 gattcattat tacaaggatc tgagccatgg aatggagcga attgaagttc gttctcgttc
    63421 aggcagtgct cacttgggtc atgttttcac agatggaccg cgggagttag gcggcctccg
    63481 ttactgtatc aattctgctt ctttacgctt tgtggccaag gatgagatgg aaaaagcagg
    63541 atatggctat ctattgcctt acttaaacaa ataaaacaga gagtggggct tcccactttc
    63601 ttcatttcta gaatatgaat agaagggatt tatgaaacac ctattatctt acttcaaacc
    63661 ctacatcaag gaatcaattt tagccccctt gttcaagctg ttagaagctg tttttgagct
    63721 cttggttccc atggtgattg ctgggattgt tgaccaatct ttacctcagg gagatcaagg
    63781 tcatctctgg atgcagattg gcctgctcct tatctttgca gtaattggcg ttttagtggc
    63841 cttgatagct caattttact cagcaaaggc agcagtaggt tttgctaagg aattgacaaa
    63901 cgatctttat cgtcatattc tttccttgcc caaggacagc agagaccgtc tgacaacatc
    63961 tagtttggtc actcgcttga cttcggatac ctaccagatt cagactggta tcaatcaatt
    64021 cctgcgtctc tttttgcgag cgcccattat cgtttttggt gccattttta tggcttatcg
    64081 aatctcaact gagttgactt tctggttctt agtcatggtt gccattttga ccattgtcat
    64141 tgtagggtta tctcgattgg tcaatcctct ctacagtagt ctcagaaaga aaacggacca
    64201 actggttcag gaaacgcgcc agcaattgca agggatgcgg gttattcgtg cttttggtca
    64261 agaaaaacga gagttacaga tttttcaaac ccttaaccaa gtttatgcta gattacaaga
    64321 aaagacaggt ttctggtcta gtttattaac acctctgacc tatctgattg tcaatggaac
    64381 tcttctcgtt attatctggc aaggctatat ttcaattcaa ggaggagtgc tcagtcaagg
    64441 tgctctcatt gctcttatca attacctctt acagattttg gtggaattgg tcaagctagc
    64501 catgttgatc aattccctca accagtccta tatctcagtc aagcgaatcg aggaagtctt
    64561 tgttgaggct ccagaggata tccattcaga gttagaacaa aagcaagcta ccagagataa
    64621 ggttttacaa gtccaagaat tgacttttac ctatcctgat gcggcccagc cttctctgag
    64681 atacatttcc tttgatatga ctcaaggaca aattctaggt atcatcgggg gaactggttc
    64741 tggtaaatca agcttggtgc aactcttact tggactttat ccagtagaca aggggaacat
    64801 tgacctttat caaaatggac gtagtcctct taatttggag cagtggcggt cttggattgc
    64861 ctatgtacct caaaaggtcg aactctttaa aggaaccatt cgttccaact tgactctagg
    64921 tttcaatcaa gaagtatctg accaggaact ctggcaggcc ttggagattg cgcaagctaa
    64981 ggattttgtc agtgaaaagg aaggactctt ggatgctcta gttgaggcag gggggcgaaa
    65041 tttctcaggt ggacaaaaac aaagattgtc tatcgcccga gcagtcttgc gccaagctcc
    65101 gtttctcatc ctagatgatg caacctcggc actggatacc attacagagt ccaagctctt
    65161 gaaagctatt agagaaaatt ttccaaacac gagcttaatt ttgatctctc aacgaacctc
    65221 aactttacag atggcggacc agattctcct cttggaaaaa ggtgagttgc tagctgttgg
    65281 caagcacgat gacttgatga aatccagcca agtctattgt gaaatcaatg catcccaaca
    65341 tggaaaggag gactagaatg aaacgacaaa ctgtaaacca gacgctcaaa cgtttagccg
    65401 tagatttagc aagccatcct ttcctccttt tcctagcctt tctaggaact attgctcaag
    65461 ttggcttatc aatttaccta cctattctga ttgggcaggt cattgaccaa gtcctagtgg
    65521 ctggttcatc accagttttt tggcagattt ttctccagat gctcttggtg gtaataggaa
    65581 atactctggt acaatgggcc aatcctctcc tctataatcg tctaatcttc tcttatacca
    65641 gagatttacg ggagcgaatc atccataagc tccatcgttt accgattgcc tttgtagata
    65701 ggcaaggtag tggagagatg gttagtcgtg taaccacgga catcgaacag ttggcagctg
    65761 gcttgaccat gatttttaac caatttttca ttggtgtttt gatgattttg gtcagtattc
    65821 tagccatgct ccaaattcat ctcctcatga ctctcttagt cttgctgttg acgccactgt
    65881 ccatggtgat ttcacgcttt attgccaaga aatcctatca tctcttccag aagcaaacag
    65941 agacgagggg aattcagact cagttgattg aagaatcgct tagtcagcag actataatcc
    66001 agtccttcaa tgctcaaaca gaatttatcc aaagattgcg tgaggctcat gacaactact
    66061 caggctattc tcagtcagcc atcttttatt cttcaacggt caatccttcg actcgctttg
    66121 taaatgcact catttatgcc cttttagctg gagtaggagc ttatcgtatc atgatgggtt
    66181 cagccttgac cgtcggtcgt ttagtgactt ttttgaacta tgttcagcaa tacaccaagc
    66241 cctttaacga tatttcttca gtgctagctg agttgcaaag tgctctggct tgcgtagagc
    66301 gtatctatgg agtcttagat agccctgaag tggctgaaac aggtaaggaa gtcttgacga
    66361 ccagtgacca agttaaggga gctatttcct ttaaacatgt ctcttttggc taccatcctg
    66421 aaaaaatttt gattaaggac ttgtctatcg atattccagc tggtagtaag gtagccatcg
    66481 ttggtccgac aggtgctgga aaatcaactc ttatcaatct ccttatgcgt ttttatccca
    66541 ttagctcggg agatatcttg ctggatgggc aatccattta tgattataca cgagtatcat
    66601 tgagacagca gtttggtatg gtgcttcaag aaacctggct cacacaaggg accattcatg
    66661 ataatattgc ctttggcaat cctgaagcca gtcgagagca agtaattgct gctgccaaag
    66721 cagctaatgc agactttttc atccaacagt tgccacaggg atacgatacc aagttggaaa
    66781 atgctggaga atctctctct gtcggccaag ctcagctctt gaccatagcc cgagtctttc
    66841 tggctattcc aaagattctt atcttagacg aggcaacttc ttccattgat acacggacag
    66901 aagtgctggt acaggatgcc tttgcaaaac tcatgaaggg ccgcacaagt ttcatcattg
    66961 ctcaccgttt gtcaaccatt caggatgcgg atttaattct tgtcttagta gatggtgata
    67021 ttgttgaata tggtaaccat caagaactca tggatagaaa gggtaagtat taccaaatgc
    67081 aaaaagctgc ggcttttagt tctgaataag ccattctctt ttgaaagttt atggacgaaa
    67141 aaagttgcct tcgagtgact tttttgttac aatagctaga aaaattgttc actgtaatac
    67201 tcaatgaaaa tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcacagcttt
    67261 gaggttgtag ataagactga cgaagtcagt tcaaaacact gttttgaggt tgcagataga
    67321 actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
    67381 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
    67441 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
    67501 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
    67561 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
    67621 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
    67681 cgagatgaca gcaatctcca tgaatggctc aatgactata tttggccagc agaatctgag
    67741 tttactcccg acatgactac caatgcggtc aaagaagccc tgacagagat gctccagtca
    67801 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
    67861 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
    67921 acagaaacaa ctgctgagac tataagtaga actcgatcca tcatagacga aatcttaaaa
    67981 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
    68041 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
    68101 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
    68161 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
    68221 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
    68281 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
    68341 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
    68401 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
    68461 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
    68521 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
    68581 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
    68641 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
    68701 acagtagaac tttaaaagaa aaattacgaa aaattttaaa aaaagtttgc aaaaatcttg
    68761 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
    68821 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
    68881 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
    68941 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
    69001 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
    69061 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
    69121 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
    69181 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
    69241 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
    69301 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
    69361 cgcgaaggac ttctttctat gctcctttct gtacttcaag caccagtgcg caacgttgct
    69421 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
    69481 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
    69541 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
    69601 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
    69661 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
    69721 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat cactggtctt
    69781 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
    69841 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
    69901 cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt ctttgagagc
    69961 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
    70021 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
    70081 gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcgt gaagagtcat
    70141 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
    70201 caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt cttggaggga
    70261 caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat tataagctcc
    70321 ccaaactttt atttgagagt gaacggtata agaatatgaa actggaggtt aaggtggttt
    70381 actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt gatgaggatg
    70441 gggctattta tttgatttat tccaattcaa atttgatggc acttttaggc tgttcaaagt
    70501 caaaattact ctccatgtga gtttgaagtg atatttttag atgattacca taaaaaacat
    70561 aactacccac tattttacga atcctatctt caaaacgtta tggaattcct tgaaagtcaa
    70621 gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt ttttgtttta
    70681 tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca agtaactgta
    70741 aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga ttccttaatt
    70801 tattagattc cttaatcgtg tcagaatatc aaatggaacc gaatctttgg gaggtctccc
    70861 atgattgatc tctatctaag taaaaataga caaagaaatc aacttctttt agatttcttc
    70921 caaaactatg gcatagaggt atcttgtcat tcagtttctg aaatgacaaa ggacaaatta
    70981 attgagatga tgagctattc ttcagattgt tttgagtttt tatctcccaa tttattacga
    71041 tttaagaacc gtgacaatct aagattaacg gatttcgttg agataatttt aaaaaatcct
    71101 gaactaacca tcagacttcc tcttgcggtt tcaaataagc gagtttatcc aagtctgaat
    71161 ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta catggcgcaa
    71221 acacattatt tatctaacta aaggagaagc aatatggctg aacgattttg ggagaacttg
    71281 tccattattt tggctgaaag aaatatcagc tggattgagt taaccagaaa aatgtttgcg
    71341 ggagagtttc actatccaag tgaattgaat cgtttgtatc aaaagattcg ccactagaag
    71401 atggaacaat gaatgcctca aagtccatgg gtagaaagga ttgtgcaggt attagattta
    71461 gattatgaag atttatttcg gaggtaacta tgaaaagaat aattccagtt tatatattcc
    71521 aacaagtaaa tgtcctattg gtatctctat acttattgaa atttctttgt atcggtgagt
    71581 taactatact acagattctc tatggttcgt cactcatttc ttttttatgg atgtatggcc
    71641 aacgcaaaca agcgcataag gtcaatatga aatctaggat gaaatggctt ggtgttgaat
    71701 ttgttagcct actgattata agtctatgtt ttagtctgat tcatgctcaa ggaagcacga
    71761 atcaagcaaa cttaattggc cttcaacatc aaattccttg gttttcattt ttattgttct
    71821 taatcaatgc gagtatggtt gaagaatttc tgtatcgaga aattttatgg aatttggtca
    71881 gaaaattaga tatcagagtt gctttgacaa gtgttttatt tgccttagca catcatccag
    71941 gaaccattat agcttggtgt ttgtatgtat cgctggggat gtttttaggg cttgtacgct
    72001 acaaattgga cttatggggc agtatggggc tacatttggt gtggagccta ctagtttata
    72061 gtttgctgct tttttaaaat aggtaacctg atttttaggt aacttctaaa actaacttcc
    72121 agttttggga gagagatgga agttactttg aaaagttacg gaaacattat tttctacgtg
    72181 acaacattgt atcattgctt gcattttact gctggagaga gtataatgaa ggtggataaa
    72241 gcacttaatc ccaaaaattt aaataggagg agttagctat ggcagaagaa gtattaaatc
    72301 ttcaattagt atctgttcaa gttgacgaaa cagatgaagt tgatggaatg cgatttagta
    72361 cattcagtac aaaccgttgc ggtaactgga gtgcttttag ttgggaaaat tgttaattca
    72421 tttaaattgt aaactttagg gattctctgg agttatggat ctcgttccaa tatgtgcacg
    72481 ttggaatgtc agtgcttata tggggggaat ccaaaggatt ctcccttttt attttaataa
    72541 gtctgtctag ctatagatat attaagtttg atagaatttc ttggagattt tgttatggat
    72601 tataatttca atttggagca tcctttcttt ttcactaata atgattatag tacagatact
    72661 agcataaagt actaagtaag tctgcctttt aattggcacg aagtaatgaa taatgatgag
    72721 tgggtttatc aataccctat tggaaaattt gttgaaagac aagggtggaa aatacacatt
    72781 agttcagagt ataatagttc acacgaattg ttacaagatg tagcaaaaat ttgccatgaa
    72841 atgcgaattc catttaaaca tcttagtaca gaagacaaat ttatcatgcg aaacgggaaa
    72901 ttggttagtc gaggattttc tggtaaattt attacatgtt atccaaatca aaatgaatta
    72961 gagtcggttt tgcaaaggtt agaaagtgcc ttaaagcaat ataatgggcc atatatttta
    73021 agcgataaac gttgggatga agcaccaata tatctgaggt atggtgtgtt taggccgtca
    73081 agggatgatg aaaagaaggt tgttattgat gaattaattg ttggcgatga agttgttaaa
    73141 gatgaacgtt taccagtatt taaaattcca aaaggtatag tgccccctga ctttttgaat
    73201 aaatggcttg acaagaaaga taaaaaacag ggagactttc cctttattat agataatgca
    73261 attagatttt caagcagtgg tgggatatat aatgctagac taaaagaaga tgggaaaaaa
    73321 ataattttaa aagaggctag accgtataca ggtctaggat ttgatggtac ttattcttca
    73381 gagagattag cttcggagtg caaagcacta aaaattctaa atgaatggag tgagatgcct
    73441 aaaatatact ggtacggtaa gatctgggag cacaccttct taggaattga acatatgaag
    73501 ggcgttccac taaatagatg ggttaccaat aattttcctt tatatgaagt tgttgataag
    73561 accaaagatt atctattgag agtttcaaag atagtagaaa aactcatcga tttaacgaat
    73621 aagtttcatt ctgaaaatgt atatcatcaa gatttacatt taggaaatat cttggttaag
    73681 gatgaagatg agattagtat aatagactgg gaacaggctg tcttttcgaa tgatgaaaaa
    73741 gttgtacata aagttgcagc ccctggtttt agagcatggc gagaaacact tcccagtgag
    73801 atagattggt atggtattag acaaatagct cattatttat acatgccact agtaactaca
    73861 tcggatttga catacaacta tgtaagtcaa accaggatag aaggaaaaaa actatttgag
    73921 tctttgggtt atacaagaga acatatagat tatgtagaaa gtttattgtc atatctagat
    73981 tctaaatgtc cacagattga gaatatttcc aggaaaaaag ttttaaaacc catgcatgag
    74041 attagaacta tcgagagtga gcaagatata caagatttta ttataaaagc ttttctttta
    74101 gtgaactgat aggtattttc ttagcaaacg ataaagtttt agggccgata caatcaattg
    74161 cctattcatt aaataagata aatacaacca aagatttaag gaaaccgttt ttaaaatact
    74221 taagtggaga gaagaatttt atagacgctg aacatgataa taacggactg tatacttcat
    74281 caatagatgt gatacacatg aaagatgttg tatattctat tacaccagaa aataaattaa
    74341 gtattgactt ctcatttaag tcaccattta gggtattatt aacaggaact tctggtagtg
    74401 ggaaaacaac gattttaaat ttaattaatg gttctttaaa gccacaaaaa ggttatgtaa
    74461 atttgttatc acatgggaaa aagagttcag attcaatacc aacagttgat cagacaccat
    74521 atatttttga cactactatt cgtgagaacg taactttatt tcaaaatgaa tatttttcag
    74581 atgatcagat aattgaggtg ttaaaaaagg taaatctata tgaagaatta gaaaagatag
    74641 atatactaaa ttatcaatgt ggtgaaaatg gtagtaattt gtctggaggt caaaaacaaa
    74701 aaatagcttt agctagagct ctgattagaa ataataaagt gtacttattt gacgaaatat
    74761 cagctaattt agataatgat aattcaaatt ccatacatga tattctgttc aatttaggta
    74821 tttcatttat tgaagtttca catcattatg acttaaatga caagagatac actgatatat
    74881 aaattggaaa atggaacact tttcaaaatt aagtgattgg aggcaagaat atggataaag
    74941 attatatatt aaaagtgaaa gggctgtatc atcaattttt actgggaaac aataaaacgt
    75001 tgcaagtgct gaaaaatgtt tctctttctg cttcgagagg agaatttata agtattctag
    75061 gaattagtgg ttctggaaag tcaactttat taaaatgtat ttctagtttg cttgaaccaa
    75121 caagtgggga agtaatttta aatggaatca acccctataa aatcagaaat gcaaaattgt
    75181 caagtataag acgtaacgaa gtatctttta tatttcaagc atacaattta ataccttccc
    75241 tgccggtaat agaaaatata gcacttcctt tgcgattatc acaaaaaaaa ttaactatta
    75301 aaaatgtaga aaacttactc aaaagaatga agtttaatgc tggcttaaac gattttgttg
    75361 gaactctgtc tggtggagaa caacagaagg ttgctatagc tagagcggtt attgctgata
    75421 gtgatataat atttgctgat gagccaactg gggctttaga cagcgtttct cgtgaagtaa
    75481 tttttgaatt attgagagag ttagtagggg cgggtaagtg tgtaattatg gtaacgcacg
    75541 atatagaatt ggcctcgaaa actgatcgtg cattaatatt gaaagatgga aaaattttca
    75601 aagaacttca tagacctagc ggggaagagt tgtataaaat cttagaggta caatcaacta
    75661 cggaggaata gagatgctca gattagttta ctatcaattt ttacataata agaaacaatg
    75721 gttaggcgtt tcaccagtaa tttttgtttc gagtttagtt atgggattgg ctgttaatgg
    75781 ggtaattaat gttgagaata attcgcaagt atttgtcgga cttccagatc ctaaaccaat
    75841 ttttatgttt ccgatagtat tcggaggagt aacattattc tttgtgctct ctaacataat
    75901 aaatatgttg gttgaaattt ttagagatga ttacgaactt ctggaggtgt tgggagcaag
    75961 tctccttcaa ctatcatttc ttgtgggggg acagattttt atcatttcct cgattattag
    76021 ttttattgca tatctatgct ctatatttgt tacgtcaaat tattattatt ttttacaata
    76081 ctttttcggg gaaaatatat tacctgatat ccaatttcaa acgagtgctg ttggatgtat
    76141 cattacagta gtgttgattt catttttagc ctttctaagt ggttgctttt atacgttcaa
    76201 gaagattaga aataggaaga gttctaaaat aaggcatgtt ctttcaatag taaaaagaat
    76261 actgctattg gctggtttta gtgttatctg gttgctttct ttgcaacaaa ttttccaaga
    76321 tagcacaatt ttagcgaagg cccagataat attcaatatt gtaatcttag atattgtgat
    76381 tatttatcaa ttatctcctt ttatacagtc atgttttatc aaactacttt ctataattat
    76441 atttagaaat aattttatgt tcattgtttc gaagtggaat ttactatatc gtaagcctta
    76501 tataaaatct atcagtgctg caattacagg agctatatta ctaatttcta gttttcaaat
    76561 gatttctcag aatatactat ctcaatttca agatgacagt gatttagagc taaaagtggc
    76621 atttattgtc tatgtaggag caccaatttt gatagtactt gcaaatatta tttcaattgc
    76681 atttttgtca tcgcatcaag aaaggattga gattcagcaa tttgaaattt taggaacttc
    76741 taattaccag atggttaaga ttaaagttgg tgaggctata tttttgacat ttgttacttc
    76801 attaattgca tttttactta acattaaaat tatggcttta atatactact ctttagggga
    76861 tattttaata gatgatatga atcttttggg gttaatactt ccaaatttta tagtgtctat
    76921 tattttattt attttaatat ttattactaa aagttcctat tttatcttta agaatgcaaa
    76981 aattatttct taaaaatttg taagttttcg ctatataaaa tagttaaatc tattttgtat
    77041 cattgcttgc attttactgg tggagagaat ataatgaggg tggataaagt acttaatccc
    77101 aaaaatttaa ataggaggag
//
LOCUS       DAVIME010000003        69348 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVIME010000003 DAVIME010000000
VERSION     DAVIME010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.003"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(1..346)
                     /locus_tag="VV588_000202"
                     /pseudo
     CDS             complement(1..346)
                     /locus_tag="VV588_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239016.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
     gene            complement(365..661)
                     /locus_tag="VV588_000203"
     CDS             complement(365..661)
                     /locus_tag="VV588_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082626.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(645..2804)
                     /gene="pfbA"
                     /locus_tag="VV588_000204"
     CDS             complement(645..2804)
                     /gene="pfbA"
                     /locus_tag="VV588_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU7082627.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3935..5161)
                     /locus_tag="VV588_000205"
     CDS             complement(3935..5161)
                     /locus_tag="VV588_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU7082628.1"
                     /translation="MPNYNIPFSPPDITEAEITEVVDTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSIYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAASRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5204..5896)
                     /locus_tag="VV588_000206"
     CDS             complement(5204..5896)
                     /locus_tag="VV588_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU7082629.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(6069..7820)
                     /locus_tag="VV588_000207"
     CDS             complement(6069..7820)
                     /locus_tag="VV588_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082630.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATMVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGV
                     TYHKMYSLQAGAMADTL"
     gene            complement(7810..9555)
                     /locus_tag="VV588_000208"
     CDS             complement(7810..9555)
                     /locus_tag="VV588_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082631.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9761..10057)
                     /locus_tag="VV588_000209"
     CDS             complement(9761..10057)
                     /locus_tag="VV588_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU7082632.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10210..10667)
                     /locus_tag="VV588_000210"
                     /pseudo
     CDS             complement(10210..10667)
                     /locus_tag="VV588_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10801..11628
                     /gene="xth"
                     /locus_tag="VV588_000211"
     CDS             10801..11628
                     /gene="xth"
                     /locus_tag="VV588_000211"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU7082633.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11640..11777
                     /locus_tag="VV588_000212"
     CDS             11640..11777
                     /locus_tag="VV588_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU7082634.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLLKSV
                     N"
     gene            11888..12016
                     /locus_tag="VV588_000213"
     CDS             11888..12016
                     /locus_tag="VV588_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU7082635.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12399..12494
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12894..13475
                     /locus_tag="VV588_000214"
     CDS             12894..13475
                     /locus_tag="VV588_000214"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU7082636.1"
                     /translation="MKLLEDRILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13475..14737
                     /locus_tag="VV588_000215"
     CDS             13475..14737
                     /locus_tag="VV588_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU7082637.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPLDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14788..15249)
                     /locus_tag="VV588_000216"
     CDS             complement(14788..15249)
                     /locus_tag="VV588_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU7082638.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(15246..16010)
                     /locus_tag="VV588_000217"
     CDS             complement(15246..16010)
                     /locus_tag="VV588_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEU7082639.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(16191..16595)
                     /locus_tag="VV588_000218"
     CDS             complement(16191..16595)
                     /locus_tag="VV588_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU7082640.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16665..18146)
                     /locus_tag="VV588_000219"
     CDS             complement(16665..18146)
                     /locus_tag="VV588_000219"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU7082641.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(18165..19343)
                     /locus_tag="VV588_000220"
     CDS             complement(18165..19343)
                     /locus_tag="VV588_000220"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU7082642.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKCAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19508..20515
                     /gene="galR"
                     /locus_tag="VV588_000221"
     CDS             19508..20515
                     /gene="galR"
                     /locus_tag="VV588_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU7082643.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20561..21598)
                     /locus_tag="VV588_000222"
     CDS             complement(20561..21598)
                     /locus_tag="VV588_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU7082644.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21599..21952)
                     /locus_tag="VV588_000223"
     CDS             complement(21599..21952)
                     /locus_tag="VV588_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU7082645.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(22196..23086)
                     /locus_tag="VV588_000224"
     CDS             complement(22196..23086)
                     /locus_tag="VV588_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU7082646.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            23219..23755
                     /locus_tag="VV588_000225"
     CDS             23219..23755
                     /locus_tag="VV588_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU7082647.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23921..24727)
                     /locus_tag="VV588_000226"
     CDS             complement(23921..24727)
                     /locus_tag="VV588_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU7082648.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(25072..26592)
                     /locus_tag="VV588_000227"
     CDS             complement(25072..26592)
                     /locus_tag="VV588_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU7082649.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLNGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITENQMSQLNYQVGVEGKSAEQVAKEFLQEQGLLKK"
     gene            complement(26585..27313)
                     /locus_tag="VV588_000228"
     CDS             complement(26585..27313)
                     /locus_tag="VV588_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082650.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(27328..28092)
                     /locus_tag="VV588_000229"
     CDS             complement(27328..28092)
                     /locus_tag="VV588_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU7082651.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(28096..28539)
                     /locus_tag="VV588_000230"
     CDS             complement(28096..28539)
                     /locus_tag="VV588_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU7082652.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(29221..29517)
                     /locus_tag="VV588_000231"
     CDS             complement(29221..29517)
                     /locus_tag="VV588_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU7082653.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29539..30603)
                     /gene="pepA"
                     /locus_tag="VV588_000232"
     CDS             complement(29539..30603)
                     /gene="pepA"
                     /locus_tag="VV588_000232"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU7082654.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPYVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            31004..31705
                     /locus_tag="VV588_000233"
     CDS             31004..31705
                     /locus_tag="VV588_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEU7082655.1"
                     /translation="MTKTILVTGGTSYISSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNAAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            32128..33087
                     /locus_tag="VV588_000234"
     CDS             32128..33087
                     /locus_tag="VV588_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082656.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            33077..34033
                     /locus_tag="VV588_000235"
     CDS             33077..34033
                     /locus_tag="VV588_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU7082657.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQVLIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            34030..34782
                     /locus_tag="VV588_000236"
     CDS             34030..34782
                     /locus_tag="VV588_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU7082658.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34878..35843
                     /locus_tag="VV588_000237"
     CDS             34878..35843
                     /locus_tag="VV588_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7082659.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(36068..36310)
                     /gene="yidD"
                     /locus_tag="VV588_000238"
     CDS             complement(36068..36310)
                     /gene="yidD"
                     /locus_tag="VV588_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU7082660.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(36310..37032)
                     /locus_tag="VV588_000239"
     CDS             complement(36310..37032)
                     /locus_tag="VV588_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU7082661.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVVNKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(37019..37588)
                     /locus_tag="VV588_000240"
     CDS             complement(37019..37588)
                     /locus_tag="VV588_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU7082662.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37607..38335)
                     /locus_tag="VV588_000241"
     CDS             complement(37607..38335)
                     /locus_tag="VV588_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU7082663.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(38335..39075)
                     /gene="xerD"
                     /locus_tag="VV588_000242"
     CDS             complement(38335..39075)
                     /gene="xerD"
                     /locus_tag="VV588_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU7082664.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(39066..39527)
                     /locus_tag="VV588_000243"
     CDS             complement(39066..39527)
                     /locus_tag="VV588_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU7082665.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39524..40045)
                     /locus_tag="VV588_000244"
     CDS             complement(39524..40045)
                     /locus_tag="VV588_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU7082666.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(40021..40992)
                     /locus_tag="VV588_000245"
     CDS             complement(40021..40992)
                     /locus_tag="VV588_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU7082667.1"
                     /translation="MTNKIYEYKDDRDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40989..41783)
                     /gene="racE"
                     /locus_tag="VV588_000246"
     CDS             complement(40989..41783)
                     /gene="racE"
                     /locus_tag="VV588_000246"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU7082668.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41990..42238)
                     /locus_tag="VV588_000247"
     CDS             complement(41990..42238)
                     /locus_tag="VV588_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU7082669.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42494..44119)
                     /gene="treC"
                     /locus_tag="VV588_000248"
     CDS             complement(42494..44119)
                     /gene="treC"
                     /locus_tag="VV588_000248"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU7082670.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMTDYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(44297..46264)
                     /gene="treP"
                     /locus_tag="VV588_000249"
     CDS             complement(44297..46264)
                     /gene="treP"
                     /locus_tag="VV588_000249"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU7082671.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATNPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46449..47159
                     /gene="treR"
                     /locus_tag="VV588_000250"
     CDS             46449..47159
                     /gene="treR"
                     /locus_tag="VV588_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU7082672.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(47192..47995)
                     /locus_tag="VV588_000251"
     CDS             complement(47192..47995)
                     /locus_tag="VV588_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU7082673.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMNLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(48008..48901)
                     /locus_tag="VV588_000252"
     CDS             complement(48008..48901)
                     /locus_tag="VV588_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082674.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLAGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            complement(48913..49773)
                     /locus_tag="VV588_000253"
     CDS             complement(48913..49773)
                     /locus_tag="VV588_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU7082675.1"
                     /translation="MSQFITHQSLYATREGFVDKLAKQGYVEGENIEIDLQNAQGEQR
                     NLKTISQQLAESSDVVLAIARPSAQSLANTTQTTPVIFSAVTDPVSAKLVESREHPGG
                     NVTGTSDQSSDAISTQINLIKKVLPKAKTIGILYTQSEPNSVVQKDEAKRLLKEKGFT
                     VVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISLTMETVKQVSIKHKVPVFGGSTE
                     MIAVGGLYNYGTNYEELGRQTARMLIRVLKGEKPENIAVELPEKLELHTNQEMADALG
                     IDISKLEGKE"
     gene            complement(50340..51266)
                     /locus_tag="VV588_000254"
     CDS             complement(50340..51266)
                     /locus_tag="VV588_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082676.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(51277..52344)
                     /locus_tag="VV588_000255"
     CDS             complement(51277..52344)
                     /locus_tag="VV588_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082677.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            complement(52353..53279)
                     /locus_tag="VV588_000256"
     CDS             complement(52353..53279)
                     /locus_tag="VV588_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082678.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            complement(53279..54775)
                     /locus_tag="VV588_000257"
     CDS             complement(53279..54775)
                     /locus_tag="VV588_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082679.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            complement(54842..56821)
                     /locus_tag="VV588_000258"
     CDS             complement(54842..56821)
                     /locus_tag="VV588_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7082680.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            complement(57507..58700)
                     /locus_tag="VV588_000259"
     CDS             complement(57507..58700)
                     /locus_tag="VV588_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU7082681.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            complement(58838..60280)
                     /gene="gtfA"
                     /locus_tag="VV588_000260"
     CDS             complement(58838..60280)
                     /gene="gtfA"
                     /locus_tag="VV588_000260"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU7082682.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTMLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            complement(60580..61413)
                     /locus_tag="VV588_000261"
     CDS             complement(60580..61413)
                     /locus_tag="VV588_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU7082683.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            complement(61427..62293)
                     /locus_tag="VV588_000262"
     CDS             complement(61427..62293)
                     /locus_tag="VV588_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7082684.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            complement(62307..63566)
                     /locus_tag="VV588_000263"
     CDS             complement(62307..63566)
                     /locus_tag="VV588_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU7082685.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            complement(63658..65820)
                     /locus_tag="VV588_000264"
     CDS             complement(63658..65820)
                     /locus_tag="VV588_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU7082686.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHITLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            65928..66788
                     /locus_tag="VV588_000265"
     CDS             65928..66788
                     /locus_tag="VV588_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU7082687.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIS
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQSPSHTRKEYS
                     QYQLVRKATL"
     gene            66785..67720
                     /locus_tag="VV588_000266"
     CDS             66785..67720
                     /locus_tag="VV588_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU7082688.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEINSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(67846..67933)
                     /locus_tag="VV588_000267"
     tRNA            complement(67846..67933)
                     /locus_tag="VV588_000267"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67897..67899),aa:Ser,seq:gct)
     gene            complement(67940..68013)
                     /locus_tag="VV588_000268"
     tRNA            complement(67940..68013)
                     /locus_tag="VV588_000268"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(67977..67979),aa:Ile,seq:gat)
     gene            complement(68049..68119)
                     /locus_tag="VV588_000269"
     tRNA            complement(68049..68119)
                     /locus_tag="VV588_000269"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68085..68087),aa:Gly,seq:tcc)
     gene            complement(68139..68211)
                     /locus_tag="VV588_000270"
     tRNA            complement(68139..68211)
                     /locus_tag="VV588_000270"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68176..68178),aa:Phe,seq:gaa)
     gene            complement(68215..68288)
                     /locus_tag="VV588_000271"
     tRNA            complement(68215..68288)
                     /locus_tag="VV588_000271"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68252..68254),aa:Met,seq:cat)
     gene            complement(68299..68388)
                     /locus_tag="VV588_000272"
     tRNA            complement(68299..68388)
                     /locus_tag="VV588_000272"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68350..68352),aa:Ser,seq:tga)
     gene            complement(68399..68472)
                     /locus_tag="VV588_000273"
     tRNA            complement(68399..68472)
                     /locus_tag="VV588_000273"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68436..68438),aa:Ile,seq:cat)
     gene            complement(68486..68559)
                     /locus_tag="VV588_000274"
     tRNA            complement(68486..68559)
                     /locus_tag="VV588_000274"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68523..68525),aa:Met,seq:cat)
     gene            complement(68565..68638)
                     /locus_tag="VV588_000275"
     tRNA            complement(68565..68638)
                     /locus_tag="VV588_000275"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68602..68604),aa:Pro,seq:tgg)
     gene            complement(68654..68727)
                     /locus_tag="VV588_000276"
     tRNA            complement(68654..68727)
                     /locus_tag="VV588_000276"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68691..68693),aa:Arg,seq:acg)
     gene            complement(68737..68822)
                     /locus_tag="VV588_000277"
     tRNA            complement(68737..68822)
                     /locus_tag="VV588_000277"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68786..68788),aa:Leu,seq:taa)
     gene            complement(68830..68901)
                     /locus_tag="VV588_000278"
     tRNA            complement(68830..68901)
                     /locus_tag="VV588_000278"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68867..68869),aa:Gly,seq:gcc)
     gene            complement(68924..68996)
                     /locus_tag="VV588_000279"
     tRNA            complement(68924..68996)
                     /locus_tag="VV588_000279"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68961..68963),aa:Thr,seq:tgt)
     gene            complement(69015..69096)
                     /locus_tag="VV588_000280"
     tRNA            complement(69015..69096)
                     /locus_tag="VV588_000280"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(69060..69062),aa:Leu,seq:tag)
     gene            complement(69102..69174)
                     /locus_tag="VV588_000281"
     tRNA            complement(69102..69174)
                     /locus_tag="VV588_000281"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(69139..69141),aa:Lys,seq:ttt)
     gene            complement(69199..69271)
                     /locus_tag="VV588_000282"
     tRNA            complement(69199..69271)
                     /locus_tag="VV588_000282"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(69236..69238),aa:Asp,seq:gtc)
     gene            complement(69274..69346)
                     /locus_tag="VV588_000283"
     tRNA            complement(69274..69346)
                     /locus_tag="VV588_000283"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(69311..69313),aa:Val,seq:tac)
BASE COUNT        20703 a        15592 c        12791 g        20262 t
ORIGIN      
        1 ggtctaaaaa tctctcatcc aacgaaccta tccagtaccc actcggttga ttagataatt
       61 ttctgatttt ttgtaaaata atttttttat ttaaaacact atttgtacca attggatctt
      121 ttatctcatt tttccctttt tcaaataagt tatctactct atgatccgtt atttccattt
      181 cgtttactaa catgacgcag tcacctagca tcatatactc caactttttt tctgaaagtt
      241 tagcaaatat aaaagcaaat gttggtaagc gataatatag tatattgaaa ctagaatagt
      301 acacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatt gatttgtcct
      361 attattattt cattttatta tactctgtta attcatatga gtttaaaccg atttcatctt
      421 taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct ttacaattaa
      481 ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct atctcctctt
      541 tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt tgtgaaccta
      601 caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt atctttacca
      661 taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt taagaatagt
      721 tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac tatttcttta
      781 gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata gtttacttct
      841 tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt atctttactt
      901 gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt agattgtttt
      961 tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac aattttgtaa
     1021 agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac aggttctttc
     1081 ccatttgcat tagatttgat gaatgatata tacttaccgg ataaattata aaattggtta
     1141 tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt acccccgaat
     1201 atactattct ctgagactac taaattatca ctaactcgta ataattcaat atttggttgt
     1261 tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc tgatactttt
     1321 cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg atcggcaata
     1381 ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc tttagtgttt
     1441 ttatagctat aagcatttac taaagctgct ccgctttctc gataatgtac actctctcct
     1501 ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc tgtaaaacgt
     1561 acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt agaggggttc
     1621 tgtgtcgaca atgtttgata gtgtgtgcca attgctgtta ctaattcccc agatttatca
     1681 cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc atcatcattc
     1741 aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc cttacttatg
     1801 atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga attatcaact
     1861 aatacatttt tcgaacctgc aatttgaata gcatgccctt gataactatc cttgaatgtt
     1921 acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga agaatttata
     1981 agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat atcaatcgta
     2041 ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc atcatccgta
     2101 aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc atttagaatt
     2161 gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat ttcttttact
     2221 aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc tgcagcatct
     2281 attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc accataatct
     2341 tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact tataacatct
     2401 tccttataac tcttattttc attagtagat gttactgtag attcaactgt tctgttgtct
     2461 aattgtgaat tggaacgaat agtaccatta gagctgatgc tattaacact taacgaatta
     2521 tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt ctgattaaca
     2581 gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt agccatcggt
     2641 gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat tgaaattgcc
     2701 aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc attaggaaca
     2761 aaatatttca tcagaacctc caattttttt actattttta acaattgatt attacttttc
     2821 ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc caaattgaat
     2881 tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc tcttcaaact
     2941 aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct atagtagact
     3001 gaaactataa tagtacacct ctacttctaa aacattgtta gaaatcgatt tgactatccc
     3061 gatcgatttg tcctattctt atttcctttt actatatcta caacctcaaa gcagggtttt
     3121 gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa agtgatgcta
     3181 tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat tgatatgttg
     3241 taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg gatatttacc
     3301 ttaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc ttaaatagac
     3361 cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct aaaatactgg
     3421 aatagggcat ataggtaatc gtagacaagt gttttataga ttgtctcgca ggagatctaa
     3481 tgatgtatag caagcatcac taaacatatg ggatatttgc gttattataa tatcaacatg
     3541 ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac aaaactttga
     3601 acaatattct gaaaacaaaa aaaagacgct agtttccaca atctcactca tggaaactca
     3661 cgtctttcaa aaaatagggt gaattgaaaa ctagaacaag acactagatt ttctaaatga
     3721 tgtctagtaa ggattctaaa tgctatacca aattgctcac atcttatttc aaaccacggg
     3781 actcccacaa gaaaggaaaa tcctataaaa attctctctc tgaggagaaa gaggcctcaa
     3841 ctacaggtgt aaactattat caattgaaaa caacagtttt tacactcaat tagacttttt
     3901 aggggcagga tcactttcgc ttgactgtag tttgtcattt ttttgataaa gttagcactt
     3961 tttcagaaac tgttttgaaa gtctcaatga tatagtctac ttcttcatcg cttaatttag
     4021 tatgaagagg gagggtaatt tcattctcaa agaaggcata ggccttagga tagttcgtca
     4081 tatcaaatcc aagattctta taggctgtca agagaggaag cggtttgtag tgaacattac
     4141 ttgcaattcc tgctttagcc aattcttgga tgatgaggtt gcgttcttct aggcttgctc
     4201 cttctacacg ggtgatgtag aggtggcgtg aagattcgac agtttcagtc ttgtgtgcca
     4261 aaggatggat gcgagaagct gcaaaaccac tatcatagcg gtccacaatg tccttacggc
     4321 gttgcaacaa acttggatag cggtccaatt gtaccaaacc aagtgaagcc atgatatcgg
     4381 tcatgttgca cttataggct ggtgtaacga tatcgtattc ccatgacccc agttgcatct
     4441 tggcaagagc atccttagtt tgcccgtgaa gggaaaggat ttggaattcc ttgtacatct
     4501 cttcgtcatc aatcactgga ttggctttcc aagtcgcact tccaccttct gccgttgtaa
     4561 agttcttaac tgcatggaat gagaaggaag taaagtcagc gatagaacca gaaggttgtc
     4621 ctttataaat agatcccaaa gcgtgggcac tatcagagac aatgacaata cggttaaagg
     4681 ccttttgcca cttgcttgaa gcggtaaaga agtcacgttt tttctccacg acttggaaca
     4741 aacggtcata atcgcaaaca atccctgcga gctctactgg aataatcacc ttagttttct
     4801 cagtgatagc ttgctcaagc aggtcatagt ccatctcaaa cgtatctgct tggatatcca
     4861 ccatgacagg ggttgctccc acgtgcgtaa tgacactaca tgaagccgta taggtcatgg
     4921 ctggaacgat gacttcatca ccaggtccca cttccaaaac gcgtaaaatc aactccagag
     4981 cggctgtcgc agagttgaga caaacagtct taggtgtctg tgtgtaaaga gacaagcggc
     5041 gctccagttc ttttgtttta ggacctgttg tgatccaacc agaacgcagg gtatccacta
     5101 cttcagtaat ttctgcttct gtgatatcag gcggtgaaaa tggaatattg taatttggca
     5161 ttgatttgct ccttttatct gtactcattt tcttatgact actttatttt agtacctcaa
     5221 acacggtttg aaacatgatt ttgatgtccc caaagaaact aaactctcgg agataggcga
     5281 ggttatagcg catcttttca ggaagaacat gctccacata ggcctgatca actgacagac
     5341 ctttctccgt catttgactg ataattgtgt cctcatcctt gtagttgatg ctggctggag
     5401 aggtaatccc tgcttgcaag agcaaggttg ccatcatttc agggctatac tgctctgtat
     5461 aacgtggcac ttcaggtcgt gtaccgacaa aggacatctc acctttaagg acattgacca
     5521 actgaggcag ttcgtccaaa cggacacgtc ggatgaaatt tccaaccttg gtaatgcggc
     5581 tatcgttagc agaagtcacc agacttcctt ttttatccgc atccgtcacc atggtacgaa
     5641 acttccaaat cttgaaccga cggttgtact gggtcacacg ctcttgcttg taaatcactg
     5701 gccctttgct atccaacttg atccaaatgc tcaagatgag aaagatggga gaggtcagaa
     5761 ccagtaagac caaggccaaa acccagtcca agcaacgctt gaaaatcagc gaacccttcc
     5821 ttttagagac aagctggtag taagactcaa cctcgcttga tttcatttcc acaggcaagt
     5881 cttcccattt cagcatgctg ttctcctttg tttttattat actatttgtc aacatttttc
     5941 attataccac aaaatggaaa aggcggtgaa agaaatctgt aatttgaagg atttccttct
     6001 agtactcaat gaaaatcaaa gtacagcttt gagattgcag ataaagctga catggtttaa
     6061 agagattttc aaagagtatc ggccatggcc cctgcctgca aactatacat cttgtgatag
     6121 gttactccca gagccaagag ttcctcatgg gttccactct cgataatgcg tcccttatcc
     6181 aagacataga tgcagttggc atcttgaata gtagaaaggc ggtgagcgat agcaatagtt
     6241 gttcggccct gtctcatctt cgccagagaa gcttgaacca agctttctgt ttcagagtca
     6301 atattggctg tcgcttcatc caaaatcagg attttaggct ggctggcgac tgttctagca
     6361 aaggcaagaa gctggcgttg cccagtagag aagctcgaac cacgctcgga aacaggggag
     6421 tcgtacccct gaggaagttc ttgaataaag gaatctgcat ccacaaaggc tgccgcagcc
     6481 tgaacctgct catcactggt ttcttggtac atggcgatat tggacttaat agttccatga
     6541 tagaggaagg gttcctgcaa gaccaaaccg atgttttttc tcagctcttc ttgactgaaa
     6601 tccctgatat ccacatcatc caagagaact ctccctgact ggaattcata aaagcgcatg
     6661 aggacattga taatagacga tttccctgaa cctgtatgac ctacaaaggc aatggtttca
     6721 cccttattaa cagagaaaga aatgtcatcc agaatcggat gtttaccgtc atatgagaaa
     6781 cacacatgtt caaaacggat attgccttct tggactttgg cttgcccatt ttcttgaaga
     6841 ggttcatagg tcctctcgtc tatcagggca aagacacgac ctgcagaaac catagccgtt
     6901 tgcagagttg aaaagttttg cgtcacctca atcaaggggt caaaaaggcg gttgatgtac
     6961 tggataaagg catacatggt cccgaccgtt atcccgatag aaaaaccacg gtagccaaag
     7021 taggccatca agactgcata gcctagaagt ttcagcaaac tcatggcagg tctcaaaaag
     7081 agggcatcca aggctacaga acggttggcg tagaccaagt gttcttggtt gatttcatca
     7141 aattctgcct gcaggcgctt ctcttgatta aaggcctgaa taatcctgat tccctcgata
     7201 ttctctgcca gcttactatt gatatctgac aagagacttc tggttttctc gatgattttc
     7261 actgactttt ttcgatagag attgaccaaa aggaaaatca aaggaagaaa gagcaagact
     7321 aaagccgtca aacgaaaatc cagcaccaac atggtataaa gggttgtcag aaagataaaa
     7381 actgctgaga taaagctgga taaaatccca gaaaacatat cactaatcgt ctcggtatcg
     7441 ttggtcaaac gagaaacgat agaacctgct ggcgtcttgt caaagtaaga catgcccagt
     7501 ttctccatat tggcaaaggc atcccgacga atatccctaa caatactgta agacacgcgc
     7561 gcaaagagaa gattgcctac atactgaact acagtttgta ggatgtagag accatagtag
     7621 accagcaaaa cggtaacggc tagttggtta agattgctga gatactggtc gataaagtgg
     7681 gaagccacga ggggtatgac acttttaatg accatcgtcg ctaggagaaa actgagtgcc
     7741 aaaaaggtca ggagtccata aggcttgaga taagacatca agcgcttcaa tacagcccat
     7801 tgttcttgtt tattctgcat cttcttctcc tttcatttcc aactgctgag actggtaggt
     7861 ttgggcatac cagccatcca tcgctagcaa gtcttcgtgc gtgcctcgtt cgataatttg
     7921 accattttgt agaactaaaa taaaatctgc atggacaaca gcactgaggc gatgggcagt
     7981 gataatggtt gtcttgtcct ttcgcgtctc cttgaggttg tcgataatcg catactctgt
     8041 cttggcatct acggcggata aggaatcatc caaaatcaag atatcagggt ctaaaatcat
     8101 agcccgactc atagccaacc gttgcttttg accaccagaa agactgactc ctttttcacc
     8161 aatcagcgta tcaaatcctt gaggcatgtc tacaatatct tggtaaactc gggctagctt
     8221 agtagcttcc tcgaccgctg aaaggggcaa gttaggattg ccaaagcgga tattgtctag
     8281 gattgaagtc gcaaagagaa actggtcctg aggaacatag cccatgagac tgcgaaggtc
     8341 tgtcagacga tagtcccgaa tatcgtgacc gtttagataa atagtaccct tatccacatc
     8401 gtattcacgc aagaggagct tgattaagga cgttttccca gagcctgtct gcccaaccaa
     8461 gcccagtgtt tgcccttttg ccaaactaaa gtgaatatcc gtcagtgttt cctcattttc
     8521 aaaagcaaag ctgtcaatgg catactccaa acgcccattt tcaataccat ccagaggaaa
     8581 ctcagggtct tgtacaggag attcctgaga caaaagattt tcaatccgct ggtaagaaac
     8641 cttccctcgc tgagtagtat taaagaggaa accgatggcc agaagaggcc agaccagcat
     8701 atccaaatag ctgataaagg tgactagatt cccaactgta atctgccctt cctgaaccat
     8761 caaggagcca accaaaagcg ttaaaacata ggacgaacca acaaacaaga gaaccatagg
     8821 gtcaaagaga ctatcatatt tcatggtttg caggttcttt tggaaggtta attcattgac
     8881 tgcctgaaaa gacttcaact cgtctgcctg ataaccgaaa gacttggtca ctttgatacc
     8941 tgatacggac tcctgtacct tgttattgag ttcagaaaaa gcagcttggg attcgccaaa
     9001 ggccttatga gtctttctcc ctaggcgact agtcgtatag gccatgaaag gtagggggag
     9061 aatggcaaca agagtcatct gccatgagat gctaaagagc atggtcaaca aagtcaccag
     9121 agccgtgata gaggcatcca ccgcagacat gacaccgcca cctgctaaac gagtcaaggc
     9181 attgatatca ttggttgcgt gtgccatcag atcacccgtc cgataggttt gataaaaggc
     9241 tgacgacatt tttgtgaaat gcttaaacaa gcgagaccgc atgatctgtc ccaagcaata
     9301 agaggtccca aggatataca tacgccacac atagcgcaaa tagtacatac caaaggctgc
     9361 aagtagcaag taaaataggc taagaaggag gtcctgctga gttaattgcc ccgatgtgat
     9421 ggcatcaatg actcgcccca taaccatagg aggaatgaga ttgaggacgg aaaccaagac
     9481 cagggccaca atcccgacta gataacggcg tttttctaac ttgaaaaacc accagagttt
     9541 ttgaataatg gacataaaat ccctttctga ttgcaaatgg aaacctgagg ccaatactca
     9601 atgaaaatca aagagcaaac taggaaacta gccgcaggct gctcaaagca ctgctttgag
     9661 gttgtagata gaactgacga agtcagtaac ctacatacgg caaggcgacg ttgacgcggt
     9721 ttgaagaaat tttcgaagag tacaagaccc caggtttttc ttattcataa gttacgactg
     9781 taacagcacc cttgtcatat tcagcaataa agatattggc tacattgtca tgcccttgtt
     9841 tactgaggtt atcaagcaac cactcttcgc tacgaccaat cgattccaag acatctactt
     9901 gaatcacacc gtctgtcaca actggatact taggattttc atctcccatt tgcacaacga
     9961 tgagttgccc attttgctct tgcacagctc gtttgacttg cttcatctgg aaaatccctt
    10021 ggctacgaag tttgagggct acatccgatg cagacaaacc aactgaacga caggcttatg
    10081 ggtcaatatt cccatttttg ataaggagag ttggcttacc atcaatcaaa cgtttcacaa
    10141 agtgaacatt gttgttgagc tatttgaaag tcaagatcag tttgattaaa atttcgatat
    10201 aattaagtgt catttgttca catccaccag ttcaattgcg tctgtcttat acaattcgac
    10261 tttctctaac aggtacttgt ctggctcact tccgtttagg gcacgataat agcgatctcc
    10321 caccttgata agtgcgccat ctgtgtttgt ggaagtatta acatagactt ctgacttgtc
    10381 tactcccaaa tctttggaaa caacctcgat gaaatgaagt gaagtttgaa atttattgtt
    10441 agaaacttga ttgttttgat aagtcgtgat gctgaccaaa agcagagcta aataaggcca
    10501 gagctgaaat catgaccaac tcacgaaatt tggttccttt tttatcatgg tatgccttga
    10561 aagcaaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat gataccattt
    10621 tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta ttttcactcc
    10681 ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa ccatacgttg
    10741 gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa aggtaacttt
    10801 atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag tgactcagct
    10861 cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc tgatatcatt
    10921 gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt ggaaatttta
    10981 gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc tgcccgtaaa
    11041 ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactgt cactttccca
    11101 gaaatcggtg ccccttctac catggacttg gaaggccgca tcatcactct agaatttgat
    11161 gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa acgcttggaa
    11221 gaacgccaag tctgggatgt taaatatgct gagtatttgg ctgaactaga caaagaaaaa
    11281 ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct tgcaaatcct
    11341 gctagcaacc gccgttcacc tggatttact gacgaagaac gtgctggatt taccaacctt
    11401 ttggcaactg gatttacaga caccttccgc catgttcatg gcgatgttcc tgaacgctac
    11461 acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg gagaatcgac
    11521 tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat gattgactca
    11581 ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg attttctata
    11641 tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa tatcgaacag tcccggtcct
    11701 tctactgtgg tttactgggt tttaggattg aataccaacg tccagaagaa aactttctct
    11761 tgaagagtgt caactaatgt tagaggaggg aacaaaggat caactagctg aactgaccta
    11821 cccctttggt cgtggagtca atctctcctt tggcataaag gatgttccaa aactctatta
    11881 aagagtgatg aaggcaaact atcctattta tcgtcccttg accaaaagaa agtttcgtgt
    11941 cagtgatccc tatatctatc ctcataaatt tgcagttttg gatccagatg gctatttttt
    12001 aagatttagc gagtagaata ataaaaattg ggaaaagtct ttaaagttag aaaaaggcat
    12061 attgtcaggt gtctaaaaac ttgatagtat gccttttatg atggaaaaat cttctaatac
    12121 tcttcgaaaa tctcttcaag ccacgtcaac gtcgccttac cgtaggtata tgatactgac
    12181 tctgtcaatt ctatccacaa cctcaaaaca gtgttttgag gttgtggata gcttcctagt
    12241 ttgctctttg attttcattt agtataaatg ttagcttaca atggagtttt tgttcacccc
    12301 ctcttctgtt tgttcgtttt ttaaatcaaa acactaacaa aatagttgat ttataaagtt
    12361 atttagtgta aaataaaaac attggctcaa gcctatttaa aattgaatat cgttttactt
    12421 gtttatgtcg tgaattggca cgacgtttct acaaggtgcc ggaacaccta acaataagta
    12481 agtcagcagt gagatatggt cgtttttgcc atgcctattt gggggactta cttagagatt
    12541 aagtaggtcc tttttgaata tttttaatat ttcccttaat tagtgcggac gggaggtgaa
    12601 attatcctgt gaataatttc aggaattcag ggaatttcat ccctaatttt tgagccccta
    12661 gctctttcat ttctaggctt aggctaaaat agttccccga actattttac tctcaaaaat
    12721 cccgtcatag acaataacaa gattattgtc tatgatacca ctacatcggg aaatatttga
    12781 taagactatt acgagcgaag cgagtcttat caaatatata gtattagcaa aagggatcac
    12841 tatagaaaca tttcaacaac aagtaaatta gcttttagac tttaggaggt cttatgaaat
    12901 tattagaaga tcgcatcctc aaggatgggc atatcttggg tgataacatc ctcaaggtag
    12961 attccttttt aacccaccaa gttgacttta gcttgatgcg agagattggt aaggtttttg
    13021 cggaaaaatt tgctgctgcc ggcattacca aggtcgtaac cattgaagcg tcgggtattg
    13081 ccccagccgt ttttacagct gaagccttaa acgttcccat gattttcgcc aaaaaagcta
    13141 agaacatcac catgaacgaa ggcatcttaa ctgctcaagt ctactccttt accaagcagg
    13201 tgaccagcac tgtttctatc gctggaaaat tcctctcacc agaggacaag gttttgatta
    13261 tcgacgattt ccttgctaat ggccaagctg ctaaaggctt gattcaaatc atcgaacagg
    13321 ccggtgccac agtccaagct atcggtatcg tgattgagaa atccttccaa gatggtcgtg
    13381 atttgcttga aaaagcaggc taccctgtcc tatcacttgc tcgcttggat cgttttgaaa
    13441 atggtcaggt cgtatttaag gaggcagatc tctaatgcaa actcaagaaa aacactcgca
    13501 agcagccgtt ctgggcttgc agcacttact agccatgtac tcaggatcta tcctggttcc
    13561 catcatgatt gcgacagccc ttggctattc agctgagcag ttgacctacc tgatttctac
    13621 agatatcttc atgtgtgggg tggcaacctt cctccaactc caactcaaca aatactttgg
    13681 gattggactc ccagtcgttc ttggagttgc attccagtcg gtcgctccct tgattatgat
    13741 tgggcaaagc catggtagtg gcgctatgtt tggtgccctt atcgcatctg ggatttacgt
    13801 ggttcttgtt tcaggcatct tctcaaaagt agccaatctc ttcccatcta tcgtaacagg
    13861 atctgttatt accacgattg gtttaacctt gatccctgtc gctattggaa atatgggaaa
    13921 taacgttcca gagccaactg gtcaaagtct cttgcttgca gctattactg ttctgattat
    13981 cctcttgatc aacatcttta ccaaaggatt tatcaagtct atctctattt tgattggtct
    14041 ggttgttgga actgccattg ctgctactat gggcttggtg gacttctctc ctgttgcggt
    14101 agctccactt gtccatgtcc caactccact ctactttggg atgccaacct ttgaaatctc
    14161 atctattgtc atgatgtgta ttatcgcaac ggtgtctatg gttgagtcaa ctggtgttta
    14221 tctagccttg tctgatatca caaaagatcc actcgacagc acgcgccttc gcaacggtta
    14281 ccgcgcagaa ggtttggccg tacttctcgg aggaatcttt aacaccttcc cttacaccgg
    14341 attttcacaa aacgttggtt tggttaaatt gtcaggcatc aaaaaacgcc tgccaatcta
    14401 ctacgcagct ggtttcctgg ttctccttgg actgcttcct aagtttggtg cccttgccca
    14461 aatcattcca agctccgtcc tcggcggtgc catgctggtg atgtttggtt ttgtatctat
    14521 tcaagggatg caaatcctcg cccgagttga ctttgctaac aatgaacaca acttccttat
    14581 cgcagctgtt tcaatcgctg caggtgtcgg tctcaacaac agtaatctct ttgtcagcat
    14641 gccgacagcc ttccaaatgt tcttctcaaa cggaatcgtc gtagccagcc tactcgccat
    14701 tgtcctcaat gccgtattaa atcataaaaa gaaataagaa aaagaggtgc gagcctcttt
    14761 tttgtgtgac aaaataaaaa catctaccta ttcatatatg ctagtgtcat agtcctgaaa
    14821 atcatctgca tcaagaacaa tttcacaact cttatacttt tctcttacaa gtcgttcggc
    14881 ttcatctgga ttttcagcct ctatacttac taaacgtgat aaagtttctg taatttctac
    14941 tgtatacttt ttcagtttta gattgctttc caataattca cctattaaca ataatctatg
    15001 ataggagcta tgtagccact ctggcaattt atctcctact tcccacccat atttttcctt
    15061 catcaaagct agttgttttt cgtcaccaaa tttcatattt tcagataacc atctcacaca
    15121 atcgggatct gataaggtac agacgattaa acttaggtta tcgtaacggc tttcagtttc
    15181 ataatcaggc cagatgactt ttaagaaatc atacacctct tctgatgcaa caagttgttt
    15241 cgttttcata atttccgata ctttcctcta cctttaaatt ctattatttc tttgtctctt
    15301 aatatttgaa gctgttgcct aatcttttct ttgatatgat tgttcttaac aaagatattt
    15361 tttaggtcac tttcaaaacg atacatatct tcaagggtaa attctgaacc ctctatctta
    15421 tctatacaat ttagaatttc tattgtccaa cctcttgatg acagagagct cttccttaaa
    15481 aataaacctt gcttaaattc ttttgtaact ttttctggat ctctaacttg tccatcttgc
    15541 acaagaaata tccttccttt agaaggtact tgtgataaat caatgttaca accaatccaa
    15601 cctgctcgtc tagcagttgg tgcaagtggt tttctttgaa taatcgattt cggtgtaaca
    15661 aattgcttcg gaaggacaag aaagttattt acctcaaaat tttttgtgta agttaaaaaa
    15721 aagaaattag gattattatc tgcctgcaca cgcttcatca tcgttgcata agcaccatca
    15781 ttgattgttg atgaaaaatt tccttttttg ctctttagtt caaactcctc actacaatga
    15841 ttacagtaaa aatctgctac aggccgatta ttttcaaaat gatttaaggg attgttccca
    15901 caattagggc aataagactg acgataaacc caatcctccg ttaagatacg tgccttttgg
    15961 ctattacttt tataggtttc tactaattct aaattaaagt gtaattccat ttaaaaattc
    16021 ctcactaata tgagaactca ctcgatataa gcaattaaaa tctactataa ctagtatacc
    16081 acatatatgt acctattaca tttgtatttc atcactctct tttatatttc cttctaacat
    16141 atctcataaa ttaaaaatga gtgagataaa tttatcccac tcacctttct ttatatactt
    16201 acccgtcttt cctcagacct ttggcctgtg acaaacatgg taaaggttgc tttacagaca
    16261 tttctgccct cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg
    16321 acacattctc ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata
    16381 gaggattgga gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg
    16441 tcacatagcg tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc
    16501 actactttgg tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca
    16561 aaggcagata tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaacga
    16621 cactatgata ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt
    16681 ccgacatgtt ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact
    16741 cctgcatcct caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg
    16801 gctttttctt tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga
    16861 tgataatcgg caactgtaac agcttctcct acaagatagc tcgcgacttg ctccacttct
    16921 tctttcagac gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc
    16981 ttcttgatat gttggacatc cttgtgggga tgatagatgc catcaggatg ctctgctgaa
    17041 gtctgattgt ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt
    17101 ggtgtgatgg tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct
    17161 gaatactgac gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa
    17221 tccgaagtca agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca
    17281 aaaccagcaa atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg
    17341 cctccctgat aatgatcgtg agttagaata gagcccccca caatcggcag gtcggcatta
    17401 gatccagcaa aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga
    17461 cgactaatgg ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa
    17521 gcatagggcg aatactggaa cccccattcc tgaccaacca tttcaaaacg gataatccgg
    17581 tggttgctgc gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt
    17641 tgacactgag gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc
    17701 ttttcaggct tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga
    17761 taagcgatat ttttagcaat ggccttgagt ttgatgtaat catttttctg actgagttga
    17821 taaaaatcct ctatcgcttg ctcaggagag tggacatagg cttcccagaa gtcacgattg
    17881 acctgactcg gataaggagt caccaagtcc atcagttcag taccaaggat ttcacgcgca
    17941 gtctgactat cctcaatcat ctctaatcga acggcttcct caactagctg gtccttgagg
    18001 tcaatcaatt tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa
    18061 acacggttgg tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt
    18121 gttacaaatt tatctactaa gatcactata gagcctcctt ttgactagtc aaggacgcga
    18181 gtgccacctg caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag
    18241 tgtttgccta cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca
    18301 cagccaccaa aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct
    18361 gtgtgaacaa gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg
    18421 tgtgacgcat tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga
    18481 gctttaaggg tacgttggtt ttcaagcaca gcatggcgag cacatttcaa acgattttca
    18541 tctttaatca aatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga
    18601 atatccaagg caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg
    18661 tatttagagt ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc
    18721 ttcaaatcaa gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt
    18781 tggtcagccc ccataccaat agcaaactgg tccatgatac cagagttgac tccgataaag
    18841 ttgttttctg tttgttttcc gattttaacc aaatccaaac ggtctagttt taaatcaaag
    18901 agatgctctg ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca
    18961 ccatttggga tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct
    19021 tcttgcaaga aatgaagaac cccttttgga taattggtcc agttgtgctc tttttcaaac
    19081 ttgaggtcag cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa
    19141 cgcaagactt ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca
    19201 ggaaaaacgt gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat acggcctggt
    19261 gaaaagaagg tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaaggact
    19321 tcagtagtaa gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccatcttaa
    19381 cgtgtaatcg ttttctttct attgtatcca aggaatttcc caaggtcaat cctttttact
    19441 aaaattttac taaaatatca gtaaaaagaa gaaaaatatg atatactaac ctaatcaagg
    19501 aggatttatg gctaccttaa aagacattgc acagctagcc tctgtctcaa tcgcgaccgt
    19561 atcccgtgtc ctcaaccgcg accagagcct atctgttaca gaagaaacca gacaccgtat
    19621 tttaaccgtt gctgaagagc taggctacac caaacacctc aagacaggcg agtcccacaa
    19681 gcccaagcaa aagattgcca ttatccaatg ggtcagcgaa caaggggagc tagacgacct
    19741 ctactactac cagattcgcc taggaataga aaaaagagcc caagagttgg actacgatat
    19801 cttgcgctat tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg
    19861 catcggaaaa tttagccgag ctcagatttc tgcctttgaa gaataccaaa agcctcttgt
    19921 atttctagac agcgatacac tttccctggg acatacctgt attatcacgg atttttacac
    19981 tgctatgaaa caggttgtcg attatttcct cagtcaaggg atggaccgca tcgggattct
    20041 aacagggctt gaggaaacaa cagaccaaga agaaatcatt caggacaagc gtctagaaaa
    20101 cttcaaaaac tacagtcaag cgaggggaat ctatcatgat gaactggtct ttcaaggaag
    20161 atttactgcc cagtctggct atgacttaat gaaggaggcc attcagagct tgggagacca
    20221 acttccgcca gcatttttcg cagccagcga tagtttagct atcggtgctc tccgtgccct
    20281 ccaagaagct ggaatcagcc tgccagatcg cgtcagcctc atttcattca acgacaccag
    20341 tctgaccaaa caggtctatc ctcccctctc tagtattaca gtttatactg aagaaatggg
    20401 gcgagcaggt atggatattc ttaacaagga agtcctccac ggtcgcaaaa ttcctagcct
    20461 gaccatgctg ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa
    20521 cataaaaaac gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag
    20581 acttaatggt cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat
    20641 aacttgaagt aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa
    20701 attgcttatc gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa
    20761 atgtcgaacc aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc
    20821 cattatgaag aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg
    20881 ctgcgtctgc tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt
    20941 ctgcaacaac agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc
    21001 tcataaggat aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa
    21061 cagccccatc accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg
    21121 catgatagcc tgtcggcatg acatctgcaa gagtcaaaag ggacttgagc atcccttctg
    21181 tatagtcaga aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa
    21241 tatattctgc ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt
    21301 caaatccagc aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa
    21361 aatcacctgg tttcaccgtc gtaatggctt ccccagcttc ttcaacaatc ccaatcgctt
    21421 cgtgtccact atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg
    21481 aaccacaaac gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg
    21541 gacgttcaat gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt
    21601 aaaattttcc ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta
    21661 gctgagacaa gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct
    21721 ctctcgtttc atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga
    21781 cacccgccga acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat
    21841 cacgaatccc agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc
    21901 gaatcgtatc cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac
    21961 ctcctctcat ttcattcact gaattcacgc tattctaact cacttatctt attatataac
    22021 tttgagttga ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa
    22081 tcatatatct ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa
    22141 taaagaaatt actctattcc aaataagata gtacccaagt atttttcact tttttctaat
    22201 gttgatgctc ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt
    22261 ctaggtcagc atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc
    22321 gaatagactc tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg
    22381 catttttttc caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt
    22441 ccaatcgctc caggccactc tttacttgct tgatatcaag accttctggc acagcatcca
    22501 agaaaatctt gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa
    22561 tgacaaggga caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca
    22621 tcaggataac agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact
    22681 cattctttgt ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa
    22741 taattcctaa ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga
    22801 cattttccaa aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc
    22861 ctagcaggct aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga
    22921 ttgtttctag aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt
    22981 cagcaagaac agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag
    23041 tcaaatttaa gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt
    23101 tgttataata gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa
    23161 ggatagaagc aaaacgtcag ctttattcag ttctgaacaa tttgcctcaa gtgtccatat
    23221 gactaacatt gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca
    23281 acttttgaat gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga
    23341 tgtgggacga tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct
    23401 ctgccgctac ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta
    23461 cctcgcccac ctctttctgc attttcataa aaaccaagac catatcacca gtctgctatt
    23521 ttccaaaaat gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc
    23581 cgtgctagct gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca
    23641 cttggtcatg tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt
    23701 cacagaccag gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata
    23761 gagtaaagct cagttgtctt atttctagat tactgagttt tttatctttt caacaacaaa
    23821 agaggacccg ccgatcctct ttttcatact ataaatcctt gattatcaac tatatctgtt
    23881 ttaatcgaaa tctcaaaaca gcactttcaa acatcttttc ctagttaagt aaatcagtat
    23941 tctgcttagc tgccttgctc cattgatacc aaccaactag actgttaatg agataaatta
    24001 gatatttccc ttgaatttgc aggctttctc cccaccagag atagattgaa aagacattgg
    24061 tagccgccca gaatatccac tgttcacggt aaacagctgt catgaggatt tgccctaccc
    24121 cattggttgc atctgtgatt gaatcacgat agggacgatt ggcaccaata gactgataaa
    24181 tgaagccaaa ggccaaccac caaagcacac taatggaaag atactttgtc cagcccttgc
    24241 cgtccagttt acgcgcgaca aactcctgct tttccttctt aaactgtgcc tgataaatcc
    24301 aaactagaag tccaattggc tgcatgactg tgaagtaaag tgtcgtcagc acctcaccat
    24361 aaaagccttt ctgtagggcc aaaataaggt aaataacaga gttaatcaag ccaaaaagat
    24421 aattacttgc tcgaccttcc gatacaaaga ttacacagat aatccctgtc aagctacaaa
    24481 tcatcccaat ccagtcaaca atacgatgtt cgtaaaccaa ctccagccag agaggaaaac
    24541 ttcctaaaac cagcaaataa atccactggg caaaactacg atgggcaaag aggtcatccc
    24601 agatagcctt catagttcct gaaaatccta aatcagccat agccgcaacc atacgacggt
    24661 aaccacctga catttcacct agggttgttt tgatattttc aattttcttt tgcaaataag
    24721 tatgcatcat ttctcctttt gtttttaaag agccgtgtct ggatagactt tcggacgcaa
    24781 cgctctatta gataatgaac tgcctataca caagatttct aaccttagtc gacatgagct
    24841 gaaacctctt atttgttaag tagttcacaa aatattatac acctatttta tgaatagtca
    24901 actgtcttta cagtaaaatt ttagaaaatc atgaaaattt tctctttctt tccattttaa
    24961 gtgacattca gtcattctca catcaaaaaa gcccagacga aattgtctga gcattctttt
    25021 atctagtcgt ttaaggaagt tgagttcagt atgtttaaag tctctgtccc atcatttctt
    25081 caacaaacct tgttcttgga gaaactcctt ggctacttgc tctgctgact tgccttcaac
    25141 accgacttgg tagttgagct ggctcatctg gttttctgta atcttaccag ccaatgtatt
    25201 aagaactctt tccaactctg gatgtttctt gagaagagct tctttcatga gtggagcccc
    25261 ttgataaggt gggaagagtt gcttgtcatc ttccaagacc tgtaaatcat aacgctccaa
    25321 ttccgcatca gtcgaatagg catccgtgat ttgaatatcc cctgactgaa ttgcctgata
    25381 acgaagagct ggctgcatag tcgccacatt gagattgaga ccatacattg attgcaagcc
    25441 cttatttcca tcttcacggt cgttaaactc aagcgtaaag cctgccttca gctgcccttc
    25501 cacttttttc aaatccgaaa tggtcttcaa gccatattct tgagcaatct ttttcggaac
    25561 agctacagca taggtatttt gataagacat aggtttgaga taggctagat gatcctgctt
    25621 ggcaatgcca tcacgcgcca cttgataaac ctgctctggc tcatgactca ccttgggtga
    25681 tggttgaagc aaactttcag tcaccgtacc ggtaaattca ggataaatgt caatatcacc
    25741 ttttttcaga gcttcataaa ggaaacttgt cgtcccaaaa ttcggtttaa cagtcgcagt
    25801 catgctggta ttttcttcaa tcagcaattt atacatatta gccaaaattt ctggttctgg
    25861 gcctattttc ccagcaataa tcaagttttc cttctctttt tgagccaaaa gggctggact
    25921 ataagacaga cccagtaata aagccaccaa ggcaaaacca gagaaaatcg tccgcaattt
    25981 cgctttttcc attactttta gtaggaagtt aaaggcaata gctagcactg cagaagaaag
    26041 tgccccaatc aaaatcagac tggcattatt acggtcaatt cccaaaagga taaaggaacc
    26101 tagtccccct gccccaatca aggtcgccaa ggtagccgta ccgataatca agaccgctgc
    26161 cgtccgaatt ccagacatga taacaggcat ggcaagtgga atttcaaact tcttgagacg
    26221 ctcccatctg gtcatcccaa aggcaatccc agcctcttgc agactcggat caattccatt
    26281 cagcccagta atagtatttt gtaaaatcgg aaaaatcgca taaatcacta gagctgtcaa
    26341 tgccggtaaa gtcccaattc ccatcaaagg gataaagagc cccaacaagg ccagagacgg
    26401 gatggtctgg aaaatacctg caatctgcaa gacccagtcg gccagcttct catgatagcg
    26461 aagataaaca gccaagggaa tcgcaagcaa aatagctagt aacaaggtca aaagtgacaa
    26521 ctgcaaatgt tgagataggg ctgtcaacca atcaccaaaa cgatcctgaa aagttgcaat
    26581 taaattagtc atgaatacta cctccaaaca agtctgcaac aaagtctgtt gcaggagctt
    26641 ttaaaatagt ctcaggattc gacacctgac gaatctctcc atcctgcaag acagcaatac
    26701 gatctgccaa ctttaaggct tcatccgtat catgagtcac aaaaatcgtt gtcatcccaa
    26761 actctttatg taattctttt gtcagaacct gcaactgttt tctcgaaata gcatccaagg
    26821 ctgaaaaggg ttcatccatg aggagaatct tgggctgacc aatcatagct cggacaatac
    26881 cgacccgttg ctgttctcca ccagatagct cacttggaag tcgatgccca tactcagcta
    26941 ctggtaaacc aaccttagcc aaaagctctt ctgttttttg agcaatttct tccttagtcc
    27001 aacccttcat ttcaggaatg agagcaatat tttcctcaac tgttagattg ggaaagagag
    27061 caatagcctg taaaacatat ccagtagaaa gacgaagttc acgctcatca tagtctttga
    27121 tgcgcttccc atccatataa atatttccat cagttggttc caaaagacgg ttaatcatct
    27181 tgagcatggt cgtcttacct gacccagaag gccctactaa aaccataaat tccccatcct
    27241 caatctgtaa gttgacatct ctcaagacat ccttttctgt gtagcgcagt gctacatttt
    27301 tgtattcaat cattctttgt cctcaattta aaacttccct cgattagtca agtcttctac
    27361 cttaggcatg acttccttat tatcccaatg ctccacaatt ttcccgttct ctaaacggaa
    27421 gatatcgtac tgggcataag caacgccatc aatctgagtc tgaccatagc taaccacata
    27481 gtttccttgt cctaagagtt ggaaaacaaa gtcaaaagtg acactatatt cagccacata
    27541 gtttttataa gcagcacttc cttgtccaat ctcatgatta tgctgaatca aatcgtctgc
    27601 cacataatca ctccactgct ctagctcccc attttggaaa atttctgtca agaaacggcg
    27661 aaccagcttt ttattttctg ctttcttatc caaatccttg atttcaaaat ctccaaaaat
    27721 ttgatctagt tggtcatttt caggtgttcg atagtagtca atgacatccc aatgctcaac
    27781 aatacgacca ttctcatccg cacgaaaagt atccgtcgtc acccattgag cttctccacc
    27841 attcagatat tgatgaacat gaacaaagac cagattgcca tcctcaatgg tgcggacaat
    27901 cttaatctga cgctctggat gacgctcaaa gaaatctgca aagaaggctg caaatccttc
    27961 tttcccgtca ggaacacctg tcgaatgttg gatataggta tcccctacag actgggcttg
    28021 agcctcagca actcgtccgt cttgaatggc atggatgtat aggttgtgag catttttcac
    28081 ttgttgtgac atattctaaa cctcatttcc cttctctttc aaattcgcca aaattctttc
    28141 ttgaaaacct tcaaattggt gaatttcttc ctctgaaaat cctttgtaaa agatagtatc
    28201 caatttctga ctgacacgat gccccacttc tttctgggac ttgcctaact ccgttaaaac
    28261 taaatacttc ttacgcttgt cttttccaca cggactaaca attacaagct tttgttcctc
    28321 tagctttttt atcatagtcg tcagcgtatt attcgcaagc ccagtcgcaa gcgcgatatc
    28381 tgtcgcagtt gcgcagccag tttcactatt ccataaaacc gctaaaatct tgccctgttc
    28441 acccctataa agagcctcag gatcttgact cagtaacttt tgaaaaatcc gcccattcaa
    28501 caaacgaata tgatgggcta gcaaatgacc atctttcata acacctccaa tttatttcga
    28561 tatcgaaatg aataaaacaa ttgtaacact catcgttcta actgtcaact atttcgattt
    28621 agaaataatt tttgataatt atccacacca ccatactccg gctcaactaa cttttaacga
    28681 gagtttctaa actccttcgt cctccagtct acaaaagcct tccattcgta ctatcctata
    28741 ttttatgagg ggacacattt ttcctatcag accatttatt ttaaagatag aagtaaatca
    28801 taattgcttc catctgttct tttatagtat attgaagtta gactagagca ctgtatcttc
    28861 taaaacattg atagaaagcg atttgaattt cccaatcaat ttgttcgtat ttatagcatt
    28921 tcgaaactgg aataggacac catgactgct aaaagatttc tataaattca tttgattttc
    28981 ctaatcaatt tgttcatatc ttatttcatt ccgctataat ttcaccttac cctatctttt
    29041 tcgtagcacc cttcaaacag cctatcccct accgtttgac gattcctcac ttcgctccac
    29101 ttccattaca gaagtttctt cactactatg ggctcggctg acttctcatg attccttgtt
    29161 actactattt gaacgctcac gagatagatc ttacaaaaaa tgctttgatc cacaatggaa
    29221 tcaaagcatt ttaaagagtt cctcatacat aagcgcagaa gtcgcagttc ctctgtactt
    29281 ggcttcttct cttttgataa agcgagccaa gttgagcaac tcaggtgctg gatgtttggg
    29341 atttaggagc aattcacgat tgaccaggcc tgagagacga actgcctgca attgttcatt
    29401 tgtagtaggc agttttttag cagtctctag gagagcagca actaaatctt cactcaaatc
    29461 atgtcgagca tgattgtaaa gatcttttat aaggctttct aggtttggtt ctgccatccc
    29521 taccacctcc cttatggttt aataatgttt aatcaaatca accgttgaac gatccaattt
    29581 cttcaccaag gcttgtaaga aagcttgcgc ttctaggaag tcatccattg catagagggt
    29641 ttggtgagaa tggatataac gagcgcagac accgatagtt gttgatggga caccaccatt
    29701 tttcagatga gctgcacctg catctgttcc gcctttacca cagtagtatt ggtacttgat
    29761 accagcttct tcagccgttg tcaaaagaaa atccttcatc cctgggagaa gcaagtgacc
    29821 tggatcatag aaacgaatca aggttccatc tccaattttg ccttgaccac cgtagacatc
    29881 acctgctggt gagcaatcaa ctgcgaggaa gacttctggg tcaaacttgg ttgtagaggt
    29941 atgagcgcca cgcagaccaa cttcttcttg gacgttagaa cccagataga gttcattgcc
    30001 gagtttttga cctgataaag cttcagctag ctcgcttacc atgaggacac cgtagcggtt
    30061 atcccaagct tttgagatga tatttttttc attggctgtc aaaattgcag aactatctgg
    30121 tacgatggta tcaccaggac ggatgccaaa actttctgcc tcagccttgt ccgcaaaacc
    30181 accatcaaaa acgatatcgg caatggctgg catggttggt cccccctttc cacgagtcaa
    30241 atgcggagga acagaacctg aaatcacagg aatttcatga ccatcacgag tcaagagttt
    30301 gaaacgttgg ctgctaacca ccatggggtt ccagccaccg atttctacga cacggaaggt
    30361 accatctggc ttgatttcgc tgaccataaa accaacttcg tccatatgag aagcgaccaa
    30421 gacgcgcggt gcatccacag cttctgaatg tttgatacca aaaataccac ccaagccatc
    30481 tgtcaccact tcatccacat acggtgtcaa cttttcacga agataagcac ggacaggcgc
    30541 ttcatgacct gagactgcag caagttctgt tacttcttta atttttgaaa ataatgttgt
    30601 catttcagtt ccttctttct ttcatccatt ttaccacttt ttataggaga aggatagtgg
    30661 gaaggtggat ttctaagtta gtatcttagt cctgctctat cttagaaaag gatagtattc
    30721 tcttgcatgt agtgcaaaat ctagtaaaca ttccaaaatt aactcgaata tttatttcca
    30781 aacaaaaaaa caatacacca tcaaagttgt ttagattttt catgaaattt acagaaaata
    30841 gttgacttcc ctttcttctt tctttaaata tatagttggt tgagtttgga atagtacgct
    30901 gtagctgcta aaacatttct agaaattaat ttgactttcc taatagagtt gttcatatct
    30961 tatttcaatt tactatagta caaaactaga aaaggaaaaa atcatgacca aaacaattct
    31021 tgttacaggt gggactagct acattagctc ccataccgtt aaagctcttt taaatgctgg
    31081 ctatcaggtg catgtcctcg ataatctctc cacaggaaat cgagcggctg tggatagtcg
    31141 tgctagcttt aaagaactgg atgtttatga tgctagcgcc ttaaaggctt acttagaaga
    31201 aaatcagatt gatgctgtcc tccattgtgc aggtgaaatt gttgtgagcg aaagtattga
    31261 aaatccaagt aaatacttca ctgccaacgt tgctggtatg aaccaagttc tcaaagtctt
    31321 atctgaagtt ggcattcaaa aaatcatgtt ctcttcgact gcttctctct atggaaataa
    31381 ctgtattgac aagccggtga ctgaagatac cctgctcgac cctgtcaacc cttatgcaga
    31441 gacaaaactg atgggcgaac gaatgattta ctggatggcc aatcgctacg actggaaata
    31501 tgttattttc cgttacttta atgctgctgg ggctgaaatg gatgcttcaa acggtctgcg
    31561 tgtgaaaaat ccaactcaca tcattccaaa tatcaacaag accgcattgg gacaaaatga
    31621 tagcttaaaa atatttggag atgactacga tacacgtgac ggttcatgta ttcgagatta
    31681 catttatgtc ttggaccttg cataggctca tgttaaagga atgaactacc tatttcaaga
    31741 agacagttct tctcaaatct ttaacttagg aactaaaaaa ggctatacta tcaaagaaat
    31801 ctttaaaact gctgaagaat tactaaatta aaaaatccca cacgagattg ttgctcgacg
    31861 tgctagtgac ccagccagtg tcctagcaga tgcttcaaaa gctaaacaat atcttgattg
    31921 gacggctagc tactccctcg aagatattat tttatcagat taaggtaaaa acattttaga
    31981 ataggataac aaaggagaaa gtcttgttgc tctctccttg ttgtatttat taaattatca
    32041 gaaattttat tgacagatta gaaaaataat gttacattta tatccgcaga tatctttcga
    32101 taccaaatct acatgaaagg acggggtatg aaactttctc attatttaat tggcttactt
    32161 ctactcctag tctttctctc tattagcatt gggaccagtg atttttcatg gggaaagcta
    32221 tttgatttcg accagcagac ctggctcctc tttcaagagt cccgtctccc aagaactatc
    32281 agtattctcc tgactgcctc tagtatgagt atggcaggcc ttctcatgca gactattacc
    32341 caaaatcagt ttgctgcacc gagtacagtt ggaacgactg aagccgccaa actgggaatg
    32401 gtgctgagcc tttttgtctt tccatcggct agtctgaccc aaaagatgct cttcgctttt
    32461 gtttcatcca tcgtattcac cctcttcttc ctagccttta tgaccatttt tactgtaaag
    32521 gaaaggtgga tgttgcctct gattgggatc atctatagcg ggattatcgg ctcagtcaca
    32581 gaagttatcg cctatcgttt caatctggtt cagagtatga ctgcctggac ccagggctcc
    32641 ttctccatga ttcagaccca tcagtatgag tggctcttct taggcctcat catcctgata
    32701 accgtttgga aattatccca aaccttcacc atcatgaatc tggggaaaga aaccagcgag
    32761 agtttgggga tttcctactc cctacttgaa aaactggccc tctttctggt ggcgctaacg
    32821 acaagcgtca ccatgattac cgtgggtggc ttaccatttc tcggagttat cgttcccaat
    32881 cttgttcgca agcgctatgg agataatcta agtcaaacca aactcatggt cgcactggtt
    32941 ggtgccaatc tagttctggc ttgcgatatc ctatcccgag ttctgattag gccctatgag
    33001 ttgtctgtca gtctcttgct aggaatcatc ggtagtctcg tctttatcct acttctctgg
    33061 agagggggac gaaaagatgc agactaaaag caaacatacc aagctcttct ggattctcat
    33121 tattcttgcc atcggagctt gtcttctcta cttttggccc atcactcact tgtcagcctt
    33181 tgcttggaag ttgcgttccc aaaagatcat cgtttatctc ttggtagcca tcgcgactgg
    33241 gatttcgacc attagttttc aaaccctgac ggaaaatcgc ttcctgacgc ctagtatttt
    33301 gggaattgaa tccttctacg tcctactaca aaccctacta ctggtttttg aaagcaagtt
    33361 tcttcaactt ggcaaatccc ctatcttaga attcctagtc ttacttcttg tccagtcctt
    33421 cttctttctc gccttacaag gttacttgaa gacactgatg aagcaagacc tggtcttcat
    33481 cctgctgatc tgtctagcgc tcagaagtct ctttcgaaat atcagcacct tccttcaagt
    33541 cctaatggat ccaaacgaat acgataaact gcaaaatagt ctttttgcct cctttcaaca
    33601 tcttaacact tccatcctag ccatcggttc tctgatcatc ctcgctttga caatcttttt
    33661 ctttcgaaaa gcagtcgttc tagatgtctt gcacctgcaa agagaaacgg ctcagatatt
    33721 gggactcgat gttgaaaaag aacagaaaga gctcctctgg ggaatcgtgc ttttgacctc
    33781 aacggccact gccttggtag gacctatggc cttcttcggc tttatgctgg ccaacctcac
    33841 ctacctgatt gtcaaagact atcagcacaa gttactcttt atagtggcca ttctggttgg
    33901 atttattagc ttaaccttgg ggcaagtctt gattgaacga gtctttgcac tggaaattcg
    33961 tatcagtatg atcattgaga gtgtgggtgg cttcttattc tttatcttac tatataggag
    34021 gtctcgtcag tgaaactgga aaacattgac aaatccattc aaaaacagga tattttgcaa
    34081 ggcatttcgc ttgaagtcag tcctcaaaaa ctgacagcct ttattggtcc aaatggtgct
    34141 ggaaaatcga ctctcctctc catcatgagc agactaacca agaaagatca gggagttctc
    34201 agtatcaaag gacgtgaaat cgagagctgg aattcgcaag aactggctca agaactaacc
    34261 atcctaaaac agaaaatcaa ttaccaagcc aaattgactg ttgaagaact ggtcagtttt
    34321 ggacgttttc cctacagccg aggtcgactt agatcagaag actgggaaaa aatccgagaa
    34381 actctgaact atttggaact gaccaactta aaagaccgct acatcaatag cctgtcaggg
    34441 gggcaactcc agcgcgtctt tatcgctatg gtactggccc aggatacgga ctttatcttg
    34501 ctggacgaac cactcaacaa tctcgatatc aagcaaagcg tcagcatgat gcagattctt
    34561 cgacgactgg tggaggaact cggcaagacc attatcatcg tcctccacga tatcaacatg
    34621 gccagtcagt atgcagatga aattgtcgcc ttcaaggacg gccaggtctt tagcaaggga
    34681 agaaccgatc aaatcatgca ggctgacctg ctcagtcaac tttatgagat tcccatcacg
    34741 ctagctgata tcaataacaa aaagatctgt atctatagct agtaacataa aagctcaagt
    34801 tagagaacct tcagtctctt agtcaataag attaagagac tccctaaatc gttatcacat
    34861 tttaaaaagg agaaattatg aaaacatccc ttaaacttta tttcactgcc ctagtggcca
    34921 gcttcttgct cctacttggt gcatgtagta caaactcaag cactagtcag acagagacca
    34981 gtagctctgc tccaacagag gtaaccatta aaagttcact ggacgaggtc aaactttcca
    35041 aagttcctga aaagattgtg acctttgacc tcggcgctgc ggatactatt cgcgctttag
    35101 gatttgaaaa aaatatcgtc ggaatgccta caaaaactgt tccgacttat ctaaaagacc
    35161 tagtgggaac tgtcaaaaat gttggttcta tgaaagaacc tgatttagaa gctatcgccg
    35221 cccttgagcc tgatttgatt atcgcttcac cacgtacaca aaaattcgta gacaaattca
    35281 aagaaatcgc cccaaccgtt ctcttccaag caagcaagga cgactactgg acttctacca
    35341 aggctaatat cgaatcctta gcaagtgcct tcggcgaaac tggtacacag aaagccaagg
    35401 aagaattggc caagctagac aagagcatcc aagaagtcgc tactaaaaat gaaagctctg
    35461 acaaaaaagc ccttgcgatc ctccttaatg aaggaaaaat ggcagccttt ggtgccaaat
    35521 ctcgtttctc tttcttgtac caaaccttga aattcaaacc aactgataca aaatttgaag
    35581 actcacgcca cggacaagaa gtcagctttg aaagtgtcaa agaaatcaac cctgacatcc
    35641 tctttgtcat caaccgtacc cttgccatcg gtggggacaa ctctagcaac gacggtgtcc
    35701 tagaaaatgc ccttatcgct gaaacacctg ctgctaaaaa tggtaagatt atccaactaa
    35761 caccagacct ctggtatcta agcggaggcg gacttgaatc aacaaaactc atgattgaag
    35821 acatacaaaa agctttgaaa taagccactt caaactcaat ttaatactca atgaaaatca
    35881 aagagcaaac tagaaaacta gccgcaggtt gctcaaaaca ctgttttgag gttgcagatg
    35941 aaagctgacg cggtttgaag agattttcga agagtataaa attttgacat tctaaaacgc
    36001 atcctatcaa gttcactcaa acctgatagg atgcgttttt atcattttga aatctattta
    36061 ccccacctca ttccccttct tgatttcgtt taagggaaaa gcggtctgga acggggtcct
    36121 tacctgtttt cgaccaggga tgacaacgta aaatccgagc caagcccatc aataccccct
    36181 taaaaccatg tttttcaata gcctgaatca tgtagttgga acaagtcagc tcaaagcgac
    36241 aagagggtgg aaagactggt gagataaaac gttggtaaaa gcgcacaggc gctattaaaa
    36301 ttcgtttcat tatttcttag ttacagccat ggtgtgtagt tggctgattt cttttttatt
    36361 aagacgacgg gattctcctg gacggagtcc tgtcaagtct aggtgtccga aacgagtccg
    36421 agacaactta tctacttgga gaccaacagc ttcaaacatc tttttaacct gatggttacg
    36481 cccttcatgg atggtcaact gcaccacaga gcgatttttg actgggtcca ctttgagaat
    36541 ttcataaaca gctggcttgg ttttcttacc atcaatctca agaccacggg tcaaggggcg
    36601 gagattgtcc ttattgacca cacctttaac acgcgcgaca taaaccttgt caatctcatt
    36661 acgagggtga atcatctcgt ctgtaaagtc cccatcattg gtcaaaatca agacacctga
    36721 tgtatcccag tccaaacgac ccacagggta aatacgctct ttgacattgg gcaagaggtc
    36781 gacaaccgtc ttgcgaccct tatcatctgt cacactggaa atcacaccgc gtggtttgtt
    36841 aagcagatag tagacctttt cttcgttgta gataggttga ccttcaactt cgaccttgtc
    36901 gcctgacttg atagtggttg ctagttcacg caccacttgg ccgttaaccg tcaccaagcc
    36961 ttgcttaatc agctcttctg cttttctcct actggccaca cctgcgtggg caatatactt
    37021 attgattctc atcttcttct atcctttcac caaataattg gctttcttgg gcttgaatct
    37081 caagctcatc aatcactggt aattcttcta aatggtttat ccccatgtaa tctaggaaat
    37141 aatccgtagt cacatagagg ttggggcgcc ccaatacttc ctttttcccg tcttccttta
    37201 tcaggtcaaa agcctgcaac tttgccaagg ctccactcga gttaactcca cggatggcat
    37261 caatttctat ccgcgtaatc ggctgtttgt aggcaataat ggacaaggtc tcaagggcag
    37321 cccgagacaa gctctggttg ataggcgcct tagagtattc cttcaaaatc tctgcaaatt
    37381 gaggcttggt caccaatcta taagcaccac ttgtctcaat caaagccaaa ctggaatctg
    37441 ggtccttttc atacttctgg gctaattttc ctaaactttg ctggatgcct gtcggtggca
    37501 gagagaggag ttcagctaac tggcggaccc gaatcccatc ttcacccgct acaaacaaga
    37561 gcgcttctat ttttgctaaa gtactcatct ttcctctcta tcaagtctag ctttgaggca
    37621 cttgactttc ttccttcttt tccatgagat agatatctcc gaaactctcc tcttgcacga
    37681 ggatcagctc ctgggttttg attaactcta gggttgccaa aaagagggtg atgacctctt
    37741 ggacattctg ggcttccttg aacaaatcct gcaagcgcaa ttgatctcgt ccaatcaagg
    37801 actctttcac gataatcatc atgtcctcaa tcttatactc atcccgcaag atcgtcgtgt
    37861 gattttgtgc aaactcctct tttttcttgg ctaggatatt tgaaaaagcc aaaaagaggt
    37921 caatggtcgt cttgtcatgc acaagctccg catcttcgta aatcaactct gtcggcgctt
    37981 tggaataata ctgggcccgt tcttggtgct tggcttccaa gtgctcaccc aagagcttga
    38041 acttgcgata ttcttcgatt tgagagagga ggtcctgctc caggtcatcc cccaagtctg
    38101 tcacttctgc taccttcgga aggagtttac gactcttaat cagcatgagc tgactagcca
    38161 tgaccatgta ctcacccgtc acttccagac gcatggcctg cagggttgag acataggcta
    38221 gatactgttc gatgacttcc gtaatgggca catcgtagat atccatctgg tacttagaaa
    38281 ccagatgcaa gagcaagtcc aggggtcctt caaaatcttt taatttaata tccattatct
    38341 atatttttct aaggtcagga ctgtttttaa tcctaatttt tttgcaattt cgtacaaatc
    38401 gaccttgttt tctatttgtc ttagaataaa ctgttcacgt aagacttgag ctgataagga
    38461 tggaaaacct ttctccttga caaaagattc taactgacga aaggcccact gacgagaata
    38521 gggtttctct cctctttcaa aaagataggt ctgccccatc aagggttcca attctgaaag
    38581 caaggccgtg ggaatggtga caatcctctg ttgggaagcc ttgctgattc gcaacacctg
    38641 aaaatccaga ttgatgtccg caaccttgat ggctaaaatc tcactgggca aaagccccat
    38701 ttctaggatt aagagcgcta gcaagcggcc ctctggatgg tcgctttcct gccaaaaaga
    38761 gtctaggtat agaatctctg gcttttccgt cttcttttca gcttgtttgg ctaattccaa
    38821 gcggtaaaag ctgtccacct ctcctttttg atagagaaag tatagaaatt ggttacaggc
    38881 cgaaatcttt cgcttctggg cgctgatttt tagattggct agctgggctt ggtaaatctt
    38941 gagactggtc tcagaaatcc gctcacctac catgtctaaa aattgctcca aatcatactt
    39001 ataggactgc ttggaattga cagacaagcc ctgcttttcc tctaaaaagg ctgaaatcct
    39061 gtctctcatt ggcatcgaat ctcatattcc ttactaaagt catgcaagag ggcattaacg
    39121 gccttgagga tggacttgcg cgtaataatc ccttggaaaa taccctctgc atccacaacc
    39181 ggtaagaagg actcatctac tagcttgtgc aagacctccg taatggtgaa atcaggcgaa
    39241 acaaccgcta cgtccgtttt tgtcatatga acgatatccg tatccgccat gatttcttgg
    39301 ctcaagtcat gctccatctg ataggccata atatctctga gtccaatcgt cccaacaaac
    39361 tgtttttcat ctgtcacaac gggaacacgg gtataggtca tctgactgag caagagggtc
    39421 gcatgatccg cattgtgggt atcaatcaac acagctagat ttttagcagg ggtcaaaaaa
    39481 gtttcctcct gccccaacaa gaaagtctca aactccttgg caatcatcgg ctaaactcct
    39541 tggacaaacc tggatacacc tcgtgatctc gtgtcaaaaa gtccactttg aagtaactat
    39601 catcaatctc cacacgagca tagagacatt ctctgatggt acctcgtggt tggctgatag
    39661 aacctggatt tagaaagagg atcttgcctt ccatccaagc acttggcaca tgcaagtgac
    39721 catagaggca gatagcggcc tcttcctcct gagcccagta gtccaacttt tgaaagttga
    39781 aattgatgtc aaacaagtga ccatgagttt ggataatctt ggtcgaacca agctcagtca
    39841 ccagacgttc tgggtagccg gcgtagaagt ccatgttccc tttaacaacg cggatgccct
    39901 cccaaagtgg agaatccgga cgtagttcag aatcgccgtt atgaaaaacg gcatcgactt
    39961 tgcccacata gcgatcacgg acttcttcca caatcaagct atcgccatgg gaatcgctca
    40021 ttacaatgat ggtttgcttt gccatgatgg aaatacctcc aaaagtttct taacggctaa
    40081 ggcacggtga gattgactat ttttttcttc cagggttaat tcagctgatg actcacctgt
    40141 ctctcctaca aggaagaggg gatcatagcc aaagccattt tcacccttag gttcaaagtt
    40201 aatataacct gaccagtctg cttcaacaac taaactttcc ttatttgggc tggctacgac
    40261 tagggttgtg tggaactgag ccgagcggtc cttgagttca aagaccatgg ccaattcgtg
    40321 caagagtttg gcattatttt cacggtcagt tgctcccaca cctgcgaaac gagctgacca
    40381 gacgcctggt aagccaccaa ggacatcgac tttgagacca gaatcatctg ccaaaaccat
    40441 cttgcccgtt aattgagaaa tggtttctgc cttaaggcgg gcattttctt caaaggtcat
    40501 acctgtttct gctacttcag gcaggtcagg gtagtcatta agattttcca catcgtagcc
    40561 taacttatca aagatagctc ggaattcctt ggttttacct tcgttacgag tcgcaatcaa
    40621 caaggtttct ctgaccttgc ttgtctcaaa gaaatcatga acattgaccc cttctttagg
    40681 caattctaca tacaagagtt gcccattttc aaccaagagc agggccccat gacgttgaat
    40741 aacttccaag tttcgtccca tttcttgatt aagcatgtct accacaaagg agaacaaacg
    40801 gtaggtagaa ccatagcgta aaacagtaac tgaaagcggg aaaccatact cttcatctcc
    40861 aaatattttg gagaattcaa acagaggaaa atctgtctta tagtcgctca aactgttaac
    40921 gccaccaaaa atactataag acccaacata ccagtcccgg tcatccttat attcataaat
    40981 tttatttgtc ataattctac atgctccaca tgaatctctt tttccagcca ttcttcacca
    41041 atttgtgcaa aactttggct actggctgtt gtgtaaaaac ggtgatggag tggtccagca
    41101 tcgcgaccac gattgatttc aaaataattg agtaagactg agatatcccg tacgcactct
    41161 gccccactat cgatgagctg aacctttggc cccatcacat tttggataat agggcgaagg
    41221 agtggataat gagtacagcc caaaatcagg ctatccacct ttccaaccaa gggacgcagg
    41281 gtttcataga ccaccttctt ggtaacactg gttgacaggg cacctgactc aaccaaggga
    41341 gcaaacttgg gacaggccaa gctctccacc tgtaagtcgg gatccagatc atggattttc
    41401 tgacggtata tgtctgattg taccgtcatg ggcgttccaa tcactcctat tttcccacct
    41461 tgactggact tgatggctgc cgaagctcct ggcaaaatta cacccaagac aggaatatct
    41521 agttgagcct tgatttcttc ccagacgacc gcagtcgcag tgttacaagc aatgacaatc
    41581 attttgacat ccttggtcaa gagaaagttg accagctgcc aagtatattc acgaatttgc
    41641 tcagcaggac gggggccata gggcgcccgc gccgaatctc caatatagac gatttcttca
    41701 tggggaagct ggcgcatgag ctcgcgcaca acggtcaagc ccccgacacc cgaatccaaa
    41761 aaaccaattg gtcgattatc catacagtct tctttctagt cttttttctg attgatcgtt
    41821 cattatgatt ccttgtactg aacgaactga ccgacagctt gatagaatgt caactacctc
    41881 tctcttaatc ataatcaaat atcaatagaa tgcaaggaaa aagtctcatc cctaaaccat
    41941 aaccaacata gtgagaagtc tggaactttc atcccagact tttccttatt tattttttct
    42001 ttttattgtt agcaagggct gccttttgtt ggcggatgat ttggtggtaa acttgttgta
    42061 ccttagcttc gcttggtttt tgaccatttg cactcaaaag agtacgaact gcttcagcat
    42121 tcaaacgtgg gttgtcagca aattcttttt cgatttgctt acgaaccaag tacattcctc
    42181 caagagctcc tcctagaaaa gctagcacaa tcaatacaat tgctaaaagt aaatccatca
    42241 tttttctcct gtttcttttt gagtcccttt cattatacca caaactagcc accctgacca
    42301 gtttgttcta cactttcaag gatggaatag acagcaaaaa gaaccctgct tttctgaaaa
    42361 agaggtctcc ttgctaagtt tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    42421 cacaggttgc tcaaagcacc gctttgaggt tacagataaa actgacacgg tttgaagaga
    42481 ttttcgaaga gtattaattt acataaatag ccagtgtttg atagggtttg agtagaattt
    42541 tctcagacac ttctgcatct tcatagtttg aaatcaaaat ctgtccattt tggtagactg
    42601 ctggcaagtc gatttccact tctttggcat aaaagttatt gagcactagt aacttttgat
    42661 cctcaaactg gcgttcaaaa gcgtagactt gtttgctatc ttcaaaggct ggtttgtaat
    42721 ttccttctga aatgattggc atttccttac gcagtcgaat caagtcttga tagaaggtga
    42781 aaatcagacc tttgatttca ttttctacat tgatatcttt ataggattta ccaactttca
    42841 accatggagt gcctgttgaa aatcctgcat tttcagaagt atcccactgc atgggaatac
    42901 gtgaattatc acgcgactta gcttgaataa tctggaaggc ttcttgctga ctctttcctt
    42961 cttctaagag catctgatag gcattaagcg attcgacatc cacataatca gtcatagaat
    43021 catagtctgg gtcaatcatc ccgatttcct cacccatgta gatataaggt gtcccacgtg
    43081 acaggtgaat gctggctgct agcatggtgg ctccttcctt gcggaagttt tgaatatcga
    43141 caaaacggtt caaggcacgt ggttgatcgt gattgttcca aaagagggca ctccaaccgt
    43201 ctttatcact catttcctta ccccaactat ggtaaagact cttcaactct tcaaaatcaa
    43261 agggagccaa ggtccacttt tgtccatcct tatagtccac cttgaggtga tgaaaattaa
    43321 aggtcatgga taattcctga cgatcaggcg acgaatagag gacacagttt tccatggtgg
    43381 tagaagacat ttccccaact gtcataaagc tatcgtcaga tccaaaagtg gcttggttca
    43441 tcatacgcaa atagttatga acgatgggtt tgtctgtata agctggcttc ccttcatttt
    43501 caggacagtc cactgaaacc tcgtccttac cgatcaaatt gatcacatca aatcggaaac
    43561 ctttgacacc cttgtcgcgc cagaaattaa caaccttgaa aagctcctta cggacattgg
    43621 aattgcgcca gttaaggtca gcctgggtct catcaaatag gtgaagatag tatttcccag
    43681 tatccccgaa aggcgcccat gcagaaccac caaacttaga ctgccaatct gttggttggt
    43741 cttggatgaa gaaaaagtct tgataatact tatcaccagc tagggctttc tgaaaccatt
    43801 catgctctgt cgaacaatga ttaagtacca tgtccagcat aaagtcaatc ttgtgctctt
    43861 taccgacaca caccatttcc tcaaaatcag ccatatcacc aaaaagagga tccactgcca
    43921 tataatctga aatatcgtaa ccattatccc gttgagggct tggatagaat ggattgagcc
    43981 agaccatatc cacacctagt ttggctaaat agggaatttt ttcgataatc ccacggaaat
    44041 ccccaatacc gttttcagtg gtgtctttgt aagattttgg atagatttga tagactactt
    44101 ttcctttatc aagtgtcatc tgtttctcct tttctgataa aagggaggaa gcagtcttcc
    44161 gtccctattt gtgctatttc aattatactc aatgaaaatc aaagaacaaa ctaggaagct
    44221 agccacaggt tgctcaaaac actattttga ggttgcagat agagctgacg tggtttgaag
    44281 agattttcga agagtattag attcgtgtag cgaccatgag agatgctcca gcttggatcg
    44341 ttgtcggata agttccagga atagtcgctg tataagcatc ttggttggtg atgataacag
    44401 gagtttctgt caccagacct gcagccttaa tgacatccat atcaaaacga atcagttgct
    44461 gaccaactgt aacgtgatct ccttggacta caagactttc aaaacctttg ccatcaagac
    44521 ctactgtatc cataccgatg tggatgagca attcaactcc ctcgtcagag acaatgccga
    44581 tggcatgctt ggtagggaaa agaaccgtca ctgtcccatt aactggagag gtcaactcac
    44641 cttggcttgg ttcaatgacc agaccttgcc ccatgacacc tgatgcaaaa ataggattcg
    44701 tcgcttgact caattctttc acttggccag ttagtgggct gataatttct accgaagtaa
    44761 gttctactgg ttcatggttc acaaattctg cttcttcttg agcaacgaat tctgcctgca
    44821 agttcgtatc gccctctgtt tttgtaaaga gaccagcctt gcggaagaag aaagtcaaga
    44881 gcattggaac aacaatcgca actagcatag ttcctgcaaa tggcagcatg tattgaggtt
    44941 gaatagagag aatacctggc aaaccaccga taccaataga agccgcagtt acattaaaag
    45001 taacggataa catgcctgca agggctgaac cagtcatccc agcaacaaat ggataaatat
    45061 attttacgtt aaccccaaaa agagctggtt ctgtaacacc gagataggct gaaatggttg
    45121 caggaagtga aacctgagcc tcacgctcat catggcgatg catgaaataa taggcaaaca
    45181 cggctgagcc ttgagcaata ttagaaagag caatcattgg ccatagggca gtgccaccag
    45241 catccgcaat caattgtgta tcaatggcat tggtcatatg gtgcagacct gtgatgacaa
    45301 atggagcgta gagggcacca aaaattgcac cgaagagcca tttaactgga ccagttaaac
    45361 ctgccaagac aactgatgaa agtccttgtc caattgtcca accgattggt cccaaaacag
    45421 tatgagccaa aatcaaggct ggaatcaatg acaagaaagg tacaaaaatc atagaaatga
    45481 cttctgggat atgcttgcgc cagaagattt caagataaga cagactcaaa cctgcaagca
    45541 aggctgggat aacttgggct tggtaaccga tacgattaac agtaaaatag ccaaaattcc
    45601 aaacccagtt tgccgcgata tcagctgctg gcgttgaagc aaccgcatag gcattgagca
    45661 actgaggcga taccaaacag attccgagaa caattcccaa aatttggctg gttcccatct
    45721 tacgagaaac agaccaagta atccctactg gtaagaactg gaagatagct tcaccaggca
    45781 accagaggaa gtgattaacc cctgcccaaa actgagagga ttctgtgatg gtcttgccat
    45841 ccaacatcga ccaatggaca ccttccaaga cattacggaa accgaggatc aatccaccaa
    45901 caatcaaggc tggaataatc ggagtaaaga tttccgccag agtggtcata acacgttgga
    45961 ccacgttttg attactctta gctgcagact tggctgcttc tttggaaaca ccctcaatac
    46021 ctgaaacggc tgtaaaatca ttataaaaga tgggcacgtc atttccaatg attacctgaa
    46081 attgacctgc atttgtaaag gttcctttaa cagctggaat tgactcgata gctttaacat
    46141 tagccttctt atcatctcct aaaacaaacc gcatccgtgt cgcacagtga gttacggcag
    46201 tcacattttc tttgcctccg attgcctgaa gcagatcttt ggcttcttgt tcaaattttc
    46261 ccatttgatt ctccttatac ttgtcaaagc aagtttgatt tgataagtat attgtaaacg
    46321 ataccaaact tgtctgcaac ttgtttggta taaaaagggt gtttttttgt aaattttcta
    46381 gcacttgtat ggtaaaatag atacaggtgt tcattaaact agactaaaaa cctatttaag
    46441 caggcaaaat gaagaaatac caacaattat ttaagcaaat ccaagaaacc attcaaaacg
    46501 agacttacgc tgtcggagat ttccttccta gcgagcacga ccttatggag caatatcaag
    46561 tgagtcgtga taccgtccga aaggccctgt ctctcctcca agaggaagga ttgatcaaaa
    46621 agataagagg gcaaggttct caagtcgtca aagaagaaac cgtcaatttc cctgtatcca
    46681 acctaaccag ctaccaagaa ctagttaaag aacttggact gcgctctaaa accaacgtgg
    46741 tcagtctgga caagattatt attgataaaa aatcctcact gataaccggt ttcccagagt
    46801 ttcggatggt ttggaaggtg gtccgccagc gtgtggtgga tgatctggta tccgttctgg
    46861 atacggacta tctggatatg gaactaattc caaatctcac tcgccaaatt gctgagcagt
    46921 ctatctattc ttatatagaa aatggcctca aactccttat tgattatgct cagaaggaaa
    46981 tcaccattga ccactcaagc gaccgagaca agattctcat ggacattggc aaagaccctt
    47041 atgtcgtttc gattaaatca aaagtctatc tccaagacgg acgccaattt cagtttaccg
    47101 aaagtcgcca taagttagag aaatttagat ttgtagattt tgcaaaacgc aagaaataaa
    47161 agactgagac accagatctc agcctttttc tttatcccaa aactaattca tcactgacca
    47221 gactttggcc actatttttc tggaagagat gcataaggtc ttcaactgtc agatgctttt
    47281 tctcttctcc cttgacatcc accactatct tgccttgata gagcataatg agacgattgc
    47341 cgtactcaat cgcatgattc atatcatggg taatcatcaa agtcgtccac tgatggtgct
    47401 ccacaatctt ttgcgtcaag ttcatcacca tttgactggt tttcgggtca agtgccgcag
    47461 tatgttcatc caaaagtaaa agttttggtt tcatcagatc tgtcatgact agagtcaaag
    47521 cctgtctttg tcctcctgag agatattgag tatctacttt taagcggttt tcaagaccaa
    47581 tattcaactc cttcaaggcc tcttggaact ggattctatc cttctccttc acgccccaac
    47641 caagccctct cttctgcccg cgtctcaagg caatagccat attctcctca atcgtcaaac
    47701 gagaagctgt tcccatctta ggatcttgaa aaacacgggc aatatccttg gctctctttc
    47761 tgacactcag atttttaatg gatttccctg ccagtagaag gtccccttcg tccaccgata
    47821 gattgccagc caagatattc atcaaagtgg attttcctgc tccatttcca ccaatcacag
    47881 agataaaatc tccctcttca acctctaaat ctaatccttt gaggacatgg ttctcattga
    47941 ccgtccctgc ttcaaatgtc ttgtgaatat tttcaagtgt taacaaactt gtcataactt
    48001 tctcctccta ttcatttctc aatttcagac cacgaatctt taatctcttt tgcaattctg
    48061 gtgcaaataa aaccaaagcg agcaagattg cattaaagag acgtaccaag ttttgatcta
    48121 gatttggaat ttcatagata tttaaaataa tcaaacggta aacaatagca ccgattccga
    48181 tggataataa gcggcctcca atggtcaagt cgtgtatcaa gacttccgca ataatcaccg
    48241 agctcaaacc aacaacaatg gttcctgtcc cagaagtcac atctgaaaat ccatcatttt
    48301 gggcaaacaa ggaaccacat agagcaatca aaccgtttga aatcatgtaa ccaacaatct
    48361 tcatggtgtc tacattgact ccattggcct cactcatcgg gatattatcc ccagtcgaac
    48421 gcaagaccaa gccaatctct gttttcatca aaagggtcaa gaccaaacaa acaagtaaaa
    48481 aacaggccaa actaagtgag aaaacagttc cttcatttgt cagacccaag ctcgccaact
    48541 gtttaaagac ggttgcagaa tctcccaagg aaagattggg tacactgccc atgattttaa
    48601 tattgattga atagagccct gtcaaggtca caatccctgt caagagagct gggattttca
    48661 tcttggtgtg gagcattcct gatacaagac ctgctaccat acctgccagc aaagcaagta
    48721 aagtcgcaag ccaaggattt gcccctgcct gtatctgtga tacaacgact gctgccccca
    48781 gaggaaaggc tccctcagca gtcatatccg caatatccaa aatacggaaa gtcaagtaga
    48841 ccccaatcgc cacaatcgac cacaacaaac cttctgataa actagataac acaaaattca
    48901 tcttaatcct ccttattcct tgccttctaa cttactaata tcaattccca atgcatctgc
    48961 catttcttga ttggtatgca attccagttt ttcaggcaac tcaactgcta tattttctgg
    49021 tttctcacct tttaaaacac gaatcagcat gcgagctgtc tgacgtccca attcttcata
    49081 attggttccg tagttataca agccaccaac agcaatcatt tctgttgaac caccgaatac
    49141 tggaaccttg tgtttaatag aaacctgctt aactgtttcc atggttaacg aaatgatatt
    49201 atcagttggg acaaaaacca tatccacctc tgccatcaaa ctctctgctg ccgccttgac
    49261 gttattactg tccaagattg ttttttcaac aacggtaaag cctttttctt tcagaagtcg
    49321 cttagcttca tccttttgaa caaccgaatt gggctcgctc tgagtataga ggattccaat
    49381 cgttttagcc tttggcaaca ctttctttat caaattgatt tgggttgaaa tggcatctga
    49441 tgactgatcg cttgtcccag ttacattgcc cccaggatgt tctcttgact caaccaactt
    49501 ggcactgact gggtctgtta cagctgaaaa gataactggt gtcgtttgcg tcgtattggc
    49561 caagctctga gcagaaggcc ttgcgatggc tagaacgaca tcgctggatt ctgctagttg
    49621 ctgggaaatc gtttttagat ttctttgttc tccctgtgca ttttgcaaat caatctcaat
    49681 attttccccc tcaacatagc cttgtttggc cagcttatcc acaaatcctt ctctagtagc
    49741 gtataaggac tggtgggtaa taaattgcga aataccgata cgaaagacat ctttttctta
    49801 tctgccttca actgatgcaa actgatcaga gaagtcaaga ggagccccac taccaagagg
    49861 gggctagtga ttttcgaaca actttcataa tgaaactcct tctcagaaaa gataaaacaa
    49921 aaaaccgcct agatactatc taaacggata cttgaaataa cctaacaagt tacaacttag
    49981 ctagtccatt tagatattca tctatatgga ccacaatcaa aaatcttagc cacatagata
    50041 caaacaaatt gcttgaactg tttgcatcca tggtgacatg tctacaaaca ctatctaaag
    50101 tagctaaagt aaaagttttg attcatagtt acggcttgtc tcttattcat ttctttttct
    50161 gctttctttt ttgatgcttc ctgtcctacc acctttttca tcacctgtca ataacatttc
    50221 ataattttta aaatttttca aaaattcttt caggaagctt tcaaagtttt tcaaatcagt
    50281 ccaacaaaaa aagttttata atttccataa aaattgacat ggaaattata aaaccattac
    50341 tagtttagtc ctttttgata acgtgccaat tcggcttggt tcgcccaaac atagtgacct
    50401 ggacggattt ctaccataga tggcttatca gtctcatagt cgtgttgact tgggtcgtaa
    50461 accttcaaga ccttcttacg ttccaagatt ggatctggga ttggtaccgc tgaaagcaag
    50521 gcttgagtat atgggtgaat tggattgtta aacaattctt ctgtttctgc aacctctaca
    50581 ataacaccct tgtaaataac tgcgatacga tctgaaataa agcgaacaac cgacaagtca
    50641 tgggcgatga agagataggt caggccgagc tctttttgga attttttgag caagttcaag
    50701 acttgggcac gtacagaaac gtccaaggct gaaattggct catctgcaat aacaaagtct
    50761 ggttgcatga ccaaggcacg ggcaataccg atacgttgac gttgaccgcc tgagaattca
    50821 tgagggtaac gagtcaagtg ctcagcaaga agacctactt cacggataat attttgaact
    50881 ttctctttac gttcttcttc atccttaaat aaacggtgat tgtaaagacc ttcagaaata
    50941 atataatcaa cagtcgcacg ttcattcaaa cttgcggcag ggtcttggaa aatcatctgg
    51001 attcgacgaa tcaattccgc agcttgttca cgcgatttct taccattaat cttttgacca
    51061 tcaaaaatga tatctccatt acttgtatca tttagaccga tgatagcacg accaatagtt
    51121 gttttcccac taccggactc acctacaagc gagaaagttt ctcccttgtt gataaagaag
    51181 ttagcatttt taaccgcgac aaacttctta cttccttcac cgaaggaaat ttctaaatct
    51241 ttgatttcta ctaatttttc agacatttcc ttcctcctag tcagccagat gggcaaatcc
    51301 cattttttca cggatcttat catggagatt tgcaatcaca gctggttttt ctacttttgg
    51361 agcatcctca tgaagaagcc aagttttagc ccaatgtgtc tctgatactg agaattgagg
    51421 agctttttgt tcgaagtcaa tctgcattgc gtagtcagaa cgcaaggcaa aagcatcccc
    51481 tttcaggtca gtataaagtg acggaggtgt tcctgggatt gagtaaagat cccctttatc
    51541 atcagcaagc tgaggcaagc tagacaagag actccatgta tatggatggc gagggtcata
    51601 gaagacttcc tcaaccgttc catactcaac gatttctcct gcatacataa ccgctacctt
    51661 atccgcaata cttgccacca caccaaggtc gtgggtaata aagattgttg tgaaatgata
    51721 ctcgttttgt aaagatttta gcaaatcaat aatctgagct tgaatagtta catccaaggc
    51781 agttgttggc tcatcacaga tcaagacatc aggtcggcag gcaagggcaa tcgcaataac
    51841 gatacgttga cgcattcctc cagaatattg gaatgggtat tcattaaaac gtctatctgc
    51901 gtctggaatg ccaaccttat tcatgtagtc aatggccaat tctttcgctt ctttagctgt
    51961 ttttccttgg tgttttacaa taacttctgt aatctgacta ccaattgttt taatggggtc
    52021 caaactagtc attgggtcct ggaagatagt cgcaatctta gcaccacgaa tttgttccca
    52081 atccttgtga gaagataaag ctgtcaagtc ctgaccacgg tagtcaatac taccttgggc
    52141 aatgcgacca ttttcttcga gcatacctgt gaaggtcttt gtcaaaacag atttacctga
    52201 tcctgactca cctaccaagg ctaatacttc tccttcgact agttcaaggg aaacgccgcg
    52261 aatggctgtc aatactttgt cacgaacgtc aaattccacg acaatatcgc gagcagtcaa
    52321 aattacattt ttttcttttg tcatttctac tcctatctat gtgtacgtgg atcactagca
    52381 tccgctaagt tttgaccaac tacgaaaagg gacaaggata ccaagacaag ggttgtcaat
    52441 ggaatccaga acaagtaagc attggttgtt acgttttgtg aataatccga aatcaaacga
    52501 cccaaacttg gcactgtaat cggtaatcca agaccgaaga aagacaagaa ggcttcgtat
    52561 gagataaagc ttggaagcat ttgagtcatg gttgtcacaa taacagatac caattgaggc
    52621 atgatatttt tggcaacaat cttcaaggtt ggtgttccca aagtacgtga cgccaagttg
    52681 tattccaagt cacgatagcg caagatttgc acacggatca tgaaggcaat accaatccat
    52741 gttgttacgc tcatggcaaa aatcagattc cagaatccag ctccgattga gtaagtcaag
    52801 acaataacaa tcaaaagagg tgggatgttt gagatgacgt tgtaaacttc catcatgaca
    52861 cggtcaactg attttgaaat accccaaata ccaccgacaa aaacaccgat aaccaagtta
    52921 atcactgtcg caatcacaga aatgaggatg gagttacgag ctccgaacca gacaccgtca
    52981 aagagcgatt taccgttact gtcagtaccg aaccaatgct ccgcatttgg cttgatataa
    53041 cgaacactaa agtcgtttac cttgctgaca tcattgaaat caaacttaga aaacattggg
    53101 tagatgaaac ttatcaaaat gatggctacc aagattccca acatgactac agttgatttt
    53161 ttcttcataa attgtttaaa cactgatttc cagtaagaat atgctggcgc atcaatagtt
    53221 tcagaggcaa aatcgtcacg ttttacaaac tgaaattttt ctttatcgat tgtagacatt
    53281 atttgcctcc tttctcagtc aatttaatac gtgggtcaat aatagtcatc caaatatctc
    53341 ccaaaagacg tgagaagata gaaatacatg taaagatgaa gacaagacca acgaccatag
    53401 agttattaga tgcttttaca gagtcaatca acattttacc catacctggg aaggcgaaga
    53461 ctgtttcagt aagggttgca ccaccgataa ccccaataat ggcaccagga attcctgaaa
    53521 ccagcggaac catggcattt ttaaagatgt gtttgtttga aatttctttt tcagacaaac
    53581 cttttgcacg agcgaaacga acaaagtctt gagattgcaa gtcaatcatg taacgacgaa
    53641 tccaaatggc tgtaccagga gcacccaaca aaccaaggat gactgctggt aaaacgtaag
    53701 aacgccaatc tccagctccc aagataggga atgaatctgg aagggaaata gatgatccaa
    53761 tcaatcgaac gatgtaaacc aaggcaatcg ttggaagagc aagcaagaag gtcaaagccc
    53821 ctgttgagag gctatcaatc caagtgttct tgaaacgagc catggctgaa ccaagtggca
    53881 cggcaagagc ataggcaaga accaaaccaa tcaaaccagt aatagcagag ctgacaatca
    53941 tagatggata ttggtaatta ctttcagtcg ctgtataagg atcatctttc ccatagctag
    54001 ctacttcacg agagtcagcc tgactaggtg acttgtaggt tcttgagtaa atatttacag
    54061 aagacgtttt cttacctgtt gggaactgaa cttgggcagt tttggtttgt ccttgacctt
    54121 gagtaataac ctgaagaact ggtgtattag cataggttgg gtaagagtca cctaaattca
    54181 agttcacaaa gttttgatga acaaatggga actgactgtt aaagtacaag agatatttat
    54241 gtttagttcc tgaaccgacc aatgaccatc cgatagctgg atcattttca aaacgaaggt
    54301 agcgtttcaa gtctggattt tcagggtctt ggattttatt tgtatggtca atgtcaatca
    54361 agttagcata gaagtgaaaa acacgttcaa aaattggaat ttcacgagta gcatagaatt
    54421 gaccactttc agtaaattct cccaaagtcc aaccatgacc taattgattg atgtactttt
    54481 cataaatagc tttattggtc gcatttgctt ctactgttac agaagaatcc atgctacttg
    54541 ccttttcttg caactcttta gtatcgtaat actcaatgta gcccatacgc tcaaacacag
    54601 tattttcata gttatcacgt ttatcagccg ttgtcgcaat tttattatag ttaggatcct
    54661 gcttgaaaat caattttcga ggaaccaagg tatagataat cgtgtaggtc aaagtcgtta
    54721 ctaagaaaat cgaaaccaat gaccgcaaaa cacgcataaa aatatatttt ttcatattat
    54781 ttcctttaaa aatcccaaaa gaaccttctc ctcatggaga gaaagttcta ttagaaatta
    54841 tttacttcac atgacttgcc aattcttttt gagctttctc atttgattca gctttttctt
    54901 tcaaccattt ttcacgagct ttttcatact cttccttagt caccgcttta tcttgtaatt
    54961 tcaaatattt gaagtaaaca tctgacccct tagagcctgt ttgcgcagaa gctccagtaa
    55021 atggaacaat tcgtgaaagc actggtgctg caccagaaga agccatagca ggaataaaga
    55081 gtgaactatc tgtcaaccat gcttgagccg ctgcatattt ttcataacgg acattcaagt
    55141 cgcttgtctc tttggcagct tcatcaacta atttatcgta ttctttcaaa ccaacttgaa
    55201 ctactgaagg gctatttgga ttatcaaatc ctaaatatgt ttttgtagtt tcactgctag
    55261 ttgtttttaa aatatccagg taagtagatg ggtcttgata gtctggcccc catgaaactc
    55321 ctcccgatac atcccaatcc tcagatgaag cattggcagc atagtaagta atattaagga
    55381 attcatcact tgtcatttgt tgaatatcaa caacgacatt ttcaacacca agaactgttt
    55441 ctacagattg tttaaaggac tgaatacgag atatatagtt ttttgatgct tggtctactg
    55501 gaacgtccag atgaatagga aactgaacgc cgtctgcttc taaagctttc ttagctttcg
    55561 caaactctgc cttggccttg tcagcattga ataaaccatc ctgcccatca gctaaattca
    55621 cacctttcca ctcatcacca taagcaggaa gttgagcagc gactaaatca ccaaaggtct
    55681 tctcaccagc tgaaacaaag tctggtttta caaataaatt acgaactgct aaagctgctc
    55741 catctttacc attgatttga gctgagtaag ctgagcgatc aagagcaaaa ttcaaggctt
    55801 gacggaaatc tttgttaagc aatgccttct tagtagctac tttctctgaa tctgtagttt
    55861 tagaagtata gttgtaactt tggcgatcaa tattcacacc cagaccagca atcccagagc
    55921 ctgattgtgt gtaatagata ttgtccttgt attcttctgc aaccttagaa tagttggagc
    55981 tggtagggta aagacgggca taactataag ctccactagt gaagttacgc tctagcgact
    56041 cctgatctga tccatcatag taagctagat tgatagtatc taggtggaca ttttctttat
    56101 cccaatattg ctcatttttt acaaactcta cagaagattt tgcagtcaac cctttcaaca
    56161 agaatggacc attataaagc aaggatgtcg gatctgttgg tttagcaaaa tcgcttcctt
    56221 ttgatgtttc gaattcttca ttcagaggcc agaaaataga ataggtcaac ttagagttcc
    56281 agaacggttc aggctggttc aaagtgtatt gtaacgtata atcatcaacc gccttgacac
    56341 caactgttga aaaatctgtt gaagttcctg atagataatc tgccaagcct ttaaccgaat
    56401 tttcagctaa atacatagct tctgattttt tatctgctgc gtgttttaaa ccgttcacga
    56461 aatctttagc cgtcacctct gcatattctt ctccatcaga ggtaaaccat ttaacccctt
    56521 tacgaatctt ataagtgtag gtcaaaccat ccttagagac ttcccaatcc tctgcaactg
    56581 caggagcaag attaccgtaa ttatcgttag tgaataaacc atcaatccca tttgaagtca
    56641 ctactgttgt actattttta cttgaaatca ggtagtccaa ggtttctggg tctgctgtat
    56701 aaacatagcc ataagcttta ggggctgatg aatcagatga ttttgaagaa ctgcatgctg
    56761 caagtacacc tgctgctaat aaaacaagac ctgctgtagc aaatacacga ttttttttca
    56821 ttttctactc ctctgtttat gtgaattata gattgacaac cattatatca cattatccat
    56881 taaaaatcaa acaaattttc agaatattta ggcttgttgg cacaaatttt tcattttttt
    56941 tgaatatatg attcaaattg tcgttcgaag tgtcaaagac tacagtgaaa ataggaaatt
    57001 tgacacagaa attttggagc ttaggaagac atacagtaaa atgaaatacg gacggaacaa
    57061 tgtgattttg gaattcaaat taaattataa caatattgta gaagtatcat tctagtattc
    57121 aagattcagt ttactatgtc ttttcacacc aaccttattc cgaattcaat tactttcgtg
    57181 atttacacat atagattaag actatctttt atactttaaa atttctcgct accttgtcca
    57241 ctatatgctc ctcgctatca cgtttctatt catagcctac gatttcacta ttgctttctc
    57301 tgacaattct tatttcctgc gtcagactta aaacgatcta tccccagacc attttaatcc
    57361 gctacctcac gatagtcagg cttggggagc gctattgtat tcaccggtag tggatcccta
    57421 cagaggactt acacctcaga tgcacgacat gcccatcgta taaaaaaatc tcctacccaa
    57481 ggtagaagat ttcaaactta taaaacttaa tccgtcatgt ccgataccaa cattcgatgc
    57541 tccaatggaa tactgcacat aactagcaag aaaataaagc ctgactgaat ccagaagaga
    57601 gccaagtcaa aaattccgtg cacagcaacc actgtaagga aagatagata aaggccgata
    57661 atcggacgtt tccccgactc ctgactcata tccatcatca agcgaacagg agcaacagaa
    57721 gacaaaacta ataaaatggt acccacaatt ccgtaactca aaatcgtatc aatataaaga
    57781 ctgtgggcat gttcatgata aggagcatgt atccgaggat aagagtgcat ataggtcaat
    57841 ggcccttcac cccaaaaagg attttgctta aacaaggcca tcccagcatc ccagatagaa
    57901 atgcgttctt ccatagaaga gtctaaagta cccattcgaa ctcccaaatc actagaaaag
    57961 aggaaactca aaccaatcgc gaagacccca atactaagcc aaaaggcctt ccagttttta
    58021 atagtcgtaa agagatagat aattgctcca gcgataatag caggaaaggc agttcgattt
    58081 tgagtaaagt tcaaaccaaa gagattaaca aagcctgcaa tcacacagaa tactttcaac
    58141 caattcaact tggtcgttgt aaacagatag aaagcaatca taatacagaa acaacaaata
    58201 attccataat aattaggatt aaagaaggtc acttctgccc ggttctgatg ccacacctgc
    58261 atattgggtg aaagaaaagc atagttaaat ttcttcacaa tttggaaatg ttctaaactg
    58321 gcaaaagcag ctgacaagac actaccaaac aagacgaact gcaaaatcaa tcgaaagaat
    58381 ttatgggata aaatcgactg atagtgcaaa aagaaaatag taaatagaaa cattcctact
    58441 gaagccacaa gacccatcca attttgtgca agaatggata taacagtact atagctaaga
    58501 aaaagaagca gcatcggatg ctcccccatt ttctgaagaa tacttttcat gtctcctgta
    58561 aaaatcaaac tgataatata taaacagagt acaactacaa aaagataaaa gggtaaaaag
    58621 atacttagga taattcccaa taaaatcagc tctttactag acaacccctt cagcttttca
    58681 ataaagccta ttgatttcaa aatgaatcct ttctctccaa atcagctgat tcagataata
    58741 gtaagctatc ctatattgta ccactttttt agcaatttga aaacaaagga aacgttttcc
    58801 aaaataaaaa ccctatttta tccaccatat caaggcttca aaatgatact tcaactccat
    58861 tctcaattac ccgataagtc tgattttgca aatcaatttc tactactgct gttacggact
    58921 tatctttatt ttgacgtttg attacaatgc tgtgagctgt tggtgtctct atctcagtag
    58981 tcccttctag atcaaaggct tctgaacggt tacggaaaga aaatagattg agaagggcct
    59041 tcacaacagg tcgttgcact tcttttgcta tttcctcgtt gctatagtaa tgacgattaa
    59101 tatttcgacc ttctttagtt tcttctaata atttcaagtc attcttgcct gctaatagac
    59161 ccacatagta aacctgagga atacctgggg caaaagcttg aattagacga gcgagaaaat
    59221 acttgacatc atcatctcca agcgctgaat agtaggttga attgatttgg tagatatcta
    59281 agttgttata ctcggcacta gagtacttac gtttgacatt ggctccaacc ttatagagtt
    59341 catttgaagc atagtcaatc tcctcatcgg tcaggatatc cttgacatct actactccaa
    59401 tcccatcatg ggtatctagc atcgtaaatt gcttcatcgg gctcatcttt aaccacttag
    59461 ccaaacgctc tgttctggaa ctgtaaagag tataaagtgt caccattgga agagcaaaat
    59521 cataaacata gtaatcatgg tctgctattt taaactgaat cgaatagtgt tcatgaatct
    59581 caggtaaaag ctctgtccca tactcagcag cgatatctcg aactttgtcc aataaatccc
    59641 aaatatctgg ttccacaaag aaatcattag tatccaattt cttcactgca taagcaaagg
    59701 catctagacg aatcaaatca cacccattac ttgccaagtg ctgaatggtc ttacggataa
    59761 attccatagt tacttctttg gtcacatcaa gatcaatctg ctcctcacca aaggtattcc
    59821 acaaatgttc cactgaacca tcttcaaaca caatctcttg ctttggtgca cgatccttac
    59881 gcttgtaaat taaatctaca tcagactgtg tcggacggtt ttctggccaa aacttatccc
    59941 agtttaaaaa gagagcttta aattcactgg cttcatgttt ttcttgatag tccttataat
    60001 acttggattg acgagaaata tgattaatca taaaatcaaa cataagataa tatttctcac
    60061 ctaaacgctt aacatcctcc caatcaccaa aagctgagtc cacttcgtcg tagtcaactg
    60121 gcgcaaatcc acgatcacct gttgatggga aaaatggtaa aaggtgaact cctccaatag
    60181 catctccaaa atgctcttcc aaattatcat ataagtcttt aagattattt ccaaggctat
    60241 cagaataggt aatcaacatg gttttatttt gaattggcat cattactctc ctttttctaa
    60301 ttgaagccaa gtctcatatg atctggcttc ataaataaaa ttcattttaa atctctattt
    60361 atcatcaaac tcgtactaat atagactgtg ataaacaaag tactactttc ttgttttctg
    60421 catagaatta tcaacaagct aaactcttcc tctgtgtcaa agactataga ttccatgagc
    60481 tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtactcaag tacagcctgc
    60541 ggctagcttc ctagtttgct ctttgatttt cattgagtat tacttcactg ccccgttgct
    60601 cattcctgaa atgatatggc gttggaagaa gagatagaca atggtgatac tgataatgcc
    60661 gaccacgtaa gaggcaaagc ttggtccgta gtcgttgaaa tattggcctg cgtagttgta
    60721 ttggaacaaa ggcagagtcc acattttgga atcccggttc aagacaagga gtggcaacat
    60781 gaagtcattc cagaaccaaa gggcattgat aatcatggtt gtcgcatgca tcggtttcat
    60841 cattgggaag atgatgcgga aataggttgt aaattgatta gccccatcga tctctgctgc
    60901 ttcatccaga ctttctggaa tcgagatttt gatatagcca acatagagaa agagggtctg
    60961 tggaatcgca taggtcaagt agagcaagat caaaccaaag gtattagcca aaccgagttt
    61021 actcatcata accgtaatcg gaatcatgat gacttggaaa ggtacgaaga ttccgaggat
    61081 taagagggta tacatgatgg taaaggcttt tcttttactc atattgcgag cgatggagta
    61141 ggctgccata gggataaaga tcattactgc aagtaaagac aagacagtga tgacgacaga
    61201 gttccaataa tagcctccaa tcccatcagc taagagacgg ctaaagttgt cccatgtgaa
    61261 gttggttgga aagccaaaga aattatctac aatatcctta gtgggtttga aggaactaaa
    61321 gagggtagca aggagcggca ctaaaatcag aaccgatcct agaatcaata gaatgtattt
    61381 gccaatcagg gcttttcttt catcttgttt catcatgctt ctcctcttaa atttcaaatt
    61441 tcttagatac tctcaattgg atgatcgaaa tcactacaat taagaggaac aagattacgg
    61501 caatggcatt ggcataaccg aattggttgt ttttaaaggc atagttataa accaagagcc
    61561 caagtgaggt tgtggcattg tttggaccac caccggtcat ggcaaagact tggtcaaagg
    61621 cagtcagccc accttttagg gctaggataa agaccataga gacacttggt agcaagtaag
    61681 gcaattcaat gttccagaaa acttgcttgc tagtcgcacc atcaatcctt gctgcctctg
    61741 taatctcagt tggaatagat tgcaaaccag ctaggaagat gatgatgggc atagccaccc
    61801 cttgccaaag aaggacaaag gcagccgcaa agattgctcc ccacttagtc cctaaaagac
    61861 tggtttggag aaattcaata tgaagggcat tcccaatcgc tggaagaccg tagttgaaga
    61921 cttgcttgaa gatcaaagcc actgtcaaac cagataaaac agctgggaag aagaaccaag
    61981 cacggaagaa ggtttggcct ttgattttag agttcaagac acgcgcaatg aagatcccga
    62041 gtgcaatctc accaaccacc atggcaatcg taatgattgc ggtaaagcca atcgcattca
    62101 tgaattttgg atccatgaag aggagcttaa agttgtttaa gccgacaaat ttgtagttat
    62161 aagtcaatcc tgtccagttg gtaaaactgt aaaaggctcc ttgaaacatc ggcacataga
    62221 agaaaattgc ttgtaacaag agggggatga ccacaaaagc ccatgcccaa tatttttgta
    62281 atactttttt catagtctct ctactcctaa tccacatccg ctttcatcgg gttaaagaag
    62341 gcattcaaat cattgaccat gccttgttta tcaccggtca agacatagtt catggtcaag
    62401 gtatggaagt ctgcttcact ggtccagtat tgttgcaacc agaccaagtg acgatccgta
    62461 aaggcatatt cggtcatacc agcaagcggt gaatcttctc ctgcttgttt gaccccttcg
    62521 atcgctgttg gagatccgtc cacatcgtag tatttttgca tgacttctgg acgggtcata
    62581 tattccacaa aggcattggc ttcttttgga tgtttggtgg tggctgagat agaccatgcc
    62641 aagtctcccg caccaacggt taagctttgt cctttttctt ttcctggaat catgaaggtc
    62701 ccaatcttaa agttcggttt ttgttcatta atcgctgtga tcgcccaaga cccatttggt
    62761 gtcatgagga catccccacg tgcgaaggct ccgataacat cggtatagcc agcaccttcc
    62821 cagttctttt gcttagagcc attgatgcga aggatgtcca tgaccttgat atcatctttc
    62881 ataatcggat ccgacaattt aatggcattt ggttgagaat aacgaaggta ttgatttgct
    62941 tcttttcctc cacctgttgc tgtcgcaaag gctaattgat tgtaaccatt gagtgtccaa
    63001 gcatctgcac ctgcaattcc aaatggtgtt tgtcctttag caacgatatc tttgactaac
    63061 tgttcaaatt catcccaggt ttcaggaacc ttcaagccca gttcttcgaa tttatctttg
    63121 ttgtagtaaa ttccataagc attagctgta aaaggaacgt tgtaaacttt ttcgtttaca
    63181 gcatattttt cagcgtagcc atttttcacg cgtttcaggt agtctttgtt gctcaaatct
    63241 tcaaaaacac ctgcttttgc ccattcttgc agttcgatgg actgtgggta aatattgacc
    63301 acatcaggca catctcctgc gagaacgcgt gtcttcaata cttcaccagc atttggtaca
    63361 ttgacgactt tgaccttgat cttagggttt tccttctcaa aatcacgagt gatttcttcc
    63421 aaggttttgg tcatttcttt tttctggttg aaatactcga tggtcactgt gccatccgca
    63481 gatttaccat agttggagca agcgccgagc ccaaacaaag ctaaacctgt agttgcaaga
    63541 agtccgattt ttttatacca ttccattaga aagcctcctt tataaattta tacaccctta
    63601 ttgaactgca ccccaaaagt tagacagaat aaatctaact tttggggtca gtacatatca
    63661 tagttttcta aaaatatact gtctactcaa aaaatctcct tgggataaga taacagttaa
    63721 gcccgcatac attagttctg cacctgagta aacttcgcca ttttcctgta atttatatag
    63781 tccctcttca tccaaatctt ttaattttaa agttgtttcc atggtctcta caacagataa
    63841 aacgcgaacg taggttacaa tcgtttgatt tccgtaatta aattgtacag ctgcttcatt
    63901 ggatgcagta tcaggattaa ttagtctata ctgctgtcct aactgaacta ctggtcgtaa
    63961 ttctttatac aagttcacct gattagcaat cgtagctttc tcttcatctg ataaatttgt
    64021 caaatcaagc tcatagccca aatttcccat cattgctaca tggccacgtg tttctaatgg
    64081 tgtcattcgt cccatctgat gattcggtac tgctgacaca tgagccccca tagaaatggt
    64141 tggatagaga taggatgaac cgtattgaat tggtaaacgt gcaatggcat cagtattatc
    64201 actagcccag acttgtggga aatagcgtat cataccaaga tcatttcgtc caccaccacc
    64261 agagcaggac tcaaagagaa tatggctgtg cttctctgtc agataagaaa cgagttcgta
    64321 aagtcccagc atgtactgat gagattgcat ctgtgtctct agataagtta atccattccc
    64381 tagcttagtg atattgcggt tcatatccca tttaatgtaa tcaatctcat gataagatag
    64441 gagttgatct aagacacttt tcaagtattc tactacctga ggattggcaa gattaagtac
    64501 taattgattc cgagaataag tatgctcata atcaggaacc tgaatagccc agtcaggatg
    64561 ttgacgatac aaatcactat ctacagaaat catttcgggt tctaaccaaa gtccaaactg
    64621 caaacctctt tcatggatag ctgaaatcag actttctaga cttccaccca gtttttcctc
    64681 attaacaacc caatcaccta aagcacgatt atcatcaaaa cgattgccaa accaaccatc
    64741 atctaataca aaaagttcaa tgccaacttt cttagcttca tctgctaact ctaacagttt
    64801 ttctctctga aagtcaaagt aagtagcttc ccagttattg attagaattg gacgttcttt
    64861 tttagaaaat tcacttagag taatgtgctt cagtacaaaa ttctgacttt catgactaat
    64921 accagttaat ccctgatctg aatgagtcac taaagctacc ggtgtttcaa agtattcctc
    64981 aggggctaac ttccaagaaa agttttctgg attaatgcca atagccaccc gaacttcatt
    65041 caattgattt ttttgaacaa aagcttcaaa gttgccacta tacattagtt gaatagcaaa
    65101 cacattccca gcatcctctg tgactccttg ttcgcatagt agaagagctg gtgtttgagc
    65161 atgaccagaa gcacctcggt ttgaactaat cgaaaagatt ccttgttcta cctgttgacg
    65221 tctaacagtc ttttcacgag cataagcacc ctgcagagtt actatttcgt aatctgcagc
    65281 tggaaaatca gccataaaag aaaaatcttt atggatgaca acttcctgat tactattatt
    65341 atctaattta ctgtagctag caatagtcgc atcattatta aaagtagtat aatacaaagt
    65401 cagactaagt tgagccttag aatcttctaa cattaagaca agagtctctg tatcgtccat
    65461 gctatgtgga gaaggtaagc cctgtggacc attctgacct tttaaaatct ttgcttctac
    65521 aaatcgaaag tctgttactt cagttacact atgctgaacc tgtatagttg gtttcctaaa
    65581 atctcctaag ccatgttgtc caaaaatctg tcgctgagta tctaaactaa aggttcgatt
    65641 agtagccgtt ggatttcctg aaaaggcatg gtctcgttca taaacactat tggaaccttt
    65701 atagttctta atagtctttc ctaaatgttt caaaagtaag tagccatttc gattttcaat
    65761 aatcaaactt agatttttac tctcaacata aaatagatta ttctctatcc taactcccat
    65821 ttacttcacc tcatcacttt attgattata ttttatcacc tgaaatcgct ttccaaaata
    65881 gaaaaatgtc tcaagaatat ggtaaaatgt taggtaggag gtagcacatg ctagtttttt
    65941 cagaatacca gactggaaca attgaccttg ccctaagctt ttatggatat gaggaatgca
    66001 cacctaatta ctcttttggt ccagccattc gtgatacata cgtcctacat tacattagta
    66061 aaggacaagg aaaatttcat tacaagggta aaattgttga tttaaaagaa ggagatttct
    66121 ttctattaaa accagaggaa ctaacctttt atcaagcaga tagtaaagaa ccttgggcct
    66181 actactggtt aggaatcact ggagggaaat cccctgatta ttttgctctt tctcaaattt
    66241 ctgatcaatc ctatctcatc caatctgaaa cttgtcatac ccagactact gcaaaactca
    66301 tctcagacat tgtccgcttc gctcagatta caaaatcaag tgaattagct caactccata
    66361 tcatgggaca acttcatgaa ctgatgtttc atctgggaac tattgctccc aatcagaaaa
    66421 aaaagaatat ttcatcaacc caccaactct atcttgaatg caaacgatta attgatagcc
    66481 actatcctca atcacttaca attcaagatt tagcaaaaga actatccgtt cacagaagct
    66541 acttatcaag cgtattcaaa gaatttaata ccttatcacc caaagaatac ctactctacg
    66601 ttcgaatgca ccgagctaga caacttctcg aaaataccca agagtccatc aaggtaattg
    66661 catactcggt aggtttttca gatccactcc atttttcgaa agcttataaa caatacttta
    66721 atcagtctcc aagtcataca agaaaagaat actctcaata ccaactagtg agaaaggcaa
    66781 cattatgaaa tcctaccaag ctgtctacca aatcctatct aaagaaaccg actatatcag
    66841 cggagaaaaa atcgcagaaa aactatccct aagccgaaca tcaatttgga aagctatcaa
    66901 gcgactagaa caagaaggca ttgaaattaa tagtatcaaa aatagaggat ataaactaat
    66961 gaatggtgac cttattcttc cagagattct agaagaaaat cttccaatta aagtcagctt
    67021 taaacccgaa acaaaatcaa cacaactaga tgcaaaagaa gcaattgatt taggccatga
    67081 agcaaatact ctctatctag cttcctatca aacagcaggc cgaggccgtt ttcaacgttc
    67141 cttctactca ccacaaggtg gaatttatat gacactccat cttaaaccaa atctccccta
    67201 tgacaaatta ccatcctaca cactacttgt agctggagct gtctacaaag ccattaagaa
    67261 cctaacttta atagatgtcg atataaaatg ggtcaatgat atctatctaa acaatcataa
    67321 aattggagga atccttactg aagcaatgac ctctgtagaa actggcttag tcacagatat
    67381 cattattgga gtaggtatca atttcactat taaagacttc cctcaggaat taaaagaaaa
    67441 agctgccagc ttatttaaag ctacagctcc tataacaagg aatgaattga tcatagaaat
    67501 ctggcgtgct ttcttcgaaa caccagcaga agagctatta tacctataca aaaaacagtc
    67561 attcattcta ggaaaagaag tcactttcac actagagcaa aaagactaca agggacttgc
    67621 taaagacatc tcagaaaatg gaaaactttt agttcaatgt gataacggaa aagaaatctg
    67681 gctaaatagt ggcgaaattt ctctcaatag ttggaagtaa aataacacaa ttataatata
    67741 aacgatataa aaataacttc agattagtaa ttcaattaag ttttacggat ctgaagtttt
    67801 attgtctcta aaaacaaaaa agagagttac aaactctcat taaaacggag aataagggat
    67861 tcgaaccctt gcgccagtta cccgacctaa cgatttagca aaccgtcctc ttcagcctct
    67921 tgagtaattc tccaattaat gggcacgagt ggactcgaac caccgacctc acgcttatca
    67981 ggcgtgcgct ctaaccacct gagctacgcg cccaagttaa aaaacttggt aatttgaaca
    68041 aagttcaaag cgggtgacga gaatcgaact cgcgacaaca gcttggaagg ctgtagtttt
    68101 accactaaac tacacccgca taaatactat caataaaatg gcgcgagacg gaatcgaacc
    68161 gccgacacat ggagcttcaa tccattgctc taccaactga gctaccgagc cttattgcgg
    68221 gagcaggatt tgaacctacg accttcgggt tatgagcccg acgagctacc tagctgctcc
    68281 atcccgcgtt aatataaaag gaggatgtgg gattcgaacc cacgcacgct tttacacgcc
    68341 tgacggtttt caagaccgtt cccttcagcc ggacttgggt aatcctccaa tattcaaatg
    68401 gaccttgtag gacttgaacc tacgaccact cggttatgag ccgagagctc taaccagctg
    68461 agctaaaggt ccgacaagat cattatagcg gcgaagggga tcgaaccccc gacctcccgg
    68521 gtatgaaccg gacgctctag ccagctgagc tacaccgcca tgaatcggga agacaggatt
    68581 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
    68641 ttaaaaagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
    68701 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
    68761 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
    68821 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
    68881 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
    68941 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
    69001 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
    69061 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
    69121 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
    69181 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
    69241 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
    69301 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcccta
//
LOCUS       DAVIME010000004        67379 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVIME010000004 DAVIME010000000
VERSION     DAVIME010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.004"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     regulatory      complement(75..163)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(372..1001)
                     /locus_tag="VV588_000284"
     CDS             complement(372..1001)
                     /locus_tag="VV588_000284"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU7082689.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(1003..1785)
                     /gene="thiM"
                     /locus_tag="VV588_000285"
     CDS             complement(1003..1785)
                     /gene="thiM"
                     /locus_tag="VV588_000285"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU7082690.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(2028..2696)
                     /locus_tag="VV588_000286"
     CDS             complement(2028..2696)
                     /locus_tag="VV588_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU7082691.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(2911..2999)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3253..4389)
                     /gene="lctO"
                     /locus_tag="VV588_000287"
     CDS             complement(3253..4389)
                     /gene="lctO"
                     /locus_tag="VV588_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU7082692.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(5014..6504)
                     /gene="lysS"
                     /locus_tag="VV588_000288"
     CDS             complement(5014..6504)
                     /gene="lysS"
                     /locus_tag="VV588_000288"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU7082693.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(6632..6778)
                     /locus_tag="VV588_000289"
     CDS             complement(6632..6778)
                     /locus_tag="VV588_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU7082694.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            6811..7728
                     /locus_tag="VV588_000290"
     CDS             6811..7728
                     /locus_tag="VV588_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEU7082695.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFG
                     LARNFNINISGETSAIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFW
                     IYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            7729..8487
                     /locus_tag="VV588_000291"
     CDS             7729..8487
                     /locus_tag="VV588_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU7082696.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGASGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRTLLMHPE
                     IILFDEVTASLDSEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAHAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            8499..9371
                     /locus_tag="VV588_000292"
     CDS             8499..9371
                     /locus_tag="VV588_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7082697.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLARKTSSTRPMKKHFTQPTVTLLK
                     QMTWLLKVEKLISH"
     gene            complement(9451..10098)
                     /locus_tag="VV588_000293"
     CDS             complement(9451..10098)
                     /locus_tag="VV588_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082698.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(10095..10793)
                     /locus_tag="VV588_000294"
     CDS             complement(10095..10793)
                     /locus_tag="VV588_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082699.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(10803..11555)
                     /locus_tag="VV588_000295"
     CDS             complement(10803..11555)
                     /locus_tag="VV588_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082700.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(11555..12319)
                     /locus_tag="VV588_000296"
     CDS             complement(11555..12319)
                     /locus_tag="VV588_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082701.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMVVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(12415..12818)
                     /locus_tag="VV588_000297"
                     /pseudo
     CDS             complement(12415..12818)
                     /locus_tag="VV588_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12998..13630)
                     /locus_tag="VV588_000298"
     CDS             complement(12998..13630)
                     /locus_tag="VV588_000298"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU7082702.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(13664..14365)
                     /gene="pyrF"
                     /locus_tag="VV588_000299"
     CDS             complement(13664..14365)
                     /gene="pyrF"
                     /locus_tag="VV588_000299"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU7082703.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            14686..14778
                     /locus_tag="VV588_000300"
                     /pseudo
     CDS             14686..14778
                     /locus_tag="VV588_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(15100..15813)
                     /locus_tag="VV588_000301"
     CDS             complement(15100..15813)
                     /locus_tag="VV588_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082704.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFCKYLMETQG
                     KVNDQQELVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(15806..16645)
                     /locus_tag="VV588_000302"
     CDS             complement(15806..16645)
                     /locus_tag="VV588_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082705.1"
                     /translation="MSMIEVSHLSKSFGDKIALNNISFTVKEGQIFGFLGPSGSGKTT
                     TINILTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSK
                     FYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSG
                     LDPTTSRTIHELILELKTAGTTIFLTTHDMNEASLLCDYVALLNKGKLVEQGAPSELI
                     QRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGK
                     LNA"
     gene            complement(17121..17996)
                     /locus_tag="VV588_000303"
     CDS             complement(17121..17996)
                     /locus_tag="VV588_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEU7082706.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSEKIHKYNSDVQVVPISI
                     KVSSLEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NETLIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFYLLLGSSLL"
     gene            complement(18191..18988)
                     /locus_tag="VV588_000304"
     CDS             complement(18191..18988)
                     /locus_tag="VV588_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HEU7082707.1"
                     /translation="MGLIDSMKSRKKINIFKISWDFNITLSEKLNYKRFNKNFEKILF
                     GIFPLALILQCFIMYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIAN
                     NYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLVL
                     LFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIAF
                     VIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMIGRTKYVLRK"
     gene            complement(19779..20978)
                     /gene="divIB"
                     /locus_tag="VV588_000305"
     CDS             complement(19779..20978)
                     /gene="divIB"
                     /locus_tag="VV588_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU7082708.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            complement(20988..22046)
                     /locus_tag="VV588_000306"
     CDS             complement(20988..22046)
                     /locus_tag="VV588_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU7082709.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(22050..23402)
                     /locus_tag="VV588_000307"
     CDS             complement(22050..23402)
                     /locus_tag="VV588_000307"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU7082710.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIATD
                     KNTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(23506..24147)
                     /locus_tag="VV588_000308"
     CDS             complement(23506..24147)
                     /locus_tag="VV588_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082711.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(24149..26170)
                     /locus_tag="VV588_000309"
     CDS             complement(24149..26170)
                     /locus_tag="VV588_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU7082712.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(26241..26540)
                     /locus_tag="VV588_000310"
                     /pseudo
     CDS             complement(26241..26540)
                     /locus_tag="VV588_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(26904..27158)
                     /locus_tag="VV588_000311"
     CDS             complement(26904..27158)
                     /locus_tag="VV588_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU7082713.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(27178..29019)
                     /gene="typA"
                     /locus_tag="VV588_000312"
     CDS             complement(27178..29019)
                     /gene="typA"
                     /locus_tag="VV588_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU7082714.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            29181..29906
                     /locus_tag="VV588_000313"
     CDS             29181..29906
                     /locus_tag="VV588_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU7082715.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(29946..30173)
                     /locus_tag="VV588_000314"
     CDS             complement(29946..30173)
                     /locus_tag="VV588_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082716.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLEYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(30262..30642)
                     /locus_tag="VV588_000315"
     CDS             complement(30262..30642)
                     /locus_tag="VV588_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU7082717.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(30642..30911)
                     /locus_tag="VV588_000316"
     CDS             complement(30642..30911)
                     /locus_tag="VV588_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU7082718.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            30975..31883
                     /locus_tag="VV588_000317"
     CDS             30975..31883
                     /locus_tag="VV588_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU7082719.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLSHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(31937..32692)
                     /locus_tag="VV588_000318"
     CDS             complement(31937..32692)
                     /locus_tag="VV588_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU7082720.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(32713..33642)
                     /locus_tag="VV588_000319"
     CDS             complement(32713..33642)
                     /locus_tag="VV588_000319"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU7082721.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTVRPRKISKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTNASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(33657..34280)
                     /locus_tag="VV588_000320"
     CDS             complement(33657..34280)
                     /locus_tag="VV588_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU7082722.1"
                     /translation="MTDIKALALKYGGYTSLDKVYLVQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     DSDGLGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(34273..35511)
                     /gene="hflX"
                     /locus_tag="VV588_000321"
     CDS             complement(34273..35511)
                     /gene="hflX"
                     /locus_tag="VV588_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU7082723.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDS
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(35504..36388)
                     /gene="miaA"
                     /locus_tag="VV588_000322"
     CDS             complement(35504..36388)
                     /gene="miaA"
                     /locus_tag="VV588_000322"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU7082724.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVLHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHFVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            36509..36679
                     /locus_tag="VV588_000323"
     CDS             36509..36679
                     /locus_tag="VV588_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU7082725.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(36727..37566)
                     /locus_tag="VV588_000324"
     CDS             complement(36727..37566)
                     /locus_tag="VV588_000324"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU7082726.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(37663..38622)
                     /locus_tag="VV588_000325"
     CDS             complement(37663..38622)
                     /locus_tag="VV588_000325"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU7082727.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTVGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(38749..39747)
                     /locus_tag="VV588_000326"
     CDS             complement(38749..39747)
                     /locus_tag="VV588_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU7082728.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLTSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(39797..40414)
                     /locus_tag="VV588_000327"
     CDS             complement(39797..40414)
                     /locus_tag="VV588_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU7082729.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(40415..42136)
                     /gene="pabB"
                     /locus_tag="VV588_000328"
     CDS             complement(40415..42136)
                     /gene="pabB"
                     /locus_tag="VV588_000328"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU7082730.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(42197..47908)
                     /locus_tag="VV588_000329"
     CDS             complement(42197..47908)
                     /locus_tag="VV588_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU7082731.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVNPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TVNQSIEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTAPVEPEKQPEVPE
                     EEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLET
                     AKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTKVKEHYSDRSWQN
                     LQTEVTKAEKVAANTDAKQSEVNEAVEKLTATIEKLVELSEKPILTLTSTDKKILERE
                     AVAKYTLENQNKTKIKSITAELKKGEEVINTVVLTDDKVTTETISAAFKNLEYYKEYT
                     LSTTMIYDRGNGEETETLENQNIQLDLKKVELKNIKRTDLIKYENGKETNESLITTIP
                     DDKSNYYLKITSNNQKTTLLAVKNIEETTVNGTHVYKVTAIADNLVSRTADNKFEEEY
                     VHYIEKPKVHEDNVYYNFKELVEAIQNDPSKEYRLGQSMSARNVVPNGKSYITKEFTG
                     KLLSSEGKQFAITELEHPLFDKIKAGTVKNINFENIDINVSNQDNIATIANEINGTTR
                     IENIKATGTITARNNVAGFVNNIKENAALENVAFIGNINSVGNNSTVGGIAGSNYMGF
                     VNKAYVDANITAANASASMLVPLVTYMLNSYQYGTKSKVTNSVAKGTLDVKNTRFVGG
                     VVAKTWPWGVIKDIVTYAKVIKGEEVYGSNEINDGDARQFLSDIYRVNGASSGANNFT
                     NLQKIKQLTKEQADAKVATFNITADKLESELSPLAKLNEEKAYSSIQDYNAEYNQAYK
                     NLEKLIPFYNKDYIVYQGNKLNKEHPLNTKEVLSVTAMNNNEFITNLDEANKIIVHYA
                     DGTKDYFNLSSSSEGLSNVKEYTITDLGIKYTPNIVQKDNTTLVNDIKSILEPVDLQS
                     QTMYQHLNRLGDYRVNAIKDLYLEESFTAVKKNLTNLITKLVQNEEHQLNDSPAARQM
                     LRDKVEKNKAALLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGEKVSVLDRLIEIGS
                     KENNIKGSRTFDAFGEVLAKYTKSGNLDVFLNYNRQLFTNIDNMNDWFIDATKDHVYI
                     AERASEVEEIKNAKYRAYANLNVAQHRKMILPLLNITKSHMFIASNYNAIAIGSAEKL
                     GKKSLEDIKASVDYAADGYRNYYDFWYRLVPDNVKQYLLRDTVIPIWEGYNAPGGWVE
                     KYGRYNTDNVYTPLREFFGPIEKYYGYNGTGAYAALYDNPMDPRSDVSYVALNMIGDY
                     GISVYTHETTHINDRKIYLGGFGRREGTDAEAFAQGMLQLPVPGSGFNEYGSLGLNTV
                     FKKPNDGNQWYDTDPKSLTTRDDIDKYMRGYNDALMLVDHLEADAVINQNNKELNGAW
                     FKKIDKKFRDASQLNQWDEIRNLTTEEKDNLNITSIDSLIDQQLMTNRQIGNRVYKPE
                     VVSQYDQSPYVGVEMTAGIYGGNTSKGAPGAVSFKHNAFRLWGYYGYLNGFLGYTSNK
                     YKQQSTKDGESVLSDEYIIKKISNNTFNTIEEFKKAYFKEVKDKATKGLTTFEVNGSS
                     VSSYDDLLTLFKEAVKKDAETLKQEANGHKTVSMTNTVKLKEAVYKKLLQQTDSFKTS
                     IFR"
     gene            complement(47930..48493)
                     /locus_tag="VV588_000330"
     CDS             complement(47930..48493)
                     /locus_tag="VV588_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU7082732.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(48609..50300)
                     /locus_tag="VV588_000331"
     CDS             complement(48609..50300)
                     /locus_tag="VV588_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU7082733.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(50297..51034)
                     /locus_tag="VV588_000332"
     CDS             complement(50297..51034)
                     /locus_tag="VV588_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7082734.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(51302..52414)
                     /gene="msrB"
                     /locus_tag="VV588_000333"
     CDS             complement(51302..52414)
                     /gene="msrB"
                     /locus_tag="VV588_000333"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU7082735.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(52425..52991)
                     /locus_tag="VV588_000334"
     CDS             complement(52425..52991)
                     /locus_tag="VV588_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU7082736.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(53011..53721)
                     /gene="ccdA2"
                     /locus_tag="VV588_000335"
     CDS             complement(53011..53721)
                     /gene="ccdA2"
                     /locus_tag="VV588_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU7082737.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            complement(53932..54792)
                     /locus_tag="VV588_000336"
     CDS             complement(53932..54792)
                     /locus_tag="VV588_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU7082738.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSINFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQFLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGVLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDQVFKKD"
     gene            complement(54971..57025)
                     /locus_tag="VV588_000337"
     CDS             complement(54971..57025)
                     /locus_tag="VV588_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU7082739.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLILPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(57037..57291)
                     /locus_tag="VV588_000338"
     CDS             complement(57037..57291)
                     /locus_tag="VV588_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082740.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(57284..57841)
                     /locus_tag="VV588_000339"
     CDS             complement(57284..57841)
                     /locus_tag="VV588_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU7082741.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(57825..58781)
                     /locus_tag="VV588_000340"
                     /pseudo
     CDS             complement(57825..58781)
                     /locus_tag="VV588_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            58873..59232
                     /locus_tag="VV588_000341"
     CDS             58873..59232
                     /locus_tag="VV588_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU7082742.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKLSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            59444..60298
                     /locus_tag="VV588_000342"
                     /pseudo
     CDS             59444..60298
                     /locus_tag="VV588_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(60546..67232)
                     /locus_tag="VV588_000343"
     CDS             complement(60546..67232)
                     /locus_tag="VV588_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU7082743.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTANVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGKERIFT
                     VINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEADQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
BASE COUNT        20062 a        14481 c        11906 g        20930 t
ORIGIN      
        1 aaagaaaaaa ctctaattac agatacgaat tagagttcag cttacaagat tagacagttc
       61 ttttcgacat acgaaaaaaa catttcacat ttcccttcgc cagtcttaac tgtatcaggt
      121 tcaatgggta tcatctcagc ctaaagcacc ccaaatgcct ttattattta attatgtgat
      181 tattataaca cacattttat actagttcaa gaaattgaac tggaaataca gccttgcact
      241 cacaaagaca gcagatcttt cttttgcaaa aaacaaatga cctgtttgat gaattaacca
      301 ttcaagctga atctagacat agctttttaa aaaaggaaaa tcctacttac ttagaatcca
      361 aggatagata tctattgctc actcatttcc cgaacagttt tttctatatt ttttgcatac
      421 gatattgccg aaatgattga aacgccgtca acattggtct ttataatgtc tttaatatgt
      481 ttcgtctgta tcccaccaat tgcaactaaa ggcatttgtg gcaatagttt tctcatcaat
      541 tcaagacctt cataacctat agcaccacca gcatcatcct ttgactgggt atcaaataca
      601 ggaccaacac caacataatc tacatattca acttttgatt gttgaaattc ttcctcgttt
      661 tttatagaaa gaccaattat tttatctggc atcaattttc taatttcatc aacaccaata
      721 tcatcttgac ctacatgtac gccatcagcg tcaatttcca ttgccaaatc gatatcatca
      781 ttaacgataa acggcacatt gtatttttta caaagttctt taatttggat agctagctca
      841 agtttttcta agccttctaa agcaccctca cctttttctc gaaattgaaa taaggttata
      901 ccacctttta aggcttcctc aacgactgta tatagatttt ttccttggca agtagtcgtt
      961 ccacaaataa aatatagttt tagtaattct ttatgaaaca tcttacttca ctcttttgaa
     1021 ttcctttaca tcttcatctg taatctcgta taaggcattt ataaattcaa ctttaaatgt
     1081 cccaggaaga tgtccatttg gacgtttttc tgccatttct ccagcgatat tgtaaaccaa
     1141 cattgctgtt tctaatgatt tcaattcttg acctttttct agtccgataa agcttgctac
     1201 cactgcccct aataagcatc ctgtcccaat gactttcggc atcatagcac taccattatg
     1261 aatcgttacc acttctccat taacagcaat ggcatccact tcacctgtta ctactattgg
     1321 aatattgaac ttctcatttg ctgctagagc aatttcgtca atattatcta cgcccgcact
     1381 atctactcct ttagatgcca catctattcc tactaaagag gcaatctcgc cagcatttcc
     1441 tctaatcgct gctagtttat aattgttgat tagatcatct gctacttttt ttctatattc
     1501 tcctgctcca caggctacag gatctaaaac tgctgggaca ttatatttct ctgcaatttt
     1561 cagagcagct tggtataatt tccaattttc atctgtcaat gttcctatgt ttattaataa
     1621 accaccagca tactttaaca aatcctctaa atctgctgga aactcactca tggctggtga
     1681 ggcgcccagt gctactaatc catttgctgt gaaatttttt actacatcat tggttataca
     1741 aatgaccaat ggtgcttttt cttttaataa ttttaaactt gtcatattga aatccttcct
     1801 tttcacttta tacgatctac tgatttcgat ttatttctat ctttcgttaa gaattttttt
     1861 catttacatt gaatgattta tactcaatga aaatcaaaga gcaaactagg aggctaaccg
     1921 caggttgctc aaaacactgt tttgaggttg tggatagaac tgacgtggtt tgaagagatt
     1981 ttcgaagagt cttacctcat caaatttgta aatatcatga gccttctcta gacattgtaa
     2041 ccaatatcaa aaaaagctaa ttctaaagcg actgcttgat tccagcgttg ctgaagttct
     2101 gtcaaatctt ctcgattttt atcgacacga ttgagttcgt caaccagaaa ttgaacccac
     2161 tctgcaaaga aaggacctct gtggagattg atccattccg aatgaatata gacttcaggt
     2221 aaagccaaat ctttagaacc ccagtctaaa tagagacctt ctgcaatgac cagcatgacc
     2281 aaaagatggg catagtctga tgaagccacc gccgaataca ttagatcctg aaaggctttt
     2341 gttacagggt gcaaagtcac ttctagatag tcattctctg ctacttttaa ctctttaaaa
     2401 gccttttgga aataaccatc ttcatctgct tcaagaaagc ctagttgctt ggcaaaacga
     2461 agcttggatt caagtttatc tgcgtgagct acgcaggcac ccagcatgga taagaaggca
     2521 tcaaagaagt gataatcttg aatcagatag tcctttaaga ccttattctc aattgtcccc
     2581 gcaaaaagtt ccttaacaaa acgatgattg attgcagcct gccaatcctt ctgactgctt
     2641 tttaataatt ctccaacagt caaacctggc tgaaatgcat agtcttgtgt ttccatattt
     2701 acttctcctc tctttacttg ttagtaatta ataaaacacc aagaaatatc aagcaaaatc
     2761 gtaattccac ttgatccttt taaagcacat cgagagcatt tgcagagagc taactaaaca
     2821 agcctatcca gtttatataa acaaaaaact ccaattacaa tcaagaatta gagttgactt
     2881 acaagattag atcgttcatt tcgccatacg aaaaaacgtt tcacatttcc cttcgccagt
     2941 cttaactgta tcaggttcaa tgggtattat ctcagcctaa agcaccccaa atgtctctat
     3001 tatttaatta ctgaaccagt atagcaaaaa atgaaagccc tagcaagata tttgaccgaa
     3061 aaatatcttt atatataata tattgaaact agaatagtac acctctactt ctaaaacatt
     3121 gttagaaatc gatttgactg tcctgattga tttgtcctat tcttatttca ttttactata
     3181 gttttcgata gcaatttatt cttccaatac acgaagaaaa acctccacat tcagtggagg
     3241 caatctgttt tatcaataca attttaagtc acgagggtca actgggaagg ttgggttgta
     3301 tggattgtga cggagcttaa agtgtttgac atcttcaatg gtctgagctc cagacaattg
     3361 cataactgtc ttcaattccg cattcaagtg ttcaaagact tgacgcacac cgacactacc
     3421 accgagagcc aagccataaa taacagggcg accaatagct accaagtctg ctcctgaagc
     3481 caaggcttta aagacgtgtt gaccacgacg aacaccagag tcaaagacaa tcggcacacg
     3541 tctatcaact gcttctgcca cttcttgaag cgagtcaaag gcagctggtc caccgtcgat
     3601 ttgacgacca ccgtggttgg ttacccagat accagaagct cctgcagcaa gtgaacgttc
     3661 aacgtcctca cggcattgtg gtcccttgac atacacagga agaccagagt attcagcgat
     3721 aaattctaca tcgcgtggag acaagcgttg tttagctgat ttgtaaacaa agtccattga
     3781 tttaccagca ccttctggca ggtattcttc aacaatcggc atgccaactg ggaagacaaa
     3841 accattacgc ttatccactt cacgattccc ccctacagta gcatctgccg tcaagacaat
     3901 cgctttataa ccttcagcct tcacacggtc catgatgtgg cggttgatac cgtcatcctt
     3961 actaaagtaa aattggaacc aatggggtgt cccttgaagg gcttcagaaa tctctggaag
     4021 gtcaacagta gagtaagagc tggttgtata aagagaacca aactcatgca caccacgcgc
     4081 agtcgccact tccccctgtt catttgccaa tttatgagcc gcaacaggcg ccataatgat
     4141 tggtgaagat agtttttcac ctgcaaattc aatctctgta cttggatttt caacatcgca
     4201 aagtgtatga ggaacgatga gtttgtggtt aaaggcgcgg atattctctc ttaaagtgaa
     4261 agtatcttcc gccccactag cgatatagcc aaatgctgct ttaggaataa cttgttgcgc
     4321 cattggctcc aaatcatagg tattgatgaa gtctacatga ccttctgcat tgcttgtttt
     4381 gtatgacata aaatgccctc cttgattaag taagcgtttg ctttttacta cacaactata
     4441 ataactcttt tttcaatcat tttcaagagt tttgcttaaa aaccatctta ttttttcata
     4501 caatatacta gccctacttt ccttaaactc taaactttag tctatattaa gtgaatcgtt
     4561 gagatttttt gctgccaggc atttgaacta cttttttatt tgcggattct atctactaat
     4621 actataaaaa aacaagtgaa taagacacca gaacatcctc taataggacc tatggactta
     4681 tatcagtccc atatatactg tttaagcaag atactatcct agttgacgct aacttcctat
     4741 cccacttatt aattttttat ttatagtgaa tctgaacaaa tcaattgggg aatccaagtc
     4801 aatttctagt actttttgaa cagtttcagc gtactatcgt aaaatgaaat aaaacatgca
     4861 caaattgctt agggaattta aaccaatttc taacaatgtc ttagaaatca aagtgtacta
     4921 tttcaacttc aatatactac acttcatttt ctccttaaat tcagtctctt tttgaatcaa
     4981 aaaatcccct ggtaagagcc agaggataag aatttatttc attgttggga agagcaatac
     5041 atcacggata gttgttgtat cagtgaggag catgcagaga cggtcgatac cgattcccaa
     5101 accacctgtt ggtggcatac cgtattcaag agcttcaatg tagtcatagt cgattcctgt
     5161 cgcttcatca tcaccaagtt ctttggcttt agcttgggct tcaaaacggc taagttggtc
     5221 gattgggtcg ttcaactcag taaaggcatt accgtactcc ttagtcatga taaagagctc
     5281 gaaacggtca gtaaagcgtt ggtcttcagg atttttctta gcgagtggag atacagctac
     5341 tggatgtcca tagacaaagg ttggttggat taaagtttct tcaacaaact cttcaaagaa
     5401 ggcattgatg atgtgaccaa cctcagtgta gtgtttctca actggaactt tcttctcagc
     5461 agcgatagtt ttagcttctt ccaaagtcat gtcttgccag aaatcgacac cagtaatttc
     5521 tctgatagca tccaccatat gaacacgctt aaatggttcg ttaatcttga tttcagtacc
     5581 ttggtagttg actgggccat cgcctttgac tgatttagca gcatgttgga taatgccttc
     5641 cgtcaagtcc atgatatctt ggaagtctgc ataagcttgg taaacttcga tagaagtgaa
     5701 ctcagggtta tgagtagcgt ccattccttc gttacggaag atacggccaa tttcatagac
     5761 acgttccata ccacccacaa taaggcgttt taagtgaagc tcagtcgcga tacgaagcac
     5821 catgtcaatg ttttgggcat tgtggtgggt gataaatgga cgggcagcag caccaccggc
     5881 ttcattatga agaacaggtg tttccacttc aaggaatcct ttttggtcaa ggtaacgacg
     5941 gatttcagag atgatttttg aacgagtgac aaagcgttca aagctttcac gattagaaat
     6001 caagtcaagg taacgtttac ggtaaattgt ttcaacgtct gtcaaaccat ggaatttctc
     6061 aggaagagga cgaagagcct tagacaagtg tgtgatgtgg gttgccttga tagagagttc
     6121 tcccatatcc gtacgcatca cttcaccttc gacaccaagg aagtcaccaa ggtctgcttt
     6181 tttgaagatt tcgtagtttt cttcaccgac agcatcctta cgaacataga tctgaatctg
     6241 gccttcgcgg tcttgaaggt gggcaaaacc aacttttcct ttaccacgtt tggttaccaa
     6301 gcgtcctgcg atagtagctg tttcgttttt atcgtgtaat tgttctttat cgaggttggc
     6361 atatttatct tttaattctt gtgaatttgc agtacgttca aaacgttttc cgaaaggatc
     6421 gattccttgt tcgcggagcg cagccatttt ttcacggcga acgatctgct ggtcatttag
     6481 ttcttccata tgttctgtag acatgggatc ctcctagttt tactcaaaat tgaatacgat
     6541 gagtcatttt ttgcgatact cccattttat cataaataag caagaaattc acggataatc
     6601 tttaaaaact aaaaagaacc tgacgctaaa atcactggaa agaagtgaaa gtatcttccg
     6661 ccccactagc gatatagcca aatgctgctt taggaataac ttgttgcgcc attggctcca
     6721 aatcataggt attgatgaaa tctacatgac cttctgcatt gcttgttttg tatgacataa
     6781 aatgcactcc ttgataagta agcgtttact ttgtatattg cagtttgggg aagtttggga
     6841 tcctttctgc tcggtttaat cgttagtatc atccgacatt atcgaatccc tgttttggcg
     6901 caagtagcga cagcctacat tgaattgtca cgtaatacgc cccttttgat tcaactcttc
     6961 tttctctact tcggtcttcc ccgaatcggg attgtcctat cttcagaagt ctgtgcaacg
     7021 cttgggcttg tctttttagg aggctccgcc atgcaggatt cgggaatcca agtactcttt
     7081 caaggaaata atctcctgag aatcttacag ggattgggcg ttacgattgg gatatccatc
     7141 ctgtctgtcc tcttatccat gatgttcgga acagtcatgg gaatcatcat gacctcccat
     7201 tctagaatca tacgattttt aacacgattg tatctggact ttacccgtat catgccccag
     7261 ctggtgctac tcttcatcgt ttactttggc ttggctcgaa actttaatat caatatctca
     7321 ggtgagactt cagctattat cgtttttacc ctctggggaa cagctgaaat gggagacttg
     7381 gtacgtggag ctatcacttc tctccctaaa catcagtttg aaagtggaca agcactcggc
     7441 ttgactaatg ttcaacttta ctaccacatc atcatcccac aagtcttgag aagactgcta
     7501 ccgcaggcta tcaatcttgt cactcggatg attaaaacca cttcattagt tgttttgatt
     7561 ggggttgtgg aagtgaccaa agttggacaa caaatcatcg atagcaatcg cctgaccatc
     7621 ccaactgctt cattttggat ttatggaacc attctagtct tatatttcgc agtttgctac
     7681 cctatttcca aactatccac tcacttagaa aaacattgga gaaactaaat gtctgaaact
     7741 atcttagaaa tcaaggaact aaaaaaatcc ttcggagaca atcccatcct ccaaggactt
     7801 tctctagaaa ttaaaaaagg ggaagttgtt gtcatcctag gggcatctgg ttgtgggaaa
     7861 agtaccctcc ttcgttgcct caacggctta gaaagtattc aaggtggaga tatttttctg
     7921 gatggtcagt ctatcgttga aaataaaaaa gattttcacc tagttcgcca aaagattggc
     7981 atggtctttc aaagttatga actctttccc catctggatg tcttacaaaa cctcatccta
     8041 ggccctatca aaactcaagg aagggacaag aaagaagtaa cggaagaagc tttgcaatta
     8101 ctagatcgtg tcggtttgct ggataaacaa catagctttg cccgtcaatt atctggtgga
     8161 cagaagcaac gtgttgcaat tgtccgtacc ctcctaatgc atccagaaat catccttttt
     8221 gacgaggtga ctgcttcgct ggattcagaa atggtgcgtg aggtgctgga acttatcaat
     8281 gatttggccc aagaaggccg taccatgatt ttagtaaccc acgaaatgca gtttgcccaa
     8341 gccattgctg accggattat cttcctcgac caagggaaaa tcgctgaaga aggaacagct
     8401 catgccttct ttaccaatcc gcaaaccaaa cgagcccagg aatttttaaa cgtctttgac
     8461 tttagccaat ttggctcata tctataaagg agattcttat gaaactattc aaaccactct
     8521 taactgtttt agcacttgcc tttgccctta tctttatcac tgcttgtagc tcaggtggaa
     8581 acgctggttc atcctctgga aaaacaactg ccaaagctcg cactatcgat gaaatcaaaa
     8641 aaagcggtga actgcgaatc gccgtgtttg gagataaaaa accgtttggc tacgttgaca
     8701 atgatggttc ttaccaaggc tacgatattg aactagggaa ccaactagct caagaccttg
     8761 gtgtcaaggt taaatacatt tcagtcgatg ctgccaaccg tgcggaatac ttgatttcaa
     8821 acaaggtaga tattactctt gctaacttta cagtaactga cgaacgtaag aaacaagttg
     8881 attttgccct tccatatatg aaagtttctc tgggtgtcgt atcacctaag actggtctca
     8941 ttacagacgt caaacaactt gaaggtaaaa ccttaattgt cacaaaagga acgactgctg
     9001 agacttattt tgaaaagaat catccagaaa tcaaactcca aaaatacgac caatacagtg
     9061 actcttacca agctcttctt gacggacgtg gagatgcctt ttcaactgac aatacggaag
     9121 ttctagcttg ggcgcttgaa aataaaggat ttgaagtagg aattacttcc ctcggtgatc
     9181 ccgataccat tgcggcagca gttcaaaaag gcaaccaaga attgctagac ttcatcaata
     9241 aagatattga aaaattagca aggaaaactt cttccacaag gcctatgaaa aaacacttca
     9301 cccaacccac ggtgacactg ctaaagcaga tgacctggtt gttgaaggtg gaaaagttga
     9361 ttagtcatta actcttaaaa ggaactggat tttaagctcc aatccctttt taagatttta
     9421 cctataacat cctgagtcta tctaagatgt tcaatctgaa cacagtgtac atactttatc
     9481 ttctattgca tatactttat cacataagat acgaatatcc tcttcactat gactagcaat
     9541 caaaattgtt gtcccttttt cactagagag ctttctaaac aatgttctca tattttctac
     9601 acttgattta tccaaggcat tcataggttc atctagtaaa agaatagagg gattctccat
     9661 aattgcttga gcaatcccta gctttttcct catacctagc gaataagttt taactttctg
     9721 gtctttttgc tcatatagac caactatttt cagtgtatca ttgatttcct gattaccaac
     9781 tactcctcgt atgcttgcca aatattgtaa attcttaaag ccactataat aatttataaa
     9841 accaggttct tcaatcaaag ctcccaaatt agctggaatt tttctctcag gaacaatatt
     9901 ttccccattg attaacactt ctccataaga cggactatat aaaccagcta ttaatttaaa
     9961 caatacactt ttacctgagc cattcgcacc agtaattcct ataatttccc cctgtttaca
    10021 actaaaatta aggttttgaa aaacacatgt tttttttaat ttcaactcaa tattttttaa
    10081 tgtaattatt tcattcattc tataaacctc ctcttttgac gagtgaaata gaaaatgctt
    10141 ttaaaaagaa agactaaaaa tagcaactga agaaataaat ctcgtcctat atctccattc
    10201 cctcgattca aaatataaaa tagataatta gttcgatttc ctacaaatag accaccaaac
    10261 acaatcatga gtaaaaagaa actaacgcaa gcaaagttca tttgtacatt cgctcctagt
    10321 gcgtataaca taaagcaaag caaggatagc acacaagcat tcaaagaatc aactataaac
    10381 aaaactccta tatcccagtt tgctaactgt aacataaatt gaatcactag aacttttacc
    10441 atgattaaaa tgagtccata aagaaaacag gtccaaatct gatacctaat ccagagctta
    10501 atagaagaaa atcgaatcac ttccataaag aaatcggatg ctcttctacg atatacaact
    10561 gctagaaaaa atgtatgaat aataaaccaa tgaagcaacc atatagataa gactaaaaaa
    10621 gagttttgac tcagattagg cccttttaaa atttctataa caagtctatc atttccttct
    10681 aaccaatacc ataatcctaa acaaatcaat atccaaaaaa gaacataacc ccaaaagtac
    10741 ttggtataga ttatctgatt caacctccac atgtgactac ttaactttcc catttccaac
    10801 ttttacactc tcctccagtt tctatgaaca gaaaatacag tcaatggaat tatgatagat
    10861 agtaatgtaa gccaataaat caatgcatac ggattggaat ttaccatata ctgaaaaatt
    10921 ggcaataatc caattatccc attgttcaac tgataaatcc agaataagga ttctacaaat
    10981 aaaaaagtaa acagaaatac taagctcatg tttgattttt taaaccaaga aaaactgcta
    11041 atagtaagta aggataaaaa gaaatagtat gctatataag agaaaaaaaa tcctataaag
    11101 aaactagcat tgtttgcaat acttatacca taaaattctc ttaaaaaatc aacctccttt
    11161 atctccaaag agaagctaaa accattacta aatgcaatta gaaaaatcaa taaaaataaa
    11221 gtcgccgtcc aaatccccgt actaagagct gctaatttga aactaaaact ggtaaagtgc
    11281 ttaattgatt tcagacgaat gcgacactcc aacctattaa aatagttatt catcaaataa
    11341 aaaaagaaca atatatatgt gaacggaaag caatatactc cagtcgtcat atcttgaagt
    11401 aaaactaaaa tccattctaa tacatttgga tggattgaat attggcgaca gcgcaataaa
    11461 tatactgtac tagataaaac acaggatagc agtaatataa aataaaccaa tactgctaag
    11521 aaatcttttt tataaaattg aacaaattgt ttcattatac atagtcctct gaatgtagaa
    11581 aaaatgtacc ataaacaacc aaacaactaa caaataaaat aaaagcaaga tgcccactaa
    11641 ctaaggaaag actgatatct ttctgatatc ccaaagctag cgttgtcaca ggttctaagt
    11701 aagatagccc taaaatagcc cataaaatac caccaaccac catataggca actgggatga
    11761 aaatagctcc taattttttc ttcactagca aagcactagc tagtccaaaa atagagaaca
    11821 cagcgcccca aactccatac cagagagtcg tcacaagact atagagaaac tgattagaat
    11881 caaataattc ttttaaggca ccactataat ctccaatata aatttcctga taaggagtca
    11941 ctaaaagatt aattcctaat aataataaat aggggagaaa aaagactaga aaagaagaaa
    12001 taattgcagt actacctaca atagctagat acctcttttt agaaattcgg cacaattgtg
    12061 ctgttagaaa atgactctca gcatcctcta ttatctgact agaatagggc agtgtacaga
    12121 taagtgcagc tactaggcta atcggtgaaa atcctcgaat agaagaagcg gcaaaaaaaa
    12181 tcgataaacc ttcaatttta taaataccat tgaaagcaag gaaatttcct aaactcatgc
    12241 aaagaagggt caaaaataaa gacatataaa accgaggtga ttgaacgact cgtacaagat
    12301 tacaaatgaa aaattccatc cttactcctc cttataataa aaatagggtg tagcattctt
    12361 ttttcatgct acacccacaa tcaaccatct ttaaggctta ctctgacaag taagttaata
    12421 agaatctgga ctccaagaac ctgaagtatg aattcttaca tgatttccaa attgtggcgc
    12481 catagctaat ctagtaccag aaccaatata attgtcacca cctccattat agtacatgac
    12541 aatcctagag ccagacccca atgaatatac cggggtaata tctgacccac tataggcgct
    12601 acgaatagag gtatttaacc ttttaccgcc accagtgctg tcactattat taattccagc
    12661 agaggcgttt tctttctcaa gctcactagt tgtatccgaa ccccaacgcg gcaacgttaa
    12721 atcataattt ccaatctgtc tagctaaaac tgtagggaga aacaaactag atgcaattgt
    12781 aactacgcaa aaaaggaata tatttttctt cttttcatga catcgtcctc ttaagaagtg
    12841 ataaacaaga tagttgattg atcaatttga tacatattac attttcatta tatcaataaa
    12901 agaaagcgtt gtcaattatt ttatttaaaa tattatcata ttttaaataa aatggtaaaa
    12961 gagactcggt agcctcgtct ctctttatct tactgaccta accttcttgc caattttctt
    13021 ggtcttcttt aaagcgtttt agaagatcaa ggccctctgg cgtgatgtaa ccttcttctt
    13081 gggctagatg gataagctcg ctatagtttg aaagcgtcac aagtttaaca ccagcatctg
    13141 caaagttctt atctgctttt ggcaattggt agctgaaaat cgctacaact ccaagtacat
    13201 ctgctccttc tcgcttggct gctgctacag cttcaagaac tgaaccaccc gttgaaataa
    13261 ggtcttcaac cactaccatt ttttgacctt gagctacgcg accttcgatt tgattaccag
    13321 ctccgtggtc ttttggtttg ctacggatgt aggcaaaagg caagtccatc ttatcagcaa
    13381 taatggctcc gtgtggaatc cctgctgttg cagttcctgc aatcacttct acttcaggaa
    13441 aggcttcttt gatagcttcc acaaaaccat tttcaattag ggtacgagtt tctggatagg
    13501 ctagtgtcac acgattatca gtgtaaatcg gtgacttgat accagacgcc caagtgaagg
    13561 gttcctctgg tttgaggtaa acggcttgga ttttcaagag gtggctagcg atatctttag
    13621 caagtgtcat ggtattctcc ttttattttt ctaatctagt tctttaattc cagtcctgtg
    13681 tccattcatc cttgatggca tgataagctg caacaggatc ctcagcttgg gtaatgggac
    13741 gtcccactac gatatagtca ctaccaattt gataagcatc tgctggcgtc atgacgcgtt
    13801 tttggtctcc aacagcagct ccctgtgggc gaatccctgg tgtcagacag ataaaatctg
    13861 gattggtggc ctgcttgata agttgaactt cctgtgccga gcaaacgaca ccatccaagc
    13921 ctgcttcagc tgtcttcttg gcatagtgga tcacagactc ttgtaggctt gtttggatat
    13981 tttgaaactc ctgcatctgg gcttctgatg ttgatgtcag ctgcgttaca gcgatcaatt
    14041 ttgcttgact tccaagacct tcacgcgcag ccttcatcat ctctacacca ccagccgcat
    14101 gaacattggt catatcgaca ccaagctgag acaagacctt catggctgac ttgactgtat
    14161 taggaatgtc atgaagtttg agatccaaaa agacactatg acccaaacct tttaagtagg
    14221 acacaatctc aggccccgct gcgtaataaa gctccatccc taccttgaga taaaggcttt
    14281 cttctgctgg gaaaagagct aaaaattcct tgaccgcctc aaaactagga aaatcaagag
    14341 caatgattgg acgatgttct cgcataggtt tctcctttta cctttactag tgagagagtc
    14401 tggccaacag aagccacgaa aaaaggaacc tgccaacagc aaggttccac gaaaaatggg
    14461 tagtctccac cctttcaccg tctaacctta gctgcctctc tggactgctt taaaggtttt
    14521 ctattattct attatttcta ctagcacttg tcaagtaaaa acatggtcac gtatgtgttg
    14581 actgctattg aacacctcac aagactcttt ccaaaagaat agttaaagac tttcactgag
    14641 gacagagaaa aagagtttgc ttgttaccct ttaattgaac aaatgggaat tctgttttat
    14701 tttgcggatg cctattcatc ttggcaaagg ggaagtaatg agaatgcgaa tggacttctt
    14761 cgtgagtatt ttcttaaacc gatttggcaa caattaccga aaaaatcctt aatggtgctt
    14821 tgctagctta ttaatcaccg ttcccaaaaa tacttggatt acaagacagg ttttgaagca
    14881 cttatagagg agatttaaaa atgttgcatt ttttattgca atttatcagt tatcttatca
    14941 cccaaaactt ctgcaattag tatgagcact attgttattt ttcttttttc gtacactcaa
    15001 atcaaaatat agcaataaga ctattctgta gaattgctgt caaaaagatc agttcatttt
    15061 tccttcccac ttgtgtttat aatcattaaa ataactcaat taagaaattt tctttttcct
    15121 aatagttatc gtaattaaag ttaatagaag aacaatccaa ataagtagtg ttagattagg
    15181 aattagagtt tcattccatg aaaatccctc ccattttgtg aaaaacttag taaacagtcc
    15241 cataaaacta taatctgtta tcttcgcaac tgtcttatcc aaaccagata gcatcggtaa
    15301 gaaagcaact aaaatcatag caggaagact gataacctga gctactactt ggctcttcgc
    15361 ggttaaacct atcaataaat agaataaaat gatggataaa gaggttagaa gaacgattgt
    15421 aatataatta aaagtatgta caattgtaac tcctaaaata agaggagtag ttcccataat
    15481 cacaaaagtt agcaaaaaag gaagaaacat cgttgataaa atgtattcgg atcctttaac
    15541 accactcaac agaagagttt gtaaattgta cttttctttt tcttcagaca agataatagt
    15601 tataggactt ccaacagcca aagccaaaga aaaaggtaaa cacatcatca aaagaactaa
    15661 ttcctgttga tcgttgacct tcccctgtgt ttccataaga tatttacaaa aatatgtgaa
    15721 agcaaaaggc actaaaactt gcaataaaat actcttattg gaaaggataa tttgacaacg
    15781 caaccatacc aaagccagaa accgtttaag catttagctt tcctcctgtt aatgtgataa
    15841 aaatatcttc taaagtaggc tcacatgaat gaattgaaaa aatattttcc agatcagcct
    15901 gagatacctg ttctagtgat gtaaaatcaa aagttatctg attcccatta taatctgtaa
    15961 ccttaatctt tttatcttta ttatatcttt gaatgagttc agaaggagct ccttgctcaa
    16021 ctaatttccc tttatttaat aaggcaacat aatcacataa aagacttgct tcattcatat
    16081 catgagtcgt tagaaaaatc gttgtccctg ctgttttcaa ttctaaaatt aactcatgaa
    16141 ttgttcgaga agttgtggga tctagacctg aggtcggttc atccagaaag agtacagcgg
    16201 gtttgttgat aagagctcgt gctaaaagca ttcgttgcct cattccagtg gataattttc
    16261 ctgctaccat cttgcgacta tcatataatc ctactcgctt taacaaatta tcaacacgtg
    16321 atttactaat attataaaat ttactataaa aaagaagatt gttatacaga gacattttct
    16381 cataaaatcc acttgtatcg ctaaccaatc caattctctt taattcaccg cttgttaaat
    16441 tttgagattt ttgtcccaaa ataatagatt gtcctttatc ggcaaggaac tgcccagtca
    16501 gaatattaat cgttgtggtt tttccagaac cagatggtcc taaaaatcca aaaatctgac
    16561 cttctttaac agtgaagctt atattattta aagctatttt atcaccaaaa ctttttgata
    16621 aatggctaac ttcaatcata ctcattgcac ctcctttata ttctacattt ttacttaaca
    16681 tctatttact tagctttatc aaataaacgt cttaaaaaaa acaataacat taagcatata
    16741 accgttagca agattgtttc aatattattg ataatatgat acattctcaa gcagtataaa
    16801 ataattatat atatgcaaat gctcattata cctatttttt taaacatact aagcctcctt
    16861 gccaaataat aaagttatat aataactaag acacactata cctaacataa taaatatcca
    16921 cagcattaaa aatattatca tacaaataaa aatatccact ggtaactgaa taaatgttct
    16981 aaaattaaca agcaaaaata aaatctcaaa cgatgaaaaa agccatacta tattttccaa
    17041 tgatgtttga atatttttat tgtagtaagc ataatatata gcaaaaataa tacccaagaa
    17101 caatactatt aattgtgttt ctataacagt gaactgccca atagcagata aaaagctact
    17161 cctcctgata ataagcaaaa acaaactgaa cgaataaatg ttttcgctct aatattgtta
    17221 tctttcactt tattattttt tttacaaatt ggacattctc cgttttccag aacatatttt
    17281 tcttgactta gagcatgatt tctcatatta taaacgtaag cgttatctat tagggtttca
    17341 ttataacatc ccagaaatat tttaattatt aaattagtca ttatccctcc caaaatagca
    17401 ggcatctctg gtgtagtcgg ccactttgtc ttatcagata aagtgtactt atttatatct
    17461 ttgtttatat tccgacaacc aaagcaagaa ccgatggtag ggatatatat attatcaata
    17521 ataagatagc atccattaaa ccctcctgat atgtaggata tcttatgcga tacagcaaat
    17581 tgattgacaa tttttataat atcaatgggc gtatcaattg ctttaacgat aaaatctata
    17641 ctcccatatt ccgcaacaat tttttctaat tcttctaatg aagaaacttt aatagaaata
    17701 ggtactacct gaacatctga attatacttg tgtatttttt cagaaagaac attaatcttc
    17761 tccttaccaa catccgactc tgtataaaga atttgcctat ttaaatttga tggttctatt
    17821 atatcgtaat cagcgacaat aagtttcctc actccataca tacttagact taaagatata
    17881 taacatccta aggctcctgc tcctaatact aatactgttt tattctgtat tttattatac
    17941 tcttcattat aaaataacga atagtaacct ttagttctag aatatctact atcaatatct
    18001 atctcatccg aaattaaaat ttgttcattt aatagttcaa atgttagttt actgcctaat
    18061 acttcttcta tctctaatag ttccttgatc gttgataaat tcttgcgaaa tttgaggttc
    18121 tatagctatt tcccgcatac tccgaccacg taaatacatt ataccttctt ttttataagc
    18181 aaaaacataa ctatttacgt agaacatatt tcgtccttcc tatcatatat aatatagaaa
    18241 gcagtataga aacaaccacc cctcctatac tacgaacaat aatattgggt gtcaaaaact
    18301 gtaatagttg actcaaaggg aaataaataa taacaaatgc tattaaaagt tgaactatat
    18361 attgaaaatt caagttatta ttgttagaat tcaagtatct taaaataata ccactatcat
    18421 actgaaaaaa aggaattgaa ttaataaaaa tcatacctaa gttaatgata aaaaataaga
    18481 gtccaagcaa tttatacgat gtgaacaata aaacaagtaa acctgtaagt gataaaatcg
    18541 aatttgaagc aattcctgct aacataattt tcaaaaattg ttttttattt tttaggaatt
    18601 gcaccccact taaatctaca aaaaaagcca aattaaacaa aagtagcatt attccacaat
    18661 ttgggatctc aatttgataa ttattagcaa ttattgcatg actaaattca tgtatcgttg
    18721 cagatataat aacaacaagc aaccaaaata aaagaatgtt tagcgttatt ggaaagtttt
    18781 ggaaattagt caaaatatcc gccctataaa tatacataat aaaacattgc aaaataagag
    18841 ccaatgggaa aataccaaat aggatttttt caaaattctt attaaatctt ttatagttta
    18901 atttttcaga taatgttata ttaaagtccc aagatatttt aaaaatattt atcttttttc
    18961 gtgatttcat agaatctata agtcccattt tactaagaac aatataaaat cttaaataat
    19021 atttcttccc tactaacact aataagtccg atatggtaaa ttcttgacct attagttgct
    19081 ctaaccattt ttttcctgtt tcccaactaa tacatgtttc ttactggatg gtatatatag
    19141 atgatactgt ccctcataag gagtaggtaa tatcttaatc ttatcaacaa ttctcataac
    19201 aaacctaacc tttaataaat aaaagagggg ctaagtaaaa catactctag tccctcagtc
    19261 cgcaatcaat aaaataatga ctaattctat taatctcttg ctgcaagact aatacggaaa
    19321 attcaaatga ctgtctaaaa tgaaattgaa aaagcttgat gttagtaaat gaacaaactt
    19381 caacaaccag caagagcaag gattgctaaa ccaaatccga tacctgttgc aagtccagct
    19441 gaaaaatcac taactggtac tgaaatttct tcaatttcct caaataaaaa gttatcttgc
    19501 atgattatca ctccctatct ttttaacaac aggctactcc aattaagaga actaccccag
    19561 ttccaagtaa aacttccccc aaaaattcac catctgtagg ggctacgatt tcttcaattt
    19621 cttcaaataa gaatacttca tctgacatat gtgttacctt cttcatcaaa aattattttg
    19681 taatcgatta cattgcagat gtaacataaa gaaaaacaaa tgtcaaatat taaacgtaaa
    19741 aacatggtca ctaaagaact ataagagaaa aggtaaacct agcgacgcga tgaacgctga
    19801 tttgtttgat ttcgattgct ctcttcctct tgttttttct gttcttcttc ttgttttttc
    19861 tcagcttcct tggcctcttg tttggctttt tcctcagcct ccataattaa tttatccgcc
    19921 acagtgtaac tgtaaattcc agcttccatg tcgaccacac tcggttctga caattgtggc
    19981 ttaatcttac tgtaatatgg cagtttctta ctcatttcag atagaggaac caagacttcg
    20041 tccgaatcat tcatggtcaa tcgaattaaa tcggatgtca ccttgcttgg ggctaattcc
    20101 accttttgga tagccgcctt gagttctggg ctaatttgag caagttctga gacaaaaacc
    20161 ttgatttgtt cactatcatt aaagagaact gataaataag tttctggtaa actgttcaga
    20221 ctcacagaac tagtctcaag ctgaccactg gaaagaatag gataatgatt ttcaccagaa
    20281 atatagtagg ccacaatatc atattccttg accttaatag tgaacttagt tggaaattga
    20341 tagacaagtt gagctgattc aacccaatag ttagacttaa tctgcttttc atattttgcc
    20401 ttgtctagca gaaggttaat cgtataatcc gaatcctgaa tgcctgaagc ctgtcgaata
    20461 tcatcagctg tagtttgcac cgttccctca acacgaatat ctttcatggt cgcataagga
    20521 ctgagcaagt aggcagagac aatcaataaa agcagacttg gaaataaaat cgtgaaggct
    20581 cgcaagatat ggataccagg aatctttgct ttggctggtt tttcctttgt agccttttta
    20641 gcaagctttt tatcctgttc ctccttctct ttagactctg attcttcttt ctcttctttc
    20701 tctttgtcag cctctgagga tgctactttt tcttcagact cttccttagc tgattctgaa
    20761 tcttcctggt ctgtttcact ctcctggtcc tgtttgtcct ctgacttctc agattcttct
    20821 cccatccgag cttgtctttc cttttccttc tcctcagcta gagccgcttc ttcttcagcc
    20881 ttctttttta gatattcttg gtttcgtttc tgccattctg ataactcttt caattcttcg
    20941 aggatttctt tgtcctcatt tttcttatct tttgacattt actttcctta tgataaatct
    21001 tttttcaaca attgataaaa atctgctaga gatttcaatt ccttagaagc tttcatctta
    21061 gcttggtaat cttccttgtg acttagtaag tgagaaagct tctcttccaa actatccaag
    21121 gtcaaatcgc tttcttgaag gtcttctgca tagcctttct taacaaagta agctgcattt
    21181 tcaatctggt caccacgact agcttcacga ccaagtggca caatgacatg caattttgct
    21241 atcgccaaga gctcaaaaat cgtattggca ccaccacgtg tcacaacaat atcagccaat
    21301 tccatcaagg gttgatagag atcggtcaca tagtcaacac gaaaaagatt ttggctcaac
    21361 tcattcaggc tagaatctcc agttagattg ataatattgt agcgctctgt tagttctttc
    21421 ttatggtctg tcaccaattg gttaaagaca cgagcacctg cagaaccgcc aacaaacaat
    21481 acagtcggca atttatgatt aaagtggctt tgaatatcca ccaattcatc tggttctgga
    21541 tttttttgat ccgaaacctt ggtcaccgct cccacatgct cgaccttagc caaactcgaa
    21601 gcttgttcaa aggttgaata catcttagtc gcaaatttat aggcgatttt attggccaag
    21661 cccatagaca ggtcagattc gtgaataaag acaggcactc ctgacacacg cgcagcgata
    21721 acaggcggta ctgagacaaa gcctcccttt gaaaaaaggg tctgtggacg aagtcgcaac
    21781 atgataaaga gcgattggac gattccccag ccaactttga agacgtccag catattttgc
    21841 caagagaaat agcgacgcaa tttcccagtc gcaatagaat ggaaggtgac atccaaacct
    21901 gacttaagga tttcttggtg ttcgatacca cgcttgtccc cgatatagtg gacttcccaa
    21961 ccatcttcga tgaacttggg cattaacaaa agattgaggg taacgtgtcc aaccgtcccc
    22021 ccacctgtaa agacaatttt tttcatattt tattctttta actccgctac tgtgtcgata
    22081 aagaggtcgc cacgtacttc aaagttagca tacatatccc agctggcatt ggcaggacta
    22141 agaagaacca catctccttg agtcgcaagt tcataggcct tacgggtcgc atctgcaata
    22201 tctgtcgcct ccacataagc gacaccagcc ttgtctgctg cccgtttgac acgttctgca
    22261 gattgaccca ggatgaccat cttcttgagt ccagtaatgt ctggcaccaa ttcgtcaaac
    22321 tcattgccac ggtccaaacc acctgcaatc aagacgacct tgctgttgtc aaatcctgat
    22381 aaggcttttt gagtagccaa gatattagtt gatttactgt cgttatagaa tttaacaccc
    22441 ttgatgtcat ccacaaactg gagacggtgt ttgacaccac cgaaggctga aagagtttcc
    22501 ttgatggttt gattgtccac atcacgaagc ttggctacag caatagtcgc aagggcattt
    22561 tccacattgt ggctacctgg aacaccgatt tcattcgctg ccatgactac ttcaccacgg
    22621 aagtagagtt gaccatcttc cagataagct ccatcaacct tttcaagtgt tgaaaatggt
    22681 acaacagtgg cttctgtctt ggaagccaag tcttttgcca agtcttgatt aaagttcaag
    22741 acaaggaaat cagctgctgt catcttgttc tggatattcc acttggctgc tacatattcc
    22801 tcaaataatc catgataatc gatatgagtt ggcataaggt tagtaataac cgcaatctca
    22861 ggatggaatt cttgaacacc catgagttgg aaagaagaaa gttccataac aagcgtgttc
    22921 ttgtctgtcg ctatttgagc aacctgacta gctggatagc cgatattccc tgataaaaga
    22981 ccatgttgcc cagcagcagt caaaacttcc ccaatcatag tcgttgtggt tgtcttaccg
    23041 ttcgatcctg tgataccaat aatcggtgct tctgaaatca aataagccaa ttccacctca
    23101 gtcaagactg gaattccctt ggccaaagcc ttttcaatca tgggattgtt gtaggggata
    23161 cctggatttt tcaccataag agcaaactct tcatccaaga gttccaaagg atggccacct
    23221 gtaatgacct tgatcccttc ttccagcaaa ctttgggcag ctggattgtc ctcgaaaggc
    23281 ttcccatcat ttactgtcac aatggcacct agcttgtcca acaaacgagc tgcagattca
    23341 ccagacttgg ccaaacctaa aacaaggact ttcttatttt taaattgatc tattactttc
    23401 atgtctcgaa ctccatttct actcctacta ttttaccatt tttatggaaa taaaaaagcc
    23461 acaaagtgtg tttgtgactc tttcttctag ctgaatcttg ccatatcatc tatgtgataa
    23521 atcggtaact cgaataactt ggtccacttg ttcccaaata agaggattgt gggtcgcaat
    23581 aataatagtt cgattcggat tttttaaaga ttctaggatg gaaagtaatt cctcagagtt
    23641 tttggggtct aaggaagcgg ttggttcatc tgcgaggatc aaaggtggat cctttaaaat
    23701 tatcttcgct aatgcaacac gttgtgcttc tcctcctgat aactcaaata taggttgctt
    23761 caaatccaaa taagagaggt ttacacggtt tagagcttgt ttcatcaaag agattttctc
    23821 tttttccttc aactttttac caactaaacc cagattgaga ttctctttga cggtttggct
    23881 ttcaattaag ccaaaatctt gaaataagta tcctaagtaa tctctaaaga aaacagaagg
    23941 cttgatgtcc ttaagagaag tgccatcata gatgatttgc cctttgtcat atggctctaa
    24001 tcgtccaatc atattcaaga gtgttgtctt accacagcca cttgtaccga ttaaggcata
    24061 aattttccca ccttcaaaat gaagattcgt atctgaaaat agctgacggc ttccaaattt
    24121 tttagatata ttctttagtt caatcatcct attttccttt cataattgtc atagaaacac
    24181 gagattcttt ctgcgcttga cggtaaagcg tcagaactgc actagctaga aagactaata
    24241 aagtgagcaa gccaatcacc aagtctcgac tgcttaaaat aaaaagacta gcaccaaata
    24301 caaaactggc aaattgacta accatatact gagcatgtgt ttcaaaaaat cgtaaacctg
    24361 aaattcgttt aatcaagata tctcggcgga attgctcgaa atatagaaga ttgacagaat
    24421 aaaatagtaa caaggaacta gctatcccca caatagctcc taagattaaa gttgctgttt
    24481 cagtttgaac ttcattataa cgagttagat aaacacttct tccttcttta agataggata
    24541 cttgctcata aattccagct ttcttcaaaa gttctagccc actctcatat cctttgataa
    24601 agagttgttt tccagcattg atagaccaac tagataggga tataaaacta tcacctgtag
    24661 aagtcggcgt gaataccact aaaatcggat cagtcaaata ctgagtggat acgggattct
    24721 caccgttatt ataaacaaac cgcttttctc ccattgaaag ataactaacg tgcgctttca
    24781 tctcataatc caaaggagca cttgcctcct caccagattt tccataataa ctcaatcttt
    24841 cttcaaaaac tttcttaagt tctgcttctc gagagcgcaa atgttctggg agcaagagga
    24901 taaactcacc tttttggaga tgggctaact tctgtttggt ctcagcatct accacgacct
    24961 tttccttgtc caaataactg ggactaacat agagcgtatt agcatctgga ctataggtat
    25021 ccagtgtctc tccctgttca ttttttcctt gtggattggc aaaatggagc agattatcct
    25081 ttacataaag agcttgttct tcttcgattg cttccttggc aaaggcatac cacttgctct
    25141 gattttctgt atcttttcct ctatcaccta agccaaaaga aatttgataa tagtctgctc
    25201 tatcctgcca tgcttgtttt gaaatttcaa gttctttcaa tcgttggtaa gacgtcaaac
    25261 ctgtcttaac agcgtatcct actgtaaaga cagcaaccaa ctgacacaat agggttaaaa
    25321 tcatcaggcg tttaaggggt aatctcccct taataacggg aactaatgct ttgtaattca
    25381 aactcattag ataaagaagc attagtaaaa ttgaaatcgc caataaaaac aacagataga
    25441 aactaatccc aaaaccatag gtggctaaca agataggata aaacaaacct tgactaaaaa
    25501 gaacgactcc cccacctagg aaggaaagga gggctgatag aaggagccat ttgatatcag
    25561 tagataaaga atgccccatg atggataaga gagtctgacc agaaaagagt tttatacctg
    25621 ctgctctcat ttccttaatc cgagtgataa tcactaaagc aaagaaagat aagccaaata
    25681 ttgctaaact aattaaaata aggggattta gtaatattcg aaaagcaaga aaatagggcg
    25741 gtatctttcg gtcagcactt gctttataac ccaaatctcc taatttatcg gcaagctttt
    25801 ctttcgtcaa ggagcctgac aaaaggagat aactatttag cggatcacta cgttcacgac
    25861 tttcttggct agcttcttgg aattcttttg gtaaagttcc ctgaccataa gttgcataag
    25921 taaagtgagt cgtcccatcc ttactcggct ctacaattct tctagctatt aaactctgtt
    25981 ctgagtttgc aaaattctcc aattcctgtt caaatacctc acgcgtcggt tcctgagtat
    26041 cttttttgac acgaagtaaa gaaacggaat catagcttgc atataaatat tgtggcgcac
    26101 gtaagacaat aatccaagca aggaagaagc tgagaaaaaa agttgataat aatatgaata
    26161 gtttcttcat agtagactcc ttgtaaacaa aattccccct gtaatttctt acaaggggaa
    26221 cgatttaaat caatgaacga ttagtcataa tcacagtaaa atgctacttg ttctccccat
    26281 ttagtccaaa tccatgcata ggaggttttt ccagcaggag cttctccttt atcagaatga
    26341 ccatcccatc tgctcacgat ggatgaataa tgatattttt taccatgata gtaatttgaa
    26401 aaagcctaac cacctcctga accttctcca tatgtccata ctcctccatc tggatattgt
    26461 acagcagctg atgcagctcc caataatgta aaatttgaaa taagagctag agcaagtaat
    26521 ctatgttttt tcgttttcat tttatttttt ctttcaaaaa aagcacacct tgagcaacaa
    26581 tgcaacaaaa taaatcctcc tctctctttt attgaaaccg ctttcttatg tgataagaat
    26641 aactttttta ttatttgttg tcaaggaaaa aatcgaattt tttagatatt ttactatatt
    26701 acctctgtga ataatattat atagtagttt tatttcaaaa taatatgcaa ccagtactaa
    26761 ccaaatataa aatagatgcc attaacgaat tttattcaag tttttcccat tcatactata
    26821 caagtaaaag agatggtgtt aactaaaaag caattcaaac tattgtaaaa ttcctagcaa
    26881 aaagagagcc gaaactctct tttttatctt cttttacttt ttttgactgg catgagtgtg
    26941 atgtctctaa cactaaagta agctaggatc aacatggcta ttgctaggaa tatttctgtt
    27001 ggtaattgaa aaattttcag aaaagataga accaataaaa tcaagagtgc cactaaaata
    27061 cataccatag cgacgatatt gacagtccct ttaatgcttt ctggtgtcgc aaatacatag
    27121 agtaggagca gtaaaattcc taggactaaa tagaccatct ttctctcttt ctagctctta
    27181 ttcagctgat tttttcttct tgttagcttt ctcacgctct gctttgttaa ggatttgttt
    27241 acgcaaacgg atagactcag gcgttacttc catgtactca tcgtcgttca agaactcaag
    27301 agactcttca agtgtcaaga tacgaggcgt cttgataaca gctgtttggt ccttagtagc
    27361 tgaacgaacg ttggtcattt gttttgcctt cgtgatgtta actgtcaagt cattttcacg
    27421 agagttttca ccgatgatca ttccttcata aacctcagta cctgggttga caaagatcgt
    27481 accacgttct tcgatagaca tgattgagta agttgtagcc ttaccagcat cgatagaaac
    27541 aagggcacca cggtgacgtc caccaatttc ccctggaatc aatggcaagt attggtcgaa
    27601 ggtatggttc atgataccgt aaccacgagt cattgataag aactcagttg agtatccaat
    27661 caaaccacgc gctggaacaa ggaagaccaa acgagtttga ccattaccag ttgaaatcat
    27721 atccaacatt tcacctttac gttcagaaag gctttggata acagaccctt ggtattcttc
    27781 tggagtgtcg atttgtacac gttcaaatgg ttcacattta acaccgtcga tttcttttac
    27841 gataacttct ggacgagata cttgaagttc atagccctca cgacgcattg tttcgataag
    27901 gattgacaag tgcaattctc cacgtcctga aacagtccat ttatctggtg aatcagttgg
    27961 gtcaacacga agggaaacgt ctgtttgcaa ttctgcctgc aagcgttctt ccaccttacg
    28021 agaagttacc catttacctt ctttaccagc aaatggtgag ttgttgacca agaaagtcat
    28081 ttgaagagtt ggctcatcga tgtgtaggat tggaagagct tctactgcat ctgtcggagt
    28141 gatggtttca ccgacaaaga tgtcttccat acctgaaacg gcaatcaagt cacccgcttt
    28201 ggcttcttgg atttcacgac gttccaaacc aaagaaaccg aagagttttg taacacggaa
    28261 gtttttagtt gtaccgtcaa gtttagaaag ggtaacttgg tccccaacct taactgtacc
    28321 acggaagaca cgaccgatac cgatacgtcc aacgaagtca ttgtagtcca aaagtgacac
    28381 ttggaactgc aaaggctcat ctgagttatc tactggagct gggatatggt cgataatcgt
    28441 gtcaaagatt ggtgccatag tcgcttcttg gtcagctgga tcatctgaca atgaagaagt
    28501 tccgttgatc gctgaagcat aaaccactgg gaaatcaagc tggtcgtcat ctgcaccaag
    28561 ctcgatgaaa agttccaaga cttcatccac tacttctgct ggacgagctg atggcttatc
    28621 gattttgtta acaaccacga ttgggacaag gtcttgttcc aaggcttttt tcaatacgaa
    28681 acgagtttgt ggcatggttc cttcataggc atctacgacc aagacaacac cgtcaaccat
    28741 tttcatgata cgctcaactt ctccaccaaa gtccgcgtgt cctggtgtgt ccataatgtt
    28801 gatacgagtt ccgttgtaag caacggcagt atttttagca aggatggtaa tcccacgctc
    28861 tttttcgata tcgtttgagt ccatagcacg ctctgccaat tcagtacgtg catcaagcgt
    28921 ttctgattgt ttcaataatt cgtcaaccag ggttgtttta ccgtggtcaa cgtgggcgat
    28981 aatcgcaatg ttacggatat cttctcttaa ttttgtcatg atttcctcta taatattcaa
    29041 aatttatttt ctaactgaac gattatacca taatttcaaa taaataacat aactcaagca
    29101 agtgtaaatg ttttcactcc gcttttcttt tcacgtcaag ccttttcaaa gcaagcgact
    29161 tatgataaga taggcacagt atgcgtttag ataatttatt agcccaagaa aaagttagcc
    29221 gaaaggccat gaagcaagca ctcctcagag gggaaattct agtcgatggt tgcccagccc
    29281 gctccctagc tcaaaatatc gatacaggac tacaagaact cctttttcag gatcgaatca
    29341 ttcaaggcta tgaacacacc tatcttatgc ttcataaacc tgctggtgtc gttacagcca
    29401 acaaagacaa ggaacttccg accgtcatgg acttgcttcc atctgacatc cagtctgaca
    29461 agctctatgc cgtcggccga ctggaccgag atacaacagg actccttctc ttgaccgata
    29521 acggtccctt gggcttccaa ctcctccatc cccaatatca tgtcgataag acttatcaag
    29581 ttgaggttaa tggacttcta acacctgacc atatccaagc ctttcaaaag ggaattgtct
    29641 ttttagatgg tactgtctgt aaacccgcaa aactagagat tctatctgca agtccctccc
    29701 tcagtcaagc ctctatcacc atttcagaag gaaaatttca tcaaatcaag aaaatgttcc
    29761 tctcggttgg tgttaaggtg actagcctca aaagaatcca atttggggac ttcacattga
    29821 acccagattt agcagaaggt aactaccgcc ctttgaacca aaaagagtta caaatcatta
    29881 aaaactattt agagatgagt cgataaaaca aaaaaagctt taaaactaaa gcttttttct
    29941 tttatttacc gaaaaattaa ggcgattgct acaatccagt taactacaga aatcacaatt
    30001 cctaagatat taagaatctt ttctatttta tactctaatt gtgactcttt ttggtatgaa
    30061 atagccaaga ccaatcctat gatacccaaa atcaggccta caattggaaa taacaaacca
    30121 agaataatcg acaagatacc cacaaaaagt ggatttttct tcttttcttt catgttctaa
    30181 gaactcttta aattttatac aaattaatta tactataaaa caatagcttc atcctatcat
    30241 tcgactaatt tggaaataag gttagctagt cttcactttc cctttccaag aatccaagcc
    30301 ataagaaagg atataaatct cagaaaaacc ttgttttttc aagtaaagag ctgcatttgt
    30361 aactcgttgc gcacgttggt tctcgtagag aaggacaggt ttatctttac gaagggctgc
    30421 aagactagtt ttcaactgac ttgaaggaat attgcgtgca cgaaggatat gttttctgtg
    30481 gaattctgct gggtcgcgca aatcaatcaa ttgacccgta cgaatcaagg cttcaaactc
    30541 ctcattgtcc acaattttag ccgcacggcg aatacgaaga tagttaaagc ccatccacgc
    30601 caacattgct agtataagtg cccacaaaat ccaagtaacc attagttctt ttctccattt
    30661 ttctcaatat aatccaattc taccttgtgc tctctgcgaa gaactgcttc tgcctctaga
    30721 tagtctaatt tatccatcaa ccctgcatcg taaatccgag atagttccaa cttcatcagt
    30781 tcaatatcat ataagcgttt tcccatgtaa acaataatac caaatcgttt gaggaattgc
    30841 tgcacatcat agaatgtttt cataagactc attctagcaa aattttgtgt ttttttcaag
    30901 aagagactca cacaatgctc cttattttcc tatcttcttt ggcgattcta aggcaagtgt
    30961 ggtacaataa aaacatgaga attcaacaat tacattatat tatcaaaatc gtcgaaactg
    31021 gctctatgaa tgaggcagcc aagcaactct ttatcactca gcccagtctc tccaatgcag
    31081 tgcgagattt ggaaaatgaa atgggcattg aaatctttat ccgcaatccc aagggtatta
    31141 ccttgacccg tgatgggatg gagtttctct cttatgcccg tcaggttgtc gagcaaactc
    31201 agcttctgga ggaacgctat aaaaatcctg tcgcccaccg cgaactcttt agcgtttcgt
    31261 ctcaacacta tgcctttgtg gtcaatgcct ttgtctcttt gctcaagaaa agcgatatgg
    31321 agaaatacga actcttcctt cgtgaaactc ggacttggga gattatcgac gacgtcaaga
    31381 acttccgcag tgaggtcggg gtcctcttct taaacagtta caaccgtgat gttttaacca
    31441 agatgctgga tgacaatcac ctgctatccc accatctctt cacagcgcaa ccgcatatct
    31501 ttgtcagcaa gaccaaccct ctggcaaaga aagacaaggt gaaactgtct gatttggaga
    31561 atttccctta cctcagctat gaccaaggga cgcacaactc cttctacttt tcagaagaga
    31621 ttctttctca agaacaccac aagaaatcca ttgtggtcag tgaccgtgcc accctcttta
    31681 atctcttgat tggtttggat ggttatacca ttgcgacagg gattttgaac agcaacctaa
    31741 acggagacaa tatcgtttct atcccactgg atattgatga cccgattgag ctggtctata
    31801 tccagcatga gaaaaccagc ctatctaaga tgggcgaacg ctttatcgac tatctactag
    31861 aagaagttca gtttgatagt tgagaaatga taagaaccaa tatgtaggct agcaacaacc
    31921 tgcacattgg ttctttttac ttataattaa aagtttcccc tgccaactta tcagctagct
    31981 tgggaaagag agtataaaac ttatgggcta ggttcaacaa aatcgggaga ttgagttctc
    32041 gtttattttt tcctataatc ttgacaatct ttttagccac tgcatctgcc tctaagagga
    32101 agcggtcaac cgatttaaga taagttccat ctgggtcagc ttggtcaaaa aatcctgttc
    32161 ggattggacc tggattgact gttgtcacat agactccata gggcataagt tcgagtcgca
    32221 gagcatttga aaaaccaata gccgcaaact tggtcgctga gtaaagacta gacttgccag
    32281 tagctattag acctgccatg ctgacgatgt tgatgatatg ccctttgctg ctttccttca
    32341 tacgagccgc aaggtgacga gacagattca tcagggcaaa ggtattgacc tcaaacatct
    32401 ggtgaatgtc tttatcagca atctggtcaa atccctcaaa aatcccgtaa ccagcgttgt
    32461 taatcaagac atcaatcttg ccatagcgga gataaagatc agttaccaga gcttctaggg
    32521 ctgaatcgtc ggtaatatca atttcaatca attctgcatg ggaataattt ccgtagagtt
    32581 gggctaattt ttccttattt ctaccaagca agatgagttg gtcattgggc aggagtttga
    32641 ccatttcttg agctagacca ccgctagctc cggtaatgag aatagtaggc atacttatcc
    32701 tttctgtgac tgctagattt ccacttcttc caagtctttg accacatgga cattttcaaa
    32761 aattgtggca gcgtctttct tgagtttgct aatatctttt gagaggaaac gggcactgat
    32821 atggttgagt aggaggcgtt tggcacctgc ttctaccgct acttgtgcag cttgcatatt
    32881 agttgagtga ccatggttac gagcaatttt ttcatcaccc ttgccataag tggactcatg
    32941 aactaggaca tctgcattga cagccagacg cacactagca ttggtttttc tagtgtctcc
    33001 taaaatagtg ataatcttac ctggacgtgg cgctgagata tagtcagccg ccttgatttc
    33061 agttccgtct tccaaaacaa gatcctggcc gtttttgatt ttaccaaaaa gcgggccgaa
    33121 cggaacacca gcagccttga gtttttcagc atccagcgtc ccttctagat ccttttgcat
    33181 gacacgatag ccaacacaga aaatagtatg gtccagctcc tctgcataca cagtgaattt
    33241 atcggtctca aggatttttc ctagagaatc ttggtcaaac tcatggaaat gaatgcggta
    33301 gggcagacga gaacctgaca cacgaaggct ggttaagaca aatgacttga ttccttgagg
    33361 tccgtagatt tccaaatctg tctgctcttc attggcctga aaggcacggc tagaaaggaa
    33421 acctggcaaa ccaaaaatgt ggtctccatg cagatgggta ataaagattt tgctgatctt
    33481 acgtggtcga actgtggttt ccagaatgcg attttgcgta ccttctccac agtcaaagag
    33541 ccaaacttcg ttaatctcat ccaaaagttt cagggcgaga cttgaaacgt tgcgagcttt
    33601 agagggctga ccagcccccg ttcctaaaaa ttgaatatcc attcgatact ttctaattaa
    33661 tcaatatata acatggctgt gcggttttcc gatcggaaat agcgtttgcc agaaaaagca
    33721 gcagcttctt gcaataaatc ctcttggctg tagcctttga gacgttttcg accatcagcc
    33781 aatctttcca aatcagtcaa agctgtgaga ctttctaggc tgacaacttc ctcgtcctcg
    33841 acaggcttca tgtaaatctt accagactct tcaaagacta attgatgggg gaaaatttgc
    33901 gcaatttcaa agagcaagtc atccgagatt ttctcctcat tttcagagaa aatccgacca
    33961 aggccgtcac tatcataaca aaaaccaaag gatttaccag acagattaag ccgaataaaa
    34021 ggcttatttt ctagggtgaa acttggctca gtattgtaaa gattcagttc ctgactgagt
    34081 tctgcaaaat aatccgtcgc agcctgagga ctctttttct gatagagttc tgcaaagtag
    34141 gcattaacaa cacttggcgg aggtgtaata agtgttaact gctcctgctc tgttttacca
    34201 gctagaagct gaaccagata gaccttgtcc agacttgtat aacctccata ctttagagcc
    34261 aaagctttaa tatcagtcat aaaattcttc taacctccat ttattttttt cggaaatgta
    34321 gcctgtaatc acttcgctgt cttcctgata atcacgttct tccagaattg caacactctc
    34381 taaatcatga atcttgtagg actttgaaaa aggcactcgc agggtaaatg cttcaaaaat
    34441 ttccttaatc ttatctagca ataatgcttg caagttttca cgactgtcct cagacttggc
    34501 agaaatgagg gtatatggcg tttgggtagg cgtgaaatcc tccaccaaat ccgctttatt
    34561 ataaagcgtc aagtgaggaa tatcttccat gtccaggtct ttcatgatgg agagaaccgt
    34621 tttttcatgc tcctcgtggt aaggattgct agcatcgata acatgaacca gaaggtccac
    34681 atgcttgctt tcttccaagg ttgacttgaa actggacacc aactctgtcg gcaaatcttg
    34741 gataaagcca acggtatctg tcaaagttac ttggagattg cctcccagat gaatactctt
    34801 ggttgtcgca tccagagtcg caaagagctc atctgcttca tactgggtct tactggtcaa
    34861 gatgttcatg atagttgatt tcccagcatt ggtataacca atcaaaccaa tcttaaaagt
    34921 gctagactcc aaacgttttt ctctgacagt cgcacgattt ttctcaacca ccttgagctg
    34981 gcgctcgata tccgtgattt gattgcgaac gctacgacgg ttcagctcca gctggctttc
    35041 accaggacca cgggaaccaa ttccccctgc ctgacggctg agcataatcc cctgaccaac
    35101 caagcgaggc aaaaggtatt tgagttgggc taggtggact tggaacttcc cttcatggct
    35161 tcgagcccgc atggcaaaga tatccaaaat caactgcata cggtcaatga ccttaacacc
    35221 gagaacttcc tctagattga cattctgcct tggggtcaga cggttgttga cgatgacagt
    35281 agtgatttct tctgcatcca ccataagcgc aatctcttcc aacttaccag agccgacgaa
    35341 ggtcttggaa tcatattttt cacgtttttg tctgtagcta tctacaacga ctgcccctgc
    35401 cgttttcgct aaactagcca attcttccat ggagaggtca aaactgtcca taccctgcaa
    35461 ttccacacca atcagcagga ctcgctcctc ttttttctcc gtttcaatca tctaaaaact
    35521 cctctatctg gcttaaaatg cggtcttgta caccagattc tccaatctga taaaaggtga
    35581 cctgcatgcg attacggaac caggtcagct gacgcttggc aaaacgacgg gtcgcctgtt
    35641 taagactctc actagcttcc tcaaaggtct gctctccacg gaaataagga aagagttcct
    35701 tatagccaat tcctttagca gcctgtacat taggggaatg gtcaaacagc cacttggcct
    35761 catccaaaag cccagcctca aacatcaaat ccactcggtg gttgatacgc tcataaagtt
    35821 gactacgttc atcatccaag cagataatca gcggttcata caaggtctct tgattttcca
    35881 aatcctgacc aaaatgggca atttctaagg cacgcatagc acgacgacga ttaaactggg
    35941 gaatctcaag gcctgcttgc tccacaaaat gggctaattc ctcatctgaa tacggctcca
    36001 aactagctcg ataagctaaa atctcctcat gaggagtctc cccacctagg tggtaacctt
    36061 ctagcaagct ctggatataa agtccagtcc caccggcgat aatggctagc ttgccacggc
    36121 tgtgaatatc ctcaatagtc atcttagctt ctgaaacaaa atcaaaagcc gagtaagact
    36181 cggttatctc tctaacatcg attaaatgat gaagaacagc tgcctgctct tctggactag
    36241 ccttagctgt cccaatatca agtcctcgat agacttgttg gctatctcca ctaaccactt
    36301 cgccattaaa acgctttgca acttcaatag ctagagccgt ctttccaaca gcagtcggtc
    36361 caacaatcac aattattttt gttttcatct tttttccttg aaaaattccc attttttcgt
    36421 tactattatt ataacacaaa aaggtcagtc agaaaaatgt gacctcttga ggaggctggc
    36481 tgattgagaa tataaaggag gaagactcat ggctaaagga ttcgctaaag gtcttgtaac
    36541 aggtgtcgca ggaactgtcg ctgccgttgc aggtgcagta tacgcattta aaaagaaagt
    36601 aatcgaacca gaagagcaaa aagcagcttt catcgaagaa aaccgtaaaa aagcagctcg
    36661 tcgccgagta tcacgttaag aaacaaaaga agttgggatt attctcaact tcttttttct
    36721 attcttttaa atagctaggt caaacttcaa ctgtggctta acagggtcat aatccaccaa
    36781 ctcaaaatct tctgctttga tatcaaagaa attagtccca tcaggaacat ttaaaaccaa
    36841 gcgtggttgg cagtttgacg gctcccgacg gagcaattcc tgagcttgtt caaattgatt
    36901 atcatagata tggaggttgt tgatgaagta gaagaacttc ccaaccttcc agccaaaatg
    36961 tttggcaatc atcatctgca aagccacata ctgcatagcg ttgatgtggt gggccaccag
    37021 catatcattc gagcgctggg tcaaggtcgc atccagatag atttctccat ctatacggcg
    37081 gacatcaaac atggtctgaa aggcgcacgg gagcagccca tctgtttctt cgaaagcttg
    37141 gtaatcccag agcgaaataa tattgcggcg gttccaagga ttggtttcca actgtttgag
    37201 aagcttattg ataatgtcgt gtttcttaac aacggcacca tagcgctcac caatggttcc
    37261 cgtgtctcca acttcccagt cattccagta gtgaacattg tacttgtcat taagcacttc
    37321 taagctattt gactggtctt ggtaaatcca gagaacttct ttgatggcgg atttgattgc
    37381 aatgggacgc aaggttgtga taggaaattc tcctttagat aagtcgtact cggaaaaggc
    37441 accagttaca tacttggaat tagcaacagt cccatccttg tacttaggac gagcctgctc
    37501 tgagaaaaca ccttccttta gaatgcgttc aatattctct ttaaaaatcg tatctgcttt
    37561 tgtcatttcg tttcacctca ttcattgtcc taactagtat agcataaaaa ataaaagagg
    37621 aacattacta actctaggtt agcattttcc tctctcatta tcttattgca atacaagtga
    37681 tgctgctccg ataactccag cgtcatttcc tagagttgca agagctaatt tagtagatgt
    37741 gcgtacttgt gggaaactat tttcatcgta aactttttga acaccttgta gaaggaattc
    37801 tcccgcagct gacacaccac caccgatgac gattgttgat gggtttagga ttgaaccaat
    37861 gttagcacaa gcgattccca agtaacgtga gaagttacgg taaacaatca aagcaaggtc
    37921 gtctccttct tttgcgagat caaagacagt cttagcagtt acttcttctc cgttatcaat
    37981 caagcgtttc aaggctgcat cgccttcgta ttcatcggca tagcgacgag tcaagttgac
    38041 aatccctgtt gctgaagcaa ctgtctcaag gcagcctttt ttaccacaag tacatgagat
    38101 tggttggtca aagtcaacag tgatatgacc aagttcacct gctgcaccag caacaccatg
    38161 aagcaatttg ccttctgcga caataccacc accaacacca gtaccgagtg tcataaagac
    38221 aacgtctggt tggttatctc cagcacccat ccagcgctca ccaagagctg ctacgttggc
    38281 atcattatcg atgaaaaatg gaatgcccaa agctttttca atcttttgtt tgattggttg
    38341 aagggttttc cagttcaagt tgtaggcacc gataacagtc cctttgtcac ggtcaaccac
    38401 acctggtgat cccattccaa tgccttggaa gtccgctgct gccaatccaa gcaagtccaa
    38461 acgatgttga atagactcaa tcatatcatc aacgatatga cttccctcat ccaaaatgtt
    38521 ggtcttgatt gaccattttc cttggatttc tcctactgtt gttaagattg caaatttgat
    38581 agaagttcca ccaaggtcaa tcccaataat cttttgactc atcatattct cctttttcat
    38641 tgtgtagtaa ttgaaaatgc ttacagtact agtatatcaa aatccattca cttatgcaaa
    38701 ggtttgcgta aatgaattat aaggaatttt ttcgcctacc agtatctgtt aatcatctaa
    38761 atgatcaatg gcatattgag ctgcatcatt tgaaaattta tcaaaatcag aagttaattg
    38821 tctatacata cgtttttttg acatgtggaa taacgaatta taactttttg cctttcctaa
    38881 agcagcagaa tattcactat tgctatcatt actagaagaa actgtacttg cttgaccttc
    38941 cttccaaact ccgtcagcgc caacataata acgtccacca tcaacccatt cattgacagc
    39001 cattttacca tccgatttta gatagtaatt tccttgccat gtactgtaag cataagaacc
    39061 atctgatgtc aaataatacc aagcttgata ggtggcatca taaacccatt cacctttagc
    39121 cattttacca tctgatttca aatagtagtt tccttgccat gcattgcgag catatgaacc
    39181 atctgatttc aagtaatacc atgcttggta agaagaatca taaacccact caccttgtgc
    39241 cattttaccg tttgatttaa ggtaataagc tccttgccat gcattttttg cataagaacc
    39301 atctgatgtc aaataatacc aagcttgata agaagagtca taaatccatt cactctgtgc
    39361 cattttacca tcagctttca ggtaatagct tccctgccat gcatttttca ctagatttcc
    39421 atttccatca aagtagtacc aagcgccgtc ctgcttaacc caaccacttg ttgttgctga
    39481 acttgtgttg atttgaatag ccgttgactg ttttgcttta aaagcaccct taggagcatt
    39541 tttcaattcg caagccacac catcatgatc acggtctaac ttggcagaat aaccaggttc
    39601 tccctcgtga atatccgaat agccattcgc ccaagcttcc ttacagctcg aaaaatggat
    39661 gttttcttcc gccaaaactg gttgtgaaaa caaggctaaa attggcaacg tcaccagact
    39721 catttttaaa aatagacgtt tattcatttc tttctcccat aattatgata tcgatttcaa
    39781 tattatttta tcaaacttat ttcagcaatt caaggaaact tctggtcttt tctacaaact
    39841 cctttggttt tgccttattc aagacatgag ggccatcagg aatgatctga aactgcgaat
    39901 ctgttaacag tctatggaga gctttcatag aactaagatt cggtttatct ttgctgccac
    39961 aaattagtaa ggttggatag gagcaagtcc ctgctatatc cgttaaatca agtgtcttca
    40021 attcctcaga aactccgacc ataagagtct tgtctgctcc ctgtttttca aatactcttt
    40081 tgggaagtag tttaaaaatc agcaactgaa gataaaatag gatattccct gctaatttaa
    40141 gcgggcatcc tgacagaatc aaagctcgaa gatttggtaa atcgtaactg gaaagttcta
    40201 gtgtcagggc agcacctaag gacaatccaa tcaaaacaaa aggttctgtc tcttgagcta
    40261 ggtgctgata aactcgctct ttagcttgtt gatagttact aactccagaa ggaaataact
    40321 cgatagcctc agaaggataa tctgtcagta gattccgaac ttctttccaa gactctgctg
    40381 actgccctaa cccatgcaaa aatatcaatt tcatctagtt ctcctcaagg cttagttcat
    40441 acaagcctct cactgcatta cagccgtaaa tagcttctgc ttgggttaaa tctgccaagg
    40501 tcaagacttt ctcttctacc tgtcctgttt ctagcaaatg ctgacggtaa attcctggca
    40561 agattccaag tcggataggc ggtgtgtaga gttttccagc gattttcaga accaaatttc
    40621 ctatagaggt ttcaagcagt tctcctgact tattgtggta aatcttctct tgttctccta
    40681 ggctcaaatg cggtcggtga gtggttttaa agtaggtaaa ggattgattc aaagcagctt
    40741 cctgaaggca gacttgggcc tgacaaaagc ttgtactgag aggggttaat acttgacgat
    40801 tgacttctat ctctccagat ttgctaaggc tgattcgcaa gcggtaatct tgattagctt
    40861 cacaatcctg acactcttcc tcaatcttgt gtcccaagtc ttctgcatca aaaggaaagg
    40921 caaaataacg actagctttt ctcagtcttt ccagatgttg atcttcaaac agcaggttct
    40981 tctggctgat ttcccctgtc gtaatcagtt ggaagcgagc ttgtttacga taaagaactg
    41041 ctgccttttg atgaacctct cggtattcag attcccatgt gctatcccaa gtaatccctc
    41101 cgccaactcc ataaatggct tgacctttgt gaagttgaat ggtacgaatg gccacattaa
    41161 aaatccgtcg tccatttgga agcaagagac caatcgttcc acagtagact ccacgcggtt
    41221 gaggctccaa gttcttgata atctccattg tcgcaatttt cggtgcaccc gttatggaac
    41281 cacaaggaaa gagtgagcgg aagatttcaa caaggtccac atcctctcgc aactgactct
    41341 tgatggtcga agtcatctgc caaacagttg aatactgctc tacctggcac agacgctcca
    41401 cgtgctcgct cccaacttca gaaatacggt tcatatcatt gcgcaagagg tccacaatca
    41461 tcatattttc agagcgattt ttgggatcct gttccaacca actggcctgt tcaagatctt
    41521 cttggtcagt taccccacgc tgagtcgtcc ccttcattgg tcgtgttgtc aactcgcgat
    41581 cattttgctc aaaaaagagc tctgggctca tggaaatcac tgccatctcg tcatgttcca
    41641 cataggcatt gtagcccgcc tcctgctcta ccaccatacg attgtagatg gcaaaaggat
    41701 tggcacttaa cttttgcttg agttggacgg tgtagttgac ctgataggtg tctccctgcc
    41761 tcaagtgatg gtgtatctgg gcaatggcct tttcatagtc tgctgcagac gttacttcct
    41821 gccaatttga gggcaaatca atatcctcat aagtcagagg aataggggaa gtttctacgc
    41881 tatcatgaac agtaaaataa agcaggtact ctcccagtag gggatccttg tgaactgcta
    41941 atttttcctc aaaagcaggt gcagcctcgt agctgacata ccccaccaca taataacctt
    42001 gctcttggta gctttccact tgtgccagca aatctgccac ttcttctaca tttctcgttt
    42061 tcaactcttt aataggctgg gtaaaggtat atctctcccc taaagtccta aaatcaatca
    42121 ctgtttttct atgcatacct taagtatagc ataaaataag aaaaccctca tccgcaaagc
    42181 agatgagaga tttcgattat ctaaagatag aagttttaaa gctatctgtt tgttgaagaa
    42241 gtttcttata aacagcttct tttagtttta ctgtattagt catagatact gttttgtgac
    42301 cgtttgcttc ttgtttaaga gtttcagcat cttttttaac agcttcttta aatagtgtaa
    42361 gtaaatcatc gtatgatgaa acggaagaac catttacttc gaatgttgtt aatcctttcg
    42421 ttgctttatc tttaacttct ttgaaataag cttttttaaa ttcttcaata gtgttgaatg
    42481 tattattaga tattttcttg ataatatatt catcacttag aactgactcg ccatcttttg
    42541 tagattgttg tttatattta ttcgaagtat agcctaggaa tccgttaagg tatccgtagt
    42601 aaccccataa tctaaaggcg ttatgtttga atgaaacagc tccaggagca cctttactag
    42661 tattacctcc gtagataccg gctgtcattt caacccccac ataaggtgat tgatcgtatt
    42721 ggctaacgac ttcaggttta taaacacggt ttccaatttg tctattagtc attaactgtt
    42781 gatctattaa actatcaatt gatgtaatat ttaagttatc tttttcttca gttgttagat
    42841 ttcgaatttc gtcccactga tttaattggc tggcatctcg gaatttctta tctattttct
    42901 tgaaccatgc tccatttaac tctttattat tttgattaat aacagcatct gcctctaaat
    42961 gatcgacaag cattaaagca tcattgtaac cacgcatata tttatcgata tcatcacgtg
    43021 ttgtaagaga tttaggatct gtatcgtacc attgattacc atcattaggt tttttgaata
    43081 cggtattcag acctaatgaa ccatattcgt taaatccact tcctgggact ggtagttgta
    43141 acataccttg agcaaatgct tcagcatcag taccttcacg acgtccaaaa ccacccaaat
    43201 agattttacg atcgtttata tgtgttgttt catgagtata tacagaaata ccataatccc
    43261 caatcatatt tagagcaaca taacttacat cagaacgagg atccattgga ttatcataaa
    43321 gtgcagcata tgctcctgtt ccattataac cataatattt ttctataggt ccaaagaatt
    43381 ctctaagagg agtatataca ttgtcagtat tatatcgacc gtatttttca acccagccac
    43441 ctggcgcatt ataaccttcc cagataggaa tcacagtatc tcttagtaga tattgtttaa
    43501 cattatctgg aactagacga taccaaaaat catagtagtt tctgtaccca tcagcagcat
    43561 aatcaacaga tgctttaatg tcttctaatg atttttttcc taatttctca gcactaccaa
    43621 ttgcaattgc gttgtagtta gaggcaataa acatgtgtga tttagttata ttcaataatg
    43681 gtaaaatcat ttttctgtgc tgagctacgt ttaagttagc atatgctcta tatttagcat
    43741 ttttaatttc ttcgacctca gatgcgcgtt ctgcgatgta gacatggtct tttgtagcat
    43801 caataaacca atcattcata ttatctatat ttgtgaataa ttgtctatta taatttaaga
    43861 atacatctaa attacctgat ttagtatatt tagctaatac ttcaccgaat gcgtcgaatg
    43921 tacgtgaacc tttaatgttg ttctctttag agccgatttc aattaatctg tctaatacgc
    43981 taactttttc accatagaag tctggtttga ataacattaa ttctttaata ttaacatcac
    44041 cgaatttaac accgtagtaa cggtttaagt atgttaaacc taataatagg gcagctttgt
    44101 ttttctcgac tttatcacga agcatttgac gagcagctgg agaatcattt aactggtgtt
    44161 cttcattttg aactaatttt gtgattaggt ttgttaagtt ctttttaacg gctgtgaagc
    44221 tttcttctaa atataaatct ttgattgcat taactctata gtcacctaat cgatttaggt
    44281 gttgatacat tgtttgagat tgaagatcta ctggttctaa aatagatttt atgtcattaa
    44341 caagagtagt gttatctttt tgcacgatat tgggtgtata tttaattcct aggtcagtta
    44401 tagtatattc ttttacatta cttaaacctt cactgctaga agataagtta aagtaatctt
    44461 ttgtaccgtc tgcatagtga acaataattt tattagcttc atctaggttt gtgataaact
    44521 cattgttgtt catcgctgta acagaaagga cttctttagt atttagaggg tgttctttat
    44581 ttaatttatt accttggtat acaatataat ctttattgta gaatggtatt aatttttcaa
    44641 ggtttttata ggcttgatta tattcagcgt tgtaatcttg aatactagaa taagcttttt
    44701 cttcattaag ttttgcaaga ggagatagct cactttctaa tttatcagca gtaatattga
    44761 aagtagcaac tttagcatca gcttgttctt tagttaattg ttttattttt tgcagattgg
    44821 taaaattatt agctccactg ctagcgccgt tgactctata aatatcagat aagaattggc
    44881 gtgcatctcc gtcattaatt tcgtttgaac catatacttc ttcaccttta attactttag
    44941 cataggtaac aatatctttt ataactcccc aaggccaagt tttagctaca acaccaccaa
    45001 caaaacgagt atttttaaca tctaaagttc ctttagcaac cgaattggta acttttgact
    45061 tagttccata ctgatagcta tttaacatat atgtaaccaa aggaactagc atacttgcgc
    45121 ttgcgttagc ggcagtaatg ttagcatcaa cataagcttt attaacaaat cccatgtagt
    45181 tcgaaccagc aattcctccg actgtagaat tattaccaac agaattgata ttacctataa
    45241 atgctacgtt ttctagagca gcattttctt tgatattgtt tacaaatcca gcaacgttat
    45301 ttctggctgt tatcgttcca gttgctttga tgttttctat acgtgtggtt ccgttgattt
    45361 cattcgcaat tgtcgcgata ttatcttgat tagacacatt aatatcaata ttttcaaaat
    45421 ttatattttt aacagttcca gctttaatct tgtcaaataa tggatgttcc aattcagtaa
    45481 tagcaaattg ttttccttca gaacttaaaa gttttcctgt gaattcttta gtgatatatg
    45541 attttccatt aggaacaaca tttctagcgc tcattgattg tcccagacga tattcttttg
    45601 aaggatcgtt ttgaatagct tccactaatt ctttgaaatt ataatataca ttatcttcgt
    45661 ggactttagg tttttcaata tagtgaacgt attcttcttc aaatttatta tcagcagttc
    45721 tagagactaa attgtctgcg attgctgtaa ctttatatac atgtgttccg ttaaccgtag
    45781 tttcttctat atttttaaca gctagtaatg tagttttctg attatttgaa gttattttta
    45841 aataataatt gctcttatca tcaggaatag ttgttatcag tgattcatta gtttcttttc
    45901 cattttcgta tttgattaaa tctgtacgtt taatattttt aagctcaact tttttaagat
    45961 ctaattgaat attttgattt tctagagttt cagtttcttc accgttacct ctgtcgtaaa
    46021 tcatagttgt agatagggtg tattctttgt agtactctag gttcttaaat gcagcgctta
    46081 tagtttctgt tgttaccttg tcatctgtaa gaactacagt attaataact tcttctcctt
    46141 ttttcaactc agctgtgatt gatttgattt ttgttttgtt ttgattttct agagtatact
    46201 tagcaacagc ttcacgttcc aatattttct tatcggtact agtcaatgtt aatattggct
    46261 tttcagataa ttcaaccaat ttttcaatag ttgcagttaa tttttcaaca gcttcgttaa
    46321 cttcactttg tttagcatct gtattagctg caactttttc agcctttgta acttcagttt
    46381 ggaggttttg ccaacttcta tcactgtaat gttcttttac ctttgttttt gcatctgcaa
    46441 tcgtattgtt taattcagtt ttatcaacgt ttagagcgtc aatagccgtt ttaagtttat
    46501 ttgtctcgct atttacctca ggctgtttta caggctctga agcatagaca ccttttgcag
    46561 tttctaaaac aggtccaaga gcattgtaac ttgctgtaga ataatcagta ggagaaactg
    46621 aactagcttt atcaatttga ttatttaact cacttttatc aactggttct ttagtaccaa
    46681 taccctttat tttatcttct ggtttcggtg tttcctctac agccttctct tcttcaggaa
    46741 cttctggttg cttttctggc tcaactggtg ccgttggtgc ctgttcgtct tctcttggcg
    46801 cgactggttc acctgcttgt tcaacttttg gttcctctgt tggttctgtt tgtttttcta
    46861 cagcaggcgt ttcaactttt ggttgttcaa tagattgatt aacagtctcc tcttttggtt
    46921 ctacagtttc ttcagccttg gtatctggag ttgactcttc ttgtttcggt gtttcctcta
    46981 cagccttctc ttcttcagga gcttctggtt gattttctgg ctcgactggt gcctgttcgt
    47041 cttttcttgg cgcgactggt tcacctgctt gttcaacttt tgattcctca gctggtttgt
    47101 ctgatggttg actttctggc ttaactgcta ctttttcctc tggttttgac tcaacttctc
    47161 cacctacttc ttcaactgga gctggttctg ctgaatcttc tttcccctct tctactttag
    47221 gaagggtgtc gtcagtaggt tttacctccg attttggttc ttcctttgga ctttcttctg
    47281 ttttaggtgc ttcttctttt ggagcttcct ctgtctctac tacttggttt tctgtcctag
    47341 cttgctcctg atttgttgtt gattgaggag tctcaacttc gactacagtc acctctccag
    47401 gttttgctga ggtttcttct aaaacagtgt ccaagccaag cgttttgagg atgtcacctg
    47461 atagataacc aacatagcga tagccctcca tttcaacaac accctctcga ctagccagtg
    47521 ctagggtcgc aactgggttt acagcccctg cactaggaag aactaccaat cccatagttc
    47581 caactagaaa gacgctagca attttctttc tcttgtagat taaaagcaag ctcccaacag
    47641 tcagcaaacc aaaagctgtc aaaacagatg cttctgtccc tgtttgaggc aactgatctt
    47701 tttgatacac caaaccatat acaacttcat tcctgtcagg ctttcctgtc tgaattaaat
    47761 ctttagcttc ttgtgaaata atctctttat ttacatagtg ataggtggct gcgtccacta
    47821 cagaaggagc catcaaaagg cttccaagaa atacagagcc tacaactccc ttaatcttac
    47881 gaattgaaaa acggtctttt ttaaacactt ttatctcctt tattcattct caaaacttcc
    47941 taatagcatc ttgcggatag tgcgcacgcg cacctccgat taattttgga cgactagtca
    48001 gtgccgttac atgggcatga ccaatctctc tcaaaatagg gcgaatcgga acctgaacat
    48061 gcttgacatg catgccaatt gcagtgtctc cgatatccaa tccagcatga gccttgataa
    48121 attcaacctc aactggatcc tgcataaact taaaggctgc caactgcccc gaacctcctg
    48181 catgaagagt aggatggaca ctgacaattt ccagaccaaa ctgctctgcc acctgacgtt
    48241 caacaacgag agcccgattg acatgctcac aaccttgaac tgctaaatgg atacctctac
    48301 tacctagaat acccaagata gtctccacta tcagctcacc aatctcttga ctggattctt
    48361 tcccaatctg accacctagc acctcactag aagatagacc taaaacaaaa agggccccct
    48421 gtttcaaatt ggtcttttct aaaacatctt ccactacctg acgtgtttct ctttgaatct
    48481 gtgtctcgtt catctctgtt acctctgttg tcactcttct atcataccgt tttttcttgt
    48541 ttttagcaag atagacaacc tagaaagttt gcccaattac gcataaaact cccagaattg
    48601 actgggagtt agctagtttc tattctattt atatatattt caactttcgt tcctttttgg
    48661 ggtctagaat caatcttcat ctggtaattg gctccaaaat gaagtttgag ccgttgatcg
    48721 acattttgaa gaccaactcc cccacgtttg agttgacttt gactactatc accagcatct
    48781 tggaagccaa cgccatcatc ctcaatacgg atgaccaatc ccgaatcctg tttctggaca
    48841 gaaagtttaa tatggccctg accttccttt tccttaatgc catggtaaag agcattttct
    48901 acaaggggtt gtaggaccag cttgggtaag actaaattat caaaggcaac attttcatta
    48961 atttcgtatt ccagcttatc tccatagcgt tgtttctgga taaagagata ctggcggaca
    49021 tgattgattt cgtcagagag acaaatcaag tccttgcctt gattgagcgc caagcggaaa
    49081 taggttgcca aggacttggt cacctgcacc actcgctgac tatcatgaaa ttcagccatc
    49141 cagatgatgg tgtccaaagt gttatagagg aaatgtggat taatctggct cgaaagggct
    49201 tgaagttggt actgacgggt cgtttcttcc tggctacgaa tagctaccat caactgatca
    49261 atctgatcca acatggcatt aaattggcga gttacttctc tcagttcata ggcaccaact
    49321 tccttggcac gaagattttg agcaccagaa gcaatttcca acatggtttc tctcaaatcc
    49381 ttcaaaggag caatccagcg tttaagactg aaccacacta agcagagaca gacaagaaga
    49441 gatgtgacac tggccccaag caaggtccac aagagctgac tccgaacctg gtctaacttt
    49501 tccaatgatg acacgccaag taccgtccaa tcagttcctg caatcttctc ttgactgacg
    49561 taggatttgt gaccaggagt ataaccctga cctgtctcga tgtagggttt catagcctcc
    49621 attttgctag acgaactata aactgtgtgt tgaggatggt agacaaattc atggttttca
    49681 ttgataatga aggcaaagcc ctgctgcccc aactggagtt gattgagata ggcttccaga
    49741 gtttcataag aaatatccaa acgaagcaca ccaagattgg ctccctttgc atcaacaagt
    49801 tcttgagtga cagaaatgac ccactgacta tctgatttac gagctggagt caaaacaggc
    49861 atagctccct gatgaatagc cttttggtac caatcctcag ccatcatatc agaggaagtt
    49921 ttcatctgca cactgtcatc tgtagaaatg acctgaccag atttggtcac cagcacaaca
    49981 gttttcaagt ccttatctga cttcaagatg gtcaaaaaca aatctcggat tccctcgacc
    50041 ttgtcttgac tgggattctc agcataggcc agaacatccg tctgctgggt caaaccagtc
    50101 gaggtggttt ctagtttttt gatataagac tgaataaagt ggctagtctg gctgatggtc
    50161 gtttggctgt tgccctcaat ggtggcctca atggctgaag aacttgattg atagtagaaa
    50221 gttccaacca gagctaggag aatgagaaag accagaaaga tggaaataac cattctaact
    50281 aaaagagaag aacgcttcat cggtcttctc ccttcttaaa ctgacgaggt gtcacacctg
    50341 caatctgctt aaaacgttgg gtaaaatagt tcatatcttc aaaaccaacc ttctctgcga
    50401 tctcataaat cttcagatct gtagttaaaa gcaagagctt ggcttgttta acacgttctc
    50461 tcaccagata atcctgaaaa ggcaagccca actctttctt aatcaaggaa ctcagatagg
    50521 tcggactaaa acctaagtca ctggctaaag actttaaact aaattggcta tcagccagat
    50581 gagactggat tttctgggcc atgtttcctt caaacctatt agtcaataaa tcttgtaact
    50641 gctcttcttt ctcttccttg tctagttttt gtttgatttt ccccaacatt tcctcaatat
    50701 cctgacgaga aaagggtttg agcaggtagt cgtccacacc tagtttgaca gcagacaagg
    50761 cataatcaaa atcatcgtaa cctgttaaaa agaccaaatg aacctgagga taggtttctc
    50821 gtaccagact ggccaactgg atgccattta gatgaggcat gttgatatcg gttaaaatga
    50881 tatctggcac ctgcttttgg atcaattccc aagcctgcct tccattttca gcctgaccga
    50941 tgatttccat atcgtaggct gctacattga ccagtttagt caaaccttgt cttaccagat
    51001 attcatcttc tacgattaag attgtgtagg tcatgctctg ctcctttacc acttactagt
    51061 atcagtatag caaaattctc ctctaactgc ttaggaaaga cctcttatac tcaataaaaa
    51121 tcaaaaagta aactaggaag atagccacag gtttctcaaa gtatagcttt gaggttgtaa
    51181 ataaaactga cgaagtcagc tcaaagtata gctttgaggt tgtagataaa actgacgaag
    51241 tcagtaaccc tacatacggt aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt
    51301 attaatcaac ataatctagt aaataagcgt agcctttttc ttccatttgg tctttgggaa
    51361 taaagcggat agagaggcta ttgatacagt aacgtaagcc gcccttgtcc tgtggaccat
    51421 ccgtaaagac atgcccaagg tgagaatctc ctactcggct ccgcacttcc atacgcgtca
    51481 tattgtagga cttatcttcc ttgtaggtga caacatctgg actgatgggt tgggtaaaac
    51541 taggccagcc acaaccagac tcaaatttgt cttttgatga aaagagaggt tccccagttg
    51601 ctatatccac atagataccg gattcaaatt tatcccagta acggtttgag aaagctcgtt
    51661 ctgtttgatt ttcctgggta actgcatact cctcaggtga cagggtcttt ttcaattcct
    51721 catcacttgg ttttggatat ttgctggcat caatgacagg ataggccgcc tgattaacat
    51781 tgatatggca gtagccattt ggatttttct tgagatagtc ttgatggtaa tcctcagcca
    51841 ccacaaaatt cttcaagttt tccttttcaa ctgctagagg ttgatcgtat ttcttagcca
    51901 cctcatcaaa gacttggtta atcacttcca aatccttgtc atctgtgtaa taaacaccag
    51961 tacggtactg ggtccccaca tcatttcctt gtttattttt gctggttgga ttgataatgc
    52021 ggaaatagtg aagcaggatt tccttgagag aaatttgctt ggcatcatag gtgacatgga
    52081 cggtttctgc atgacctgtt tggttaatca attcgtactt ggttgtttct cctctaccat
    52141 ttgcatagcc tgaaacggca tccgtcaccc cgggaacacg tgagaaatat tcctccactc
    52201 cccagaaaca acctccagct agataaattt cgtgcaagtc tgcgtcttta ctaatttctg
    52261 tttttttcac tgcttttcct ccttggctaa ctgccgcctt ttcaatttgc gaggcatctg
    52321 tctgccctgc atttcgtatc aatagaacat agaaaccggt tatggctaga aaaaatactc
    52381 ctagcaacaa gaagattttt aacttatcat tcataagacg cctcctaggc taattccttc
    52441 aaagtttgca aaattgcatc tttttccatg aatcctggat gtgttttgac cagcttgcct
    52501 tctttgtcta taaaggcttg ggttgggtaa gaacggacac cataagtttc caaaagtttg
    52561 cctgatgggt caactaggac tgggagattt ttataatcca atcccttata ccaattctta
    52621 aagtccgctt cagattgctc tcccttatgt cctggtgaca ctactgtcaa gaccacatag
    52681 tcatcaccag cttctttagc aatctcatcc gtatctggaa gactagccag acagatggaa
    52741 caccaagaag cccagaattt gagatagact ttcttgccct tgtaatcaga taaacggtag
    52801 gtcttgccat ctactcccat caattcaaaa tcagccacct ctttcccttt agctgcgctt
    52861 gttttactag ctgtctgctc cgtcttcatt tcatctttcg tttggtgttc actagtcacg
    52921 gacttgcctg aacaagccgt caaacaaagg agcgaacctg ctccaagaac acatgtttgc
    52981 cattttttca tattgatatt cctttccatt ttattcaaat aattgactta aaattgaagc
    53041 atttccaaac agaaccaaga atcccatcac aataatgaga aaaccaccca cttttttgag
    53101 gattccgaga tagggatgaa gttttcggaa atgtttcaaa acataactag aggtcagagc
    53161 tagaagcaag aatggtagcg ccaagcccag cgtatacacc aacatgagac cagctccctg
    53221 ccaagctcct gaaccacctg aagccgccaa ggccaaaaca gaccccagaa ccggccccac
    53281 gcaaggcgtc caagcaaaac taaaggtcaa gcccaataaa aatgcctgac tatagccctt
    53341 accattttgc ccctgtcctt gcagttgtag cctcttttcc ttataaagcc ccttaaagtg
    53401 tagaatctcc atttggtgca aaccaagaag gataataatt gccccagtaa gatattggaa
    53461 ccaagaagca taaagcaaat cgcctaaaaa accagctcca tagcccaaca aaataaatat
    53521 aaaggaaatt cctgctataa aggccagagt tcgtaataaa ctagtaactg agattgaaaa
    53581 tttgccgcta gaagcctgag caccatcctt atcatctagt aacactcctg tatagaccgg
    53641 taacaaaggt aagatacaag gagaaaagaa ggatagaatc cctgccaaaa agacacttag
    53701 aaaaaagaaa atatgaccca taaagttcct cctatcattt tattgataga tttattatac
    53761 tccttccatt ttcgaaaaaa cagggacaat gataggggaa aataggaatt taatcagatg
    53821 atttagaaat cttggacaaa aactatacaa aaaactgtca aagcacaaaa gcgcatagta
    53881 tcaagattct ataaagcctt gatactatgc gcttttgtaa tggataaata gttagtcttt
    53941 tttaaagacc tgatctttca aactctgcat actggcattg atcaccgcgc ctaggataac
    54001 aattttagca atcaagataa accaaaacat cataacaaca agaagaacgg aacctaaaat
    54061 tcggacatcc accaaatgat ggacatagta attgagataa ctagagaaca gagttagtac
    54121 acctaaaatc accaagagaa caaaggcact gcctggtagg gtatagctaa ttttcctgtt
    54181 agatagattg ggaagaaaat aataaagcat gaccaagata gcaaagagga gggcgtaaat
    54241 cagaggacct gccaaccctt gtaaagcctg atagataatg ccatcttttg tccaataatg
    54301 agcaagtaaa gccaaaatca tctgaccaaa taagatcaaa aacaaggcaa acgcaaagag
    54361 gaactgcaag ccaaaactga ctaggagact tagcatctga tgggaaataa gtccacgact
    54421 cttttcgacg ccataagcct tgttaaaagc tttttgcaag aaatttatag attttgaaaa
    54481 actccataac gccgataaaa cagaaaaact caataaacct gttgaaggtt gcgtcaagac
    54541 ttctctggct attttttcca caccttcata gaggcttggg ggcaggacgt ctttcataaa
    54601 gcccagaaat tctcccacag gaatctgaaa ataggggagg atattgacca ccaccaaaag
    54661 cagggggaaa atcgaaatca accaatagta ggctactgcg acactggtca actcactatc
    54721 tgatgcttga taataatgca aaaaagcttt taataaaggc ttgtctatca gctctttcca
    54781 ccactttttc atgtcatact ccttcattta taatcttata ctcaatgaaa atcaaagagc
    54841 aaactagaaa gctagccgca agctgctcaa aacactgttt tgaggttgta gataagactg
    54901 acgaagtcag tcacatacat acggtaaggc gacgctgacg tggtttgaag agattttcga
    54961 agagtattaa ctaatttctt cttaccaatt ccaccatatc atacggcagg gtattggcag
    55021 cttccttcaa ggaatagttc tctaagttat ttacattttg tcgtaatttc ttggcatact
    55081 tagttgtaat taatcgtttt tcttcgtatt cgaaaatcaa cttgcgctcc agataatagc
    55141 ctctcagcat ttcattgata ttgttgggtt tgacacgatt gataacccgt tcgacaaagg
    55201 caccactgct gataatagtt gtttctcgaa gacgagactc ctgcataaaa ctaatcaaag
    55261 agcgtctgta gactcccttc aggttttcca aactttcaat aatcatctcc gtattggcaa
    55321 gatagagctc tgcaatttgg tcataatcaa gagcacggag acggctttgc tccttgtcct
    55381 tccagctacg gaaggtcttt ccaagagtaa aaacttcatg aaggagaaaa cgtaaaatcc
    55441 tcaaggaaac aagaaaataa taggtcagtc ttgaggcaag tttacgattg attccttgtt
    55501 ctatattttt cagataacgt tggtaaactc ggtaagcacg attgctaatg ttcccctctt
    55561 cataggcctg ttccaaacca tcactttcaa tactaagaat caagagtttc aaagcagccc
    55621 agtcttcttg atcatcctgg ttttcttggc ttaaaatgag attttcaata cgtccatgat
    55681 aattgtcaat agccgcatag aggggaagtt tatttctggt gtcttccaac tctttttcca
    55741 actctagcgt tacttcattc aaaatggcga tatgcatgag ataatccttg ctttcttcct
    55801 cttcatcaga aagatgaggc aagatcaaga gacctgttaa aaagctgaca agcgtcacac
    55861 ctgcaacaag gaaaagcaaa agaggatact cttgttctag attacttggt atcaagagaa
    55921 tcgtagcaat cgacaccgtt cccttaacac ctgaaaaggt caagagaaac atgtccttca
    55981 tatacttatt tagctttttc ttgaggcgtc gggttctata ggcataatag ccatagatca
    56041 taataaaacg aatgacaaag aggacaaagg taagggcgat gagagatagc aataaaagta
    56101 gaggattata gattggattg gtcaagatag gttctgctat catttccaac tccatcccta
    56161 aaatcacaaa gacagaaccg ttgagcataa aggtcactgt atgccagacc gtctcggtca
    56221 ccgtatccac ttgggcttcg aggagcgtga ttttcttgaa acgacttgcc tttaaaattc
    56281 cagcaactac gacggcaata atccctgaaa catgaacttc ttctgccaga aagaaggtca
    56341 ctagaggcaa acttaattct aataaaagtt cactggcaat atccgttgcg cgcacactta
    56401 gcaagaaggt atggaggaag cggttggtca tggctgttaa aaatccaatt aaaaaaccgc
    56461 ctaggattga aaagatgagc gaactgctag cttgccccag agaaaaagct ccagttgtcc
    56521 aagctgtcaa agctacctga aaagccacca aaccagaagc atcattcaag agtccttcgc
    56581 ccttaagaat attggacacg cgcttaggaa agctaaaacg ctccgaaaga gaggcaaagg
    56641 ccaccaagtc cgtaggacca agggctgccc caacagccaa gcaagctgcc aagggaaggc
    56701 tgaaccaaag aagatgggcc aagccaccca aactcagggt cgagataaaa atcactggaa
    56761 atatgagata aacaatgatt cgccagtgtt ttaaaatagc cgtaacatct gcttcttcag
    56821 cctctcggaa aagcaagggt ccgataacca gggccaaaaa caactccgta ttgaggtgaa
    56881 agtcggtatt gggtaaaaag agaccaatca caattcccaa aagaatttgc accaaaggga
    56941 gaggcaaaaa gggcaggagc ttattggttg tacttgagac aatcaaaacc agtaaaaata
    57001 ggatgaggta aatcagtaat tccacgcacg tcctccttaa tcttttttac aacaggattc
    57061 aaatatctcc ttctgctctt tgattttttg gtcaatcttg gaacagtctt tgtgctcaat
    57121 ttttctctgg caccgttcca tttcaagagc aactaatttt ttcttgattt taagcatttt
    57181 tttgctcata tgcgcttggt ctagcacgcc caccgatcgt tcgtggtggg ttgattcaac
    57241 aaaattctgg cgcatggcat ccagcttttc gtgtaggtat tgtttatcca tgtctgtatc
    57301 tctctaattt ttcaatcatc actaaaaacg gcgggttgtt gacttggttt aaagttcggt
    57361 aaatggcagc tgtgtactct tgttggttca actggattac aaaatccaag acagcatctc
    57421 tctcgaggtc gcctccttca tgaccatagt aaatcataat agcaattcgt ccacccttga
    57481 caagtaagcc acatagcttt tctaatgcct caatcgttgt ctgcggtcgg gtgatgacag
    57541 acttatcagc tgacggcaaa tagcccaaat taaaaatccc tgccttagct tttgtcacaa
    57601 actggtccag tgtctcatgg ccttgcaaga ttaactgggc atttgtcaag ccagcctgat
    57661 gcaaacgctc ttgggtcttt tccaaggctt gcttctgaat atcaaaggca tagacttgct
    57721 tggctagctt ggctaaaaaa agcgtgtcat gaccatttcc catagtcgca tccactacga
    57781 catcctcttt tgtcacgacc tcagccaaaa aatcatgtgc catctcaagt ggtcttttca
    57841 ttttcaaact cctgttttac agccttgcat ccttgaacac ttccacgacg tcgcatctcc
    57901 atctcaatgc tgttgagagc ttcccattta ttgaggctcc acataagccc aatcagcata
    57961 tccctaggtg catctcctgt gattcgatgg atgacgatat gtttgggaat gatttccagt
    58021 tggtcacaga tgaccctgac atattcgtcc tgactcatca attgtaaacg tccctcatgg
    58081 taatctcgtt gcatacgagt atttgtcata agatggagca aatgcagttt aatcccttga
    58141 atatcgttat tcgtgacaca acggcggaca ttttcaacca tcatctcatg ggtttcacca
    58201 ggcaaaccat taatcaaatg ggaaacaatc tcaatcttgg gatactttct caaacgcttg
    58261 accgtttcca cctacaattc ataagaatac gcacggttaa tcaggtcaga agttgcttca
    58321 taagtagtct acaagcccaa ttcaaccgtc acatgcatgc actccgataa ctcagccaaa
    58381 tattcgatgg tttcgtctgg taaacagtct gggcgcattc caatattgat tcctaccaca
    58441 cctggctcat tgatagcctg ttcataacgc tctcgaataa cttccacctt ttcatgggtg
    58501 ttggtaaaat tttgaaaata aaccagatac ttctgaacat ccggccactt acggtgcata
    58561 aagtcaattt ccttataaaa ttgctcacgg ataggcgcat ctggggctac aatagtatct
    58621 ccagaacctg aaaccgtaca aaaagtacag cctccatgag ccacagttcc atcacgattg
    58681 ggacagtcaa attccgcatc aatagggact ttaaaagtct tttctccaaa gagttttcga
    58741 taataatcat tcaaggtatt ataagatttt ataactttca ttataacaaa aatcacccac
    58801 aatctcaaaa gcctgacttt cctataaatt cctctgtttc tcgtttccat tagctttttt
    58861 ttatgataca atatgggtat gattttaatg aaattagcat ctattttatt attgatactg
    58921 accttagtcg tctgcattat cctaaccaaa ctttttagat taaaaaaact aggacgaaac
    58981 tttgcggatt tggcttttcc ggtcttggta tttgaatatt acctgattac agctaaaacc
    59041 tttacccata atttcctccc tagactgggg ctagccctct caatcctagc cattattctc
    59101 gtctttttct tccttttgaa aaaactcagc ttttactatc ctaaattcat caaattcttc
    59161 tggcgtgcag gattcttatt aacccttatc atgtatatag aaatgattgt tgaattgttc
    59221 ttaatgaaat agtcgaatcc ctaagcattt tctagggatt tttgctttct ctacaaaata
    59281 gtatagacaa taacactata caattttata caaagaaaag agtctgggac aatagtctct
    59341 tatctccaaa aaaagcaacg gatttgccgt tgcttttttt gcatggttac gatagtcttg
    59401 gtaaaataga attgcccaat aaaccattta gaaaggctat cccatgcata ttcactataa
    59461 cacaaatcaa acaactttac cactagaaat cagttccttc ttaccacaag accatctcgt
    59521 ctttactatt gaaaaagtgg tgaatacctt ggaggaacat cacttctacg ccttctatca
    59581 tgcctttgat cgcccgtctt atcaccttaa aatgcttgta tctactcttc tatttgccta
    59641 ttcacaaggg attttctctg gtcgaaaaat tgaaaaatgg aagagttagt gaccttagat
    59701 tgtttgttta ttgacggaac taagattgaa gccaatgcca acaagtatag ttttgtgtgg
    59761 aagaaaacga cagagaaatt ctccgccaaa cttcaagaac agatacaggt ctattttcaa
    59821 gaagaaatcc tccccttctg attaaatatg ccatgtttga taagaaacaa aagagaggac
    59881 ataaacagtc agctaaaaac ttagcgaatt ggcactataa tgacaaggag gatagctaca
    59941 cacatcctga tggctggtat tatcgttttc accataccaa acatcagaaa acacagacag
    60001 actttcaaca ggaaatcaag gtttactacg ctgatgaacc tgaatcagtc cctcaaaagg
    60061 gactgtatat gaacgaacgc tatcaaaact tgaaagctaa agaatgtcag gcgcttttat
    60121 ctcctgaagg tagacagatt tcgctcaacg caagattgat gtgaaacctg tctttgggca
    60181 gataaaggct tgtttgggtt acaagagatg taatctgaga gggaagcgtc aagtgagaat
    60241 tgacatggga ttggtactta tggccaataa cctcctaaaa catagtgaaa tgaaataaga
    60301 ccaggacaaa tcgataagga cagtcaaatt gatttctaac aatgttttag aagtagaagt
    60361 gtactattct agtttcaatc tactatacaa taagagaacg actcaaaatt aaaaagctag
    60421 agttccgcaa ttggaaatat ctagcttttt tgtggttgag aactattttg ttccagactc
    60481 tttatcttct atttaggaca agagtttttc tttggtcttt aatgataaag aaggtatcaa
    60541 aatttctagt cttctttttt acctttagta actactaatc ctgcactcaa acctagaaga
    60601 gctaaacctg ctgctactgc tgcttggctt gccgcactac ctgtatttgg taactgggct
    60661 ttattagttt gatcagcttc acttgaatca attggttttg tatctgcttt ttctgacact
    60721 tgtggttttt tagcttcttg agctactggt ttggttccaa ccaagacgat gcggtctgtc
    60781 ggaacttcta ccacttcacg gagtttttct tccttacttc catcaggatt aatcactgta
    60841 aagatacgtt cttttccaac ttttccttct tgttctacac gagtttcacc tagatacagt
    60901 gttgaatctt ttttctcaac tgtcttgtag gccaaatctt tttcaacaaa ttcgagtttt
    60961 ggaagatctt cttgtacagc agaaactggt ttttccttag tcaactgaat acggtattcc
    61021 ttgacttgtt ttccactttc tgaaacgagg cgaacaagta ctggaaggct atcttctcca
    61081 ctatctacca cagttgaagc tacttgattg ttttcttcaa ctgagacttt tggccgttga
    61141 cctttatagg taatttgata gtcttgacga ttttcagcga aatcagcaag ttcttttcca
    61201 tctacaagaa tctttgattg cgtgctttct tgaggcaatt cacttggtgc aaggaaggtc
    61261 atctcaatca tcgcaacacc gctcttgtca gctttacgct ccatacgcca tctcatggct
    61321 ttggctttga cagctttaaa tgttacgttg atttcatcac cagctgcgat gtctttatcc
    61381 gcacgataag gcacagcttc ccaattttct ggattgttaa atggatgtcc agattcgtag
    61441 gcttggtagt ttgaatagta ggtaggtact tcaaagcctg ggccgacata gcgttctaaa
    61501 acgagtttag atggtgcatc cgtaccacta tctgcaaaga agtgaagttt ggcttgagca
    61561 acagtccgtt ctacaatctt accattttca cggaagatca cacccgctga tacttctgga
    61621 ttagaagatg gtgttggtga ccagtttgtc caacgacgat tttctgaatg atctccgtca
    61681 ttgagatagt caacgcggtc atgagagttt ttgtcaatat cattggttgc tgaagcaaag
    61741 gcctggttac tgttttcatc atagttaggg ttatctgaaa gagtctcacc aagtttgtct
    61801 gtcactcgta cagtgacctc agcaacaagg ttactaccaa ggacacggcc tcgaacagta
    61861 aattgacctg cttttgtcag attttccgct ggaacttctt cccattcaac tgtcaggtct
    61921 tttgtttcgt agccgtcttt acctgtgaag taaactggaa ccttagtcgg caattcaagt
    61981 gcttgaccta cttgtagcaa gcgagcttgt ttaaccgcag caactggttt atgagaaagt
    62041 aagttcttat ccttagtgaa gtgcagacgg tattctccta agatgtcgcc attttcagct
    62101 ttcgcgatga cacgaactgg ctcaccttca cgaacgcttg gaacgacggt agcgagacca
    62161 ttgttgctaa catttgctgt gactgccgga acttttccat ctacagactc aaggtagtag
    62221 tctgtcaaat cagggttgaa gtttgctaag tctttgccgt caacttggat tcttgtttgt
    62281 ccttgtttgg ctgccgcaac ttgtttcgca aagatttgta cctctgtgat agacgttcca
    62341 cgcttgttat ctgctttaac catgcgaata cgaatagcat aggtttcaac tttatcaaag
    62401 ctaaagtggt tcatttctcc agccttgagt tgagcagggg cttttagatt agtaactggt
    62461 ttccagttgg cagaatcatt aaagacatgg tcctcattac caacaaaact agggttttta
    62521 ggagctgttg ggacagtctt accaacataa tactcaatca cataagactt cggtgcacca
    62581 actccatggt cttcgtggaa tccgacactt agattatcaa cggagcgttt gctcaagata
    62641 cctgaatctc caaacagaac accgactgaa gcttctggat tactacgatt ccagtttgtc
    62701 caacgattgg ctggttggtt attgtaggaa atgagcttgt cattaacatt tgaaactggg
    62761 tcgcttggat ttgaatctga agcaaaggca agtggcaatt ctgaaccggt ccattggtca
    62821 gaaatgtttg caccttgctc agtttgagca gatacgcgaa catgaagttt agttgttaat
    62881 tgagtacctt ctaagcgacc attaactgta aagacacctt ccttagcgta ttgctctgga
    62941 cgaatcgcat cccatgcaac cttagctgat gaaacgtgac catttgaatc atatgtccga
    63001 acactttctg gtaattgtgg tgcttctgcg attggagttg tcacactgac ttcttcaact
    63061 gaaacgatac cttctacaga gacttttgca cgcgcttcaa ggtcaattcc ttcaacttta
    63121 cctagtactt caaatgtttg ataggagtct agtttttctt tcggaatagc ttgccaagtg
    63181 actttatgag ttttagggaa acctttgtca tactcaactg ttactgttgc tggaagactt
    63241 ggttcctgat gcaaatctgt cactacattt acaggacgga tggattgcgc aatcttcttc
    63301 tcagtattgg cttggatagt gagttcaact tggcctttag ctccctcata ttcagcgttc
    63361 agagtgactg ctcctggctt atgcaactca agcattcctt tacgaattgc gacttcccct
    63421 tcaccacttg tagagaaggt tactttatca gctggtaata cagcttgcgt tccatcttga
    63481 tagtgagctc gaaccgacaa tttgacagtt tggtcttctt tgagactgtc agctttttcc
    63541 acttgcaagc tcaagtgagc aatttttggc gcttcttcaa ggaattgaat tgcataggtt
    63601 tgaagagggc caccatcttt aggctgaata aagatgctcg cacgcatgcc gtttgctgcg
    63661 cttgcttgaa gaactgtaac agctgcattt ttagcacttg ctgtgacttc tggcaactta
    63721 gctccataag caagagtgcg gtattgcatt ggtttttgac tagtaagacc tgtgacagct
    63781 tcaccaccaa ccgttacagt tggtactgca ggtgccgcag gattgccttc ttctaccaca
    63841 agggttgcat gaattggttg accttctaaa taaccggtcg cttgaatacg agaacctgga
    63901 attgctaact tagctttatc ttcttcggca atctcccact tgtccacttc atactcttca
    63961 acacttccat cagtcaaaac ataggaaaca gatttgtcta cagaattcaa gtcagtattt
    64021 ggagcaatac gtttcacaac tggtagctct gatttaagag caatcacttc tacacgagct
    64081 tctacttctc gtccgtcagc catacctttc accgttacaa taccaggctt gctcacatct
    64141 actgaagacc aggttacagg acgttctgca cggctaccat cactgtatac aaacggaaca
    64201 gtggtaggca tttcaggtgc ctctccaata atggtctgta cttttggcac ttctgtcccc
    64261 aaaacagtct tctcttgtcc ttctttttta ccagtaaaga cagtgacttg actagatttc
    64321 aagagatctg aatgggctgt cagtgtgaat ttccctgctt gttcagttga tttgacaatg
    64381 gcaacacctt taccattaaa tgctttacga atccaagaac catctgcttg cgccttatag
    64441 cgttcacggc tggcttgttc tccgttatct acaccgacca gttgaccttg gccatgcaat
    64501 tggaagcgaa ccagattatt agcagttgga accacattcc cctggctgtc aacaatttca
    64561 tagtagatgt aagtcaagtc ttttccatct gctgcaatcg catggtcttc cttaataaga
    64621 cgaactgccg ctggcttacc agcagtcgta atcttatctc gagcaatttc cttgccagat
    64681 tcatcacgag caattgcttc caaggtacct ggttgatagg caactttcca ttcaagataa
    64741 agttcattag catttgcacc ttcttggtaa gtccgcccat cgctggtttg ttttttattg
    64801 aaagtcttaa gaccaagaga ttttccattc aagaacaatt ctacactaga agcattcgaa
    64861 taagcacgaa ctggaatctt accttctgag tcagctactt tggatgctaa ttctttgttt
    64921 tcccagttcc agtgaggaag aaggtgtacc atcggtttct tcttaacaga aacccattgg
    64981 ctttggtaga ggtagaagtc atgttttgga atgccggctg tatctacgat accaaagtaa
    65041 gagctcttaa caggagtttg attttggttg tgccatggtg taggttcacc aatatagtcc
    65101 gtacctgtcc agataaactg tccagcatag ccagcgttgt cacggtcaaa agtccatgaa
    65161 gcggttgctg ttttccccca accaacacga tcattcccat agtcagactg ttcataatta
    65221 cgctcaggtc cattgctatg tttcaattca cgttcagggc gatagtaact tccacgtgta
    65281 cgggtagctg aagatgtttc tgatccataa atcaaccatt ttggatgctt agctctaagg
    65341 gctttgtaat tatcttcaga atagttaaat ccaacagcat cgagttcatc agcaattttc
    65401 tcatgccctc cgctaccatt accgaaacgg aatttatctg ctcccatggt aacatagcga
    65461 gtcttatcaa catccttgat aaccttgacc aaacgtttaa cagttgctaa agagtgggca
    65521 tcaccattag cttcacctat ttcattacca attgaccaca tgaagatagc agggttattt
    65581 ttgcctcttt cgaccatggt acgtaggtca aaatcagacc atttttcacc ttttcgagct
    65641 tctgggtgag tggcatcttt ttcaaagaaa cgtccatagt cataaggttt cttgccacca
    65701 taccaagtat caaaggcctc ttcctgaacg agtaaaccta gttctgctgc gatttgcaag
    65761 gtttgctcac tagcagggtt gtgggttgta cggatggagt taactcccat ctccttcatt
    65821 tgtttgagac ggcgatattc tgctttatag ttttcttctg ctccaagcgc cccatggtcg
    65881 tggtgcaagg atactccatg gaatttaata cgttcaccat tcaaagagaa accttcattt
    65941 ggagtccagt gatagtaacg gtaaccaaac aaatccttct tagcatcaac caattgaccg
    66001 tcacggtaaa cacgcgtaat caattcgtac aaggcaggtt tgtcatttaa aacggtccag
    66061 agttttggtc tttcaacttc taaaatcgca tctaggcttg ttgattcatg tgcttttaag
    66121 gtacgactcg ctgtacgaac taagcctgtt acagcatgac cacctcgttc aacgatttga
    66181 tattcggcta caagttcatg gtctttgtcg tccgtattga cgattttgct ggtcacatga
    66241 gtttcaacct tgccatgttg ttgttcttca agttttggtg ttaaaatagt tgtcccattt
    66301 ttctcaacat gcaccttatc tgtcacttgt aaagtcacat cacgatagat accacttcct
    66361 gaataccaac ggctacttgg ctgtttgttg actgcatgga cagcaatcac attctcacga
    66421 ccatctttat gaaggtattt ggtgatatcg tatgagaact ggttataacc atttggataa
    66481 tgccccacta actgaccatt gacataaact tgagaatcca tgtagacgcc atcaaaagta
    66541 aggcgaacat ttttcttgag gtctttttca tctagtttga aagtcttgcg ataccaagct
    66601 tccccaccgt tgagctgtcc accttcattt tgtgcaggag attcatgatc gaaatcgtta
    66661 aagatactcc agtcatacgg taaatctaat tttttccacg tagatacgtc tgcatcaggt
    66721 ttaatggctt ccttagaatt tgcattgagt ttaaagtacc aattttgatt aaaatccact
    66781 ttcctgtctt caatcatttg attcacttct tcatttgtta cagctttagc atcttccttg
    66841 agcggttttt cttgacttga agcttgtgat tctatccttg gagctttttc ttccggttta
    66901 gcagacactt tttcctcttt tggagttacg gcttcatctt ctttcttctc agatgcaata
    66961 gcctcagttg aactaggttc actttgttct gtcctttcaa ctacattttt agtttccaaa
    67021 gctttatcag ccttttcttc tactatcatt ttttcctctt taggtttctc agcagtatga
    67081 gtaataagtg tttcatccgc ataaactaca gattctccag ctatatttcc tcctaataga
    67141 actgcacaag tcccaatcat tactgagcaa gctcccacag caaacttacg aatgctataa
    67201 actcttttcc gattccaatg gcctttcccc ataaaaccct ccttatatta tatttagtgc
    67261 agttagctac taccaaagcc caagtggtat acatggtatg acaacctagt ttcaacaatt
    67321 tacactctgc gaaaatccaa ttcaaacttc gtcagtgtcg ccttgccgta gatatgatt
//
LOCUS       DAVIME010000005        65453 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVIME010000005 DAVIME010000000
VERSION     DAVIME010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 65453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65453
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.005"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            43..1266
                     /locus_tag="VV588_000344"
     CDS             43..1266
                     /locus_tag="VV588_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU7082744.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1916..2086
                     /locus_tag="VV588_000345"
     CDS             1916..2086
                     /locus_tag="VV588_000345"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU7082745.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            2698..2982
                     /locus_tag="VV588_000346"
     CDS             2698..2982
                     /locus_tag="VV588_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082746.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            2975..3223
                     /locus_tag="VV588_000347"
     CDS             2975..3223
                     /locus_tag="VV588_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082747.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLHATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            3319..3537
                     /locus_tag="VV588_000348"
     CDS             3319..3537
                     /locus_tag="VV588_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082748.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LESFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(3905..6229)
                     /gene="pflB"
                     /locus_tag="VV588_000349"
     CDS             complement(3905..6229)
                     /gene="pflB"
                     /locus_tag="VV588_000349"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU7082749.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            6577..7638
                     /gene="dinB"
                     /locus_tag="VV588_000350"
     CDS             6577..7638
                     /gene="dinB"
                     /locus_tag="VV588_000350"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU7082750.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILCAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(7785..8630)
                     /locus_tag="VV588_000351"
     CDS             complement(7785..8630)
                     /locus_tag="VV588_000351"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU7082751.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(8661..8798)
                     /locus_tag="VV588_000352"
     CDS             complement(8661..8798)
                     /locus_tag="VV588_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082752.1"
                     /translation="MRYQTHYQLKQKLWLDPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            8885..9856
                     /locus_tag="VV588_000353"
     CDS             8885..9856
                     /locus_tag="VV588_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU7082753.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALKLLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCLD
                     IIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPR
                     SIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILA
                     EIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACARF
                     SPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(10055..11944)
                     /locus_tag="VV588_000354"
     CDS             complement(10055..11944)
                     /locus_tag="VV588_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU7082754.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            12082..13647
                     /locus_tag="VV588_000355"
     CDS             12082..13647
                     /locus_tag="VV588_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU7082755.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            13647..14411
                     /locus_tag="VV588_000356"
     CDS             13647..14411
                     /locus_tag="VV588_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU7082756.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(14610..14825)
                     /locus_tag="VV588_000357"
     CDS             complement(14610..14825)
                     /locus_tag="VV588_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082757.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(15696..16946)
                     /gene="ilvA"
                     /locus_tag="VV588_000358"
     CDS             complement(15696..16946)
                     /gene="ilvA"
                     /locus_tag="VV588_000358"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU7082758.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(16996..17352)
                     /locus_tag="VV588_000359"
     CDS             complement(16996..17352)
                     /locus_tag="VV588_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU7082759.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(17590..17826)
                     /locus_tag="VV588_000360"
     CDS             complement(17590..17826)
                     /locus_tag="VV588_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082760.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(17933..18955)
                     /gene="ilvC"
                     /locus_tag="VV588_000361"
     CDS             complement(17933..18955)
                     /gene="ilvC"
                     /locus_tag="VV588_000361"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU7082761.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGSRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(19021..19497)
                     /gene="ilvN"
                     /locus_tag="VV588_000362"
     CDS             complement(19021..19497)
                     /gene="ilvN"
                     /locus_tag="VV588_000362"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU7082762.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(19490..21190)
                     /locus_tag="VV588_000363"
     CDS             complement(19490..21190)
                     /locus_tag="VV588_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU7082763.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(21391..23058)
                     /locus_tag="VV588_000364"
     CDS             complement(21391..23058)
                     /locus_tag="VV588_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU7082764.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(23061..23426)
                     /locus_tag="VV588_000365"
     CDS             complement(23061..23426)
                     /locus_tag="VV588_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU7082765.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(23583..23771)
                     /locus_tag="VV588_000366"
     CDS             complement(23583..23771)
                     /locus_tag="VV588_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU7082766.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(23887..24063)
                     /locus_tag="VV588_000367"
     CDS             complement(23887..24063)
                     /locus_tag="VV588_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU7082767.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVMQDLI"
     gene            complement(24174..24372)
                     /locus_tag="VV588_000368"
                     /pseudo
     CDS             complement(24174..24372)
                     /locus_tag="VV588_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(24800..26344)
                     /locus_tag="VV588_000369"
     CDS             complement(24800..26344)
                     /locus_tag="VV588_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU7082768.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNKRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            26557..26859
                     /gene="gatC"
                     /locus_tag="VV588_000370"
     CDS             26557..26859
                     /gene="gatC"
                     /locus_tag="VV588_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU7082769.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            26859..28325
                     /gene="gatA"
                     /locus_tag="VV588_000371"
     CDS             26859..28325
                     /gene="gatA"
                     /locus_tag="VV588_000371"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU7082770.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLSAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            28325..29767
                     /gene="gatB"
                     /locus_tag="VV588_000372"
     CDS             28325..29767
                     /gene="gatB"
                     /locus_tag="VV588_000372"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU7082771.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNTEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            29896..30456
                     /gene="efp"
                     /locus_tag="VV588_000373"
     CDS             29896..30456
                     /gene="efp"
                     /locus_tag="VV588_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU7082772.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            30478..30867
                     /locus_tag="VV588_000374"
     CDS             30478..30867
                     /locus_tag="VV588_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU7082773.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            30860..31282
                     /gene="nusB"
                     /locus_tag="VV588_000375"
     CDS             30860..31282
                     /gene="nusB"
                     /locus_tag="VV588_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU7082774.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQMVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(31332..31568)
                     /locus_tag="VV588_000376"
     CDS             complement(31332..31568)
                     /locus_tag="VV588_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7082775.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(31581..32054)
                     /locus_tag="VV588_000377"
     CDS             complement(31581..32054)
                     /locus_tag="VV588_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082776.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(32072..32257)
                     /gene="briC"
                     /locus_tag="VV588_000378"
     CDS             complement(32072..32257)
                     /gene="briC"
                     /locus_tag="VV588_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU7082777.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(32416..33183)
                     /locus_tag="VV588_000379"
     CDS             complement(32416..33183)
                     /locus_tag="VV588_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU7082778.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(33180..34046)
                     /locus_tag="VV588_000380"
     CDS             complement(33180..34046)
                     /locus_tag="VV588_000380"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU7082779.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(34083..35450)
                     /gene="accC"
                     /locus_tag="VV588_000381"
     CDS             complement(34083..35450)
                     /gene="accC"
                     /locus_tag="VV588_000381"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU7082780.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVKKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(35462..35884)
                     /gene="fabZ"
                     /locus_tag="VV588_000382"
     CDS             complement(35462..35884)
                     /gene="fabZ"
                     /locus_tag="VV588_000382"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU7082781.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(35881..36366)
                     /locus_tag="VV588_000383"
     CDS             complement(35881..36366)
                     /locus_tag="VV588_000383"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU7082782.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(36369..37604)
                     /gene="fabF"
                     /locus_tag="VV588_000384"
     CDS             complement(36369..37604)
                     /gene="fabF"
                     /locus_tag="VV588_000384"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU7082783.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(37626..38357)
                     /gene="fabG"
                     /locus_tag="VV588_000385"
     CDS             complement(37626..38357)
                     /gene="fabG"
                     /locus_tag="VV588_000385"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU7082784.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(38391..39311)
                     /gene="fabD"
                     /locus_tag="VV588_000386"
     CDS             complement(38391..39311)
                     /gene="fabD"
                     /locus_tag="VV588_000386"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU7082785.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(39304..40278)
                     /gene="fabK"
                     /locus_tag="VV588_000387"
     CDS             complement(39304..40278)
                     /gene="fabK"
                     /locus_tag="VV588_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU7082786.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(40398..40622)
                     /locus_tag="VV588_000388"
     CDS             complement(40398..40622)
                     /locus_tag="VV588_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU7082787.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(40682..41656)
                     /locus_tag="VV588_000389"
     CDS             complement(40682..41656)
                     /locus_tag="VV588_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU7082788.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(41656..42090)
                     /locus_tag="VV588_000390"
     CDS             complement(41656..42090)
                     /locus_tag="VV588_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU7082789.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(42184..42969)
                     /locus_tag="VV588_000391"
     CDS             complement(42184..42969)
                     /locus_tag="VV588_000391"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU7082790.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            43339..44703
                     /locus_tag="VV588_000392"
     CDS             43339..44703
                     /locus_tag="VV588_000392"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU7082791.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYYAFFGE
                     SKED"
     gene            44706..45077
                     /locus_tag="VV588_000393"
     CDS             44706..45077
                     /locus_tag="VV588_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU7082792.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            45291..46565
                     /gene="serS"
                     /locus_tag="VV588_000394"
     CDS             45291..46565
                     /gene="serS"
                     /locus_tag="VV588_000394"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU7082793.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(46590..47489)
                     /locus_tag="VV588_000395"
     CDS             complement(46590..47489)
                     /locus_tag="VV588_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU7082794.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(47599..48147)
                     /locus_tag="VV588_000396"
     CDS             complement(47599..48147)
                     /locus_tag="VV588_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU7082795.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(48365..49681)
                     /locus_tag="VV588_000397"
     CDS             complement(48365..49681)
                     /locus_tag="VV588_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU7082796.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALTQS
                     AFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLMVL
                     LGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFNK"
     regulatory      complement(49772..49860)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(50024..52360)
                     /locus_tag="VV588_000398"
     CDS             complement(50024..52360)
                     /locus_tag="VV588_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU7082797.1"
                     /translation="MNKKILETLELDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKVKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(52464..53012)
                     /locus_tag="VV588_000399"
     CDS             complement(52464..53012)
                     /locus_tag="VV588_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU7082798.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(53009..53311)
                     /gene="zapA"
                     /locus_tag="VV588_000400"
     CDS             complement(53009..53311)
                     /gene="zapA"
                     /locus_tag="VV588_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU7082799.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            53398..54279
                     /locus_tag="VV588_000401"
     CDS             53398..54279
                     /locus_tag="VV588_000401"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU7082800.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            54283..54897
                     /gene="lepB"
                     /locus_tag="VV588_000402"
     CDS             54283..54897
                     /gene="lepB"
                     /locus_tag="VV588_000402"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU7082801.1"
                     /translation="MNSLKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKLLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            54977..55099
                     /locus_tag="VV588_000403"
     CDS             54977..55099
                     /locus_tag="VV588_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEU7082802.1"
                     /translation="MKIKEQTRKLAVGCLKQWFEVVDRTDEVSSKYCFEVADGS"
     gene            55176..57542
                     /locus_tag="VV588_000404"
     CDS             55176..57542
                     /locus_tag="VV588_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU7082803.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLTNQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(57590..58873)
                     /locus_tag="VV588_000405"
     CDS             complement(57590..58873)
                     /locus_tag="VV588_000405"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU7082804.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(59659..60795)
                     /locus_tag="VV588_000406"
     CDS             complement(59659..60795)
                     /locus_tag="VV588_000406"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU7082805.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(60857..61294)
                     /locus_tag="VV588_000407"
     CDS             complement(60857..61294)
                     /locus_tag="VV588_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7082806.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(61296..63251)
                     /locus_tag="VV588_000408"
     CDS             complement(61296..63251)
                     /locus_tag="VV588_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU7082807.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESI
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELIQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(63275..65044)
                     /locus_tag="VV588_000409"
     CDS             complement(63275..65044)
                     /locus_tag="VV588_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU7082808.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     VAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            65253..>65453
                     /locus_tag="VV588_000410"
     CDS             65253..>65453
                     /locus_tag="VV588_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU7082809.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMI"
BASE COUNT        19761 a        14403 c        12120 g        19169 t
ORIGIN      
        1 ttttcttatg tttaatataa aataaaccaa aggaggaaac aaatgattac aaaacaatca
       61 gcctttttac aaaatagagc cactatactg gagtttctat atcgaaatcc agcaacatcc
      121 cgtacagata ttgttaatga aacaggactt actccagcaa caacgactaa catcataaaa
      181 gagctaagcg aacagtccct catatacgaa actggtgatg aatttagcga gttttccgga
      241 tctggaagac gtagaaaaac tatttctatc acagataata ttccgtatgt tgttggaggt
      301 attgaaataa acgtcctagg tatctttctc agtctatgtg acttacaagg gaaaactctt
      361 ttcgagacag aaattttgaa tgaagattat cctatttcag aaatcaattc caccattacc
      421 aatatgataa aaacagctat agagtacgtc cctttggaaa caaaattact tggatttggc
      481 ttatcaatac ctggacatta taacaaagac tccggaagta tcattacaaa caaccccata
      541 tgggaatctt ttaatttatt aaatgtaatt aaaagattca attttccttt tattgtaaaa
      601 aataatatcg attgtatggc tataggacaa taccttttta atccacacaa tacccccgat
      661 aactttattt tcctgcacgc tggattaggt atttacactt cctttttcac aaaagaaaaa
      721 ataggagcct ctaaaaatcc ttatatcgga gaaattggac acaccattgt cgaattgaat
      781 gggcaatatt gtgaatgcgg aaaaaaaggt tgtttacaaa catatatttc ggatgcttgg
      841 ttaatcaaac acgcccaatt attatttaaa aattcccaac taactgtact aaaaagcctt
      901 gtaaagactg aaaaagacat tcatttagac acccttttaa cggcttataa tttaggcgac
      961 tccgctttac gtcaacaaat tgataaagga gtcaatttat tagccacttc tattgcaaat
     1021 ctcctcctca tcaatcctgc tgataaaatc tatatcaaca gtcaattgct taattatcaa
     1081 cctttcactc atgaagtcag ggataaaatc caagaccagc tccacttcgt tccctttact
     1141 cgtaatatag aaattgaaat tttaccttac aacaaacatc gtggaagtat aggagcttgt
     1201 gcattagcta tcgtcgcttt tttcatagaa catagcaatg tattacaaga tattatttca
     1261 ccttaatata ttagaaatct atagacctgt ttaaatcaac tataacctgt agtagatatc
     1321 tcgtatttag acaatatgaa aacaagacga cttccatata ggaaaccgcc ttctctctat
     1381 gttgagtgat ttatattaaa ataacttttc ttctagctgc attttattat tataaaaaca
     1441 ttcatcataa ccctgaactt aaataacgat ttttattcaa gatacatact cctagaataa
     1501 actttatatg aaattctcat ttttgttttt acaattctcc ttagttaaat cttgtttaat
     1561 atatgtttta catatagtat ttagcgccac atagtactga actctctcca aaaacggtta
     1621 ttcctctttg aatagggcgt tatcacaaga aaagcatctc cacgtttcaa cttcatatgg
     1681 ctcaaaaaca atcaattgat gctaaaacct gtacctagat gtttcggttc ataaaaccat
     1741 gaaactgtaa aagtggatga aattgatagc gatagtcaaa tcaagaggca tcataactct
     1801 aaaaagtcac aatatataag ttcatcctcg gaaaaatatc attctaattg ttgaaatgcc
     1861 tacatgaaaa gaaacgtcaa atactcatga aacaacgaat acaggtatca aaactatgac
     1921 aaaacaagtc cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt
     1981 gtataataaa gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata
     2041 tattactgat agcatttcta caaatacaat tgaagagact ggatagactt taaacgaaat
     2101 atgtcagtgt tttggcattc ctagccttca tatcatttaa agaattctat agacaaaatt
     2161 tttcccaata cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca
     2221 ggataagata caagaggatt aatccataga tcagttctat accaatctaa gacaaataag
     2281 ctaaaaaaac gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta
     2341 ataaacaata ctagtgtaac tatccttcca gtcagaagct tgtcaaatca caccgaaaat
     2401 tcttctaaaa tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta
     2461 tcatacagaa ttgacttcct aaattatata ctttagtaag gttttcgtat aagaaaaaag
     2521 attcatttta catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg
     2581 atttaaagca acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa
     2641 ctacattttc gaatataaac tacaataata taaactaaat tttataggag gaagacaatg
     2701 gattggtacg attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg
     2761 tttcgctatt tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta
     2821 gaaaagttgc tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc
     2881 tttcaagagc atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta
     2941 accaatgttc aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca
     3001 agccctaaat aaggaattaa ttcaggaaaa tctgacttta acaattatct gtgtcgatgg
     3061 ttatgtctta gaatatcatg gtttacatgc cacacaagat gttgatgctt tttatgacca
     3121 aaatcagaaa atcaatgaaa ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca
     3181 cgaagagtta tggctcaaca atcatgttgc aaagcaaata tgaacaaaca acctccctta
     3241 agtttatgcg aatccttgta ctcatttgag aatctgaccg ttttagtagt ccctattgag
     3301 tatgtgttag gaatgaagat gatgagtatc agagagcagg atttgcaaga tattggtgca
     3361 attattaaat acaaaaactt tcattcacca ttcgatacct ttaaatattt aaaagacatg
     3421 ggatttgata ctattgacct ctctgttcta ttagaaagtt ttagttatgc ttatggtatg
     3481 gattggttag aaaaattttt taaagaaaat caagataaac ttcgcgaatt ttattaacag
     3541 tatcaaacaa gatgattgtc aattagccag tcgtcttgtt ttttatgatg aaatgaaata
     3601 aaatctgaac aaatcgctta gagaattcca gtcaatttct agcgctgttt gagacgtttc
     3661 agtggactat agtaaaatga aataagaata ggacaaatcg atcaggacag tcaaatcgat
     3721 ttctaagaat gttttagaaa taaaggtgta ctattctagt ttcaatctat tatatttcag
     3781 attcggtcca ctattccttc ccaaaaacat tgcatattgc gccgaaggaa ttgctcatac
     3841 tatcccaagc acaaaaccct cagtcgtttg accgagggtt cctttttatt attcaagaac
     3901 ttgattagct caatgcatcc aaggcgtcat ccattgaaag aacttcgtgg aagacacgtt
     3961 gtgtcaattc agttttttgt tctggagtga ggtatttagt gtttacacag tatccagaga
     4021 tacgtacgat aacgtcttcg cctgacatga ttttttcgta aacatcgttc aagtccataa
     4081 cgttcaagtt aacgtgttgt ccaccgtttt cgaagtaacc atcaaggatt gttaccaagt
     4141 tatcaacttg ttcatcacga gtcttaccaa gagcgcgagg tgatacttgt gtagtcaatg
     4201 agataccgtc agctgcataa ctaaagtcaa ggctagaaag tgagttcaag ttttgcaacc
     4261 aaccaccttt agctttgtta gatgggttag cacctggtga gaagaattca agtttagaca
     4321 agttcacaga accatcttcg ttgaggtata cacctttgtg aactggtgag ttaccagttt
     4381 gtttagagta agcaacgtta gatgtgattg tcaaaagtga tactgtagct tctgcgtctt
     4441 tgtatagttt gtggctacgt agacgagttg tgtaagcttc gatcaaccat tctgccaatt
     4501 cgtttgaacg tgggtcatct tcaccccagc gtgggtagtc accgattgtt tcgtaatcgt
     4561 agatgtagcc atcttcgtca cggattggtt taactgtagc gtatttgata gctgacaatg
     4621 tatcaacagt gttagcaaat ccacagatac cgaatcccat gttggcacgt tgtttagttg
     4681 gcaagaaggc catttgaaca gcttcgtagt tgtacctatc agtcatgtag tggatgatgt
     4741 tcaaggcatc tacgtaagtg tcagtcaacc agtcaagaga tttttcaaag ttcgctttaa
     4801 ctgattcgaa ttcaagaact tcgtcacgga ttggttcgat atcaaatact ttgtagtctt
     4861 tgtgaacatc gtcgtaacca ccattcaaac cagtaagaag ggctttaaga acgtttacac
     4921 gagcaccgaa gtactggatg ttgtggcgtt gttcttcatt ttctggatca agtggagaca
     4981 cacagcatga gatacagctc atttcaccat atccgtcttt agccattgtt gttacacctt
     5041 cgtattggat agaagagtgt ttgtggctca tgtgcataca gtagcgacgg aagttgtatg
     5101 gcaatttgtc agtccaaaga actgtcaagt ttggttctgg tgagttaccg atgttgtcaa
     5161 gagtgttcaa gaaacggtag tccatcttag taacacggtg acgaccgtcg ttacccatac
     5221 cagccataga agttgtgata aaggttgggt cacctgagta caattggtca taagctttgg
     5281 tacgagcaaa tttaactgta cgaagtttca taacgaaatc atcaacgaat tcttggattt
     5341 ctgattcagt aaatgtacca cgagcaaggt cacgttctgc aaagatgtcc aatacgattg
     5401 gtacacgacc tagagatgta gcagcaccgt taatcacacg gcagacagcc atgaaagcaa
     5461 tgttaaccca ttggattgct tctttcacgt tcatcgctgg tttgcgaaca tcaaccccgt
     5521 aaaggtcacc caggcgaaca acttgttgca atgcttggta ttgaaggttt acttcttcac
     5581 gaagacggat tgtttcttca tcgatttctt tgattgcatt ccagtcattt actttttctt
     5641 gcatcaagta gtctgcaccg taaagagcaa gacgtgcgta aacaccgatg atacgtccgc
     5701 gtgagtatgc atctggaaga ccagttacag tgtgtgcgtg acgagcgcga cgaatatttg
     5761 aagtgtaggc acggaaaata ccgtcgttaa ctgttgttac atatttagtg aagatttcgt
     5821 gaacagctgg gtctggttcg tatccatttt ctttcaaagt agtttcagcc atacggatac
     5881 caccttttgg catgaagttc aatttgaaga gttcatcgtt ttggataccg aagataactt
     5941 cattttcttt gtcgataaat ccagcaggga tatcagcgat agatgttgga cgagtgtcca
     6001 ttgggaaacg agtttcttcg tagtgtgctt tagtttcttc tacaattttc ttgatgtgaa
     6061 gtgaacgctc tgttggtcct gcaaggaagc tttcgtctcc atcataaggt gtgtagttag
     6121 cttgtacaaa tcgtgataca cttgcttttt ctttccaatc tacgcctttg aagccttccc
     6181 aagctttgtc aaaaatatct tgtgcttcaa caactgtctt aacaaccata ttaatgtcct
     6241 cttttttcta gtaacagtca tctgttacat tcataagaca agtataccat atagtaaccg
     6301 atttcaacaa gtgaaaattc cctattttta cactttcttt tctaaaacag tctatatttt
     6361 atttcaaact gtattatatt tttgaaaaaa taaagtcctt ttttcttttt ttcagaaaaa
     6421 agggtataat aaaagaaaat aagcagtaac actcaatgga aatcgaaaag caaactagga
     6481 agctagccgc agattgctca aaacactgtt ttgaggttgc agatagagct gacgtggttt
     6541 gaagagattt tcgaagagta taaaaaggtg ctaggcatgt tgatttttcc tttgttaaat
     6601 gatttgtcaa gaaaaatcat ccatattgac atggatgcct tttttgctgc agtggaaatc
     6661 agggataatc ctaaactcag aggaaaacct gtcattattg gaagcgaccc tcggcaaaca
     6721 ggtggacggg gagtcgtttc tacctgtagt tatgaggcaa gagcttttgg tgtccattct
     6781 gccatgagtt ccaaggaagc ttatgaacgt tgtccccagg ctgtctttat ctcagggaat
     6841 tatgagaaat acaagtctgt gggactccag attcgagcta tttttaagcg ctatacagat
     6901 ttgattgaac ccatgagcat tgacgaagcc tatttggatg tgacagaaaa taaactcggt
     6961 atcaagtcag cggtcaaaat tgctcgcctc attcaaaaag atatctggca agaactccat
     7021 ctaactgctt ctgccggtat ttcctataac aagttcttag ctaaaatggc gagtgattat
     7081 caaaaacctc atggtttgac agtgattcta cctgaacagg ctgaggattt tctcaaacaa
     7141 atggatattt ccaaatttca tggagtagga aaaaagacag tagaacgtct tcatcaaatg
     7201 ggcgttttta ctggtgctga tttacttgaa gttcctgagg tgaccctaat agaccgtttt
     7261 ggtagactag gctatgatct gtatcgaaag gctcgtggca ttcacaactc tccagtcaaa
     7321 tccaatcgca tccgtaaatc aatcggcaag gagaaaacct acgggaagat tctctgtgct
     7381 gaggaagata tcaaaaaaga gctgactctt ctatcagaaa aagtcgctct caatctacat
     7441 caacaagaaa aagctggaaa aattgtcatt ttgaaaatcc gctacgagga cttttcaact
     7501 cttaccaaac gaaaaagtat tgctcaaaaa acacaagatg ctagtcagat aagccaaata
     7561 gccctgcaac tctatgaaga attaagtgag aaagaaagag gtgtccgcct attggggatt
     7621 accatgactg gattttaaag ctcaatgaaa atcaaagagc aaactaggag gctagccgca
     7681 ggctgctcaa aacactgttt tgaggttgca gataaagctg acgcggtttg aagagatttt
     7741 ctaagagtat aaaaccttga agagttgccc cttcaaggtt tttcttatac aaataaacgg
     7801 acaaaactgt aaagtagcaa aacactacca agcacgatac ggtatttacc aaaaagggtg
     7861 aagtcgtgtt ttttcacata gctggtcaag aagcgaatag ccaccatgct gaccgcaaaa
     7921 gctactccca tcgcgaccaa gagcaaaaac aattgcccaa agctcaagag ttctccggct
     7981 ttcacaaatt tgaaaatctt taaggcacta gctccaaaca taacaggaat cccaagatag
     8041 aaggtaaatt ctgtcacaac tgaacgactg gttccattta acaaaccacc gacaatcgtt
     8101 gcacctgaac ggctagtccc tggtaaaaga gcaagaactt ggaagagtcc gatatagaaa
     8161 gcggtcgtat aaggaagctt gtccaactct gttacacttg gctcgatagc acgcgcttta
     8221 ttgcgctttt ccaaatagat gaaggcaacc ccgtagataa tcaacatgag agcaactgaa
     8281 accatgttat ggaagtgggt atcaaaccaa tcatcaaatt taaagacacc aagtaaaggt
     8341 aaagtagcaa tcaagacctt caaccatagt ctccaagtct tacgaacttc ctgtttgtcc
     8401 ttagtcggtt taaaaggatt gagcttgtta aaataaatca ccataactgc taaaatagca
     8461 ccaagctgaa tcacgacatt aaacatggac ataaaggctt cattttgatt ttggtattgg
     8521 atgaattcct ctgctaaaat caagtgacct gtactggaaa tcggcaacca ttccgtaatt
     8581 ccttcaacaa tcccgaagaa gatagatttt aaaatttcaa taagatacat agattactcc
     8641 ctatattata attagcgcag ttagctactg ccaaagccca agtggtatac ttggaataag
     8701 ccactgtgga ttagttcatt tcctccaatc gcttgacgat ttccgaaagg atctaaccac
     8761 agcttttgtt tcaattggta atgagtttga taacgcatag acgttttatc tcgtctaagg
     8821 taacaaggca aaaagttcgt ggataaccaa gtagacttga aatactatat ctggaggtac
     8881 tcccatgctt tatgtgggca ttgatatcgc taaaaataaa cacgatgtta cagccttgaa
     8941 tgttccagga aaaactgttc ttaaaccact cactttttca aataataaag ctggttttga
     9001 actcttagat ctgtctcttc gacagctcaa ccaagactgt ctcatcgctc ttaaacttct
     9061 ttctgacccc aatcgtgaac aatttcaaca cgataatcgg caagtagacc taaaaatact
     9121 ggctagacat attcatcgtc tcaagaaaaa acagtctgat tggaaagtac aatacactcg
     9181 ttgtcttgat atcatctttc ctgagttgga taaaatcgtt ggaaagcatt cagaatatac
     9241 ctaccaactc ttgacgcgct accctaatcc tcagaaaagg attgaggcag gatttgataa
     9301 gctgatagaa attaagcgat tgaccgcttc taaaattcag gatatcctct cagtcgcacc
     9361 tcgttctatc ggaacaacat ctcctgctcg tgaattcgaa atcatcgaaa tcatcaaaca
     9421 ttacaagagg ctcattgaca aggcggaaac atgtgtcaat gacttgatgg ctgagttcaa
     9481 ctcagtcatc acgacggtta ctgggattgg gggtcgttta ggggcggtca ttttagccga
     9541 gattcgaaat attcatgcct ttgataatcc tgctcaatta caagctttcg ctggactgga
     9601 ttcttctatt tatcagtcag gtcagattga tttagctgga agaatgatca aacggggttc
     9661 ccctcatctg cggtgggcac tcatacaagc tgccaaagca tgcgctcgct tttcacctgc
     9721 ttttaaggcc tatcttaaga ctaagttaga acaaggaaaa cattacaatg tagccatcat
     9781 ccaccttgca aaaaaactta tccgaaccct gttttatatc ctaaaaaaga gctgccattt
     9841 gacgaacaaa aagtgatgta atttctgaaa ttaacacagg attacctttg aaaaaatgga
     9901 ctttttcaag ggctttttgc cgtgctctaa aatcatcgcc aaatcatcaa attgaaataa
     9961 gaaatagttt agataaaact attgactttt cttatagttt gtctttcttc tatcttccat
    10021 tatatcatac tttttcagtc tatggtagct ctctttaaaa ggctccgata ctgccgccac
    10081 ctccgcctcc agagaagcca ccgccagaac ttccacttcc agaagatacg gagtaggtac
    10141 ttgctgtatt tgcgacacta gcataatggc tcatttgcgc gcttgaatga taaaacatac
    10201 tgtgccagcc ataagctaca tagagattga tatctggatt ttcaacttga atctgatgaa
    10261 ccttcatcaa atgactaacc ttgtccgcat agccaaataa ggttgcatag accaagagac
    10321 gattccaaac aacaatactt tccaattcag ccttatccag tcgtgcaatc tcacgtaaca
    10381 tattttcaaa actggtccag agatagtaga cctcagctcc cgcttcattt agaacaccat
    10441 cacgattatc tagtcgaagc ttccaataat agaaaacaga caaaactaac cctagaaaac
    10501 caagtattgg caaagggagg taaagatagc catgaacgtc taaactgtac aagaacaaac
    10561 caaatccgat aaataggggc aagatagtca agacacccat acccacttgc aaagtctttt
    10621 ccaaaccagt taaaggacga tagtaatctg ggagccccca gaaggaaact cgttttctca
    10681 ctccttcttg catctggttc aatacctctt caaaagaaga tttgagttga agccctcttg
    10741 cttgaatccg tttttcatca gaaactttgg ctctacgata aagactatca gataccttgt
    10801 aatccgcaaa caaattggaa agagtggctt cttttttgcc tgaaaaggct agatttagac
    10861 agtctctctc aaatcttgac aaaccatctt ctttcaccaa tctcaagcca actgcatctc
    10921 cttctgaaat aatagagaca ttcccacggt ctatcacatc tagcaaggta gcttgaataa
    10981 gttgatcaaa ggtgaatttt ccagctccct tgaccaaggg actcacttcc tccaaggagg
    11041 tcgagtagac tgcttctgat aaaaccatag gctctaattc cattggtggt tcatagagac
    11101 gatgattttt ggcatatttg actgaaggag tggtctttct tctataaata aaatagaagc
    11161 agacactcaa taacaaggag atggaaagga tcgaagggag gacccaagta acgagttgtt
    11221 tactctgatc tttttctcta acaatcgagt cttctatctt attaaactct tctaaacgat
    11281 tccctttcaa gccctgatcc ctagcgctag caaaatcggt ccgagaccaa taggcatgca
    11341 actcaactcc acgcttagcc ggaagattgt ctaaacggat agtataatca aggttactct
    11401 tttcaatcgt tccctctcta aaaagtttcc ctgtatggaa aaagagtttt tcagccccct
    11461 tgtctcccct tacatgaaat tcaaactttt caatagactc tgaactatct gtcagaggtt
    11521 gccaatttaa ttcagcgata tcatcataaa ggaaaagtaa attttttaag ttccagacga
    11581 ggtcaacttc aactatgtcg ccctcctgac ctggattata gactctcaca gtataaccat
    11641 ccgcttcttc tgttacttcg ctagtcacat ctgctagttc tgcaccgttt ttcgcagcct
    11701 gaacctttgg atgagggtca atgtcaaacc cgctaggcat cttaccagca cgtccaagtc
    11761 ccacgatttg gcccttaaag tcctcctcaa actggtaaac tatcttctgt ctaaactctg
    11821 ccgtattatc tgcatgaata tacaaatccc cttgataaga gtttatcttg aaatcaatgg
    11881 caaaaacaga gagtggaaga aggcaaaaca agcctaacac cagtaagaaa aaagtttttt
    11941 tcatcaacta agcccccttt ttatctttct tatcattata gcattttttc gtaagtaaag
    12001 gcttacttat gttgaaaaat tacgcatttt tcgataaaat aggagacagt tattttttaa
    12061 tagatcagaa taggagaaat catgagaaaa atatacttat ctattttcac aagtctcttg
    12121 ctgatgctag gacttgtcaa tgttgctcaa gccgatgaat atttacgcat cgggatggaa
    12181 gcagcatatg ctccctttaa ctggacccag gatgatgata gcaacggagc tgtcaaaatc
    12241 gatgggacca atcagtatgc caacggatac gatgttcaaa tcgccaagaa aatcgctaag
    12301 gacttaggta aagaaccttt ggttgttaaa accaagtggg aaggtctagt ccctgccctt
    12361 acttctggta agattgacat gattatcgca ggtatgagtc caactgcaga acgcaaacaa
    12421 gaaattgcct tttcgagcag ttactacact agcgaaccag ttttgcttgt caaaaaagat
    12481 tctgcctacg caagtgctaa atctttggat gactttaacg gtgcaaaaat cacttctcaa
    12541 caaggggtct acctctacga cttgattgca caaatcccag gtgctaaaaa agaaacagcc
    12601 atgggagact tcgctcaaat gcgacaagct cttgaggctg gtgtcattga tgcttatgtt
    12661 tctgaacgtc cagaagcact gactgctgaa gctgcgaact ctaagttcaa gatgattcaa
    12721 gtagaacctg gtttcaaaac tggggaagaa gatacagcta tcgctatcgg gcttcgtaaa
    12781 aatgacaatc gtattagcca aatcaatgcc agcattgaaa ccatttcaaa ggacgaccaa
    12841 gttgccctga tggatcgtat gatcaaggaa caacctgccg aagctacaac aactgaagag
    12901 actagcagta gtttctttag ccaagtcgct aaaattcttt ctgaaaactg gcaacaactc
    12961 ttgcgtggtg ctggtatcac tcttttaatc tctatcgtcg gaaccatcat aggtctcatt
    13021 attggacttg ccattggtgt cttccgtact gctcctctct ctgaaaacaa agccatttat
    13081 ggccttcaaa aactagtcgg ctgggttctc aatgtctaca ttgaaatttt ccgtggtacg
    13141 ccaatgattg ttcaatcgat ggttatctac tatggaactg cccaagcttt cgggatcaac
    13201 cttgaccgta cactggctgc tatcttcatc gtttcaatca ataccggtgc ctacatgact
    13261 gaaatcgtcc gtggtggtat cctagcagtt gacaagggac aatttgaagc tgcgactgct
    13321 cttggtatga cccataacca gaccatgcgt aagattgtcc tacctcaggt agtccgtaac
    13381 atcctacctg caactggtaa tgaatttgtc atcaatatca aagatacatc tgtattgaac
    13441 gttatctctg ttgtcgaact ttatttctca ggaaataccg tggcaacaca aacctatcaa
    13501 tacttccaga catttacaat catcgccgtg atttactttg tcctcacctt caccgtaaca
    13561 cgtatcctac gctttatcga gcgcagaatg gacatggata cctacactac aggtgctaac
    13621 caaatgcaaa cggaggattt gaaataatga cacaagcaat ccttgaaatt aaacacctca
    13681 aaaaatccta tggacaaaac gaagtgctaa aagacatttc tctcactgtc cacaagggag
    13741 aagttatttc tatcatcgga agctctggaa gtgggaaatc aaccttccta cgctccatta
    13801 acctacttga aacgccaact gatggacaaa tcctttatca tggacaaaac gtcctcgaaa
    13861 aaggctatga cctcacgcaa taccgtgaaa agttagggat ggttttccaa tcctttaacc
    13921 tctttgaaaa tctcaacgtt cttgaaaaca caatcgtcgc tcagacaact gtccttaaac
    13981 gcgaacgcac agaagctgaa gaaattgcca aagaaaacct ggaaaaggtc ggcatgggag
    14041 aacgctactg gcaagcgaga cccaaacaac tctcaggtgg tcaaaaacaa cgtgtggcca
    14101 tcgctcgtgc cctttcaatg aatcctgacg ccattctctt tgatgaacca acatcagctc
    14161 tcgatccaga aatggttgga gaggtcctca aaatcatgca agatctggct caggaaggct
    14221 tgaccatgat tgtcgtaacc catgaaatgg aatttgcccg tgatgtctct caccgtgtta
    14281 tctttatgga taagggtgtg attgctgaag aaggtaaacc agaagacctc ttcactaatc
    14341 ctaaagaaga ccgtacaaaa gaatttcttc aacgttatct catactcaat gaaaatcaaa
    14401 gagcaaacta ggcagctagc cgcaggttgc tcaaaacact gttttgaggt tgcagataga
    14461 gctgacgtgg tttgaagaga ttttcgaaga gtatcaaata aaaagaaaag gctgcatcaa
    14521 ccgtgcagtc tttttgctgt cctcaaaatg aaaaggcaga ttctctatct ctactacttg
    14581 aaggtcaaga atccaccgtt atccaaagat taatcttcaa atttttcatg atttttttca
    14641 tagaaatcaa ttaagcctag ggctgtttca aatgaaatat tttttacttt tgcacgaccc
    14701 tgcgccagag caatgataga catttcacgc gcattcgttt ctttagagat acggtagcct
    14761 gtgattttct tatcacgaac ccagccaaca actgattcta ctttttcaaa gtttgactta
    14821 gccatgtttt tctcctattt tcttctttat aatatttaat tgtatacgtt tttactactt
    14881 ttgtcaataa aaaaaacata tattcaacga aaataattag ttcagaattt tcttacttcc
    14941 tttttaaatc cgataatata taggttttgc tagcctctac accataaata tttgctaata
    15001 aaaatactgt attattaccc tcttaaggtg cgaaattatt caagttctta aaaaatgctt
    15061 ctctatttcc gtaagatagc ttatttcttc gatttaagaa ctgaagatga tagttctaac
    15121 ctttagaaat ccaagccttc tctagctcaa aaactcctat ctttcttcct caataaatca
    15181 tctgagagat aggtattcct tatatccttc aaattcatca ctcctttgga tattgaggtg
    15241 ctagcctaga agcagacacc cgattatcta aaccatcctt aatagagatg acaagacaga
    15301 taagctcagt taattactta tatatctttt taatatggta tatttgtcaa caaaaagaaa
    15361 tcaaatcata ccttatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaaat
    15421 tgctcaaaac actgttttga ggtttcagat agagctaacg tggtttgaag agattttcga
    15481 agagtattaa agacagtatg actatgcttg tcaatagata ggaaatcaaa atgaaggatg
    15541 gaaatctgag ccaaacatca taagtgctat aatgaacaga agtaagaatt gcacgataag
    15601 ttttctaaaa ccataggaat cgtccccttt cttcatcttc attatagcac atatacatca
    15661 gttgtacaaa taatatgata tttttttatt agtcctcaga caagcatatt ataaagcgtt
    15721 tcattaccat ttaagttaat ataagctgga tcaaaacctt ccattctacg gatcaaacct
    15781 gcataatcat gcttatctgc caaagcgatc ccaatcaata ctgggcctgt tcccttgcta
    15841 gctcgtttga tatactcaaa acgtgtgata tcatcatttg gccccaggat atcatttaca
    15901 aactcacgca aagctcctgg acgctgtggg aaattgacca caaagtaatg tttgatacca
    15961 tcataaatca aggcacgctc ttccatttct ggcatacggt tgatatcatt atttcctcca
    16021 gaaatgatac aacaaatggt tttcccctta atatattcag ctaaaacctc taaagaggcg
    16081 atactagccg ctccagcagg ttctgcgact atcccttgct tagagtaaag gtcaatcaag
    16141 gtttcagaaa tcaatccctc atcgacacct accaaagttt gaatatgttg acgagttgct
    16201 tcataggtca actgacctac cttttgcaca gcaatcccat ccgcaaattt atcaatttcc
    16261 ttgagtttga ctggacctcc agcctcaaag gcagctttca tggaacgcgc tccattcgcc
    16321 tctactccga taacctcaat ctctggactt gtttccttga tataggtaga aaccccggca
    16381 atgagaccgc caccaccaac aggaaccaag acagcatcaa aatcaatcga ttcttttcga
    16441 gcttcttcta aaatctcata agcaactgtt ccttgacctg cttgaacatg agcatcatca
    16501 aaaggatcaa taaaggtacg attttcagag actgtaaatt cttgagctgc tttggctgag
    16561 gcatcaaagg tatctccaac tagtttaata gttacaaaat ccccaccaaa aaagcgaacc
    16621 tgaccaatct tttgttgtgg cgtagtaata ggcataaaga tagtagcagg aattttcatt
    16681 tcattacaag tataggctac tccctgcgca tgatttcccg cagaagcgca gactacccca
    16741 cgttcacgtt cttccttgct gagctgggaa atggcataat aggcaccacg aattttaaag
    16801 gagcgaacac gctgggcatt ttcttttttc aaataaatct tagcaccata cttctccgat
    16861 aaataatgat cgtaatccag tggagtattc acaaccacac cgttcaagac cttgtgagcc
    16921 ttgattatat cttttgaact taacatataa aacctctttt tctataaaaa acagtcacta
    16981 atgactgttt tttagttatt catctccgaa aacttcagta acactttcat ggtatttatg
    17041 agccatacga atcgaaaact ctttaggaag ttcataacga tttgtggaaa tccaatcata
    17101 taaccattct accaaacttt cttcactatc attacgatgg aagataaaat agtttaaaat
    17161 ttctttatat tctacatcat tcaaatccaa cgtgtctaca aattgactac gaggaacaaa
    17221 attagaatct aattttctta gttgatctgt caattctccc aattgtaaat ccaactgaaa
    17281 aaatagtttt tgcagttgcc tatcagtttc atcacatcct gtcttgatag aaaacaaatt
    17341 ggtaatattc atatgatttc aacccctaaa taagtacatc taatatccca cgaatagctg
    17401 aagctaaagt tttcgcagtc cagtcattta aacccgattc tttcaatcca gatgcaataa
    17461 tttgctctat ttgatataaa ccgccatcta tcgtctcatt tattctgcga agaggacctt
    17521 caatatagga taaagcttct ccgaatctaa cagctgattt aggtcctaat gatttaccaa
    17581 ctatatttgt taatgttttt tatttctcaa aatccatttc gctatataac gagcagattt
    17641 agtcgcacca gctctctcaa acggagaatg aatttcaaga ccttcttctc tagctatttg
    17701 tgccaatttg aagaattgtt caaaggtcat atgcaaccta ccatcttcaa aattagcatc
    17761 atcataaatg ttaattacag cattttcatc atacgaccaa tctgctttat tttggtctgc
    17821 tagcactatt accgacggtg taattacatt atacaactag aaccaataat aacgatgcaa
    17881 tttttctcat aatctttttc ataaaatcat ctccagcgct atatatttct aattagttat
    17941 agattttgaa tgcatcatcg tcgtttttac caacaaatgg cattgcttta cgcaattctg
    18001 caccaacttt ttcaatttca aggttagctg cttgttcacg gtaagcagtc aattttggac
    18061 gtccagcttt atagtcattt acaaagtcat ttgcaaattt accattttgg atgtctgcca
    18121 agacagcctt catattttct ttaacttgtt cagtgattac acgtgaacct gatacatagt
    18181 caccgtattc agcagtgttt gaaatagatt gacgcatttt cttgaatcca ccttcgtaga
    18241 tcaagtcaac gatcaatttc atttcgtgaa gaacttcaaa gtaagccaat tctggagcgt
    18301 aacctgcttc tgtcaagact tcgaaacctg cttcgataag ggcagtcaaa ccaccacaaa
    18361 gtacagcttg ttcaccaaac aaatcttctt cagtttcttc tttgtaagtt gtttcaagaa
    18421 gacctacacg agccgctcca acacctttac accagtccat agcaatgttt ttagcatttc
    18481 ctgttgcatc ttggtatact gcataaagag ctggaacacc aaatccttct tcgtaagtac
    18541 gacgtaccaa gtgtcccggt cctttaggag cacacatgaa gacatctaca tccgcaggaa
    18601 ctttgataaa ttcaaagtgg atgttgaaac catgggcaaa tccaactgcg tttccagctt
    18661 ccaagtttgg agcgatttct gcttcgtaca attcttgttg aatttcgtct ggcgccaaga
    18721 tcatgataac atcagccaac ttagtagctt ctactactgt gtaagtatca aatccatctt
    18781 cttttgcttt atcaaaagat ttacctggac gtacaccgat aataacgtca cgacctgaat
    18841 cacgcaagtt ttgagcatgc gcatgtcctt gtgaaccata accgataacg gcgatttttt
    18901 taccgtcaag tgctgctact ttaacatctt tttcatattc catttgaact gtcatagctt
    18961 ttctctcttt tctattattt attgcctttt aggctggttt aataaattta agttggattt
    19021 ttaatcgcgg gtaaatccag ttgcacccgt tcgagcaata ttgcgaatac cgtatgggcg
    19081 aatgactcgc aatagggctt cgctcttttc tgcatttccc gtcatctgaa tggtaatcga
    19141 gcttggcgct acgtctacca ctgttgcacg gaaaggttga ataatcgcta aaatctcagc
    19201 tctcttctca gctggcgctg acatcttaac caaaatcacc tcgcgctcca aatgaggctt
    19261 gtctgtaata tctcgaatgc gaatcacatc aatctgacga ttgagctgtt tgatgatttg
    19321 ctccacttca tcatgagaag caacatcaat aataatagtg atacgcgata cattcggatc
    19381 ttctgttgct ccaacagaga tgctttcaat attaacctga cgacgagata ggacacctgt
    19441 aaagcgattg aggactcctg aacgattttg tagttttgct gttaacattc tacgcatgga
    19501 actgcacccc caacatctca tgattactct taccagccgg taccattggt aacacctgtt
    19561 ccttacgaga aatatctacc tcaattagca taggaacatc ctcagtgatg acttcaaggt
    19621 cttgagccaa ggtctcagga ttgtcaaact tatagttttt aataccataa gcctgcgcca
    19681 tcaattggaa atcaggaagg gtatcaaaga ccgactctga tgttctgcct tcatagaagg
    19741 attcctgcca ctggcgaacc attccaagtg aatgattgtt cagcataacc accttgattg
    19801 gcaccttgta aatattcaaa atagccaact cctggttggt catttggaaa ccaccatccc
    19861 caacaaacaa gactacttcc ttatctgggt tagcaatttt agcaccgatt gctgctggaa
    19921 ttccaaagcc cattgttccc aaaccacctg aagtcactaa ctgacgctca ttttggtagg
    19981 gataatactg agctgtccac atttggtgtt gaccaacgtc tgttaccaca atggcatctc
    20041 cattcgtcaa ttcaccaatt cgttcaataa ctgcttgcgg ttgaaccaca cgctctttct
    20101 tgtcataaga acgaacacga ttcttgtctt tagtgacttt ctcaatccac ttttcagtat
    20161 tgttgtgaac tgttggttct gctagcaaca tttgcaaggc cttcttagca tctccaacta
    20221 caggaatgtc tgcactgata atcttgccaa tctcagctgg gtcaatatca atgtgggcaa
    20281 ccttagcatt cttagcgaaa gtcttaggat tccccgtcaa acggtcatcg aaacgagaac
    20341 caatactaat cataaagtcc gcttccgtca tggcaatatt tgctgcgaat gacccgtgca
    20401 tgcctcccat tccaagaaag agtgggtgac tcgttgcaat cgttccttgt cccaaaagac
    20461 tggttaccac tggaatttga tagcgttctg caaattcatt tagttccgta gcagcctcag
    20521 cataactaat tccaccacca gctaacaaga ctggcttttt agccttggac aattgcttca
    20581 agattttctt gatttgcata tcattcggct caagagtcgg ctgataactt ggtaaattca
    20641 cttctggtga ataaatgaag tctgtttcta aagcagatat gtcttttggt aggtcaatta
    20701 caactggccc tggacggcct gtagttgcga tatggacagc ttccgtaatg atacgcggaa
    20761 tatcagctgt ctcacgaact tggtaattgt acttagtgat tggcatggta attcctacga
    20821 tgtctgcctc ctgaaaggca tccttcccaa tccctgctcg cgccacctga cctgtaaaga
    20881 ccaaaagggg aacgctatcg ctcatagcat ccgcaatccc tgtaatggca tttgttgctc
    20941 ctggtccact agtgacgacg gcaacaccca actttccagt tgatttggca taaccttcag
    21001 cttcatgcaa acaaccttgc tcatggcgcc ctagaatgtg gcgaatgcct ttaaaattat
    21061 atatcgcatc ataaaaaggc aaaaccgcac caccaggata accaaagatg gtatcaactc
    21121 ctaaatcacg aagtgtttcc aaaactaggt ccgaccccgt cttaggagat tctaaactga
    21181 ttttctccat tgttcccctt tctttcctct taaaaataac ttgttactat cataccattt
    21241 tttcaaaatt tttcaagata aaagaagaaa ttttctgaat tttctatttt aacgtttatt
    21301 tatgaatgtt atttttgttt ttattaaaaa gataccgatt tcatttacta aaaaagaaaa
    21361 aagaactgat ttctcagtcc ttcattaatc ttattccaca ctaaataggt atgggtaaac
    21421 aggttgttga ccttggtgaa tctcgacttc aacgtcttcg aattcttcta cgatttcttg
    21481 agcgatttca ttggcaagtt cttcgcttcc gtcttcaccg acatagaagg ttacgatttc
    21541 actatcttca tccaacatat gtttcaaggt ttcagtcaat gtttggtgca tatcagggtt
    21601 tgacacaaga atttttccat ccaccatacc tagattatcg ttttcatgga tttctaagcc
    21661 atcgatcgtt gtatcacgca cggctgttgt gacgcttccg ctaacgacat cgctaagagc
    21721 agctgtcata cgctcttggt tttcttcaat ggacttgctt ggatcaaagg caagaagact
    21781 tgtcatacct tgaggaagag tgcgagcctc taccactact gctggttgct ccaaaacttc
    21841 tgccgcagat tgagctgcca tgaagatgtt cttgttgttt ggcaagaaga tgatgttacg
    21901 ggcattgacc tgttcaacag ccttgataaa gtcttctgtt gaagggttca tggtttgacc
    21961 gccttcgata acataatcca cgccttgaga acagaagata tctgctagac ctttaccagc
    22021 caccacagca atcaaagcat actctttttc ttcagccgac ttgataactt gagtagcttc
    22081 tttctcaacc tgtgcttcgt gttggttacg catattgtca acttttacct tgaccaagct
    22141 accatatttg agaccttctt gcataacaag tcctggatct tctgtatgaa catggacttt
    22201 gacaatttca tcatcgttaa caacgaggag agaatcccca agctcatcca agtagttacg
    22261 gaattcatcg tagtcaaaat ctttagcata ggttggacct tgcttaagag ctaccatgat
    22321 ttcagtacag taaccaaacg tgatgtcctc agtcgctacg tgaccagcta cagacttatg
    22381 atgctctaca ttgatcatct cactcatgtt ggcaggagtc gctacaaagt cctcagatgc
    22441 aatatattcg ccagtaaggg ctgaaaggaa accttcgtag atgaagacca atccttgacc
    22501 acctgagtcc acaacgccaa cttctttcaa tactggaagc atgtctggtg ttttagctag
    22561 agctgtttta gcaccttcca aggctgcgcg catgacttca acagcgtcat ctgtttgctc
    22621 agcttttttc ttagcaccga tagcagctcc acgagaaact gttaaaatcg ttccttcaac
    22681 aggtttcatc actgccttat aggcaacttc cacacctgat tggaaggcca gagccaagtc
    22741 ttgacctgtt aactcgtctt tatccttgat agcttgggaa aatccacgga aaagctgaga
    22801 cgtaatcact cctgagttcc cacgcgcacc catcaaaagc cctttggcaa gaatgctcgc
    22861 tacttctcca actgtagaag ctggcttgtc tgcaacttct ttagcaccat tttcaatggt
    22921 cattcccata tttgtcccag tatctccatc tggaactgga aagacgttta atgaattgac
    22981 atattcagct tgcttattca agcgagttga tgcagcctgc accatttctt gaaataagct
    23041 agtagtaatt tttgacacgg ttattctcct acaactttga tattttgaat gtagacattt
    23101 acagtctgag cagtaattcc aagctggttt tccaagctaa aggcaacacg ctcttgaatg
    23161 ttttttgaca cttcactaat ctttgttccg tagcttaaca cggtatatac atcaactgca
    23221 atactgccat cttcggctgc ctttacgacg acacctttag aataattttc cttacctagc
    23281 agggcttgga aattatcttt gagggcattt ttactagcca taccgaccac accaaaaatc
    23341 tcagttgctg ctccacctac gacggttgca atcacttcat ctgttagttc gatttgacca
    23401 tcttttgtat taatttttac agtcatcctt tttacctcaa ctagttgata ctctatttta
    23461 tcatatttca gcccaagtgt aaaagcagaa tgatgtatca gcggatattt actctatttt
    23521 tcaaacgatg ttatacccac aataaaagaa aaaagaccct aaggtctcct ttgcttttat
    23581 tattaaacgc gttcaacttt acctgatttc aaagcacgag ctgaagccca aactttttta
    23641 ggtttaccat cgataagaac agtaactttt tgaaggtttg gttttacggc acgttttgtt
    23701 tggttcatcg cgtgtgaacg gttgtttcct gatacagtct tacgacctgt aaagtaacat
    23761 actttagcca ttgtgttttc ctcctattag atctaatata gcggatgtgc tagcaccaca
    23821 taccgtacta tgttatcaca ctttcttgtt ttttgcaagg gaattggaag attttttatt
    23881 tgtgtcttaa atcaggtctt gcatgacatt ttctgctctc cacatgccat tgttgattaa
    23941 cagaacacca gaattaaaat tatgtgtata aaaatcatct ctaactgcag ctaagggtat
    24001 agccgtcaag tccaaatccc acagctcatc tatcgatttt cttacaacaa tatctaaatc
    24061 caaatacagt acacgagact cgcttacata ctttggaata aaatacctaa aaaagccgca
    24121 tatgaaagtc cctcaaaggg gagacgataa cctttcagaa tactactgtc aatctaaaca
    24181 ttcacaatct cactattcaa agtctctagt cttttttcca tcaattggaa ccattctcgc
    24241 ggaaggtcat cattaaaaac ataaaactta agattataat agatgaacac aaagagattt
    24301 tattgttgtt tcaactttat ccatataagc attatctgca cctaagacaa tcgctttttt
    24361 ctcttctttc actctttatc tcatttcttt ttattcccat catatgtttc tacgtaacca
    24421 ttattttcgc ccattcgttc gtaaaaccat accagtggag attttagatg aagtcccatt
    24481 acggtttaca atttttacat tacgacacgg agttttacaa atcgatttca tttgccaaac
    24541 gtagttagta aggcagttag ctaggctacc tactttctgc tacgacggaa aaatccacaa
    24601 atcaatacca ttcgtggatt tttcctagtg aagcgtttag gtaagccgcc atagcggtta
    24661 ccgattatta gattacgaca cggagtttgg caaatcgatt ctatttgcca aacgtagtta
    24721 gtgaggcagt tagctagttc gccaaatagc gactagcgtc caacaatttg gaactttagt
    24781 tccaattgtt ggtactgagt cacatcttct cctctaactc tacgtctgga tacttgtccg
    24841 caaaccagcg gagggcaaag tcattttcaa agagaaagac tggttggtca aaacggtctt
    24901 tggctaagat attgcgactt gatgacatcc gttcatccaa atcctcaggc ttgatccaac
    24961 gaacggtctt tttacccatt gggctcatga ccacttccgc attatattct ccttccatac
    25021 ggtgcttaaa gacttcaaac tggagttgac ctacagcgcc tagcatgtac tcacctgttt
    25081 ggtaattctt ataaagctga acggctcctt cttgcactag ttgctcaatc cccttgtgga
    25141 aggatttttg cttcatgaca ttcttagcag aaactttcat gaaaatttca ggagtaaagg
    25201 ttggcaatgg ttcaaattca aatttgtttt tcccaactgt caaggtatcc ccaacctgat
    25261 aagtgcctgt atcgtaaacc ccgataatat cacctgccac ggcattggtc acattctcac
    25321 gactttccgc cataaactgg gtaacattag acagtttagc ccccttacca gtacgaggga
    25381 gattaacact catgccgcgc tcaaattcgc cagatacgat acggacaaag gcaatacggt
    25441 cacggtgacg agggtccatg ttggcttgga ttttaaagac aaagcctgag aaatccttgt
    25501 cataaggatc cacaatttca ccgtctgttt tcttgtgacc atgtggttct ggagcaaact
    25561 tgaggaaggt ttcaaggaag gtctgcacac caaagtttgt cagggctgaa ccgaaaaaga
    25621 caggcgtcaa ttctccagcc agaatagctt cctctgaaaa ctcattcccg gcttcattta
    25681 aaagctcaat atcatccttg acttgctcgt agaaaggatt gctaccaaaa agtttgtccc
    25741 catcttctag actagcaaaa cgctcatccc ctttataaag ctctaaacgt ttgttataga
    25801 ggtcatacaa gccctcaaag gctttcccca tcccgatagg ccagttcata gggtagctag
    25861 caatgcccaa gatttcttcc aattcttgta agagatccaa aggctcacga ccgtcacggt
    25921 ccagcttgtt cataaaggta aagactggaa tgccacgatg tttcacaacc tcaaacaatt
    25981 tcttggtttg agcctcgatc cccttggcag agtccacgac catgaccgca gcatccaccg
    26041 ccatcaaggt acgataggta tcttctgaga agtcctcgtg ccctggcgtg tctaagatat
    26101 tcacgcgctt gccgtcgtag tcaaattgca taacagatga agtaacagaa atcccacgtt
    26161 gcttctcgat atccatccaa tcagatttag caaaagtccc tgttttcttc ccttttaccg
    26221 taccagcctc acgaatttca cccccaaagt agagtaactg ctcagtgatg gttgttttcc
    26281 ccgcgtccgg gtgggagata atggcaaagg tacgacgttt cttaatttct tcttgaatat
    26341 tcataagttc tctttctttg attctctatt tttcttgttt caatagctga gaatgatttt
    26401 tacattggat tttaccattc ctttcaacac tccattatat cggattttag catttttttc
    26461 aatttctatt tcttttcact tccccctccc ttatttatag gaaaatatgg taaaatagaa
    26521 cagactaaaa atcatcattt cacgaaagga tgcaagatga aaattacgca agaagaggta
    26581 acacacgttg ccaatctttc aaaattaaga ttctctgaaa aagaaactgc tgcctttgcg
    26641 accaccttgt ctaagattgt tgacatggtt gaattgctgg gcgaagttga cacaactggt
    26701 gtcgcaccta ctacgactat ggctgaccgc aagactgtac tccgccctga tgtggccgaa
    26761 gaaggaacag accgtgatcg cttgtttaaa aacgtacctg aaaaagacaa ctactatatc
    26821 aaggtgccag ctatcctaga cgatggagga gatgcctaat gacttttaac aataaaacta
    26881 ttgaagagtt gcacaatctc cttgtctcta aggaaatttc tgcaacagaa ttgacccaaa
    26941 caacacttga aaatatcaag tctcgtgagg aagctctcaa ttcatttgtc accatcgctg
    27001 aggagcaagc tcttgttcaa gctaaagcca ttgatgaagc tggaattgat gctgacaatg
    27061 tcctttcagg aattccactt gctgttaagg ataacatctc tacagacggt attctcacaa
    27121 ctgctgcctc aaaaatgctc tacaactatg agccaatctt tgatgcgaca gctgttgcca
    27181 atgcaaaaac caagggcatg attgtcgttg gaaagaccaa catggacgaa tttgctatgg
    27241 gtggttcagg tgaaacttca cactacggag caactaaaaa cgcttgggac cacagcaagg
    27301 ttcctggtgg gtcatcaagt ggttctgccg cagctgtagc ctcaggacaa gttcgcttgt
    27361 cacttggttc tgatactggt ggttccatcc gccaacctgc tgccttcaac ggaatcgttg
    27421 gtctcaaacc aacctacgga acagtttcac gtttcggtct cattgccttt ggtagctcat
    27481 tagaccagat tggacctttt gctcctactg ttaaggaaaa tgccctcttg ctcagcgcta
    27541 ttgccagcga agatgctaaa gactctactt ctgctcctgt tcgcatcgcc gactttactt
    27601 caaaaatcgg ccaagacatc aagggtatga aaatcgcttt gcctaaggaa tacctcggtg
    27661 aaggaattga tccagaagtt aaggaaacaa tcttaaacgc ggccaaacac tttgaaaaat
    27721 tgggtgctat tgtcgaagaa gtcagccttc ctcactctaa atacggagtt gccgtatact
    27781 acatcatcgc ttcatcagaa gcttcatcaa acttgcaacg ctttgacggt atccgttacg
    27841 gctatcgcgc agaagatgca accaaccttg atgaaatcta tgtaaacagc cgaagccaag
    27901 gttttggtga agaagtgaag cgccgtatca tgctgggtac tttcagtctt tcatcaggtt
    27961 actacgatgc ctactacaag aaggctggac aggtccgtac acttatcatt caagatttcg
    28021 aaaaagtctt cgcggattac gatttgattt tgggtccaac tgctccaagt gttgcctatg
    28081 acttggattc tctcaaccat gacccagttg ccatgtactt agccgaccta ttgaccatac
    28141 ctgtaaactt ggcaggactg cctggaattt cgattcctgc tggattctct caaggtctac
    28201 ctgtcggact ccaattgatt ggtcccaagt actctgagga aaccatttac caagctgctg
    28261 ctgcttttga agcaacaaca gactaccaca aacaacaacc cgtgattttt ggaggtgaca
    28321 actaatgaac tttgaaacag tcattggact tgaagtccac gtagagctca acaccaattc
    28381 aaaaatcttc tcacctactt ctgcccactt cggaaatgat caaaatgcca acactaacgt
    28441 gattgactgg tctttcccag gagttctgcc agttctcaat aaaggggttg tcgatgccgg
    28501 aatcaaggct gctcttgccc tcaacatgga catccacaaa aagatgcact ttgaccgcaa
    28561 gaactacttc tatcctgata accccaaagc ctaccaaatt tctcaatttg atgaaccaat
    28621 cggatataat ggctggattg aagtcgaact agaagacggt acgaccaaga aaatcggtat
    28681 cgaacgtgcc cacctagagg aagacgctgg taaaaacacc catggtacag atggctactc
    28741 ttatgttgac ctcaaccgcc aaggggttcc cttgattgag attgtatctg aggcagatat
    28801 gcgttctcct gaagaagcct atgcttatct gacagccctc aaggaagtta tccagtacgc
    28861 tggcatttct gacgttaaga tggaggaagg ttcgatgcgt gtggatgcca acatctccct
    28921 tcgtccttat ggtcaagaga aattcggtac caagactgaa ttgaagaacc tcaactcctt
    28981 ctcaaacgtt cgtaaaggtc ttgaatacga agtccaacgc caggctgaaa ttcttcgctc
    29041 aggtggtcaa atccgccaag aaacacgccg ttacgatgaa gcgaataaag caaccatcct
    29101 catgcgtgtc aaggaagggg ctgctgacta ccgctacttc ccagaaccag acctacccct
    29161 ctttgaaatt tctgacgagt ggattgagga aatgcggact gagttgccag agtttccaaa
    29221 agaacgtcgt gcgcgttatg tatctgacct tggtttatca gactacgatg ctagtcagtt
    29281 gactgctaat aaagtcactt ctgacttctt tgaaaaagct gttgccctag gtggtgatgc
    29341 caaacaagtc tctaactggc tccaagggga agtcgctcag ttcttgaata ctgaaggtaa
    29401 aacactggaa caaatcgaat tgacaccaga aaacttggtt gaaatgattg ccatcatcga
    29461 agacggtact atttcatcta agattgccaa gaaagtcttt gtccatctag ctaaaaatgg
    29521 cggtggcgcg cgtgaatacg tggaaaaagc aggtatggtt caaatttcag atccagctat
    29581 cttgatccca atcatccacc aagtctttgc cgataacgaa gctgctgttg ccgacttcaa
    29641 gtcaggcaaa cgtaacgccg acaaggcctt tacaggattc cttatgaagg caaccaaagg
    29701 ccaagccaac ccacaagttg cccttaaact acttgcacag gaattggcga agttgaaaga
    29761 aaactagaca gaacaaaacc agccctaagg ttggtttttt cttctctccc aactcccaat
    29821 aactattttg gctttatttc cagagtattt tatggtaaaa tgaagagtaa taatatttat
    29881 taaagaggta aaaacatgat tgaagcaagt aaattaaaag ctggtatgac ctttgaaaca
    29941 gctgacggca aattgattcg cgttttggaa gctagtcacc acaaaccagg taaaggaaac
    30001 acgatcatgc gtatgaaatt gcgtgatgtc cgtactggtt ctacatttga cacaagctac
    30061 cgtccagagg aaaaatttga acaagctatt atcgagactg tcccagctca atacttgtac
    30121 aaaatggatg acacagcata cttcatgaat acagaaactt acgaccaata cgaaatccct
    30181 gtagtcaatg ttgaaaacga attgctttac atccttgaaa actctgatgt gaaaatccaa
    30241 ttctacggaa ctgaagtgat cggtgtcacc gttcctacta ctgttgagtt gacagttgct
    30301 gaaactcaac catctatcaa aggtgctact gttacaggtt ctggtaaacc agcaacgatg
    30361 gaaactggac ttgtcgtaaa cgttccagac ttcatcgaag caggacaaaa actcgttatc
    30421 aacactgcag aaggaactta cgtttctcgt gcctaatctc tagaaagagg tcattctatg
    30481 ggaattgaag aacaacttgg cgaaatcgtt atcgccccac gtgtacttga aaaaatcatt
    30541 gctatcgcta ctgcaaaggt agagggtgtt cactcttttt caaacagatc agtgtctgat
    30601 accctttcaa aactttcact cggccgtggc atttatctta aaaacgtgga cgaagaactc
    30661 acagcagata tctatctcta ccttgagtac ggagtaaaag ttcctaaggt agcggttgct
    30721 atccagaaag ctgtcaaaga tgccgtccgt aatatggctg atgtagaact cgctgctatc
    30781 aatattcacg ttgcaggtat cgtcccagat aaaacaccaa aaccagaatt gaaagatcta
    30841 tttgacgagg acttcctcaa tgactagtcc actattagaa tctagacgcc aactccgtaa
    30901 atgcgctttt caagctctca tgagccttga gttcggtacg gatgtcgaaa ctgcttgtcg
    30961 tttcgcctat actcatgatc gtgaagatac ggatgtacaa cttccagcct ttttgataga
    31021 cctcgtttct ggtgttcaag ctaaaaagga agaactagat aagcaaatca ctcagcattt
    31081 aaaagcaggt tggaccattg aacgcttaac gctcgtggag agaaacctcc ttcgcttggg
    31141 agtctttgaa atcacttcat ttgacactcc tcagatggtt gctgttaatg aagctatcga
    31201 gcttgcaaag gacttctccg atcaaaaatc tgcccgtttt atcaatggac tgctcagcca
    31261 gtttgtaaca gaagaacaat aaaaagaaaa agtgtttgat agatatcaaa cacttttttc
    31321 tttgcctccc actatctaaa aaaatgataa tagatataat tgtaaacaaa aatccagata
    31381 ggttttgcat gattgagaaa gttaaaaaaa ctatggcaga gaatcgttaa tctcagattg
    31441 tcggtagaac gataaacaag ggcaaaaaag aaaccaatca gactataata taataaacta
    31501 attggatctc tgtgagatag tatcaaatgg ctaatcccaa agatgatagc agataggata
    31561 acatccaaat agtacttgga ctagggaaag aaggtattca taaaataccc tctatcaaga
    31621 gtctcctcaa aaacaggacc gatgattaca ggcaggacaa aagataagat agtcgataaa
    31681 aaggttggtt gtccatttga aaaaagcacg gtaaaatact catcatgaat attcctatga
    31741 ttaatcaaat gagcatagcg tgcccaaaaa ttaccgagaa tctgataaac cacataagtt
    31801 gcaaataagt agaagacaaa tgaccagttc cagctctttt tctcaaagat aaagagcatc
    31861 tttttctttt ttaacctcca aattaataga aggaaacttc ccactaatcc cattgttaaa
    31921 ataagagaat agacatcagc tcctaaccct aaaatgatcg tcacatacaa tccaattgtt
    31981 tgtggtaaat aggtagatag taaaataata agcaaaaata ttccaaattg tcttagtttt
    32041 tttgtgtttc tcatcgtact tttttgaaag attaccctgc tcggaagccg tacttccaag
    32101 catctatata agaattaagt gccccttgcc tcatataggg agcaaattct ctataatata
    32161 accatctact atatccatct tcccaaacag caagaccacc tgaagtttgc tccaagtcct
    32221 cagttgaaag aactgtaaat gtatttgtac ctgtcattgc aagtaccttc ttaaaataga
    32281 ttgttgtagg ttcacattta tagtatattt ctttttttgt ctattttata gcccatctcc
    32341 tcaactggca atttttcgac ctgaattaca tttttccata aaaaatgaga cctttctagt
    32401 ctcatttagt cattcttagt attttctaaa tcgttgatag cgttcttcca gcaactcttc
    32461 tagcggtttt tgtgaaagtc tagccagctc cgtttggagt tcttttttga cactcttaat
    32521 cagttcttta ctagaaagtc ctatttcaga aatcacctta tccaccacgt ccatttctaa
    32581 cagttcatgc gaagtgattt tcatcagttc tgctgcttcc atagcgcgag taccgtcctt
    32641 ccataaaatg gaagcaaagc cttctggact gagaatggca tagatagaat tttccagcat
    32701 ccagacacgg tccgcgacag ctagagccag agccccgcct gaaccacctt caccgataat
    32761 aatggcgata ataggaactt tcaggtcact catttccatg agattgcgag cgatagcttc
    32821 cccttgacca cgttcttccg ctccgacacc aggataagca cctgctgtat tgataaaggt
    32881 cacaactgga cggccaaatt tctcagcctg tttcatcaac cgcagtgcct ttcggtagcc
    32941 ttctggatgt ggttggccaa aattccgttt gaggttgtct tgcaaactct tgcctttttg
    33001 gataccaacc actgttacag cttgatctcc aagccaacca ataccaccaa caactgcacc
    33061 atcatcacga aaagaacggt caccatgtaa ttggataaat tcatcaaaaa tgcctgtcgc
    33121 aaagtccaag gttgtcaagc gactctgctc acgcgcttct ctgactattt ttgcaatatt
    33181 catctaggac tccctccatg caatctgact aggctagcaa tcgtatctgg taagtctctt
    33241 cttttgacaa tagcatccac aaagccatgt tctaatagga attctgcctt ttggaaatcc
    33301 tcaggcaagc tttcacgaac cgtattttca atcacacgac gcccagcaaa accaaccaag
    33361 ctctgtggtt cagccagaat gatatcgcct tccatagcga aagaagctgt cacaccacca
    33421 gtcgttggat ctgtcaaaat ggtcaggtaa aagagaccag catttgaatg gcgtttaacc
    33481 gccgcagaga tcttagccat ctgcatgaga ctcatgattc cttcctgcat acgggctcca
    33541 ccagaggctg tgaataggac aactggcaat ttttcgacag tcgcatactc aaacaaacga
    33601 gtgatttttt cacctacaac cgtacccata gaagccatga taaagttaga atccataatc
    33661 ccaagagcca cagtctgacc tttaataaga gcagttcctg tcacaacggc ttcatgcaga
    33721 cctgtttttt cacgcataga tgccagtttc ttttggtaac cagggaaatg caagggatcc
    33781 ttgctttcaa tccctgtaaa caattctttg aaggttccca tatcaatcgt caaagccaag
    33841 cgttcttggg cagaaatacg aaaggtatag ctacagtgcg gacagatacg ttcacttccc
    33901 agatccttct gatagatggt atgcttacag cctggacact gggaaaataa ttcatctgga
    33961 acctctggct tagcttgagg tttttcccta accgaacgat tgggattgat tcgaatatac
    34021 ttatcttttt tactaaatag agccattgat tccccttttc ggtttaaact cttaaagtca
    34081 ttttattctt tttcttgata tttaggtaag aaggtttcca tcaagaagga agtatcataa
    34141 tccccagcaa tgacattgcg atctgaaatg aggtcaagct ggaaatctgc attggtctgc
    34201 actccttcaa tctctaattc atagagggca cgttgcattt tcatcaaggc gtcaaaacga
    34261 ttttcgccgt gtactatgat tttggcaatc atactatcat aataaggcgg aatggtataa
    34321 cctggataaa ctgctgaatc cacgcgcaag ccaactccac cacttggcag atagagatta
    34381 gtaatcttac ctggacttgg agcaaagtta aaggctgggt tttctgcatt gatacgacac
    34441 tcgatggcat gaccgcgtag gacaatatct tcttgcttaa cagacaaagg ctgacctgcc
    34501 gcaatgcaaa tctgttcctt aacgatatca acacctgaaa caaactctgt tactggatgt
    34561 tctacctgaa cacgagtatt catctccatg aaatagaaat tgctacttgc ttcatcaaga
    34621 agaaattcaa tggttcctgc attctcatag ccaacaaact ctgccgctcg aacagcagca
    34681 gcacctattt catgacgcag cgtttttccg attgcaatcg agggactttc ttccaaaacc
    34741 ttttggttat tcctttgaag agaacaatcc cgttcaccca agtgaatcac atgtccatgc
    34801 tcatcaccta ggatttgaac ctcaatgtgc cgagctggat agataacccg ttctatgtac
    34861 atggcaccat tgccataatt ggccttggcc tcactagagg cagtttcaaa ggcagaaacg
    34921 aggtcatctg gttttttaac cttacgaatc cctttaccac ctccacctgc tgaagccttg
    34981 agcataacag gatagccaat tttttcagca acaatcaaag cttcttcaga gttatgcact
    35041 tctccatctg aacctggtat aacaggcaca cctgctttaa tcatctgagc acgcgcattg
    35101 atcttatccc ccatcatatc cataacatga ccagatggac cgataaactt gatacctact
    35161 tcttcacaca tggtcgcaaa tttggaattt tcactgagaa atccaaaacc agggtgaata
    35221 gcttctgcct cagtcaagac tgcagctgat agaactgcat taatattgag ataagactct
    35281 gttgccttgc caggaccaat acaaactgct tcatctgcca aaagcgtatg aagagcttcc
    35341 ttatcagcag ttgaataaac cgctaccgtc gcaatcccca attcacgtgc cgcacggata
    35401 atacgaaccg caatttcacc acgattggca attaaaattt ttcgaaacat ggagaacctc
    35461 cttagttccc aattgcaaaa gtaagggtac cactggctgc aagcttgcca tccacttcag
    35521 cctttgcttc aaccacagct atggtgccac gacgttttac aaaagtcgct gtcataacca
    35581 attggtcgcc tggtacaact tgcttcttga acttaacctt gtccatacca gcgtaaaaga
    35641 ccagttttcc tttattttca ggttttgata actccaacac accggcagtt tgcgccaagg
    35701 cttccataat cagaacacct ggcataactg ggtattgagg aaagtggccg ttaaagaaag
    35761 gttcgttaat ggtcacattt ttgatagcaa caatggtatc ctcgctcact tccaagacac
    35821 ggtccactag aagcatagga taacggtggg gaagagcttc tttgattcct tgaatatcga
    35881 tcatttgata cgtaccaatc ctttaccaaa ctcaaccatt tcttcgttag agacgagaat
    35941 ttccgttacc acaccatcct taggagctgg gatttcattc atgactttca tggcttcgat
    36001 aattaccaat gtttgacctt ttttgacact atcaccaact gtaacgaagg caggtttatc
    36061 tggtccagca gccaagtaaa ccactccaac aagtggactc tctacaagat ttccctcagt
    36121 agccacactt gcttcagctg gagctggaac ttcttctgct acagtctctg ctggagcaga
    36181 tgtaggagct actggactcg gtgttgctag aacgggtgct ggagcgactt gagttgcaac
    36241 ttcaggcaca ggtcttgctt cattcttgct aaactgcaac tcatccgtcc catttttata
    36301 agaaaattct ctcaaacttg actggtcaaa ttgagtcatc aagtctttaa tatcgtttaa
    36361 attcatactt atctattctc ccaacgtttg aaagcaagaa ctgcattgtg gcctccaaaa
    36421 ccaaaagtat ttgaaatagc gtatggaatt tctttctcca agccttgtcc ataaacgaca
    36481 ttagcttcga tataatctga tacttcactt gtcccagctg tcattggtac aaagttatga
    36541 cgcatagctt cgatggtgac gatagcttct actgcacccg cagcccccag caaatgtcct
    36601 gtaaaagact tggttgatga tacaggtact tccttaccaa gaacagctac gatagcacca
    36661 ctttctcctt tttcattggc aggagttgac gttccgtgag cattgacata ggctacttgc
    36721 tctggagaaa tctcagcttc ttccaaggct agtttgatgg ccttgatagc tccctgacct
    36781 tctggatgtg gagaagtcat gtggtaggca tcacaagtat ttccgtaacc aaccacttca
    36841 gccaggatag tagctccacg tttttcagcg tgttcaagac tttctagaac caacatccct
    36901 gaaccttcac ccataacaaa cccattgcga tccttatcaa atgggatcga agcacgagtt
    36961 ggatcctctg tagtagagag agctgttaag gcttggaaac cagcgatggc aaaaggtgtg
    37021 atagaagctt ctgttcctcc caccaacatc acatcttgga aaccaaactt aatggagcgg
    37081 aaggcatccc caatcgcatc atttgatgaa gagcaggcag tattgataga tttacaaaca
    37141 ccgtttgcac caaaacgcat ggctacattc ccagaagcca tatttggtaa agcttttgga
    37201 agagtcattg gtttgacacg tttgggtcct ttttcatgaa ggcgaagtac ctgatcttca
    37261 atttccttga ttccaccaat accagatgca acgataacac caaaacgatc cctattaaga
    37321 gcctctacat caagattggc atgatttaca gcctcttggg ctgcatacaa ggcatataaa
    37381 gaatagttat caaaacggtt ggtatctttt tttacaaagt atttatcgaa cggaaaatct
    37441 tggatttctg ccgcattatg cacatcaaag tcactatgat caaattttgt aatgccacca
    37501 atgccgattt tcccagttgc taaactattc caaaattctt ctggtgtatt tccgattgga
    37561 gatgttactc cataacctgt taccactact cgatttagtt tcattctttt cacctctagc
    37621 tttcgctaca tacttaagcc accatcaatg gcaatcactt gaccagttag ataatcttgg
    37681 cctgctaaaa atactgtcaa atctgcaacc tgctctgcct gcccaaattc tttcatcgga
    37741 atctgagcta gtgtagcttc cttaatctta tctgataaga tagctgtcat atcagactca
    37801 atcattcctg gagcaatcac attgactcgt atattccgac tagcgacctc gcgtgccaca
    37861 gacttggtaa agccaatcaa gccagcctta gaagcagcat agttagcttg accaatattc
    37921 cccatcaaac caacaacact agacatatta atgatagcac cttctctggc tttcatcatc
    37981 ggtttcaaga ctgattgtgt catattaaag gcaccagtca gattgacctt gagcactttt
    38041 tcaaaatctg cttctgtcat cttgagcata agagtatctt gggtaatccc tgcattgttg
    38101 accaaaacat ctactgaacc cagttctgca atagcttgat caatcatacg cttagcgtct
    38161 gcaaaatctg atacatctcc tgaaatggga accaccttga taccatagtt tgaaaactca
    38221 gcgagcaatt cttctgagat tgccccacga ctgtttaaga caatgttggc tcctgcttga
    38281 gcaaacttgt gggcgatggc aagaccaatt ccacgactcg aacctgtaat aaagatattt
    38341 ttatgttcta gtttcatttt tttcctttca aaacttctac ttattttagt ctatttttct
    38401 aaaagtgcta ctaaactcgc ttgatcttcc acatgagcta agtgagcagt ttgatcaatt
    38461 tttttaacaa agcctgacaa gactttcccc ggtccaatct ctataaagtt gcttatgcct
    38521 gcttcttgca tgaccccaat actttcatag aaacgaacgg gttccttgac ctgacgcgtc
    38581 aagagctgag caatgtcctc tttttgcatc acagcagctt ctgtattgcc gactagggga
    38641 caagtaaaat ctgaaaaact tacctgagct agagtttcag ctagtttctg gctagcaggc
    38701 tcaaggagag cggtgtgaaa gggacctgac accttaagag gaatcaagcg tttggcacct
    38761 gcttcttgca aaagttcaac cgctcgatca actgcaacca cttctccagc aatgacgatt
    38821 tgtgcaggtg tgttatagtt ggctggagta accactccaa gttcagaagc tttttgacag
    38881 gcttcttcaa tgacctctac tggcgtattg agaactgcta ccatcttgcc agagtcagca
    38941 ggagccgctt cttccatata ggctccacgc ttagctacca aggcaaccgc atcttcaaaa
    39001 tccaaggcgc cgcttgccac caaggcagag tattctccaa gagacaaacc agcaaccata
    39061 tcaggctgat agcccttttc ttgcaataaa cggtagatag caaccgaagt cgctagaatg
    39121 gctggttgcg tatagcgggt ctgattgagt ttgtcttctt ccgtatcgat gagataacgc
    39181 aaatcataac ctagtacctg gctcgctcga tcaatcgttt ctttaacaat cggatactga
    39241 tcatagaaat cccgtcccat ccctagatac tgggcacctt gaccagcaaa taaaaaggct
    39301 gttttagtca tttcttacaa ctcctgtcca gcgagaggct tcttcttgaa ttttcttagc
    39361 ggctccgtaa tacaaatctt ttaggatttc ttcagctgtt tcttctttag aaacaagccc
    39421 tgcgatttga cctgccataa cagagccacc atccacatca ccgtgaacaa ctgctttggc
    39481 tagagcacct gctcccattt gttcaaagat ttctaaatca ggatcttctt gcttaaaggc
    39541 atctttttca gccagttcaa aatctctagt caactgattt ttaatagcac gaacagcatg
    39601 accaaagtgc tgagctgaaa tcgtagtatc aatatccctt gcttttaaaa ttttctcctt
    39661 gtagtttgga tgggcattcg actcttttgc aactacaaac cgtgtcccca cctgtacagc
    39721 ctctgcacct agcataaagc cagccgcagc accttcacca tccgcaattc ctcctgcagc
    39781 aataacagga atagatacag ctgtggctac ctgtcgcacc aaagtcatgg ttgttaattt
    39841 accgatatgc cccccagctt ccattccttc tgcaataaca gcgtctgcac cgattttttc
    39901 catgcgttta gctaaagcaa cactaggaac gacaggaata acgattatcc cagcttcatg
    39961 gaaacgttcc atatacttgc ttggatttcc tgctcctgtt gtgacaactt taacaccttc
    40021 ttcaataacg agatccacga tatcttccac aaagggagat aagagcatga tgttgacccc
    40081 aaagggttta tcagtcaatg atttgatttt atcaatattg gccttgacaa cttctttcgg
    40141 ggcatttccc ccaccgataa ttcctaatcc tccagccttg gaaacagccc ctgccaaatc
    40201 accatcagca acccaggcca tccctccttg gaaaatagga tagtcaatct tcaataattc
    40261 tgtaatacgc gttttcatag tgcctccaac cttccttgct tacgtaatag ttcgatttca
    40321 ccataatttg acagtcaaac tattacctaa acaagaggga gtgggtttct ccctactcct
    40381 tctacttaat attctgctta ttttgcttgc tcttcaacgt aagcaaccaa gtcaccaact
    40441 gttttcaagt cattttctgc ttcgatttgg atatcaaaag catcttcgat ttctgagatt
    40501 acttggaaca agtccaatga atctgcgtcc aaatcatcaa aagttgattc aagtgttact
    40561 tctgatgcgt cttttccaag ttcttcaacg ataatttctt gtactttttc aaatactgcc
    40621 atgataggac tcctttaaaa taaatagttt ttttataaca atgtgttcac cacatgatta
    40681 cctaaattgt aagaatgagc gtgccccagg tcaaacctcc accgaagcct gatagaagaa
    40741 cagtctggct accatctaaa gggatgagac cttgttctac acactctgaa agtaaaatcg
    40801 ggatactggc tgcactggta ttgccatatt ccatcatatt ggctggaagt ttggctcggt
    40861 caacaccaat ttttctagcc atcttatcca aaatacggtc attggcttga tgaagtagca
    40921 gataatccaa gtctgtcacc tctataggag attcatcaat agtctgcttg atagacttgg
    40981 ctacatctcg aatggcaaaa tcaaagactg tgcgtccatc catcttcaaa aatgaatctg
    41041 cactttcttg atctgaaaat ggagaatgca aacctgaatg cccataagtt aaacactcgc
    41101 tgcgacttcc atcgctattg agactctcag ctaagaaatg ctcttgctcg ctagcttcta
    41161 acaagacacc accagcacca tctccaaaca acacagctgt tgatcgatcc gaccaatcga
    41221 ctgccttaga gagggtttca ctaccaatca ccaagccttt ttgaaagcga ccagaagcga
    41281 taaacttttc agcagttgaa agagcaaata caaatccact gcaagccgcg gttaagtcaa
    41341 aagcaaaggc tttattagca ccaatattag cttgaacacg agcagctgta gagggcatca
    41401 tcgaatctgg agtaatggta gctaggatga taaaatccag ttcttttcct gttattccag
    41461 cttttgccat cagtttctta gcaacctctg tagccaaatc actggtagat tctgttcttg
    41521 aaatatgcct ttgtcgtatt cccgttcgac ttgaaatcca ctcatcattg gtatccataa
    41581 tctgagccaa gtcgtgattt gtaaccactt gctctggcac ataatgagca acctgactta
    41641 tttttgcaaa agccattatt tcaaatcctc caaaaattgg taaagattag tcaagccttt
    41701 acccatgaca gcaatttctt cctcgctcat gccatcaata attttttcta ccatggcctt
    41761 gtggaagcgt ttatgcagtc tatgaatcaa gcgacccttc tttgtcaaat gcagatgcac
    41821 cacacgacga tcctgttctg accgaactcg ctcaatgtag cccttacgct ctaaattgtt
    41881 caaacttgtc gtaacagttc caagagttac catcaactct tttgacactt gacttggagt
    41941 cacatctgga gccttaccga tgacatcaat cgtatgcatt tctttgatgg agatatcctt
    42001 aaaacgacta cctctcaagt tcacttcctc aattacaagg acattgttaa atatagatgt
    42061 taaatattca ttgattcgtt ggtagtccat ttttcatatc cctccttctt caaaaaactt
    42121 ttacaatcaa aacatttgac agaaagaatt atatcaaaat tcaaagaatg atgcaagtat
    42181 tttttatttt cctgtaaatt taggtcttct tctctccgaa tgagctcgca ctccttcttt
    42241 gaaatcctct gtttgagcta aggatttctg taggttcagt tctaaagtag cgtaaccctg
    42301 ccagtcttta aattggctct cccaaaccaa cttcttaatg gcagcatagg aattacttga
    42361 agcacgtctt aattttttaa gaagctgttc tctcgtcttt tcaagttttt cagcttcaga
    42421 aacgcggtaa accaaccccc attctagggc tttttctgcc gttaaagcct ctcctgtcat
    42481 agctaattga gcagcacgcg tcacaccgat actgcggctc aagagatgaa ttccccctgc
    42541 atctggagcc aaaccaacac caacaaaggc ttggataaac ttagccttat ccgtcgccaa
    42601 acagaaatct gccgcaacag ccatattcgc tgcggcacct gcaacagcac cgtcaacttc
    42661 cattaaaaca ggtttggcta tttgcttgat tttataagaa atcgtattga ccaactctgc
    42721 gatttttgtc aatgatggaa tatcatcctc atccactgcc cgcttcatct ctaccaaatc
    42781 tcccccaact gagaagacct ttccattggc attgattaag ataaaatgca cagctggatt
    42841 ttcttctgcc aaagtcagag cttctaaaat ctcctcacac atgggaatat gaaaaccatt
    42901 tgcgacctca ggacggttca aggtaaggat tgccaagtcc tcttcaagct gataaataat
    42961 gtgttccatc agggctcctt tttattttat aagcagttta tactcttcga aaatctcttc
    43021 aaaccgcgtc agcttccatc tgtaacctca aaacagtatt ttgagctgac ttcgtcagtc
    43081 ttatttacaa cctcaaagca gtgctttgag cagtctgcgg ctagcttcct agtttgctct
    43141 ttgattttca ttgagtgtta aattatttca ctgtcaaagt atatcttttt taggagcaga
    43201 aagcaagaaa aaatcgactg aaagtgtctc agccgataag aaaggctcgc tttaggctag
    43261 aaagcatctt attttcttca ttgaaaaaag cctttctttc tgctataatc gtataaaata
    43321 cttactttag gagttcttat gaaagttgtt aaatttggag gtagttctct tgcctctgct
    43381 agtcaattag aaaaagtttt aaacatcgtc aaaagcgatt cagagcgtcg ttttgtagtc
    43441 gtttctgcgc ctggtaaacg caatgctgaa gatactaagg ttacggatgc cctgattaaa
    43501 tactaccgcg actatgttgc gggtaacgat attagcaaga gccaaagctg gattatcgac
    43561 cgctatgctg ctatggttag tgaattggga ctaaaaccag ctgtgctaga aaaaatttct
    43621 aaaagcattc acgccttggc cactcttcct attgaagaaa atgaatttct ctacgatact
    43681 ttcctagcag ccggtgaaaa taacaatgcc aaattgattg ctgcctactt taaccaaaat
    43741 ggtatcgatg cacgctatat gcaccctaga gaagctggga ttgtggtcac aagtgaacct
    43801 ggtcacgctc gcatcattcc atcaagttat gacaagattg aagaattgac aaacaccaat
    43861 gaagtccttg tcattcctgg tttctttggt gtcactaagg aaaatcaaat ctgtactttc
    43921 tcacgtggag gatctgatat tacaggttct atcattgctg ctggtgtcaa agctgacctc
    43981 tatgaaaact ttacggacgt tgatggtatc tttgcagccc accctggtat tatccaccaa
    44041 ccacactcga ttcctgagtt gacctaccgt gaaatgcgcg agttggccta tgcaggcttc
    44101 tcagtccttc atgacgaggc tcttcttcct gcctaccgtg gaaaaattcc tctggttatc
    44161 aagaatacca acaaccctga ccatccaggt actcgtatcg ttctaaaaca cagtaatgat
    44221 gaatttccag ttgtgggaat tgctggtgac tcaggctttg tcagcattaa tatgtcgaaa
    44281 tacctcatga accgtgagat tggatttggc cgcaaggttc tgcaaatcct ggaagaactt
    44341 aacatcggtt gggaacatat gccaacaggt atcgacgatc tttctatcat tctccgttct
    44401 cgccaactaa ctcccatcaa ggaagaagaa atcctgcgtc agttggttca aaaggctaaa
    44461 gtagatcatg cagaaatcga acacgacctt tctatcatta tgattgttgg tgaaaaaatg
    44521 aagagccata tcggagtgac tgctactgcg acacgcgctc tatctgaaaa caaaatcaac
    44581 atccagatga tgtctcaagg ttctagtgaa gtttctatta tgtttgttgt caataaagac
    44641 caagagaaag cagcaattaa agccctctac tatgcctttt ttggagaaag taaggaagac
    44701 taagcatggc tcaatcactt aacaaaacag tactcctcag tacgacaggc acttcctacc
    44761 tctctatcgc tgggaaagtt gggaaattcc ttgtcggaga tcaggctttg gaattttacc
    44821 cagatgtcaa tgtcgaacaa tttatccaga ttccttggag ccatatcaat cagattggag
    44881 ccaatgtcac tggacgcaaa gtcagccgcc acttcgaagt ctttacagac aaaggaaaat
    44941 tcctctttgc ttcaaaagac tcaggtgcca ttctcaaaat tgcacgcgaa aaactaggca
    45001 atgacaaggt cgtcaaactt ccgaccctga ttcagacaat tagccaaaaa tttaaaaatc
    45061 tatttgcaaa aaagtagaaa ctttagtata atcatagcaa cggataagta ggttatcttc
    45121 ttctttcaga aagtctgcgg gtactgcgag cagatagggg ggataggtga aattctaccg
    45181 ttagtaacaa ttacatacac aatcaagtgc acacctgtga agttggatgg aaccgtggcc
    45241 ctgccactcc aacgttttgt caggcgtgct tttttcataa aggagttctt atgttagata
    45301 tcaaacgtat tcgtacagat tttgaagctg tcgcagaaaa attagctaca cgtggtgtag
    45361 atgctgctgt cttgaatgaa atgaaagaaa tcgatgctaa acgtcgtaac atcttggtca
    45421 aggttgaaac tctcaaagca gaacgtaaca cagtttctgc tgagattgcc caagctaagc
    45481 gcaacaagga aaatacagat gacaagattg ctgccatgca aaatctatct gctgaggtta
    45541 aagccttgga tgctgaattg gcagaaatcg atgctaaatt gacagaattt acaacgactc
    45601 ttccaaatat cccagctgac agcgttcctg ttgggactga cgaagacgac aatgtggaag
    45661 ttcgccgttg gggtactcca cgcgagtttg acttcgaacc taaagctcac tgggatctcg
    45721 gtgaagacct tggtatcctt gactgggaac gcggtggtaa ggtaacaggc gctcgcttcc
    45781 tcttctataa aggcctcggt gctcgtttgg aacgtgctat ctacaacttt atgttggatg
    45841 aacatggaaa agaaggctat actgaagtca tcacacctta catagtcaac catgattcta
    45901 tgtttggtac tggtcagtat ccaaaattta aggaagatac ttttgaactc agcgatacca
    45961 actttgtctt gattccaact gctgaagttc ctctgacaaa ctactaccgt gatgaaatct
    46021 tagacggcaa agatcttcca atctacttca ctgccatgag tccgtcattc cgttctgagg
    46081 ctggttctgc cggtcgtgat acgcgtggct tgatccgttt gcaccaattc cacaaggttg
    46141 aaatggtcaa atttgccaaa ccagaagaat cttacgaaga attggaaaaa atgacagcca
    46201 acgctgaaaa cattcttcaa aaactcaacc ttccataccg tgtcgttgct ctctctactg
    46261 gagatatggg cttctcagct gcgaagactt acgacttgga agtgtggatt ccagcacaaa
    46321 acaattaccg tgaaatctca agctgttcaa acacagaaga tttccaagcc cgtcgtgccc
    46381 aaatccgtta ccgtgatgaa gcagatggca aggtgaaact ccttcatacc ttgaacggtt
    46441 ctggacttgc agttggacgt acagtggctg caattcttga aaattaccaa aatgaagatg
    46501 gttctgtgac catcccagaa gcacttcgtc catacatggg tggagctgaa gtcatcaaac
    46561 cataaaaaat aaggtttagc tatttctagc tagacctttt ttcgtaacca aatcagataa
    46621 gcacctagta caaagaataa aatagttagg catataatgg tttcagccaa taccaggtaa
    46681 tccagaaatg gaagtttcaa aattccctga gccatcttga gcgaggtcgc tgtgataatg
    46741 gttgggaagg tgagggctga gaaggctggt tgaaaacctt gttttaaaat gttgggcaga
    46801 cgagttaaaa caaagaaaaa gaaggattga gaagccaaaa tcatgacaat caagacccaa
    46861 gtcggcaggc tggttcctcc tactcgaact agagaagcca agagtagaga gaaaggagca
    46921 cagtagattc cttcttgtcc aagcaaggct agtgggagtg gatgtttctt taaatcgcta
    46981 taaataaggg gatagagata gaaggtcaag agaaaaccaa aactcaaggt cgcataggca
    47041 atttcgataa tacctaccag aggataggtc aaggcagcca ctgctatccc cacatagaga
    47101 accgtccagc ttggagtggc atgaaccctc cgccctggac aagcaaactt gatggtaaaa
    47161 ccagcaatca aggtcaaatc caagagaaat gaaaaccacc aaatcccttg tgctaccaaa
    47221 ggaagataag agaatacgcg aaagacatag gtcgataaaa tcatcccagc cataggaaag
    47281 gttgccattc ctgacaaaag agggggcttg gtcaattctt gcttggtttc tttccaatta
    47341 aagagatgca gaattagaaa gtaaatccat aaaaccaaac cagtcagact aaaaagatgg
    47401 gatagaaccg gcaacgtatc taaaataaga tttccagctc ctgccaaacc tagcaaacaa
    47461 cctgaaaata ctaaggggag ttttttcatc ctaacctcca ataatcatgt tagtttcagt
    47521 ataacataaa agcgcttaaa tgaggattta aaaaaacgaa gtccgattat ttcagacttc
    47581 attttactca gatatgaatt aggcataagg ttgcaattct ggattaattg gtgtattagc
    47641 taagttgttg gcatagttac agaggattgc taggctgaca ccaaaaacca catccaaggc
    47701 attttgttga gtgtagccag cttctaaaaa ctcagacaag gcttcatctc ctacacgacc
    47761 cttggtattg ataactgcca aggtaaactt agctagggta tccaatttag gatctgtttc
    47821 aattggagta cgattgcgaa gagcttgaat caagtcatca ttcatctgga tttgtttgat
    47881 ggaaaaggct gtgtgacctg cgacacagaa ggcacaacca ttggtcacgg ctgccgtgat
    47941 ttgcaccact tcacgctcaa cgggtgtcag gctgttgcga cggtggatag atgagacaat
    48001 ttggtaggct tctaaaacag tcggggcatt ggccaagaga ccgattaggt tgggaatata
    48061 gccattgttg tctttttcta ctgtttcaag aatttctttc acttctgctg gtgctgactc
    48121 tactgtatgg atagtaaatg ttgtcataag atacctcttt tcttattatt gacactaata
    48181 ttattggaaa atcttataaa atcctgattc ctaagtttat ctaagataaa gctttattct
    48241 ctcataagat tttcgttgtt atattagttt atcacacttc caatcacttg cataatatat
    48301 attatatatc aggctgataa aaattattta taggcaaaaa aatcacacga gctgtgtgat
    48361 tccattattt gttaaaatac tttttagttt cagcaataac gactggcgac aagaccaaga
    48421 gggcaatcaa gtttggcaga gccatcaagg cgttaacgat atctgcgata atccagacca
    48481 tatccaactc gataaatcct cctaacaaga ccatgagcac aaaaaacaca cggtagagcc
    48541 agataaagcg agccccaaag aggaactcaa aacagcgttc tccgtaatag ttccaaccta
    48601 gaatcgttgt aaaggcaaaa agtacaagga agatggtcaa gagggcaggc ccaaagtgtg
    48661 aaaagactgt tgagaaagct gactgagtca aggcaacccc attcaagtca ccactccaaa
    48721 ctccagttac caagatggtc aaaccagtta gagtacaaat gatgagggta tcaataaagg
    48781 ttcctgtcat ggaaatcaaa ccttgctcta ctggttcatt tgtcttggca gctgcaatag
    48841 gagcagaacc cagaccagat tcgtttgaga acacaccacg cgccacacca ttttgaatag
    48901 ccatccgaac gctagcacca gcaaatccac ctaccgcagc aaggggacta aaagctgagg
    48961 taaagactaa agcgattgtg ccagggattt ttccgatatt aaagaaaata actgtaagag
    49021 ttcctaagat ataaatgagg gccataaaag gaacaacagt agttgaaacc ttagaaatag
    49081 acttgagtcc accaaagact gcaatcgcta caaagacaga caagacgaga gctgtgatgg
    49141 ctggcgaaat cgtcgttgta ttttggatag attctgtaat cgagttgact tgggtgaagg
    49201 ttccgattcc caagagagca accaatactc ctgctactgc aaacaaaaca gcaagtggtc
    49261 gccacttttc tcccatccct agaaggatat agtgcatggg acctcccgct actgcaccat
    49321 ggtcgtcctt ggtgcggtat ttgatggcca agagtccttc cgcatacttg gtagccattc
    49381 caaagaaagc cgccatccac atccaaaata gagctcctgg tccaccaacc ttgatagccg
    49441 tcgcaactcc tatgatattt cctgttccaa cagttgatgc caaggctgta cacagagctg
    49501 caaaactgga tacatcacca tgtcccttat cctggataaa aataagctga aaggccttgg
    49561 gcagacgcaa aacctgcaag agtcctagcc gcatggttag gtaaatccct gttccgacca
    49621 ataaaatcaa gaggggcggt ccccaagcaa aagcatcgat tgatttaagc aattctaaca
    49681 tttccttctc ctatcgtttc aaccccaaaa gaaagagcac atgcaagata catgtactct
    49741 ggaatgctta gataaatgct aaaaagcggt ctatcctagc tctgtccttt tacctgagag
    49801 tttgagcagt tgcctgcctt gccccttcgg tgcctttacg gtctctccag agttccgtcc
    49861 atttacagtc atggaaaatc aaacgattcc ccacttctat taaacttcat tcggtgttgg
    49921 tatttaattg attctaattt tacaaaaaat gttggctttt gtcaatgtgt ttattagtaa
    49981 aaattagttc aacagttttt actttataaa gtccagaata ctgctatcct ttaaaagtga
    50041 caatagtcgc accactgcct ccagcatttt gtggggcata gccgaaactc ttgacatgtt
    50101 tgtttctttg caagtatttg gtaactcctt cacggatgac tcctgttccg ataccatgga
    50161 tgatatcaac ttgagccata ttgttaagca aggcttggtc gatgaaggta tctagctcat
    50221 tcatggcttc ttcatagcgc ttgcctcgaa gatccagtct agcttgaggt cctcgcccag
    50281 aagttcgttt cacaacattg acctgtttct tcttgactgg tttttcttgc tgggcttgaa
    50341 caagatcaaa ctctttctct tccaaggtca tcttaatcaa gccaacttgg gcttcccagc
    50401 gaccgtcctt gagttgactg gtcaaggtac cacgctgacc ataactgaga accacgatat
    50461 catctcccac ctttggagct cgttttttct tggccttttg aaggacctta tttttagaca
    50521 agtccacttt ttcaggagcc aattttttca acttgacctt ggcttcaatg atttcgtggg
    50581 gcttgagttg ggatttactg tggagatttt tgagaatctg gtcactttca cttaaggcca
    50641 tatccacaat ctcagcagcc tgttcacgcg ccttgttaag ctcggtttcc ttttcacgat
    50701 taagctcgtt gtagagtttt tttagcgcac ggttcatctt gagattttct tgctccacct
    50761 cacggatatt gtccaaacgt ttgcggcttt ccagcgtctg ctcttctaat tgctcaatga
    50821 tacgattgac gtcattgtcc tgatcgatct gctgactggc atctcctacg ataacttcag
    50881 ataggcctag acgtttggca atttcaaagg cattacttcg gccaggaaca ccctgcataa
    50941 agcgataggt cgggcgaaga gttgcagtat caaactccat actggcattt tgcacaaagg
    51001 ctgtctcaat accgtaggcc ttgagttctg gatagtgggt cgtcgccatg gtcttgattt
    51061 gacgcaggcg aaggtcctcc agaatagcca tggcaagggc tgctccctct tggggatcag
    51121 taccagcccc caactcatcc aaaagtaaga gtgaatgttg gttgaccttg ccaagaatat
    51181 ccacgatatt ggtcatatgg ctagagaagg tagacaagct ctgctcaata gactgctcat
    51241 ctccaatatc agcaaagatt tcttcaaaaa taccaacacg acttcccttg tctgctaaaa
    51301 tcggcaatcc tgactgggcc atgacctgtg tcaagcccag agttttgagc atgatggtct
    51361 tcccacctgt attgggacct gtaatgacaa tagctgttaa atcttgacca aaatagacat
    51421 catttgcgac ggcatttttg accaaaggat ggcagacatg gagcagttga atctcttgat
    51481 tttctgacag ctgaggcacg actgcttgtc tttcttggat aaatcgaacc ttggcacgaa
    51541 tcaagtccag atgaccgata atccaagcgt cattagcaat ctcagccgca tgagggcgga
    51601 cacgctcaga aatttcttgg agaatgcgaa gcatttcata gcgctcatct gctcgcagac
    51661 tagcaatttc ttcgctcagt ttgactacct cacgtggttc gatatagacg gtgtttccac
    51721 tagcagaaat atcatgaacg acacctgcaa tcttattgcg gtaggtgttt ttgactggta
    51781 aaacctgacg gccatttctg ctagcaacaa ttccttccgt caacatctgc gctttttgct
    51841 tgagcaagtc ttgtaaaaca tcgcgtacct gactctcgct atcatgtatt tttcgacgga
    51901 ttcgcgccaa ttcttcactg gcaaaatttt caatgaaacc cgcatcatta aaggcctgaa
    51961 gatttccttg taattgcgga aaatcatgta atttctcaaa ccaaagggct aattcttcca
    52021 agctgacatt ttccagattg gcgtaaaaac tttgaagttc tcggctggta agaagcacgc
    52081 gtttcaagag taggaactcc tcgatattga gatccgctcc catctccaac ctcttgcaga
    52141 ctcctgcaat ttccttagtt gagagaatag taaaatgcgg ttgctcgacg aaaagagcct
    52201 gcatttcttt catctcagca aaagcctgtt tgattttatc tgctttggca gtcggagcca
    52261 gctgtctcaa ttgctccaag ccctgctcgg tcaacaaatg aggctcaaac aaggccttga
    52321 ccttatcgag ctctaatgtt tctaatattt tcttattcat ctttatttcc ttgtctttga
    52381 atgtctaggt gtggtagctt tttacattct gatagattcg agtcaaatct gtaaacaaag
    52441 ggctaggaaa actcctgccc tttttatccg attaaatttg tcacccagat ttgtttgagc
    52501 caactggttg ttatcggtat actctggatg atgtgttttg cgacgatact cttttcaaga
    52561 ggattttgta taactgccat ggggatggtc gccaagattg tcaaggccat ttgcaagaca
    52621 aataaggtca ccaacatgga caagatacct gctgaaactt ggaacaactt accacccagt
    52681 tttttgctag gaatcaagtg taagagaaga ccaagcaaac gaccaatgct atagacaatc
    52741 ccaaatacaa gcaagtagcc gatacctgca taaaagacct tatccagctg aaagagttga
    52801 tccgatggga aaaagaaagt cccctgacct tcctgcgaat ttgcataagg gagcaataaa
    52861 tggaattgct ctccaagccc cttataaaac tggccagcca taaaagccga tgccatggct
    52921 gaaatcaggt aataaacctg taagagcagg cctctccgat agccgatata aaatccccaa
    52981 accaagacca atagaagaag gaatgaaatc ataaggaatc ctcaatcttg ctctgttctt
    53041 gcttacaagt cacaagcttg tgacggagtt cttctagctc ttgctcctta tcgtcaaatt
    53101 caatctcacg gctgagctga gttgataaac agttgactgc caacaaaaga gcgattgttt
    53161 catcatctgc gctaggcatt tgttctttaa ttgcttggta tttttctgtc gcaaccttag
    53221 cgatttcctc cataaaaagg ttatcatgtt cgcttgtcaa ggttaacgat tttttcccga
    53281 atgtaaattt gaatcgattt agatttgcca taaaattcac ctcacgatat tataccaaaa
    53341 ttcgctaatt ttgtcagttt ttacaaattt tactgctttt gtggtacaat agaaactatg
    53401 gcaagtatca cactcacacc aagcgaaaag gatattcagg cttttcttga acactatcaa
    53461 accagtctgg ctcctagcaa gaatccctat atccgctact ttttgaaact acctcaagca
    53521 acggtttcta tctatacttc tggaaaaatc ttgcttcagg gtgaaggggc tgaaaaatac
    53581 gccagtttct ttggctatca agctgtagag caaaccagcg gacaaaatct tcctttaatt
    53641 gggacagatg aggtgggaaa tggttcctac tttggtgggc ttgcagttgt ggctgccttt
    53701 gtcacacctg accagcacga ctttttacga aaactcggtg tgggggattc taagactctg
    53761 accgaccaaa agatccgtca gattgctcct attctcaagg aaaaaatcca gcaccaggca
    53821 ctccttctct cacccagcaa gtacaacgag gtcatcggag accgctacaa tgctgtttcg
    53881 gttaaggttg ccctccataa tcaggctatc tatctcctcc ttcaaaaagg tgttcagcct
    53941 gagaaaattg tgattgatgc ctttaccagt gctaaaaatt atgacaagta cttggcacaa
    54001 gaggccaatc gtttcagcaa tcctatcagc ttagaagaaa aggctgaggg caaatacttg
    54061 gctgtcgcag tttcttctgt cattgcgcgt gatctctttc tggaaaatct tgaaaatttg
    54121 ggacgagaac tgggttatca gcttccaagt ggagctggaa cggcttctga caaggtggct
    54181 agccagattt tgcaagccta tggtatgcag ggactcaact tctgcgccaa attgcacttt
    54241 aaaaacactg aaaaagcgaa aaaacgctta gaaaggtaag ttatgaattc acttaaaaat
    54301 ttcttaaaag agtggggatt gttcctccta attctgtcat tactagcttt aagtcgtatc
    54361 tttttttgga gcaatgttcg cgtagaagga cattccatgg atccgaccct agcggatggc
    54421 gaaattctct tcgttgttaa gctcctccct attgaccgtt ttgatatcgt ggtggcccat
    54481 gaggaagatg gcaataagga cattgtcaaa cgtgtcatcg gaatgcctgg cgataccatt
    54541 cgttacgaaa atgataaact ttacatcaat gacaaagaaa cggacgagcc ttatctagca
    54601 gactatatca aacgcttcaa ggatgacaaa ctccaaagca cttactcagg caagggcttt
    54661 gaaggaaata aaggaacttt ctttagaagt atcgctcaaa aagcccaagc cttcacagtt
    54721 gatgtcaact acaacaccaa ctttagcttt actgttccag aaggagaata ccttctcctc
    54781 ggagatgacc gcttggtttc gagcgacagc cgccacgtag gtaccttcaa agcaaaagat
    54841 atcacagggg aagctaaatt ccgcttctgg ccaatcaccc gtatcggaac attttaagag
    54901 acctaagagg ccgagaatca caaatctcag cctcttcttc tatcgtgaga agtgattgtt
    54961 tattgacaaa tactcaatga aaatcaaaga acaaactagg aagctagccg taggctgctt
    55021 aaaacagtgg tttgaggttg tggatagaac tgacgaagtc agctcaaaat actgttttga
    55081 ggttgcagat ggaagctgac gtggtttgaa gatattttcg aagagtataa aataaaaaca
    55141 atcccaactc tcacctattc atgcaaagga attttatgga agtttatttt tcaggaacca
    55201 ttgaacggat tatttttgaa aatcccagca atttttatcg catcctcctc ctagaaatcg
    55261 acgatacgga cgcagaggat tttgatgatt ttgaaatcat tgtcacagga accatggctg
    55321 atgtaattga gggcgaagac tatacttttt gggggcaaat tgtccagcac tccaagtatg
    55381 gagaacaact gcaaatcagt cgttatgatc gcgcaaaacc aactagtaag ggattggtca
    55441 agtacttttc aagtagccat ttcaagggga ttggtctcaa gacagctcag aaaatcgtag
    55501 atacctatgg cgaaaatacc attgatgaaa ttttgcaaca cccagaaaag ttagaaggca
    55561 tcgcaggact ctctgccaaa aatcgcgagg ctttcgtctc cactctccgt ctcaactacg
    55621 gaacggagat ggttttggcc aaactagcca actacggcat tcccaacaaa ctagcctttc
    55681 agattcaaga cttttacaag gaagaaaccc ttgatgtggt tgaaaattat ccctaccagc
    55741 tggttgagga tatcaagggt ttgggcttta caattgctga ccaactagct gaggaactag
    55801 gcatcgaaag tcaggctcct gaacgcttcc gcgccggtct agttcacagt ctttttcagg
    55861 cctgtatgga aacaggagac acctatgttg aagcacggga tttgctggaa caaaccctta
    55921 ctctccttga gtcttcccgt cccgtagaac tagaccccag ccaagttgcc caagagctct
    55981 cctacctgat cgaagaagac aaggttcagc agattgatac caagatcttt gacaacagcc
    56041 tctttttcgc tgaggaaggt atccgcagtc acttgattcg tatccttgaa aaaggagaac
    56101 agaagagaca agatttagaa actattcaaa agcatatcac tactgtcgag caagaactgg
    56161 ggattgagta tgataacatt caaaaacaag ctatttgtga cgctatccag aacaaggtct
    56221 ttatcctgac aggtgggcct ggtactggta agacaactgt tatcaatgga atcatcgctg
    56281 tttatgccct tttagaagga cttgacttca ggaagaaaag caatctgccc attcttcttg
    56341 ctgctccaac tggtcgagct gctcgtcgca tgaatgaatt gacaggtttg cctagcgcga
    56401 ccatacatcg ccacttggga atgacaggtg acgatgatac cagtcatctg gaagattacc
    56461 tagatgctga ctttatcatc gtggatgaat tctctatggt agatacttgg ctgaccaatc
    56521 aactcttctc caatatctct tctaacagta agatcctcat cgtaggtgac agtgatcagc
    56581 taccttctgt cagtcctgga caggttctag cggatctgct tcatattcct ttgattcctc
    56641 agactcgctt ggaaaaaatt tatcgacaaa gcaaagaatc aaccatcgtc accctagcta
    56701 gtcagattcg acagggcatc ttgccagctg atttcaccca aaaaaaagct gaccgttcct
    56761 actttgaaat tgctagtggc catattcctg ccaccattga aaaaatctta ggtgtcgccc
    56821 tcagaaatgg tattcctgcc cgtgatatcc aagttctggc tcctatgtac cgagggacgg
    56881 cagggattga tgctatcaat cagctcatgc aagacctgct caatccccca caaaaagatc
    56941 aactcagttt tgaagctcct cagtgccact atcgtaagag agacaaggtc attcatttgg
    57001 ttaacgatgc tgaaatcaat gtctttaatg gggatttagg agctatcaca gacctgattc
    57061 ctggtaaata caccgaatcg aaacaagacg agattgtcat tgattttgat ggtaatgaag
    57121 tctcttaccc ccgtaacgaa tggtacaaga ttcgcttggc ctatgccatg agtattcata
    57181 agtctcaggg aagtgagttc ccagttgtca tcctaccgat tactagtgct agccgacgta
    57241 tgctggagcg aaatctcatc tacacagcca ttacacgtgc caaaagcaaa ctcatcttac
    57301 taggcgaatt acaagccttc gactatgcta cccaacacat cggaactgcc cgaaaaacct
    57361 atctgattga acgcttcagt gatctactgg agaatgttga agaaaagcaa caagctgtct
    57421 ctgaaacagt cacatcaagt gcctctgaac aatcctacat cctaaccgaa gaaaactggg
    57481 acagcattcc agccatgatt gggattacag acacagacct caaagagatt tttggaaaat
    57541 agtacatcag aaaacccacc aattcaggtg ggttttctgt ttattaagat tattttactg
    57601 ttgctgtgct tgtgatcaat tcaacagctt ttttgatagt gatatcatgt ttcaacatgt
    57661 cagctgaaag caagttttga acttgtgcaa cttccatgtt gtagtctgct gccaattgct
    57721 caacttcttt ttggatttct tcttctgaag catcaaatcc ttcagctttg gcaactgctt
    57781 cgataacaag gttagtctta gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt
    57841 cttcttgagt agttccagtg atttggaagt acatgtcagg gttgatccct tgacgttgca
    57901 agttcccaag gaattcattt actgaacggt gaacttcttc atggatcatt tcttctggaa
    57961 gttctacgat ttcagcgttt tctacagctg tatcaattgc tgcaccttca actgcatctt
    58021 tgtaagcttc ttctttagca gcagccaatt ctttgcggta tttttctttc aagtcagcaa
    58081 gtgtttcaac ttcttcatca atgtcttttg caagttcatc gtcaagagct ggaacttctt
    58141 tagcttttac ttcgtggata gttgtcacga atttagcttc tttacctgca aggtcttctg
    58201 cttggtagtc ttctgggaat gttacgataa catcaacggt ttcgccagct gagtgaccta
    58261 ccaattggtc ttcgaaacca gggatgaatt gacctgaacc aagtccaagt gagaagtttt
    58321 caccttttcc accgtcaaat tcaacaccgt cgatagaacc aacgaagtcg atcacaacag
    58381 tgtcgccgtt ttcagcagca gcttccttga taaccaattc agccagattg ttgcgttcgc
    58441 gttcgatacg ctcttcaaca tcagcgtcag ttacttcttt ttctacatca actgatactt
    58501 caaggttttt gtagtcaccc aattttactt caggttttgt aacgacttca gcagcgataa
    58561 cccagtcttg acctttttcc attgaagtta cgtcaatttt tggttgggca accacttcaa
    58621 gaccagcttc ttttacagct gcttcataag cgtttggcaa aagagcgttc ataacgtctt
    58681 ggtaaagtga ttcttcacca aattttttgt cgaagatagg acgtggaagg tgacctttac
    58741 ggaaacctgg aacattaaga gatttcttca ctgacttgaa gacacggtcc aattctggtt
    58801 tgatttggtc ttgagagata gtgaaagtca agacaccacg gtttgtttct ttgttttcaa
    58861 atgatacaga cattctgtca tttctcctta aaatttttta aatacagtct attataacat
    58921 tttctataaa taaaatctag actaatgcag ccaattatag acaacaagcc tttttcctaa
    58981 ctaaaacact cataaagtat agacaatttt agactacttt ggatatcttt tggttagtca
    59041 ttttccaaaa ctaatttatc taatttttca gttatatagt agattgaaac tagaatagta
    59101 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttgtcctg
    59161 ttcttgtttc attttactat atagatcgca ttcgaaagaa ttcgttccaa aattgcttgg
    59221 ttcgttcttc tcttggacga ctaaagaatt gatgggcatt atttttttca acaattttcc
    59281 caccgtccat aaaaataaca tgatgggcta catctctagc aaaacctatc tcataaagct
    59341 gatcaaaaac tcaatctgag gagaaaatcc aataaggctt tccataataa aggacatcct
    59401 atcaagattt ttgaacaccc gataggctgc ctttttccga ttttgaagac tttttgtcca
    59461 gcttctttta ccttataaat aacaacaaaa atcaaagaca agctagaaag attaccgcag
    59521 ataactcaaa cagtgttttg aggttgcaga caagactgac ggagtcagct caaagcactg
    59581 ctttgaggtt gtagatagaa caacatatgc ctaagacaaa gcgatgctaa cctgatttga
    59641 agagattttc gaaaaagatt aaatatactc tacaatttgc tcaatcaatt cttggtcgtc
    59701 taaacctgta acttgtataa caacatcttt gactgattgt ttagccaaca attcacctaa
    59761 tcgaatactt tcttcatcat ttacatcgcg atagtcaaag gcatagccaa ctgttttaag
    59821 taggttttta tatgacaaac tgagttcttt caattcacgt atcggccgga tgaatcgttc
    59881 attatagcct aattttcgga ttggagtacg agctacgcga ctaacctcgt ccactatgaa
    59941 agggttttca aaccgttcta taatgacttt gtgataattc tccaattctt ttttatcaaa
    60001 gttccatttg gcaatcaaga gactccgaat ttcagctaat acagattcaa tccgagattt
    60061 aatattagga ttttgaagag cttccaaaat tgtcttggca ccataatgcg caccaatgta
    60121 agctgaagtt gcatgtccag aattgactga aaaaagtttt cgctcaataa agggttctaa
    60181 atcttcttca taatgcacat cttttagacg taaatctgga tttttaagac gcttggtttc
    60241 cacgacccat tcattaaagg gctcgaccac aacaaaaagg gaatcttcgt gactttgtgc
    60301 tggaacaatc ctgtctactg cagcatttgg aaaacctatg tagttatcag caaatgtcaa
    60361 accttccgga cttaaatatt tcttgacttc ttgataaaga aattgagacc cgccaatcat
    60421 attttcacag gccataacat ccaatgcctg tgtatttcct gcaactcggc gagcttcgat
    60481 tcctttggct agaagttcgg cgataaaagg gagtatatta ggtccgattg cagtagtaat
    60541 aatatccgtc ttttgaatcg cttcaatgac ttgctcagga tgttctttgc tattaatgcc
    60601 agccacatta gttacttcta tacgagactg tcctttctgt gcaatttcaa tttcatactt
    60661 gcccttttca tttagagcat gaattatctg attattgaca tccacaaaat caatatggaa
    60721 accattttta aatagaattt cacctataaa accacgaccg atattaccgg caccaaaatg
    60781 aacagaatgt ttcattcaat ttctcctttt cctatttgag ggacatatat actagatgac
    60841 aaatgacgaa attcaattat tcaacagcat caaataagcg caatacttcc tcttttgact
    60901 gagcatctgc tagtttaaga acattatcta catctgcaca gaagatagaa attttctgaa
    60961 taatttctaa gtgttcatta ccaataccag caataccaaa aagaaccgtt gccacttgag
    61021 ggttagatac attcccaaaa tcaacccctc tagggacttg aacgactgta ataccagact
    61081 tgagtacatc cttttttgct gcatctgttc catgcggtat ggcgataaag ttacccatgt
    61141 aaacagatag ctctttatct cgctcaatca tggcttcaat atagtcttca ttaacatatc
    61201 caccctcata aagaacttgc ccacaataac aaatagcttc ctccttgtta gaaaattgtt
    61261 tattaagctt aatcaaatgt ttttcaagtt tcatattagt tctccaattt cttaattttt
    61321 tcgttaaaaa tagtatttag catctgataa ataatggatt gatttcccgt cttgtaaatc
    61381 tctgtataaa gatgattttc aataatcgac tgactaatag ctgtcattaa atctctcgct
    61441 tcctcgctag cttctttaga cattagcatt agcagacacc ttttgacctc ttcttcctct
    61501 cgtttcattg acaatgcgga gataggtagt ttgagttcaa acatagtaaa actatttgtt
    61561 gttactttgc tagactgact atgtaaaagc accagaccag tattaggaat agccatagga
    61621 ctattctgga agtgagataa caattttctt gttaggtaat ctctgtcact cacattcttc
    61681 tgatattgga tgatttgttc taccgtgtgc tcaaatgatt gattattctc caattgaatc
    61741 aactcaaatt gactcaaaag ctgactacta gatattaaat aatcttgcaa gtcataactt
    61801 ttctctggag cgatagcatc acgcgcgaca attgtacgat gtgcctgtac atactgaagt
    61861 cgttcctgta attcaagcaa ttctttgacg gttggaaaac tagaaattac atcgatttcc
    61921 tgattagtca gcggcttggt agataaaata taatcatact gactgagatc aatactgtgg
    61981 taatctacta gagactgaat atctatcaac tctacaaaag gagcaacact cttaatttta
    62041 ctgactaata aatctctagt gacccgacgt tcatccgtta aaagcaaaac acggactgga
    62101 taaatctctg gactacggcc taagctagag ataaaatgta gggcaatcat gccatactca
    62161 tactctgtat gaagatattt cggaaaaata tcattcacta aaagactgat gactgtataa
    62221 agaaatttat tcctttcaac taaaatctgg atagattctg gcaaattttc accctgaaaa
    62281 aggataggga cgcctaaact gagccgaata tgatggaaaa gaaaattgaa taaaaccttg
    62341 tccttaaaaa agtcaatctt ggtatacatg gaaaccgtat caatcagatt tgaaatattg
    62401 tagaaaaatt caccatcaaa tttctccgta aagagcggat tgtcctgacg tttaatgatt
    62461 aattcatcca agatgctcgc aaaatagata atttcctgaa tactataaaa ttgtgcagtc
    62521 tgcttagagt aagcttgaaa aattttttga gaaatttcca aagcctgctt actagtatta
    62581 ggtgaatttt caatgttttg ctcctgacct ataagagata acaagatcgc aaaaaacatc
    62641 ttcatcctag catccatatc tggaaaacct gacagttgct tattaacaat ctgactggcc
    62701 agcctagttc tatctgcttc taaaatatca aagctcccaa aattaccggt tgaaaaatct
    62761 gctactgaga tacagtttgt cagtaaaata gccaaaaatc ttctcttacc aactgaatca
    62821 ccagaaatcc gataaccttt ttgtcgttca attttcagat caaagtctaa aagacgctta
    62881 tcaatatctg aaatatcctg aataatagtt acattactga ctttcgtgca ctcttgcaat
    62941 gcttcattgg tgacaaaacc gctctcagtc agaaggcgat aggtaatcaa ctcttgtctt
    63001 tcttggggac tatactcaac taacacttca agttctgtcg gcaaatcatc caactctcca
    63061 gtcaaaatat agtatttccc atgcttcgtt atttcgattc catattgctc catgctatct
    63121 gtcaaatctg ataaagttcg ataaattgtt ctagatgaaa cctgtaagat ttcagtcata
    63181 tcttgcattg aaagcttccc tacatgtagg aaagccttca ataattgttc ttctcgtttg
    63241 gttaatagca ttcgtaattt agaaacctct agttctattt gtacattcta gcagccattt
    63301 tgtcatattc tggtgttgtt actaaactat ccacaataag aaattgagaa ttcggtgctg
    63361 cttgctgcac ttctgcctgt aaagaaatag ttgttacaat cattatgttt ttagaattaa
    63421 attcacctaa ttctgaaatt ttggcagtag aaactggaat acgaatattc ttgtttctaa
    63481 agatagcccg aatcgtttca cagcccatag ttgcagttcc ctgtgcttta ccataagcaa
    63541 ctactacagc atcaatatgg ttaaggtcaa tttcctgact atctactggt gctgaagttg
    63601 gtatatctcc ttcaatttct gctattggaa aagctcctgt taatgaagct acaatttcat
    63661 cataacgagg ggacgctaag aaattatcaa cagaaacatg aatagcactt ggactcttgt
    63721 ctttagctct tggtgtcagt tcttcctgag taacaattaa tgtttttggt gtatcaagca
    63781 aatttgagat tgcctgatta gatactggaa tctctagacc tgctttttta accttatctc
    63841 gaagaatact agctcccata gcagagcttc ccataccagc atcgcaggcg aaaatgattt
    63901 tttccactga gtctgtcgaa acaactgcat caacagaagt tgatactaac tgacctttag
    63961 actgagcctt agctgcttgg gtagccgcct gagcagcttc gagcgaatcc tcagttgact
    64021 tgtctgcatg aagaataagg gctgctacaa ggaaagaaac aactgctgcc actaaaacac
    64081 ctaaaagaac atttagatga ggccaaacac cttttggcgc cgtagccata atcgcaataa
    64141 tagaacctgg tgaagctgga gatttaagac cagcgtctaa gagttgaaaa gtaaaagttc
    64201 cagagatacc tcctgccata gcagctaaaa atagagtagg cttcatcata acataaggaa
    64261 agtaaatttc atgaatccct ccgaagaaat gaataaccat tgccccccaa gaagaagatt
    64321 tagcagaacc tttaccgaat acagcataag ctaatagaat tcccaggcct ggtccaggat
    64381 tagcttccaa taggaagaga attgacttac cagcttgagc tacctgttct actcccagag
    64441 gagtaaaaat gccatgattg agggcattat tgagaaaaag gactttagcc ggttcgatga
    64501 taatattagc cataggaagg aggcgagcat tgacaatagc ctcaacacca ttcccaacag
    64561 ctacagtaag agtcgatacg actggaccga ttgcgtagaa agccaaaagc aataatgcaa
    64621 aaccaacgag accagctgag aagttattaa ctaacatttc aaatccggga cgaatttttt
    64681 cctggaactt ctcatcaaat ttcttgatag tccatcctcc cagtgggccc attaccatag
    64741 ctccgataaa cataggaaca ctagaacctg tgattgcacc aacagtagca atagctccta
    64801 caacggcacc acgttggcca tggatcatat atccacctgt gtaaccaatc aggattggca
    64861 ataaatacgt taacatagga ccaacaacag tagctaactg ttcatttggc agatagccat
    64921 cagcgataaa gagggcagtc aatactcccc aagcaataaa tgctccaata ttgggcataa
    64981 ccatatttga aagcgatgtc cctagttttt gaaccctgac cttcaatgat actttttctt
    65041 ccattagatc atcctccttt tcttaaaact agtatataca aagttaaaaa cctttaaaac
    65101 taaagttttg tcacagattt tgtgtcaaaa cattactttt gacgaggctg ggcaaaaagg
    65161 cttaaaaatt ataaaacgca tcatatcagg tgtacatgaa ctacacccca aaagttagac
    65221 agaaaaaatc taacttttgg ggtgttttta ttatgaaatt aacttatgat gataaagttc
    65281 agatctatga acttagaaag caaggatata gcttagagaa gctttcaaat aaatttggga
    65341 taaataattc taatcttagg tacatgatta aattgattga tcgttacgga atagagttcg
    65401 tcaaaaaagg gaaaaatcgt tactattctc ctgatttaaa acaagaaatg att
//
LOCUS       DAVIME010000006        52178 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVIME010000006 DAVIME010000000
VERSION     DAVIME010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52178
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.006"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(136..1497)
                     /gene="dnaA"
                     /locus_tag="VV588_000411"
     CDS             complement(136..1497)
                     /gene="dnaA"
                     /locus_tag="VV588_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU7082810.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1710..2468)
                     /locus_tag="VV588_000412"
     CDS             complement(1710..2468)
                     /locus_tag="VV588_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU7082811.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2526..3707)
                     /locus_tag="VV588_000413"
     CDS             complement(2526..3707)
                     /locus_tag="VV588_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU7082812.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3890..4369
                     /gene="rlmH"
                     /locus_tag="VV588_000414"
     CDS             3890..4369
                     /gene="rlmH"
                     /locus_tag="VV588_000414"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU7082813.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEELSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4413..4486
                     /locus_tag="VV588_000415"
     tRNA            4413..4486
                     /locus_tag="VV588_000415"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4447..4449,aa:Arg,seq:tct)
     gene            4652..4777
                     /gene="comC"
                     /locus_tag="VV588_000416"
     CDS             4652..4777
                     /gene="comC"
                     /locus_tag="VV588_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU7082814.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            4798..6123
                     /locus_tag="VV588_000417"
     CDS             4798..6123
                     /locus_tag="VV588_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU7082815.1"
                     /translation="MDLFGFGTVIVHFLIISHNYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFS
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6120..6872
                     /locus_tag="VV588_000418"
     CDS             6120..6872
                     /locus_tag="VV588_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7082816.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6924..6995
                     /locus_tag="VV588_000419"
     tRNA            6924..6995
                     /locus_tag="VV588_000419"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6957..6959,aa:Glu,seq:ttc)
     gene            7001..7074
                     /locus_tag="VV588_000420"
     tRNA            7001..7074
                     /locus_tag="VV588_000420"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7035..7037,aa:Asn,seq:gtt)
     gene            complement(7115..7657)
                     /locus_tag="VV588_000421"
     CDS             complement(7115..7657)
                     /locus_tag="VV588_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU7082817.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7835..8602
                     /locus_tag="VV588_000422"
     CDS             7835..8602
                     /locus_tag="VV588_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU7082818.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLSVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSKKTTTLSNI
                     QSTAAYQSLTSEQQTGISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGAVTSKLVPASQLIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            8687..9094
                     /locus_tag="VV588_000423"
     CDS             8687..9094
                     /locus_tag="VV588_000423"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082819.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNIIFAKLPSGRH
                     PESRWPWLKSRAEINGIIAVLAGILVYGGVLLV"
     gene            complement(9464..12016)
                     /locus_tag="VV588_000424"
     CDS             complement(9464..12016)
                     /locus_tag="VV588_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU7082820.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQALKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISITSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTYKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12078..13700)
                     /locus_tag="VV588_000425"
     CDS             complement(12078..13700)
                     /locus_tag="VV588_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU7082821.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13906..14931
                     /gene="trpS"
                     /locus_tag="VV588_000426"
     CDS             13906..14931
                     /gene="trpS"
                     /locus_tag="VV588_000426"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU7082822.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            15083..16561
                     /gene="guaB"
                     /locus_tag="VV588_000427"
     CDS             15083..16561
                     /gene="guaB"
                     /locus_tag="VV588_000427"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU7082823.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSINEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16612..17709)
                     /gene="recF"
                     /locus_tag="VV588_000428"
     CDS             complement(16612..17709)
                     /gene="recF"
                     /locus_tag="VV588_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU7082824.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(17712..18080)
                     /gene="yaaA"
                     /locus_tag="VV588_000429"
     CDS             complement(17712..18080)
                     /gene="yaaA"
                     /locus_tag="VV588_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU7082825.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18239..19489
                     /locus_tag="VV588_000430"
     CDS             18239..19489
                     /locus_tag="VV588_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU7082826.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            19486..20769
                     /locus_tag="VV588_000431"
     CDS             19486..20769
                     /locus_tag="VV588_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU7082827.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSNRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20811..21632
                     /locus_tag="VV588_000432"
     CDS             20811..21632
                     /locus_tag="VV588_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU7082828.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21643..22188
                     /gene="pgsA"
                     /locus_tag="VV588_000433"
     CDS             21643..22188
                     /gene="pgsA"
                     /locus_tag="VV588_000433"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU7082829.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22185..23012
                     /locus_tag="VV588_000434"
     CDS             22185..23012
                     /locus_tag="VV588_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU7082830.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            22997..23836
                     /locus_tag="VV588_000435"
     CDS             22997..23836
                     /locus_tag="VV588_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU7082831.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23829..24623
                     /locus_tag="VV588_000436"
     CDS             23829..24623
                     /locus_tag="VV588_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU7082832.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24682..25500
                     /gene="mreC"
                     /locus_tag="VV588_000437"
     CDS             24682..25500
                     /gene="mreC"
                     /locus_tag="VV588_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU7082833.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25500..25994
                     /gene="mreD"
                     /locus_tag="VV588_000438"
     CDS             25500..25994
                     /gene="mreD"
                     /locus_tag="VV588_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU7082834.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26088..27266
                     /locus_tag="VV588_000439"
     CDS             26088..27266
                     /locus_tag="VV588_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU7082835.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27490..28269
                     /gene="rpsB"
                     /locus_tag="VV588_000440"
     CDS             27490..28269
                     /gene="rpsB"
                     /locus_tag="VV588_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU7082836.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGHQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            28348..29388
                     /locus_tag="VV588_000441"
     CDS             28348..29388
                     /locus_tag="VV588_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU7082837.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEDGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            29634..29957
                     /gene="tnpB"
                     /locus_tag="VV588_000442"
                     /pseudo
     CDS             29634..29957
                     /gene="tnpB"
                     /locus_tag="VV588_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(30098..30385)
                     /locus_tag="VV588_000443"
                     /pseudo
     CDS             complement(30098..30385)
                     /locus_tag="VV588_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30376..30774
                     /locus_tag="VV588_000444"
     CDS             30376..30774
                     /locus_tag="VV588_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU7082838.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(30971..31891)
                     /gene="cysK"
                     /locus_tag="VV588_000445"
     CDS             complement(30971..31891)
                     /gene="cysK"
                     /locus_tag="VV588_000445"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU7082839.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(32176..32811)
                     /locus_tag="VV588_000446"
     CDS             complement(32176..32811)
                     /locus_tag="VV588_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU7082840.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            32867..34165
                     /locus_tag="VV588_000447"
     CDS             32867..34165
                     /locus_tag="VV588_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU7082841.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            34162..34824
                     /locus_tag="VV588_000448"
     CDS             34162..34824
                     /locus_tag="VV588_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU7082842.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            34904..35452
                     /gene="raiA"
                     /locus_tag="VV588_000449"
     CDS             34904..35452
                     /gene="raiA"
                     /locus_tag="VV588_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU7082843.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            35588..37561
                     /locus_tag="VV588_000450"
     CDS             35588..37561
                     /locus_tag="VV588_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU7082844.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQIIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            37558..38010
                     /gene="rplI"
                     /locus_tag="VV588_000451"
     CDS             37558..38010
                     /gene="rplI"
                     /locus_tag="VV588_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU7082845.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            38053..39405
                     /gene="dnaB"
                     /locus_tag="VV588_000452"
     CDS             38053..39405
                     /gene="dnaB"
                     /locus_tag="VV588_000452"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU7082846.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            39407..39673
                     /locus_tag="VV588_000453"
     CDS             39407..39673
                     /locus_tag="VV588_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082847.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            39762..41108
                     /gene="cbpD"
                     /locus_tag="VV588_000454"
     CDS             39762..41108
                     /gene="cbpD"
                     /locus_tag="VV588_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU7082848.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      41191..41293
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41364..41654
                     /locus_tag="VV588_000455"
     CDS             41364..41654
                     /locus_tag="VV588_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU7082849.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            41617..42375
                     /locus_tag="VV588_000456"
     CDS             41617..42375
                     /locus_tag="VV588_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7082850.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            42414..43421
                     /locus_tag="VV588_000457"
     CDS             42414..43421
                     /locus_tag="VV588_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU7082851.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            43421..44146
                     /locus_tag="VV588_000458"
     CDS             43421..44146
                     /locus_tag="VV588_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7082852.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLE"
     gene            44269..44727
                     /locus_tag="VV588_000459"
     CDS             44269..44727
                     /locus_tag="VV588_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU7082853.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            44729..47161
                     /locus_tag="VV588_000460"
     CDS             44729..47161
                     /locus_tag="VV588_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU7082854.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            47482..48135
                     /gene="rr06"
                     /locus_tag="VV588_000461"
     CDS             47482..48135
                     /gene="rr06"
                     /locus_tag="VV588_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU7082855.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDEITQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            48132..49463
                     /gene="hk06"
                     /locus_tag="VV588_000462"
     CDS             48132..49463
                     /gene="hk06"
                     /locus_tag="VV588_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU7082856.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIYE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            49546..50073
                     /locus_tag="VV588_000463"
     CDS             49546..50073
                     /locus_tag="VV588_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU7082857.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            50152..>52178
                     /locus_tag="VV588_000464"
     CDS             50152..>52178
                     /locus_tag="VV588_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEU7082858.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSKN
                     NLTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNVDFNKKLSRIKTKYLY
                     GLKEKSEAELTLKTKETKEELTAAFEQFKKDTLKSGKKVAEAEKKAKAQKEEDRRNYP
                     TNTYKTIELEIAEAEVGVAKAELELEFAQAQVQIPQDTEKINAAKSKVEAAKSNVKKL
                     EKIKSDIEKTYLYKLDNSTKETPKSRVRRNSPQVGDSRELKETIDKAKETLSTYMVTR
                     LTKLDPSVFWFADLLMDAKKVVEEYKTKLEDASDKKSVEDLRKEAEGKIESLIVTHQN
                     REKENQPAPQPGGQAGGSMVVPPVTQTPPSTSQSPGQKATEAEKKKLQDLIRQFQEAL
                     NKLDDETKTVPDGAKLTGEAGKAYNETRTYAKEVVDKSKKLLSQTAVTMDELAMQLTK
                     LNDAMSKLKEAKAKLVPEVKPQPENPEPKPQPEGEKPSVPDINQEKEKAKLAIATYMS
                     KILDDIKKHHLKKEKHHQIVALIKDLDKLKKQALSEIDNVNTKVEIENTVHKVFADMD
                     TVVTKFQKGLIQNTPQVPEAPKSPEVPKVPDTPKAPDTPQVPEAPKAPDTPQIPEAPA
                     PETPAPAPEAPKTGWKQENGMWYFYNTDGSMATGWLEYNGSWYYLNANGAMA"
BASE COUNT        16540 a         8483 c        10949 g        16206 t
ORIGIN      
        1 gtattagaaa gataatagta ataatagagt ctgtgaaatc tgtggaaaac agcctttaaa
       61 caagtcatat caagtttttt agcttgttta aaaaatgtgg ataaaaaaga taaaaaacta
      121 aaagttatcc acaaattatt tgattttctt tttgattgat tcaatttcta aacgtaaatt
      181 atcgtcttga tcaatcaaag attttatttt ggcatgggca tgaatgactg tggtatgatc
      241 ttttccccca aattccttcc caatttttgg aagactatta tctgttagtt ctctagataa
      301 atacatggct acttgacggg ccaaaacaat attttgaagg cgtctacttc ccttcatttc
      361 tttgatacta acaccataaa agttaccaac ttcagtttgg attttatcaa ttgggatgac
      421 gagcatttgg ctaacatctt gtttgcgggc tctaatggct tctgcagcaa tatcaatagt
      481 gatatccttg atttttttta ctctggcaat taaagtgatg tcgttgatgg ctccctcaag
      541 atctcgaaca tttgaatcaa attgcccagc taggtattct agagtatcac tttggaaatt
      601 gtagcctaaa tgttccgttt tactttgtaa aatggcaata cgtgtttcaa agtcaggggg
      661 tgtgatagtt tgtgtcaatc cccaactaaa acgcgtgaca agcctctcct cgagcccttc
      721 tagatgtttt ggactacgat cactcgttag gacaatctgt ttttgcttgt catgaagggc
      781 gttaaaggta ttgaaaaatt cttcctgagt tgcgactttt tttccgctga gtgactggat
      841 atcatcgatt aacaaaagat caagactacg ataggtcttt ttaaactttt ccatttcccc
      901 aagtcttagg tgatcaagaa agtcattaat aaagctttcg gcagggatat atttaacacg
      961 cgcattagga atatttttta gaatttcatt tccaatagcg tttaataagt gagtcttacc
     1021 aaggcctggt cctccataga taaaaagagg gttataggtc agagccaaat cttcagagac
     1081 agctaaagcg gctgatacag cccaaacatt tccatcccct tgaataaagt tatcaaaggt
     1141 atacttttct tttaatcccg tatctgaata aggaatagat actaactttg gactatagtc
     1201 ataaagagtt aaatttgtag cttcttcaac ttgtgagcta gtcgtatctt gaggtttggt
     1261 gaaaatatag tggggagtta tttcagcgtc ataaatttca aaaccagcta ctacaataat
     1321 atcttttagt tgtttttccc agaccatttc catttcagag cgaggtagaa atatagtggc
     1381 aacattttcc tctaccttga tgagttcagc ttgaatagca tagaaatcat acatggatcg
     1441 agtcagtctt tcttgtgcaa attctaatat acgattccaa aattgttttt ctttcaatcc
     1501 tttctcctcc tttactattt aaaagtttaa tactagagat attttaccat agatagcaag
     1561 aattttccac aagctgtgaa aaataatcca caatgttact aaactttatc cacaggttgg
     1621 ggataaaaga agaaattatt gatttattaa gctttttatc gaaaaacata gtggataacc
     1681 ttgtgagata aaaaaataaa agaacagcct tatttcaggc tgttgataat tctactatat
     1741 tcttcttgat ttgaaaaaga aataatgatt tttccactgt cttttttaga tagtttaatt
     1801 tctacatcta atccgagtag ttttcttaac tgtttttctt cattttgtat gaaataatta
     1861 gttttttgct gtttcttttg ttttttctct gtcagaagag cttctaactt ccttacagaa
     1921 atatcttctt ctataatccg ttgaaagaaa tagtcttgtt gttccttatt taacccaact
     1981 agggaacgcg catgggcttg tgatagtttg ccattttcta cttctgagag aatctgttct
     2041 ggcaaggaaa gtaaacgaat ggagttgctg atatatggac gagacttgcc catcttatct
     2101 gcaatttcag catgggtgaa tcctttctct acgagagatt cataggcgcg tgcttcttct
     2161 attgggttta aattttctct ctgtaaattt tcaataatgg actggaccat catctcttgg
     2221 tctgaaatct gtttaacaac agctgggata gaccgtagac cagctaaaag tgaagcccga
     2281 tagcgtctct ctcctgcaag gatttcataa ccaataacag gagattgacg aacaataatc
     2341 ggttgaatga ccccattttc tttgatagac tgtgctagtt catctagttt ttctctatca
     2401 aattcttttc ggggttgata gggatttttt tgtatatctg tgatagaaat catttcaaat
     2461 ttttccatga ttctacacta acacatcttt tctcttatgt aaagctttct ttacatagat
     2521 gtcaattaag attctaaatc acctgaactc ttgttaagtt tgatagaggt agtttcttct
     2581 ttcccgttac gatagtaggt tatcttaatg gtgtctccga tagaatggtt gtaaagagca
     2641 ctttgtaagt ctgttgatga agcaatctct ttgtcatcta cttttgtaat tacatcgtat
     2701 ttttcaaggt gaccattggc aggcatatta ctttgtaccg aacgaacaat tacaccagat
     2761 gtaacattac ttggaatatt gagtcttctg atgtcgcttg tactcacatt agataaatta
     2821 accatctgga ttcccaaagc tggacgcgtc acttttccgt ttttttctaa ctgttcaata
     2881 atattgatag catcatttgc aggaattgcg aaaccaagac cttctacaga tgttcctcca
     2941 tttgtagcaa ttttacttga ggtaattccg ataacctgcc cttgaatatt gatcagtggg
     3001 ccgccagagt tacctgggtt aatagcagta tcagtttgga tggcttttgt agaaatagct
     3061 tgtccatctt ccgattttaa ggatacattt ctattgagac tggatacgat accttgagtg
     3121 acagtatttg catattcaga acctaacggg ctaccgatgg caatagcagt ttctcctaca
     3181 gttaacttac tagaatcacc aaactcagct actgttgtca ctttttctga agagattttg
     3241 acgacagcaa tatcagagaa agtgtcagct ccgacaattt ctccaggtac tttagtccca
     3301 tctgacaatc gaatatctac tttgctggcg ccatttataa cgtgattgtt ggtgacgatg
     3361 taagcttctt tatcattctt tttataaata actccagatc cttcactaga gattcgctga
     3421 gaatctgtgt cagtatcatc attgccaaat acgctatttt gtctgtttgc cgaataagta
     3481 ataacagaaa caacagcatc ttttactttg ttaacagcct gtgttgttga attttcgttc
     3541 ttataggcag tttgtgtaat agtactattg ttgttagagt tgtttacact acttttttga
     3601 gttagttgag ttattgaaaa actacccaag gctccactaa aaaagctaat gacgataacg
     3661 actaataatt gaaaccattt tttgtaaaat gtttttagat gtttcatatt tgcctccata
     3721 tgtttgaatt actgaaagta taaactgact agcttaatta taacttaaac acaaaagttt
     3781 tacacaaact gtggataact cttttgaaac tgtgattttc ttaattgaaa tctatttttt
     3841 attttgtgaa taagatgtga aaaaatagag aatatgttag aatagagtca tgaaaattaa
     3901 agttgtaaca gttgggaaac tgaaagaaaa gtatttaaaa gatggtatcg cagagtattc
     3961 aaaacgaatt tctagatttg ctaagtttga aatgattgag ttatcagatg aaaaaacacc
     4021 agataaggcc agtgaatcag aaaatcaaaa gattttagaa atagaaggtc agagaatttt
     4081 atcaaaaatt gctgaccgtg atttcgttat tgtgttagcc attgaaggga aaactttctt
     4141 ctcagaagaa ttgagtaagc agttagaaga aacttctata aaaggatttt ctactcttac
     4201 ttttattatt gggggaagtt taggattgtc atcatctgta aaaaatagag ccaatctttc
     4261 tgtcagtttt ggtcgcctaa ccttgcctca tcagttaatg agactagttc ttgttgaaca
     4321 aatctatcgc gcttttacga ttcagcaggg attcccctac cataaataga aaattgactt
     4381 ttaattgaat ttttggtaga ataattgtgt taggtctcat agctcagctg gatagagcat
     4441 tcgccttcta agcgaacggt cgcaggttcg aatcctgctg ggatcaatat aatagcaaag
     4501 ctgggaattt tcccggcttt tttcttaaaa aagtacactt tgggagaaaa aaatgacagt
     4561 tgagagaatt ttatctaaaa cgaaattcca ttttgtataa tggtttttgt aagttagctt
     4621 acaagaaaaa aacattttag gagattttat tatgaaaaac acagttaaat tggaacagtt
     4681 tgtagctttg aaggaaaaag acttacaaaa gattaaaggt ggggagatga ggctgtcaaa
     4741 attcttccgt gattttattt tacaaagaaa aaagtaatga aataagggga aagagtaatg
     4801 gatttatttg gatttgggac agttattgtt cattttttaa ttattagtca caactaccat
     4861 ttaatttgta aaggtcaaat aaatagaaaa gaattattcg tttttggtgc ttatacatta
     4921 ctaacagaaa tagtatttga ttttccctta tatattctat atttagatgg gttagggatt
     4981 gcaacatttt tatttccttt gggcctatat tcctattttc gatggataaa acagtatgag
     5041 agggatagag gactattcct aagtttacta ctatctcttt tatatgagag cactcataac
     5101 tttctgtccg taactttctc ctctataaca ggagataatt ttgttttaca atatcatttc
     5161 ccattctttt tcgttgtgac ggtgttaacc tattttgtta cattaaaaat catttactat
     5221 ttccatttgg aactagccta ttttgacaag gactaccttt atcctttctt gaaaaaagta
     5281 ttttttgctt tactattgct acatattgta tctttcgttt cagatatggt aagtacgatt
     5341 aaacatttga atagttttgg aagtattttg tcatctattg tctttatctc tctccttttg
     5401 accttctttg caatgaattc tcataaagtt caaatggaga aagagattgc tttgaagcag
     5461 aagaaatttg aacagaaaca tttacagaat tacacagatg aaattgttgg tctgtataat
     5521 gaaatccgtg gttttcgaca tgattatgct ggaatgcttg tcagcatgca gatggcaatt
     5581 gacagtggta atttacagga aattgacaga atttacaatg aagttttagt caaagcaaat
     5641 cataaattgc gttcagataa gtacacttac tttgatttga acaacataga agactcagct
     5701 ttacgaagtt tggttgctca gtcaattgtc tatgctcgaa ataatggtgt agagtttaca
     5761 ctggaagtaa aagatacgat taccaagctt ccaattgaac tattggattt ggttcgtatc
     5821 atgagcgttt tattgaataa tgctgtcgaa ggatcggctg atagctataa aaagcagatg
     5881 gaagtagcag ttattaagat ggaaactgaa acagttattg tgattcagaa ttcatgtaaa
     5941 atgacgatga ctccttcagg agatctattt tccttaggat tctccactaa gggaagaaat
     6001 cgcggagtcg gattaaataa tgtgaaagaa ctactagata agtacaacaa tattatttta
     6061 gaaacagaga tggaaggcag tacatttaga caaatcatta gatttaagag ggaatttgaa
     6121 tgaaagtttt aattttagaa gatgttattg aacatcaagt gagactagag agaatattgg
     6181 atgaaatttc gaaagaatcg aatattccaa tatcatacaa gacaacggga aaagtccgtg
     6241 aatttgaaga atacattgaa aatgatgaag taaatcagct ttatttccta gatatcgata
     6301 ttcatggaat tgagaaaaag ggatttgaag tggctcagct cattcgtcat tacaatcctt
     6361 acgctattat cgtctttatc actagtcgat cagagtttgc gactctaacc tataaatacc
     6421 aggtatcagc cctagatttt gttgataagg atatcaatga tgagatgttt aagaagagaa
     6481 ttgagcaaaa tatcttctac acgaagagta tgttacttga aaatgaagat gttgtagatt
     6541 atttcgacta caattacaag ggaaatgatt taaaaattcc ttaccatgat attttgtata
     6601 ttgaaacaac aggggtatct cataaattgc gcattattgg taagaatttt gcaaaagagt
     6661 tttatggtac catgacagat attcaggaaa aggacaaaca tactcagcga ttttattctc
     6721 ctcacaagtc atttttggta aatataggca atatcagaga aattgatcga aaaaacttag
     6781 aaattgtttt ctatgaagac catcgttgtc ctatttcaag attaaaaatt agaaaattaa
     6841 aagatatttt agagaaaaaa tctcaaaagt gattgacaat tagcaagaaa ttgatataat
     6901 ggttatatct gctacagata gaaggtccgt tggtcaaggg gttaagacac cgccttttca
     6961 cggcggtaac acgggttcga atcccgtacg gactatttta tccgccatag ctcagttggt
     7021 agtagcgcat gactgttaat catgatgtcg taggttcgag tcctactggc ggagtataga
     7081 taaaagggaa cacagctgtg ttcctctttt tgtatcaatt tgtatcacca agcattttca
     7141 taaggaagtc tgttatttct tgagaacttt ctttttttcc atgtgcaatc caagtttggc
     7201 agacaccaaa aagtgcatga gttagataga tgctactata ttctaattca gtggtattta
     7261 gattcagttg cataaatcgc ttttgtaaat ctgtactaag catgatatga agtttatttc
     7321 gtaagaaatt ttggatttct ttagtcccat tttcagaaag aagggcagcc agaagtggtt
     7381 ctgactctag atattcaaaa acttctaaaa tagcgtctct tttgtgatga gcatgttttt
     7441 gaaaaatata ttcaaatgta tggaatagct tgctttgata gtgctcaatc atatcatact
     7501 tatccttata gtgagtatag aagctggaac gactaattcc ggctttttct actaatttga
     7561 cagtagaaat tttatcaaat ggctgttcca tcagtaattg taccatagca ttttcaatag
     7621 ttcgctttgt ttttaagcgt ttgttacttt cttgcatatt tcctccttgt aaataaatta
     7681 gactatatgt ctaaaaatag attttttatc ttgtaattta gattttttaa tgtataatct
     7741 attatatcaa aattttagac aatatgttta aaaaaggaga aactatgttt aaagaatgga
     7801 aagcaattta aaaaaaacaa cctttattat tgtcatgatc gggatttctc ttattccagc
     7861 tctgtacaat atcatatttt tgtcatcaat gtgggatcca tatgggcaat tgtctgactt
     7921 atctgtggca gttgtaaata atgataaaga ggcttcctat aatggtaata ctatggcaat
     7981 aggaaaagac atggtgtcca atttaaaaga aaataaaacc ttggattttc attttgtaga
     8041 tgaagaggaa ggaaagaagg gattggaaga tggcgattac tatatggtag tgactttacc
     8101 aagtgattta tctaaaaaaa caactacatt atccaatatt caatcgacag cagcttatca
     8161 atcattgaca agtgagcaac aaactgggat aagtgattct gtatctcaaa attcaactga
     8221 tagtattcaa tcggctcagt caattgtagc tttagtacaa ggtttacagg gaagtttaga
     8281 aaacttacaa aatcaatctt ctaatctttc gactttaaaa aatcaagcta atcaagtatt
     8341 acctattact tctacttctt tgataggatt gtcaagtgga ttaacagaga tacaaggagc
     8401 tgttactagc aaattagttc ctgccagtca gttgattgca tcaggtgtaa acgcatatac
     8461 tacaggtgtt gataaagttt ctcagggcgc aagtcaacta agtgaaaaaa atgccacctt
     8521 gacaggtagt ttggataaac tagtttcagg ctcaaacacc ttgacacaaa aatcttctag
     8581 attgacagca ggagttggtt aattacaatc aggatctggg caattagcag acaaatccag
     8641 tcagttactt tcaggtgctt ctccattaga gaatagagct aataaattgg cagatggatc
     8701 tgggaaacta gcagaaggtg gaacaaagtt aacttctgga ttggaagatt tacagacagg
     8761 acttgcttct ttaggacaag gactaggtaa tgctagtgat caactcaaat cagtatcaac
     8821 agaatctaaa aatgcagaga ttttgtcaaa tccactcaat ctttcaaaaa cagacaatga
     8881 tcaagttcct gtaaatggaa tcgcaatagc tccttatatg atatcagttg ctctttttgt
     8941 tgcagcaata tcaacaaata taatatttgc gaaattgcct tcaggacgtc atccagagag
     9001 ccgttggcct tggttgaaat ctcgagctga aataaatggt attatagctg ttttggcagg
     9061 aattttggta tatggaggag ttctattggt ttaactgcta atcatgagat gagaatattt
     9121 attctcatca tccaaacaag tttagtattc atgtctatgg tgaccacttt agcaacgtgg
     9181 aatagccgta taggagcttt tttctcactt attttgcttt tactatagtt agcatcaagt
     9241 gcaggtactt atccacttgc tttgacaaat gatttcttta gatctattaa tccctgttta
     9301 ccaatgagct attcagtttc gggattacga caaacaatct ctatcaacaa gtcattttcc
     9361 tagctgtcat actagctcta tttactggtt taggtatgct agcctatcaa cataagaaaa
     9421 tggaagaaga ttaaaaaaat cgaccgatta actggtcgat tttttatgcc ttagatgact
     9481 ttcgtctgtg attatagatt ccaaatagta agagagaagt aaaggaacag attgctccag
     9541 taataaaacc attgggaatg aaggaaagtg taatagttcc tttccccttg ggaatgtcaa
     9601 ctttcataaa tccagtttga gcttgtttaa tttctatttt cttaccatct tggtaggcag
     9661 accaaccttt gtcataagga atggtgaaga aaatagatgt atcttgttgg acatcatatg
     9721 tagcaaaaac cttgttttta taagttgata ctgtgacagg ttgttcttta attttttgaa
     9781 ttgcctcggt gaaagttttg gtatctaaac gatagaaggt aggagattca aatgatactt
     9841 gtgaatttcc agggaaacta acattgatat tgaaagtttt tttctcttta gtatatccta
     9901 gattaaagaa ggagaagaca ttatcagttg taaaagtctt tttttcacca tttacaagga
     9961 tgtcaacctt cttttgttta tcgttagaaa agtgaaggtt tatgaaagag agataaactt
    10021 ggctgttttc tggaacttca atttgatact ggattgctgc atcttcattt gaagaacttg
    10081 tgatactaat caaatcatta gtattttcta ttttttctgt tttttcataa ggtattggag
    10141 aaaaataatc aaaattgacg ttagcaagtt gatttaaaaa tgaggcctga ttatccaagg
    10201 tatgttcatt gaacttgaca tcattgtaaa cagattgact agcaactgca atcggaagag
    10261 agtattgatt ttcatatagg gtaagattat ctttttgata gatatcttta aagccatact
    10321 tatcaatagg actgtctgag atattgtact ggataccaaa taaactatca gccaaaatac
    10381 tattatttgc atatcggaga ttgagattag tcccagagga tttaaaacca agtttatcta
    10441 aagtagagct tgatgaacga tttcgaacag atgaaaattg agagattcca ttgtagttga
    10501 atttcatact gtcatttcct gtctgagttt gtagtttttc agtacgagta aattgatttc
    10561 caatatatgt tgagaaagat tccatagctg ggatatctcg actataagca cttcgagaag
    10621 caaatcccca ttccttagca attccgtcca tttgagatga agcatttaaa ctcatttcaa
    10681 ccagtataaa taaagagatt agaatggcaa atagattcac agatataaac tttttgataa
    10741 ctgcaaggag taaaagagaa tagacaacca aaaattcaag agtaagcaga atattcaaat
    10801 ctgttaaaaa agaataatgc gattttagat agatggtagc taaaaatcct gctactacaa
    10861 gaaaaagcga aactaaaaaa ttccagactt taagttcttt cagacgcttt aagacttctg
    10921 ctgctgtgta aattaacaag gtagagaaaa tccaagcata gcgatgtaaa aacatgtttg
    10981 gagtatgcat gccttgccaa aataagtcaa gagcttctat gtaaaagctt gcaattagaa
    11041 atgcaaagaa tattacatat atgagtttca cgtgaaactt aatagatttc agcgtaaaaa
    11101 ataaaatggt caaaataaag ggaaatagtc caacaaaaat cattgggatg gccccatact
    11161 ttgttgtgtc aaaggaacca atgaattgct tagcaaagag atcaagatac cagctacttt
    11221 cagtttgaaa ctttgtaact tcagtcaatt tttccccatg tgtctgtaaa tcaaatagag
    11281 tgggaagagt cataatcaaa ctagccatac cagctaaaaa ggagataact atgaaatcaa
    11341 gaacagatga ttttcgagtc ttaaagtccc acgaaatttg acagagatac cagaaaataa
    11401 gaaacaatac tgtcatatat ccaaaataat aattttgaat aaataagatt gacagacttg
    11461 taaagtacaa taggagtttc ttttcagtta tcagtagatg taaaccagtt ataattaaag
    11521 gaatcaagat aaaaacatct agccaggttt ttatctctaa ttgactgaca gtgaaactca
    11581 tcagagcata ggaagtagat aaggctagtt ttaaagcctg agggatagat tgaaacaatt
    11641 tattcaaact aaaaaaggtt gacagaccaa tcaatccaaa ttttaagaga gttgtcagat
    11701 agatagcatc tggcatattc gttagatcaa aaaagtaaac cagaggcgcg agaaaactac
    11761 ccaagtaata actagatagg gcatagaagt ttagccctag accacttgta aaggtgtaaa
    11821 acagactact atttccatgt aggatatttc gtaaggctac atcaaaaata acgtattgat
    11881 gaaagccatc tcctaataga ggagagttgt cgctattcca gtagatacct tgagatagat
    11941 atactccaga cataatcact acaggaatga tgaaagaaat aaaataggtt cgatatgttt
    12001 ttaaaaatga tttcatgtta cctcgtagaa tgatagaaaa ctcagttggt taacccaact
    12061 gagttttgaa gttttattta gtctttccaa agttctttaa cttttgcttg tacttctgca
    12121 ttttctagga attcatcgta ggtttcatcg atacggtcaa tgacgccatt tttagataag
    12181 acaatgatat ggttagccaa agtttgaata aattcgtggt catggctggc aaagatgatt
    12241 gattctttaa agtttttcaa tccatcattc aagcttgaga tagattccaa gtccaagtga
    12301 tttgttggat catcaagtac aaggacattt gattttaaga gcatgagttt tgaaagcatg
    12361 acacgaactt tttctccccc tgacaagaca tttacaggtt tgttaacttc atctccagag
    12421 aagagcatac ggccgaggaa gccacgtagg aaagtattgt catcttcttc tttacttgcg
    12481 aattgacgca accagtcaag aattgattct cctcctgcaa aatcagctga gttatctttt
    12541 ggtaggtaag attgactagt tgtaactccc cacttgacag ttccttcata gtcaatatct
    12601 cccatgattg cacgaattaa tgcagtcgtt tgaatatcat tttgtccaat aagtgctgtc
    12661 ttatcatctg gacgcaagat gaaactaata ttatccaaga tagtttcacc atcaatcttt
    12721 acagttagat tttctactgt caagagatca ttaccaatct cacgttccgc tttaaagttg
    12781 ataaatggat atttacgact agatggtaca atctcttcta gctcaatctt atcaagcatt
    12841 ttcttacgtg atgttgcctg ccttgactta gaagcattgg cagagaaacg agcaacgaat
    12901 tcttgcaatt gtttaatttt ttcttctgct ttagcattac ggtctgctag caatttagca
    12961 gcaagctcag aagattcctt ccagaagtcg tagtttccga catagagttt gatttttcca
    13021 aagtcaaggt cggccatgtg agtacaaact ttgtttaaga agtgacggtc gtgggatact
    13081 acgataactg tgttatcaaa gtcaatcaag aagtcttcta accaagtaat cgattggata
    13141 tccaaaccgt tagtaggctc gtccaagaga agaacatctg gtttaccaaa aagtgctttg
    13201 gcgaggagaa cctttacttt ttcaccgttg gccaattcgc tcatgttttg gtagtgtaat
    13261 tcttctggaa tgtttaggtt ttgaagtagt tgagaggctt cactctctgc ttcccaacct
    13321 ccaagttcgg caaactctcc ttcgagttcg gcagcacgaa ccccgtcctc gtctgagaaa
    13381 tcttccttca tgtagatagc atctttctct ttcatgatgc tataaagttt ttcatttccc
    13441 atgataacga catcaatggc acgttcatct tcgtagtcaa agtgattttg acgaagaaca
    13501 gagagacgtt catctggacc aagagagatg tgaccagtag taggttcgat atctccagct
    13561 aaaattttta aaaaggttga ttttccggca ccattagcac cgattaatcc gtaagtattt
    13621 ccttctgtaa atttgatatt gacatcatca aaaagtttgc gatcactaaa acgtagtgaa
    13681 acatcagata ctgtaagcaa tatttttctc ctatatgtgt aatatattta ttctactaga
    13741 aaatacagaa atattcaaat ttttatttgt caattttgtg taaattatat ttacagtatc
    13801 ctttacacaa atctgtaaaa agcaaggctg atttattttg ataaattacg gttatttcat
    13861 taaaaaaatg ctataattga aaggactata tcgaaggaga acaaaatgac taaacccatt
    13921 attttaacag gagaccgtcc aacaggaaaa ttgcatattg gacattatgt tggaagtctc
    13981 aaaaatcgag tattattaca ggaagaggat aagtatgata tgtttgtgtt cttggctgac
    14041 caacaagcct tgacagatca tgccaaagat cctcaaacca ttgtagagtc tatcggaaat
    14101 gtggctttgg attatcttgc agttggattg gatccaaata agtcaactat ttttattcaa
    14161 agccagattc cagagttggc tgagttgtct atgtattata tgaatctagt ttcgttagca
    14221 cgtttggagc gaaatccaac agtcaagaca gagatttctc agaaaggatt tggagaaagc
    14281 attccgacag gattcttggt ctatccaatc gctcaagcag ctgatatcac agctttcaag
    14341 gctaattatg ttcctgttgg gacagatcag aaaccaatga ttgagcaaac tcgtgaaatt
    14401 gttcgttctt ttaacaatgc atataactgt gatgtcttgg tagagccgga aggtatttat
    14461 ccagaaaatg agagagcagg gcgtttgcct ggtttagatg gaaatgctaa aatgtctaaa
    14521 tcactaaata atggtattta tttagctgat gatgcggata ctttgcgtaa aaaagtaatg
    14581 agtatgtata cagatccaga tcatatccgc gttgaggatc caggtaagat tgagggaaat
    14641 atggttttcc attatctaga tgtttttggt cgtccagaag atgctcaaga aattgctgat
    14701 atgaaagaac gttatcaacg aggtggtctt ggtgatgtga agaccaagcg ttatctactt
    14761 gaaatattag aacgtgaact gggtcctatt cgtgagcgcc gtattgaatt tgctaaggat
    14821 atgggagaag tttataatat gattcaaaaa ggtagtgaaa gagcgcgtga agttgcgggt
    14881 caaaccctat ctgaggtaaa aggggcaatg ggacttcatt actttaatta agtttatttt
    14941 acaagaaact atcatttcta tctcgaagaa aagatagttt tttatttacc cctgtaacat
    15001 ttgacaaatt tttatagaat ggtatgatag atacaatata aaaagagtca agctcaaaaa
    15061 gaaagaaaag aggaaacttc gaatgtctaa ttgggacact aaatttttga aaaaaggttt
    15121 tacctttgat gatgtattgc ttattccagc tgaaagtcat gtgttgccta acgatgcaga
    15181 tttaacaact aaattggcag ataatttgac tttaaatatc ccaattatta ccgctgccat
    15241 ggacacagtt acagagagtc aaatggccat tgctattgct cgtgcaggtg gtctcggagt
    15301 tatccataaa aacatgtcaa ttgctcaaca agcagacgag gttcgtaagg taaaacgttc
    15361 tgaaaatgga gttattattg atccgttctt cttgacgcct gaacatacaa ttgctgaagc
    15421 agatgagctt atgggtcgtt accgcatcag tggtgttcca gttgttgaaa cacttgaaaa
    15481 tcgtaaattg gttggtattt tgacaaaccg agatcttcgt tttatttcag attataatca
    15541 accaatttca aaccatatga ctagtgaaaa tcttgttact gctcctgtgg gtacggatct
    15601 tgcaacggct gagagtattc ttcaagagca tcgtattgaa aaacttccgt tggtcgatga
    15661 agaaggcagt ctttctggtt tgatcactat caaagatatt gaaaaagtta ttgagtttcc
    15721 aaatgcggct aaagatgaat ttggtcgtct tctagttgca ggtgcagtag gtgttacttc
    15781 agatacattt gaacgtgcag aggctctttt tgaggcagga gcggatgcga ttgttattga
    15841 tactgcacat ggtcattctg caggtgtctt gcgtaaaatt gccgagattc gtgctcattt
    15901 cccagatcgg actttgattg ctggaaatat tgctactgct gaaggtgcac gtgcccttta
    15961 tgaagcgggt gtagacgttg ttaaggttgg tattggacca ggttctatct gtactactcg
    16021 tgtgattgct ggtgttggtg ttccgcaagt aacagctatc tacgatgctg cagctgttgc
    16081 gcgcgaatat ggtaaaacga ttattgctga cggtgggatc aagtattctg gagatattgt
    16141 aaaagcactt gctgcaggtg gaaatgctgt tatgcttgga tctatgtttg ctggaactga
    16201 tgaagctcca ggcgaaactg aaatcttcca aggacgtaaa ttcaagactt accgtggtat
    16261 gggatcaatt gctgctatga agaaaggttc aagcgaccgt tatttccaag gttctatcaa
    16321 tgaagcaaac aagctcgttc cagaaggaat tgaaggtcgt gttgcttata aaggagcggc
    16381 agctgatatt gttttccaaa tgattggtgg tattcgctct ggtatgggtt actgtggtgc
    16441 agctaacctt aaagaactac acgataatgc tcaatttatt gaaatgtctg gtgctggttt
    16501 gaaagaaagc catcctcatg atgtgcaaat tactaatgag gcaccaaatt attctatgta
    16561 aaaaacaatg aaaagaactc cagtgaaaac aggagttctt ttacaatgtt gtcaatttcc
    16621 atttacagca gctttaccat cctgaatagt gaagatactt agattttctg gtagattttg
    16681 aagatggtct aagcttgttg ttgtgataaa ggtttggatt gattgagaaa tcgtttctaa
    16741 taattttaat tgtctagtgt tgtcaagttc actcatcaca tcgtcaagca gtaatatagg
    16801 agattctgtg gtaatgcttt ccattaattc gatttctgct aattttatcg agaggacgag
    16861 actacgatgt tgaccttggc ttccgaaact agcatccatc ccatttatat aaaaagaaat
    16921 gtcatctcga tgaggaccga caccagtatt ctttttaaat aaatctctgg atttactttt
    16981 ttctaaagca attttgaaag attcggataa gttttgtttg tcagttatat tgacagaaga
    17041 ttgataggat attgacaact cttcgatctg attagagagt tcaaaatgtt tcttacgccc
    17101 aaatgattct agttttttta tgaaatctaa gcggtgattc attacacgac atccataatc
    17161 aactagctga tcatctaaca cagaaaggaa tgtttcatct attttttgat ctgattttag
    17221 gtaagtgttt ctttgcttta ggatgtggtt ataattggtt aagtcagata agtagattgg
    17281 cttaatttgc ccaagttcca tatcgatgaa ttttcgtcga atcgaaggtg ctcctttaat
    17341 tagttgtaaa tcttcaggag caaataagac aacattcatg tgtcctacat aatctgaaag
    17401 gcgtgcctgt tttaagtgat taacttttgt tacacggcct ttttgtgtta gttcgatttc
    17461 taggggaatg gatccagttt ttttctgaac gagacctgaa agatgaagtt gttcctcatc
    17521 aaaatgaatg agatttttat ctgttcgagt tcgatgacta cgcgttaagg ctaaaaaata
    17581 gatagcctct aacatgtttg tttttccttg tgcattacgt cccaaaaaga cattcaattt
    17641 aggattaaag tctattttcg tttctttgta attacgaaaa gtcttgagag atagatgttg
    17701 tagccacatg attatctacc agggaatcgt ggagcttgtt ggcttttagg tgatgaagca
    17761 ggtttcgatt tgtctttttt aactccctta ttcatctttt tgacaagttt agcgatccgt
    17821 tctttttcaa ctttatcagc ttggtattca tcttgttctt cagaagtagg ttgtgtcaac
    17881 aagatgtcaa tgttcatgtc agggatgtca actttatcgc caatacgaag tttttttcca
    17941 cgacgactct ctaattccct attaaagtaa acagaatgtt cagagagaaa tgatttaata
    18001 gctcctccgc tatgtgtaat tccaagttct ttgagtagtg cttggagggt aataaattct
    18061 tcaaataatt tgtattccat aattcacctc aatctttggt attataccat attttcctaa
    18121 aaatagtgag agagacagcg agaaatgtaa gcgattttta tttcaaaagt gttacaggga
    18181 acaagaaaat ttcaggtttt cgtgatataa tagaagtctg tatataagga ggtaaatcat
    18241 ggagttagtg catggaattt caacacattt tatccaatca aaaaagttta aaacaaacaa
    18301 aattaccgtg cgttttaccg ctccattatc ccttgatacg attgcaggtc acatgttgag
    18361 tgcaagtatg ctagagactg ctaatcagat gtaccccact tctcaagatt tgaggagaca
    18421 cttggccagt ctatacggta cagatatgtc aaccaattgt ttcagaagag ggcaaagcca
    18481 cattatagaa ttgacattta cctatgttcg tgatgagttt ttaagtagga aaaacgtgct
    18541 aacctctcag attttggaac ttgtaaaaga aactcttttt tcacccgtag tagttgataa
    18601 tgggtttgat ccggccttat ttgaaattga gaaaaaacaa ttgctagcaa gtttagcagc
    18661 tgatatggat gattcttttt attttgcaca taaagaattg gataaattgt tttttcatga
    18721 tgaacgtctt caattggaat atagtgattt acgaaatcgt attttagctg aaactccaca
    18781 aagttcttac tcttgtttcc aagaattttt agccaatgat cgaatagatt tctttttcct
    18841 aggtgatttt aatgaggttg aaattcaaaa tgtattagaa tcatttggct ttaaaggtcg
    18901 aaaaggagat gtgaaggttc agtattgtca accttattct aatatccttc aggaaggtat
    18961 ggttcggaaa aatgtgggac aatccatttt ggaattaggt tatcattacc gttctaaata
    19021 tggtgatgaa caacatttac ccatgattgt aatgaatggt ttacttggtg gatttgctca
    19081 ctctaagctc tttacaaatg tccgtgaaaa tgctggatta gcttatacca tttcaagtga
    19141 gcttgattta tttagtggat tcttgaggat gtatgctggt atcaatcgag aaaatcgtaa
    19201 ccaggctcgt aaaatgatga ataatcaact gcttgattta aaaaaaggtt attttacaga
    19261 gtttgagtta aatcagacca aggaaatgat tcgttggtcg ttgttacttt ctcaagataa
    19321 tcaatcttca ttgattgaac gtgcttatca aaatgcctta tttggaaaat cttcagcaga
    19381 ctttaaaagt tggattgcaa agcttgaaca aattgacaaa gatgctattt gtagagtagc
    19441 taataatgtg aaactacaag cgatttactt tatggaagga atagaatgac aaaggttgtt
    19501 tttgaagaaa aatactatcc agctgtaaaa gaaatggttt atcgaactcg tttggccaac
    19561 ggattgacag ttgctctttt gcctaaaaag gaatttaaag aggtttacgg gagtgtcact
    19621 gtacagtttg gttcggtaga tacgtttgtc acagaagttg acggagatgt aaaacaatat
    19681 cctggaggaa ttgctcattt tcttgaacat aaattatttg agagagaaga ttctagtgat
    19741 ttgatgtcgg cttttacgag tctaggtgca gatagtaatg cctttacaag ctttacaaaa
    19801 acaaactatc ttttttcagc aacggattat tttttagaaa atttagattt acttgatgaa
    19861 ttggtaacat cagcacactt tactgaagct tccattttga cagagcagga tattattcag
    19921 caagaacgag aaatgtacca agatgatcca gattcgtgtt tattcttttc aactttagcg
    19981 aatttgtatc ctggtacacc tttagcaact gatatagttg gaagtgagga gtccatttcc
    20041 caaatcaatc taactaattt gcaagaaaat tttacaaagt tttacaaacc tgtaaacatg
    20101 tctctgtttt tagttggtaa ttttgatgtg gagcgagtac aggactattt tgaaagcaaa
    20161 gaactgaaag attcagattt tcaggaagta gcaagagaaa agttgttttt acagcctgta
    20221 aagccaacag atagtatgag aatggaagta tcttctccca aactagcgat tggagttaga
    20281 ggtaagcgag aagtttctga agcggattgc tatcgacatc atattttatt aaaattattg
    20341 tttgcaatga tgtttggttg gacttcgaat cgttttcaaa aatgttatga atcaggtaaa
    20401 attgatgcat ccttatctct ggaagttgaa gtaacaagtc gctttcattt tgtcatgttg
    20461 acaatggata cgaaagagcc agttgctttg tctcatcaat ttaggaaggc tattcgtaat
    20521 tttacaaagg atttagatat tacagaggaa catttagata ttatcaaaag agagatgttt
    20581 ggcgaatttt tcagtagcat gaactctctt gaatttattg caacgcaata tgatgctttt
    20641 gaaaatggtg agacaatttt tgatttgccg aaaattttac aggaaattac tttagaggat
    20701 gtccttgatg ctggacatca tttaatagat gatggtgaca tagttgattt tacaatattc
    20761 ccatcgtagt aacctattat aatagacact agaaagaagg gatgacaagt atgagaaaaa
    20821 aaacaattgg agaggtttta cgattagcta gaatcaatca gggattgagt ttagatgaat
    20881 tgcagaaaaa gacagaaatc cagttagata tgttggaagc aatggaagca gacgatttcg
    20941 atcaacttcc aagtcctttt tacacgcgtt ctttcttgaa aaaatatgca tgggctgttg
    21001 agttagatga ccaaattgtt ttggatgctt atgattctgg gagtatgatt acttatgagg
    21061 aagtagatgt tgatgaagat gagttgacag gtcgtagacg ttcaagtaag aaaaagaaga
    21121 aaaaaacatc atttttacct ttattttatt ttatcctttt tgctttatcg attttaattt
    21181 ttgtgactta ttatgtttgg aactatattc aaactcaacc agaggagcct tctctttcta
    21241 attacagtgt ggttcaatca acaagttcaa ctagctctgt tccccactcc tcaagtagta
    21301 gttcttctag tatagaatca gctataagtg tatcaggcga aggaaatcat gtagaaatcg
    21361 cttataagac aagtaaggaa acagttaaat tgcaattggc agtttcagat gttacaagtt
    21421 gggtcagtgt ttcagaaagc gaacttgagg gcggtgtaac cttatcgcca aagaagaaaa
    21481 gtgcagaagc aacagttgca actaaaagtc ctgtaacaat tacgttaggt gttgtaaaag
    21541 gtgttgattt gacagtagat aatcagactg ttgatttatc gaaattaaca gctcagactg
    21601 gacaaatcac tgtaaccttt actaaaaatt aaggaaaaac gaatgaaaaa agaacaaatt
    21661 cccaatctct taacaatagg tcgaattctc tttataccta tttttatctt tattttaacg
    21721 ataggaaatt cgatagagag tcatatagtt gcagctatta tctttgctgt tgccagtatt
    21781 accgactatt tagatggata tttagctcgt aaatggaatg tggtcagtaa ttttggtaaa
    21841 tttgcagatc ctatggcgga taagttacta gttatgtcgg cttttattat gttgattgag
    21901 ttaggtatgg ctccggcttg gattgttgca gtgattatct gtcgtgagtt agctgtgaca
    21961 ggtttaaggc ttttattggt tgaaactggt ggaacaattt tagcagcagc aatgcctgga
    22021 aaaattaaaa cttttagtca gatgtttgct attattttct tgctattaca ttggactttg
    22081 cttggtcaag ttctacttta tgtagcctta tttttcacta tctactctgg ctatgactat
    22141 ttcaagggta gtgcctatgt atttaaaggg acatttggtt cgaaatgaaa tcaataattg
    22201 atgtaaaaaa tctttctttt cgctataaag aaaatcagaa ctactacgat gtgaaggata
    22261 ttacgtttca cgtgaaacgt ggagaatggc tttcgattgt agggcataat ggtagtggta
    22321 aatcaactac ggttcgatta attgatggct tactggaagc agaatccgga gagattgtaa
    22381 ttgatggcca acgtttgact gaggaaaatg tttggaatat acgtcgtcaa atcggtatgg
    22441 tttttcaaaa tccagacaat caatttgttg gagcgactgt tgaagatgat gttgcttttg
    22501 gtttggaaaa tcagggactt tctcgtcaag aaatgaaaaa gagagtggaa gaagctctgg
    22561 ctttagttgg catgttggac tttaaaaaga gagagccagc gcgtctatca ggtggtcaaa
    22621 agcaacgtgt ggccattgca ggtgttgtag ccctaagacc agctatttta atcttagatg
    22681 aagcaacgag tatgttggat cctgaggggc gtagagaact tattgggaca gtaaaaggaa
    22741 ttcgaaaaga ctatgatatg acggtcattt ctattaccca tgatttggaa gaagtcgcca
    22801 tgagtgatcg cgtattggtc atgaaaaaag gggaaattga atcaactagt agtccaaggg
    22861 agcttttctc tcgaaatgat ttagatcaaa ttggattaga cgatcctttt gctaatcaat
    22921 taaaaaaatc tttgagccag aatggctatg atttacctga aaattatttg acagaaagtg
    22981 agctagagga taagctatgg gaattgctct agaaaatgtg aattttacat atcaagaagg
    23041 tactccctta gcttcagcag ctttgtcgga tgtttctttg acgattgaag atggctctta
    23101 tacagcttta attgggcaca caggtagtgg taaatcaact attttacaac tcttaaatgg
    23161 tttattggtg ccaagtcaag ggagtgtgag ggtttttgat accttaatca cctcgacttc
    23221 taaaaataaa gatattcgtc aaattagaaa acaggttggc ttggtatttc agtttgctga
    23281 aaatcagatt tttgaagaaa cggttttgaa ggacgttgct tttggaccgc aaaattttgg
    23341 agtttctgaa gaagatgctg tgaagactgc gcgtgagaaa ctggctctgg ttggaattga
    23401 tgaatcactt tttgatcgta gtccgtttga gctgtcaggg ggacaaatga gacgtgttgc
    23461 cattgcaggc atacttgcca tggagccagc tatattagtc ttagatgagc caacagctgg
    23521 tctagatcct ctagggagaa aagagttgat gaccctgttc aaaaaactcc accagtcagg
    23581 gatgaccatc gtcttggtaa cgcatttgat ggatgatgtt gctgaatatg caaatcaagt
    23641 ctatgtaatg gaaaagggac gtttagtaaa ggggggcaaa ccaagtgatg tctttcaaga
    23701 cgttgttttt atggaagaag ttcagttggg agtacctaaa attacggcct tttgtaaacg
    23761 attggctgat agaggcgtgt catttaaacg attaccgatt aagatagagg agttcaagga
    23821 gtcgctaaat ggatagtatg attttggggc gttatatccc aggggattcg attgttcacc
    23881 gattggatcc acgtagcaaa ttgcttgcta tgatgctact gattttgatt gtgttttggg
    23941 ctaataaccc cttgacgaat ctgattcttt ttatagcgac agggatattt attgccttgt
    24001 caggagtatc tctttcattt tttattcagg gcttgaagtc tatgtttttc ttgattgcct
    24061 tcacaactat ttttcaacta tttttcattt ctaatgggaa tgttttattt gagttttcgt
    24121 ttgtgagaat cacggattat gctttgcaac aagctgggat tattttttgt cgctttgtat
    24181 tgattatttt cttttcaact ttgttaacct taacaaccat gcctttaagt ttggcatcag
    24241 ctgtcgaagc tttattagca cctttaaagc gtgtgaaagt tccagttcat gaaattggat
    24301 tgatgctgtc tatgagtttg cgttttgtcc caaccttgat ggatgatacg actcggatta
    24361 tgaatgcaca gaaagctcgt ggagtggatt ttggagaagg aagcatcgtt caaaaagtaa
    24421 aggcgatgat tcccattttg attcctcttt ttgcgacaag tttaaaacgt gcagattcct
    24481 tggctatcgc tatggaagcg cgtggctatc agggtggaaa aggcagaagt caataccgac
    24541 aattgaaatg gactctaaag gatacgctga ccattcttgt tattctcgta cttggttgtt
    24601 gtttattttt cttaaaatct tagtagcttt caggaattga taaaaagtta ctgtaacagt
    24661 ttttgatata aaggtaggga tatgaaccgt tttaaaaaat caaaatatgt cattattgtt
    24721 tttgtcactg ttctgcttgt gtcagctctc ttagcgacga cttattcaag tacaattgtg
    24781 acaaaattag gagatggaat ctcattggtt gatagagttg tacaaaaacc ttttcagtgg
    24841 tttgattctg tcaaatcaga tttggctcat ttgacacgaa catataatga aaatgaaagt
    24901 ttgaagaaac agctttacca attagaagtt aaatcaaatg aggtggaaag tttaaagaca
    24961 gaaaatgaac aactgcgcca attgcttgat atgaagtcta aattgcaagc cacaaagact
    25021 ttagcagcag atgttattat gcgttctccg gtatcttgga agcaggagtt gaccttagat
    25081 gcaggtagat caaaaggtgc ttctgagaac atgttagcta ttgcaaatgg tggcttgatt
    25141 gggagtgttt caaaagtaga ggagaactct actatagtca accttctgac aaatacggaa
    25201 aatgctgata agatttctgt taaaattcaa catggctcta ctacaattta tggaattatt
    25261 attggctatg acaaggaaaa tgacgttctt aaaattagcc aattaaatag taatagcgat
    25321 attagtgcgg gagataaggt gactactggt ggattaggaa actttaacgt tgctgatatt
    25381 cctgttggtg aagtggttgc cacaacgcat agtacagact atttgacacg agaagtaact
    25441 gttaaattga gtgcagatac tcataatgta gatgtgatag aattagtggg gaattcataa
    25501 tgagacagtt gaagcgagtt ggagtatttt tattgcttcc tttctttgtt ctaattgacg
    25561 cccatattag ccagcttctg ggctcatttt tcccccatgt acatttggct agtcattttc
    25621 tttttctatt tctcttattt gagacgatag aagtatcaga gtatctctac ctagtctatt
    25681 gttttgttat aggcttggtt tatgatgttt actttttcca tctaataggg attacaactc
    25741 tcttatttat cttattggga gccttccttc ataaattgaa tagtgttatt ttgttgaatc
    25801 gttggacaag aatgctagct atgattgtgc tgacattcct gtttgaaatg ggtagttatc
    25861 ttttggcttt tatggtaggg ttgacagtag atagcatgtc gatttttata gtctatagct
    25921 tggtaccgac gatgatttta aattttttat ggattactgt ttttcaattt atttttgaaa
    25981 aatattatct ataagaacga catataaatg taacaaaggc gtaatattta ttaggccttt
    26041 ttttggtata ctagtattgt ctttaaaaga aggagtatct acgtaatatg aagaaaaaaa
    26101 tcttagcgtc acttttatta agtacagtaa tggtttctca agtagctgtt ttaacaactg
    26161 cgcatgcaga aacgactgat gacaaaattg ctgctcaaga taataaaatt agtaacttaa
    26221 cagcacaaca acaagaagcc caaaaacaag ttgaccaaat tcaggagcaa gtatcagcta
    26281 ttcaagctga gcagtctaac ttgcaagctg aaaatgatag attacaagca gaatctaaga
    26341 aactcgaggg tgagattaca gaactttcta aaaacattgt ttctcgtaac caatcgttgg
    26401 aaaaacaagc tcgtagtgct caaacaaatg gagccgtaac tagctatatc aataccattg
    26461 taaactcaaa atcaattaca gaagctattt cacgtgttgc tgcaatgagt gaaatcgtat
    26521 ctgcaaacaa caaaatgtta gaacaacaaa aggcagataa aaaagctatt tctgaaaaac
    26581 aagtagcaaa taatgatgct atcaatactg taattgctaa tcaacaaaaa ttggctgatg
    26641 atgctcaagc attgactacg aaacaggcag aactaaaagc tgctgaatta agtcttgctg
    26701 ctgagaaagc gacagctgaa ggggaaaaag caagtctatt agagcaaaaa gcagcagctg
    26761 aggcagaggc tcgtgcagct gcggtagcag aagcagctta taaagaaaaa cgagctagcc
    26821 aacaacaatc agtacttgct tcagcaaaca ctaacttaac agctcaagtg caagcagtat
    26881 ctgaatctgc agcagcacct gtccgtgcaa aagttcgtcc aacatacagt acaaacgctt
    26941 caagttatcc aattggagaa tgtacatggg gagtaaaaac attggcacct tgggctggag
    27001 actactgggg taatggagca cagtgggcta caagtgcagc agcagcaggt ttccgtacag
    27061 gttcaacacc tcaagttgga gcaattgcat gttggaatga tggtggatat ggtcacgtag
    27121 cggttgttac agctgttgaa tcaacaacac gtatccaagt atcagaatca aattatgcag
    27181 gtaatcgtac aattggaaat caccgtggat ggttcaatcc aacaacaact tctgaaggtt
    27241 ttgttacata tatttatgca gattaattta cagagggact cgaatagagc cctcttttca
    27301 ggttttaccg tgacaatccc tattaaaaat tatatcaaaa tagcttgaaa atattggaaa
    27361 agtatggtag aatgaaaatt gtcgtgtgaa cgataatact cattcttgat gaattgtgaa
    27421 gcagttgccc ttgggtcgtt ttgcgagttg aagtcaagaa gaggaaaaaa acaaaaagga
    27481 gaaatactca tggcagtaat ttcaatgaaa caacttcttg aggctggtgt acactttggt
    27541 caccaaactc gtcgctggaa tcctaagatg gctaagtaca tctttactga acgtaacgga
    27601 atccacgtta tcgacttgca acaaactgta aaatacgctg accaagcata cgacttcatg
    27661 cgtgatgcag cagctaacga tgcagttgta ttgttcgttg gtactaagaa acaagcagct
    27721 gatgcagttg ctgaagaagc agtacgttca ggtcaatact tcatcaacca ccgttggttg
    27781 ggtggaactc ttacaaactg gggaacaatc caaaaacgta tcgctcgttt gaaagaaatt
    27841 aaacgtatgg aagaagatgg aactttcgaa gttcttccta agaaagaagt tgcacttctt
    27901 aacaaacaac gtgcgcgtct tgaaaaattc ttgggtggta tcgaagatat gcctcgtatc
    27961 ccagatgtga tgtacgtagt tgacccacat aaagagcaaa tcgctgttaa agaagctaaa
    28021 aaattgggaa tcccagttgt agcgatggtt gacaccaata ctgatccaga tgatatcgat
    28081 gtaatcatcc cagctaacga tgacgctatc cgtgctgtta aattgatcac agctaaattg
    28141 gctgacgcta ttatcgaagg acatcaaggt gaggatgcag tagcagttga agcagaattt
    28201 gcagcttcag aaactcaagc agattcaatt gaagaaatcg ttgaagttgt agaaggtgac
    28261 aacgcttaat ttatacaaat agtaattacc taggagggcg gggcttagcc cggctctcct
    28321 attttcaaaa aatataggag aattaaaatg gcagaaatta cagctaaact tgtaaaagag
    28381 ttgcgtgaaa aatctggtgc cggtgttatg gacgctaaaa aagcgcttgt agaaacagac
    28441 ggtgacatcg aaaaagcgat tgaattgctt cgtgaaaaag gtatggctaa ggcagctaag
    28501 aaagctgacc gtgttgctgc agaaggtttg actggtgttt atgttaacgg taatgttgca
    28561 gcagttattg aagtaaacgc tgaaactgac ttcgttgcaa aaaacgctca attcgttgaa
    28621 ttggtaaata ctacagctaa agtcattgct gaaggaaaac ctgctaacaa tgaagaagct
    28681 cttgctttga taatgccttc aggtgaaact cttgaagctg catacgtatc tgcaacagca
    28741 actatcggag agaaaatctc attccgtcgc tttgcattga ttgaaaaaac agacgcacaa
    28801 cactttggag cataccaaca taacggtgga cgtatcggtg ttatttcagt tgttgaagat
    28861 ggagacgaag cacttgctaa acaattgtca atgcacatcg cagcgatgaa accaacagtt
    28921 ctttcttaca aagaattgga tgagcaattc gttaaagatg agttggcaca attgaatcac
    28981 gttatcgacc aagacaacga aagccgtgca atggttaata aaccagctct tccacacttg
    29041 aagtatggat caaaagctca attaactgat gatgttattg ctcaagctga agctgacatc
    29101 aaagctgaat tggctgcaga aggcaaacca gaaaaaatct gggacaaaat tattccaggt
    29161 aaaatggatc gcttcatgct tgataacact aaagttgacc aagcttacac acttcttgca
    29221 caagtttaca tcatggatga cagcaagaca gttgaagcat accttgaatc agttaacgct
    29281 tcggtagttg agtttgctcg ctttgaagtt ggtgaaggta tcgagaaagc tgcaaacgac
    29341 ttcgaagctg aagttgcagc tacaatggca gcagccttga ataactaata atagaaagga
    29401 agcaaattgc ttcctttttt gtatagggct tagatttttc ctgaaattgt tttttcccca
    29461 gtctcactcg attagaataa ttaaaacaaa aagccctata ataagggcta agtgcattta
    29521 ggagactata cttcaaattc atagtaagcg cgtcataaca aggtatctat cctaattccc
    29581 caacttccag tatactagat aaaaaataat tatcggagga aaggtattgt actatgataa
    29641 ttcaactaag tgatttaggt caagttcacc ttgtttgtgg caagacagat atgaggtagg
    29701 gaatagactc attagcctat gtagttaaaa cccactttga attggattct ttctccggtc
    29761 aagtctttct cttttgtggt ggacgtaaag accgctttaa agccctttac tgggatggtc
    29821 aaggattttg gctactatat aaacgctttg agaacggaaa actgacttgg ctaagtacag
    29881 aaaaggatgt caaagctctc gcacctgaac aagtagattg gcttatgaag ggcttttcta
    29941 tcactccaaa aatatagtag attgaaacta gaatagtaca cctctgcttc taaaacattg
    30001 ttagaaatcg atttgattgt cctgttctta tttcatttta ctataaatcc atcagaaagt
    30061 tgtgatttct attgaaatga ggactttctt tttacactca tctgctttca aaaagcattc
    30121 tagtccatct ccgattaacg atggacttta tcacctcctt ctccagtcct tgtatgacat
    30181 cttccaaagt tcgaaaggct ttattcttaa atccacgttt acgaatctct ttccacactt
    30241 gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaagcca atattagtcg
    30301 gaatctttaa ggtacttgat ttatgccata tagcattgtc cataacgagt aaaagataat
    30361 catctggata agcttgtgaa agctcctatt cctaaagccc ctttagcgca tagctttggc
    30421 tcagcttcta ttatcgctca caccatccat cagaagttta atctgaaggt acccaattat
    30481 cgccaagaag aagattgggc taagatgggt ttaccaatca cacgcaagga aatctctaat
    30541 tggcatatca agacgagtca atactatttg gagcccctct ataacctctt gcgagagaga
    30601 ctattgactc agcccttact tcatgcggat gaaacttctt atagggtgct agagagtgat
    30661 agtcagctga cttactattg gacttttttg tctgggaaag ctgagaaaca agggattacg
    30721 ctttaccatc atgtcctaat cgatttgttc atatcttatt tcaatccatt ataaatagtg
    30781 agaaatatct atcctatctt ctagaatgtc ttccaaacgt ggaaactctc gtaaacaaag
    30841 aggttttaga ggcttattta ccatggacta aagttgtaca agaaaagtgc aaataagaaa
    30901 tctccagatt aggaactatc cgtgagttct ctagtctgga gatttttcaa tatacttcgt
    30961 tattggacgg ttacaattca taaagtgctg tagagagata acgttcaccg ttatctggtg
    31021 ctaggacaag gactttttta cctgtaccta attttttggc aacctcgatg gctccgtaga
    31081 tagctgcagc tgaggaaatc cctacaagga agccttcttt tccaccaatt tcacgtccga
    31141 gtgcaagagc gtcatctgat gttacacgaa cgataccatc ataggcttta gtatcaagtg
    31201 tatcaggaat aaatccagct gagatacctt gaattttgtg aggaccaggt ttttcaccag
    31261 atagaatagc agattcatct gcttctactg caaaaacttg aatgttagaa ttttctgatt
    31321 tgagtgcatg agaaacacca gaaatcgttc caccggtacc tactccagca acaaaggcat
    31381 ctaatccatc tttaccgaaa gcagctagta tctcagctcc tgttgttctt tcgtgtactt
    31441 ctggattagc tggattgtca aattgaagag gaaggaaacc atcacgttca gcagcgattt
    31501 cttgagcctt agcaatagca cctttcattc cctcgctacc aggagttagg acgagttcag
    31561 caccataagc ttggataatt ttacgtcgtt ctacactcat agtttcaggc ataacgatga
    31621 cgactttata ccctttagca gcacctaccc atgaaagtcc aataccagtg tttccacttg
    31681 ttgcttcaac aatagtagaa ccaggtttca gaataccatc ttgttcagct ttttcaatca
    31741 tgctaagggc aatacggtct tttacagatg aaccaggatt aaatgcttca agctttatat
    31801 agacgtctgc agcaccttct ggcacgatgt tgttaagttt aacaatcggt gtttgaccga
    31861 ttaattcagt aatgttgtta taaatagaca tatgaatacc tctttgtata agatatcttt
    31921 agtataacgc tatccatacc atttgtaaaa tatagaaatc ctatcgaagc gataggattt
    31981 ctatatatca tagatcaaag tcattaattt tcaagtgatt gcgttcagtt aattctagta
    32041 aataggtgtg aaggaaaacg atatcaggtt tcgtttgaat tgcttcattt tctagtatat
    32101 tttggtacgc atctttttat tttgctcgct aaagtagttg tgagaatgtc aacgaaacgc
    32161 tgtattattc attgtttaca ctaagtttac aggaacttca acctctcgta aaccttggtc
    32221 agttaaagtg acttttccat taaaaaactc cacaagtgca gctttaatag tttctttttc
    32281 ttctttatca acataaatca tcgtatcgac ttgatctgta aagtttgtat ccagctccat
    32341 gagatcatgt tctttaagga agttactgta ctcttggtac tgagcataag acatttgaat
    32401 agcaatgcca gcctgttctt ttatttcaat aataccaatt tctttgacag ctaaggcgac
    32461 actgccggcg taagcacgaa ttagtcctcc agcgcctagt ttaataccac caaagtagcg
    32521 tgtcacgacc acacagacat tggtgagatt gtgattttct agtaccccaa gcatgggaac
    32581 accagcagta ccactaggct caccatcatc acttgtacgt ttaatttcac tacgttctcc
    32641 aataataaag gcagagcagt tatgtgtcgc tttgtagtgt tcttttttga tggcagtaat
    32701 gaagtcacga gcctcttctt cgctataaac acgcttggca tggcagataa agcgagattt
    32761 tttgatttct tcttggactt ggccgtcctc tttaattgtc ctaaattcca tgatttaatt
    32821 gtactaaaaa ataatctaaa gtgctagttt ttacgaataa agaagtatga aagtaaattt
    32881 agattatctc ggtcgtttat ttactgagaa tgaattaaca gaagaagaac gtcagttggc
    32941 ggagaaactt ccagcaatga gaaaggagaa ggggaaactt ttctgtcaac gttgtaatag
    33001 tactattcta gaagaatggt atttgcccat cggtgcttac tattgtcgag agtgcttgct
    33061 gatgaagcga gtcagaagtg atcaaacttt atactatttt ccgcaggagg attttccgaa
    33121 gcaagatgtt ctcaaatggc gcggccaatt aactcctttt caagagaagg tgtcagaggg
    33181 actgcttcaa gcagtagaca agcaaaagcc aaccttagtt catgcggtaa caggagctgg
    33241 aaagacagaa atgatttatc aagtagtggc taaagtgatc aatgcgggtg gtgcagtgtg
    33301 tttggctagt cctcgcatag atgtttgttt ggagctgtac aagcgcctgc aacaggattt
    33361 ttcttgcggg atagctttgc tacatggaga atcggaacct tattttcgaa caccactagt
    33421 tgttgcaaca acccatcagt tattgaagtt ttatcaagct tttgatttgc tgatagtgga
    33481 tgaagtagat gcttttcctt atgttgataa tcccacgctt taccacgctg tcaagaatag
    33541 tgtaaaggag aatggattga gaatcttttt aacagcgact tcgaccaatg agttagataa
    33601 aaaggtccgt ttaggagaac taaaaagact gagtttaccg agacggtttc atggaaatcc
    33661 gttgattatt ccaaaaccaa tttggttatc ggattttaat cgctacttag acaagaatcg
    33721 tttgtcacca aagttaaagt cctatattga gaagcagaga aagacagctt atccgttact
    33781 catttttgct tcagaaatta agaaagggga gcagttagaa gaaatcttac aggagcaatt
    33841 tccaaatgag aaaattggct ttgtatcttc tgtaacagag gatcgattag agcaagtaca
    33901 agcttttcga gatggagaac tgacaatact tatcagtacg acaatcttgg agcgtggagt
    33961 taccttccct tgtgtggatg ttttcgtagt agaggccaat catcgtttgt ttaccaagtc
    34021 tagtttgatt cagattggtg gacgagttgg acgaagcatg gatagaccga caggagattt
    34081 gcttttcttc catgatgggt taaatgcttc aatcaagaag gcgattaagg aaattcagat
    34141 gatgaataag gaggctggtc tatgaagtgc ttgttatgtg ggcagactat gaagactgtt
    34201 ttaactttta gtagtctctt acttctgagg aatgatgact cttgtctttg ttcagactgt
    34261 gattctactt ttgaaagaat tggggaagag aactgtccaa attgtatgaa aacagagttg
    34321 tcaacaaagt gtcaagactg tcaactttgg tgtaaagaag gagttgaagt cagtcataga
    34381 gcgattttta cttacaatca agctatgaag gattttttca gtcggtataa gtttgatgga
    34441 gacttcctgt taagaaaagt tttcgcttca tttttaagtg aggagttgaa aaagtacaaa
    34501 gagtatcaat ttgttgtaat tcccctaagt cctgatagat atgctaacag aggatttaat
    34561 caggttgagg gcttggtaga ggcagcaggc tttgagtatc tggatttatt agagaaaaga
    34621 gaagagagag ccagttcttc taaaaatcgt tcagagcgct tggggacaga acttcctttc
    34681 tttattaaaa gtggagtcac tattcctaaa aaaatcctac ttatagatga tatctatact
    34741 acaggagcaa ctataaatcg tgttaagaaa ctgttggaag aagctggtgc taaggatgta
    34801 aaaacatttt cccttgtaag atgaggaaaa aatttgcaaa aatagaatga aagcgttata
    34861 ataaaatcat aaaaacaaaa atgtttagaa agaaggtact catatgatta aatatagtat
    34921 ccgtggtgaa aacctagaag taacagaagc aattcgtgat tatgtagttt ctaaactcga
    34981 aaagatcgaa aagtacttcc aaccagaaca agagttggat gcccgaatta acttaaaagt
    35041 ttatcgtgaa aaaacggcta aagtggaagt aacgattccg cttggatcta ttactctccg
    35101 cgcagaagat gtatctcaag atatgtatgg ttcaattgac cttgtaactg ataaaattga
    35161 acgtcagatt cgtaaaaata aaacaaaaat cgagcgtaaa aataaaaata aggtagcaac
    35221 tggtcaatta tttacagatg ctttggtgga agattcaaat attgtccagt ctaaagttgt
    35281 tcgttcaaaa caaattgatt taaaaccaat ggatttggaa gaagcaattc tacaaatgga
    35341 tttattgggg catgatttct ttatctatgt ggatgttgaa gatcagacaa ccaatgtgat
    35401 ttatcgtcgt gaggatggcg aaattggttt gttagaggtt aaagaatctt aatttcaata
    35461 tgtgtaaagg taggtttact gaattgtaaa ctaccttttt cttataattg atagaattac
    35521 tgattacact tttaaaaagt cgctttttga ggggtattat ggtataatgg gtgccaagag
    35581 gttttgaatg aaaaaatttt atgtaagtcc aatttttcct attctagtag gattgattgc
    35641 gtttggagtc ttatccactt tcattatttt tgttaataat aatctgttga cggttttaat
    35701 tttgtttctt tttgtaggag gctatgtttt tttatttaag aaactgagag tgcattatac
    35761 aaggagtgat gtagaacaga tacagtatgt aaaccaccaa gcggaagaaa gtttgacagc
    35821 tctattggaa cagatgcctg taggtgttat gaaattgaat ttatcttctg gagaggttga
    35881 gtggtttaat ccctatgctg aattgatttt gaccaaggaa gatggtgatt ttgatttaga
    35941 agctgttcaa acgattatca aggcttcagt aggaaatccg tctacttatg ccaagcttgg
    36001 tgagaagcgt tatgctgttc atatggatgc ttcttccggt gttttgtatt ttgtagatgt
    36061 atccagggaa caagccataa cagatgaatt ggtaacaagt cgaccagtga ttgggattgt
    36121 ctctgtggat aattatgatg atttggagga tgcaacttct gagtcagata ttagtcaaat
    36181 caatagtttt gtagctaatt ttatatcaga gttttcagaa aaatacatga tgttttctcg
    36241 tcgggtaagt atggatcgat tttatctatt tactgactac acggtgcttg agggcttgat
    36301 gaatgataaa ttttctgtta ttgatgcttt cagagaagag tcgaaacaga gacagttgcc
    36361 cttgacctta agtatgggat tttcttatgg cgatggaaat catgatgaga tagggaaagt
    36421 tgctttgctc aatttgaact tggctgaagt acgtggtggc gaccaggtgg ttgttaagga
    36481 aaacgacgaa acgaaaaatc cagtttattt tggtggtggg tctgctgctt caatcaagcg
    36541 tacacggact cgtacgcgcg ctatgatgac agctatttca gataagattc ggagtgtaga
    36601 tcaggttttt gtagtcggtc acaaaaattt agacatggat gctttgggct ctgctgtagg
    36661 tatgcagttg ttcgccagca atgtgattga aaatagctat gctctttatg atgaagaaca
    36721 aatgtctcca gatattgaac gagctgtttc attcatagaa aaagaaggag ttacgaagtt
    36781 gttgtctgtt aaggatgcaa tggggatggt gaccaatcgt tctttgttga ttcttgtaga
    36841 ccattcaaag acagccttaa cattatcaaa agaattttat gatttattta cccaaatcat
    36901 tgttattgac caccatagaa gggatcagga ttttccagat aatgcggtta ttacttatat
    36961 cgaaagtggt gcaagtagtg ccagtgagtt ggtaacggaa ttgattcagt tccagaattc
    37021 taagaaaaat cgtttgagtc gtatgcaagc aagtgttttg atggctggta tgatgttgga
    37081 tactaaaaat ttcacctcgc gagtaactag tcggacattt gatgttgcta gctatctcag
    37141 aacgcgcgga agtgatagta ttgctatcca ggaaatcgct gcgacagatt ttgaagaata
    37201 tcgtgaggtc aatgaactta ttttacaggg gtgtaaatta ggttcagatg tactaatagc
    37261 agaggctaag gacacgaaat gctatgatac agttgttatt agtaaggcag cagatgccat
    37321 gttagccatg tcaggtattg aagcgagttt tgttcttgcg aagaatacac aaggatttat
    37381 ctctatctca gctcgaagtc gtagtaaact gaatgtacaa cggattatgg aagagttagg
    37441 cggtggaggc cactttaatt tggcagcagc tcaaattaaa gatgtaacct tgtcagaagc
    37501 aggtgaaaaa ctgacagaaa ttgtattaaa tgaaataaag gaaaaggaga aagaagaatg
    37561 aaagtaatct ttttagcaga tgttaaagga aaaggtaaaa aaggcgaaat taaggaagta
    37621 ccaacagggt atgcgcaaaa ctttcttatc aaaaagaatc tagccaaaga agcgactgct
    37681 caagctgtag gtgaacttcg tggtaaacaa aaatcggaag aaaaagctca cgctgagatg
    37741 attgcagaag gaaaagcaat taaagcacaa cttgaagcag aagaaactgt tgtagaattt
    37801 gttgaaaaag ttggtccaga tggtcgtacc tttggttcta ttaccaataa gaagattgca
    37861 gaagaattgc aaaagcaatt tggaattaag attgataaac gtcatattca agtacaagct
    37921 ccgattcgag cggttggttt gattgatgtg ccagtgaaaa tctatcaaga tatcacaagt
    37981 gtaatcaatc ttcgtgtgaa agaaggataa gtttacactt tcttgacaag attgtaaaag
    38041 aagggaagtc tgatggcaga agtagaagag ttacgagtac aacctcaaga tatcttagct
    38101 gagcaatccg ttttaggggc tatctttatt gatgagagta aacttgtttt tgtgcgagaa
    38161 tacattgagt ctcgggactt ttttaagtat gcccatcgtt tgattttcca agccatggtc
    38221 gatttatccg atcgtggtga tgccatagat gcaacaacgg ttcgtactat ccttgataat
    38281 caaggtgatt tacagaatat tggtggcttg tcttacttgg ttgagattgt taattctgtg
    38341 ccaacttctg ctaatgcgga gtattatgct aagattgttg cagaaaaagc aatgctacgt
    38401 cgtttaattg ccaagttgac agagtctgtc aaccaagctt acgaagcgtc acaaccagct
    38461 gatgaaatta ttgctcaggc agaaaaaggg ttgattgatg tcagtgaaaa tgcaaatcga
    38521 agcgggttta agaacattcg agatgtgttg aatctcaact ttggaaatct ggaagctcgc
    38581 tcgcaacaaa cgaccgatat tacaggtatt gcgacaggtt atcgtgattt ggatcatatg
    38641 acaacaggac ttcatgagga ggagttgatt atcttagcag ctcgtccagc agttggtaag
    38701 acagcatttg ccttgaatat cgctcagaat attgggacta agttggacaa aacggttgct
    38761 attttttcac tcgaaatggg tgcggaaagc ttggtagatc gtatgttagc tgcagaaggc
    38821 ttagtggagt cacattctat ccgtacaggg caattgacag atgaggagtg gcaaaaatat
    38881 actattgctc agggtaatct agctaacgcc agtatctata tcgatgatac gccaggtatt
    38941 cggattacag agattcgttc tcgttctcgt aaattggctc aagaaactgg aaatcttggt
    39001 ttgattttga tagactattt gcaacttatc acgggaactg gtcgagaaaa tcgtcaacaa
    39061 gaagtttctg aaatttctcg tcagttgaaa atactagcca aggaattgaa ggttccagta
    39121 atcgctctga gtcagctttc tcgtggtgta gaacaacgtc aggacaagag accggtcttg
    39181 tctgatattc gtgaatctgg gtctattgag caggacgctg atatcgtagc ttttctctat
    39241 cgcgatgact actatgaacg tggtggtgaa gaagaggagg gtatcccaaa taataaggtg
    39301 gaagttatta tcgagaaaaa ccgtagtgga gctcgtggaa cagtggaatt gattttccaa
    39361 aaagaataca ataaattttc aagtatctca aagagggagg cataagatgt cagatgcatt
    39421 tacagatgta gccaagatga aaaaaatcaa agaagaaatc aaggcacatg agggacaagt
    39481 cgtagaaatg actttggaga atggtcgtaa gcgccaaaaa aatagattgg gtaagctaat
    39541 tgaagtttat ccatctctat ttattgtgga gtttggggat gtggaaggag ataaacaagt
    39601 taatgtttac gttgaatcct ttacttactc agatattctt acagaaaaga atttgattca
    39661 ttatcttgac taaagtgaga aattttctca ctttttcttt tttctccgaa taatttaggt
    39721 gaaggcaatc atcgctttat attatttttc aaggaggaag aatgaaaatt ttaccgttta
    39781 tagcaagagg gacaagttat tacttgaaga tgtcagttaa aaagcttgtt ccttttttag
    39841 tagtaggatt gatgctagca gctggtgata gtgtctatgc ctattccgga ggaaatggat
    39901 cgattgcgcg cggggatgat tatcctgctt attataaaaa tgggagccag gagattgatc
    39961 agtggcgcat gtattctcgt cagtgtactt cttttgtagc ctttcgtttg agtaatgtca
    40021 atggttttga aattccggca gcttatggaa atgcgaatga atggggacat cgtgctcgtc
    40081 gggaaggtta tcgtgtagat aatacaccga cgattggttc cattacttgg tctactgcag
    40141 gaacttatgg tcatgttgcc tgggtgtcaa atgtaatggg agatcagatt gagattgagg
    40201 aatataacta tggttataca gaatcctata ataaacgagt tataaaagca aacacgatga
    40261 caggatttat tcattttaaa gatttggatg gcggcagtgt tgggaatagt caatcctcag
    40321 cttcaacagg cggaactcat tattttaaga ccaagtctgc tattaaaact gaacccctag
    40381 ctagcggaac tgtgattgat tactattatc ctggggagaa ggttcattat gatcagatac
    40441 ttgaaaaaga cggctataag tggttgagtt atactgccta taatggaagc tatcgttatg
    40501 ttcaattgga ggctgtgaat aaaaatcctc taggtaattc tgttctttct tcaacaggtg
    40561 gaactcatta ttttaagacc aagtctgcta tcaaaactga acccctagtt agcggaactg
    40621 tgattgatta ctattatcct ggagagaagg ttcattatga tcagatactt gaaaaagacg
    40681 gctacaagtg gttgagttat actgcctata atggaagtcg tcgctatata cagctagagg
    40741 gagtgacttc ttcacaaaat tatcagaatc aatcaggaaa tatctctagc tatggatcca
    40801 ataatagttc aactgtcggt tggaagaaaa taaatggtag ttggtatcat ttcaaatcaa
    40861 atggttctaa atcaacagga tggctgaaag acggttctag ctggtattat ttgaaattat
    40921 ctggtgaaat gcagacagga tggttaaagg agaatggctc gtggtattat ctgggtagtt
    40981 caggggcaat gaaaacaggc tggtaccagg tctctggtaa gtggtattat tcttactctt
    41041 caggcgcctt agctgttaat acgacggtgg atggctacag agtaaacagt gatggagaac
    41101 gagtatagaa aattggagta ggagaaattt cctgctcttt tctgtaagca gtttccttga
    41161 catttttctt attttgcgct atcatatata catataatat atgggagtct gtgtacagtc
    41221 tgagaggaag tgttaaactt cgaccgcacc tgatctgggt aatgccagcg gagggaacga
    41281 tacttagtct aattttgcac cttttccatg tatggtaaag gtttttcttt ttttaaaaag
    41341 gaaaacgaga agaggaggtt cttatgaaag caagcattgc cttgcaagtt ttacccctag
    41401 cacaggggat tgatcggata gctgttattg atcaggtcat tgcttatctg caaactcaag
    41461 aagtgacgat ggtagtgaca ccatttgaaa cggtcttgga aggggagttt gatgagctta
    41521 tgcgcattct aaaagaagcg ctggaagtgg cagggcagga ggcagacaat gtctttgcca
    41581 atgtcaaaat aaatgtagga gagattttaa gtattgatga gaaacttgag aagtatactg
    41641 agacgacaca ttagtctatt gggctttctc ggagtcttgt taatctggca gttagcaggt
    41701 tttcttaaac ttctccccaa gtttatcctg ccgacacctc ttgaaattct ccagcccttt
    41761 gttcgtgaca gagaatttct ctggcaccat agctgggcga ccttgagagt ggctttactg
    41821 gggctgattt tgggagtttt gattgcctgt cttatggctg tgctcatgga tagtttgact
    41881 tggctcaatg acctgattta ccctatgatg gtggtcattc agaccattcc gaccattgcc
    41941 atagctccta tcctggtctt gtggctaggt tatgggattt tgcccaagat tgtcttgatt
    42001 atcttaacga caacctttcc catcatcgtt agtattttgg acggttttag gcattgcgac
    42061 aaggatatgc tgaccttgtt tagtctgatg cgggccaagc cttggcaaat cctgtggcat
    42121 tttaaaatcc cagttagcct gccttacttt tatgcaggtc tgagggtcag tgtctcctac
    42181 gcctttatca caactgtggt atctgagtgg ttgggaggtt ttgaaggtct tggtgtttat
    42241 atgattcagt ctaaaaaatt gtttcagtat gataccatgt ttgccattat tattctggtg
    42301 tcgattatca gtcttttggg tatgaagctg gtcgatatca gtgaaaaata tgtgattaaa
    42361 tggaaacgtt cgtagaatta gaatgtttct gaaaaagaaa agaggaaatc aaaatgaaga
    42421 aaacatggaa agtgttttta acgcttgtaa cagctcttgt agctgttgtg cttgtggcct
    42481 gtggtcaagg aactgcttct aaagacaaca aagaggcaga acttaagaag gttgacttta
    42541 tcctagactg gacaccaaat accaaccaca cagggcttta tgttgccaag gaaaaaggtt
    42601 atttcaaaga agctggagtg gatgttgatt tgaaattgcc accagaagaa agttcttctg
    42661 acttggttat caacggaaag gcaccatttg cagtgtattt ccaagactac atggctaaga
    42721 aattggaaaa aggagcagga atcactgccg ttgcagctat tgttgaacac aatacatcag
    42781 gaatcatctc tcgtaaatct gataatgtaa gcagtccaaa agacttggtt ggtaagaaat
    42841 atgggacatg gaatgaccca actgaacttg ctatgttgaa aaccttggta gaatctcaag
    42901 gtggagactt tgagaaggtt gaaaaagtac caaataacga ctcaaactca atcacaccga
    42961 ttgccaatgg cgtctttgat actgcttgga tttactacgg ttgggatggt atccttgcta
    43021 aatctcaagg tgtagatgct aacttcatgt acttgaaaga ctatgtcaag gagtttgact
    43081 actattcacc agttatcatc gcaaacaacg actatctgaa agataacaaa gaagaagctc
    43141 gcaaagtcat ccaagccatc aaaaaaggct accaatatgc catggaacat ccagaagaag
    43201 ctgcagatat tctcatcaag aatgcacctg aactcaagga aaaacgtgac tttgtcatcg
    43261 aatctcaaaa atacttgtca aaagaatacg caagcgacaa ggaaaaatgg ggtcaatttg
    43321 acgcagctcg ctggaatgct ttctacaaat gggataaaga aaatggtatc cttaaagaag
    43381 acttgacaga caaaggcttc accaacgaat ttgtgaaata atgacagaaa ttagactaga
    43441 gcacgtcagt tatgcctatg gtcaggagag gattttagag gatatcaatc tacaggtgac
    43501 ttcaggcgaa gtggtttcca tcctaggccc aagtggtgtt ggaaagacca ccctctttaa
    43561 tctaatcgct gggattttag aagttcagtc agggagaatt gtccttgatg gtgaagaaaa
    43621 tcccaagggg cgcgtgagtt atatgttgca aaaggatctg ctcttggagc acaagacggt
    43681 gcttggaaat atcattctgc ccctcttgat tcaaaaggtg gataaggcag aagctatttc
    43741 ccgagcggat aaaattcttg cgaccttcca gctgacagct gtaagagaca agtatcctca
    43801 tgaacttagc ggtgggatgc gccagcgtgt agccttactc cggacctacc tttttgggca
    43861 caagctcttt ctcttagatg aggcctttag cgccttggat gagatgacaa agatggaact
    43921 ccacgcttgg tatcttgaga ttcacaaaca gttgcagcta acaactctga tcatcacgca
    43981 tagtattgag gaggccctca atctcagcga ccgcatctat atcttgaaaa atcgccctgg
    44041 gcagattgtt tcagaaatta aactagattg gtctgaagat gaggacaagg aagtccaaaa
    44101 gattgcctac aaacgtcaaa tcttggcaga attaggctta gaataagtag aaaaataggg
    44161 agttggtgaa gattatcctt taccagcgcc ctttttcttt taaaaatgag aaaatttcgg
    44221 tataatagtc aaacaaggtc aaggtttaaa gagagaggtg ggtttgttat gagatttaaa
    44281 aatacatcgg atcatattga ggcctacatc aaggcgattt tagatcaatc tggtatcgtg
    44341 gagttgcaac ggagtcagtt ggcagatacc tttcaggttg ttcctagtca gattaactac
    44401 gtgatcaaga cacgctttac ggaaagtaga ggctacttgg ttgaaagtaa gcgtggtggc
    44461 ggaggctaca ttcgtatagg acggattgag ttttctagtc atcatgaaat gctccgggat
    44521 ctgctttact cgattggtga gcgagtcagt caagaaattt atgaggatat tctccagctt
    44581 ttggttgagc aggaattgat gaccaagcag gagatgaatt tgctagaatc agtagctttg
    44641 gatcgcgttt taggagaaga agctccagtt gttcgagcaa acatgctacg tcaggtcata
    44701 caagaggtag atagaaaagg gaagtaagat gaactattca aaagcattga atgaatgtat
    44761 cgaaagtgcc tacatggttg ctggacattt tggagctcgt tatctagagt cgtggcactt
    44821 gttgattgcc atgtctaatc acagttatag tgtagcaggg gcaactttaa atgattatcc
    44881 gtatgagatg gaccgtttag aagaggtggc tttggaactg actgaaacgg actatagcca
    44941 ggatgaaacc tttacggaat tgccgttctc ccgtcgtttg caggttcttt ttgatgaagc
    45001 agagtatgta gcgtcagtgg tccatgctaa ggtactaggg acagagcacg tcctctatgc
    45061 gattttgcat gatggcaatg ccttggcgac tcgtatcttg gagagggctg gtttttctta
    45121 tgaagacaag aaagatcagg tcaagattgc tgcccttcgt cgaaatttag aagaacgtgc
    45181 aggctggact cgtgaagatc tcaaggcttt acgccaacgc catcgtacag tagctgacaa
    45241 gcaaaattct atggccaata tgatgggcat gccgcagact cctagtggtg gtctcgagga
    45301 ctatacgcat gatttgacag agcaagcgcg ttctggcaag ttagaaccag tcatcggtcg
    45361 ggacaaggaa atctcacgta tgattcaaat cttgagccgt aagactaaga acaaccctgt
    45421 cttggttggg gatgctggtg tcgggaaaac agctctggcc cttggtcttg cccagcgtat
    45481 tgctagtggt gacgtgcctg cggaaatggc taagatgcgc gtgttagaac ttgatttgat
    45541 gaatgtcgtt gcagggacac gcttccgtgg tgactttgaa gaacgcatga ataatatcat
    45601 caaggatatt gaagaagatg gccaagtcat cctctttatc gatgaactcc acaccatcat
    45661 gggttctggt agcgggattg attcgactct ggatgcggcc aatatcttga aaccagcctt
    45721 ggcgcgtgga actttgagaa cggttggtgc cactactcag gaagaatatc aaaaacatat
    45781 cgaaaaagat gcggcacttt ctcgtcgttt cgctaaagtg acgattgaag aaccaagtgt
    45841 ggcagatagt atgactattt tacaaggttt gaaggcgact tatgagaaac atcaccgtgt
    45901 acaaatcaca gatgaagcgg ttgaaacagc ggttaagatg gctcatcgtt atttaaccag
    45961 tcgtcacttg ccagactctg ctatcgacct cttggacgaa gcagcagcaa cagtgcaaaa
    46021 taaggcaaag catgtaaaag cagacgattc agatttgagt ccagctgaca aggccctgat
    46081 ggatggcaag tggaaacagg cagcccagct aatcgcaaaa gaagaggaag tacctgtcta
    46141 caaagacttg gtgacagagt ctgatatttt gaccaccttg agtcgcttgt caggaatccc
    46201 agttcaaaag ctgactcaga ctgacgctaa gaaatatcta aatcttgaag cagaactcca
    46261 taaacgggtt atcggtcaag atcaagctgt ttcaagtatt agtcgtgcga ttcgccgtaa
    46321 tcagtcagga attcgcagtc acaagcgtcc gatcggttcc tttatgttcc taggacccac
    46381 aggtgtcggt aagaccgagt tggccaaggc tttggcagaa gttctctttg atgacgaatc
    46441 agcccttatc cgctttgata tgagtgagta tatggagaaa ttcgcagcca gccgtctaaa
    46501 tggagctcct ccaggctatg tgggttacga agaaggtggg gagttgacag agaaggttcg
    46561 caataaaccc tattccgttc tcctctttga tgaggtagag aaggctcacc cagatatctt
    46621 taatgttctc ttgcaggttc tggatgacgg tgtcttgaca gatagcaagg gacgcaaggt
    46681 cgatttttca aataccatta tcattatgac atcgaaccta ggtgcgactg cccttcgtga
    46741 tgataagact gttggttttg gggctaagga tattcgtttt gaccaggaaa atatggaaaa
    46801 acgcatgttt gaagaactga aaaaagctta tagaccggaa ttcatcaacc gtattgatga
    46861 gaaggtggtc ttccatagcc tatctagtga tcatatgcag gaagtggtga agattatggt
    46921 caagccttta gtggcaagtt tggctgaaaa aggcattgac ttgaaattac aagcttcagc
    46981 tctgaaattg ttagcaaatc aaggatatga cccagagatg ggagctcgcc cacttcgcag
    47041 aaccctgcaa acagaagtgg aggacaagtt ggcagaactt cttctcaagg gagatttagt
    47101 ggcaggcagc acacttaaga ttggtgtcaa agcaggccag ttaaaatttg atattgcata
    47161 aaagaataaa agtaccagca tctgaccata agtcacagtg gagtgaaact caatgaaaat
    47221 caaagagcaa actaggcagc tagccgcagg ttgctcaaaa cactgttttg aggttgcaga
    47281 tagagctgac gtggtttgaa gagattttcg aagagtataa gctgcaagat gaatgatttt
    47341 cttgtattga cgttgttgtt gacaaaaagt agcggataaa tgaaatccat tctattatca
    47401 tagatgatag gctggtagga aattttcaaa tagcatacag gaaatagatg tatggagttc
    47461 tggtagtaga aagggagaga gatgaacatt ttagttgcag atgacgagga aatgattaga
    47521 gaaggaattg cagcatttct gacagaagag ggttatcatg tcattatggc taaggatgga
    47581 caagaggtct tggaaaaatt tcaagatctc cctatccatc tcatggtact ggatttaatg
    47641 atgcctagga agagtggttt tgaagtgtta aaagaaatca atcaaaagca cgatattcct
    47701 gtcatcgtct tgagtgctct gggagatgaa attactcagt cacaggtatt tgatctctat
    47761 gctgatgatc atgtgacaaa acctttttct ttggtactgc ttgtcaagcg tattaaggcg
    47821 cttatcagac gttactacgt catagaggat atttggcgat atcaggatgt aacagtggat
    47881 tttacctctt acaaagcaca ttataaaaat gaagaaattg atctcaaacc aaaggaatta
    47941 ctggtactaa agtgtttgat tcagcataaa aatcaagttt taagtagaga gcagatattg
    48001 gaagaaattt caaaagatgt agctgattta ccttgtgata gggtcgttga tgtctatatt
    48061 cgtactcttc gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa tgttgggtat
    48121 aagattagtt tatgataaaa aatcctaaat tattaaccaa gtccttttta agaagttttg
    48181 caattctagg tggtgttggt ctagtcattc atatagctat ttatttgacc tttccttttt
    48241 attatattca actggagggg gaaaagttta atgagagcgc aagagtgttt acggagtatt
    48301 taaagactaa gacatctgat gaaattccaa gcttactcca gtcttattca aagtctttga
    48361 ccatatctgc tcaccttaaa agagatattg tagataagcg gctccctctt gtgcatgact
    48421 tggatattaa agatggaaag ctatcaaatt atatcgtgat gttagatatg tctgttagta
    48481 cagcagatgg taaacaggta acagtgcaat ttgttcacgg ggtggatgtc tacaaagaag
    48541 caaagaatat tttgcttttg tatctcccat atacattttt ggttacaatt gctttttcct
    48601 ttgttttttc ttatttttat actaaacgct tgctcaatcc tcttttttac atttcagaag
    48661 tgactagtaa aatgcaagat ttggatgaca atattcgttt tgatgaaagt aggaaagatg
    48721 aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg aaggttattt
    48781 atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag gtttcctttg
    48841 tccgcggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt atcctagaga
    48901 atatgcagca taatattgga gattacaaag atcatccaaa atatattgca aagagtataa
    48961 ataagattga ccagatgagc cacttattgg aagaagtact ggagtcttct aaattccaag
    49021 agtggacaga gtgtcgtgag actttgactg ttaagccagt tttagtagat attttatcac
    49081 gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg acagatgcta
    49141 ccagagtcgt catgagtctt agggcattgg ataaggtttt gacaaacctg attagtaatg
    49201 caattaaata ttcagataaa aatgggcgcg taatcatatc cgagcaagat ggctatctct
    49261 ctatcaaaaa tacatgtgcg cctctaagtg accaagaact agaacattta tttgatatat
    49321 tttatcattc tcaaatcgtg acagataagg atgaaagttc cggtttgggt ctttacattg
    49381 tgaataatat tttagaaagc tatcaaatgg attatagttt tctcccttat gaacacggta
    49441 tggaatttaa gattagcttg tagacagatt agttttttat taaagttcat atagggttaa
    49501 cataagtgtg ttattctttg tgtagataaa agaaaggata ctaatatggt attagcgatt
    49561 attttagtaa cattctttat tcgattgatt tttttaaagc gttcgataga gaatgagaaa
    49621 cgaatcctta gcaatggcgg gaaagaattt ggagttgaga atacaaaacg attaactatg
    49681 gctcatattg ttttttatct ctcttgcttg gttgaggcaa tggtgcacaa gacaattttt
    49741 gatggcatgg gcatggttgg tttagtcttg cttatttttt ctatgctgat gttgatgttg
    49801 gtgattcact tgttgggaga tatttggaca gtgaagctta tgcttgtcaa taatcacaaa
    49861 tatgtagatc atatcttgtt taggacagta aaacacccta attacttttt aaatatttta
    49921 cctgagttga ttggcttgac cttgttgagt catgcctata tgacttttgt tttagttttt
    49981 ccagtttatg cagttatttt gtatcgacga atagctgaag aggaaaagct attacatgaa
    50041 gttataatcc caaatggaag cataaagaga taaatacaaa attcgactca tatacagttc
    50101 atattgaagt gatatagtaa ggttaaagaa aaaatataga aggaaataaa catgtttgca
    50161 tcaaaaagcg aaagaaaagt acattattca attcgtaaat ttagtattgg agtagctagt
    50221 gtagtagttg ccagcttgtt cttaggagga gtagtccatg cagaaggggt taggagtaag
    50281 aataacctca cggttacatc tagtgggcaa gatatatcga agaagtatgc tgatgaagtc
    50341 gagtcgcatc tacaaagtat attgaaggat gtcaataaaa atttgaaaaa agttcaacat
    50401 acccaaaatg tcgacttcaa caaaaagttg agcagaatta aaacgaagta tttgtatgga
    50461 ttaaaagaga agtcggaagc tgagttgacg ttaaaaacaa aagaaacaaa agaagagtta
    50521 accgcagctt ttgagcagtt taaaaaagat acattgaaat caggaaaaaa ggtagcagaa
    50581 gctgagaaaa aagccaaagc tcaaaaagaa gaagatcgcc gtaactaccc aaccaatact
    50641 tacaaaacaa tcgaactgga aattgcggaa gcagaagtag gggtcgccaa ggcagagctt
    50701 gagcttgagt ttgcacaagc tcaagttcaa atacctcaag atactgagaa aattaatgct
    50761 gctaaatcta aagtagaagc tgctaaaagt aatgttaaaa aactagaaaa aattaaatca
    50821 gatattgaaa aaacgtattt gtataaatta gataactcaa ccaaagaaac gccaaaatct
    50881 agagtgcgaa gaaattctcc gcaagtaggc gattcgagag aacttaagga aacgatagac
    50941 aaagcgaaag aaactctgtc tacctatatg gtaactcgtt taacgaagct ggatccatct
    51001 gttttttggt ttgcagatct tcttatggat gctaagaagg ttgtggaaga atacaagaca
    51061 aaattagagg atgcttcaga taaaaaatcg gtagaagact tgcgaaagga agcagaagga
    51121 aaaatagagt ctcttatcgt gactcaccaa aatagagaaa aagaaaacca accagcaccc
    51181 caaccaggag gacaagcagg tggttcaatg gttgtaccac cggtgacgca aacacctcca
    51241 tcaacttccc aaagtccagg acaaaaggcg accgaagctg aaaagaaaaa gttacaagac
    51301 ttgattcgtc aattccaaga agccttgaac aaactagacg atgaaacaaa gactgttcca
    51361 gatggggcta aactcacagg agaagctgga aaagcctata atgagactag aacttatgcg
    51421 aaagaagttg ttgacaaaag caagaagctt ctatcacaga cagcagtgac aatggatgaa
    51481 ttggcaatgc aattaaccaa attgaacgat gccatgtcta aattgaaaga agctaaagcg
    51541 aaattggtac cagaggttaa accacagccg gaaaacccag agccaaaacc acaaccagag
    51601 ggtgagaaac caagcgtacc agatattaat caggagaaag aaaaagctaa acttgctata
    51661 gcaacataca tgagcaagat tttagatgat ataaagaaac atcatctgaa gaaagaaaaa
    51721 catcatcaga ttgttgctct tattaaggac cttgataaac ttaaaaagca agcactttct
    51781 gaaattgata atgtaaatac caaagtagaa attgagaata cagtccacaa ggtatttgca
    51841 gacatggata cggttgttac taaattccaa aaaggcttaa ttcagaacac accgcaagtt
    51901 ccagaagcac caaagagccc agaggtacca aaggttccag atacaccaaa ggctccggac
    51961 acaccgcagg ttccagaagc accaaaggct ccagacacac cgcaaattcc ggaagcacca
    52021 gctccagaaa ctccggctcc agctccagaa gctccaaaaa caggctggaa acaagaaaac
    52081 ggtatgtggt acttctacaa tactgatggt tcaatggcaa caggctggct agaatacaat
    52141 ggctcatggt actatctcaa cgctaatggt gctatggc
//
LOCUS       DAVIME010000007        49912 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVIME010000007 DAVIME010000000
VERSION     DAVIME010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.007"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            324..593
                     /gene="blpJ"
                     /locus_tag="VV588_000465"
     CDS             324..593
                     /gene="blpJ"
                     /locus_tag="VV588_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEU7082859.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGSGLTCLGGMVGDKLGLSW"
     gene            662..796
                     /locus_tag="VV588_000466"
     CDS             662..796
                     /locus_tag="VV588_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HEU7082860.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWEILPKQVLEEQQQEVFN
                     "
     gene            733..891
                     /locus_tag="VV588_000467"
     CDS             733..891
                     /locus_tag="VV588_000467"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082861.1"
                     /translation="MQLGDFAKAGVGGAAARGLQLGIKTGTWQGAATGAAGGAILGGV
                     AYAATCWW"
     gene            894..1013
                     /locus_tag="VV588_000468"
     CDS             894..1013
                     /locus_tag="VV588_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU7082862.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1310..1474
                     /locus_tag="VV588_000469"
     CDS             1310..1474
                     /locus_tag="VV588_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082863.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            1471..1875
                     /locus_tag="VV588_000470"
     CDS             1471..1875
                     /locus_tag="VV588_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU7082864.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            2078..2882
                     /locus_tag="VV588_000471"
     CDS             join(2078..2446,2448..2882)
                     /locus_tag="VV588_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU7082865.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGVHESNLLRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKELANYSGKKKFHAMKTQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTVEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            3032..3286
                     /gene="blpM"
                     /locus_tag="VV588_000472"
     CDS             3032..3286
                     /gene="blpM"
                     /locus_tag="VV588_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU7082866.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            3302..3505
                     /gene="blpN"
                     /locus_tag="VV588_000473"
     CDS             3302..3505
                     /gene="blpN"
                     /locus_tag="VV588_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU7082867.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            3749..3898
                     /gene="blpO"
                     /locus_tag="VV588_000474"
     CDS             3749..3898
                     /gene="blpO"
                     /locus_tag="VV588_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU7082868.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            4002..4121
                     /locus_tag="VV588_000475"
     CDS             4002..4121
                     /locus_tag="VV588_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU7082869.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            4907..5290
                     /locus_tag="VV588_000476"
     CDS             4907..5290
                     /locus_tag="VV588_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU7082870.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            5342..6031
                     /locus_tag="VV588_000477"
     CDS             5342..6031
                     /locus_tag="VV588_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7082871.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            6073..6306
                     /locus_tag="VV588_000478"
     CDS             6073..6306
                     /locus_tag="VV588_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082872.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFLGAGYVVGFWLLILNENQRAN"
     gene            6457..7068
                     /locus_tag="VV588_000479"
     CDS             6457..7068
                     /locus_tag="VV588_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7082873.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFVPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYKSWPLLYYL"
     gene            7229..8023
                     /locus_tag="VV588_000480"
     CDS             7229..8023
                     /locus_tag="VV588_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU7082874.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETVPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            8020..8655
                     /gene="trmB"
                     /locus_tag="VV588_000481"
     CDS             8020..8655
                     /gene="trmB"
                     /locus_tag="VV588_000481"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU7082875.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            8781..9260
                     /gene="rimP"
                     /locus_tag="VV588_000482"
     CDS             8781..9260
                     /gene="rimP"
                     /locus_tag="VV588_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU7082876.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            9304..10440
                     /gene="nusA"
                     /locus_tag="VV588_000483"
     CDS             9304..10440
                     /gene="nusA"
                     /locus_tag="VV588_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU7082877.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            10462..10755
                     /locus_tag="VV588_000484"
     CDS             10462..10755
                     /locus_tag="VV588_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU7082878.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            10748..11047
                     /locus_tag="VV588_000485"
     CDS             10748..11047
                     /locus_tag="VV588_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU7082879.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            11064..13856
                     /gene="infB"
                     /locus_tag="VV588_000486"
     CDS             11064..13856
                     /gene="infB"
                     /locus_tag="VV588_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU7082880.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            14107..14457
                     /gene="rbfA"
                     /locus_tag="VV588_000487"
     CDS             14107..14457
                     /gene="rbfA"
                     /locus_tag="VV588_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU7082881.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            14736..15515
                     /locus_tag="VV588_000488"
     CDS             14736..15515
                     /locus_tag="VV588_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082882.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQDPTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            15517..15699
                     /locus_tag="VV588_000489"
     CDS             15517..15699
                     /locus_tag="VV588_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082883.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(16042..16116)
                     /locus_tag="VV588_000490"
                     /pseudo
     CDS             complement(16042..16116)
                     /locus_tag="VV588_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            16147..16380
                     /locus_tag="VV588_000491"
     CDS             16147..16380
                     /locus_tag="VV588_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU7082884.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            16380..17714
                     /locus_tag="VV588_000492"
     CDS             16380..17714
                     /locus_tag="VV588_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU7082885.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            17724..17978
                     /locus_tag="VV588_000493"
     CDS             17724..17978
                     /locus_tag="VV588_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU7082886.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            18074..18469
                     /locus_tag="VV588_000494"
     CDS             18074..18469
                     /locus_tag="VV588_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU7082887.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            18882..19331
                     /locus_tag="VV588_000495"
                     /pseudo
     CDS             18882..19331
                     /locus_tag="VV588_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
     gene            19318..19875
                     /locus_tag="VV588_000496"
     CDS             19318..19875
                     /locus_tag="VV588_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7082888.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAACALIDLAFKELGLHKIELTCFGYNLQSQRVSEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            19877..20839
                     /locus_tag="VV588_000497"
     CDS             19877..20839
                     /locus_tag="VV588_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEU7082889.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            20851..23502
                     /locus_tag="VV588_000498"
     CDS             20851..23502
                     /locus_tag="VV588_000498"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU7082890.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWDEFADWYVELTKEVLYSDNEEDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELDRLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            23573..24328
                     /locus_tag="VV588_000499"
     CDS             23573..24328
                     /locus_tag="VV588_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU7082891.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSLEDLY"
     gene            24368..24511
                     /locus_tag="VV588_000500"
     CDS             24368..24511
                     /locus_tag="VV588_000500"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082892.1"
                     /translation="MTGQRLNELEINGIRLTKFKNGEIGIEFIWIDTENPPSDAIGWV
                     AKK"
     gene            24614..25599
                     /locus_tag="VV588_000501"
                     /pseudo
     CDS             24614..25599
                     /locus_tag="VV588_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
     gene            25702..27396
                     /locus_tag="VV588_000502"
                     /pseudo
     CDS             25702..27396
                     /locus_tag="VV588_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            27696..28535
                     /locus_tag="VV588_000503"
     CDS             27696..28535
                     /locus_tag="VV588_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU7082893.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELAYLMAHIRRLTK
                     NLD"
     gene            28553..30391
                     /locus_tag="VV588_000504"
     CDS             28553..30391
                     /locus_tag="VV588_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU7082894.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            30404..31819
                     /locus_tag="VV588_000505"
     CDS             30404..31819
                     /locus_tag="VV588_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU7082895.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            32301..33347
                     /gene="pheS"
                     /locus_tag="VV588_000506"
     CDS             32301..33347
                     /gene="pheS"
                     /locus_tag="VV588_000506"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU7082896.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            33347..33856
                     /locus_tag="VV588_000507"
     CDS             33347..33856
                     /locus_tag="VV588_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7082897.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            33933..36338
                     /locus_tag="VV588_000508"
     CDS             33933..36338
                     /locus_tag="VV588_000508"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU7082898.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIVSLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(36406..37407)
                     /locus_tag="VV588_000509"
     CDS             complement(36406..37407)
                     /locus_tag="VV588_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU7082899.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            37563..37978
                     /locus_tag="VV588_000510"
                     /pseudo
     CDS             37563..37978
                     /locus_tag="VV588_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            38104..38370
                     /locus_tag="VV588_000511"
     CDS             38104..38370
                     /locus_tag="VV588_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7082900.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            38631..40880
                     /gene="metE"
                     /locus_tag="VV588_000512"
     CDS             38631..40880
                     /gene="metE"
                     /locus_tag="VV588_000512"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU7082901.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEANRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            40944..41810
                     /gene="metF"
                     /locus_tag="VV588_000513"
     CDS             40944..41810
                     /gene="metF"
                     /locus_tag="VV588_000513"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU7082902.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            42369..44582
                     /gene="pnp"
                     /locus_tag="VV588_000514"
     CDS             42369..44582
                     /gene="pnp"
                     /locus_tag="VV588_000514"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU7082903.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDYKPKKEFTETPKDSE"
     gene            44598..45215
                     /gene="cysE"
                     /locus_tag="VV588_000515"
     CDS             44598..45215
                     /gene="cysE"
                     /locus_tag="VV588_000515"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU7082904.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            45227..46111
                     /locus_tag="VV588_000516"
     CDS             45227..46111
                     /locus_tag="VV588_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7082905.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            46193..47536
                     /locus_tag="VV588_000517"
     CDS             46193..47536
                     /locus_tag="VV588_000517"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU7082906.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            47529..47915
                     /locus_tag="VV588_000518"
     CDS             47529..47915
                     /locus_tag="VV588_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU7082907.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            47919..48803
                     /locus_tag="VV588_000519"
     CDS             47919..48803
                     /locus_tag="VV588_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU7082908.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            48940..49395
                     /locus_tag="VV588_000520"
     CDS             48940..49395
                     /locus_tag="VV588_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082909.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            49392..49538
                     /locus_tag="VV588_000521"
     CDS             49392..49538
                     /locus_tag="VV588_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082910.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            49681..49851
                     /locus_tag="VV588_000522"
                     /pseudo
     CDS             49681..49851
                     /locus_tag="VV588_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        15402 a         8743 c        11068 g        14699 t
ORIGIN      
        1 atcgttgatg ctttacttag ttgatggatt ggtaggaata aaaaacttaa ctataaacta
       61 ttatttacta atattttttg ctttctgcaa gttaataaat agtatagtaa aactttttat
      121 tgcaaggaga ataacgaaat taagatattt tagatactca agattattga aatcttagac
      181 taaaaatagg tactgctacc tttaagaaga tagtagacgt atatactttt ttaagaaaat
      241 caaaaagata ctataaaaaa tctatttgtt tattgaattt aagactttgg taacaaattg
      301 aaaataaaaa ggaggtattc atcatgaata caaaaatgtt gtcacagtta gaggttatgg
      361 atactgaaat gcttgcgaaa gttgaagggg ggtatagctc cactgattgt caaaatgcac
      421 tgattacagg agtcactacg ggaattataa ctggtggaac tggagcaggt ttggccactt
      481 taggagtagc tggacttgct ggtgcatttg ttggagcaca cattggtgca attgggagtg
      541 gattaacatg cttaggaggt atggttggtg ataaattggg actaagttgg taagacttat
      601 agtaaaatta tgaggattct attctgattt attttagttt tttaaaaaag gagtatttgt
      661 catggataca aaaatgatgt cacaattttc tgttatggat actgaaatgc ttgcttgcgt
      721 tgaaggtggc ggatgcaatt gggagatttt gccaaagcag gtgttggagg agcagcagca
      781 agaggtcttc aactaggcat taaaacagga acatggcaag gtgcagcaac tggtgctgcg
      841 ggtggagcta tacttggagg tgtagcctat gcagcaacat gttggtggta attatggatt
      901 ttaaaagttt tattattggt ttagtagttg gtatatttgg tccttatatg gataatttaa
      961 ttagaaaaat attttcaaaa tttcccaaaa aggatacaga tagtaccccc taaaaaataa
     1021 atttctcccc tgtatttgct agcttaattt acaggggagt ttctttaatt ttgtttcgcc
     1081 tgtcaaaatg atatgtgata gcaggatgaa aagtctacaa acaagttggt atcaatacaa
     1141 tataaagagg aaagtatgtt tttcatgctt gcttttttaa tttttacaat tcaagaggtt
     1201 ttgatgacca tttatgattt gagtgatcca aggtcaaaat aagtgctata ctagcagtgt
     1261 aaatgttctt gctcaactaa gataaatcgc acatttagga ggaaatctta tgaagaaaaa
     1321 aatactgatt attttcgttc tgtatctaat catgtccatc tttctatatc cgcttaggga
     1381 gagtgcttgg tatcagctat tttataccat agcctatgtg attgcagtta tgatctattt
     1441 tgctatcaat aaaaagaaag gagaaaagaa atgaaaactt ttcttgctaa aaaacggaac
     1501 atcttccttg cgagattgtt cttaggtcag ttgcccttgc ttgtttctac ttatctattt
     1561 ctatctcgtc agtttttaaa tttttccgta gttttccaat ttcttttagt agttattaac
     1621 ttggcttcta ttttggttac tgtttatctc actagggaaa tgaggataag agagtttgaa
     1681 gatgatgatt tggttagtcc tagaaccaat caacttatgt tcatcggctt gacaggtttt
     1741 atgtctatta tttgtttgta tagaggtatc acagcaggag aatcctacca acaaataatc
     1801 gcttatattg gcgctgttct ctgcttaatc atcatgcttc tgctcatgtg gggcttgaag
     1861 tattataaaa agtagagctt aatgaagtat aaaagaaaag ggtaagtgtt tttgcaatac
     1921 ttaccctttt ataatagatt ccctgcgaaa caaaatatgg tatagtatag tagattgaaa
     1981 ctagaatagt acgcctctat ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
     2041 gatttatcct gttcttattt cattttacta tagttctatg aattatgaag caagtaaaca
     2101 actaaccgat gcacgattta agcgtcttgt tggtgttcag cgtaccactt ttgaagagat
     2161 gttagctgta ttaaaaacag cttatcaact taaacacgca aaaggtggac gaaaacctaa
     2221 attaagccta gaagaccttc ttatggccac tcttcaatat gtgcgagaat accgcactta
     2281 tgaagaaatt gcggctgatt ttggtgttca cgaaagcaac ttactccgtc ggagccaatg
     2341 ggttgaagta actcttgttc aaagtggtgt tacgatttca agaactcctc tcagttctga
     2401 ggacacggta atgattgatg cgacggaagt aaaaatcaat cgccctaaaa aaagaattag
     2461 cgaattattc tggtaaaaag aaatttcacg ctatgaagac tcaagcgatt gtcacaagtc
     2521 aagggagaat tgtttctttg gatatcactg tgaactattg tcatgatatg aagttgttca
     2581 aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt ggctgacagt ggttatcaag
     2641 ggctcatgaa gatatatcct caagcacaaa cttcacgtaa atccagcaaa ctcaaaccgc
     2701 taacagttga agataaagcc tgtaaccatg cgctatctaa ggagagaagc aaggttgaga
     2761 acatctttgc caaagtaaaa acgtttaaaa tgttttcaac aacctatcga aatcatcgta
     2821 aacgcttcgg attacgaatg aatttgattg ctggtattat caatcatgaa ctaggattct
     2881 agttttgcag gaagtctaat gtaatttttg caattcaaga cgtttcgatg actattcaag
     2941 atctggatga aaaattttaa aaaacgatga tatactaaac ttgtcaaagt tacaacaaga
     3001 caaaaattaa aaataaaaaa gagtatttgt catggataca aaaattatgg aacaatttca
     3061 tgaaatggat ataactatgt tatctagtat tgaaggaggc aagaataatt ggcaaactaa
     3121 tgtcttagaa ggtggtggtg ctgcttttgg tggctggggg ctagggacag ctatttgtgc
     3181 tgcgagtggt gttggagcac catttatggg agcatgtgga tacataggag ctaaatttgg
     3241 tgtggatctt tgggcaggag taacaggggc aacgggtgga ttttaataaa aggagacttg
     3301 tatgaatact tattgtaata taaatgaaac aatgctgagt gaggtttatg gaggtaattc
     3361 cggaggagca gctgtagttg ctgctttagg ttgtgcagcg ggtggagtga aatatgggag
     3421 acttctagga ccatggggcg ctgcaatagg aggaattgga ggagcagtgg tttgtggata
     3481 tttagcctat accgctacat cataaaaatg aaagctaaat tttatgaagg ctatattctt
     3541 tattattctc ttcgcttttc aaacctatct tatttatcta tccataagta tctccgataa
     3601 aaaacaaaag actattgaat taacatcatt gaattgtttt gtcatattat ttctaatcta
     3661 tgataaatta atttttctct ttattgccta tgtttttttg ataattttta tattaaactt
     3721 gttccgtaac tgaaaagtga tatactatat ggatacaaaa atgatgtcac aatttgcagt
     3781 tatggataat gaaatgcttg cttgcgttga aggtggagat attgattggg gaagaaaaat
     3841 tagttgtgca gcaggggttg catatggcgc aattgatggg tgtgcaacaa cggtttgaca
     3901 tttctattgg gaccatttgc tataggaata ggtgtaactg gtgctgcggg aggagctata
     3961 cttggaggtg tggcctatgc agcgacatgt tggtggtaat tatggatttt aaaagtttta
     4021 ttattggttt agtagttggt atatttggtc cttatatgga tgacttaatt agaaaaatat
     4081 tttcaaaatc ttccaaaaag gatacggata gtactctcta aaaaataaat ttctcccctg
     4141 tatttgctag cttaatttac aggggagttt ctttaatatt gtttcgcctg tcaaaatgat
     4201 atgtgatagc aggatgaaaa gtctacaaac aagttggtat caatacaata taaagaggaa
     4261 agtatgtttt taatgcttac tttttaaatt ttttaacaat tcaagatgtt tcgatgacaa
     4321 ttcaagattt ggatgaaaaa ttttaaaaaa caatgatata ctaaacttgt caaagttgca
     4381 acgggtgctg ctacattatg ttaaaaatcg ctcttgattg ataagttgga tttgttagga
     4441 aaggagtaaa taattatgga taagaaaaag atagtttcga ctataatatg tatagtattt
     4501 cttgtagtgt cagtagataa tttttttaga gacttaaccc cgttactgtt cattttaaat
     4561 attattggcc tgtcttgctt ttcagtgcta acatacatta acataaaaga gatactctta
     4621 aatataagta aatgatgatt tggttagtcc tagaaccaat caacttatgt ttatcggctt
     4681 ggcagatttt atgtttgtca tttgtttgta tagaggtatt tcagaaacag aattctatca
     4741 acaactaatc gcttatatag gtgtattctc tgcttgttta tcacgcttct gctcatgtgg
     4801 ggcttgaagt attataaaaa gtagctttct atccttttct gacaggatat ttgagtagaa
     4861 ggctctatta aattgttagt gaaataaatg aatggaggta tttaatatga aatacagatt
     4921 attttttgtt attttcttga gtagtgtgtt ggatattctt ttagggacat ttttacaaat
     4981 ctctatcgta tctattgggt ggcttgttct ttacagtggt ttgtttgaag caggagtttt
     5041 ccttcttgct aataaagggg tggcggtaaa aatcaaggaa gtagatattc gaaatcgctt
     5101 taaatttatt tttggaaaaa ccttatggtt tcaaattctt ttgctcatct ttttgataat
     5161 caaactttat cttggtttgg atgcgaggtt gattttattc tatggacata ttttcattgt
     5221 ctttaatgcc ttaatgtatc tattatctag tagtcaggtt agccttaaaa aaaacaaact
     5281 gtcttcttaa tcttacagca gtagagcctg acaaggtgag gtcatagtag ggaggatttc
     5341 tatgaaaaag tatcaacttc tattcaaaat aagtgcagtc ttctcttact tatttttcgt
     5401 atttggtctt tctcagctga cgcttatcgt ccaaaactat tggcaatttt cttctcagat
     5461 aggcaattta ttctggattc aaaatatctt gagtttactt tttattggag tcatgattgt
     5521 ggttcttgtt aagacaggcc atggttatct cttccgcatt ccaagaaaaa aatggctttg
     5581 gtattcgatt ttgacagtat tagtggtagt gttacagatc tcttttaacg ttcagacagc
     5641 taaacatgtt cagtcaactg cggaaggttg ggctgtattg attggttata gtgggactaa
     5701 ctttgcagag ctaggtattt atatagccct gttctttctg gttccactga tggaagaatt
     5761 gatttataga ggattactgc aacatgcttt ctttaagcat tcgcgatttg gtcttgattt
     5821 gcttcttcct tctattttat ttgctctccc tcatttttca agcctgccta gtctgttaga
     5881 tatcttcgtc tttgcaacag ttggaatcat ctttgctggt ttgacccgct ataccaagag
     5941 catttatcca tcctatgcgg tgcatgtgat caataatatt gtagcgacct tcccgttttt
     6001 gctcactttt ctacataggg tcttggggta aaaaaacaaa aggcttgctt ttcagccata
     6061 gaggaggtca tcatgtataa acacttattt ttcctagatt ccaaaacttt agatcggttg
     6121 acaccctata ttctagtctt ggcttctgac accattgctt ttaatgtttt tgtgctaacc
     6181 tttgtatctg cggtggtttt taatttccta aattccatgc tagctttaat ggctatcttc
     6241 ttaggagctg gctatgtggt cggattttgg ttactaatac tcaatgaaaa tcaaagagca
     6301 aactaggaaa ctagccgcag gctgtacttg agtacggcaa ggcgacgttg acgtggtttg
     6361 aatttgattt tcgaagagta taaaatggtt tgttttggaa aggctagaac taaaggatga
     6421 cgtgtaggaa gtctgtttgt tgaggaggat aattttatgg agttttttga taaatttcat
     6481 gccttgtgtt ttggattttt agtactaata attgtcatta cagttcctta tacgattaac
     6541 catggggatt tttttcaaaa tgaatctgca ttgattattg taagtcttct tgtaacctcg
     6601 ctgagtgttg cttatgctag aaagtttgaa atgatttctt ttgggatgtt aagcaagaaa
     6661 caacttttgc ttttcattgc aatctttctt ctaagtgtgc ttgagacgct ggtttatatt
     6721 catttcttcg ctgtttcttc tggctcaggg gtccaacact tggcggaagt cagcagagga
     6781 atttccctgt ctttgatttt gactacctca gtttttgtcc ccatccagga ggaactcatt
     6841 ttcagaggac ttcttcaagg tgcggttttt gacaattctt ggttagggct tgtgctaact
     6901 tcctctctct tttctttcat gcatggacct tctaatgtcc cttcgtttat tttttatcta
     6961 cttgggggct tgttactggg ctttgcttat aaaaagagtc aaaacctatg ggtttctact
     7021 ctagtacata tgctttacaa aagttggcca ctcttatatt atttataaaa attatgaaaa
     7081 ggtaagcaga agacggtgct tacctttttc aagctataat gatacccaag ccaatccaga
     7141 ggcttttctt tgagaatcgg gttagagtgg ttgacgaata ggccaaaaac tagtagaata
     7201 gtaaggaaac tttatacgga ggaaagaaat ggatttgggt gataatgagc taacactgac
     7261 tcccatacct gggaaaagtg gcaaggctta tatgggtagc tatcctgatg ggaagcgcat
     7321 ctttgtaaaa atgaacacct ctccaatcct acctggtcta gctagagaac aaattgctcc
     7381 acaattatta tggagtcgtc gtttggcaga tgggcgtgat atgtgtgctc aagaatggtt
     7441 gacaggcaag atattgaccc cctatgatat gaatcgtaag caaatcgtca atattttaac
     7501 ccgtcttcat cgctcacgtc cgttgatgac acaattgagt cgtttgggct atgccatgga
     7561 aacacctgta gatttactac agtcttggca ggaaacggtt ccagatgctt tgcgtaaaaa
     7621 tcattttatc agtgaagtga tggctgattt acgtcagact attccaggat ttagagagga
     7681 ccatgcgacc attgtccatg gagatgtacg acatagtaat tggattgaga cagatagtgg
     7741 cttgatttat ttagtagatt gggattcggt tcgcttgacc gatcgcatgt ttgatgtggc
     7801 ccatatgctc tgccattata tttcagaaca tcagtggaag gaatggttga cctactacgg
     7861 ttacaagtac aatcaaacgg tattaagtaa attgtattgg tatggtcaat tgtcttattt
     7921 gagtcagatt tccaagtatt atatgaacca agatttagaa aatgtcaatc gggagattca
     7981 tggtttgcgt catttccgag acaagtatgg aaagagaaga tgagagttag aaatcgtaaa
     8041 ggggcaacag aattactaga ggcaaatccc cagtatgtgg tcctcaatcc cttggaagcc
     8101 aaggcaaaat ggcgggactt gtttggcaat gataatccca ttcatgtgga agttggaagt
     8161 ggaaagggtg cctttgtttc aggtatggcc aagcaaaacc ctgacatcaa ctatatcggg
     8221 attgatattc aaaagtctgt tttgagctac gctttggaca aggtgcttga agctggagtg
     8281 tctaacatca agctcttgtg ggtagatggt tctgacttga ctgactactt tgaagacggt
     8341 gagattgatc gcttgtatct gaacttttca gatccatggc cgaaaaaacg ccatgaaaag
     8401 cgtcgtttga cctacaagac ctttttggat accttcaaac gtatcttgcc tgaaaatgga
     8461 gaaattcatt tcaagacgga taaccgtggc ttgtttgagt acagtttagt gagcttttct
     8521 caatatggca tgaaactcaa tggtgtctgg ctagatttgc atgccagtga ttttgaaggc
     8581 aatgtcatga cagaatacga gcaaaaattc tcaaacaagg ggcaagttat ctaccgagtt
     8641 gaggcagaat tttaagagat agcctaaaat taggctgtac aagtgctttt gctttacata
     8701 agttggcaaa cgtgctatac tgatagtaag aatatgaaaa gtgaggcggg gaaatatctt
     8761 cgcctcttgc ttatgaggag gtggacgcaa tcgcaacaat cgtagaatta gtcagagaag
     8821 ttgtagaacc tgtcatagaa gctccttttg aactcgtgga tatcgagtat ggaaagattg
     8881 gcagtgacat gattctcagt atttttgtag ataaacccga aggaattacc ttgaacgaca
     8941 cggcagactt gacagaaatg atcagtcctg tcctagacac catcaagcca gatcccttcc
     9001 cagaacaata tttcctagaa attaccagtc caggtttgga acgtcctttg aaaaccaagg
     9061 atgccgtagc tggagcggtt ggaaaataca tccatgtcgg gctctaccaa gccatcgata
     9121 agcaaaaggt ctttgaagga actttgttgg ccttcgaaga ggacgagttg actatggaat
     9181 atatggacaa gacgcgtaag aaaaccgtcc aaattccata cagtttagta tcaaaagcac
     9241 gtttagcagt taaattatag aaaaagaaag gatagctttt gaggattcaa aagtgaagaa
     9301 aacatgagta aagaaatgct agaggccttc cgcattttgg aagaagacaa gggaatcaaa
     9361 aaagaagata tcatcgacgc agtagtagag tcgcttcgtt ccgcttatcg cagacgctat
     9421 ggtcagtcag acagcgtagc tattgacttc aacgaaaaaa caggtgactt tacagtttat
     9481 actgtccgtg aagttgttga tgaagtattt gatagccgtt tggaaatcag cttgaaagat
     9541 gctcttgcca ttaattcagc ttatgaactt ggagacaaaa tcaagtttga agaagcacca
     9601 gctgagtttg gtcgtgtagc agcccaatct gccaaacaaa ccatcatgga aaaaatgcgc
     9661 aagcaaacac gtgccatcac ttacaatact tacaaagaac atgagcaaga aatcatgtct
     9721 ggtacagtag aacgctttga caaccgcttt atctatgtca accttggtag tatcgaagcc
     9781 caattgtcaa aacaagacca aattcctgga gaagtttttg cttctcatga tcgtatcgaa
     9841 gtttatgttt acaaggttga agacaaccct cgtggtgtga acgtctttgt tagccgtagc
     9901 catccagaaa tgatcaaacg tttgatggag caagaaattc cagaagttta tgatggaact
     9961 gttgaaatca tgagcgtggc tcgtgaagca ggtgaccgta cgaaggttgc tgttcgtagc
    10021 cacaatccaa acgtggatgc tatcggtaca atcgttggac gtggtggtgc taatatcaag
    10081 aagattacta gcaaattcca cccagctcgt tacgatgcta aaaatgaccg catggtacca
    10141 atcgaagaaa atatcgatgt tatcgagtgg gtagcagatc cagctgaatt tatctacaat
    10201 gccatcgctc ctgctgaggt tgaccaagtt atctttgatg aaaacgacag caaacgtgcc
    10261 ttggtggttg ttccagataa caagctttct cttgccattg gtcgtcgtgg acaaaacgtg
    10321 cgcttggcgg ctcacttgac tggttaccgt atcgatatca agtctgctag cgaatttgaa
    10381 gccatggaag acgctgcttc agtagagttg gaagtagaaa acgatactgt agaagaataa
    10441 aagctgctag aggagggaaa gatgaaaaca agaaaaatcc ctttgcgcaa gtctgttgtg
    10501 tctaacgaag tgattgataa gcgtgatttg ctccgcattg tcaagaacaa ggaaggacaa
    10561 gtctttattg atcctacggg caaggccaat ggccgcggcg cttatatcaa actagacaat
    10621 gcagaagccc tagaggcgaa aaagaagaag gtctttaacc gcagctttag catggaagtg
    10681 gaagaaagct tttatgacga gttgatcgct tatgtggatc acaaagtgaa aagaagagag
    10741 ttgggacttg aataagcaaa agataagtaa tctcttgggg cttgctcagc gagcagggcg
    10801 catcatatcg ggtgaagaat tggtggtcaa ggccattcaa gacggcaagg ccaagttggt
    10861 ctttctagct catgatgctg gacccaatct gaccaagaag attcaagata aaagtcatta
    10921 ttatcaagta gaaattgtaa ccgtgttttc aacactggaa ttaagcatag cagtcgggaa
    10981 atcgagaaag gttttggctg taacagatgc tggatttaca aagaaaatga ggtctcttat
    11041 ggaatagaag aggaggacat gatttgtcta agaaaagatt gtacgaaatc gcaaaagaac
    11101 ttggaaaaga aagtaaagaa gttgtagcgc gtgcaaaaga gttaggcttg gatgtgaaaa
    11161 gccactcatc aagtgtggaa gaagctgtcg ctgcaaaaat tgctgccagc tttaagcctg
    11221 cagctgctcc gaaagtagaa gcaaaacctg cagcaccaaa agtaagtgca gaaaagaaag
    11281 ccgaaaaatc tgagccagct aaaccagctg tagctaagga agaggcaaaa ccggctgagc
    11341 cagttgctcc gaaaacagaa aaagtagcag tgaaaccgca aagtcgtaat ttcaaggctg
    11401 agcgtgaagc ccgtgctaaa gagcaggcag aacgacgcaa gcaaaataag ggcaataacc
    11461 gtgaccaaca acaaaacgga aaccgtcaga aaaacgacgg ccgtaatggt ggaaaacaag
    11521 gtcaaagcaa ccgcgacaat cgtcgcttta atgaccaagc taagaagcag caaggtcagc
    11581 aaaaacgtag aaatgagcgc cgtcagcaag aggataaacg ttcaaatcaa gcggctccac
    11641 gtattgactt taaagcccgt gcagcagccc taaaagcaga gcaaaatgca gagtacgctc
    11701 gttcaagtga ggaacgcttc aagcagtatc aggctgctaa agaagccttg gctcaagcta
    11761 acaaacgcaa ggaaccagag gaaatctttg aagaagcggc taagttagct gaacaagcac
    11821 agcaagttca agcagtggtt gaagtcgtcc ctgagaaaaa agaacctgca gtggatacac
    11881 gtcgtaaaaa acaagctcga ccagacaaaa atcgtgacga ttatgatcat gaagaagatg
    11941 gtcctagaaa acaacaaaag aatcgaagta gtcaaaatca agtgagaaat caaaagaata
    12001 gtaactggaa taacaacaaa aagaacaaaa aaggcaataa caagaacaac cgtaatcaga
    12061 ctccaaaacc tgttacggag cgtaaattcc atgaattgcc aacagaattt gaatatacag
    12121 atggtatgac cgttgcggaa atcgcaaaac gtatcaaacg tgaaccagct gaaatcgtta
    12181 agaaactttt catgatgggt gtcatggcca cacaaaacca atccttggat ggggaaacaa
    12241 ttgaactcct catggtggat tacggtatcg aagccaaaca aaaggttgaa gtggataatg
    12301 ctgacatcga acgtttcttt gtcgaagatg gttatctcaa tgaagatgaa ttggttgagc
    12361 gtccaccagt tgttactatc atgggacacg ttgaccacgg taaaacaacc cttttggata
    12421 ctcttcgtaa ctcacgtgtt gcgacaggtg aagcaggtgg tattactcag catatcggtg
    12481 cctaccaaat cgtggaaaat ggtaagaaga ttaccttcct tgatacacca ggacacgcgg
    12541 cctttacatc aatgcgtgcg cgtggtgctt ctgttaccga tattacgatc ttggtcgtag
    12601 cggcagatga cggggttatg cctcagacta ttgaagccat caaccactca aaagcagcta
    12661 acgttccaat catcgtagct attaacaaga ttgataaacc aggtgctaac ccagaacgcg
    12721 ttatcggtga attggcagag catggtgtga tgtcaaccgc ttggggtgga gattctgaat
    12781 ttgttgaaat ctcggctaaa ttcaaccaaa atatcgaaga attgttggaa acagtccttc
    12841 ttgtggctga aatccaagaa ctcaaagcag acccaacagt tcgtgcgatc ggtacggtta
    12901 tcgaagcgcg cttggataaa ggaaaaggtg cggtcgcaac ccttcttgta caacaaggta
    12961 ccttgaatgt tcaagaccca atcgttgtcg gaaatacctt cggtcgtgtc cgtgctatga
    13021 ccaacgacct tggtcgtcgt gttaaagttg ctggaccatc aacaccagtc tctatcacag
    13081 gtttgaacga agcaccgatg gcgggtgacc actttgccgt ttacgaggat gaaaaatctg
    13141 cgcgtgcagc aggtgaagag cgtgccaaac gtgccctcat gaaacaacgt caagctaccc
    13201 aacgtgttag ccttgaaaac ctctttgata cccttaaagc tggggaactc aaatctgtta
    13261 atgttatcat caaggccgat gtacaaggtt ctgttgaagc cctttctgcc tcacttcaaa
    13321 agattgacgt ggaaggtgtc aaagtgacta tcgtccactc agcggtcggt gctatcaacg
    13381 aatcagatgt gacccttgcc gaagcttcaa atgcctttat cgttggtttc aacgtacgcc
    13441 ctacaccaca agctcgtcaa caagcagaag ctgacgatgt ggaaatccgt cttcacagca
    13501 ttatctacaa ggttatcgaa gagatggaag aagctatgaa agggatgctt gatccagaat
    13561 ttgaagaaaa agttattggt gaagcggtta tccgtgaaac cttcaaggtg tctaaagtgg
    13621 gaactatcgg tggatttatg gttatcaacg gtaaggttgc ccgtgactct aaagtccgtg
    13681 ttatccgtga tggtgtcgtt atctatgatg gtgaactcgc aagcttgaaa cactataaag
    13741 acgacgttaa ggaagttaca aacggccgtg aaggtggatt gatgatcgac ggctacaatg
    13801 atattaagat ggatgatgtg attgaggcgt atgtcatgga agaaatcaag agataagatt
    13861 ttttgctcct ttcttaggtg gtgagggacg caagcaaacc gatggtttca ttgcttattt
    13921 ttgagcctag ggtctcaaaa ataccctgtg atgggactga taaatcagtt ccatcacttt
    13981 caccacggcg aaagaagcag atgacttcaa attgaacttc gtttcaattt aaactgaaaa
    14041 tcaagaagtt taaaatagct aggtctgctg gcctagcttt tggttcaaag tagagaaagg
    14101 aatatcatgg caaatcattt ccgtacagat cgtgtgggca tggaaatcaa gcgtgaagtc
    14161 aatgagattt tgcaaaagaa agtccgtgat ccacgtgtcc aaggtgtgac catcacagat
    14221 gttcagatgc tgggtgactt gtctgttgcc aaggtttatt acaccatttt gagtaacctt
    14281 gcttcggata accaaaaagc ccaaatcggg cttgaaaaag caactggtac catcaaacgt
    14341 gaacttggtc gcaatttgaa attgtacaaa atcccagatt tgaccttcgt caaagacgag
    14401 tccatcgagt atggaaacaa gattgacgag atgctacgca atctggataa gaactaaaga
    14461 agaggggttg cccctctttt ttggtggagg aaaataggtt gaatttgaaa tggaaaaata
    14521 ttcttttata atagattgaa actagaatag tacgcctcta cttctaaaac attgttagaa
    14581 atcgatttga ctgtcctgat cgatttgtcc tgttcttgtt tcattttact ataaaaaagg
    14641 ggttctgtat tttttaatgt tatctaatta gaaaatgctt tttttgtagg aaatataata
    14701 tgataaggtg caaaaaagaa ataaggagtt tgtatatggc tgaacaagac ttagctatgc
    14761 aagtattgca acaagtggtg aaactacctg ttgttaaggt tgatcgttcg aaatttttag
    14821 tggataagtt ttccaaagaa ttggatccaa aagatattcc taccttattg gaacaagacc
    14881 caacgactct tctatctcaa gaaatattag atcgtgtagc taatgcttgt attcgggaca
    14941 atgtattatt agcgagtggg acttctgttt tggcaggatt acctggaggg cttgctatgg
    15001 caattaccat tccagctgat gtggctcaat tttatgcttt ctctctgaaa ttggctcaag
    15061 aattaggtta tatttatggt tatgaggatc tttgggcttc acgcgaggag ttgagtgaag
    15121 atgctcaaaa taccctcttg ctttatctag gcgtaatgtt aggggtgaat ggaaccgctg
    15181 ctttgctacg tgctggtggt ataacaattg ccaaacaggt aatgaaaaca gtgcctaata
    15241 aagctttaac aaagacgctt tggtacccta ttttgaaaaa agtcttaaaa atatttggtg
    15301 tgaatcttac caagggaggg ctggccaaag gaatagggaa atttattcct atcttgggtg
    15361 gtatcatttc aggtggttta acctttgcaa ctatgaaacc aatgggggaa agcttgcaga
    15421 aagaattatc caagctagtc aactatagtg aagttcaata tcaagaagat gttgaaacaa
    15481 tccgaaaaga ggctgaaatc atcaaaggag agtaatatga atcctatcaa agcttttgct
    15541 aaaatttatg gtaattactt tttgaccgtg caaggtgtaa aagtgatgaa aacgataaag
    15601 aaagctgacc atgtcgttgt tggtctgggc aaacttttta ttgcagataa gctaatggat
    15661 acggctcggt ggctcattaa gccagaggag agagaatgaa atttttttgg tcttcttgct
    15721 attcttttta tcaaaccgat tattgggatt gtgaaattct tttggatgat catttctttt
    15781 gcagttcaat tgctgtttta caagatattg gattggttct ttaaacttat ctagatggta
    15841 atccaagttg cagagaacta gcaggaactc cactgctagt tttttattct ctttccatat
    15901 ggtataatat aagcagtaaa atcattttat actcttcgaa aatctcttca aaccacgtca
    15961 gcttcacctt gcagtatata tgttactgac ttcgtcagtt ctatccacaa cctcaaaacg
    16021 gtgttttgag ctgacttcgt cagttctatc tacaacctca aaacactgtt ttgagcaacc
    16081 tgcggctagc ttcctagttt gctctttgat tttcattgag tattagaaca tacaatggag
    16141 gtcgtcatgg acaatatcat cgatgtgtca attcctgttg cagaagtggt ggacaagcat
    16201 ccagaagtct tggaaattct agtggagttg ggttttaaac cccttgccaa tcccttaatg
    16261 cgcaatacag ttggtcgtaa agtatcactt aaacagggtt ctaagctagc aggaactcct
    16321 atggacaaga ttgtacgcac actggaagcg aatggctacg aagtgattgg attagactaa
    16381 tgacagatga acggattcat atcctacggg atattttgtt agaattgcac aatggcgcct
    16441 ctcctgagtc ggttcaagat cgctttgatg cgacctttac gggcgtgtca gccatcgaga
    16501 tttcccttat ggagcacgag ctgatgaact cggattcggg cgtcactttt gaagatgtta
    16561 tggaactctg tgatgtccat gccaatcttt ttaaaaatgc tatcaaaggt gtcgaagttt
    16621 cagatactga gcatccaggt cacccagttc gtgtcttcaa agaagaaaat ctggctctcc
    16681 gtgcggcctt gattcgcatt cgtagattgt tagataccta tgagtctatg gaagacgagg
    16741 aaatgctggc ggagatgcgt aagggtttgg tgcgtcagat gggacttgtg ggtcaatttg
    16801 acatccatta ccaacgtaag gaagaactct tctttcctat catggagcgc tatggacacg
    16861 attcacctcc caaagttatg tggggagtgg atgatcagat tagggaactc tttcaaacag
    16921 ctctaacgac agccaagtca ctaccagaag tgtcaattag cagtgtaaag gaagcttttg
    16981 aagcttttgc gacagagttt gaaagtatga ttttcaagga agagtccatc ctcctcatga
    17041 ttctccttga gtcttttact caggatgact ggcttcagat tgcggaggag agcgatgcct
    17101 atggctatgc catcatccgt ccgtcagaga aatgggtgcc agaacgacag agctttattg
    17161 aggaaaagat tgcagaggag cctgtacagc tagatacggc agaaggtcaa gttcaacaag
    17221 tcatagatac gccagaaggc cattttacca ttacctttac ccctaaggaa aaggaagctg
    17281 tgctggaccg ccatagtcaa caggcttttg gtaatggcta tctttcagtc gagcaggcca
    17341 atctcatcct caatcatctc cctatggaga ttacctttgt caataaagaa gatattttcc
    17401 agtattacaa tgacaatacg ccagctgatg agatgatttt caaacggacg ccgtcccaag
    17461 tcgggcgcaa tgtcgaactc tgccatccgc ctaagtactt ggacaaggtc aaaactatca
    17521 tgaaggggct tcgtgaggga agcaaagaca agtatgaaat gtggttcaag tctgagtcgc
    17581 gaggtaagtt tgtccacatc acctatgctg cagtacacga tgaagacgga gaattccaag
    17641 gagtgttgga gtatgttcag gatatccagc cctaccgtga gattgatacg gactattttc
    17701 gtggattaga ataaggagaa aaaatgagtt acgaacaaga atttatgaag gaatttgaag
    17761 cttgggtcaa tacccaaatc atgattaacg atatggcgca caaggaaagt caaaaagttt
    17821 acgaagaaga ccaggacgag cgtgccaaag atgccatgat tcgctacgag agtcgcttgg
    17881 atgcttatca gttcttgctt ggtaagtttg aaaacttcaa agcaggcaag ggattccatg
    17941 atttgccaga aggcttgttt ggtgagcgaa attattaaac gagaaagatt cttgattttt
    18001 cactaaaatc ttgatagaat gtttatgtta aatccttgtc agagcaggga ttttttattg
    18061 aaaggatttt atcatgtcaa agaaactcaa tcgtaaaaaa caattacgaa atggcctccg
    18121 tcgcgcaggt gccttttcaa gtactgtgac taaggttgta gatgagacaa aaaaagtcgt
    18181 gaagcgtgca gaacagtcag caagcgcagc tggtaaggct gtttctaaaa aagttgaaca
    18241 agcagtagaa gctaccaaag agcaagctca aaaagtagct aattctgtag aagattttgc
    18301 agcaaatttg ggtggacttc cacttgatcg tgccaagact ttctatgatg aaggaatcaa
    18361 gtctgcttca gatttcaaaa actggactga aaaagaactc cttgccttga aaggaatcgg
    18421 cccagctacc atcaagaaat tgaaagaaaa tggcatcaag ttcaagtaat ttttcttgag
    18481 ccttgcattt ccgaaaaaat cttgctacaa tagagccatt agaggtgttt tgaatcccac
    18541 attttacaga aagtggcggc gctgagaagt ccacaaatgt gtcaaaactg gttgctaatg
    18601 gatgaaaaat tgaaataaaa gtgtcttttt gctttaaaga cgagagttgc gggcaactgc
    18661 ccgaaattgg gtggtaccgc ggataaacac attcgtccct gtcatgtaga tggcagggct
    18721 tttcttttac gtcttagtca aagggggttg ttatgaagca atcttttaac acaagtaaac
    18781 tatattatgg ttttcctgtt tttattttag gatatcaaga ttagaatttt ggctataaca
    18841 tcacgacctg tagttcctct tatagtctag gagattgggt tgtgattgga gtcgttgcaa
    18901 gagagaatgc cgcagagcag atcaaacagt atcaaaaatt tactgtgaat atttctgatg
    18961 aaacttctat gcttgcgatg gagcaggctg gttttatcag tcatcaggag aaattggaac
    19021 gtttgggagt gcattatgaa atttctgaat gaactcagac tcctatttta gacgcctgtc
    19081 cacttgtttt agattgtcgg gtagatagga ttgttgagga agacggtatt tgccacatct
    19141 ttgccaagat tcttgagcga cttgttgttc cagaactcct ggatgaaaag ggacatttta
    19201 aaaatcaact gtttgcccca acctatttca tgggagatgg atatcagcgc gtttatcgct
    19261 atctggacaa gcgtgtagat atgaagggca gtttcatcaa aaaagcgagg aagaaggatg
    19321 gcaagaactg agctgccaga taaaatcgaa acagaacgtc tcgttttacg agtccgtact
    19381 gtggcggatg ctgaggatat ctttgactat gctagtttgc cagaggttgc ctatccagca
    19441 ggttttcctc cagtcaagac cttggaagat gagatttatt atctggagca cattcttccg
    19501 gagcgtaatc aaaaggaaaa tctcccagca ggctacggga ttgtcgtcaa aggaacggat
    19561 aagatcgttg gctctgtcga tttcaaccat cgccatgaag atgatgtgct ggaaatcggc
    19621 tataccttac acccagacta ttgggggcga ggttatgttc cagaagcagc gtgtgccttg
    19681 attgatctag cttttaaaga acttggtctt cacaagattg aactaacttg ctttggatat
    19741 aaccttcaaa gtcaacgagt ctcggaaaag cttggcttta ccctcgaagc tcgcataaga
    19801 gaccgaaagg atgttcaagg aaaccgctgt gacagtctga tatatggctt gctgaagagc
    19861 gagtgggagg aataagatga gcgatgtaaa agaggaagta agctctctat ctgagaagca
    19921 gttacgccaa attgatgttg agtatgctga attaaatgat agtgatatta tcgagcgatt
    19981 agcttattta gaaattaaca acaatgaaaa acgtattgtc atctctgata ttgaaccaac
    20041 caaggaaata atgtcagtat cggaccaaat ttttgagatt caaaagaatt ttcaaaaaat
    20101 caagaatatg ttcgaattgt ttatttcaga tgtctcggat tttttaagta ttaaaaataa
    20161 acttgagtca aaggaattag aaattgaaga ggcagatgta aatcgtttca tgattcattt
    20221 attatccagt ggaaaattgt ttgtcgattt taacgaaaac caaattaaac aaaaatattc
    20281 caaagatagt gaggagtttg attgtataca tggttttgca agctatcagt atgataccaa
    20341 ttttgcttat cgattttgcc attctttgag aaattattcg caacatactg acttaccaat
    20401 aaatgaggta aaagctgtta gcccagatga tgagactgtt ataatagatt tctatattga
    20461 tttagattat cttttaaatt ccaactttaa atggaaaaaa ttgaaagggg agttgataaa
    20521 actaaaccaa gaaacatcta agattgacgc tatagctcta gtgaaagaat actttaatgc
    20581 tcttacagag ctctatggta attataataa gttgttttta aagttaaacc ataatacatt
    20641 agtagatatt aaatcaaagt tggaatcatt aaaattgaaa cactctaggt attatatttc
    20701 aaagataagc aagtatgatc ttaaatataa tcctggaaat tatactatgt caccacttgc
    20761 agcatttgct gaaattgaag agatttatat tgaactttca aaaattggtt tggttaaaat
    20821 tgtcaataaa agtaattaag gagaacacac atgtctaaag aactttcatc taaatacaat
    20881 ccagccgagg ttgaggctgg tcgttaccaa aaatggcttg atgccgatgt tttcaagcct
    20941 tcaggcgatc aaaaggctaa gccttattca atcgttattc caccaccaaa cgttacaggt
    21001 aaacttcacc ttggtcacgc ttgggataca actttgcaag atattatcat ccgtcaaaaa
    21061 cgcatgcaag gttttgatac cctttggctt cctgggatgg accacgcagg gattgccact
    21121 caggctaagg ttgaggagcg cttgcgtggt gagggcattt cccgctatga ccttggtcgt
    21181 gagtctttct tgacgaaagt ctgggaatgg aaagacgaat atgccactac catcaaggaa
    21241 caatggggca agatggggct ctctgtagac tattctcgtg agcgtttcac tcttgacgaa
    21301 ggtttgtcaa aagctgttcg taaggtcttt gtgaaccttt acaagaaagg ctggatctac
    21361 cgtggtgagt ttatcatcaa ctgggaccca gcagctcgca cagccctttc tgatattgag
    21421 gtgattcaca aggatgtgga aggtgccttc taccacatga attacatgct ggaagatggt
    21481 tcacgcgccc ttgaagttgc tacaactcgt cctgagacta tgtttgggga cgttgcggtt
    21541 gcggttaatc cagaagaccc gcgctacaag gacttgattg gtaaaaacgt catccttcca
    21601 atcgctaata aactcatccc aatcgttgga gatgagcacg cagatcctga gtttggtact
    21661 ggtgtcgtga aaatcacacc tgcccacgat ccaaatgact tcttggttgg ccaacgtcat
    21721 aacttgccac aagtcaacgt catgaacgac gacggaacta tgaatgagct tgcctttgaa
    21781 ttttcaggca tggatcgttt tgaagctcgt aaggcagtcg ttgctaagtt ggaagaaatc
    21841 ggtgcccttg tcaaaatcga aaaacgtgtc cacagtgttg gtcactcaga acgtacaggt
    21901 gtcgtagttg agccacgctt gtctactcaa tggttcgtca agatggacca attggctaag
    21961 aacgccattg ccaaccaaga cacagaggac aaggtcgaat tctacccacc tcgtttcaac
    22021 gataccttcc ttcaatggat ggaaaatgtc cacgactggg ttatctctcg tcagctttgg
    22081 tggggtcacc aaatccctgc ctggtacaat gctgatggtg aaatgtatgt cggcgaagaa
    22141 gctccagaag gtgacggatg gactcaggac gaagacgtct tggatacttg gttcagttct
    22201 gccctctggc cattttcaac catgggctgg cctgaagtcg actcagaaga ctttaaacgt
    22261 tatttcccaa cttcaacctt ggtaacaggt tacgacatca tcttcttctg ggtgtctcgt
    22321 atgatcttcc agtcattgga attcacaggc cgtcaaccat tccaaaacgt ccttatccac
    22381 ggtcttattc gtgacgagca aggacgcaag atgtctaagt ctctcggtaa cgggattgac
    22441 ccaatggatg ttatcgagaa atacggtgcc gatgcccttc gatggttcct ttcaaacggt
    22501 tctgcgccag gacaagacgt gcgtttctct tatgagaaaa tggatgcttc atggaacttt
    22561 attaacaaga tttggaacat ttctcgctat atcctcatga acaatggagg tttgacgctg
    22621 gatgtggcgc atgacaatgt cacaaaagtt gcaacaggtg aggctggtaa tgtgacggac
    22681 cgctggattc tccacaacct caatgaaacg attggaaaag caactgctaa ctttgataag
    22741 tttgagtttg gtgttgctgg ccacatcctc tacaacttca tctgggatga atttgcggac
    22801 tggtatgttg agttgaccaa ggaagtcctt tatagcgata atgaagaaga taaggtaatt
    22861 actcgatctg ttctccttta cactctggac aagatccttc gtctccttca cccaatcatg
    22921 ccattcgtga cagaggaaat ctttggacaa atctcagaag gttctatcgt gacagctgca
    22981 tacccaactg ttaatctagc ctttgaagac cttgcggctc acactggtgt agaaagtctc
    23041 aaagacttga tccgtgccgt tcgtaatgcg cgtgcggaag taaatgtagc accaagcaaa
    23101 cctattacaa tccttgttaa gactagcgat agtgacttgg aagccttctt taacagcaat
    23161 gtcaactaca tcaaacgctt tacaaatcca gaacatttgg aaatcgcatc aaccatccct
    23221 gcacctgaac tggctatgtc aagtgtcatc acaggagcag aaatctacct gccactggcc
    23281 gatctcctca atgttgaaga agaactagat cgtctcgaca aagaactcgc taaatggcaa
    23341 aaagaactgg acatggttgg taagaaactc tctaacgaac gcttcgtagc caacgccaaa
    23401 ccagaagtcg tccaaaaaga acgcgacaaa caagctgact accaagccaa gtatgatgcg
    23461 accgtagcac gtattgatga gatgaagaaa ctcgttaaat aaacacagaa acacggtgat
    23521 gagccgtgtt tttttggtat aatgaaatca atatctattg atggagaaag tgatgtccaa
    23581 acaccctcat tatgaattgt taaatttaat tggctacggt cttgccaagt ttgacaagct
    23641 ttttataaaa gaatttcaat gctctagcaa gtcggagttt tatcgttatg tggtttctct
    23701 gggaattgct gaaacaactg gagttgtaaa aaatagaatg gatttatttg atccttattt
    23761 tgacaataat cgaaaaggtt ggtggcagaa agctgaagtt tatcgttttc gtaaagattt
    23821 aattgatatg atgtttggaa atgaagatgt tcatagttat gctgaaatag ttaaaatgtt
    23881 acttgccagt gaagggaaga aaacaggcat aaccatcgtt gaaaaaccaa tagttcgaac
    23941 taaattcaaa cgtctacagg aaacgggaat ggaggctgag aattatttta tccttcattt
    24001 tgataaagaa gaaaaattcc aaggtggaca gttaaccgat gcccgtcttt atggtgatgg
    24061 atatgacttt caggtagatg tccaagagta ttcttacctt gccgaagtaa aaggtatccg
    24121 aaaatctaag gggcgtgtgc gtttaactgc aaaagaattt gaaaaagtca aggagtttca
    24181 atcggatttt attttatcct tggtcacaaa tctagatgat attccaaagt tagtgttaat
    24241 cgataatcct ttaaaacatt ttgagtttaa aaagaatatt atcaaaaatg aaatcattga
    24301 atatagaagc ttagaagatt tgtattagtt ccccccttaa cttttccagt tgaaagaacg
    24361 agaagtcttg acaggtcaac gactcaatga actggaaatc aacggtattc gtttaactaa
    24421 atttaaaaat ggggaaatcg gtattgaatt tatctggatt gataccgaaa atcccccaag
    24481 cgatgccatc ggctgggtag caaagaaata aaagttttca aaggtattgt aacaaataag
    24541 ggattttatt ttcgtgtaca atttcagcta ttcttgttat aatcagccta taggaatcaa
    24601 ggaggtgact cttatggctg tttttgtgtc tttggatgga attgtggtag aagtacttga
    24661 tgtcttttct tcttttgatg gggatagtga gtttttcttg tgtaaacgtc ttaaagacaa
    24721 gagtcagttt gttatggaac gctctcagtt cgaggagatg ttccaacttc aaagtagtcg
    24781 cttgacgacg caagaaaaat tacaattgtt tacctctgtg tttgctggcc gttatgatgt
    24841 ttatgctaag agttttatca atgatcaagg gaaaattcag tattttcctt cctatgatta
    24901 tggttggaag cagttgctac ctgaaaaacg gagtttccag acattgacgg attccgtttt
    24961 gaaatctcat tttcgtgggg aggcagctat cggtatcttt cctatgcact tagatgatag
    25021 ctgttatttt ttggtactgg atttggatga aggagattgg aaagaagctg gtttaaccat
    25081 tcgaagaata gccagggaac gccagatgga agcccattta gagatttctc gttcgggtta
    25141 cggactccat atttggttct tctttgagga agcgattctg agtcgaaagg ctcgcctgtt
    25201 tggaaagaaa ctattagaat tggcaatgca ggaaagtatg caactgtcct ttgattcttt
    25261 tgatcgcatg tttccaaatc aggatgtcct tcctaagggg ggatttggaa atttgattgc
    25321 cttgcctttt caaggagaag cttaccatca agggcgaacg gtctttgtgg atgaacagtt
    25381 tcagccttat gaagaccaat ggaggtatct acaagaaatt cagaggattt caactgctaa
    25441 agtggcactg ttaatccaag aggagttagg caagcaagaa ttggataagg agttgaaggt
    25501 cgttttatcc aatatgatcc aacttgaaaa atcgtctgtg acatccaagg cacttttttc
    25561 ttgaaaaata tggcttcctt ttctaatccc gaattttata gtagattgaa actagaatag
    25621 tacacctctg cttctaaaac attgttagaa atcgatttga ctttcctgat cgatttgtcc
    25681 tgttattatt tcattttact atatttaaag caggctatgc gacagccaac ctatcaaatt
    25741 cctgagagaa tgtatttatt tggagaatcc gatcattatt tatggttgcc aagaggtttg
    25801 ctgtatccat tgcaagataa atttaagcag gtatctgtgg aagataggag aaaggtacaa
    25861 aggtctatta gcgtggaatt taagggagaa ctcacttttg agcaagagtt agccctgtca
    25921 gatatgactt ctaaagaaaa tggtttactt catgcggaga ctggttttgg gaagaccgtt
    25981 ttaggtgctg ctcttatctc tgaacggaaa acaaaaacaa ttattctagt ccataataag
    26041 caactcttag accaatggct agatcgctta aactgctttt tgactttcga agaggaggag
    26101 gctatccgtt atacggcatc aggtcgtgaa aaggtaatcg gctatgttgg gcagtacggt
    26161 gggactaaga aatggctgag taaactggtt gatgtcgtta tgattcaatc tctatttaag
    26221 ttggaaaata gtcaaagtct tttggatgag tatgagatga tgattgtgga tgagtgtcat
    26281 catgtctctg ccttgatgtt tgaaaaagtt gttgctcagt ttagagggaa gtatctttac
    26341 ggtttgacgg ctacgcctga gcgtaagaat ggtcatgagc ctattgtttt tcagagaatt
    26401 ggtgagatac tccatactgc tgataagagg gaaacggatt ttaaacggca attgcaatta
    26461 agattcactt cttttggtca tttggaaatt gaaaagacca aagcaagtaa ttttatacag
    26521 cttagtgatt ggattgctac tgactcagtg aggaatcaga tgattctcaa ggatattcta
    26581 gcccaagtgg cagaaggacg gaatatcttg gttttagtta atcgaattca acagatagat
    26641 gtctttgaaa aattattgaa agagaaagag gttgatgact gttacattat tagcggaaaa
    26701 accaaagtcc gagagagaac gagtttactg gagacgttag aacagttaga taaagggttt
    26761 gttttgttgt ctactggaaa atacattggc gaaggttttg acttacctca gttggacacg
    26821 cttatcttgg cagcaccctt ttcttggaaa aataatttga ttcagtatgc aggttggatt
    26881 catagaaact acaaggataa gtctttggtg cgtattttcg attatgtgga tattcatgtt
    26941 ccttatttag aaaagatgtt tcagaaacga caagtagctt atcgaaagat ggattatcgt
    27001 gccattgagg gtgaggagaa acaattcgtt tatgttgata gtagatatga gaaggtgttg
    27061 agagaggact tagcagggga aagacaggaa tgtctgctta ttttacctta tgtgcaccag
    27121 acaaaactga tgaattttct aaaagaattt aggattagtc aaattgagat atgtatacca
    27181 gagacggttg caaataaagc atggctagac cagttgaaga gccagaaaat taaagtgtct
    27241 tttactcaat caaaaatagt aacgcctatt cttttggtga ataagactat tgtttggtat
    27301 ggtgcaatgc cattattagg gaaggtagat gagatgacca tattacgttt ggaatcagct
    27361 agtatagttt ctgaactagt ggcaggttta cgatagagaa aatttttaaa aatttctatg
    27421 tatgattttc atttctttag tgagactgtt gccattatca cattcgaatc acacaaaata
    27481 aaaaaatttt tataagtact tgacaaatag attgaaatat cataaaataa aaacggttac
    27541 agagttatta attatttaag cttcatgtca ccattaaaaa ttgaaataaa aggatgttat
    27601 cactaataca agtgagcagg aacctattta atcacatcag aagaagtttc ttgatgtttt
    27661 taagtaggtt ccttttattt taaaagggaa attttatgat cataaaacga atactaaacc
    27721 acaatgccgt aattgcgcaa agtaaaaaag atatcgatat tcttcttttt ggaaggggaa
    27781 tagcttttgg aagaaaaact ggagataaag taaatccaat tgatattgag aaaagttttt
    27841 ttctcaaaaa tagagataat atgacccgtt ttacagagat gtttattaac gttcctttgg
    27901 agttggtgta catcaccgaa aaaataatta acctaggtaa aataacattg ggtaataatt
    27961 ttgatgaaat tatctatatt aatttaacgg atcatatttc ttcgagcata gaacgttata
    28021 aagaagggat tattatttcg aatcccctac gctgggaaat atcgaaatat tataaagaag
    28081 aatttgaact tgggaaaagg gctttacaaa taataaaaaa agagttaggt attgaacttc
    28141 caattgacga agctgcattc atagcgctac attttgttaa tgctaattta gaaaataatt
    28201 ttcaagagtc gtataaaatc actgaaataa ttatgggaat tgagaaaatc attcaagatt
    28261 tctattgtac tgagtttaac caagattcta ttgattatta tagattcata actcatataa
    28321 aattatttgc ccatcgcttg gttgaaaata caacttattg tgacgatgat gatgaagact
    28381 tgttagcatt aatgaaaaat aaatatccta gagaatatga atgtggtgaa caggtagcaa
    28441 tgtttataca aacggagtac aattatttgc tgacttctag tgaattagct tatttgatgg
    28501 ctcatattcg tcgcttaaca aaaaatttag attaatagaa taggagaata ccatgagtta
    28561 taaagatacg gtacaaaaaa tcctcgatgt aattggaggt gaaaaaaatg tcaatagagt
    28621 tacccattgt gtaacacgtt taagattaga attaaaagat gaaaatttag tcaatgatga
    28681 tgatgtgaag aagataccag gtgtaatagg tattatgaaa aagaatggac aatatcaaat
    28741 tatacttggt aatgatgtag ctaattatta taaagaattc gttaaacttg gcaattttga
    28801 atccgattca gttgttcaag ggcacaaagg gaatatttta gaaagaatca ttgagtatat
    28861 cgctggttcc atgactccaa tcattccagc aatgttaggg ggaggtatgt tgaaagtctt
    28921 ggtaatcatt ttaccaatgc ttggtatatt gcaatcagat tctcagacta ttgctttttt
    28981 gacatttttt ggggatgctc catattattt cttaccgctg ttattagctt attctgcatc
    29041 acaaaaatta aaagtaacat ctacattagc tatgtctgta gcaggtgtac ttctccatcc
    29101 aaattttgtt caaatggtgc aatcagggaa tcctcttagt ttatttggtg cacctgtgac
    29161 accagctagt tatggttcat cagtcgttcc aattcttatt atggtttggt tgatgaaata
    29221 tattgaaaaa ataattgcta aattaacact agctattact aagagttttt tgcaacctac
    29281 gctagtatta ttagtatcaa gctgtattgc cttagttgta gtcggaccta ttggagtaat
    29341 tgttggtgaa ggattatcaa atctagttgg gcaaatgtat ggtgtagctg gatggcttac
    29401 attagctatt cttggtgcta ttatgccatt tattgttatg actggaatgc attgggcttt
    29461 tgcacctatt tttttggcgg catctattgc tactccagac gtattaattc ttccagcaat
    29521 gttagggtca aacttagctc aaggggctgc ttcgatggct gttgcattaa agagtaaaaa
    29581 taataataca aaacaaattg cttttgcagc aggtttctca gccttacttg cagggattac
    29641 cgaacctgca ttatatggtg tgactttaaa atataaaaaa ccgctttatg cagctatgat
    29701 tggtggtgga ttagcgggat tatttgcagg tcttactagt gttaaagcat atctatttgc
    29761 tgtcccatct ttgatagcgt tgcctcaatt tatttattct gatgtgccat caaatattgt
    29821 aaatgcttta attgtggcgg tcatttcggt tgttattacc tttgtattag cttatatatt
    29881 tggaatcgat gaagaagaga gttctagcaa tttagaagtt gaagctggag tttcaaataa
    29941 aaaaatgata ttttctccta tatcaggaga aatcattccg ttaagcgatg tccaggataa
    30001 aacattttca gataaactaa ttggagacgg agtagcgatt atcccaagtg aaggtaaggt
    30061 ttatgcacca tttgatggga aaattacaaa tatttttccg actaagcacg caattggatt
    30121 gaagagtgat gagggtgttg agttactaat tcatattgga ctagatactg ttgagctaaa
    30181 aggtcaaggt tttattagtc atgtagaaga aggagacaga gttttcaaaa atcagttgat
    30241 ttttgaaatg gacttgaatt taatcaagac taaaggctac gaaacagtta caccagtaat
    30301 tgtaacgaat accaatgatt ttctagatgt attagtatta cctaataatc agacaatcga
    30361 gcattctaag gaattactgg taatattata atggaggaaa gttatgacca tttttccaga
    30421 tgattttctt tggggtggag ctgttgcagc taatcaagta gagggagcat ataatgaaga
    30481 tggtaagggc ttatcagttc aggatgtgtt acccaaaggt ggattaggag aagcaacaga
    30541 aaatcctaca gaagataact taaaattgat aggtattgat ttttatcata aatataagga
    30601 agatatatcc ttgttttctg aaatgggctt taatgttttt cgtacttcta ttgcatggag
    30661 tagaattttt ccaaaaggag atgaggaaga acctaacgaa gctgggttga aatattatga
    30721 tgaattgttt gatgaactac atgctcacgg gatagaacca cttgtaactc tttcacacta
    30781 tgagactcca ttatatttag caagaaaata tcatggatgg gttgatagga gaatgattca
    30841 tttttatgaa aaatttgctc gaacagtttt agaaaggtat aaagataaag ttaaatattg
    30901 gcttacattt aacgaagtaa actctgtttt ggaattacca tttactagtg gaggaataga
    30961 tatacctaag gagaatcttt cgaaacaaga attatatcaa gctatacatc atgaattagt
    31021 cgcctcaagt ttggttacaa aaattgctcg tgagattaat tcagagttta aggtgggatg
    31081 tatggtatta gctatgccag cttatccaat gactccaaat ccaaaagatg tatgggcgac
    31141 tcatgagtat gagaatctaa attatctatt ttcagatgtg catgttagag gttattatcc
    31201 gaattatgca aaaagatatt ttaaggaaaa tgacattaac atagagtttg cagctgaaga
    31261 tgcagagtta ttaaaaaatt ataccgtaga ttttttatcc tttagctatt acatgagtgt
    31321 gactcaatct gctcttccaa cacagtataa ttcaggagaa gggaatatta ttggtggttt
    31381 agtaaatcct tatttagagt cttcagagtg gggatggcaa attgatccaa ttggactacg
    31441 tataatttta aatagatatt atgaccgtta tcaaatccca ttatttatag tagaaaatgg
    31501 attaggtgct aaagatcaac taataaaaga tgaacttaat aacttaaccg tccaagatga
    31561 ttatagaatt cagtatatga aagaacattt attgcaagtt gctgaagctc tacaggatgg
    31621 tgttgaaatt atgggctata cgtcttgggg atgtattgac tgtgtttcta tgtccactgc
    31681 acaactttct aaaaggtacg gtctcattta tgttgatcga aacgatgatg gaagtggtac
    31741 attaaatcga tataagaaaa tgtcttttac ttggtataaa gaagtgattg aatcaaatgg
    31801 agaatcctta ttcaaatagt tttttattga tgactagcta ttatcacggt taaggtggca
    31861 tttcattaaa tatggaataa agaagtttgg aagacattaa attctaaact tctttatttt
    31921 ataggggagt gtcaattaat ttaattttgt tacaaaaatt ataaatagtt aatttagata
    31981 aattgtttat ataaatttag ataagaataa gctaacaagc agaagtaaga taggtcttgc
    32041 aagaatggta aaaatctgat aaactaagta gtaattgaat aggaatctga aagactagta
    32101 gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat atgaaagctg
    32161 ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga tgaaaacgga
    32221 tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct ttttatctac
    32281 gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg cttcgcgaag
    32341 aaacgctggc tagcttgaag cagattactg ctggaaatga aaaagagatg caagatttgc
    32401 gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg atgaaagatg
    32461 tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt gatgtcttga
    32521 ctgctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg gctcaactgg
    32581 ctagcgagag tatagatgtg acgcttccag gtcgtccagt tgcgactggt caccgtcacg
    32641 ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt tatcaagtcg
    32701 tggatggttt tgaagtggag caagactact ataactttga acgtatgaac cttccaaaag
    32761 accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc ttgctccgta
    32821 cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct aaaggtcctt
    32881 tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg acccacagtc
    32941 accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg gctgatcttc
    33001 aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa attcgtttgc
    33061 gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct tgcttcaagt
    33121 gtggtggaga aggctgtaat gtatgtaaga aaacaggttg gatcgaaatt atgggggccg
    33181 gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta tactctggct
    33241 ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc aacgatatcc
    33301 gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga ttagaaaagt
    33361 agaaatggca gatgttgagg tgttggctaa aattgccaaa caaacctttc gtgaaacctt
    33421 tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt atagtctgaa
    33481 aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta tgcatgagga
    33541 ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga gagaattaga
    33601 ggacgctttt gaaattcaac gtctctatgt gctacaaaaa ttccaaggat ttggactagg
    33661 taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt cttgggcttg
    33721 gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataaccgat atggttttga
    33781 aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt ggttactgag
    33841 aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg aaaagaacta
    33901 gagtgacaac tgtcattctg gagaactaaa ttatgcttgt atcttataaa tggttaaaag
    33961 aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca actacaggga
    34021 tcgaggtaga gggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc gtcggtgagg
    34081 tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcagatt aacgttggcg
    34141 aagaagaaga gcgtcagatc gtttgtggtg ccccaaatgt gcgtgctggg atcaaggtca
    34201 tggtggctct tccaggagct cgtatcgctg ataactacaa aatcaaaaaa ggaaaaatcc
    34261 gtggtttgga gtcacttgga atgatctgtt cacttggtga attgggaatt tctgactcag
    34321 ttgtgcctaa ggaattcgca gatggcatcc aaatcttgcc tgaagatgcc gtgccaggtg
    34381 aggaagtctt ttcttaccta gacttggatg atgaaatcat cgaactttcc atcacaccaa
    34441 accgtgcaga tgccctttct atgtgtggag tggctcacga agtggcagcc atctatgaca
    34501 aggcagtcaa ctttaaaaaa tttactctaa cagaaactaa tgaagctgcg gcagatgccc
    34561 tttctgtcag cattgagaca gacaaggcgc cttactatgc agctcgtatc ttggacaatg
    34621 tgactatcgc accaagtcca caatggttgc aaaaccttct catgaacgaa ggcatccgtc
    34681 ccatcaataa cgttgtagac gtgacaaact acatcctgct ctactttggt caacctatgc
    34741 atgcttttga cttggacaca tttgaaggga ctgacatccg tgtgcgtgaa gcgcgtgatg
    34801 gtgaaaaatt agtgaccctg gacggtgaag aacgagactt ggctgagaca gacctcgtga
    34861 ttacagttgc tgacaaacca gtagcccttg ccggtgttat gggtggtcag gctacagaaa
    34921 tttctgaaaa atctagtcgt gttatccttg aagctgctgt ttttaatggc aaatctatcc
    34981 gtaagacaag tggtcgcctg aaccttcgtt ctgagtcatc ttctcgcttt gaaaaaggaa
    35041 ttaatgtggc aacagttaat gaagcccttg atgcggcagc tagcatgatt gcagagcttg
    35101 caggcgcgac ggtgcgtaag ggtatcgttt cagcgggtga gcttgatacc tctgatgtgg
    35161 aagtttcttc aacccttgct gatgttaacc gtgtcctcgg aactgagctg tcttatgctg
    35221 atgtagaaga cgtcttccgt cgtcttggct ttggtctttc tggaaatgca gacagcttta
    35281 cagtcagcgt accacgtcgt cgttgggata tcacaatcga agctgatctc tttgaagaaa
    35341 tcgctcgtat ctatggatat gaccgcttgc caaccagcct tccaaaagac gatggtacag
    35401 ctggtgaatt gactgtgata caaaaactcc gccgtcaagt tcgtaccatt gctgaaggag
    35461 caggtttgac agaaatcatc acctatgctc tgacaactcc tgaaaaagca gttgagttca
    35521 cagctcaacc aagtaacctt actgaactca tgtggccaat gactgtggat cgttcagtcc
    35581 tccgtcaaaa tatgatttca gggatccttg ataccgttgc ctacaacgtg gctcgtaaga
    35641 ataaaaactt ggccctttat gagattggaa aagtctttga acaaacaggt aatccaaaag
    35701 aagaacttcc aaatgagatc aacagctttg cctttgcctt gacaggcttg gttgctgaaa
    35761 aagatttcca aacagcagca gttccagttg atttcttcta tgctaaggga atccttgaag
    35821 ccctatttac tcgtttggga ctccaagtaa cctatacagc aacatctgaa atcgttagcc
    35881 ttcatccagg tcgtacagcc gtgatttcac tcggtgacca agttcttggt ttccttggcc
    35941 aagtgcatcc agtcactgcc aaggcttacg atattccaga aacgtatgta gctgagctta
    36001 acctttcagc catcgaaggg gcgctccaac ctgctgttcc atttgtggaa atcaccaaat
    36061 tcccagcagt cagccgtgac gttgcccttc tcctcaaggc agaagtgact caccaagaag
    36121 ttgtagatgc tatccaagct gccggcgtga aacgtttgac agatatcaaa ctctttgacg
    36181 tcttctcagg tgaaaaactg ggacttggta tgaagtcaat ggcttatagc ttgaccttcc
    36241 aaaatccaga agacagctta acggacgaag aagtcgcacg ctatatggaa aaaatccaag
    36301 cgtctctcga agaaaaagtg aatgcagaag tgcgttaaac gatagtagga tacaaattcc
    36361 ccctctagtt tatgaacatt agaggggtga ttttatataa aataattaaa atgtgatttc
    36421 tgtaaaaata catctatgat cagagttttg aaaacttaca atgtctaaat ctttaacata
    36481 gtagtggttt ttaggcaata aaatatgatc tattgttgca ttaaaaagtt ttggactttg
    36541 gctattccaa gttcctcttt caaaaggtgg cagtgcattt aatgcgtccc tatgagagct
    36601 tatttttgca agtgctccat gacgcatagt tgcattaaaa tcacctgcaa taatagcctt
    36661 tggatatttt gaagccaatt gattatgaat gatgtttaag tcttgcttcc agatttccat
    36721 taaacctggc agaggaggag cagtatgcaa ggcaatgata tctggtatat tttgttttct
    36781 cgaatgtaat acaattgtcc cgaaccgtgt tgtatgaaaa gttttagctt ctgtatagaa
    36841 accataactt ttcttgacaa tcacagtcac aggagctatt ccactattgg taggtggaga
    36901 agtgaaaata tcatagttgg ccatagaaag tccaacttga tgaaacaata gtttgattct
    36961 ctggttttct tgctcacctc tgatattggt agctagttca gggaatatag ccatatcggc
    37021 gtcaaaatgg ctaaaaattc gctcaatatg ttgtgcttct atttgattag cgacgttcca
    37081 agttactaat tttaaggttt tagtcttatt tgatgcagaa gaaagggttt tatctgttcc
    37141 gaataatagt aatatgagcg atagtaagag caaaatgcca gagtaaaacc gtatttgttt
    37201 atttttcttg taaaaagata ggaaaaaaaa taagaaactt aaaatagcag ccatagttgc
    37261 agtagctaag gggaaggcat aaatctgtgc caagataggt tgggtagata gccaaatgtt
    37321 aagattagaa gatgggaaaa aagaataagt tatgataggg atagaaaaga gaatgaccga
    37381 aagggcagag agaaatgttt taatcattgt gtgagtacct caatttgcaa tggttgctcg
    37441 gagctaatgt gactttgtga ctttacttga ttgatattct ttttcttgtc ttcctcatag
    37501 attaagtaca acccaagtaa aaaaagtcca atttaagatt gaaatgatta aaaggcacag
    37561 aaatgcaaga caattatact acaaaaggca aacatttgac aatcgatagc cgtcgcttaa
    37621 tcgaacgatg gaaaaaagaa ggaaaatcaa atagagaaat tgcctctcta cttggaaaag
    37681 ctcctcaaac tatccacact gaaatcaagc gtgggacagt ccgacaatgt cttggaaaag
    37741 ggcgcttcaa agagatttat tctgccgact acgctcaaca gtcttaagaa actaaaggaa
    37801 aagattctcc actatacata accaaaaaca taaccaaaaa ttttcgcctg aaatgatggt
    37861 gatggctaaa ggggttaacg tgggaatttc aaccatttac tattggattc atcgtggaaa
    37921 attggggtta agcaagcagg aactgcttta tcctagaaaa ggaaaatcgc ttaagaaata
    37981 ggctagcacc aactttaaac ccactggtca atctatcgaa tcataattcg ctcatttttt
    38041 taaaaataca tagacgtaaa aaaaagaggg ttaagtgatg aagaatagtg ctattgggag
    38101 taattggaag gatgtccatc tgagctcttt agcaaggagg aaatccttga aagtgatatg
    38161 cgagtggcta tcatgagcga gttgattgag gctaggtatg aacaaggaat cagtcagaaa
    38221 aagctggaag aagtcagtgg aataagccag cctgtcatag ctaggatgga gacaggaaag
    38281 actagtcctc agttggatac agtcttaaaa gtcctagcca gtttaggaaa gacactagca
    38341 atcgtcccac ttgaacaggg aaaaagttga ctagaatcag ttatagtctt ttctaataac
    38401 aggtcatagt cacttataag aattactaat aacatgtttt agtattctaa ttggaatata
    38461 gctgtaaagt aagaattaca aaggatttga gacgtttgct tcaagtcttt ttcttttgtc
    38521 cgaaacagat atatagtttc aaactatatc aaaccctaat tttttacaat tatacagacg
    38581 ctttcttttc tgttaagata gtttcaacaa caaattttgg aggacacatc atgtcaacta
    38641 caatcatcgg tttccctcgt ttgggcgaat tccgtgaatt aaaatttaca actgaaaaat
    38701 actttagaaa agaaatctca gaagaagaac ttttagcagc agcaaaagac ttgcgtgcta
    38761 aacactggaa cattgtcaaa gaaaaaggca tcactgaaat tccatcaaat gacttttctc
    38821 actatgataa cttcctagat gcggctttcc ttttcaacgt ggtgcctgca tccgttcaaa
    38881 acttggactt gtctgacctt gagcgctact tcgctttggg acgtggttac cagggagaaa
    38941 aaggggacgt tcgcgccctt ccaatgaaga aatggttcaa cactaactac cactacatcg
    39001 ttcctaaatt tgaaaaagac actcaagtaa aattggctgg tcacaagatt ttcgatgagt
    39061 tccaagaagc caaagaactt ggattgaaca ctcgtcctgt tcttgtaggt cccttcactt
    39121 tccttcaatt gtcagacttt gaagaaggcg tgaaagcaga cgacttcgta gatagcttag
    39181 tggctgctta ccaagaagtt tttgctaaat tggctgaact tggtgcgact cgcatccaat
    39241 tggatgaagc ggctcttgta aaagacttga cagctgaaga aaaagctctc ttcttgaacc
    39301 tttacaacaa actcttggct gacaaaaaag gtcttgaagt cttgcttcaa acttatttcg
    39361 gtgatgttcg tgacgtatac gctgaccttg taaacttacc agtagatgct atcggtcttg
    39421 actttgttga aggtaagaaa actcttgaac tcgttaaagg tggcttccca gctgacaaga
    39481 ctctctatgt aggtattgtc aatggtaaaa acatctggcg caacaactac gaaaagagct
    39541 tggctgttct tgagcaaatt ccagctgaaa acatcgtttt gacaagctct tgctcacttc
    39601 ttcatgtgcc atttacaact gctaatgaag aatttgaacc agcactcttg aaccactttg
    39661 cctttgcagt tgaaaaattg gatgaaatcc gtgacttgga tgctatccga aatggtcaag
    39721 gttcagaagc tcttgcagcc aacaaagaac tctttgcgac tgagcgtgtt ggtgaaaatg
    39781 ctgaacttcg tgcgcgtatc gctggcttga cagacgcaga ctacactcgt ttgccagcct
    39841 ttgcagaacg tgaagctatc caagaagaag ctttcaaact tccagctctt ccaacaacaa
    39901 cgattggttc attccctcaa acaaaagaag ttcgtgccaa acgtttggct taccgtaaag
    39961 gtgaattgtc tcaaaaagag tacgacgctt tccttgctga aacgattgac gaatggatca
    40021 agtggcaaga agatattgac tttgatgtcc ttgttcacgg tgaatttgag cgtaatgaca
    40081 tggttgagta cttcggtcaa aacttgtcag gatacctctt ctctaaaaat ggatgggtac
    40141 aatcatacgg tatgcgtggg gtaaaaccac caatcatctg gggtgatgtc actcgtctta
    40201 accctatcac tgttaaatgg tctagctatg cacaaagtcg tacaaacaaa cctgttaaag
    40261 gtatgttgac tggacctgtt accatcctta actggtcatt cccacgtgaa gacatctcta
    40321 tcaaggattc aactctccaa atcgcccttg ctatcaagga tgaagtactt gaccttgaag
    40381 ctgctggtgt gaaaatcatc caaatcgacg aggctgctct tcgtgaaaaa ttgccactcc
    40441 gccgtagcga ctggtacgaa gactaccttg actgggctat tcctgccttc cgcttggtac
    40501 actcaacagt agcgccagac acacaaatcc acactcacat gtgttactca gaatttacag
    40561 atatcatccc agctatcgat aacatggatg cagacgttat ttcctttgaa gctaaccgtt
    40621 caaaccttga aatcttggac gaactcaaag cgaaaaactt ccaaacagaa gtgggacctg
    40681 gggtttacga tatccactca cctcgtgtac caaatgaagg cgaaatcgac aacacaatcg
    40741 aagccatcct tgctaaagtg ccaagcaaga aagtttggat caaccctgac tgtggtttga
    40801 aaacacgtgg tatcccagaa acaaaagaaa gcttgatccg ccttgttgaa gcagctaaag
    40861 ctgcgcgtga gaaattgtaa gattggattt ctctccatac agtggttgtt caaaaagaaa
    40921 tcaactagaa aaggttatta catatgtcac gccaaacacc gtcactctca tttgaagtgt
    40981 tccctccaaa cccagccgtg ggtaatgata acattatttc agccttgcag gatatgcagg
    41041 agttggctcc ccattttatc agtgtaactg ccagcaataa taaatttaat atcaaggaaa
    41101 cgacggttcg tttggctgac tttatccaaa atgatttggc gattccgacc attgcccact
    41161 tgccagctat ttatctaact aaggacaagg ttgctgaaac tattgctgac ttggacaaag
    41221 ttggggtgca gaaaatcttg gctcttcgtg gggatattat tccagacgtg gaaccacaaa
    41281 aggatttccg ctatgcaacc gacttgattg agtttatcaa ggaacaaacc cctcactttg
    41341 atattattgg agcttgctat ccagaagggc atccagattc gccaaatcag atttcagata
    41401 ttcaaaatct taagaagaaa gtggatgcag gctgttcgag cctcgtaact cagctcttct
    41461 ttgacaatga gcgcttctat gattttcagg acaagtgtat cttggctggg attgatgttc
    41521 ccattcatgc aggaattatg ccaattctga atcgaaatca ggctctccga ctcttgaaga
    41581 cttgtgagaa tatccatctt ccacgcaaat ttaaagccat cttagacaag tatgagcatg
    41641 accctgagtc gctcagagca gcaggacttg cctatgcagt ggaccaaatc gtggacttgg
    41701 taactcagga tgttgccggt gtgcatctct atacgatgaa taatgctgat acagcaaaat
    41761 acatccatca agcaacccat gccttgttta atcaccagtc tctaggataa taaaagcaaa
    41821 ccattcttct caggtgaggg gaatggttcc tttttaatgg taaagacctc actttttaag
    41881 aaaaatatga taaaatagat tctgtacgta cttgatacaa agatgaaggt attaaataat
    41941 acaatgcatt taaactgtaa gatttaacga cacgagtgag tcaaatcgat gttatttgac
    42001 gaaagagtta gtaaagcatt tagctaatcg cccgatagcg attagcgtga aaggtttaga
    42061 tactttaata ttaaaccttt ctaatgatgt atcttgaaaa ctgaacacgc ctacaactct
    42121 gtggaaaaag ataaatctgc ctaggagcag tcgctccgtc gttcgatttc ctattttcct
    42181 ttgagttgct tgacggctta gcatcttgag taattgaaca cggccgaaaa gctgtgtaaa
    42241 aaagataaac tgtcttgtct tcatcgaaga cttcgtcagt ttcctatttt tactttgctt
    42301 ttgacgtcct tggtatcttg atctttgtag gcaaggcgta taatttcatc aatccaaagg
    42361 ggattaaaat ggcaaaacaa gtgtttcaaa cgacttttgc gggtcgtgag ttaattgtag
    42421 agactggtca ggttgctaag caagcaaatg gctctgttgt cgtacgttac ggtgagtcaa
    42481 ctgtcttgac tgctgccgtt atgtctaaga aaatggcaac tggggatttt ttcccactcc
    42541 aagtcaacta cgaagaaaaa atgtatgcgg ctgggaagtt tcctggtggc tttatgaaac
    42601 gtgaaggacg tccttcaaca gatgcgacct tgacagcgcg tttgattgac cgtccgattc
    42661 gtcctatgtt tgcggaaggt ttccgtaatg aagtccaagt catcaataca gtgctttctt
    42721 atgatgaaaa tgcatctgca ccaatggctg ctatgtttgg ttcatctttg gcactgtcta
    42781 tttcagatat tccatttgac ggaccaattg ctggggtaca agtgggatat gtagatggcc
    42841 aaatcatcat caacccaagt caagaacaag cagagcaatc tcttcttgaa ttgacagtag
    42901 ctggaaccaa gcacgctatc aacatggtag agtctggtgc caaagaattg tcagaagaaa
    42961 tcatgttgga agcgcttctt aaagggcacg aagctgtcaa agaattgatt gccttccaag
    43021 aagaaatcgt tgctgctgtc ggtaaagaaa aagcagaagt ggaattgctt cacgtggatg
    43081 ctgaattgca agctgaaatc attgcagcct acaacagtga cctccaaaag gcagttcaag
    43141 tagaagagaa attggcccgt gaagctgcaa ctcaagcagt gaaagaccaa gtgactgccg
    43201 tttacgaaga aaaatatgcg aaccacgaag aatttgaccg tattatgcgt gatgtggctg
    43261 aaatcttgga acaaatggaa cacgcagaag tgcgacgttt aattacagaa gacaaggtgc
    43321 gtcctgatgg tcgtaaggtc gatgaaatcc gtcctttgga tgcggttgtt gacttccttc
    43381 ctcgtgtaca tggttcaggt ctctttactc gtgggcaaac tcaagctctt tcagtcttga
    43441 ccttggctcc gatgggagaa actcaaatca ttgatggttt ggatccagag tacaagaaac
    43501 gctttatgca ccactataac ttccctcaat attctgtagg ggaaacaggt cgttacggtg
    43561 cgccaggtcg tcgtgaaatc ggtcacggtg cccttggtga gcgtgctctt gctcaagtct
    43621 tgccaagctt ggaagaattc ccatacgcta tccgtctagt agcagaagtt ttggaatcaa
    43681 acggttcttc atctcaagct tctatctgtg cgggaactct tgcccttatg gctggtggtg
    43741 tgccaatcaa ggcgccagta gctggtattg ctatgggact tatctcagat ggaaataact
    43801 acacagtatt gacagatatc caaggtttgg aagatcactt tggagatatg gacttcaagg
    43861 ttgcaggtac tcgtgatggg attacagccc ttcaaatgga tatcaagatt caagggatta
    43921 ctgcagaaat cttgacggag gctcttgctc aagccaagaa agcgcgtttt gaaatccttg
    43981 atgtcattga agcaaccatt ccagaagttc gtctagaatt ggctccaact gctccgaaaa
    44041 ttgatacgat caagattgat gtggacaaga ttaagattgt catcggtaag ggtggagaaa
    44101 ccatcgacaa gattatcgct gaaacaggtg ttaagattga tatagacgaa gaaggaaatg
    44161 tgtctatcta ctctagtgac caagatgcta ttaaccgtgc caaagaaatt attgctggtt
    44221 tggttcgtga agccaaagtg gatgaagttt accgtgctaa agtcgttcgt atcgagaaat
    44281 ttggtgcctt tgttaacctc tttgataaga cagatgccct tgttcatatc tctgagatgg
    44341 cttggactcg taccaatcgt gtagaggatt tggtagaaat cggggatgaa gttgatgtta
    44401 aggttatcaa gattgatgaa aaaggccgta tcgatgcctc tatgaaggct cttctacctc
    44461 gtccgccaaa acctgagcat gatgaaaaag gtgaaaagtc tgagcgccct caccgcccac
    44521 gtcatcacaa ggattacaaa cctaagaaag aatttacaga aacaccaaaa gattcagaat
    44581 aagaaaagga gaaatgtatg gggtggtggc gcgaaaccat tgatattgta aaagaaaatg
    44641 atccagcggc ccgcaccact ttggaggttt tgctgactta tccaggtgtc aaggccttgg
    44701 cggcccaccg tctctcgcat tttctctgga agcacggctt caaactatta gctcgtatgt
    44761 acagtcagtt ttggcgcttt tggactcaga ttgagattca tccaggagcc cagattgatt
    44821 caggtgtttt tattgaccat ggttctggtc tggtgattgg agagacagcg attgttgaaa
    44881 aaggcgttct tctctatcac ggagtgactc tcgggggaac agggaaagac tgtggcaaac
    44941 gccatccgac tgtacgaaag ggagccctca tatcagccca tgcccaagtt atcgggcctg
    45001 tggaaattgg tgaaaatgcc aaggtcggtg ctgcagcagt tgtcgtagca gatgtaccta
    45061 gtgacgtgac ggttgtcggt attccggcca agattgtccg tcttcatggt aagaaagatg
    45121 agcctgtcat tcacgaagtc gaagaaaaac gagagtatta tgtcaataaa ctcgagcagg
    45181 ctaaagatgc cagtcacaga tcgtctggtt tgtagaggat acctatatga ttcaagcaag
    45241 aaacaagtta agccaagagg agctatctga ggcgaaaaaa gtaattaact gttgccaaaa
    45301 ctatgacggt acctatcgcg atccctatct ctctaacatg cttaattttg acccaaacat
    45361 gcccgccttt ttcctttatt atgaaaaagg cgaacttgtt ggtttattaa ctgtctatgc
    45421 agatgaccaa gatgtagaag tgacgatact ggttcatcca ggtcatcgcc gtcaggggat
    45481 tgcgcgtgca ttgtttacta gttttgagag agaaacagct tctttcccca ttcggtcagt
    45541 cacttttcag acagaacgta tttttttaga gaatcatcct gactttgcca gtaactgggg
    45601 actaatcgag gatgaagaga cagaaacttg gttaggtaag gatagaagac cttatccgtt
    45661 agcaaatgtt tcccatcttg aaattttgtt agcagatagt tcgtatcagg atcaaattag
    45721 tcaattaaaa tttcaggcat tttcagagga acatgaatcg agagaagttg tggatagata
    45781 tgtcgctgaa gctctgaaag atccagaaag ccgactatat attttattaa aagctggtca
    45841 ggttattgga acttgtacgg ttgatttatc gactaatacg aattacctct acggtttagc
    45901 aatattggaa cctgaacgtg gaaaaggcta tggaagctac ttagcaaaat ccctcgtcaa
    45961 ccaactaatt gagcaaaatg acaaggaatt tcagattgca gtggaagata gcaatgtagg
    46021 tgccaaacgt ttgtatgaaa aaattggctt tgtcaaacag actcaggtgg tttatctgaa
    46081 tgagaaagga gcaagggatt ccgaagtgta gagatattcg gactgaaatt tacttgaact
    46141 tttagtgatg aaactaattg ttcttggatt tcagctttcc tgattatgat ttatgattaa
    46201 aatctatgac accatgtctc gtgatttgcg agaatttgtc ccgattgagg acggcaagat
    46261 caagatgtat gtttgtgggc caacggtgta caactatatc cacgtgggaa acgcccgttc
    46321 gacagtagct tttgatacga ttcgtcgcta ttttgagtac cgtgggtata aggttgccta
    46381 tatttccaat tttacagatg tggatgataa gattatcaac cgtgccaggg aagaaggcat
    46441 cacgcctcag gaggttgcgg ataagtacat cgctgccttt cgtgaggatg tgacggcctt
    46501 aggcgtgaaa cctgcgactc gccatccgcg tgtagtggag tttatggcag acatcatccg
    46561 ttttgtggaa gacttgatcg agaaaggctt tgcctatgag agtcaagggg atgtctattt
    46621 ccgtgtagaa aaatcccaca actatgctaa attggctaat aaaaccttgg aagatttgga
    46681 tctaggtgct tcaggtcgta ccgatgaaga aacggctcgt aaggaaaatc ctgtagattt
    46741 tgctctatgg aaatcttcca aaccaggtga gatttcttgg gatagtcctt ggggacctgg
    46801 acgtccgggt tggcatattg agtgttcagt catgtcgaca gagattttag gtgataccat
    46861 tgatatccac ggtggtggag ctgacctaga gtttccacac cacaccaatg aaattgccca
    46921 atctgaagct aaaacaggca aggcttttgc taactactgg atgcacaatg gctttgtcaa
    46981 tatcgacaat gtcaaaatgt ctaagtcctt gggtaacttc attacggtac acgatgccct
    47041 taaaactctt gatgggcaag tacttcgttt cttctttgcg acccagcact accgtaagcc
    47101 tatcaacttc acggaaaagg cagttcgcga tgccgagacc aatctcaagt atctgaagaa
    47161 tacttacgaa caaccattta caggaaacgt ggatgcccaa gagttacaaa actttaaaga
    47221 taagtttgta gcagctatgg atgaagattt taatgctgcc aacggtatca cagttgtctt
    47281 tgaaatggcc aaatggatca actcagggaa ctatgatgca agtgtcaagc aagctcttgc
    47341 agatatgtta gaaatttttg gaattgtctt tgttgaggaa gttttggatg cagagattga
    47401 agacttgatt caaaaacgcc aagaggcgcg tgccaatcga gactttgaga cagcagacca
    47461 aatccgagac caactggctg ctcaaggcat taaactattg gatacaaaag atggagtgag
    47521 gtggacacgt gattgatgtc aatctcatta acgggattgc gctagccttt gagggggatg
    47581 cggtgtattc tatgtatatt cgccgtcacc tcatcctcaa aggtatgacc aaacccaata
    47641 aactccatca agaagcaacc aagtatgtgt cagccaaggc tcaggctcgc ctgattgctc
    47701 tcatgttgga ggagcaggtc ctaacggaaa aagaagaaga aatctataaa cgtggccgca
    47761 ataccaatag ccacacaaag gctaaaaatg cagatgtcgt gacttatcgt atgtccacgg
    47821 gatttgaagc ggttatgggc tatctccata tgactgagaa tctggaacgt cttgagagtt
    47881 tggtttcatg gtgcatccaa aaagtggagg gctagaacat gagggcaaaa gaactacaag
    47941 actggtttcc tgaggctcgg atttcagacc aaccagtaga gaaagagggc tatctcacgc
    48001 tccctttagc ttctcagcag tggattttgc tggaggaagc tgggctcagc gagcgtgaaa
    48061 agcagttggt tgcccttttg acccagcagg agcaggctcg ttcgctaaac ccttggtatt
    48121 cctatctggt tgaaggcaag ggacaggcac cgcaagtttt taaaaagatt cagttggttt
    48181 attgccatct ttcttatttt cagcaggaaa atctggcttc ttggctagat atgatgcgga
    48241 ctctttttcc gaattgtcag acagtgctac aggtcggagc tcaggattat gttttcgtgc
    48301 ttcaacaaga caaatacact tctgtaagag atattttaag tgatacgatt gaagcggttg
    48361 agtatgactt tggacttcgt ctttctatca tgttgggtca ggtttggtct cagacaggac
    48421 atcaagccct atcagactta atcaaagctg agcgggattt gttcaagaca tggtggcgtc
    48481 agggtcacca aggtgttcat actttttctc agctctatct ttggagtatg ggagaaagac
    48541 tcgtggactt gaagccaatt aaagaatgtc tacaccagat gattttggat caagatcaga
    48601 ttcaggaaat cattctctct ctttgggaaa atagtgctgt tctcactaaa acagcccagc
    48661 aactctatct gcaccgcaat tctctccaat acaagattga taaatgggaa gagttgacag
    48721 ggcttcagtt gaaagagttg accgacctga ccttgtgtta tcaattgatt ttaggttctt
    48781 tgtcaactat agttggtttg taaagaagtt aatatttgga gaagaggatt gccatcttct
    48841 ccatttttat gtgcagagtt atagtggctt gatgctggga aagtacactg tgactgctaa
    48901 aacattccta gaagttgctt tgatttacct aatctattta tgcaaatttt atgttatttt
    48961 actataacag ttgttgctaa gccaaataat agtggggaag ttcatttaga cgtaagcatt
    49021 gaagataatc agggaggtag tgggcataat ttcagttctg tttcaagtag ctcacaaaca
    49081 gctaaatatg aagaaactgt ttataataac aattcatcat tatatataac gattgataaa
    49141 acgtctgatg caacagctct tttgaaatta aagttgaata atgttgataa tcaacctgct
    49201 actgaagttc ctagttcagg aattactgta aaattaaatg ctaaagataa tgctggaaac
    49261 tggacaagtg cttcgaataa aaaagaaata acagtaaaaa ttgtttctgc taaaccgaca
    49321 tatccagaca aaatcttagt gaaaaatcct gataatataa aagatacaga aaaaatgcca
    49381 ttattgaaaa attgaaagag gcaaataaaa atcatccagc aggagctcca acctttgcta
    49441 aaggtgaagg agagcatgca aatgatattg tagcaactta ttcagatggt acaacttatt
    49501 atgtaccgtt aaatgatgtg acaaaatatg cgaggtagtg gctgtaccac tcacttattc
    49561 acctccccgt gatttgtagt agtgataggc tttctcacta ttattataaa acaaaataaa
    49621 gatcacaaca ctttttcatt ctgtgttgtg ccttgagtga aacgaaagga atgaattata
    49681 aatatgaaaa gtatagtcac tagcatagat gagcgcttgc gtactcgcct acgagtgatt
    49741 atctggaagc aatggaagaa gaaatcgaga cgattatggg gattgcttaa gttaggggtt
    49801 cctaaatgga tagcagataa ggtatctggc tggggcgacc actatcaatt atagtaaaat
    49861 gaaataagaa taggacgaat cgttcaggac agtcaaatcg atttctaaca at
//
LOCUS       DAVIME010000008        48607 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVIME010000008 DAVIME010000000
VERSION     DAVIME010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.008"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(212..1198)
                     /locus_tag="VV588_000523"
     CDS             complement(212..1198)
                     /locus_tag="VV588_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU7082911.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1208..2008)
                     /locus_tag="VV588_000524"
     CDS             complement(1208..2008)
                     /locus_tag="VV588_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU7082912.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2261..3103)
                     /locus_tag="VV588_000525"
     CDS             complement(2261..3103)
                     /locus_tag="VV588_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7082913.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3105..4397)
                     /locus_tag="VV588_000526"
     CDS             complement(3105..4397)
                     /locus_tag="VV588_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7082914.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4508..5779)
                     /locus_tag="VV588_000527"
     CDS             complement(4508..5779)
                     /locus_tag="VV588_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU7082915.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6328..7845
                     /gene="malQ"
                     /locus_tag="VV588_000528"
     CDS             6328..7845
                     /gene="malQ"
                     /locus_tag="VV588_000528"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU7082916.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7871..10129
                     /gene="glgP"
                     /locus_tag="VV588_000529"
     CDS             7871..10129
                     /gene="glgP"
                     /locus_tag="VV588_000529"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU7082917.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYKVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11174..11746)
                     /locus_tag="VV588_000530"
     CDS             complement(11174..11746)
                     /locus_tag="VV588_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082918.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLTQLWDKNDAIPNNGRINF"
     gene            complement(12371..13219)
                     /locus_tag="VV588_000531"
     CDS             complement(12371..13219)
                     /locus_tag="VV588_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU7082919.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13371..13649
                     /locus_tag="VV588_000532"
     CDS             13371..13649
                     /locus_tag="VV588_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082920.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            13651..15714
                     /locus_tag="VV588_000533"
     CDS             13651..15714
                     /locus_tag="VV588_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU7082921.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(15792..17048)
                     /locus_tag="VV588_000534"
     CDS             complement(15792..17048)
                     /locus_tag="VV588_000534"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU7082922.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            17190..19655
                     /locus_tag="VV588_000535"
     CDS             17190..19655
                     /locus_tag="VV588_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU7082923.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLCFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLATADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            19720..20631
                     /locus_tag="VV588_000536"
     CDS             19720..20631
                     /locus_tag="VV588_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU7082924.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            20861..21559
                     /gene="dapD"
                     /locus_tag="VV588_000537"
     CDS             20861..21559
                     /gene="dapD"
                     /locus_tag="VV588_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU7082925.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            21627..22757
                     /locus_tag="VV588_000538"
     CDS             21627..22757
                     /locus_tag="VV588_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU7082926.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            22769..23308
                     /locus_tag="VV588_000539"
     CDS             22769..23308
                     /locus_tag="VV588_000539"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU7082927.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVAYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            23292..23969
                     /locus_tag="VV588_000540"
     CDS             23292..23969
                     /locus_tag="VV588_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU7082928.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(24036..24935)
                     /gene="galU"
                     /locus_tag="VV588_000541"
     CDS             complement(24036..24935)
                     /gene="galU"
                     /locus_tag="VV588_000541"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU7082929.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(24957..25973)
                     /locus_tag="VV588_000542"
     CDS             complement(24957..25973)
                     /locus_tag="VV588_000542"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU7082930.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            26185..26625
                     /locus_tag="VV588_000543"
     CDS             26185..26625
                     /locus_tag="VV588_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU7082931.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(26748..27164)
                     /locus_tag="VV588_000544"
     CDS             complement(26748..27164)
                     /locus_tag="VV588_000544"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU7082932.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTA"
     gene            complement(27232..27882)
                     /gene="phoU"
                     /locus_tag="VV588_000545"
     CDS             complement(27232..27882)
                     /gene="phoU"
                     /locus_tag="VV588_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU7082933.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(27897..28649)
                     /gene="pstB"
                     /locus_tag="VV588_000546"
     CDS             complement(27897..28649)
                     /gene="pstB"
                     /locus_tag="VV588_000546"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU7082934.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(28651..29466)
                     /gene="pstA"
                     /locus_tag="VV588_000547"
     CDS             complement(28651..29466)
                     /gene="pstA"
                     /locus_tag="VV588_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU7082935.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDIMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(29459..30322)
                     /gene="pstC"
                     /locus_tag="VV588_000548"
     CDS             complement(29459..30322)
                     /gene="pstC"
                     /locus_tag="VV588_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU7082936.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(30440..31315)
                     /locus_tag="VV588_000549"
     CDS             complement(30440..31315)
                     /locus_tag="VV588_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU7082937.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(31482..32813)
                     /locus_tag="VV588_000550"
     CDS             complement(31482..32813)
                     /locus_tag="VV588_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU7082938.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(32814..33521)
                     /locus_tag="VV588_000551"
     CDS             complement(32814..33521)
                     /locus_tag="VV588_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7082939.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(33605..34090)
                     /locus_tag="VV588_000552"
     CDS             complement(33605..34090)
                     /locus_tag="VV588_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU7082940.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            34076..34615
                     /locus_tag="VV588_000553"
                     /pseudo
     CDS             34076..34615
                     /locus_tag="VV588_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34930..36621)
                     /locus_tag="VV588_000554"
     CDS             complement(34930..36621)
                     /locus_tag="VV588_000554"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU7082941.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            36757..37203
                     /gene="argR"
                     /locus_tag="VV588_000555"
     CDS             36757..37203
                     /gene="argR"
                     /locus_tag="VV588_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU7082942.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            37254..39788
                     /gene="mutS"
                     /locus_tag="VV588_000556"
     CDS             37254..39788
                     /gene="mutS"
                     /locus_tag="VV588_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU7082943.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            39935..41629
                     /gene="patA"
                     /locus_tag="VV588_000557"
     CDS             39935..41629
                     /gene="patA"
                     /locus_tag="VV588_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU7082944.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEVIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(41959..42222)
                     /locus_tag="VV588_000558"
                     /pseudo
     CDS             complement(41959..42222)
                     /locus_tag="VV588_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            42416..44182
                     /gene="patB"
                     /locus_tag="VV588_000559"
     CDS             42416..44182
                     /gene="patB"
                     /locus_tag="VV588_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU7082945.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTENKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            44321..45010
                     /locus_tag="VV588_000560"
     CDS             44321..45010
                     /locus_tag="VV588_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU7082946.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQIGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            45014..45193
                     /locus_tag="VV588_000561"
     CDS             45014..45193
                     /locus_tag="VV588_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082947.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            45180..46529
                     /locus_tag="VV588_000562"
     CDS             45180..46529
                     /locus_tag="VV588_000562"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU7082948.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            46653..48113
                     /locus_tag="VV588_000563"
     CDS             46653..48113
                     /locus_tag="VV588_000563"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU7082949.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYSRHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            48127..48561
                     /locus_tag="VV588_000564"
     CDS             48127..48561
                     /locus_tag="VV588_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU7082950.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        14320 a         9240 c        10554 g        14493 t
ORIGIN      
        1 tatccacaac ctcaaaacag tgttttgagc aacctgtggc tagcttccta gtttgcactt
       61 tgattttcat tgagtataaa aagatcttgg gtaacaactc aatttcagta gaaaaggaag
      121 taaatcttcc cacaataaaa cgcatagtat caagtttttt caatacctga tactatgcgt
      181 ttttgctttt aacgactttt tgcccagtct cttatttttc gataattttg tgggcgatca
      241 attgacggta acaaatttgt ttattgtttt tattatcatt aataatctgg agaatagttt
      301 caagggaaac acgaccaagc tctaaactat tgatatcgac ataggctgcc aagttgagct
      361 tgggattaac cgagtcaaag ctgagaacag ggacatccag ctggtgtttg gcaatatagt
      421 tacaaacacc ttcagctagg aggctatcgg ttgtgatgat agcatcaatt tgtggatcgt
      481 gcttgaataa tcgcttgcta aatttatagc ccttttcttc cagaaactcg tcggcaaagt
      541 agatgcgatt gttgtcagtg gtaagtttgt aatgtttaag cgcctgttca tagcctgtta
      601 aacggtcttt ggtcacgaag agctttttac ttcctccgat aaaggcaatg cgtttgcagc
      661 cttttttgat gaaatattca gtcgcatcaa aaccagcttg aacattgtcg ttgtcgacaa
      721 gtgggatgaa aggagataga gatttaccta agataaggaa ggggaactgt tcttctgcga
      781 cgagttttac gagagggtct tcttcttggg catagagaaa gattagccca tctacacgct
      841 tgccgtagac catttgtgaa atagcgttga gacgctcctt ctcatctttc cctgttgcta
      901 tctgaatggc atagtggttt tcagatgcga cttgagagat gccacgtaga accgatggaa
      961 agaaaggatt ctggtagaag gcgtctgagt catcaggaag aactaatccg ataacctgag
     1021 tatagctgct taccaagcta cgagcgttga ggtttgggtg gtagttgagt tccttcatag
     1081 ctttgcgaac gcgttttttt gtttcgtcgc taatggttga tttattttga ataacacggg
     1141 ttacggttga aggcgaaaca ccagcagcct tggccacgtc tttaatcgta acgggcataa
     1201 aaatctccta tttatggtaa tttggatcac ggaaatgtgt tttataaaag atagtgacca
     1261 gatacagaac aaaaagaata ttttgtacag taatcagggt tgtcatattt tggccaaata
     1321 atcccaaaat aagtgtaatc agagtcggca atcctaaaca gttcaagata aagtgatagc
     1381 actctttaaa ggttctaaat gaaaagaggc gtgatttctt agtgatataa aggagaagac
     1441 tagctcctag agagacgata aagaaattca aaccaaagag gaagctcgca ccgagaacta
     1501 ggaagaggct gatatagaca cgattttgtt ggtaccagtc tttagaaatt gcttgggtca
     1561 agctgtcttt gcttttgaaa ctctcagtct gaatggctcg gtaagagatg cgggtcagtt
     1621 ccttgctttc cttgctgatg actagctcat ttgtatcgaa atgcagttgc aagtccttag
     1681 gtaattcctt gatttgactt ggaccaatca caacagaagg ggcttgacta gctgttccag
     1741 tataagttaa tgtgccatcg acaattgtag catgttcaga gagatcctgg acaacctcat
     1801 ttgtcagagg ttcatagaca ttatcgataa aagtttctag cggataggtc tcctgggagc
     1861 tgttttggat agcaatgggt accatagaca agctgataag gaagatactg gtaaagagaa
     1921 gttgaaacca gttgagctcg aaacgtttgg acaggggctt acgaaacccc caaatacttg
     1981 aaaaatagga aaatggatat ggaagcatag gtatctttct aaaaggtgtt ttctatatga
     2041 gtattattat atagagaaat gctctttatt tcaagtctag gagaaaaatt gcttgctaca
     2101 aggatattat ttacagtgac aattgctaat aatcaatgaa aatcaaagtg caaactagcc
     2161 acaggttgct caaagcacaa ctttgaggtt ggagataaag ctgacgtggt ttgaagaaat
     2221 tttcgaagag tataaaatga aaaagggtgg cggggataaa ttatcccttg tcgccaccac
     2281 ttgtaagtcc tgaaacaaag ttcttttgta ggaagaagaa gagaatacag attggaaggg
     2341 cgatgaggat agcacctgct gagaagtagg caatcttcaa gtttttcgca ttgttaacga
     2401 aggtttggag acctacggca acagtaaagt attctttctc acgaagcaag aaactagaga
     2461 ggatgtagtc cccgaaaggt cccatgaagg cccagagagc ttgtacggca accattgggc
     2521 gaacaagtgg tagaacaatt tgccagaagc ggcggaagtg tcctgcaccg tctagttttg
     2581 cagattcgtc taaagacatt ggcactgtat cgaagtagcc tttcatgagc caagcattca
     2641 tcgggatacc accaccaacg tagaggaaga tgaggaacca gttgtggtta agggcgttca
     2701 acataagcgc cataacgaag aaggctgtca aagcggccat agttggcacc atttggatga
     2761 tcaagaagaa gaccaaactt tgtttacgag ccaagaagtt gtaacggctg taggcataac
     2821 cagcaagtac gatgatactt gtttgaacag ccatggtaat taaggcgata atcaaagtgt
     2881 tgaggtacca agtaccgtac aaggtttcag tgaagaggcc tttaaagtta tcaaaattga
     2941 ggtcgatatt agtatctagt ttaaaggctg agacgttacc tgctttaaag gctgacataa
     3001 tggtaatcaa cagtggatag ataattacaa ttgatagacc aatcaggtaa aggtaagtaa
     3061 ggctttgagt cagtctacgt ttgagtttaa ttgagttatt catcttagac gtcctccata
     3121 tcaaatgcgt gtagtttctt gaatgcgatc atagagattg agatgacaat gatagagata
     3181 atcaaggtaa cagctgccgc cattgagtat tgaggagatg tacctgttgt caaacggtag
     3241 atccatgaga tcaagatatc ggttgaacca gctccacctc cgacactacc aggtcctcca
     3301 ccattgaaga ggtacatgat agagaagttg ttaaagttga aggtgtattg gctaatcaaa
     3361 gtaggtgccg caacagccaa aatcattggg aaagtgatgt tgcggaattt ttgccaagcg
     3421 ttggcaccgt caatataagc tgcttcgtaa aggtcgttag gaatagattg caagataccc
     3481 aaagtcaaaa cgtagatgta tgggaatccg agccaacctt gcatcataat caaggcaatc
     3541 ttagtccaag ttgggtctgt tttccaagga ataagagctc catcaaggaa aggaaggaat
     3601 ttagccaaga ttggcaatac ttgagtgttg atagcaccga cactatcgtt aaacatgttt
     3661 gagaatgtca agatagtgat gaaggctggg acagcccaag gaagaaggaa aataacacca
     3721 aagatacgtt ttcctttgat aaatggttgg ttggcaatga tagctgtgaa gataccaatt
     3781 acgatttgta aagtagaagc tgccaaagcc caaatgatag tccaagaaag aacagaacca
     3841 aaggcagaac ggaaggtact caagctccaa atgtttgtaa agttggtcaa accaacccag
     3901 tccaacaact tgtttggtgg caagtgttgg aagtcgtagt tggtaaaggc gatcatcaag
     3961 gttacgataa ctgggaagat aatcgcgaag gtcatggcaa cataagatgg aatgatcaag
     4021 aggtaaggga agccattttc ataaatccct ttgatcatgt ctttgagtgt gcgtggaact
     4081 ggaattccat tgttaatgcg ttttgcaatc gtatgtgcat ctttgatatt tgagaaataa
     4141 aagagtacat aaacgattac aaagattaga tggaaggcac cacgaatcag cataaagagg
     4201 gaattatcac gacctggttt gtcaccaaga gtgatgaggt tgctcaattc aggggttgca
     4261 agtgctagga agtaaaggac aaatacgatg gttacaccaa ggaagataaa acctttggct
     4321 ttttgtttat tgtaaatctg tcctaaccca ggaatgatag acagcagggc tgctttacta
     4381 ggttgttgct tttccatatt aactcctttc ataggatact acttttttat aagaaagcta
     4441 aattatttgt gtctctattg ataaattcaa agggggattt gatttccacc ccccttgaac
     4501 aaatttttta ttcaccaaat ttttgtttga ttgtttcttt gatcaatgtt acagcatcgt
     4561 tagcagctgt tttagcatct ttttgaccac ttacagcatc aaagagcata tttttcgctg
     4621 gatcccaaac tgcagacatt tgagagatgt ttggcagtgg ttgagtgttc ttgaactgtt
     4681 tgataacagc tgttgtcaac tcatcgtttt taccttcagc gtatgaacga gcctcagtat
     4741 tagctgggat ttcgttagtc ttatcatata atactttttg ttgttcagtt gcaacaagga
     4801 agtctacaaa tttttgagaa gcttcaaggt tcttaacggc ttgaggaatg acccaagctt
     4861 taccaccacc gaatgcagca tattcttttc catttggaag agttgggata gttgcaactc
     4921 cgtagtttac tttagcatct ttaaaggctt gagctttcca aggtccgtcg atgatagcag
     4981 ctgttttacc ttcttggaat tgagtttgga ttaagtttcc agcaccttct gtatcttgca
     5041 tacctttagg ccatttttcg taccaagatt tagcgtagtt gatacctgcg atagaaccgt
     5101 cgtttgcaag accgatgtct ttagcgtctt taccgttttg gccaaagacg taagcaccgt
     5161 taccggcaag aagtccatat gtatagtaga agtttgtcca gtcagctagg aaggcagtag
     5221 ttttaccatc ttcaccagcg aatgcgtatt tgctatcttt agcaaggttt tccaagtcag
     5281 caaatgtttt tggagcatct ttcaccaagt ctttgttgta gtacataaca agtgactcga
     5341 taacggcagg agcaccgtaa actttaccat tagcagctgt tacaagagat ttagttgtgt
     5401 cgtctgtttt agcaccatcg ctcaatttca cttctgaaag ttgtccgtca gaaccaaggc
     5461 tacctacacg gtcgtatgga gccatcataa catcagggac attaccagat tggttgtcaa
     5521 gagaaagttt atcaagacct cctagagcat caccagtttt aagagtgact tttactccag
     5581 cttctttttc ataagcttta gcaacctctt caatatagct cttatatccc tcgtctacat
     5641 atacagtgag ttctttgact tcagatgaac cagaatcagc aggcttatca gcagttttgc
     5701 ttccgcaagc taccaaaagc aagctagcaa gtgtagcagt tccaagcacc gcagtgctct
     5761 tcataaattt agatgacata gtgtattcct cctaaagaat agcaagtttt attgataagg
     5821 aaacgcaaac gttttccttt atgagcttag tatagcacaa atagaaaacg gttgcaagta
     5881 ttttttgtaa aaattttaaa aaatttttaa gcttgatttg atagtataat tttgcatttt
     5941 aatagaagaa aagtatgaaa tagataagaa tacagtattt ttaataaaaa tatatggaat
     6001 ctgtctaaag agggaaatca ggaggggtac ctccctgttt ctaatctata tctattttct
     6061 atagacgttt gtgctttgtt gcatataaat tcaagctccc taaggaggtt ttgtactttg
     6121 tatactgtct cgtgagagtc aaactttagg attagatagt tttaagttat ctttgctaaa
     6181 atgagttagt ctccttaaaa ataatcaaaa aagtttttta aaaacgcttg caattatgct
     6241 tgaaaaggag tatacttata agtaacgcaa acgtttgcgt ctgaaaaata cgcaacgttc
     6301 cattatttta acacacgagg tgctattatg aaaaaacgtc aaagtggtgt gttgatgcac
     6361 atctcttctc ttccaggagc ttacggaatc ggatcatttg gtcaaagtgc ttacgacttc
     6421 gttgatttct tggtccgtac aaaacaacgt tactggcaaa tccttccatt aggagcaact
     6481 agttacgggg attctcctta ccaatctttc tcagccttcg caggaaacac tcattttatc
     6541 gatttagata tcttggtgga gcaaggtttg ttggaagcaa gtgaccttga aggagttgac
     6601 tttggtagcg atgcgtctga agttgactat gctaaaatct actatgcacg tcgtcctctt
     6661 ttagaaaaag cggtgaaacg tttctttgaa gtcggagatg ttaaagattt tgagaaattt
     6721 gctcaagaca accaatcatg gcttgagctc tttgctgagt atatggctat caaagagtat
     6781 tttgacaatc ttgcttggac tgaatggcca gatgcagatg ctcgtgctcg taaagcttca
     6841 gcacttgaaa gctatcgtga gcaattggca gacaagttgg tttaccaccg tgtgactcaa
     6901 tacttcttct tccaacaatg gttgaaattg aaagcttacg ctaacgacaa ccacatcgaa
     6961 atcgttgggg acatgccaat ctacgtagcg gaagattcaa gtgatatgtg ggcaaatcca
     7021 catctcttca aaacagatgt caatggtaag gctacttgta tcgcaggatg cccaccagat
     7081 gagttttctg taactggtca gctttggggt aatccaatct atgactggga agcaatggac
     7141 aaagacggct acaaatggtg gattgaacgc ttgcgtgaaa gcttcaaaat ctacgatatc
     7201 gttcgtatcg accacttccg tggcttcgaa tcttactggg aaatccctgc tggttccgat
     7261 acagcagcac ctggtgagtg ggtgaaaggt ccaggctaca agctttttgc agccgttaag
     7321 gaagaacttg gtgagctaaa catcatcgca gaagaccttg gcttcatgac agatgaagtg
     7381 atcgaattgc gtgaacgtac tggcttccca ggaatgaaga ttcttcaatt tgccttcaac
     7441 ccagaagacg aaagcattga tagcccacac ttggcacctg ctaactcagt tatgtacaca
     7501 ggaacacacg ataacaatac ggttcttggt tggtaccgta atgagattga tgatgcgact
     7561 cgtgagtaca tggctcgtta cacgaaccgt aaagaatacg aaacagtggt acacgctatg
     7621 cttcgtacag tattttcatc agttagcttt atggcaattg caactatgca agatttacta
     7681 gaattggatg aggcagctcg tatgaacttc ccatctaccc ttggtggaaa ctggtcttgg
     7741 cgtatgactg aagatcaatt gacaccagct gtcgaggaag gtttgcttga cttgacaaca
     7801 atttatcgcc gaattaatga aaatttggta gatttaaaga aataagacaa taatcaggag
     7861 acaactaaac atgttatcac tacaagaatt tgtacaaaat cgttacaata aaaccattgc
     7921 agaatgtagc aatgaagagc tttaccttgc tcttcttaac tacagcaagc ttgcaagcag
     7981 ccaaaaacca gtcaacactg gtaagaaaaa agtttactac atctcagctg agttcttgat
     8041 tggtaaactc ttgtcaaaca acttgattaa ccttggtctt tacgacgatg ttaaaaaaga
     8101 acttgcagct gcaggtaaag acttgatcga agttgaagaa gttgaattgg aaccatctct
     8161 tggtaatggt ggtttgggac gtttggctgc ctgctttatc gactcaattg ctactcttgg
     8221 tttgaatggt gacggtgttg gtcttaacta ccactttggt cttttccaac aagttcttaa
     8281 aaacaaccaa caagaaacaa ttccaaatgc atggttgaca gagcaaaact ggttggttcg
     8341 ctcaagccgt agctacaaag taccatttgc agactttact ttgacatcaa ctctttacga
     8401 tattgatgtt actggttatg aaacagcgac taaaaaccgc ttgcgtttgt ttgacttgga
     8461 ttcagttgat tcttctatta ttaaagatgg tatcaacttt gacaagacag atatcgctcg
     8521 caacttgact ctcttccttt acccagatga tagtgaccgt caaggtgaat tgctccgtat
     8581 cttccaacaa tacttcatgg tttcaaacgg tgcgcaattg atcatcgacg aagcaatcga
     8641 aaaaggaagc aacttgcatg accttgctga ctacgcagtt gtccaaatca acgatactca
     8701 cccatcaatg gtgattcctg aattgattcg tcttttgact gcacgtggta tcgatcttga
     8761 cgaagcaatt tcaattgttc gtagcatgac tgcctacact aaccacacaa tccttgctga
     8821 agcgcttgaa aaatggcctc ttgaattctt gcaagaagtg gttcctcact tggtaccaat
     8881 catcgaagaa ttggaccgtc gtgtgaaggc agagtacaaa gatccagctg ttcaaatcat
     8941 cgatgagagc ggacgtgttc acatggctca catggatatc cactacggat acagtgttaa
     9001 cggggttgca gcactccata ctgaaatctt gaaaaattct gagttgaaag ccttctacga
     9061 cctttaccca gaaaagttca acaacaaaac aaacggtatc actttccgtc gttggcttat
     9121 gcatgctaac ccaagattgt ctcactactt ggatgagatt cttggagatg gttggcacca
     9181 tgaagcagat gagcttgaaa aacttttgtc ttatgaagac aaagcagctg tcaaagaaaa
     9241 attggaaagc atcaaggctc acaacaaacg taaattggct cgtcacttga aagaacacca
     9301 aggtgtggaa atcaattcaa attctatctt tgatatccaa atcaaacgtc ttcacgagta
     9361 caaacgccaa caaatgaacg ctttgtacgt aatccacaaa taccttgaca tcaaagctgg
     9421 taacatccct gctcgcccaa ttacaatctt ctttggtggt aaagcagctc cagcctacac
     9481 aatcgctcaa gatatcattc acttgatcct ttgcatgtca gaagttattg ctaacgatcc
     9541 agcagtagct ccacacttgc aagtagttat ggttgaaaac tacaacgtta ctgcagcaag
     9601 cttccttatc ccagcatgtg atatctcaga acaaatctca cttgcttcta aagaagcttc
     9661 aggtactggt aacatgaaat tcatgttgaa cggagctttg acacttggta ctatggacgg
     9721 tgctaacgtg gaaatcgctg agttggttgg agaagaaaac atctacatct tcggtgaaga
     9781 ttcagaaact gttatcgacc tttacgcaaa agcagcttac aaatcaagcg aattctacgc
     9841 tcgtgaagct atcaaaccat tggttgactt catcgttagt gatgcagttc ttgcagctgg
     9901 aaacaaagag cgcttggaac gtctttacaa tgaattgatc aacaaagact ggttcatgac
     9961 tcttcttgac ttggaagact acatcaaagt caaagagcaa atgcttgctg actacgaaga
    10021 ccgtgacgca tggttggata aagtcatcgt taacatttct aaagcaggat tcttctcatc
    10081 tgaccgtaca atcgctcagt ataatgaaga catctggcac ttgaactaat actcttcgaa
    10141 aatctcttca aaccacgtca gctttatctg caacctcaaa gcggtgcttt gagcaacctg
    10201 cggctagctt cctagtttgc tctttgattt tcattgagta taagatgcaa atttatacta
    10261 atacattttg taaaaaagcg agtttcgatt gaaattcgct tttttaaatg ctgtggattt
    10321 gggtcaatct tgtctaaaaa tagggaaatc ctagatacag tgaaggcttt aaatgctggt
    10381 ttttactgtc ttcagcctta tattttttcg tagttggtta cctcatatct cttgtattcg
    10441 cttacataaa gtattataat ataattgtag gaaagaaggt gtttttatga tatacacact
    10501 taaattggtg ttgtttatta cctttcttgt aataagcttg ttacctgata agatttttgg
    10561 aaaaaataaa aaaatttgga aaatagtttt tgcaatattg acggcagtgg cagcatttat
    10621 atttatgtac taagttattt taagaatgta gggaaataaa ccctacattc tttttagttt
    10681 tttctgtttt ctaaattcta tttatccaag cgcttcaaca tttcttgctt cttcgcttca
    10741 agttctgcac gcttttcttc gatttcggca tgttttttct cgagttcaga acaacttgca
    10801 ccattgctaa attcttttcg ccatcaggag atagggtgag tcgacatgtc tattactcac
    10861 ccaaagcagt cctacaaagc aggaattttc tgttactttt ttggaaatag taacgtttat
    10921 acagctttga cacttcgtat caaagcgcca aacacactcc gagggattta cagaaagcag
    10981 aaaaggaatg atctggtata agatcattcc ttttctctct ttttctttaa gtaattatat
    11041 acaatgtacg acgaagtcgt cattgcaatg ctgatccacc acctaaaggg aactttaaac
    11101 aacattgata agataaagaa tataaacaac gaaaatacgt tatacccaat taattttatt
    11161 gtatatctca tgattaaaag ttaatccttc cgttgttagg aatggcatca tttttatccc
    11221 ataattgtgt taaataagtc cccggtgata ataaattcat agcggattct aaagcaacat
    11281 catttacaaa ccaactacct agatatctag aaattgctga acgaatagca ctttttgctg
    11341 catgttttcc ttttacttta attagatttg caaggcctgc agtagttcct cctaatgcta
    11401 aagctattgc agtatctaat agagcaccca tttgattaac tgtaatacct tgccaagctg
    11461 ctctaaatgg agagtatgta ggtgggattg tataatcgcc ttgtaattgt cggttaatta
    11521 cttctttgat ccattgttgt gagacgtctg gatgaaaaga ttggatttcg tttgcaagtg
    11581 tattgatttg ttcttctgtt agagaagtga caggttgaag ttccatattt gtttcaattt
    11641 gtgatacttg ttcagaagcg tatacagctg aaacacttgg aatcgctgat acaattaaca
    11701 caattgacgt caaaaaaacc gaaataaatt tcattaattt gttcatgagc ttttctcctt
    11761 tttatttgta tttgcttaca ttttattata tactgttatt atagtcaaga aaaatatgct
    11821 attatgttaa aaaaatattt ttcaaaatat aaatggacgg atttattttg gattcttttt
    11881 gtaattgggg catgcctctt gacgggtaat agtagtcttt tcccccttac ccatcaagaa
    11941 ttctcttttc gtggtagcgt ttggggtctg gtactggcct tatatcactt attgttcatt
    12001 gataagtttg taatttcgaa tcgaaaataa aaattagaac tatgattgac tggctacttt
    12061 taatattgat tttggaggaa gattttgtct ctattattta ttattttaaa tttatctatt
    12121 ttgtacaaga tttattcttt gagacgggag aagtcgaaat acttgattta tacggcctat
    12181 atcatatttg gggtaaatgt agtatatggt attcaatggt tattaaaaga actgatttca
    12241 actatttcca cttaatatgt atgaaaacta taacaaaacg cataagatta aggtttttaa
    12301 gcacctgttc ttatacgttt ttgtaatatt gaagattttc ggtaagtttt ctacttttgc
    12361 gaagtctagt ttagaatgct ttcccaacca aaatctctgc ttcgatggta atctctgtca
    12421 gttggctcca gtcaatcttg ctctggtcaa cgtgaaagag gagaggagtc atactgagta
    12481 gggcttggag ttgttctgct gtgatagtct tagtcagaga ggcagtttga ctagatagga
    12541 tggtaaagtg ttcctggaaa tgctccttga tatcttggtt agaatactcc ttgtttgtca
    12601 gctggtcctg tactctttga cggatttctt tgaggtgatt ttcagttggg ataaccttta
    12661 tcaagatacc gtctttggat aaaacgcgac gaaattctcc atagttggca ggtgagaaga
    12721 tatcaagcag aatatccatg ttagcgtctt ttataggaag tcgtgccaag tcgccaacga
    12781 accaattgac tgcccagttg ggttcacttt tagcagcgat ttggactgaa tctttggaga
    12841 tgtcaaaggc atagaaagtt ttttcagagt gactttcttg tagtttgcga gaatagaatc
    12901 cttcaccaca accgatatcc aaaattgttg tggtagtttt tgagcttgca agcaagtcag
    12961 atacagcatc taagatagct tggtaaaagc cggcttctag gatttgttga cggttttgaa
    13021 aattttcctt gtcatagtta gcagattgct tgatttgagg tgctagattg acatagccaa
    13081 atttcgccaa gtcaaaagaa tgacggttgc agcacttgaa attagtctct aacagagtca
    13141 gattttcttg acagatagga caggcaaagg cagtcgcaga agcaaaacgc tgaagtttgg
    13201 gcttgagatt tgtattcata gtttaagtgt atcaaaagag gcaaatgaaa gcaactttag
    13261 gaataagtag atgggagatt cagtagaaat aaaactaatt ctccaattta tagaatgaaa
    13321 ttgcttttat atctaaattg ctatataata atgataagga ggaaataagt atgttaaaag
    13381 aagtattaac cgttgcaaaa gttgcgaaaa aatcttcatt atttttgggt ggtgtcgcat
    13441 ttggtaccct tggtttgaaa atcttagcaa gtaaggaagc taaaaaaggt tattctaaag
    13501 ctttggctaa ggcttacaag ttgaaagacg agctagatgc atctgtttct gttgtgaagc
    13561 aacatggaga cgatgtcttg caagatgcca aatatttgta cgagcaagag aaaaaagaag
    13621 agcaattaga tagccttata ggtgaataat atgtctttta aagtgctaca tagaggatac
    13681 caacatatcc gactatcatc ttctttttca cttaccttgg atattcaaga ctatcttcgt
    13741 tccttggcga gagatgaaaa ggggattgag tctatccagt tttacatgga tcaacagcac
    13801 tttactctac gcataaaaga aggcttttct gtattagata atgcagaagc ctttttaaaa
    13861 agaattgata aagggaaagt ttctgagttg atgactcttc ccattcgtag agaagagagt
    13921 gcttattcta ttgtttcagg tgcagcggtt aagcgtgtac tttttcgtag ttttgtgccg
    13981 tatcctattc gctatatatg gacttgttat caggctttgg gttatattag agaagcctat
    14041 caaacactag cgcgtaagga actaacgatg gaagtcttgg actgttcggc tattttattg
    14101 tccttgttta tgaaccaatc caagacagct agcaatatca tgtttatgct tgatttgggg
    14161 aatcatttag atcagtggtc cttgaaaaaa actgcaacag atttagaaca gagtcttctt
    14221 gcaaaagaga gcgatgtatt cctagtacag ggcgatacgg ttgttagtat aaagagttcc
    14281 gatgttcaaa taggagatgt cttgatctta tctcaaggaa atgaaattct gtttgatggg
    14341 caagtagttt caggtttagg tatggtcaac gaaagttcct tgacaggaga gagttttcca
    14401 gttgaaaaaa gagagtctga tttggtttgt gcaaatacag tattagaaac tggagagtta
    14461 cgcattcgtg taacagataa tcagatgaac agccgtattt tacagctgat tgagttgatg
    14521 aagaaatctg aagaaaacaa gaaaacgaaa caacgctatt tcatcaagat ggcggataaa
    14581 gtcgtcaaat ataatttctt gggggctggg ctgacttacc tattgacagg ttctttttct
    14641 aaggctattt ctttcctatt ggtcgatttc tcctgcgctt tgaaaatctc tactcctgta
    14701 gcttatttga cagttatcaa ggaggggttg aaccgtgaaa tggtgattaa ggatggagat
    14761 gttctggaga aatatctgga agttgatact ttcttgtttg ataagacagg aacaatcaca
    14821 actagttatc ctatagttga aaaggtgtta ccttttggag actatagtga ggaagatatt
    14881 ctcagaatca gtgcctgtct tgaggaacac atttatcatc ctattgctaa tgccatcgtc
    14941 aagcaagctg agatagaggg aattgaacat gaggaaatgc atgggaaact ccaatatatc
    15001 gcaagcaagg ggatcaaatc tcatatagat ggccaaccag ttcttattgg gaattatgtc
    15061 ttgatgcagg atgagcagat tcatatcagt tcagaacaaa atgctttaat tgaagagtac
    15121 aagagtcact acaatctctt attcttggct tatcaaaatg aattgattgg aatgttctgc
    15181 attcatactc ctttgagaaa agaagcaaaa acagccttgg ataaacttaa ggcacagggg
    15241 aaaaaattga ttctggcaac aggagacacc ttgattagga cagaggaatt agtcaaagat
    15301 ttgccctttg atcaggtcta tacagacttg aaacctgatg ggaaatttga gttagtagag
    15361 aaactgcaga aagcaggtca cactattttg atggttggag atggcttgaa tgactcagcg
    15421 gctttaactc tatcagatat cggtgtggtg atgaatgaga gtgcagatat ttctaagcag
    15481 atgagtgata tcttattgtt agataatcgt ttggatttct tccaagagtt ggattcgtta
    15541 tcatcatctt tgcaaacact catcaagaaa aatattcagg ataccgttgt cgtaaatagt
    15601 agtttgattg gctttggctt atttaattgg ttcagtcctt caaatctctc tatcttacat
    15661 aatctaacaa ccttgcgcat tgtcctgcgt agcctgtcta ttaaaaatag atagatgaga
    15721 gttattaaca gcaaaaagga gttacctttc tcgaggttaa ctcctttgtt tatagataaa
    15781 tgttgaatag tttagtaagt caatacaaag tattttttct tcccacgacg gataacagtc
    15841 agttcatttt ctaacttatc agcgtcactc aagacatagt caaggtcttg gatgcggtcg
    15901 ccgtttacgt agatggctcc gttttggacg tcttcacggg cttggcgttt tgagttaact
    15961 ataccagatg agacgagcag ttccacgata ttgttgtttt cgtctgcctg tacttggtag
    16021 tttggcacac cacgaagtcc ttgtttgagc tctttgacag aaaggttttt gatgtttcct
    16081 gcaaagagtt gctcagtgat gttaagtgct tctttgtagg cttcttctcc gtgaacaagt
    16141 gtaacaactt cacgagccaa gactttttga gccaagcgtt cgtgtggcgc tgcttcaaat
    16201 tgtttacgaa tatcttcaat ctcatcaagt gacaagaaag taaagatttt caagaagcga
    16261 acagcgtcag cgtccatcac gttcatccag aattggtaca tttcgtatgg agaagtcttt
    16321 tcgggattga gccagacggc atttccttct gatttaccaa atttcttacc agttgcatct
    16381 gtgattagtg gaacagtgat aacgtgacca gtcttgtccg ccttacgacg aagcaattcg
    16441 gtaccagctg tcatatttcc ccactggtca gaaccaccga tttgaagagt gacattatgg
    16501 tcttggttaa ggacgaagaa gtcgtaccct tgcatgattt ggtaagcgaa ctcagtgtaa
    16561 gaaattcctg tttcgatccg ttttttaaca gattccttac tcatcatgta gttgaccgtg
    16621 aagtattttc caatatcacg gaggaagtca atgaagctga tgctgccaaa ccagtcgtag
    16681 ttgttgacca tgacagcctt gttttcgcca ttttcaaagt caagaaaacg agaaagttgt
    16741 ccttggatag acttgaccca gccatctact gtgtcttttg tttggagact acgttcagca
    16801 tctttgaagg acggatctcc gatgagacct gtagcaccgc caacgagcgc ataaggtttg
    16861 tgacctgcta gttgcaagcg acgacttgtc aagattgcga caaggtggcc taggtgaagg
    16921 ctgtcagcag ttggatcgta gccagtatag taagaaactt gaccttcttc tagggcttta
    16981 cgcaaagctt cttcatcagt cgtttgaaat atcaaaccac gctcttttag ctcatcaaaa
    17041 atgtgcatgt gtcttttctc ctttttaaaa ttattgtttc tacctattgt atcacaaact
    17101 tgggcaatag cctagcagaa tagggaagaa agtggctatt ttattgaaaa tttccctttt
    17161 gtggtataat agataaagtg aggaaatcca tgcaaaatca attaaatgaa ttaaaacgaa
    17221 aaatgctgga atttttccag caaaaacaaa aaaataaaaa atcagctaga cctggcaaga
    17281 aaggttcaag taccaaaaaa tctaaaacct tagataagtc agccattttc ccagctattt
    17341 tactgagtat aaaagcctta tttaacttac tctttgtact ctgttttcta ggaggaatgt
    17401 tgggagttgg gattgctttg gggtacggag tggccttatt tgacaaggtt cgggtgcctc
    17461 agacagaaga attggtgaat caggtcaagg acatctcttc tatttcagag attacctatt
    17521 cggacgggac ggtgattgct tccatagaga gtgatttgtt gcgcacttct atctcatctg
    17581 agcaaatttc ggaaaatctg aagaaggcta tcattgcgac agaagatgaa cactttaaag
    17641 aacataaggg tgtagtaccc aaggcggtga ttcgtgcgac cttggggaaa tttgtaggtt
    17701 tgggttcctc tagtgggggt tcaaccttga cccagcaact aattaaacag caggtggttg
    17761 gggatgcgcc gaccttggct cgtaaggcgg cagagattgt ggatgctctt gccttggaac
    17821 gcgccatgaa taaagatgag attttaacga cctatctcaa tgtggctccc tttggccgaa
    17881 ataataaggg acagaatatt gcaggggctc ggcaagcagc tgagggaatt ttcggtgtag
    17941 atgccagtca gttgactgtt cctcaagcag catttttagc aggacttcca cagagtccca
    18001 ttacttactc tccttatgaa aatactgggg agttgaagag tgatgaagac ctagaaattg
    18061 gcttaagacg ggctaaggca gttctttaca gtatgtatcg tacaggtgca ttaagcaaag
    18121 acgagtattc tcagtacaag gattatgacc ttaaacagga ctttttacca tcgggcacgg
    18181 ttacaggaat ttcacgagac tatttatact ttacaacttt ggcagaagct caagaacgta
    18241 tgtatgacta tctagctcag agagacaatg tctccgctaa ggagttgaaa aatgaggcaa
    18301 ctcagaagtt ttatcgagat ttggcagcca aggaaattga aaatggtggt tataagatta
    18361 ctactaccat agatcagaaa attcattctg ccatgcaaag tgcggttgct gattatggct
    18421 atcttttaga cgatggaaca ggtcgtgtag aagtagggaa tgtcttgatg gacaaccaaa
    18481 caggtgctat tctaggcttt gtaggtggtc gtaattatca agaaaatcaa aataatcatg
    18541 cctttgatac caaacgttcg ccagcttcta ctaccaagcc cttgctggcc tacggtattg
    18601 ctattgacca gggcttgatg ggaagtgaaa cgattctatc taactatcca acaaactttg
    18661 ctaatggcaa tccgattatg tatgctaata gcaagggaac aggaatgatg accttgggag
    18721 aagctctgaa ctattcatgg aatatccctg cttactggac ctatcgtatg ctccgtgaaa
    18781 agggtgttga tgtcaagggt tatatggaaa agatgggtta cgagattcct gagtacggta
    18841 ttgagagctt gccaatgggt ggtggtattg aagtcacagt tgcccagcat accaatggct
    18901 atcagacctt agctaataat ggagtttatc atcagaagca tgtgatttca aagattgaag
    18961 cagcagatgg tagagtggtg tatgagtatc aggataaacc ggttcaagtc tattcaaaag
    19021 ctactgcgac gattatgcag ggattgctac gagaagttct atcttctcgt gtgacaacaa
    19081 ccttcaagtc taacctgact tctttaaatc ctactctggc tactgcagat tggattggga
    19141 agactggtac aaccaaccaa gacgaaaata tgtggctcat gctttcgaca cctagattaa
    19201 ccctaggtgg ctggattggg catgatgata atcattcatt gtcacgtaga gcaggttatt
    19261 ctaataactc taattacatg gctcatctgg taaatgcgat tcagcaagct tccccaagca
    19321 tttgggggaa cgagcgcttt gctttagatc ctagtgtagt gaaatcggaa gtcttgaaat
    19381 caacaggtca aaaaccaggg aaggtttctg ttgaaggaaa agaagtagag gtcacaggtt
    19441 cgactgttac cagctattgg gctaataagt caggagcgcc agcgacaagt tatcgctttg
    19501 ctattggcgg aagtgatgcg gattatcaga atgcttggtc tagtattgtg gggagtctac
    19561 caactccatc cagctccagc agttcaagta gtagttctag cgatagcagt aactcaagta
    19621 ctacacgacc ttcttcttca agggcgagac gataattctc taaatgaagt ggccaatcaa
    19681 tggattgcca cttttttctt ttcgtgttac aataagggta tgaatcagta tcagaaaaag
    19741 attgttaacg gaaaaattta ttcgctccta tccggcttaa tatggggaat ctgtggaatt
    19801 ttaggagagt acttctttac tcattatcag gtgtcttcgg gctggattac ctctatgcgt
    19861 ttgacactgg cagggagtct tgtactcatt tggtctgcaa tacaattaaa atcgcaagtg
    19921 ctagatattt ggcgagacaa gaaaaattac ctgccctttt tagcctatgc tattttgggg
    19981 attttttcag ttcagtattt tttctatctc tgtgtagaat actcaaatgc tacgacagca
    20041 actattttac agtttattag ccctgtcttt atcctctttt acaatcgctt ggtttatcaa
    20101 aaacgagcgt caaaaagcgc tgttttctat gttttggttg ccatgctggg tgtttgcttg
    20161 atggcgacaa agggagacct ctctcagtta tccatgacgc cgctagctct tataacaggt
    20221 ttgctgagtg ccatgggtgt tatgtttaat gttatcttgc cccaaccttt tgctaagcgt
    20281 tatggttttg ttcctacggt tgggtggggg atgattttgg caggtttgtt tagcaatgtc
    20341 ctctcgccgg tttatcagct ttcctttact cttgatattt ggagtatctt gatttgcctc
    20401 attatcgctt tctttggaac ggcttttgct tttttcattt ccatgaaggc tgtgtccttg
    20461 gtttctcctt tggtggttgc cgttatcagt gccagtgaac ctctctcttc tgctctcttg
    20521 agtgttttgt tcttaggatt agtagtggat tggtccctcc ttctagctat agccttgatt
    20581 attttaccca tgatattttt gtctatagaa gaagcgaaag aaagtagata aaaagtcttt
    20641 tcttaattct aaaagtgtgc tatactggaa tagtcaataa aacacgggga gatagttgtg
    20701 aagagtgttt ttaggttgta tcggtagggg cttgctttta ccgacagcac gttttatctc
    20761 acatccctaa aaaatcatac ctaaaaacag acaaaaaggt ttcaaatttg aggccttttt
    20821 tggtagaata ggtatcatta taacgaacca ggaggcacct atgactgcta caaaaatgaa
    20881 cgctcaagaa attatccaat ttatcgccaa tgctgaaaag aaaaccagtg tcaaagtaac
    20941 ctttgagggg caactcgcaa ctgctgtgcc tagctctgtt gtcaaactag gaaatgtcct
    21001 attcggagac tggaaggacg tggctccgct tcttgaaggt ttggtagaaa atcaagatta
    21061 tgttgtcgag caagatgctc gtaattctgc agttcctttg ctagataagc gtgctatcaa
    21121 cgctcgtatc gagccaggtg ctattatccg tgaccaggtg gaaattggtg acaatgctgt
    21181 tatcatgatg ggagctgtta tcaatatcgg tgctgaaatc ggtgctggaa ccatgattga
    21241 catgggtgcc atccttggtg gccgtgccat tgttggaaaa aatagccacg ttggtgcagg
    21301 tgcagttttg gcaggtgtga ttgagccagc tagtgctgaa ccagtccgtg tcggagacaa
    21361 tgttctcatc ggggctaatg cagtggttat cgaaggagtc caaatcggta gtggttcagt
    21421 tgtcgcagca ggagctattg ttacccaaga tgtcccagaa aacgtggtag tagcaggtgt
    21481 tccagctcgt attatcaaag aaattgatgc ccaaactcaa caaaaaacag cgctagagga
    21541 tgcgcttcgt accttgtaat tgtaaaagta aaaaagaggc ggaacccttt ttccagcctc
    21601 tttctgctat atcggaggac agatagatgt tagatttgat tcagactaga cgagatttac
    21661 accagattcc agagattggc ttggaggagt tcaagactca ggcttatttg ctggatgtga
    21721 ttgagaaatt gactacgggc aaggattttg ttcaaattcg tacttggcgg acagggattt
    21781 tggtctacct gcagggaagt cagccggagc gaaccattgg ttggcggaca gatattgatg
    21841 gcctgcctat cgtcgaacaa acaggtctac cttttgcttc tcaacaccaa ggtcgcatgc
    21901 atgcctgtgg tcatgatttt catatgacca ttgccttagg ctgtcttgag cgcgcccttg
    21961 aggagcaacc caagaataat ctgctctttc tatttcagcc tgctgaagaa aatgaagctg
    22021 gtggtatgct catgtatgag gacgatgctt ttggagattg gttgccagat caattctatg
    22081 gtctccatgt tcgtccagat ttgaaagtcg gccagattgc gactaatact catacactct
    22141 ttgcaggaac ttgcgaggtg aagatccgtt tcaaaggcaa aggtggccac gcagcttttc
    22201 ctcatgaagc caatgacgcc ttggtggcgg ctagttactt tgtgacccaa gtgcagtcag
    22261 ttgttagccg caatgtcaac ccaatcgagg gagcagtggt gaccttcggc gtttttcaag
    22321 ctggaaccac caacaatgtc atcacagaca cagctttttt acatggaact attcgtgcct
    22381 tgacacagga catgagtctc ttggtgcaaa agagggtaaa aacagttgca gaaggggttg
    22441 cagctgcctt tgatatggaa gtcgaagtgg aactcaaaca aggtggatac ctacctgttg
    22501 agaacaatcc agccttggcg cgtgaactga tggacttctt tgacgagaaa gacggaatcg
    22561 agttgattga tatcgaacct gctatgacag gcgaggactt tggttatctc ctttcaaagg
    22621 ttgatggcgt gatgttttgg ctaggtatcg atagtcccta cgctcttcat caccctcaaa
    22681 tgagtcctaa ggaagaagtc ttagctattg gggtggctgc ggtgtctagt ttcctgaaaa
    22741 agaaggcagc agaatagagg gcttgtctat gaaatcggaa ttacgcaagc aagtcttgca
    22801 tgaaatgaag gctatatctc aagagcaaaa acaggctata gaccaagctt taaccgagcg
    22861 gcttttacac catcccttct accaagaagc caaggtcatc gcaacctacc tctctttttc
    22921 tcatgagttt caaacgcggg aactgattga gcaggcgctg aaggacggca agaaggtttt
    22981 aatacccaaa acttatccca aggggcgcat ggagtttgtg gcctatgatc cgcaacagtt
    23041 ggtaaaaact tcctttgcct tactggagcc acagggagat gtggaagtgg tggatgcatc
    23101 tcagattgat ttgattcatg ttcctggtct ggcttttacg acgaaaggat atcggatagg
    23161 atacggtgga ggctattatg accgctatct ggaacatttt tctggtcgta ctttgagtac
    23221 gatatatcct tgtcaaattc aggactttat acctgaaaac catgatattc ctgttcagga
    23281 ggtattaatt gatgaaggaa atctttgata gacgttaccc tgtgacgagt ttcttcctct
    23341 tagtgacggc cttggtattt ttactaatgt tggtcactgc aggcggaaac tttgacaggg
    23401 cagatacatt atttcgattt ggagccatgt atgggccagc tattcgcctc tttcccgagc
    23461 aggtttggcg tctcttgtct gccatttttg ttcatattgg gtgggaacat ttcattgtta
    23521 atatgctttc actttattat cttggaaggc aggtagagga gattttcggt tctaagcagt
    23581 ttttctttct ctatctttta tcaggaatga tgggcaatct ctttgttttt gtatttagtc
    23641 ctaaatcctt agcagcaggc gcctctacct ctctttatgg gctatttgcc gcgattattg
    23701 ttcttcgcta tgcaactcgc aatccttata tccaacagct agggcaatcc tatctgacac
    23761 tttttgtggt taacattatt ggaagtgttc tgattccagg aatcagccta gcaggccata
    23821 tcggtggtgc agttggtggc gcatttctag cagttatctt tccagttaga ggagaaaaac
    23881 ggatgtataa caccagccag agattaggag cggtagtctt gttcgtagga ctcgccattt
    23941 tgcttttcta caagggaatg ggaatgtgac gaagttgaaa gaaaatttgt gtaatgaaaa
    24001 aagataaggc attttttgaa ccttatcttt ttattttatt ccttctcagt caattctttt
    24061 ccaagttgga tgaggtaatt cttcaaatca tctttgactt gtggatgttt gagggcgtag
    24121 tcaatagatg ttttcataaa gccaaactta tccccaacgt cgtaacgagc tcctgtaaat
    24181 tcacgggcaa aaacacgctg tgttttatta agagtatcga ttgcatcagt aagttggatt
    24241 tcatttccag caccaggagc ttggttttcg aggatttgga aaatttcagg cgtgaggagg
    24301 tagcgtccga taatagcaag gtcgctagga gcgtcctctg gagctggttt ttcaacaaag
    24361 gtttcaacac tgtaaagacc atcttttcct tcgccttgcg gagcaataac cccgtaagca
    24421 gatacttcgt catgagggac tggcatgaca gcgatagtag acgcgtgggt acgcttgtag
    24481 tcatccatga gttgtttggt aagtggaaca gccttttcgt ctgtgatatc catcaagtca
    24541 tcaccaagca taacgacaaa aggttcattt ccgacgaaag ccttggcttg caaaacagca
    24601 tctccgagac cgcgtggatg agtttggcgg ataaaatgca gacgcatgcc agttgtttca
    24661 tcaactagct tcaaaagatc tgttttccct ttttctttga ggttatattc caattcgaag
    24721 tttgaatcga agtggtcctc aatagaacgt tttgatttac cagtgacaac tagaatatct
    24781 tcaatacctg atttgagagc ctcttccacg ataaactgga tagttggttt gtctacgatt
    24841 ggcaacattt ctttggcaag ggccttggtt gctggtaaaa atcgagttcc tagtccagca
    24901 gcagggataa ctgcctttct aacttttgat gtcataaaaa tcctttctat agagggttaa
    24961 gaccactcat tttctgcttt aaattcattg ttcatgatgt cataaatggc atctttgata
    25021 ttggttccgt gataaataac ttggtaaata gcctgtgtaa tgggcatata gactccaagt
    25081 tcttgggcta gttcataggc tgctcgagtc gttgaaattc cttcgattac catgcccata
    25141 ttagcttcta tatcagctag ggattctcct cgtccgagag catctccagc tctccagtta
    25201 cgagagtgga tggaagttcc cgttacgatc aaatctccca caccagataa gccgctatag
    25261 gtcaatggac tggccccgag tgctacccct aggcgggtga tttctgctaa acctcgagcg
    25321 atgatggctg ccttagcatt atcaccaaat ccaagaccat gtaaagctcc agcaccgaca
    25381 gcaataatat ttttaagagc accagcagtt tcaaccccga taacatccgt attggtataa
    25441 agtcggaagt agtgattact aaatagctcc tgaacgtatt gagctgtttg taaatcttta
    25501 gaagcagcag ttattaaagt taggtcacgc acaatggtct cttctgcatg actaggccct
    25561 gaaacaacga cgatatcact acggagatgt tcaggaattt cttcttcaag aatggttgat
    25621 aatcgtttat ggctatcagg ttctaatccc tttgatgcgt gcatgatgat aaccttatgg
    25681 tccaaggttt gtgcaacttg ctgggcaaca agtcgtgtca cttttgttgg gacaacaaac
    25741 aaaatcgcat ccacattttt caatgtttct gctaagtcgg tgtaggcaat gatattttcg
    25801 tctagaacga catctttaaa gtagtgctta ttagtatggt gtgtattaat ttcattgatt
    25861 tgctcgggaa gatttcccca aatacgtacc tcgtgtccat tgtcatttaa gacttgtgaa
    25921 agggcggttc cccaagaacc aggccccaag acggcgacgg tttgtttttc catgatttcc
    25981 tccttgatag atttctttct tttattctat catattctag gggattttgc acttgcatta
    26041 ctggggtatg gtggaaaaat acacaaagac cgagatgaag ggataaactc ttagtcttta
    26101 gttaaagtga gaagaaatct gatagatagt ttgattcagt atatgcttat aatagaggta
    26161 aacaactcag gaagttcttg taggttgcga gagtttggcg aaaaaattaa aagattacgt
    26221 ttggctaaaa aaatcagtcg ttcagaattt tgtggtgatg agtctgaatt aagtatccgt
    26281 caattaatta gaattgaaaa tggagaatcc agaccaacac taacaaagtt aaaatatatt
    26341 gctgaacgtt tggaggttga agattacaag ttgatgccaa gttatataga gttggataag
    26401 gaatacctag aattgaagta tttcttgatg aggactccta catacgaaga tgaaactatc
    26461 gcccaaaaga aagagagtgt ttttgataag atttttgaag agtattatga taggctacct
    26521 gaggaagaaa gatttatcat cccaaattat tcatatctag cactagcgaa ctacacagtt
    26581 caaaaattac cagaaaagct agttgaaata ctgtccttct ggtgattttg cttaatttct
    26641 gatgttcgag acatgattga ggagatttgt cttgattttt tcctaaaaaa gggcagactc
    26701 ctcccttggt ttgatgctcg atttttaaaa taaggtgact tattctgtta ggcagttttc
    26761 ccctgccctc tagctctata tggaacaggg agtatcagat ttatctggca gattgtatca
    26821 aataaggctt gaaactgttt tgaataggcg tatagacttg agaatttgag aatatgtcgt
    26881 ctagcagtag agacatattt tccggcaata tgaaggaaga gacgtcgaaa acgcttgata
    26941 gtcaaggcct ttacttcatc accagctagc tgctttaaaa agaggtagag attataagcc
    27001 agacagccca tcatcatacg tacttcattc ttaatcatgg tcgaactatc tgtcttatcc
    27061 ccaaagaatc ctgctttcct ttctttgata aagttttcag cattccctcg ttcacgatag
    27121 aattgaaaca gctcctcact atctacactg cttaaattgg tcaaatgaac ttttttacaa
    27181 ccataaaaaa gagcacttaa tcgtactctt ctcttttaag gattagttga attaattcaa
    27241 atccactagt tctcctgttt ctaggtagac taggcgttca caaatgttag caatgtaatc
    27301 agcgaagcgt tccagatgcc ctatgatata aaggtattga gttccattgg gaattgaggt
    27361 ttcttggtct ttcataagtc caatgatttc ctttgataag gcataataat attggtcaat
    27421 ctgttcatct ttttgagcaa tactaatagc ttttgaggct tggtgcaaag gaaaggcaac
    27481 caataaatcg gctagcatgc tgagggataa tttacccatt tggtgtaact gttcttcgtc
    27541 aggggctagt tgattttctt ttagttgcaa aacagctttg gcaatgcctg ccatatggtc
    27601 tcccatacgt tcaaggtctg aacaagaaga catgatgcta atcacaaatc gaaggtcaga
    27661 cacttgtggc tgctgcaagg ccaacaaacg ggcacaggtc aattcgatag cgctttgacc
    27721 ttggttgata gcatgatcct tattgataat tagctctgcc atctccttgt ctttggaggc
    27781 taaggccagt aaggcttttg aagctgtttc aaggacaagt tgccctagtc ctaaaaagga
    27841 ttgttctaat tcatgcaatt ctaagtcaaa ttgatttctc ataggttttt ccttccttat
    27901 ccgaaccgtc ctgaaatata gtcttctgtg cgctgatctt ttggattggt aaacacgtca
    27961 acggtatctc caaattcgca aatttctcct gttaagaaaa aagcagtttt atctgaaata
    28021 cgtgaagctt gttgcatgtt atgggtaaca atgataatcg tataatcctt ttttagttgc
    28081 tgaatgaggt cttcaatttt taaagtggag atagggtcta aggctgaagt cggctcatcc
    28141 attaacagaa tatcaggttc tactgctaaa gctcgcgcaa tgcaaaggcg ttgctgctga
    28201 ccgccagata aggacatagc actcttttta agatcatctt tgacttcttc ccaaatggct
    28261 gcccctttta aagatttctc cactaaggca tctaattgtt ttttgtctcg aataccatgt
    28321 gtccttgggc cataagccac gttatcatag atagacatgg caaagggatt aggctgttga
    28381 aaaaccatcc ctacacgctt acgtagctga ttaaggttga atttgctact ataaatatct
    28441 tgctcatcta agaggacttg gccttcaata tggcaagaag gaaccaaatc gttcatccgg
    28501 ttaagggttt ttagaaaagt tgatttgcca caaccagatg ggcctatcaa ggcagtaatc
    28561 tgtctttctg gtaattgaat cgaaatattt tttaaggctt gaaaatcccc gtaaaataag
    28621 tctaggtgtc tgactgaaaa tgttcccata ctaggaagct cctttcacaa gttttcgaga
    28681 taataagctt gatagagtat ttatcattaa aacagtaata atcaaaatca caccggtagc
    28741 ataggcttca ttgacatgta gcccctcact tgacagcata tacatatgca gggctagaga
    28801 acgacctgaa gacatgagac tacttggcgt attggtagag gtacctaatg tatacatgag
    28861 ggcagctgtc tcaccaacga tacggccaat agctagtatc actccagcta aaatacctgg
    28921 catggcaact ggtagaacaa ttctaaaaac agtccgtaac ttacctgccc caagtccata
    28981 acttgcttga cgcatgatat cactaacaga taaaagggct tcttctgttg agcgaataat
    29041 gactggcaac accatgatga ctgaggttaa gattcctgat aacagagagt attgaaaacc
    29101 taagaagact acaaagaaga gcatgccaaa cagaccaaaa acaatggaag gaatcccaga
    29161 caaggtatct gaggccaatc gcatgatttt aacacaaagg gaatcttttt ttgtatattc
    29221 cacaagataa aaaccagcaa aaatccctat gggcaaggct aaaagaagag caccaaagac
    29281 cagaataacg gtggaaataa tcgctggcat aagggaaatg ttctcagaag tataagtcca
    29341 agaaaagagg gatagactta gatgaggtaa gcctttgatg aggataaaac caatgattaa
    29401 aaagagagag ccaaaggtta aagctgaaaa acaataaacg agaagtttta gcaggtattt
    29461 actcataaga tgattttcct ttcaagtagg caaagtaggc attaatcaag agaataagga
    29521 aaaagagaac tgctgaggtt gcaataaggg cttccctatg ctgacctgat gcgtaagcca
    29581 tttccagaac aatattggtt gttaaggttc tggttcctga aaagagtcca cttggaataa
    29641 tcggctggtt gcctgccacc aaaataactg ccatggtttc acctactgcg cgaccgattc
    29701 ctaaaataac tgctgataaa ataccagatc tcgcagctgg caagatgaca ctaaaaatac
    29761 tccgttcatg actagctcct agagccaagc taccagaata atacgttttg ggaactgttc
    29821 ggatagcaga ttctgacaaa ctgataatgg ttggcaaaat cattattcct aatagtaacg
    29881 aagcggttag gacactcatg ccatttccta aaaagcttct aatccaaggc accaataatt
    29941 gtaggccgaa aaaaccataa acaatagatg gaatggccgc catcaagttg atagctgatt
    30001 ttaagaagcc atagacgggc tttggacaat aataaaccat aaacaccgat gtcaagatgc
    30061 ctgttggcac cccaatcaca atcgctccta aggtaattaa taaggaacca acgatcattg
    30121 gtaaaatacc atagcttgcc ggaatgttcg ttggcgacca atcactgcct aataaaaaac
    30181 gggcaaagcc gtagttagcc atgaaaggta agccattact aaaaataaag aaacagatta
    30241 gcaaaatagc tacaacagct actgttgcac tcatgaaaaa aattgcccta aaaactgctt
    30301 ctttgaaggc ttgttttatc acatcttgtc ctttctagtg aagaaagtaa gggagatacg
    30361 acacctccct acttgccttc tttatcttat tgtacgatga aacgtctgca tctctttaga
    30421 gatttatgga gcaaacattt tatttaatct tgtcccaggt ggttaatttg ccactaaaaa
    30481 cgtctgcaag ttcagccata ctgacttggc ttgccttatt gtcattattg accacaacag
    30541 caataccgtc taaagcaata gcatcatggg tgagactctt accttcttca ggagttaatt
    30601 ccctagaaac cataccaata tcagcggttt tctccttaac agcggtaata cctgctgaag
    30661 acccattaga ggtaatatca atcgtaactt ctggattttc ttttttataa gcttctgcta
    30721 atttttccat taaagaagat actgaagtgg aacctacaac agacaacttg cctgataagt
    30781 gttggcttgt atattctgtg gtttcagttt tagcttcaat aaatttatta tctgtgacca
    30841 cttgttgacc ttgtttggag tggataaagc tgataaaatc ttgacctagc ttggaaagat
    30901 tagaagacca aacaatgttg aagggacgtt gaagagggta ttcaccatct aaaactgtgt
    30961 ctcgactagc cttgacacca tcaatctcta aagccttgac agatttcgtt aaagatccca
    31021 aggagatgta gccgatagca ttagcattcc cttgaactgc tgagagaaca ccttctgtac
    31081 tattttgaat cacagctgtt ttggcagtgt tgtcaatttt tttatcaccg tcttttttga
    31141 gaatccctgt gatttctgtg aaggcacccc gtgttccaga gccattttct cgtgaaatca
    31201 cctcaatcgt tcctgaagct gactgtttgg aagcagctga ctgattgcca caggcaacaa
    31261 gcccaaatcc tgataagcca atggctgcaa gagtaagcat ttttttgaat ttcataataa
    31321 tcacctttat ctctatgtat ttttcttgtg taggcttact acatttatag tctaacaagt
    31381 ctttgtaaag gtttatccct gattcatgta aagattgtgt aaagaatcaa aaaaagccac
    31441 ttttgaaaaa tggctgctcc taaaaatagc tttaaaaatt attagtcctg tgcgaaagat
    31501 tggttaggaa gaaaaatcgt gaagcaactg cctctgccaa gctgacttgt caccgtgact
    31561 tggccaccta ataattgact gagttctttg acaatggcaa ggccaagacc agtgccacca
    31621 gtttgtctgc ttcgaccttt attaactcgg taaaaacgtt caaaaatacg atcctgctct
    31681 aattgactaa taccaatccc tgtatctgat acagaaatct taatgccttc gttcaccttt
    31741 tgggtcttga cctcaatttt tcccccttgt tcagtgtaac ggatggcatt ggataaaaga
    31801 ttgagtaaga tttgggaaag taattgacta tctgatacga gggtgacatc atctggcacc
    31861 tgcaccttta gctgtaaatc cttcttcttg agctgaggtt gcaagctttg agtcaaatcc
    31921 tgtacaaatt ctgccaaaga aagggtcgtc cattgtatag gcatttgttg agccttagat
    31981 aaggtaagaa gatgctcaac aatatgctca agacgcaagc tttctttgta aataatgtct
    32041 agaaagtcat ccttgagcgc ttcttcttca gcagacatcc ccttaatggt ttcagcaaag
    32101 cccttaatcg aagtaactgg tgtcctcaat tcatgggagg catttgagac aaaggctaaa
    32161 tttaactttt cataagttct aatcgttgtt aaatcatata gcaagacgag cacagcttcc
    32221 acagattggg tggggctaaa aacgggaact gctgtcactt ctaaaatcaa gtcaccctca
    32281 tgaaacccac ttacttcttg ttttaacctt gttttttgat caaaggcttg gtgaactaaa
    32341 tttcgaatat ccatccgttt gaggtcatca agtgaactta tgtcgccgtc cacatcggga
    32401 aaataatgag gcagagagcg actggataat aacatctgac cttgagcgga aactaaaaac
    32461 gtccccatgg ttaggtgcga cagaagaacc tccattgttt cggctaggtc cttgtattgc
    32521 tgatcctgtt gggagacttt ggtttttagg ccagacacat actgagccaa agactttaag
    32581 tcttcttgcc ctttttctaa aaagtattca ctactggtca agagaggttg gtgcaaggtc
    32641 tcaaaagcaa cttcccattt ccaaaggcaa aagagccagt agccaccttg tcccaaagaa
    32701 agggctagaa gaaagagacc gatgccttta ctgatccaag ttaatgccat ccctgcaatc
    32761 agaatgaggc taacacttag attgactagc caaaattgaa ggtagcgttt catctataac
    32821 tccttgaact tataaccata accccgaatg gttcgaataa attgaggggc tttaggattg
    32881 tcttcaattt tttccctcaa cttaccaata tgaacgtcca ccaaacgtgt ttcctgccca
    32941 aagtcatacc cccagatacg ttccaaaaga cgctctctag tcagtgtcat gttgggatgt
    33001 ttcataagat agagcaagag ttcaaattct tttggggtca aactcagtaa cttattcgcc
    33061 ttgtagactt catgacgctc agggtatact ttcaaggtcc caaatagcca agaatcgtca
    33121 gcgatattat ctgaatcatc tccttcttgt tctcctttag ttcgcctgag gacagccttg
    33181 acacgcgcca gcaattctct agggctaaaa ggcttggtca ggtagtcatc agcccctaat
    33241 tccaaggcca aaaccttatc aaattcatca cttttcgcag aaaccatcat aattggagtt
    33301 ttgacgcctt tggctctcag ccgcttacaa acttccatgc catctaattg tggtaacatg
    33361 atatcaagca agataaaatc aaagggttct gtttctgcca aagctaaggc cttccgtcca
    33421 tttgttacca attgagtaga aaagccttcc ttacttaaat ggtagtcaag caatttcaga
    33481 atgtgttctt catcatccac taataagact tgttttgtca tctattatct cctattggta
    33541 acattataac acaattatca gaaatcctaa cattgctaaa tcagattaaa tttgcctatc
    33601 aagactagta tctggtcaaa cgctcaatca tctccttgtg ctctggatag gtcgccagta
    33661 gatctaccct ttcaaataat tcaaaatcct caaattcaaa accaggagca acaagacaag
    33721 aaaccagagc atcatcctta tcaactgttg atccccaaat agtgccctta ggaacacagt
    33781 agtgaagttg ttgccctttg gatatgtcca ggcctaaagt gactgcttcg tagtgaccat
    33841 ctgctgtaat catgtgaaca gtaagtgggg atcctgcatg aaaataccag atttcatctg
    33901 ctgtcaatcg gtgaaaatgt gaaggattcg tttcttctaa taagaaataa atactggtat
    33961 aaagcgccct tcccttacca gcaaggttta tagtgtctga agcttttttt gtttgtctaa
    34021 aatagccacc ttcaacatgg ggagctaact ctagagttct tatcaagtct tctttatccg
    34081 tcggagccaa tgggttgaag taactcttgt tcaaagtggt tttacgattt caagaactcc
    34141 tctcagttct gaggacacgg taatgattga tgcgacggaa gtaaaaatca atcgccctaa
    34201 aaaaagaatt agcgaatgat tctggtaaaa agaaatttca cgctatgaag gctcaagcga
    34261 ttgtcacaag tcaagggaga attgtttcta ttgccatgat atgaagttgt tcaaaatgag
    34321 ttgcagaaat atcggacaag ctggtaaaat cttggctgac agtgattatc aagggctcat
    34381 gaagatatat cctcaagcac aaactccacg taaatccagc aaactcaagc cgctaacagc
    34441 tgaagataaa gcctgtaacc atgcgctatc caaggagaga agcaaggttg agaacatctt
    34501 tgccaaagta aaaacgttta aaatgttttc aacaacctat cgaaatcatc gtaaacgctt
    34561 cggattacga atgaatttga ttgctggtat tatcaatcat gaactaggat tctagttttg
    34621 caggaagtct attatttggt taggtgaatt agtgaagtgt ttaggcaagt gtctctggtt
    34681 acgacgtcat ggcctctaaa tcgattatat ttaggggtca tgactagtga agcagttagc
    34741 tagttcgcat ataagcggct agcgtctaac aattaggaac tttagttcca ataactttaa
    34801 gattacgacg ttttaggaca taaatcgatc atatttatgt cctaaaacta gtgaagcgcc
    34861 tagccaaagt ccgaatagga tttggcgtta gttacttaga ttgctttgca atcaagtaac
    34921 tttggcgatt tacatcttct ctggcgcttc tactccaagc aagcgaaggg cttctttgag
    34981 aacgactgcg gttgcgtagc tgagggctag acggctgtcg cgttctgggc tttcatccaa
    35041 gatacgtgta tgtgcatagt atttgttaaa ggattgagcc aggctaattg caaatttagc
    35101 aatgatagaa ggttcaaagt tatctgccgc acggttgata atacgtggga agtcttgaat
    35161 gagtttaatg atttcccagc tttcagtatc attcaagcta tagttgccag ctgtttctgg
    35221 tttgaaatcg gctttgcgta agatagattg gatacgagcg taggcatatt gaacgtaagg
    35281 tccagtttca ccctcgaagg ataccatagc ttctaggtcg aagtcgtatc catttgtacg
    35341 gtcagttttg aggtcataga atttaatggc tccaacccca acagcatgtg ctacttggtc
    35401 tttgttttct agttcaggat ttttagcctc gatttggacc ttggcacggc taacagcctc
    35461 tgcaacagta ggctctagca agatgacatt ccctttacga gtagagagct tcttcccttc
    35521 ttttgtaacc agaccaaaag gaacgtgggt aatgtcgtca ctccaatcgt agcccatctc
    35581 ttgcaagaca gctttgagtt gtttaaagtg ggcagattgc tcttgaccaa cgacgtagat
    35641 agatttagca aattggtatt catttttacg gtagagggct gcagccaagt cacgtgtgat
    35701 atagagagtt gcaccatcag acttcttgat gagggctgga tgttcaattc catatttctc
    35761 aagattcaca acttgggcac cttctgattc aagaagtagt cctttttcag aaagaatgtc
    35821 tacaactgca tccatcttat cattgtagaa ggcttctccg ttatagctgt caaattcaac
    35881 cttcaattca ttgtaaaggc ggttaaattc cactaaactt tcatcgcgga accattgcca
    35941 aagagcgaga gcttcctcat ctccattttc aagtttacgg aaccattcgc gcgcttcttc
    36001 atccaagcta gggtcatttt cagcttcagc gttgatgcgg acatagagtt taaggagttc
    36061 atcgattgga tgagctttta cagcttcttc gtcgccccat tttttgtagg caacaatcaa
    36121 catcccaaat tgtttacccc agtctcccaa atggttgacc ttgaccgttt gataaccgat
    36181 tttttggaaa atatgtgaca agctatctcc gataacagtt gaacgcaggt ggccaataga
    36241 aaatggttta gcgatattcg gactagacat gtcgataaca acattttctt gtttgccaat
    36301 attttggtca gcatagtgtt ctttttcagt ggtaacagct tgcaatactt gagcagaaat
    36361 ggcagattta tcaaggaaaa agttaacgta aggtcctgtt gcgacaactt tttcaaaggc
    36421 ttggctgttc attttttcag ccagttcagc cgcaatcatt tgtggtgctt tacgttcgac
    36481 ttttgcaaga gaaaaagcag ggaaagcaat gtctcccatt tctgagtttt taggggtttc
    36541 cagtaacttt aaaatagcct cttggtccag gctatcaatg atgctagata attcgctagc
    36601 aatcaattct tttgtattca ttaagagctc ctttttggac ttttctacta ttttatcaca
    36661 attttaaaga aagaagaaaa aatttttgaa atctcctgtt tttttggtat aatatggtta
    36721 taaatatagt tataaatatg cacgcaagag gattttatga gaaaaagaga tcgtcatcag
    36781 ttaataaaaa aaatgattac tgaggagaaa ttaagtacac aaaaagaaat tcaagatcgg
    36841 ttggaggcgc acaatgtttg tgtgacgcag acaaccttgt ctcgtgattt gcgcgaaatc
    36901 ggcttgacca aggtcaagaa aaatgatatg gtgtattatg tactagtaaa tgagacagaa
    36961 aagattgatt tggtggaatt tttgtctcat catttagaag gtgttgcaag agcagagttt
    37021 accttggtgc ttcataccaa attgggagaa gcctctgttt tggcaaatat tgtagatgta
    37081 aacaaggatg aatggatttt aggaacagtt gctggtgcca ataccttatt ggttatttgt
    37141 cgagatcagc acgttgccaa actcatggaa gatcgtttgc tagatttgat gaaagataag
    37201 taaggtcttg ggagttgctc tcaagactta tttttgaaaa ggagagacag aaaatggcga
    37261 tagaaaagtt atcacccggc atgcaacagt atgtggatat taaaaagcaa tatccagatg
    37321 cttttttgct ctttcggatg ggtgattttt atgaattatt ttatgaggat gcggtcaatg
    37381 ctgcgcagat tctggaaatt tccttaacga gtcgcaacaa gaatgccgac aatccgatcc
    37441 ctatggcggg tgttccctat cattctgccc aacagtatat cgatgtcttg attgagcagg
    37501 gttataaggt ggctatcgca gagcagatgg aagatcctaa acaagcagtt ggggttgtta
    37561 aacgagaggt tgttcaggtc attacgccag ggacagtggt cgatagcagt aagccggaca
    37621 gtcagaataa ttttttggtt tccatagacc gcgaaggcaa tcaatttggc ctagcttata
    37681 tggatttggt gacgggtgac ttttatgtga caggtctttt ggatttcacg ctggtttgtg
    37741 gggaaatccg taacctcaag gctcgagaag tggtgttggg ttatgacttg tctgaggaag
    37801 aagaacaaat cctcagccgc cagatgaatc tggtactctc ttatgaaaaa gaaagctttg
    37861 aagaccttca tttattggat ttgcgattgg caacggtgga gcaaacggca tctagtaagc
    37921 tgctccagta tgttcatcgg actcagatga gggaattgaa ccacctcaaa cctgttatcc
    37981 gctacgaaat taaggatttc ttgcagatgg attatgcgac caaggctagt ctggatttgg
    38041 ttgagaatgc tcgctcaggt aagaaacaag gcagtctttt ctggcttttg gatgaaacca
    38101 aaacggctat ggggatgcgt ctcttgcgtt cttggattca tcgccccttg attgataagg
    38161 aacgaatcgt ccaacgtcaa gaagtagtgc aggtctttct cgaccatttc tttgagcgta
    38221 gtgacttgac agacagtctc aagggtgttt atgacattga gcgcttggct agtcgtgttt
    38281 cttttggcaa aaccaatcca aaggatctct tgcagttggc gactaccttg tctagtgtgc
    38341 cacggattcg tgcgatttta gaagggatgg agcaacctac tctagcctat ctcatcgcac
    38401 aactggatgc aatccctgag ttggagagtt tgattagcgc agcgattgct cctgaagctc
    38461 ctcatgtgat tacagatggg ggaattatcc ggactggatt tgatgagact ttagacaagt
    38521 atcgttgcgt tctcagagaa gggactagct ggattgctga gattgaggct aaggagcgag
    38581 aaaactctgg tatcagcacg ctcaagattg actacaataa aaaggatggc tactattttc
    38641 atgtgaccaa ttcgcaactg ggaaatgtgc cagcccactt tttccgcaag gcgacgctga
    38701 aaaactcaga acgctttgga accgaagaat tagcccgtat cgagggagat atgcttgagg
    38761 cgcgtgagaa gtcagccaac ctcgaatacg aaatatttat gcgcattcgt gaagaggtcg
    38821 gcaagtacat ccagcgttta caagctctag cccaaggaat tgcgacggtt gatgtcttac
    38881 agagtctggc ggttgtggct gaaacccagc atttgattcg acctgagttt ggtgacgatt
    38941 cacaaattga tatccggaaa gggcgccatg ctgtcgttga aaaggttatg ggggctcaga
    39001 cctatattcc aaatacgatt cagatggcag aagataccag tattcaactg gttacagggc
    39061 caaacatgag tgggaagtct acctatatgc gtcagttagc catgacggcg gttatggccc
    39121 agctgggttc ctatgttcct gctgaaagcg cccatttacc gatttttgat gcgattttta
    39181 cccgtatcgg agcagcagat gacttggttt cgggtcagtc aacctttatg gtggagatga
    39241 tggaggccaa taatgccatt tcgcatgcga ccaagaactc tctcattctc tttgatgaat
    39301 tgggacgtgg aactgcaact tatgacggga tggctcttgc tcagtccatc atcgaatata
    39361 tccatgagca catcggagct aagaccctct ttgcgaccca ctaccatgag ttgactagtc
    39421 tggagtctag tttacaacac ttggtcaatg tccacgtggc aactttggag caggatgggc
    39481 aggtcacctt ccttcacaag attgaaccgg gaccagctga taaatcctac ggtatccatg
    39541 ttgccaagat tgctggcttg ccagcagacc ttttagcaag ggcggataag attttgactc
    39601 agctagagaa tcaaggaaca gagagtcctc ctcccatgag acaaactagt gctgtcactg
    39661 aacagatttc actctttgat agggcagaag agcatcctat cctagcagaa ttagctaaac
    39721 tggatgtgta taatatgaca cctatgcagg ttatgaatgt cttagtagag ttaaaacaga
    39781 aactataaaa ccaagactca ctagttaatc tagctgtatc aaggagactt ctttgacaat
    39841 tctccacttt tttgctagaa taacatcaca caaacagaat gaaaaggagc tgacgcattg
    39901 tcgctccctt ttgtctattt tttaaggaga aagtatgctg attcagaaaa taaaaaccta
    39961 caagtggcag gccctggctt cgctcctgat gacaggcttg atggttgcta gttcacttct
    40021 gcaaccgcgt tatctgcagg aagtcttagg cgccctcctt actgggaaat atgaagttat
    40081 ttatagtatc ggggcttggt tgattggtgt ggccgtagtc ggtctagttg ctggtggact
    40141 caatgttgtc ctcgcagcct atattgccca aggagtttca tccgaccttc gggaggatgc
    40201 cttccgtaaa attcaaacct tttcttatgc tgatattgaa caatttaatg cgggaaatct
    40261 agtcgttcga atgacaaatg atatcaacca gattcagaac gttgtcatga tgaccttcca
    40321 aattcttttc agacttcccc tcttgttcat cggttcgttt atcctagcgg ttcaaacctt
    40381 accttctctg tggtgggtga ttgttctcat ggtagtcttg atttttggtt tgactgctgt
    40441 catgatggga atgatggggc ctcgttttgc taaatttcaa acccttcttg agcgcatcaa
    40501 tgccattgcc aaggaaaatt tacgtggcgt tcgtgtggtc aagtcctttg tccaagaaaa
    40561 agagcaattt gctaagttta cagaggtctc agacgagctt cttggtcaaa acctttacat
    40621 tggttatgcc ttttcagtag tggaaccctt tatgatgttg gttggttacg gggcggtctt
    40681 cctctctatt tggctggtcg cgggaatggt tcagtcggat ccgtctgttg ttggttccat
    40741 cgcttctttt gttaattacc taagccagat tatctttacc attgttatgg ttggattttt
    40801 gggaaattct gtcagccgtg ccatgatttc catgcgtcgt attcgagaaa ttcttgacgc
    40861 agagccagct atgaccttca aggatatccc agatgaagag ttggttggaa gtcttagctt
    40921 tgaaaatgtg acctttacct atccaatgga caaggaaccg atgctgaaag atgtgagctt
    40981 tactattgaa cctggtcaaa tggttggtgt agttggagcg actggtgcag gaaagtcaac
    41041 cttggctcaa ttgattccac gtctctttga tccacaggac ggggccatta aaatcggtgg
    41101 caaggatatt cgagaagtga gtgaaggaac cctgcgtaaa acagtttcca tcgttctcca
    41161 acgtgccatt ctttttagtg gaacgattgc agataacttg agacagggga aggggaatgc
    41221 tactctattt gaaatggagc gcgcagccaa tattgcccag gctagtgaat tcattcatcg
    41281 tatggagaaa acctttgaaa gtccagttga agaacgggga accaatttct ctggtggaca
    41341 aaaacaaagg atgtcgattg cgcgtgggat tgtcagcaat ccacgtattc tgatttttga
    41401 cgattcgacc tcagccttgg atgccaaatc agagcgcttg gtgcaagaag ctttgaataa
    41461 ggacttgaag gggacgacaa ccattattat tgctcaaaaa attagctcgg ttgtccatgc
    41521 agacaagatc ttggttctaa atcaaggacg attgattggt caaggcacgc atgcagactt
    41581 ggttgccaac aatgccgttt accgtgaaat ctatgaaaca cagaaatgaa agacaaacta
    41641 taagaaaagt caatagtttt atctaaacta tttcttattt caatttgatg atttggcgat
    41701 gattttagag cacggcaaaa agcccttgaa aaagtccatt ttttcaaagg taatcctgtg
    41761 ttgatttcag aaattacatc actttttgtt cgtcaaatgg cagctctttt ttaggatata
    41821 aaacagggtt cggataagtt tttttgcaag gtggatgatg gctacattgt aatgttttcc
    41881 ttattctaac ttagtcttaa gataggcctt aaaagcaggt gaaaagcgag cgcatgcttt
    41941 ggcagcttgt atgagtgcct accgcagatg aggggaaccc cgtttgatca ttcttccagc
    42001 taaatcaatc tgacctgact gataaataga agaatccagt ccagcgaaag cttgtaattg
    42061 agcaggatta tcaaaggcat gaatattttg aatctcggct aaaatgaccg cccctaaacg
    42121 attcccaatc ccagtaaccg tcgtgatgac cgaatttaac tcagccatca agtcattgac
    42181 acatttttcc gccttgtcaa tgagcctctt gtaatgtttg atgttttcat tacacgagat
    42241 aaaacgtcta tgcgttatca aactcattac caattaaaac aaatgtggtt agatcctttc
    42301 ggaaattgtc aagcgattgg aggaaatgaa ctaatccaca gcggcttatt ccaagtatac
    42361 cacttgggct ttggcagtag ctaactgcgc taaatataat ataaggagga gtaaaatgaa
    42421 gacagttcaa tttttttggc attattttaa ggtctacaag ttctcatttg tagttgtcat
    42481 cctgatgatt gttctggcga cttttgccca agccctcttt ccagtctttt ctggacaagc
    42541 ggtgacgcag ctagccaatt tagttcaagc ttatcaaaat ggcaatccag aacttgtatg
    42601 gcaaagccta tcaggaatca tggtcaatct tggcctgctg gttttggttc tatttatctc
    42661 tagtgtaata tacatgtgtc tcatgacgcg cgtgattgca gaatcgacca acgagatgcg
    42721 caaaggtctc tttggtaagc ttgctcagtt gacggtttct ttctttgacc gtcgacaaga
    42781 tggcgatatc ctgtctcatt ttaccagtga tttggataat atcctccaag cctttaacga
    42841 aagcttgatt caggtcatga gcaatattgt tttatacatt ggtctgattc ttgtcatgtt
    42901 ttcgagaaat gtgacgctgg ctctcatcac cattgccagc accccattgg ctttccttat
    42961 gctgattttc atcgtgaaaa tggcacgcaa atacaccaac ctccagcaga aagaggtagg
    43021 gaagctcaac gcctatatgg atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg
    43081 aattcaagag gatatgatgg caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac
    43141 ctttaaagga agaatgttct caggaattct tttccctgtc atgaatggga tgagcctgat
    43201 taatacagcc atcgtcatct ttgctggttc ggctgtactt ttgaatgata agtctattga
    43261 aacaagtaca gccctaggtt tgattgttat gtttgcacaa ttttcacagc agtactacca
    43321 gcctattatc caagttgcag cgagttgggg aagccttcag ttggccttta ctggagctga
    43381 acgaattcag gaaatgtttg atgcagagga ggaaatccga cctgaaaagg ctccaacctt
    43441 cactaagttg caagaaagtg ttgaaatcag tcatatcgat ttttcatact tgcctgataa
    43501 acctattttg aaagatgtca gcatttctgc ccctaaaggc cagatgacag cagttgttgg
    43561 gccgacaggt tcaggaaaaa cgactattat gaacctcatc aatcgctttt atgatgttga
    43621 tgctggtggt atttattttg atggtaaaga cattcgtggc tatgacttag atagtcttag
    43681 aagcaaggtg ggaattgtat tgcaagattc ggtcttgttt agcggaacga ttcgagacaa
    43741 tatccgattt ggtgtgccag atgctagtca ggaaatggtt gaggtagcag caaaagcaac
    43801 ccacattcac gactatatcg aaagtttgcc tgataagtac gatactctta ttgatgatga
    43861 ccagagcatc ttttcaacag ggcagaagca attgatttca atcgctcgaa ccctgatgac
    43921 agatccagaa gttctcattc tcgatgaagc aacttcaaac gtagatacgg tgacagaaaa
    43981 caagattcag catgccatgg aggtggttgt agcaggtaga actagtttcg tcattgccca
    44041 ccgcttgaaa accattctca atgcagatca gattattgtc cttaaagatg gagaagtcat
    44101 tgaacgtggt aaccaccatg aacttttgaa gctaggtggc ttttattcag aactctatca
    44161 caatcaattt gttttcgaat aagaaagaag ttgtcctatg tgggcagctt tttcttgtcc
    44221 ataaaaaatg tttatcacag ccttaaaaaa aacatattag acgaaagtca ttttgagtga
    44281 tatgatagga ctatcgttag cattcgaaag gagaggcatc atggctagaa cggttgtagg
    44341 agttgctgca aatctatgtc ccgtagacgc agaaggcaaa atcattcatt catctgtatc
    44401 ttgtagattc gcagagatca ttcgtcaaat cggtggtctc cctttagtca ttcctgttgg
    44461 tgatgagtca gttgtacgtg attatgtgga aatgattgac aaactcattt tgacaggagg
    44521 ccaaaatgtt catcctcagt tttatggaga gaaaaagacc gtcgagagcg atgattacaa
    44581 tctggtccgt gacgaatttg aattggcact cttgaaggaa gcgcttcgtc agaataaacc
    44641 aattatggca atctgtcgcg gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa
    44701 tcaagaaatc gaaggtcact ggcaaggact acctttcggg acatctcact ctattgagac
    44761 agtagaagga agcgtggtgg ctaagctatt tgggaaagaa agtcaggtca actcagtcca
    44821 tcgtcaaagc attaaagatt tggcacctaa tttccgtgta actgctattg attcaagaga
    44881 ccaaactatt gaagcgattg agtctatcga cgagcaccgc attatcggtt tacagtggca
    44941 tccagagttt ctggttaatg aagaagatgg caatttagaa ttatttgagt atttattgaa
    45001 tgaactgtaa cgattggaac atctggtcgt tctttctttt attttttcaa aatttttaga
    45061 atgtggcatt ttacgcaaac gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa
    45121 acttgaaaaa aacgaaggta agcgttatga tagaaaagaa gaaatattgg aggaagaaca
    45181 tgtcacatat taaatttgat tattcaaaag ttttagacaa atttgttgca ccacatgaag
    45241 tggaatacat gcaatcacaa gtaacagcag cagatgaatt gatccgtaaa ggaactggtg
    45301 ctggtagcga cttcttggga tggttggacc ttcctgaaaa atacgatcgc gaagaatttg
    45361 accgcatctt gaaagctgct gagcaaatca agtcagacag cgatgttttg gttgtgatcg
    45421 gtattggtgg atcttacctt ggtgcaaaag cagcaatcga cttcttgaat caccattttg
    45481 ctaacttgca aacaaaagaa gaacgcaaag ctccacaaat cctttacgca ggaaactcaa
    45541 tctcatctac ttaccttgct gacttggtag agtatgttgc agacaaagac ttctcagtaa
    45601 acgtaatttc taaatcaggt acaacaactg aaccagcgat tgctttccgt gtctttaaag
    45661 aactcttggt taagaaatac ggtcaagaag aagctaacaa acgtatctat gcaacaactg
    45721 accgccaaaa gggtgctgtt aaggttgaag cagacgctaa cggttgggga acatttgttg
    45781 ttccagatga tatcggtgga cgcttctcag tattgacagc cgttggtttg cttccaatcg
    45841 cagcatcagg agctgacatc aaagctctta tggaaggtgc gaatgcagct cgcaaagact
    45901 acacttcaga caaaatctct gaaaacgaag cttaccaata cgcagctgtt cggaacatcc
    45961 tttatcgtaa aggctatgca actgagatct tggtaaacta tgagccatca cttcaatact
    46021 tctcagaatg gtggaaacaa ttggctggtg aatcagaagg aaaagaccaa aaaggtatct
    46081 acccaacttc agccaacttc tcaactgact tgcactcact tggtcaattt atccaagaag
    46141 gaactcgtat catgtttgaa acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta
    46201 ttcctacttt ggaagaagac cttgacggac ttggttacct tcaaggaaaa gacgttgact
    46261 ttgtaaacaa aaaagcaact gacggtgttc ttcttgccca cacagatggt gatgtaccaa
    46321 acatgtatgt gactcttcca gagcaagacg ctttcactct tggttacact atctacttct
    46381 tcgaattggc aattgccctt tcaggttact tgaatgctat caacccattt gaccaaccag
    46441 gtgttgaagc ttataaacgt aacatgtttg cccttcttgg aaaaccagga tttgaagaat
    46501 tgagcaaaga acttaacgca cgtctataat agaagaaaag agtggtttgc ccactctttt
    46561 tactctcttt atccatagaa attggactca gccaagactt gtgatataat atagaaagca
    46621 aaaaggcaga cgcctagata ataggagaaa ctatgtcaaa agatatccgc gtacgttacg
    46681 caccaagtcc aacaggacta ctacacatcg gaaatgctcg tacagcattg tttaattact
    46741 tgtattcgcg ccatcatggt ggaacatttc tcatccgtat cgaagatact gaccgtaaac
    46801 gccatgtcga ggatggtgaa cgttcacaac ttgaaaacct tcgctggtta ggcatggatt
    46861 gggatgaaag tccagaatca catgagaatt atcgccagtc tgagcgtttg gacttgtatc
    46921 aaaaatacat tgaccaacta ttagctgaag gaaaagccta taaatcttac gttacagaag
    46981 aagagttggc agctgaacgc gaacgccaag aagtagctgg cgaaacacca cgctacatca
    47041 atgaatacct tggtatgagt gaagaagaaa aagcagctta catcgcagaa cgtgaagcag
    47101 cagggatcat cccaactgtt cgtttggctg tcaatgagtc aggtatctac aagtggcatg
    47161 atatggtcaa aggcgatatc gaatttgaag gtggcaatat cggtggtgac tggattatcc
    47221 aaaagaaaga cggttaccca acttacaact ttgccgttgc catcgatgac catgatatgc
    47281 aaatctctca tgttatccgt ggagacgacc atattgctaa cacaccaaaa cagctcatgg
    47341 tttatgaagc acttggttgg gaagctccag agtttggtca catgaccttg attatcaact
    47401 ctgagactgg taagaagtta tctaaacgtg atactaatac acttcaattt atcgaagatt
    47461 accgaaagaa aggttacctt ccagaagcag tctttaactt tattgctctt cttggttgga
    47521 acccaggtgg tgaagatgag attttctctc gtgaagaact cattaaactt tttgatgaaa
    47581 accgcctcag caagtcacca gcagcctttg atcagaaaaa actagactgg atgagcaatg
    47641 attatatcaa gaatgcagac cttgaaacca tctttgaaat ggcaaaacca ttcttagagg
    47701 aagcaggccg tttgactgac aaggctgaaa aattagttga gctctataaa ccacaaatga
    47761 aatcagtaga tgagattatc ccattgacag atcttttctt ctcagatttc ccagaattga
    47821 cagaagcaga gcgcgaagtc atgacgggtg aaacagttcc aacagttctt gaagcattca
    47881 aagcaaaact tgaagcgatg acagatgata aatttgtgac agaaaatatc ttcccacaaa
    47941 ttaaagcagt tcaaaaagaa acaggtatta aagggaaaaa tcttttcatg cctattcgta
    48001 tcgcagtttc aggcgaaatg catgggccag aattaccaga tacaattttc ttgcttggac
    48061 gtgaaaaatc aattcagcat atcgaaaaca tgctaaaaga aatctctaaa taaagaggat
    48121 acaataatgg acatctggga aaagatgtac gaagaagcac agaaactata caatccacat
    48181 gaagtatcag actttgttta tgccaatcat gttgtagctg cagtagaagc agaagatgga
    48241 caaatattta caggattctg tatggaggga acctgtggtg ttttccatct ctgcgcagaa
    48301 cgggcggccc tcttcaatat gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta
    48361 gcctttcgag acaaaccacc ttatggtgga agttcagcca tgccttgcgg tgcttgtaga
    48421 gaattccttt tagagcttaa tgctgaaaat aaagatgcag aattcatgat ggactataat
    48481 ataagaaaaa cagttaaagt cgcagaacta atcccttatt ggtggggaga agaacgtgct
    48541 tctaagttta atgagcgata gaagagtcag tataattctg gcttttttta ctataagttg
    48601 aaaaaat
//
LOCUS       DAVIME010000009        48481 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVIME010000009 DAVIME010000000
VERSION     DAVIME010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.009"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(16..657)
                     /gene="plsY"
                     /locus_tag="VV588_000565"
     CDS             complement(16..657)
                     /gene="plsY"
                     /locus_tag="VV588_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU7082951.1"
                     /translation="MITIILLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            793..2736
                     /gene="parE"
                     /locus_tag="VV588_000566"
     CDS             793..2736
                     /gene="parE"
                     /locus_tag="VV588_000566"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU7082952.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3156..5627
                     /gene="parC"
                     /locus_tag="VV588_000567"
     CDS             3156..5627
                     /gene="parC"
                     /locus_tag="VV588_000567"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU7082953.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            5757..6779
                     /locus_tag="VV588_000568"
     CDS             5757..6779
                     /locus_tag="VV588_000568"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU7082954.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            6835..7539
                     /locus_tag="VV588_000569"
     CDS             6835..7539
                     /locus_tag="VV588_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7082955.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            7604..8293
                     /locus_tag="VV588_000570"
     CDS             7604..8293
                     /locus_tag="VV588_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU7082956.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8290..9213
                     /locus_tag="VV588_000571"
     CDS             8290..9213
                     /locus_tag="VV588_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU7082957.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9228..9872
                     /gene="pcp"
                     /locus_tag="VV588_000572"
     CDS             9228..9872
                     /gene="pcp"
                     /locus_tag="VV588_000572"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU7082958.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10040..10270
                     /locus_tag="VV588_000573"
     CDS             10040..10270
                     /locus_tag="VV588_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU7082959.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10320..10400
                     /locus_tag="VV588_000574"
     tRNA            10320..10400
                     /locus_tag="VV588_000574"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10354..10356,aa:Tyr,seq:gta)
     gene            10410..10481
                     /locus_tag="VV588_000575"
     tRNA            10410..10481
                     /locus_tag="VV588_000575"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10442..10444,aa:Gln,seq:ttg)
     gene            10643..11845
                     /gene="rpsA"
                     /locus_tag="VV588_000576"
     CDS             10643..11845
                     /gene="rpsA"
                     /locus_tag="VV588_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU7082960.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(11931..12299)
                     /locus_tag="VV588_000577"
                     /pseudo
     CDS             complement(11931..12299)
                     /locus_tag="VV588_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12547..13044
                     /locus_tag="VV588_000578"
     CDS             12547..13044
                     /locus_tag="VV588_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU7082961.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            13044..14699
                     /gene="dnaX"
                     /locus_tag="VV588_000579"
     CDS             13044..14699
                     /gene="dnaX"
                     /locus_tag="VV588_000579"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU7082962.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14727..14921
                     /locus_tag="VV588_000580"
     CDS             14727..14921
                     /locus_tag="VV588_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU7082963.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            15071..15841
                     /gene="sufC"
                     /locus_tag="VV588_000581"
     CDS             15071..15841
                     /gene="sufC"
                     /locus_tag="VV588_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU7082964.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15869..17131
                     /gene="sufD"
                     /locus_tag="VV588_000582"
     CDS             15869..17131
                     /gene="sufD"
                     /locus_tag="VV588_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU7082965.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            17142..18368
                     /locus_tag="VV588_000583"
     CDS             17142..18368
                     /locus_tag="VV588_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU7082966.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18355..18795
                     /locus_tag="VV588_000584"
     CDS             18355..18795
                     /locus_tag="VV588_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU7082967.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18849..20261
                     /gene="sufB"
                     /locus_tag="VV588_000585"
     CDS             18849..20261
                     /gene="sufB"
                     /locus_tag="VV588_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU7082968.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYRNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20492..21733)
                     /locus_tag="VV588_000586"
     CDS             complement(20492..21733)
                     /locus_tag="VV588_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU7082969.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21836..22945
                     /locus_tag="VV588_000587"
     CDS             21836..22945
                     /locus_tag="VV588_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU7082970.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23479..23826
                     /gene="ssrA"
                     /locus_tag="VV588_000588"
     tmRNA           23479..23826
                     /gene="ssrA"
                     /locus_tag="VV588_000588"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23999..24086)
                     /locus_tag="VV588_000589"
     tRNA            complement(23999..24086)
                     /locus_tag="VV588_000589"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24050..24052),aa:Ser,seq:gga)
     gene            24249..24989
                     /locus_tag="VV588_000590"
     CDS             24249..24989
                     /locus_tag="VV588_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU7082971.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24986..25897
                     /gene="pfkB"
                     /locus_tag="VV588_000591"
     CDS             24986..25897
                     /gene="pfkB"
                     /locus_tag="VV588_000591"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU7082972.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25894..27846
                     /locus_tag="VV588_000592"
     CDS             25894..27846
                     /locus_tag="VV588_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7082973.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            28010..30235
                     /locus_tag="VV588_000593"
     CDS             28010..30235
                     /locus_tag="VV588_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU7082974.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKTLLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30280..30708)
                     /locus_tag="VV588_000594"
     CDS             complement(30280..30708)
                     /locus_tag="VV588_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082975.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30846..31988
                     /locus_tag="VV588_000595"
     CDS             30846..31988
                     /locus_tag="VV588_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU7082976.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31997..33211
                     /gene="thiI"
                     /locus_tag="VV588_000596"
     CDS             31997..33211
                     /gene="thiI"
                     /locus_tag="VV588_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU7082977.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33346..34169
                     /locus_tag="VV588_000597"
                     /pseudo
     CDS             33346..34169
                     /locus_tag="VV588_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            34191..34930
                     /locus_tag="VV588_000598"
                     /pseudo
     CDS             34191..34930
                     /locus_tag="VV588_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34943..36109
                     /locus_tag="VV588_000599"
     CDS             34943..36109
                     /locus_tag="VV588_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU7082978.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36617..38110
                     /locus_tag="VV588_000600"
     CDS             36617..38110
                     /locus_tag="VV588_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU7082979.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            38123..39188
                     /locus_tag="VV588_000601"
                     /pseudo
     CDS             38123..39188
                     /locus_tag="VV588_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            39248..39484
                     /locus_tag="VV588_000602"
     CDS             39248..39484
                     /locus_tag="VV588_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU7082980.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            39481..39894
                     /locus_tag="VV588_000603"
     CDS             39481..39894
                     /locus_tag="VV588_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU7082981.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            40012..40977
                     /locus_tag="VV588_000604"
     CDS             40012..40977
                     /locus_tag="VV588_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU7082982.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            41000..41581
                     /locus_tag="VV588_000605"
     CDS             41000..41581
                     /locus_tag="VV588_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU7082983.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            41611..44961
                     /locus_tag="VV588_000606"
     CDS             41611..44961
                     /locus_tag="VV588_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU7082984.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYKKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEQY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            45232..45432
                     /locus_tag="VV588_000607"
     CDS             45232..45432
                     /locus_tag="VV588_000607"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7082985.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHIYGKATLTRIEEIFEEYKSS"
     gene            complement(45549..46019)
                     /locus_tag="VV588_000608"
     CDS             complement(45549..46019)
                     /locus_tag="VV588_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU7082986.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(46036..48309)
                     /locus_tag="VV588_000609"
     CDS             complement(46036..48309)
                     /locus_tag="VV588_000609"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU7082987.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQIFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQNKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT        14862 a         8607 c        10631 g        14381 t
ORIGIN      
        1 cacagaactg gcattttatt ttttaggatc ttgatgggtt aggttcaatc cccaagggac
       61 caaattttca gttttatttt tgatacgagc tatattgtcc ttatgacgaa tgataatcaa
      121 actagcaagt gctaagataa tagcgatgaa gagagagtca tagttactca ggataaaacc
      181 aaaaagtgga aagagcagaa ccccgataac agccgcgatc gatgctgtga cactagacag
      241 tgaaatcata ctgccaagat agagagctcc aaagaagata atcgcaaggt agagacagaa
      301 gataggcgca aatccgaaaa tcactccagc actggttgcg acagccttac cacctttaaa
      361 tcctgcaaag atagggaagg tatggccgat aacagccaaa agtccaaaga tgagaggaga
      421 aacgccttgt agatgaaaaa taatcggaag cagcgttgct agggttcctt tgaaaaagtc
      481 aatcacaaag gttgccatac cagctttctt acctaaaatg cggaaggtat tggtcgttcc
      541 agtgttacca gaaccatgct cgcgtagatt gatttgaaag aatacttgtc caatccagag
      601 accagatgga atcgaaccca gcagataggc taggattaat aaaattattg taatcatact
      661 cctattatat catgaattgg gaaagaaaag cagagaatct ctgctgaaat tgtcacatcg
      721 gagaaagaaa aattttgcaa aatccttgga aaacctgtag aatagtaaag atgaacgaat
      781 aggaggttcc ttgtgtcaaa aaaggaaatc aatattaaca attataatga tgatgctatt
      841 caggtgctag aagggttgga tgcggtccga aaacgtccag ggatgtatat tggatcgacc
      901 gatggcgctg gtcttcatca cctagtttgg gaaatcgttg ataatgcagt cgatgaagcc
      961 ttgtctgggt ttggtgatcg tattgatgta actatcaata aagacggtag tctaacggtt
     1021 caagaccatg gacgtgggat gccgacaggt atgcacgcta tgggaattcc aactgttgag
     1081 gttatcttta ccattcttca tgccggaggg aaattcggtc aaggtggcta taagacatca
     1141 ggtggacttc acggagtggg ttcttccgtt gttaacgccc tttctagctg gttagaagtt
     1201 gaaattaccc gtgatggcgc agtttacaag caacgttttg aaaatggtgg aaaacctgtc
     1261 acgactttga agaaagtcgg tacagcaccc aagtctaaaa caggcaccaa agttactttt
     1321 atgcctgacg cgactatctt ttctacgaca gatttcaagt acaataccat ttcagagcgc
     1381 cttaatgaat cagcctttct cttgaaaaat gtgaccttgt ctttaacgga caagcgaaca
     1441 gatgaagcga ttgagttcca ctatgagaat ggagtacaag attttgtttc ttatctcaac
     1501 gaagataagg aaatcttgac gccagttctt tactttgaag gggaagacaa tggttttcaa
     1561 gtggaagtag ccctccagta caatgacgga ttctcagata acattctatc ctttgtcaat
     1621 aacgttcgca ccaaggacgg tggaacgcac gagacaggac tcaagtctgc cattaccaag
     1681 gtcatgaatg actatgcacg taaaacaggt cttctcaagg aaaaagataa aaaccttgaa
     1741 ggttcagact atcgtgaggg actagcggcc gttctttcta tcttagttcc tgaagaacac
     1801 ttgcagtttg aaggacagac caaggataaa ctaggaagcc ccctagctcg cccagttgtg
     1861 gatggaatag tggctgataa gttgaccttt ttccttatgg aaaatgggga attagcttct
     1921 aacctcatcc gcaaggctat caaggcccgt gatgctcgtg aagcagcacg taaggcgcgt
     1981 gatgagagcc gaaatgggaa gaaaaacaag aaagataagg gcttgttgtc tgggaaattg
     2041 accccagccc aatctaagaa tcctgctaag aatgaactct atctagttga gggggactct
     2101 gccggtggtt ctgccaaaca aggtcgtgac cgcaagttcc aggctattct acctcttcgt
     2161 ggtaaggtta tcaatacagc caaggccaag atggcggata tcctcaaaaa tgaagagatc
     2221 aataccatga tttataccat tggtgcgggt gttggagcag acttctctat tgaagatgcc
     2281 aactatgata agatcattat catgaccgat gcggataccg acggtgccca tatccagacc
     2341 ttgctcttga catttttcta ccgttacatg cgtccgctag tcgaggcagg tcatgtctat
     2401 attgccctcc cacctcttta caagatgtcc aaaggtaaag gcaagaaaga agaagtggcc
     2461 tacgcttgga cggacggaga actagaagaa ctccgtaaac agttcggtaa aggcgctacc
     2521 ctccaacgat acaaaggact tggtgagatg aatgcggacc agctctggga aacaaccatg
     2581 aacccagaaa cacgtaccct catccgtgtc acaattgaag atttagcgcg cgccgaacgc
     2641 cgcgtcaatg ttctcatggg agataaggta gaaccacgcc gtaaatggat tgaagataat
     2701 gtcaagttta cgctagaaga agcgacagtg ttttaatgaa agaaaataat atgttagtaa
     2761 actggaaatt agagtcggat gtgaatgact atgtgaaaaa gcagtttgaa aatcttggtt
     2821 tgaaaaaatt gcaggattat taatgaagaa tctgctatga gtgcttatct taaagaggcg
     2881 cttaagggag cggttaagac acaaactaag actaattttg gaaaaccaga ttttcatatt
     2941 gaaaaataca aacaggatag tttggttact tatcgtaact gaacacggga cgaattcccg
     3001 taaaatatct tttactgcat aaaaacctac tctacattct ttgaaaggag ttgaacacgc
     3061 cctagatact gtgtgaaaaa gataaattct cttgtgagtt tgcttacttc aagaattttc
     3121 tattttcact tggtatttta tgggctttgt atcttatgtc taacattcaa aacatgtccc
     3181 tggaggacat catgggagag cgctttggtc gctactccaa gtacattatt caagaccggg
     3241 ctttgccaga tattcgtgat gggttgaagc cggttcaacg ccgtattctt tattctatga
     3301 ataaggatag caatactttt gacaagagct accgtaagtc ggccaagtca gtcgggaaca
     3361 tcatggggaa tttccaccca cacggggatt cttctatcta tgatgccatg gttcgtatgt
     3421 cacagaactg gaaaaatcgt gagattctag ttgaaatgca cggtaataac ggttctatgg
     3481 acggagatcc tcctgcggct atgcgttata ctgaggcacg tttgtctgaa attgcaggct
     3541 accttcttca ggatatcgag aaaaagacag ttccttttgc atggaacttt gacgatacgg
     3601 agaaagaacc aacggtcttg ccagcagcct ttccaaacct cttggtcaat ggttcgactg
     3661 ggatttcggc tggttatgcc acagacattc ctccccataa tttagctgag gtcatagatg
     3721 ctgcagttta catgattgac cacccaactg caaagattga taaactcatg gaattcttac
     3781 ctggaccaga cttccctaca ggggctatta ttcagggtcg tgatgaaatc aagaaagcct
     3841 atgagactgg gaaagggcgc gtggttgttc gttccaagac tgaaattgaa aagctaaaag
     3901 gtggtaagga acaaatcgtt attactgaga ttccttatga aatcaataag gccaatctag
     3961 tcaagaaaat cgatgatgtt cgtgttaata acaaggtagc tgggattgct gaggttcgtg
     4021 atgagtctga ccgtgatggt cttcgtatcg ctattgaact taagaaagac gctaatactg
     4081 agcttgttct caactactta tttaagtaca ccgacctaca aatcaactac aactttaata
     4141 tggtggcgat tgacaatttc acacctcgtc aggttgggat tgttccaatc ctgtctagct
     4201 acatcgctca ccgtcgagaa gtgattttgg cgcgttcacg ctttgacaaa gaaaaggctg
     4261 agaaacgtct ccgtatcgtc gaaggtttga ttcgtgtgat ttcgattttg gatgaagtca
     4321 ttgctcttat ccgtgcttct gagaataagg cggacgccaa ggaaaacctc aaagttagct
     4381 atgattttac ggaagaacag gctgaggcta tcgtaacttt gcaactgtac cgtttgacca
     4441 ataccgatgt ggttgtcttg caggaagaag aagcagagct tcgtgagaag attgctatgc
     4501 tggcggctat tatcggtgat gaaaggacta tgtacaatct catgaagaaa gaacttcgtg
     4561 aggtcaagaa gaactttgca actcctcgtt tgagttcttt agaagacact gcgaaagcaa
     4621 ttgagattga tacagctagt cttatcgctg aggaagatac ctacgtcagc gtgaccaagg
     4681 caggttacat caagcgtacc agtccacgtt cctttgcggc ttccaccttg gaagaaattg
     4741 gcaagcgtga tgatgaccgt ttgatttttg ttcaatctgc caagacaacc cagcacctct
     4801 tgatgttcac aagtcttgga aatgtcatct acagaccaat ccatgagttg gcagatattc
     4861 gttggaagga catcggagag catctgagcc aaaccatcac aaactttgaa acgaatgaag
     4921 caatccttta tgtggaagta ctggatcagt ttgacgatgc gacaacctac tttgcagcga
     4981 ctcgccttgg tcaaatcaaa cgggtagagc gaaaagaatt cactccatgg cggacctata
     5041 gatctaagtc tgtcaagtat gctaagctca aagacgatac agatcagatt gtagcagtgg
     5101 ctccgattaa actagatgat gttgtcttgg ttagtcaaaa tggttatgcc ctgcgtttca
     5161 atatcgaaga ggttccggtt gtcggtgcta aggcagcagg tgtcaaggct atgaatttga
     5221 aagaagatga tgtcctccaa tctggcttta tctgtaatac ttcgtccttc tacctcttga
     5281 cccagcgtgg aagcttgaaa cgtgtttcca ttgaggaaat tctagcaacc agccgtgcca
     5341 aacgaggatt acaagtcttg cgtgagttga aaaacaaacc gcatcgtgtc ttcttggcag
     5401 gagcagttgc agagcaagga tttgttggcg atttcttcag tacggaagtg gatgtgaacg
     5461 accaaactct gcttgtccaa tccaataaag gaacaatcta tgaaagccga ttgcaagact
     5521 tgaacttgtc agaacgcact agcaatggaa gcttcatttc tgacacgatt tcagatgaag
     5581 aagtttttga cgcttatctt caggaagtag ttactgaaga taaataagtg aaatgaagaa
     5641 tcagttctaa gatggttttt attggaggaa ttttctgaaa attacaaaat atacttgcta
     5701 ttttagaaaa atagtgtaga atataagaaa taggttttta gaataaggag tggaatatga
     5761 cagtaacgat tgattgggaa aacctcggtt tttcctatat gaaattacct tatcgctatc
     5821 ttgctcattt caaaaatgga caatgggatc aaggagagct tacagaggat gcaactttgc
     5881 atatttcaga gtcttctcca agtcttcact atggacaaca agcatttgaa ggtttgaaag
     5941 cttatcgtac taaggatggc agtgttcaac tgttccgtcc tgatgaaaat gctaaacgcc
     6001 tgcaacgtac atgtgaccgt ctcttgatgc cacaagttcc gacagacatg tttgtagaag
     6061 cttgtaaagc agttgtccgt gcgaatgaag aatacgtacc accatacgga ataggtggaa
     6121 ccttatatct tcgccctctt ttgattggtg tcggagatat tatcggggta aaaccggcag
     6181 aagagtacat tttcaccatc tttgctatgc cagttggaaa ttactttaaa ggtggtttgg
     6241 tcccaaccaa cttcttgatt caggatgagt acgaccgtgc agcaccaaat ggtacaggtg
     6301 cggctaaggt tggtggaaac tatgctgcaa gtctcttacc aggaaaaatg gccaagtcac
     6361 gccatttctc agatgttatc tatctggacc catcaactca tacaaagatt gaagaagtcg
     6421 gatcagctaa tttctttgga attacagctg ataatgaatt tgtaacacca ttgagtccat
     6481 ctatcttgcc atctattacc aagtattcct tgctttattt ggcagaacat cgcttgggat
     6541 taactcctat tgagggtgat gttccaattg ataatcttga ccgttttgta gaggcaggtg
     6601 cctgtggtac agcagcggtt atttctccaa ttggaggtat tcaacatggt gatgatttcc
     6661 atgtattcta tagtgaaaca gaagtaggtc ctgtgacgcg taaattatat aatgaattga
     6721 cgggtattca gtttggcgat attgaagcgc cagaaggttg gattgtaaaa gtagattaaa
     6781 ataaaccaaa ggagattttt tatgaaatag aaaaagtggc tcttaacagc aggagtggtc
     6841 ctgagcacgt tagctatttt agtggcttgt ggaaaaactg ataaagaagc agatgcaccg
     6901 acaacatttt cttatgtcta tgcagtagat ccagcatcat tgggctacag tataacgact
     6961 cgaacatcga cgacagacgt tattggaaat gttattgatg gtttgatgga aaatgataaa
     7021 tacggcaatg ttgctccttc tcaaaaagac tatgatttga atagtacagg atgggctcca
     7081 agctatcaag atccagcgtc ttacttgaat attatggatc caaaatctgg ttctgccatg
     7141 aaacaccttg gtattacgaa aggaaaagat aaggatgttg tagctaaacc tggtttggat
     7201 aaatataaga aattgttaga agatgctgtt tctgagacca ctgacctaga gaagagatat
     7261 gaaaaatatg ccaaagctca agcttggtcg acagatagtt cattattgat gccaacagct
     7321 tcatctggtg gttctccaat tgtaagtaac gtagtaccat tctcaaaacc atactcacaa
     7381 gttggtatta agggggaacc atatatcttt aaaggaatga aattgcaaaa agatattgtt
     7441 acaacaaaag aatataacga ggtttttaaa aaatggcaaa aagaaaaatt ggaatccaat
     7501 agcaaatacc aaaaagaact agaaaaacac attaaataag gaatggtatt gatcttgata
     7561 aaatttttaa aatactgtca ttttgaatat aaaggagttt gatatggagt ggattagatt
     7621 aataggaata gcaatcattg ttgtgggttt tattttaaaa tttgatacaa ttgcaacagt
     7681 agtcttagct ggtttggtta cagctttagt ttcaggtgtt tctctcgttg aatttttgga
     7741 gattttggga aaagaattta gcaatcagcg agtgctcacg atttttatgg ttaccttgcc
     7801 tcttgtgggg ctgtcagaaa cctttggact caagcaacga tcaatcgatt tgattcgaaa
     7861 gattaaaggt ctgacagttg gaaacttcta tacagtttat ttctttattc gagagttagc
     7921 tggtttcttt tcaattcgtc taggaggaca ccctcagttt gtcagacctt tggttcaacc
     7981 tatgggagaa gcagctgcag agtctcaatt aggtagaaag ttaacagagg ttgaagatga
     8041 gacaataaaa gcgcgtgcgg ctgcgaatga aaattttgga aatttctttg ctcaaaatac
     8101 gtttgtaggt gctgggggag tcctcttgat agggggaaca ttagatcagt taggctatga
     8161 aagcaattat gcagggattg cttctacatc tattattgtt gctgttataa cacttattgt
     8221 agtggggatt tacaattatt tatttgataa aaaattgata tcaaaaaaga ctaggggagg
     8281 agaacaaaaa tgacagagtt ggcaaagcaa ctattagagt tgacctatat tgtgattggt
     8341 tgtcaatttc tccatacagc ctattgtagt tataaagata aaacaaaccc agttcgactt
     8401 gggacatctg cattttggac tctattgtct attacgttta taggtggttc ctatatgcca
     8461 aatatgagta ttggtattat tgtaatccta ttatcgctgt taacattgtt taagcaagtc
     8521 cgtatcggaa ccttgccatc cttagatgaa atgaaagcca atattgaatc taacaggttg
     8581 aaaaataaaa tttttattcc agttatgctg atggcaatac ttgcgttggt cttagcgcaa
     8641 atgattccag aatttagcaa gatttcgatt agccttgccg ccttgtttgc tacaatttct
     8701 gttcttgtga ttaccaatag tcaccctaag agtctgttat cagaaaataa tcgaatgact
     8761 cagcaagttt caacaagtgg gattgttcct caattattag gggctttggg ggctattttt
     8821 actgtagcag gtgttggtga tgttatctct catctgatta gcggtattgt tccttcagat
     8881 agtcgcttta taggagtttt ggcctatgtt cttggaatgg ttctattcac aatgattatg
     8941 ggaaatgctt ttgcagcatt caccgttatt acagcaggtg ttggagttcc cttcgtattt
     9001 gctctgggag ctaatccaat tgtggctggt gctcttgcca tgacagcagg ttattgtggg
     9061 accttattga ccccaatggc tgctaatttt aacgctctac cagcagcatt gatggatatg
     9121 aaagatcaga atggcgttat aaaggctcaa gcaggtgttg ctctagtaat gattgttatt
     9181 cacatattct taatgtactt tctcgcattt tagtaaagga aaataaaatg aaaatattgg
     9241 ttacaggttt taatcctttt ggaggtgaaa agattaatcc agctttggag gctgtaaaat
     9301 tattaccatc tgagattaat ggggctgaag ttcgctgggt agaaattcca acggtttttt
     9361 ataagtcgtc agaagtttta gaggcagaaa tattacgata tcaaccagat gctgtacttt
     9421 gtattggaca agcaggcggc aggaccggct taacacctga acgagtggct attaatcaag
     9481 atgatgctcg catacctgat aacgaaggca atcaaccaat tgatacaccg attcgtattg
     9541 atggagcatc ggcctatttt agtagtttac ctatcaaagc gatggtacaa gctatcaaaa
     9601 aacagggact tccggcagtt gtatccaata gtgcaggaac ctttgtttgc aatcatttga
     9661 tgtaccaagc tctttattta gtggataaaa aattccctaa tatgagagca ggtttcatgc
     9721 atattccata tatgatggaa caagtagtaa ataagccgaa tactgcagga atgagtctat
     9781 gtgatattgt aagaggcata gaggtagcta ttgaagctat tgtagactac aaagataagg
     9841 atttgcagtt agtaggcggt gagactcact gataacctaa aaaggatagt caattatgct
     9901 tgtttactaa ctattaacta tgctaaatcg attgaggttg tttacataaa actctatatc
     9961 agagaagcct gatatagagt tttttcttgc tagttttagg attttcttgt aaaatagaaa
    10021 aagtgaagag aggtatgaaa tgagcaagaa agataaaaaa atcgaaattc aagtagcgga
    10081 tgccaaagtt aatgttggta aagacagttt tgaaggttat acattgacta tcggtaaaaa
    10141 agttatcgga gaaattgccg aattagacgg acaatttgcc attataaaga atgggaatgt
    10201 cgatagtttt tataaaaaat tggaaaaagc tgtggaaatt ttgattgaaa attataattt
    10261 agcaaaataa gtcttgtttt tttgaaattt tcatgatata atagtccatg ttgattgtag
    10321 gagagatagc gaagaggcta aacgcggcgg actgtaaatc cgctccttcg ggttcggggg
    10381 ttcgaatccc tctctctcca tttcattaat ggggtatagc caagcggtaa ggcaagggac
    10441 tttgactccc tcatgcgttg gttcgaatcc agctacccca gttcttaggt aataatcaag
    10501 ataaaaagca aaatatctta gggtatttta tttttataat tgaaagacgt gaatgatatg
    10561 aacatgtcct tgcgggtgct taggaaaaaa attataagta tgtcaagttt aagaaaaact
    10621 tgattgttgg aggatttttt agatgaatga atttgaagat ttgctaaata gcgttagtca
    10681 agttgagact ggtgatgttg ttagtgctga agtattgaca gttgatgcga ctcaagctaa
    10741 cgttgcaatc tctggaactg gtgttgaagg tgtcttgact cttcgcgaat tgacaaacga
    10801 tcgtgatgca gatatcaatg actttgttaa agtaggagaa gtattggatg ttcttgtact
    10861 tcgtcaagta gttggtaaag atactgatac agttacatac cttgtatcta aaaaacgcct
    10921 tgaagctcgc aaagcatggg acaaacttgt tggtcgcgaa gaagaagttg ttactgttaa
    10981 aggaacgcgt gccgttaaag gtggactttc agtagaattt gaaggtgttc gtggatttat
    11041 cccagcttca atgttggata ctcgtttcgt acgtaacgct gagcgttttg taggtcaaga
    11101 atttgatact aaaatcaaag aagttaacgc taaagaaaac cgcttcatcc tttcacgtcg
    11161 tgaagttgtt gaagcagcta ctgcagcagc tcgcgctgaa gtattcggta aattggctgt
    11221 tggtgatgtt gtaactggta aagttgctcg tatcacaagc ttcggcgctt tcgtcgatct
    11281 tggtggtgtt gacggattgg ttcacttgac tgaattgtca catgaacgta atgtatcacc
    11341 aaaatcagtt gtaactgttg gtgaagaaat tgaagtgaaa atccttgatc ttaacgaaga
    11401 agaaggacgt gtatcacttt cacttaaagc aacagtacca ggaccatggg atggcgttga
    11461 gcaaaaattg gctaaaggtg atgtagtaga aggaacagtt aaacgtttga ctgacttcgg
    11521 tgcatttgtt gaagtattgc caggtatcga tggacttgtt cacgtatcac aaatttcaca
    11581 caaacggatt gaaaacccaa aagaagctct taaagttggt caagaagttc aagttaaagt
    11641 tcttgaagtt aacgcagatg cagaacgcgt gtcactttct attaaagctc ttgaagaacg
    11701 tccagcccaa gaagaaggac aaaaagaaga aaaacgtgtt gctcgtccac gtcgtccaag
    11761 acgtcaagaa aagcgtgatt tcgaacttcc agaaacacaa acaggatttt caatggctga
    11821 tttgtttggt gatatcgaac tttaatcaaa ttgaaaattc acaaaatcct ttgtttacta
    11881 aacaaaggat ttttctggct ctttgtcaac tgtagtgggt tgaaaaaaag ctaagctcga
    11941 gaaaggacaa atttcgtcct ttcttttttg atattcagag cgatgaaaat ccgttttttg
    12001 aagttttcaa agttccgaaa accaaaggca ttgcgcttga taagtttgat gagattattg
    12061 gtcgcttcca gtttggcatt agaatagtgt agttgaaggg cgttgacaat cttttcttta
    12121 tctttgagga aggttttaaa gacagtctga aaaataggat gaacctgctt tagattgtcc
    12181 tcaatgagtc cgaaaaattt ctccggtttc ttattctgaa agtgaaacag caagagttga
    12241 tagagctgat agtggtgttt caagtcttct gaatagctca aaagcttgtc taaaatctgg
    12301 atattagggt ctttaatgtc tagtaatttt gtgataaaat gtaattgttc catatgaatc
    12361 tttctaatga gttgtttggt cgcttttcat tatagatctt atgggacttt ttttctacaa
    12421 taaaataggc tccataatat ctataggggg gttacccact acaaatatta tagagcccaa
    12481 aatcctttgt ttactaaaca agggattttt cttttgtctc tgctcctttt ttgatataat
    12541 agttctatgt taaaatcaga aaaacaatca cgttatcaaa tgttaaatga agaattgtcc
    12601 ttcctattgg aaggcgaaac caatgttttg gctaatcttt ccaacgccag tgctctcata
    12661 aaatcacgtt ttcctaatac cgtatttgca ggcttttatt tgttcgatgg aaaggaattg
    12721 gttttaggcc ccttccaagg aggtgtttcc tgcatccgta ttgcactagg caagggtgtt
    12781 tgtggtgagg cagctcactt tcaggaaact gttattgttg gagatgtgac gacctatctc
    12841 aactatattt cttgtgatag tctagctaaa agtgaaattg tggtgccgat gatgaagaat
    12901 ggtcagttac ttggagttct ggatctggat tcttcagaga ttgaggatta cgatgctatg
    12961 gatcgagatt atttggaaca atttgtcgct attttgcttg aaaagacaac atgggacttt
    13021 acgatgtttg aggaaaaatc ttaatgtatc aagcacttta tcgaaaatat agaagtcaaa
    13081 acttctccca gttagttggt caagaagttg tggctaagac tcttaaacaa gcggtggagc
    13141 aagagaaaat aagtcacgct tatctttttt ctggtcctcg tggaacggga aaaaccagtg
    13201 ttgctaaaat ctttgccaag gctatgaact gtcccaatca agtgggtggc gaaccttgca
    13261 ataactgcta tatttgtcaa gcagtgacgg acggtagttt agaagatgtc attgaaatgg
    13321 atgcagcttc taataatggg gtagatgaaa ttcgcgaaat tcgtgataaa tctacctatg
    13381 cgcctagcct tgctcgttat aaggtttata tcatagatga ggttcacatg ctgtctacag
    13441 gggcttttaa tgccctccta aagacgctgg aagaaccaac acagaatgta gtctttattt
    13501 tggccactac tgaattgcac aagattcctg ctactattct atcccgtgtg caacgttttg
    13561 agtttaaatc aattaagaca caggatatta aggaacatat tcactatatc ttagaaaaag
    13621 aaaatatcag ttctgaacca gaggctgtgg aaatcattgc cagacgggcg gaaggtggaa
    13681 tgcgggacgc cttgtctatt ttggatcaag ccctgagttt gacacaggga aatgagctga
    13741 cgactgctat ctctgaagaa attactggca ccattagcct atcagccttg gatgattatg
    13801 tggcggcctt gtctcaacag gatgttccca aagctttgtc ttgcttgaat cttctttttg
    13861 acaatggtaa gagcatgact cgttttgtga ccgatctttt gcactattta agagacttgt
    13921 taattgttca aacaggggga gaaaatactc atcatagttc agtctttgta gaaaatttgg
    13981 cacttcctca aaaaaatctg tttgaaatga ttcgcttagc aacagtgagt ttagcagata
    14041 ttaagtctag tttgcagccc aagatttatg ctgaaatgat gaccgtccgt ttggcggaaa
    14101 tcaagcccga accagctcta tcaggagcgg ttgaaaatga aattgctacg ctgagacagg
    14161 aagttgcccg tctcaaacaa gagctttcta atgtaggtgc ggttcctaaa caagttgcac
    14221 cagctcctag tcgaccagct acgggcaaaa cagtctatcg tgtcgatcgc aataaagtgc
    14281 aatctatctt acaagaggcc gtcgaaaatc ctgatttagc acgtcaaaat ctaattcgtt
    14341 tgcagaatgc ctggggagag gtaattgaaa gtctaggtgg gccggacaag gctctgctag
    14401 ttggttctca accggttgct gccaatgaac accatgctat tcttgctttt gagtctaact
    14461 tcaatgctgg tcaaactatg aaacgagaca atctcaatac catgtttggt aatatcctca
    14521 gtcaggcggc aggtttttca cctgagattt tagctatttc catggaggaa tggaaagaag
    14581 ttcgcgcagc cttttcagcc aaagccaaat cttctcaaac tgaaaaagaa gtagaagaaa
    14641 gcctgattcc agaaggattt gaatttttgg ctgataaagt gaaggtagag gaagactaaa
    14701 gaaagatttc atgatacaat aagtttatga ataaacaaca atttattatt atggcgctgt
    14761 ttacagctgc tgagacctat tttttcaatg aagcctggat gactggccgc tatattatgg
    14821 cagccttttg ggcaatttta ctctttagaa atttccgagt cagttatgtg atgggcaaaa
    14881 tcgttgatgt catcgatcag cattttaata ggaaagacta gccctcagct tccagacaaa
    14941 atcaaagcct tttaggcttt tttttgttat actagaaaag tatatttata gaatttttgc
    15001 tctatttctg gggaaatcag acgtttttct agtaagtact gtaaaagttt tgaaaaagaa
    15061 aggaactatc atgtcagtat tagagattaa agatcttcac gttgagattg aaggaaaaga
    15121 aattttaaaa ggggttaacc tgaccctgaa aacaggagaa attgccgcta tcatgggacc
    15181 aaatggtaca ggtaaatcga ctctttctgc cgctatcatg ggaaatccaa actatgaagt
    15241 aactaaaggt gaagttttgt ttgatggcgt aaacatcctt gagttggaag tggatgagcg
    15301 tgcgcgtatg ggacttttcc ttgctatgca atacccatca gaaatccctg gaattaccaa
    15361 tgctgagttt cttcgtgccg ctatgaatgc gggtaaagaa gatgatgaga agatttcagt
    15421 tcgtgagttt attactaagc tagatgaaaa aatggaattg ctcaacatga aagaagaaat
    15481 ggcagagcgt tacctcaacg aaggcttctc tggtggtgag aaaaaacgca atgaaattct
    15541 tcaacttttg atgttggagc caacatttgc tcttttggac gagattgact caggtcttga
    15601 tattgacgct cttaaagttg tgtctaaagg tgtcaatgcc atgcgtggtg aaggttttgg
    15661 tgctatgatc atcactcact accaacgtct tttgaactat atcacacctg atgtggtaca
    15721 cgtgatgatg gaaggtcgtg ttgtcctttc tggtggtcca gaattggctg cgcgtttgga
    15781 acgtgaagga tacgcaaaat tagctgaaga acttggctac gactacaagg aagaattgta
    15841 atttcctcgt atcttttagg agaagtaaat gactagagaa aatattaaac ttttttcaga
    15901 aatgcacgct gaaccaagct ggttggctga tctccgtcaa aaagcttttg acaagattga
    15961 gactttggaa ttaccagtta ttgagcgtgt caaattccac cgttggaatc tgggtgatgg
    16021 aacgattaca gaaaatgagc catcagcaaa tgttccagat ttcacagctt tagatcatca
    16081 cttgaagttg gtgcaagtag gaactcaaac tgttttcgaa caaactccag ttgagttagc
    16141 tgaacagggt gttgtcttca cagactttca ctcagcttta gaagaaattc cagagctgat
    16201 cgaagaattc ttcatgtcat ctgttaagta tgatgatgac aagttggcgg cttaccacac
    16261 agcttacttt aacagtggtg ctgtactcta tattccagat aacgtagaaa tcacagagcc
    16321 aattgaagga attttctacc aagatagcga tagcaatgtg ccgtttaaca agcatattat
    16381 gattatcgct ggtaaaaatt ctaagattag ttatctggag cgtttagagt cacgcggtga
    16441 aggaagtgac aaagtaactg ccaatatcac agtggaagtg attgcacgtt ctggtgcgca
    16501 agtcaagttt gctgctatcg accgtctagg tgaaaacgtc actgcctaca ttagccgtcg
    16561 tggtaaatta ggcaacgatg caagtattga ctgggctatc ggtgtcatga acgaaggaaa
    16621 tgtcgttgct gattttgata gtgacttgat tggtaatggt agccatgctg acctcaaggt
    16681 tgtagctctt tcaagtggtc gtcaggtaca agggattgat actcgtgtaa ctaactatgg
    16741 ctgcaactct atcggaaata tcctacaaca tggggttatc cttgaaaaag caactttgac
    16801 tttcaatggt atcggccaca tcatcaaggg tgctaaggga gcagatgcgc aacaagagag
    16861 ccgtgttctc atgctttcag accaagcgcg ttcagatgct aacccaattc ttttgattga
    16921 tgaaaatgat gtcactgcag gacacgcagc gtctatcgga caagttgatc cagaagacat
    16981 gtattacctc atgagtcgtg gattggataa ggcaactgca gagcgtttgg ttgttcgtgg
    17041 tttccttgga tctgttatcg tggagattcc agtcaaggaa gttcgtgatg aaatgattgc
    17101 aactatcgaa gagaaattgt caaaacgcta aggggaagcc tatgttagat gtagaagcga
    17161 ttcgcaagga ttttccaatt ttagatcaga ttgtcaatga tgaacctctg gtctatctgg
    17221 acaatgctgc gacgacacaa aaacccctag tagttctgaa agctattaac agttactatg
    17281 agcaggacaa tgccaatgtt caccgtggtg tccatacctt agcggaacga gcgacagctt
    17341 cttatgaagc tgctcgtgaa accattcgta agtttattaa tgcaggctct acaaaggaag
    17401 ttctctttac cagaggaacg acaaccagcc ttaactgggt ggcacgcttt gctgaggaaa
    17461 ttctcactga gggagaccag gtcttgattt cagtaatgga acaccattct aatatcattc
    17521 catggcagga agcttgtcga aagactggag cagagcttgt ctatgtctat cttaaagacg
    17581 gtgccttgga tatggaggat ttgcgagcta aattgactga taaggttaaa tttgtttccc
    17641 tagctcatgc ctccaatgtt cttggtgtga tcaatccgat caaggaaatc actcaattag
    17701 cccaccaagt tggggcaatc atggtagtgg atggtgctca atctacacct catatgaaga
    17761 ttgatgtcca ggacttggat ctggactttt tcgccttttc gggtcacaag atggctggtc
    17821 cgactggtat cggtgtcctt tacggcaaag aaaagtatct tgagcaaatg tctccagtag
    17881 aatttggcgg cgagatgatt gattttgtct acgagcaatt tgctagttgg aaggaattgc
    17941 cttggaaatt tgaggctgga acgccaaata tggcaggagc tattggactt gcgactgcag
    18001 ttgattattt ggaaaagatt ggtatggatg ccgttgaagc tcatgaacag gaattgattg
    18061 cgtacgtcta tccaaaactg caggcaattg agggattgac catttacggt tctcaggatt
    18121 tggctcaacg ttcgggtgtt attgccttta acctaggtga tctccatcct cacgatcttg
    18181 cgacggctct ggattatgaa ggagtggctg ttcgtgctgg tcaccattgt gcgcaaccct
    18241 tgcttcagta tttggaagtc ccagcaacag ctcgtgcaag tttttatatc tacaatacca
    18301 aggcagattg cgacaaacta gtcgatgccc tacaaaagac aaaggagttt ttcaatggca
    18361 ctttctaaac tagatagcct ttatatggca gtggtagcag accattcgaa aaatccacat
    18421 caccaaggga agttagaaga tgctgagcaa atcagtctca acaatccgac ttgtggggat
    18481 gtcatcaacc tctctgtcaa gtttgatgca gaggaccgtt tggaagatat tgcttttcta
    18541 aattcaggat gcacgatttc aactgcttct gctagtatga tgacagatgc cgttttagga
    18601 aaaaccaaac aagaaatttt agaactggcg actatttttt ctgaaatggt tcaagggcaa
    18661 aaagatgagc gtcaaggcca acttggagac gcggcattct tgtcaggtgt tgccaaattc
    18721 cctcaaagaa tcaagtgtgc aaccctagct tggaatgccc ttaagaaaac aattgaaaat
    18781 caagaaaaac agtaagacaa gtttcttttg tcttatgaat tattagaaat gaagaaagaa
    18841 aggatactat ggctgaagaa agagtagaac caaaaccaat tgaccttggt gaatataaat
    18901 ttggtttcca tgacgatgta gagcctgtct tatcgacagg aaaaggactc aacgaaggtg
    18961 ttattcgtga attatctgct gctaagggtg agcctgagtg gatgttggag ttccgtttga
    19021 agtcttatga aaccttcaaa aaaatgccca tgcaaacttg gggagcagac ttgtcagaga
    19081 ttgactttga tgacttaatc tactaccaaa aaccatctga caaaccagcc cgttcttggg
    19141 atgatgtacc tgaaaagatt aaagaaacct ttgaacgtat cgggattcca gaagctgaac
    19201 gtgcttattt agcaggggct tctgcccagt acgagtcaga agtggtttac cgcaacatga
    19261 aggaagagtt ccaaaaatta ggtattatct ttacagatac agattccgca ctcaaggaat
    19321 acccagactt atttaaacaa tactttgcga agttggtacc gccgacagat aacaagttgg
    19381 cagccctcaa ctcagcagta tggtcgggtg gaacttttat ctacgtgcca aaaggtgtca
    19441 aggtagatat tccacttcaa acttatttcc gtatcaataa cgaaaatata ggtcagttcg
    19501 aacgtacctt gattatcgtt gatgagggag caagcgtcca ctacgtagaa ggatgtacag
    19561 caccaacata ttcaagcaat agcttacacg ctgccattgt agaaattttt gctttggacg
    19621 gagcttatat gcgttataca actatccaaa actggtctga taacgtctat aacttggtaa
    19681 caaagcgtgc taaggctcaa aaggatgcca ctgttgagtg gattgatgga aacttgggtg
    19741 ccaaaacgac tatgaaatat ccatctgttt accttgatgg agaaggagcg cgtggtacca
    19801 tgctctctat cgcctttgct aatgcagggc aacaccaaga cacgggtgct aagatgattc
    19861 acaatgctcc acataccagc tcgtctattg tgtctaaatc catcgctaaa ggtggaggaa
    19921 aggttgacta ccgtggacaa gtcaccttta acaagaactc taagaaatct gtttcccaca
    19981 ttgaatgtga taccattatc atggatgact tgtcagcatc agatactatt ccatttaatg
    20041 aaattcacaa ctcgcaagtg gctttggaac acgaagccaa agtatctaag atttcagaag
    20101 agcaattgta ttatctcatg agccgtggat tgtcagaatc tgaggcaact gaaatgattg
    20161 tcatgggatt tgtagaaccc tttacaaaag aacttccaat ggaatacgca gttgagctga
    20221 accgcttgat tagctatgaa atggagggat cagttggata aaatttgatt ttatactctt
    20281 cgaaaatctc ttcaaaccac gtcagcatcg ccttaccgta tgtatggtta ctgacttcgt
    20341 cagtttcatc tacaacctca aaacagtgtt ttgagcaagc tgcggctagc ttcctagttt
    20401 gttctttgat tttgagtatt agatttactc aaaatcaagg attttgaaga tgaacttgta
    20461 tcaaaaaatc gcggtttaaa atcgcgattt tttataattt ctcgttaaca aagcggacaa
    20521 actgattcca ccaaactttt aagaagaagg ctttttcaat tttcttgtct gctaccattt
    20581 cgaaactagg gcgctctgtg gtgatgtaac cttgaccaat caagtccttg tcttcataag
    20641 tcaaatggcc aaccactgtt ccagcttcaa gtggtgctgg gattgctttg gaatcaggtg
    20701 tgaattgaac agattgggaa gattgattcc caacacgttc gattagatag atatcctctg
    20761 gagccactgc agttactgta tcttcttttc catcttgtac aggggttttg ctatcttgat
    20821 aggcatcgcc ttgttgaacg attttgcgaa gtgtaaatgt agaagaaata taatccatta
    20881 gggaagatgt agctgtaaat cgagcgtaag gattattgtc ttgatgatct gcatttaaaa
    20941 caactgtgat gactctcatg cctttttcga cagtagtacc aacaaaagac tctccagcct
    21001 tatctgttgt tcctgttttt agcccatcaa aaccaccacg gtaagcaggc ataccttcta
    21061 acatgtagtt ggttgaagtg attgtcatcc cagcaaaagt agaagaaggt tttttggtga
    21121 tttctaagac ttgtgggtat tttttgatga ggttgcgagc aacgatagcg acatcataag
    21181 cactaagctt attttcctca tcttttttag aacctgggta aatgttatcc cctagagttt
    21241 cattgttaag acctgtcgta ttgacaacag tggcatcctg aattccccat tccaagagtt
    21301 ttgcccgcat catatcgacg aaatcttttt ctgagccagc aattttctca gctagggcaa
    21361 tagcggcgct gttggcacta gataccagag ttgcttcaag caactcttcg acagtataat
    21421 tacgggcctc cataggaata ttactggctt cagaatttgt cgtcaattga taaggataat
    21481 cagaaatatc tacaggagtg gagagggtaa tacttccgtt ttccaaagct tcatagacca
    21541 gataaacagt aatcaatttt gttatggaag caatttcgac aggttgcgtt gcatccttct
    21601 catagagaat tttaccagta tttgcctcaa cagcaatcgc atgtttagcg gcaatggtaa
    21661 aatcttgagc aacagcagta gaagcacccc ctaaaagaga gacagttaac aaagttaaaa
    21721 atattttttt catagtagtc ttattctatc ataaagaaaa aaaatattct tgctttaata
    21781 attcatctgt taagcttttt gaaaatatgg taaaataaag tgagggaggt aactcatgtt
    21841 tcgtagaaat aaattatttt tttggaccac agaaatttta ctcttaacca tcatctttta
    21901 cctatggaga cagatgggat ctttgattaa cccttttgtt agcgtgctta atacaattat
    21961 gattccattt ttattagggg gctttcttta ttatttgaca aaccctattg ttactttctt
    22021 aaataaagtc tgtaaactca atcgtttgct tggtatttta attaccttgt gtactttggt
    22081 ctggggaatg gtcataggtg ttgtctatct cttacctatt ttgattaatc agttatctag
    22141 tttgattata tctagtcaaa ctatttatag tcgagtacaa gacttaatca tagacttatc
    22201 taattatcct gcgctccaga atttggatgt agaagctaca attcagcagt taaacttatc
    22261 ctatgttgat attcttcaaa atatcctaaa tagcgtatca aatagtgtgg ggagcgtctt
    22321 gtcagctctt atcagtactg ttttgatttt gattatgact ccagtttttt tggtttattt
    22381 cttattagat ggacataaat tcttgcccat gcttgaaaga acgattctaa agagggatcg
    22441 cttgcatatt gcaggcttat taaagaattt aaatgcgacg attgctcgct atattagtgg
    22501 agtttcgatt gacgcaatca ttataggttg tttggcttat attggctata gtattattgg
    22561 tttaaaatat gctttagttt ttgccatttt ttctggtgta gccaatttaa ttccttatgt
    22621 ggggccaagt attggtttga ttcctatgat catcgcaaat atattcactg atccccatag
    22681 actgctgatt gcagtgattt atatgcttgt tgttcagcag gtagatggca atatcttata
    22741 tcctcgaatc gtaggaagtg ttatgaaggt tcatccaatc acgattttag ttttactttt
    22801 gttgtcaagc aatatctatg gtgtagttgg aatgattgtc gcagtgccaa cctattctat
    22861 cttgaaagaa atttctaagt tcttatcccg tttgtatgaa aatcataaaa taatgaaaga
    22921 acgagaaaga gaattagcta agtaaaagtc aggagaaccc tgatttttct ttactggaag
    22981 tggcctttag attagaagac tgaaaataag ttaaagtctt aaactaattt tcacagctaa
    23041 gaatagtaga agttaatctg ataaaaatcg aaaaaaccag tggaattctg tgtcagggta
    23101 agttccactg gttttcatag tctattaaag ttcgaatgaa acctatttat agtagattga
    23161 aactagaata gtacacctct aattctaaaa cattgttaga aatcgatttg actgtcctga
    23221 tctattcgtc ctattcttat ttcattttac tatattttgg tgcaataagt gaaaagtaga
    23281 ccgaataata taaggattga ttttatagtt tttaaactca aatgaattga aataaagaga
    23341 gtacgaaaat tctcatctga aagtatttta gaataattct cttcgtgaat ttcttcaaaa
    23401 cagatagctt catcttaggt atgtgatttc tttttgcatt tttgagttag ataaggtata
    23461 atggttttat tgtcttttgg ggtcgttacg gattcgacag gcattatgag gcatattttg
    23521 cgactcgtgt ggcgacgtaa acgctcagtt aaatataact gcaaaaaata acacttctta
    23581 cgctctagct gcctaaaaac cagcaggcgt gacccgattt ggattgctcg tgttcaatga
    23641 caggtcttat tattagcgag atacgattaa gccttgtcta gcggtttgat aagagattga
    23701 tagactcgca gtttctagac ttgagttatg tgtcgagggg ctgttaaaat aatacataac
    23761 ctatggttgt agacaaatat gttggcaggt gtttggacgt gggttcgact cccaccggct
    23821 ccattattcc tttgcattcc ttggtaaaac gttgttaaat caacgttttt tatttttatc
    23881 tttggtattc ctttgcattc ttttgctaaa aagggagtca caaacagacc ctattttaaa
    23941 aaaaggatag aaaaaaggat acaacatttg tcgcatccta aaaataatct tttttcgacg
    24001 gaagacatgg gattcgaacc cacgcacgct attacacgcc taccgcgttt ccaacacggc
    24061 ctcttaagcc tcttgagtaa tcttccaata cttactcaaa tagtctacca taaaggctct
    24121 tatcttgcaa taaaaattct agaaataaga aaaaatgata gattttgaaa gaaaatgata
    24181 aaaaatgctt gacttcgaaa gaaagtatga tagaatgaat agtgtaaacg ataacaggag
    24241 gtgattcagt gttaaaaaca gaacgtaaac aactaatttt agaggagtta aatcagcatc
    24301 atgtagtttc tctagaaaaa ttagttagtt tgctagaaac gtcagaatca acggttcgaa
    24361 gagacttgga tgagttggaa gcggaaaaca agcttcgtcg tgtgcatggt ggagcagaac
    24421 tcccccactc cttacaggaa gaagaaacca ttcaagaaaa atctgtcaaa aaccttcaag
    24481 aaaagaagtt gctggctcag aaagcagcct ctctcattaa agaaaaagat gtcatcttta
    24541 tcgatgctgg aacaacaact gcttttttga ttcatgaatt ggtcaataag aatgttacag
    24601 ttgtgaccaa ctccattcac catgccgctc agttggttga aaagcagatt ccaactgtca
    24661 tggttggagg aaacgtcaag acggcgacag atgctagtat cgggggcgtt gctcttaacc
    24721 agattaacca attgcacttt gaccgtgcct ttatcggaat gaatggtgtt gacgatggct
    24781 attatacgac tcctgatatg gaggagggag ctgtgaaaag agctattttg gagaatgcca
    24841 agcagaccta cgtcttggtg gattcgtcaa aaattggaca aacttgcttt gccaaggtag
    24901 caccactcaa acgcgctatc gttatcacta gtcaagggca tgagctcttg caggttatta
    24961 aggagaaaac ggaggtaata gaagtatgat ttatacagtc acactcaatc catccattga
    25021 ctatatcgtt cgtttggacc aagtcaaagt tggtagtgtc aatcgtatgg acagtgatga
    25081 taagtttgct ggtgggaaag gaatcaatgt cagccgtgtc ttgaaacgtt tgaatatacc
    25141 aaatacagcg acgggattta tcggtggctt tactggtaaa tttatcacag atactctagc
    25201 agaggaagaa atcgagacac gttttgtcca agtggcagaa gatactcgta tcaatgttaa
    25261 aatcaaagca gaccaagaaa cagaaatcaa cggaacgggt ccaactgttg aaccggttca
    25321 gctagaagaa ttgaaagcta ttttatctag tctgacagta gaagatacag ttgtctttgc
    25381 aggttcaagt gctaaaaatc taggcaatgt tatctataag gatttgattt ccttgacgcg
    25441 ccagactggt gcgcaagtgg tctgtgactt tgaaggacag accttaattg atagtttgga
    25501 ctaccagcct cttcttgtaa aaccaaacaa tcatgaactt ggagcgattt ttggggttaa
    25561 actcgaaagt ttagatgaaa ttgagaaata cgctcgtgag ttactggcta agggtgctca
    25621 aaatgttatt atctctatgg ctggtgatgg cgcccttctt gtcacatctg agggagctta
    25681 cttcgctaaa ccaatcaaag gaacagtcaa aaattcagtt ggagctggtg attctatggt
    25741 tgctggattc acaggtgaat ttgtcaaatc aaaagacgca gtagaagcct tcaaatgggg
    25801 agtggcttgc ggaacggcaa ctaccttctc agatgacttg gcaacggcgg aatttattaa
    25861 agaaacatat ggaaaagttg aggtagaaaa aagatgaaaa ttcaagacct attgagaaaa
    25921 gatgtcatgt tgctagattt gcaggcaact gaaaaaacag ctgtcatcga cgagatgatt
    25981 aaaaatttga cagagcacgg ttatgtaaca gattttgaaa catttaaaga aggaattttg
    26041 gcgcgtgaag ctttgacttc tactggtttg ggtgatggaa tcgcaatgcc tcacagcaaa
    26101 aacgctgctg tcaaagaagc gacagttcta tttgctaagt caaacaaggg tgttgactac
    26161 gagagcttgg atggacaagc aactgacctc ttcttcatga ttgcagctcc agaaggtgcc
    26221 aatgatactc acttggcagc cttggcagaa ttgtctcaat acttgatgaa agacggtttt
    26281 gcagacaaac ttcgtcaagc aacatctgca ggccaagtta tcgaactttt tgaccaagct
    26341 tcagaaaaaa ctgaggaact tgttcaagca cctgctaatg actctggtga ctttatcgta
    26401 gctgttacag cttgtacaac aggtattgcc cacacttaca tggcccaaga agcccttcaa
    26461 aaagtagctg ctgaaatggg ggttggtatc aaggtcgaaa ccaacggtgc tagcggtgtt
    26521 ggaaatcaac taactgcaga agatatccgt aaggctaaag ctattatcat tgcagcagac
    26581 aaggccgttg aaatggatcg atttgatgga aaaccattga tcaatcgtcc agttgctgac
    26641 ggtatccgta agacagaaga gctaattaac ttggctcttt caggagatac tgaagtctac
    26701 cgtgccgcta atggtgccaa agctgcaaca gcctctaacg aaaaacaaag ccttggtggt
    26761 gccttgtaca aacacttgat gagtggtgta tctcaaatgt taccattcgt tatcggtggt
    26821 ggtatcatga ttgcccttgc cttcttgatt gacggtgctt tgggtgttcc aaatgaaaac
    26881 cttggcaatc ttggttctta ccatgagtta gcttctatgt ttatgaaaat tggtggagct
    26941 gcctttggtt tgatgcttcc agtctttgcg ggttatgttg cctactctat tgctgaaaaa
    27001 ccgggtttgg tagcaggttt cgtggctggt gctattgcca aagaaggttt tgcctttggt
    27061 aaaattcctt atgccgcagg tggtgaagca acttcaactc ttgcaggtgt ctcatctggt
    27121 ttcctaggtg cccttgttgg tggatttatc gcaggtgcct tggttcttgc catcaagaaa
    27181 tacgttaaag ttcctcgttc actcgaaggt gctaaatcaa tccttctatt gccacttctt
    27241 ggaacaatct tgacaggatt tgttatgcta gctgtgaata tcccaatggc tgcaatcaac
    27301 actgctatga atgacttcct aggcggtctt ggaggaggtt cagctgtcct tcttggtatc
    27361 gtccttggtg gaatgatggc tgttgacatg ggtggaccag ttaataaagc agcttatgtc
    27421 tttggtacag gtacgcttgc agcaactgtt tcttcaggtg gttctgtagc catggcagca
    27481 gttatggctg gaggaatggt gccaccactt gcaatctttg tcgcaactct tcttttcaaa
    27541 gataaattta ctaaggaaga acgtaactct ggtttgacaa acatcatcat gggcttgtca
    27601 tttatcactg agggagcgat tccatttggt gccgctgacc cagctcgtgc gattccaagc
    27661 ttcatccttg gttcagcagt agcaggtgga ctcgttggtc ttactggtat caaactcatg
    27721 gcgccacacg gaggaatctt cgttatcgcc cttacttcaa atgctctcct ttacctcgtt
    27781 tctgtcttgg taggagcaat cgtaagtggt gtggtttatg gttacctacg caaaccacaa
    27841 gcataaaaaa tagaaaaatg aaaagattgg accgtttggt gcagtctttt tctcttcccg
    27901 aaatgcctgt gaaatatggt ataatagaag aatggcaaac aagaatacaa gtacaacaag
    27961 acggagaccg tctaaagcag aactggaaag aaaagaagcg attcaacgaa tgttgatttc
    28021 gttaggaatt gcgattttat tgattttcgc agccttcaaa ttaggggctg caggtataac
    28081 cctttataat ttaattcgct tgctagtggg tagcctagct tatctggcga tattcggcct
    28141 attaatctat ctcttctttt tcaagtggat acgaaaacag gaaggactct tatctggctt
    28201 tttcaccata tttgctggct tactcttgat ttttgaggcc tacttggttt ggaaatatgg
    28261 tttggacaag tccgttctaa aagggaccat ggctcaggtt gtgacagatc tgactggttt
    28321 tcgaacgact agctttgctg gagggggctt gatcggggtc gctctttata ttccaacagc
    28381 ctttctcttt tcaaatatcg gaacttactt tattggttct atcttgattt tagtgggttc
    28441 tctcctagtc agcccttggt ctgtttacga tattgctgaa tttttcagta gaggctttgc
    28501 caaatggtgg gaagggcacg agcgtcgaaa agaggaacgc tttgtcaaac aagaagaaaa
    28561 agctcgccaa aaggctgaga aagaggctag attagaacaa gaagagactg aaaaaacctt
    28621 actcgatttg cctcctgttg atatggaaac gggtgaaatt ctgacagagg aagctgttca
    28681 aaatcttcca cctattccag aagaaaagtg ggtggaacca gaaatcatcc tgcctcaagc
    28741 tgaacttaaa ttccctgaac aggaagatga ctcagatgac gaagatgttc aggtcgattt
    28801 ttcagccaaa gaagcccttg aatacaaact tccaagctta caactctttg caccagataa
    28861 accaaaagat caatctaaag agaagaaaat tgtcagagaa aatatcaaaa tcttagaagc
    28921 aacctttgct agctttggta ttaaggtaac agttgaacgg gccgaaattg ggccatcagt
    28981 gaccaagtat gaagtcaagc cggctgttgg tgtaagggtc aaccgcattt ccaatctatc
    29041 agatgacctc gctctagcct tggctgccaa agatgtccgg attgaagcac caatccctgg
    29101 gaaatcccta atcggaattg aagtgcccaa ctccgatatt gccactgtat ctttccgaga
    29161 actatgggaa caatcgcaaa cgaaagcaga aaatttcttg gaaattcctt tagggaaggc
    29221 tgttaatgga accgcaagag cttttgacct ttctaaaatg ccccacttgc tagttgcagg
    29281 ttcaacgggt tcagggaagt cagtagcagt taacggcatt attgctagca ttctcatgaa
    29341 ggcgagacca gatcaagtta aatttatgat ggtcgatccc aagatggttg agttatctgt
    29401 ttacaatgat attccccacc tcttgattcc agtcgtgacc aatccacgta aagccagcaa
    29461 ggctctgcaa aaggttgtgg atgaaatgga aaaccgttat gaactctttg ccaaggtggg
    29521 agttcggaat attgcaggtt ttaatgccaa ggtagaagag ttcaattccc agtctgagta
    29581 caagcaaatt ccgctaccat tcattgtcgt gattgtggat gagttggctg acctcatgat
    29641 ggtggccagc aaggaagtgg aagatgctat catccgtctt gggcagaagg cgcgtgctgc
    29701 aggtatccac atgattcttg caactcagcg tccatctgtt gatgtcatct ctggtttgat
    29761 taaggccaat gttccatctc gtgtagcatt tgcggtttca tcaggaacag actcccgtac
    29821 gattttggat gaaaatggag cagaaaaact tcttggtcga ggagacatgc tctttaaacc
    29881 gattgatgaa aatcatccag ttcgtctcca aggctccttt atctcggatg acgatgttga
    29941 gcgcattgtg aacttcatca aggctcaggc agatgcagac tacgatgaga gttttgatcc
    30001 aggtgaggtt tctgaaaatg aaggagaatt ttcggatgga gatgctggtg gtgatccgct
    30061 ttttgaagaa gctaagtctt tggttatcga aacacagaaa gccagtgcgt ctatgattca
    30121 gcgtcgttta tcagttggat ttaaccgtgc gacccgtctc atggaagaac tggagatagc
    30181 aggtgtcatc ggtccagctg aaggtaccaa acctcgaaaa gtgttacaac aataaaaaaa
    30241 tagcttcttt ccgagtttgg agggaagcta ttttagtggc tattgattgc ttttattttc
    30301 tgaagttggc gcattggact gtttttcgtt ttcagtagca ggtttacttg aagcaggagt
    30361 agaagagtcc tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt
    30421 tggtgtttcc tcttgctgtg ttttttcttg actagtgtta gtctctttag ttggactggt
    30481 gttttcctta ggggattcct tttggatttc tttgacaatg gttgtcgtct ggcttgtcgt
    30541 aggttctttt ttaatatttt tgttattatc caaggcgttc atgatcgtga tacccgcggt
    30601 aatcaagcca aggatactag cgattgtagc aacggttttt tgaaagactg taaagccttt
    30661 tttgatgtgt tctgtttttg gttttgaagt tctacgatag ttagacatac attctctcct
    30721 ttgattatga tttattatac tctgtttctt taaaaaaatc ttaaaaaaag agaaattgcc
    30781 ctttcttgtc gcaggctccg tttcatgata caatagaagg agtgatttta gaaagcgtga
    30841 gaaacatgat ttactttgat aattcggcga cgaccaggcc ctatccagaa gcccttgaaa
    30901 cctatatgca ggtggcttca aaaattttag gaaatccatc tagtctccat cgtttgggag
    30961 accaggcaac acgaatttta gatgcttccc gtcaacagat tgcagattta atcggtaaga
    31021 aaagtgatga aatcttcttt acatctggtg ggacagaagg ggataactgg atcatcaagg
    31081 gagtagcatt tgaaaaagcc cagtttggca agcacatcat cgtatcagcc attgaacatc
    31141 cagcagttaa ggaatcagcc ctctggttga aagctcaagg ttttgaagtg gattttgctc
    31201 cagttgataa caaaggattt gtggatgttg aggcgctaga agatttgata agacctgata
    31261 cgaccctcgt ttccatcatg gcagttaaca atgaaattgg ctctgttcag cccattgagg
    31321 ctatttcaaa actattggca gacaagccaa ctatttcctt ccacgttgat gcggttcagg
    31381 cgcttgccaa gattccgact gaaaagtatc tgacagaacg agtggatttc gcgactttct
    31441 ctggtcacaa gttccacgga atccgtggtg ttggttttat ctatatcaag tctggcaaga
    31501 agattacgcc tcttttaaca ggtggtggtc aggaacgtga ttaccgttcg acaactgaaa
    31561 atgtggcagg aattgcagcg accgctaagg ctctccgttt atctatggaa aagctagata
    31621 tctttaggag caagactggg cagatgaagg cagtgattcg tcaagcactt ctggactatc
    31681 cggatatatt tgtcttttca gatgaggaag acttcgcccc tcatattctg acttttggaa
    31741 tcaagggtgt tcgtggtgag gtcattgttc acgcctttga agactatgat attttcatct
    31801 caacgacctc ggcttgttcg tccaaggctg ggaaaccagc cggaaccctg attgctatgg
    31861 gagtggacaa ggataaggct cagtcagctg tgcgtcttag tctagacctt gaaaatgata
    31921 tgagtcaggt cgagcagttc ttgaccaagc taaaattaat ttacaatcaa actagaaaag
    31981 taagatagga gcattcatgc agtattcaga aattatgatt cgctacggtg agctgtcaac
    32041 caagggcaaa aatcgtatgc gtttcatcaa taaacttcgc aataatattt cagacgtttt
    32101 gtctatctat ccccaagtta aggtaacagc agatcgcgac cgtgcccacg cttacctcaa
    32161 tggagcagat tacacagcag tagcagaatc actcaaacaa gtatttggaa ttcaaaactt
    32221 ttcccctgtt tataaggttg aaaaatctgt agaagttctg aagtctgctg tccaagagat
    32281 tatgcaggac atctacaagg aaggcatgac ctttaaaatc tctagcaagc gtagcgacca
    32341 cacctttgaa ttggacagtc gtgaactcaa ccaaacgctt ggaagggctg tattcgaagc
    32401 cattccaaac gtacaagctc aaatgaaaag tcctgacatc aatcttcagg tggagatacg
    32461 tgaagaagca gcctatcttt cttatgaaac cgttcgaggg gcaggtggat taccagtggg
    32521 aacttctggt aagggcatgc tcatgttgtc agggggaatc gattcccctg tagctggcta
    32581 tctagcgctt aaacgagggg tagatataga ggcagttcac tttgccagcc caccttacac
    32641 gagtcctggt gctcttaaaa aagcccaaga tttgacccgt aaattaacca aatttggggg
    32701 aaatatccag tttatcgaag ttccttttac agagattcaa gaggaaatca aagccaaagc
    32761 gccagaagcc taccttatga ccttgacgcg tcgttttatg atgcgtatta ctgaccgtat
    32821 tcgtgaggta cgaaatggtt tagttatcat caatggggaa agtctaggtc aagtagccag
    32881 ccaaaccctt gaaagtatga aggctatcaa tgctgttacc aacactccca tcattcgtcc
    32941 tgtggttacc atggacaagt tggaaatcat tgacatcgcc caggaaatcg atacctttga
    33001 catttcaatc caaccgtttg aagactgttg taccattttt gcaccagatc gtccaaaaac
    33061 aaatcctaaa attaagaatg cggagcagta cgaagcgcgt atggatgttg aaggcttggt
    33121 tgagcgagca gtggctggaa tcatgattac tgaaatcaca cctcaagccg aaaaagatga
    33181 agttgatgac ttgattgaca atctgctcta attcagaaaa tccaaaagaa tagcgaaaat
    33241 cagtaaaaaa agttagtttt ttctctaaaa acaggtaaaa aactaacttt ttttattttt
    33301 atgatataat gatataaaat tttgaatata gagagttttc tggcaatgaa tcaatcctac
    33361 ttttatctaa aaatgaaaga acacaaactc aaggttcctt atacaggtaa ggagcgccgt
    33421 gtacgtattc ttcttcctaa agattatgag aaagatacag accgttccta tcctgttgta
    33481 tactttcatg acgggcaaaa tgtttttaat agcaaagagt ctttcattgg acattcatgg
    33541 aagattatcc cagctatcaa acgaaatccg gatatcagtc gcatgattgt cgttgctatt
    33601 gacaatgatg gtatggggcg gatgaatgag tatgcggctt ggaagttcca agaatctcct
    33661 atcccagagc agcagtttgg tggtaagggt gtggagtatg ctgagtttgt catggaggtg
    33721 gtcaagcctt ttatcgatga gacctatcgt acaaaagcag actgccagca tacggctatg
    33781 attggttcct cactaggagg caatataccc agtttatcgg tttggaatac caagaccaaa
    33841 ttggttgctt gggcgttttt tcatctgcaa actggctcca ccaagaagcc tttaaccgct
    33901 atatcgagtg ccagaaacta tcgcctgacc agcgcatctt catctatgta ggaacagaag
    33961 aagcagatga tacagacaag accttgatgg atggcaatat caaacaagcc tatatcgact
    34021 cgtcgctttg ctattaccat gatttgatag cagggggagt acatctggat aatcttgtgc
    34081 taaaagttca gtctggtgcc atccatagtg aaatcccttg gtcagaaaat ctaccagatt
    34141 gtctgagatt ttttgcagaa aaatggtaag ttaagaaagg aaaaaacgaa atgcatattg
    34201 aacatcttag ccactggagt ggtcatctta accgtgaaat gtaccttaac cgttatggac
    34261 atggtgggat tccagttgtg gtctttgctt catcaggtgg tagtcacaac gaatactatg
    34321 attttggcat gattgatgcc tgtgcttcct ttatcgagga aggccttgtc cagttcttta
    34381 ccctatctag tttggatagt gagagctggt tggttacttg gaaaaatgct catgaccaag
    34441 cggaaatgca ccgtgcctac gaatgttatg tgattgagga ggccattctt ttatcaagca
    34501 caagacaggt tggtttgatg gcatgatgac gacaggttgc tctatgggag cctatcatgc
    34561 actcaatttc ttcctccagc atccagatgt ctttaccaaa gtgattgctc tcagtggtgt
    34621 ttacgacgca cgtttctttg tcggtgatta ctacaacgat gatgctattt accaaaactc
    34681 gccagtagat tatatttgga accaaaacga cggctggttt attgaccgtt accgtcaggc
    34741 agagattgtg ctgtgtacgg ggcttggagc ctgggaacaa gatggtttgc catcctttta
    34801 caagctcaaa gaagcctttg acaagaaaca aattccagcc tggtttgctg aatggggaca
    34861 tgatgtcgcc catgactggg aatggtggcg taaacaaatg ccttatttcc tcggtaatct
    34921 ctatttataa aaggagttac ctatgaatta ccttgttatt tctccctact atccacaaaa
    34981 ctttcaacag tttaccatcg aactagctaa taaaggcatc acagtcttgg gaattggtca
    35041 agagtcttac gagcaattgg atgagccctt gcgcaatagc ttgaccgagt attttcgtgt
    35101 tgataatctt gagaacatag atgaagtcaa acgtgcagtt gcttttctct tttataaaca
    35161 tggtccaatt gaccgcatcg agtctcacaa tgaatactgg cttgagctag acgcaacact
    35221 cagagaacaa ttcaatgttt ttggtgccaa accagaggat ctcaaaaaga cgaaatataa
    35281 gtctgaaatg aagaaacttt tcaaaaaagc aggtgttcct gtggtacctg gagctgttat
    35341 caagacggaa gcagatgttg atcaagcagt gaaagaaatc ggtcttccaa tgattgccaa
    35401 acctgataat ggagtgggag cagccacaac ctttaaactt gagacagaag acgatatcaa
    35461 tcacttcaag caagaatggg accattcaac cctttatttc tttgaaaaat ttgtcacttc
    35521 cagcgaaatc tgtacctttg acgggctcgt ggacaaggat ggaaagattg tcttctcaac
    35581 aacctttgac tacgcctata caccgcttga cctcatgatt tataagatgg acaattctta
    35641 ttatgtgctc aaggatatgg atcctaaact gcgcaagtat ggggaagcaa ttgtcaaaga
    35701 atttggtatg aaagaacggt ttttccatat tgagttcttc cgtgaggggg acgattatat
    35761 taccatcgag tacaataacc gccctgcagg tggttttacc attgatgttt ataactttgc
    35821 tcattccttg gacctctatc gtggctatgc agctattgtc gcaggagagg agttcccggc
    35881 gtcagacttt gaaactcagt attgtttggc tacttctcgc cgtgcaaatg ctcactatgt
    35941 ttattcagaa gaggatttgc ttgccaaata tagccagcag ttcaaagtta aaaaagtcat
    36001 gccagctgcc ttcgcggaac ttcaaggaga ttacctgtat atgctgacca ctccgagtcg
    36061 acaagaaatg gagcagatga ttgcagattt cggacaacgt caagaataag aactatcgga
    36121 ttaaggaaat taactccctt aatccttttg ttttgtctga taaaaaataa gagcatccca
    36181 acaaggtagc tatcataaaa cttgttcgat aactatttga agcaggatta ggtggtcaga
    36241 aattgaattt taatatttca attgagtcat agtattgtgt ttgcgtatcc ttaaatcagc
    36301 taaaaggatc catgacgaca cctatacgat atagttttca agataccaaa caagtctatt
    36361 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggtttc tcaaaacact
    36421 gttttgaggt tgtggataga actgacagag tcagtatcat atacctacgg caaggtgaag
    36481 ctgacgtggt ttgaagagat tttcgaagag tataaaatat tcaggtgacg catagatata
    36541 gttaattgaa gctttgtttg aaatctgata aaataatgat attactaagt tttaaaaact
    36601 aaagaaaagg gaagatatga ttacaggcga attaaaaaat aaaatcgatc agctgtggga
    36661 aattctttgg acagaaggaa acgcaaatcc tttaacaaat attgaacagt tgacttatct
    36721 cttatttatg aaagatttgg atagtgtcga gcttggacgt gaaagtgatg ctgaatttct
    36781 agggattcct tatgagggag tttttccaaa agataaacct gaataccgtt ggtcaacttt
    36841 taaaaatata ggagatgctc aggaagttta tcgtttaatg actcaggaga tttttccgtt
    36901 tattaaaaat ctcaaggggg atacagatga tacagccttt tcacgatata tgcgagaagc
    36961 tatttttcaa ataaataaac ctgctacgct tcaaaaggca atttctatct tagatgtttt
    37021 tccaactagg ggattagatg tagattttga taatgacaaa caaagtatta ctgatatcgg
    37081 agatatctat gaatatctgt tatcaaaatt gtcgaccgca ggtaaaaatg gacagttccg
    37141 tacacctcgt cacatcatcg atatgatggt tgagttgatg caaccgacta tcaaagatat
    37201 catctcagat cccgctatgg gttctgctgg cttcttagta tctgctagcc gttacttaaa
    37261 gcgtaagaaa gatgaatggg aaaccaatac agataatatc aatcattttc ataatcagat
    37321 gtttcatgga aatgatacgg atacgactat gttgagactt ggggcgatga acatgatgct
    37381 acatggagta gaaaatccac aaatcagtta ccttgactcg ctgtctcaag ataatgaaga
    37441 agccgataaa tatactttgg ttttagcaaa tcctcctttt aagggctcac ttgactacaa
    37501 ttcaacctct aatgaccttc ttgcaaccgt aaaaaccaaa aaaacagaat tactctttct
    37561 ttctcttttc ttgcgaactt taaaaccagg tggacgagca gcagttatcg tacctgatgg
    37621 tgtccttttt ggttcgtcta aagctcataa aggaattcgt caggaaattg tagagaatca
    37681 taagcttgat gctgtaatct caatgcctag tggtgtgttc aagccttatg ctggagtttc
    37741 aactgctatt ctcatcttta caaaaactgg taatggtggt actgacaaag tctggtttta
    37801 cgatatgaaa gcggatggtt taagtttgga tgataagcga caaccgatta gcgacaatga
    37861 tattccagat attatcgaac gctttcatca tcttgaaaaa gaagcagaac gtcagagaac
    37921 ggatcaatct ttctttgttc cagttgctga gataaaggaa aatgattatg atttgtctat
    37981 caataaatat aaagagattg agtatgaaaa agttgagtat gaaccaacag aggtcatctt
    38041 aaagaaaatc aatgatttag aaaaagaaat tcaagctggc ttggctgaat tagaaaaatt
    38101 actcaagtag ggaggtggct gtatgaaaaa agtgaagttg ggggaagtct tatctctaaa
    38161 aaaaggaaag aaagccactg tacttgctga acaaacaact ctaagccaac gttatattca
    38221 aatagatgat ttaagaaata ataataattt aaaattcact gaaagtttaa atatgactga
    38281 agcactccca gatgatattc taatagcatg ggatggtgct aatgcaggaa cagttggcta
    38341 tgggttatcg ggagctgttg gtagtacaat tacggtctta aaaaagaatg agcgatacaa
    38401 agaaaaaatt atatcagatt acttgggagt ctttttggaa agtaaatcgc agtatttacg
    38461 agatcattca acaggtgcaa ctattcctca tttaaacaag aatatattac ttgatttaca
    38521 attagaattg ctaggtatcg aagaacaaga gaacattatc tgtattctta atacgattaa
    38581 aaggcttatt actaaaagaa aatttcagtt agatgaacta aacttgctcg tcaaattccc
    38641 gatttaacga gatgtttggg gatcctttaa ataataacaa gaaatttgca gtaaaaacgg
    38701 gacaacagtg ttttaaattt tcaagtggaa aatttcttga taaacatgat agagtttttg
    38761 aaggttatcc tgcctatggt ggaaatggca ttgcttggaa aagtcgaaaa tatttaattg
    38821 ataatcctac tatcatcatt ggtcgtgtag gtgcatattg tggtaatgta agaactaccc
    38881 acggtaaggt atggataagt gacaatgcta tatatataaa agaatttaag aattccgatt
    38941 tcaatcttgt atttttatta gaattaatga aagtaattga ttttagtaaa tttgctgatt
    39001 tctcaggtca accaaagata actcaaaaac cattagaaaa tcagaaatat atcctccccc
    39061 ctctagccct caaaaatgag ttcgcagact ttgtagccct ggtcgacaaa tcacaattgg
    39121 caatccaaaa atctctggaa gaacttgaaa ctttgaagaa atctctgatg caggagtatt
    39181 ttggctgata ttctgccatt gtaattacgg taatgatttg ttataatact tcaaaggagg
    39241 aaatcagatg gtagtaaaaa caagaaaaca aggaaattca atcaccatta cgattccaag
    39301 tgaatttaat attccaagtg gtgttaaata cgaagcgaaa ttgttaccaa gtggtgagat
    39361 tatctttact cctgaagaat tggggcagca ggtttcttat gtatctgatg atgcctttga
    39421 cttaaattta gataaaatat ttgacgaata cgacgatgtt ttcaaagctt tggtggaaaa
    39481 atgacaatct atctgacaga aaagcaaatt gaaaaaataa atgctttagc aattcaacgg
    39541 tattctccaa atgagaaaat tcaaacagtt agttcttctg ccttaaatat gattgtgaac
    39601 ttaccagaac aatttgtctt tgggaagtct ctttatccaa caatttttga taaagcaacg
    39661 atactatttg tccaattgat aaagaagcat gtttttgcta atgctaataa aagaactgct
    39721 ttcttcgttt tggtcaaatt tttacaatta aacggctatc gtttttctgt aacggtagaa
    39781 gaagcagtaa aaatgtgtgt aaccatcgca gtagaagctt taactgatga aaaaatgaca
    39841 agctactcca aatgggtttc tgaacattct gttagagaaa aggtcaaaaa gtaacctagt
    39901 atgctggatt tgaatgagca caagaaaata aatgaacaga caatattaga attctgtaat
    39961 gcagaaactg atattgtctc tttttattga tgaataagaa agtgagaaat tatggaatca
    40021 aaagttacaa ttatcatgca agaaatgtta cctcttttaa ataatgaaca attactagcg
    40081 ttgagagaga gtttagaaca tcatctagta gacggaaaaa agcagcagaa gtattcgaat
    40141 aataacctgt tgcaactatt tattaccgcc aagcaggtag agggctgtag ctcaaaaaca
    40201 attcgttatt accagaggac gattgaaaac ttgtttaatg ctattaaaga gtctgtgaca
    40261 caactcacaa cagatgattt aaggagttat ttagcaaatt accagtctga aaaggattgt
    40321 agtaaggcaa atttagacaa tattaggcgt atattgtctt ctttttttgc ttggcttgag
    40381 caagaggaat atatcattaa aaatcccatt cgacggataa agaaaattaa gactgagcaa
    40441 aatgtgaagg aaacttatac tgatgaacat ttggaaatta tgcgtgataa ctgtgaaaat
    40501 ttgagagatt tggcaataat agacctacta gcatcgacag gtatgcgtgt aggggagctt
    40561 gtacagttga atcgttcaga tattgatttt gaaaacagag agtgtgttgt ctttggtaaa
    40621 ggaaagaagg agagaccagt atattttgac gctcggacga aaattcattt aagaaattat
    40681 cttaacgaca gaaaagatag tcaccctgct ctttttgtaa cgctagttgg aaaagcccag
    40741 agacttggaa ttgctggtgt agagattcgc ttaagaaagt taggagacaa actcggcata
    40801 caaaaggttc acccacataa gttcagaaga actttagcga ctaaggcaat tgataaaggt
    40861 atgcctatcg aacaagtcca aaaactgcta ggtcatagca agattgacac aaccttggcc
    40921 tatgccatgg tcaatcaaaa taatgtcaag cattcacacc aaaaattcat ctcttaaaag
    40981 caaatcccga tttaacgaga tgtttgggga aaataaaata tttgaaagca ttgataactt
    41041 atttgatatt atagatggtg ataggggcaa aaattatcct aaatcagatg agttgtttag
    41101 tgaggagtac tgtttatttt taaatacaaa gaatgttact aaaaacggat tttcattcga
    41161 tacaaagcaa tttatcacta aaacaaagga taaattactt cgaaaaggca aacttgagcg
    41221 ttatgatata gtcttgacaa caagaggtac tgttggaaat gtagcgtact acgatgaatt
    41281 aataaaatat aaacatttac gtataaattc aggtatggta atattacgtc ccaagacacc
    41341 aaatctaaat cagaaattta ttatccatgt tttaaggaat aataattata gtcgagtgat
    41401 atcaggaagt gctcagcctc agttaccaat tacaaaatta aaaaaaatac ttctccccct
    41461 ccccccacta gccctccaaa atgagttcgc agactttgta gtccaggtcg acaaatcaca
    41521 atttgcttgt gagatagcta taaaagtgtg gagaaatagc ttgaaattta gtataatata
    41581 gctaaactat ttgtttaaag tgagaaaaaa atgggaaatt ttagctttct tttaaaaaat
    41641 gacgaatatg aatctttttc aaaaccttgc attgaagctg agaatatgat tgctacatca
    41701 actgtggcta ctgcctttat ggcgcgtcgt gctttagagc aggctgtcca ttggatatat
    41761 agtcacgatt catatttaga agctccctat cgtgctactc tatcttcttt agtatgggat
    41821 gatgatttta gggatatcgt agattctgaa ctccacaagc agatagttct gttgattcgg
    41881 tggggaaacc atgctgctca tggtggtgaa attaaggaac gagaagcgat tttagctttg
    41941 catcatttgt atcagtttgt taattttatc gattattgtt acagcaatga gtttgtggag
    42001 cgttattttg atgagaagtg cttaccactt tcagcaaaca tcaaataccg agaaactcca
    42061 caatctatga taaagttaca agacagttta ccagaactgc ctgattttca tgaacagatg
    42121 gctgctcagt ccgtagaagt tcaagagact tatactgaaa aacgtgagac tgcagcgcaa
    42181 cggcaagatg tgcctttcca tattgatcaa ttatctgagg cagagacaag aaagctcttt
    42241 attgatatcg atctccgttt agcaggatgg atatttgaag aaaactgtcg tgttgagata
    42301 gccgttgatg gtctcaagca cggttcagga attggttact gtgactatgt actttatggt
    42361 aaaaatggga aaattttagc gattgtggag gctaaaaaag cctctgtcaa tccagaagta
    42421 ggggaagtac aggtcaaaga atatgctgaa gctttggaga aacatatcgg ctatcagcca
    42481 atttgcttta ttacaaatgg gttgaagcac tatatacttg atggtccgaa ccgccgccag
    42541 attgcaggct tttactctca agaagaattg caattagtga tggatagacg tcatcttcaa
    42601 aaaccgcttg aggatatttc tagtaaaatt agggacgata tttccgggcg tcactaccaa
    42661 aaacatgcca ttgcaagcgt ttgtgaagct ttctctaatc atcgtagaca ggcacttttg
    42721 gttatggcaa ctggggcggg gaaaactcgt acagcagttt ctctagttga tatcttatca
    42781 cgtcataact gggtaaaaaa cgttctcttc ttagccgata gaacttcctt ggttaagcaa
    42841 gcctatgatt cgtttagaaa attactccca gatctttccg tttgtaactt cttagaagat
    42901 aaagaaggag ctcaatcaag tcgtatggtc ttttcaactt atccgaccat gattggagcg
    42961 attagtggtc aagaagaagt aaatcaacgc ccttttactg ttgggcattt tgaccttatc
    43021 ataattgacg aatctcaccg ttctatttat cagaaataca agtccatttt tgattatttt
    43081 gatgcaagaa ttgtaggctt aacagctact ccgcgtcaag atttagataa aaacacctat
    43141 ggattcttta atttggagaa tggggttcca acatatgcat atgatttgga agaggctgtt
    43201 aaagacggat atttagtagc ctatcattct atcgaaacca aactgaaact acctacggat
    43261 ggtctacatt atgatgattt gtccgaagaa gaaaaggaac attttgatag caaatttgaa
    43321 gacgatagct gtgaaaaaga tattgatggg agtgtattta attcctttat tttcaataaa
    43381 agtacagtag aaattgtttt aaatgaactc atgacaagag gaattcagac agcctcgggt
    43441 gatgaaattg gtaaaactat tatttttgct aaaaatcatg atcatgcgga atatatcaga
    43501 ggtattttta acaaccgcta tcctgaaaaa gggagcgact atgctcaggt gattgattat
    43561 agtattaagc attatcagac cttgattgat gattttaaaa ttaaggagaa gtatcctcaa
    43621 attgcgattt ctgtcgatat gttagataca ggtattgatg taccagaggt tgttaattta
    43681 gtcttcttca agaaagtacg ctctaaaact aagttttggc agatgattgg tcgaggaacc
    43741 cgtctatgta aagatttatt tggacctgag caggataagg aaaacttctt ggtatttgat
    43801 tatggggaca attttgatta ttttcgtgca gatccaagag atggagaggg tcgtcacatt
    43861 gtttcgctga ctcagcgttt atttaatatc aaagtggact tgattcgaga acttcaggga
    43921 ctccaatacc aagaagatca gtttgcgaga gcataccgtc agcagcttgt ctcggaactt
    43981 caaggtcgta tagagagctt aaatgagttg gacttcaggg ttcgtatggt tttagataca
    44041 gtttatagct ataagaaatt ggaaagttgg cagaatctaa ctgctgttac aagtgaaacc
    44101 attcaaaaaa atctctctcc gcttttattt gatgaagata aagaagatga gatggcgagg
    44161 agatttgatt tgtggttgct tcatattcag ttggggcaac tgacagctaa atcttccact
    44221 gttcatattt cccaagtgat gaagacggct agagctcttt ctgctattgg caatatcccg
    44281 caggtttttg agcaggctga aattatcagg aaagtacagg agcctgaatt ttggaaagaa
    44341 gttaacttgt ctgatttgga aaaaattcgt cttgctattc gagatttatt acagtttttg
    44401 gataaaacag accgtaaacc ctactatgtt aactttgaag atcgtatact ctccactgtt
    44461 cacgagacca cagcattttt gcaggtcaac gatcttcggt cttacaatga aaaagttgag
    44521 caatatttga aaactcatct ggatgaggag tccatttcta agctatacca taataaaaag
    44581 ttgacatctg atgatatgct tgcacttgaa aaattgcttt gggaaaaatt aggtagtaaa
    44641 gcagactacc aaagtcatta tgaaaataag gcaattccga gattggttcg tgagattatt
    44701 ggcttagata gagagtctgc caatcgtatt ttttctaaat ttttgtcgga tgagaatctt
    44761 aatgccaggc agatttcatt tgtaaaattg attgtagact acattgtaga aaatggtttt
    44821 ttagagacga aagtgttaac gcaagagccg tttaaatctt atggttctgt tcaactactc
    44881 ttccaacacc aactaccagt acttcgtaat attgttcaaa tcattgaact tatcaataat
    44941 cgagctggag aagcggctta aattctaaag tgattgccat gctgagactc atttaaaatt
    45001 aaaaagagta gaaatttatg ctatatatga gaagttttat taggaagaat gtcatcgttt
    45061 tcctagaata cagtatcagt tgttaagtgg ttgataaatt tcaaagtaga tacttgtacc
    45121 acgatgtttg ttgatcgagt tattaacaaa agagctactt tgattttaaa gaaatagaaa
    45181 acaaaaagct gagcaagaat tcaattgcag gagaaaatga aataatactc aatgaaaatc
    45241 aaagagcaaa ctaggaaact agctgcaggc tgctcaaaac actgttttga ggttgtagat
    45301 aagactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac tgacgaagtc
    45361 agtaaccata tatacggcaa ggcgacgttg acgcggattg aagagatttt cgaagagtat
    45421 aaatcttctt aggataaagc aaaacgcata gtatcaaggg ttttcaacac ttgatactat
    45481 gcgttttctg atgttaaaga ctttctacca ggttttttaa aagcataatt gttagttgta
    45541 gtcatttatt attcttcaaa gaaaaatggt ggggcgaatt ttttcagttc ttcaaagcac
    45601 ttttgagcag tatctgcatc ttcacagatg ataagacaga catcattacc acaaagggta
    45661 gcgatagcgt cagggaagct caaagtatca atgatagaac caaaggattg agccagtcca
    45721 ggaagggttt ttagtaggac ttggtgttga actgggcgca tccagacaag ggcgtcttcc
    45781 atgtagagtt cgagacgttt ttcccatttt gagatggaac cattgttaag aacataataa
    45841 gcgctatctt cttcgcggac ttttgatagg ttcatatttt tgatgtcgcg tgagagggtt
    45901 gcctgggtta cttgaatgtc gttctcagca agaagggctt gcaactcagc ctgtgtatga
    45961 atcttgtttt ttgtgataag agcgcgtata agttggtggc ggtgttctga tttattcata
    46021 ataatgtaac tccttttagc aaggtaaggt aagcatggac tgagcgaggt cgacagtcaa
    46081 gtggtagtct gtattgtcac ggatggtgat ttcaaagtca gtagtataga ggactaaacg
    46141 gagagtgtct ccttctttta gcttgtaaat agttggctgc agttcaaatt gaacgtccat
    46201 ccattcatct gcagtaatat cctctactaa cagtaaatca tttctatttt gtaaattaag
    46261 gtaacctttt gtcacgactc gttgtgcctc tggtctaaat ggcaattcac agagattttc
    46321 caacatgtga tagcgaccgt tgtcaatggt tctagcactt aaaatagctg gataaggttg
    46381 taggtattta ttttgcccaa attctagcag ttgggcagat aagagcccct tgtttgtact
    46441 ggatttgata cgaagattga gctgagcgcg accgtttagg tggagatctt tagtcacagg
    46501 aaggttaata gtaatctgat tagctttccc ttgatagagc tctgtattga agatttggta
    46561 tgtcttacca tagcgctcaa aatccttatc tgggtactgg ttttgaatag cttgctcttc
    46621 ttgaccaagt gagaaggttt cacagttttc ttgcccaccg aagttatcaa gtgataacca
    46681 agtctgtgga gctgtattgt cctgccagat aacagtagga agttgaaagt ctgtttcctg
    46741 tcctagtaat ttcttggtca ataaggcatt tatggactca cggaagtcaa ttgattgcca
    46801 attgttcatg taaacatggg caccattatg gaaaaagaga tgcttgtgta tatgagtagg
    46861 aagagcatgg aacatctggt aaacatgaag tggtttgaca ttccaatcct gagaaccatg
    46921 agtaaagaca acctctgcct ttactttatg ggcattgagc agataattgc ggtcatgcca
    46981 aaactgattg tagtccccag tttttcggtc tagctgagct ttcacttttt ctaagtcagc
    47041 ttggtgagct tcattgccac ggatatagtc gccagctaag agattacgag aataggttaa
    47101 ctcagcaagg gagtcaaagt cctcacctgg ataaccacct gggctagtca ccagaccgtt
    47161 ttcacggtag tagttgtacc atgatgaaat tcctgcctcg gcaatgataa cttctaaacc
    47221 atcgactcct gtagtcgcaa gaccattgga catggtacct agataggaaa gtcctgttgt
    47281 agcaactttt ccgtttgacc aatcagcctt gacttgacgc tggcgcgtgt gatcagtaaa
    47341 ggcacggcaa cggccgttaa gccaatcgat gacattttta taagcctcga tttgctggta
    47401 gtctccatta gtcatgaaac ctgtcgagtc tttggtacca acacctgaga catagagatt
    47461 ggcaaagcct ctcggaagga agtagtcgtt tagtgtatag ctagagttga tgtgagttag
    47521 cttttcctca gcctctgcta taagctcagc tttaccttgg ggttggacga gatttagttg
    47581 aggtttctct agctcaatct tgtgaggaag tttaacctca agctcgccct ccatcttgta
    47641 gagagccttg tcactagcct tgtcattggt tccctgatga taagggctgg ctgtcatgat
    47701 ggcagggatt tttccatcaa aacgagggcg aataatgcta acctttacta ggtctgatag
    47761 ccctttttgg tcagtatcga cacgagactc aacgtaaacg acttcacgaa tgacatcctg
    47821 gttagaaaaa gtagccaaac tcttgccgtt aaagtagtgg tagtcattat cctccggaat
    47881 aagaccatca ctaacaagtt ggtcgataag agtatttcct tttttggtgc gagtattgag
    47941 taactgatag agattttcaa tcaagtcacc atatataatg ggaaatccag tttctttacg
    48001 aaaaacgtca ctatcttcga agtcaaccaa ataagaaaag cctaaaagtt gaaaagcaac
    48061 agtataaaaa atatctgctg tcagttcatc ttctgattga aaaaatgtca gcaggtctgt
    48121 ttttttatca gctgctagga tagaaagtgg gtagttggtg tcttgataag tgaaaaagaa
    48181 acgacgtaaa aaggtttcaa gtgagtcttt gtgattggct gtattttgta aatcaaagcc
    48241 acattttttt agttcagata agacattttc ttttggaaaa ttgatataac tatattgatt
    48301 aaaacgcata gaacctccat atagaatgac agttaaggtt attatatcaa aaaaaaagca
    48361 gaaagggaat tgttaacttc aaaaggaaat aatccaataa aaatgaataa agtactaaat
    48421 tcaatataga gaacagagta acaataagaa taaatagata gggtataaaa gttctaggag
    48481 a
//
LOCUS       DAVIME010000010        46590 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVIME010000010 DAVIME010000000
VERSION     DAVIME010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.010"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(613..1026)
                     /gene="ndk"
                     /locus_tag="VV588_000610"
     CDS             complement(613..1026)
                     /gene="ndk"
                     /locus_tag="VV588_000610"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU7082988.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(1137..4814)
                     /gene="rpoC"
                     /locus_tag="VV588_000611"
     CDS             complement(1137..4814)
                     /gene="rpoC"
                     /locus_tag="VV588_000611"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU7082989.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(4847..8458)
                     /gene="rpoB"
                     /locus_tag="VV588_000612"
     CDS             complement(4847..8458)
                     /gene="rpoB"
                     /locus_tag="VV588_000612"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU7082990.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            8874..8944
                     /locus_tag="VV588_000613"
     tRNA            8874..8944
                     /locus_tag="VV588_000613"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8906..8908,aa:Cys,seq:gca)
     gene            complement(9142..10473)
                     /locus_tag="VV588_000614"
     CDS             complement(9142..10473)
                     /locus_tag="VV588_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU7082991.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(10764..11588)
                     /gene="endA"
                     /locus_tag="VV588_000615"
     CDS             complement(10764..11588)
                     /gene="endA"
                     /locus_tag="VV588_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU7082992.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(11627..11815)
                     /locus_tag="VV588_000616"
     CDS             complement(11627..11815)
                     /locus_tag="VV588_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU7082993.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(11808..13091)
                     /gene="murA"
                     /locus_tag="VV588_000617"
     CDS             complement(11808..13091)
                     /gene="murA"
                     /locus_tag="VV588_000617"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU7082994.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(13115..13345)
                     /locus_tag="VV588_000618"
     CDS             complement(13115..13345)
                     /locus_tag="VV588_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU7082995.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(13403..14440)
                     /locus_tag="VV588_000619"
     CDS             complement(13403..14440)
                     /locus_tag="VV588_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU7082996.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(14424..14912)
                     /gene="coaD"
                     /locus_tag="VV588_000620"
     CDS             complement(14424..14912)
                     /gene="coaD"
                     /locus_tag="VV588_000620"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU7082997.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(14902..15441)
                     /gene="rsmD"
                     /locus_tag="VV588_000621"
     CDS             complement(14902..15441)
                     /gene="rsmD"
                     /locus_tag="VV588_000621"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU7082998.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQITKEIGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(15506..16498)
                     /locus_tag="VV588_000622"
     CDS             complement(15506..16498)
                     /locus_tag="VV588_000622"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU7082999.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(16609..17292)
                     /locus_tag="VV588_000623"
     CDS             complement(16609..17292)
                     /locus_tag="VV588_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU7083000.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(17348..18088)
                     /locus_tag="VV588_000624"
     CDS             complement(17348..18088)
                     /locus_tag="VV588_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU7083001.1"
                     /translation="MTIITSKANSVVKNTKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFTLENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQREEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            18122..18400
                     /locus_tag="VV588_000625"
     CDS             18122..18400
                     /locus_tag="VV588_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU7083002.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            18478..19404
                     /gene="yidC"
                     /locus_tag="VV588_000626"
     CDS             18478..19404
                     /gene="yidC"
                     /locus_tag="VV588_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU7083003.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(19479..20273)
                     /gene="pflA"
                     /locus_tag="VV588_000627"
     CDS             complement(19479..20273)
                     /gene="pflA"
                     /locus_tag="VV588_000627"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU7083004.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(20399..21649)
                     /locus_tag="VV588_000628"
     CDS             complement(20399..21649)
                     /locus_tag="VV588_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU7083005.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(21716..22543)
                     /gene="purR"
                     /locus_tag="VV588_000629"
     CDS             complement(21716..22543)
                     /gene="purR"
                     /locus_tag="VV588_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU7083006.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(22810..23751)
                     /locus_tag="VV588_000630"
     CDS             complement(22810..23751)
                     /locus_tag="VV588_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU7083007.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(23741..24997)
                     /locus_tag="VV588_000631"
     CDS             complement(23741..24997)
                     /locus_tag="VV588_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU7083008.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(24999..25661)
                     /locus_tag="VV588_000632"
     CDS             complement(24999..25661)
                     /locus_tag="VV588_000632"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU7083009.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(25624..26280)
                     /locus_tag="VV588_000633"
     CDS             complement(25624..26280)
                     /locus_tag="VV588_000633"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU7083010.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(26291..27169)
                     /gene="rsgA"
                     /locus_tag="VV588_000634"
     CDS             complement(26291..27169)
                     /gene="rsgA"
                     /locus_tag="VV588_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU7083011.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(27171..28043)
                     /gene="rsmA"
                     /locus_tag="VV588_000635"
     CDS             complement(27171..28043)
                     /gene="rsmA"
                     /locus_tag="VV588_000635"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU7083012.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(28429..28575)
                     /locus_tag="VV588_000636"
     CDS             complement(28429..28575)
                     /locus_tag="VV588_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083013.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDKNMTNHLLLVQILVHGYLLDFA
                     SIEG"
     gene            complement(28568..29209)
                     /locus_tag="VV588_000637"
     CDS             complement(28568..29209)
                     /locus_tag="VV588_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083014.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(29211..31241)
                     /locus_tag="VV588_000638"
     CDS             complement(29211..31241)
                     /locus_tag="VV588_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU7083015.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(31318..31614)
                     /locus_tag="VV588_000639"
     CDS             complement(31318..31614)
                     /locus_tag="VV588_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU7083016.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(31934..32833)
                     /locus_tag="VV588_000640"
     CDS             complement(31934..32833)
                     /locus_tag="VV588_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7083017.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(32905..33465)
                     /gene="rnmV"
                     /locus_tag="VV588_000641"
     CDS             complement(32905..33465)
                     /gene="rnmV"
                     /locus_tag="VV588_000641"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU7083018.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(33465..34238)
                     /locus_tag="VV588_000642"
     CDS             complement(33465..34238)
                     /locus_tag="VV588_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU7083019.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPMIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIRLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(34543..35436)
                     /locus_tag="VV588_000643"
     CDS             complement(34543..35436)
                     /locus_tag="VV588_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU7083020.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEVTPEY
                     KLETTPGGDKGGNIGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRLVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(35720..35854)
                     /gene="rpmH"
                     /locus_tag="VV588_000644"
     CDS             complement(35720..35854)
                     /gene="rpmH"
                     /locus_tag="VV588_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU7083021.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(35999..37213)
                     /locus_tag="VV588_000645"
     CDS             complement(35999..37213)
                     /locus_tag="VV588_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU7083022.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQMKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(37369..37662)
                     /locus_tag="VV588_000646"
     CDS             complement(37369..37662)
                     /locus_tag="VV588_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083023.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            37811..38263
                     /locus_tag="VV588_000647"
     CDS             37811..38263
                     /locus_tag="VV588_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU7083024.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(38298..39686)
                     /locus_tag="VV588_000648"
     CDS             complement(38298..39686)
                     /locus_tag="VV588_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU7083025.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELHRQL
                     KAYERHKERNKS"
     gene            39752..40714
                     /locus_tag="VV588_000649"
     CDS             39752..40714
                     /locus_tag="VV588_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU7083026.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLTMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(40711..40902)
                     /locus_tag="VV588_000650"
     CDS             complement(40711..40902)
                     /locus_tag="VV588_000650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083027.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDRTDEVS
                     NHTYGKATLTWFAEIFEEY"
     gene            complement(40966..41976)
                     /gene="ccpA"
                     /locus_tag="VV588_000651"
     CDS             complement(40966..41976)
                     /gene="ccpA"
                     /locus_tag="VV588_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU7083028.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(42401..43000)
                     /locus_tag="VV588_000652"
     CDS             complement(42401..43000)
                     /locus_tag="VV588_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083029.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVAVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(43002..44099)
                     /locus_tag="VV588_000653"
     CDS             complement(43002..44099)
                     /locus_tag="VV588_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU7083030.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(44099..44836)
                     /locus_tag="VV588_000654"
     CDS             complement(44099..44836)
                     /locus_tag="VV588_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083031.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(44838..45722)
                     /locus_tag="VV588_000655"
     CDS             complement(44838..45722)
                     /locus_tag="VV588_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083032.1"
                     /translation="MDMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELVAFFQSIY
                     PNPLSNQEIDQLLQFDKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVQDLKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(45709..45903)
                     /locus_tag="VV588_000656"
     CDS             complement(45709..45903)
                     /locus_tag="VV588_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083033.1"
                     /translation="MKKAFLYLFIGLSLVVWLVEMFTGWFDQALLRQFIRGAWGLGFM
                     IFIAFPMGMEWLKGEYHGHD"
     gene            complement(45900..46091)
                     /locus_tag="VV588_000657"
     CDS             complement(45900..46091)
                     /locus_tag="VV588_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083034.1"
                     /translation="MKNKMIVAMSLVAAGVMTYLMFSGLDEDFYHFPWELFAGFGMMS
                     WLIREGLKLVSDVKKEFEK"
BASE COUNT        13335 a        10802 c         8833 g        13620 t
ORIGIN      
        1 ttattccatg ttattttgag gaagatattg tgaaagtcaa agatgatgat aaagttgagt
       61 ggaatttgtt agaatttcaa aaatttagag catttttgac ttagtaatct gtgttgaagg
      121 ctcaaaacct atggtaaaaa agtaactttg aaaacgtatt gcctccaaag atttagttaa
      181 ataatgattt aacacaaaaa gaaattattg aagttctgga aagatgttgt ttcagtattg
      241 agaaaaggtg ggaaaaactt gcgattttca cagagaaagg aagaaaaagt atagaaatat
      301 agtcaattga aacaagaaca ggataaaaga accttttgtg ccatattttt ctcctttcgc
      361 tttacaattg gattgaacac ctttattgta tcgcgtttgg agtttttttg gtataacctt
      421 cgacgcgcac ccgcatagcg ggtgtttttt tgtctcgcac ctaacggagc gagacgaact
      481 aatagtcact taatcaaaaa acgcaccata tcaaaaacta aaaagtttga tatcatgcgt
      541 catgtcttaa actaattgac tatactttct attcaaatga gcttttaacc aattgattga
      601 gccaatccac tcttaaaacc aaagagcaat ttctcgctta gctgactctt ctgaatctga
      661 accatgtaca acattttgga taacctcatt ttctccagca gcttttgcaa agtcacctcg
      721 aatagtgcct ggtaaagctt cttctggacg agttgcaccc atcatggtcc gccaagtttc
      781 gattactttg ggaccagaaa tgacacccac aagaactgga cctgaagtca tgaattcacg
      841 aatcggtggg taaaaactct gaccaaccaa gtcctgatag tgctggtcaa tcaactcttc
      901 tgaaacctgt gaacgaaact ccaatttttc gattgtaaat ccacgttgtt cgatgcgctt
      961 taacacttca cccactagcc ctctttttac accatctggt ttgatgataa agaatgtttg
     1021 ttccataccc gtctcctttg tcagcttctt tcttttattt taccacattt cgtggaaaaa
     1081 tggagaaagt tttcagaaga gagaatgaga gaacccgagg gttctctcat tctctcttat
     1141 tctactgttt cttccacagt ttcaacggca gtatccacaa ctacttctgt tgtttcttca
     1201 tttccttctt cctctactgg aggattaagg tattcttctt cgttgacagc atgtggttca
     1261 aggttacggt aacgggccat accagtacca gctgggatga tcttaccgat gataacattt
     1321 tctttaagtc caaggagatg gtctttctta ccacggatag ctgcgtcagt aaggacacga
     1381 gttgtttcct ggaaggaagc cgctgacaag aaactgtttg tttcaagtga ggctttggta
     1441 attcccataa ggactgggcg acctgtcgct ggaactccac ctgcgataag gacatctttg
     1501 ttggcatctg taaagtcatt gatatccatg agggtaccca tgagaagatc tgtatcacct
     1561 ggatccatga cacggacttt acggatcatt tgacgaacca ttacctcgat gtgtttgtca
     1621 ccgatttcta ccccttggct acggtaaact ttttgtactt caccgagaag gtacgtttca
     1681 actgacaaga catcacgaac tgcaaggaga cgttttggtt ggatagaacc ttctgtcaga
     1741 gcagcaccac gcgctacttg gcccccaact tcgacacgca tacgagctgt aaatggaacg
     1801 acatattcac cttcgccagt ttcaccctta acaaagactt tcttggtacg agttgatgca
     1861 tcctcttcga tagcagtaac ttgtccttta acctctgtga taaccgcttc ccctttagga
     1921 ttgcgggctt caaagatttc ttggacacga ggaagaccct gagtgatatc ggtatttgag
     1981 gcaaccccac ctgtgtggaa ggtacgcatt gtaagctgtg taccaggttc cccgatagat
     2041 tgggcagcga ttgtaccaac tgcttcacca acttcaaccg catcaccagt cgccaagttg
     2101 ataccgtaac agtgacggca gacaccgtga cgagtgttac atgtaaatac agaacggata
     2161 gtcacttctt ccacaccagc attgacaatt tcacgcgcct tgtcttctgt aatcaattca
     2221 tttggaccaa taatcactgc accagtttct ggatgtttaa cagttttctt agtgtaacga
     2281 ccgttgagac gctcttcgag agactcgatc atctcttttc cttctgcgat agaacggatc
     2341 aagagaccac ggtcagttcc acagtcgtcc tcacggatga taacgtcttg ggcaacgtcg
     2401 accaaacgac gagtcaagta acctgagtcg gctgtcttaa gggccgtatc ggtcatacct
     2461 ttacgagcac cgtgagttga gaagaacatt tccaataccg acaaaccttc gcggaagttt
     2521 gaaaggattg gcaattccat gatacgtcca ttcggagcag ccatcagacc acgcataccg
     2581 gcaagctgtg agaagtttga gatgttacca cgggctccag agtccatcat cataacgatt
     2641 gggttcttag gatcttgatt agcaatcaag cgtttctcaa gtttttcacg ggcagcacgc
     2701 cattcagctg taacagcatt gtaacgctcg tcgtctgtga tcataccacg acggaattgt
     2761 ttggtgattt gttcgacacg tttgtgtgat tcttcaatga tttcagcctt gtcatcaacg
     2821 actgggatat cggcaatacc cactgtcaat cctgcaagag ttgagtggtg gtaaccgagg
     2881 ttcttcatgc ggtcaagtag ggcagaagtt tctgtcgtac ggaaacgttt gaagatttca
     2941 gcgatgatat ttccgaggtt tttcttcttg aatggagggt tgagctcaag attgctgata
     3001 gcttccttga tatctccacc aagtggcaag aagtatttag ctggaacacc ttctgtcaag
     3061 ttggcattgt ttggttcttg caagtatggt agcccctctg gcatgatatc gttgaagaga
     3121 attttaccaa ctgttgtaag caagacctta tgtctttgct cttctgtcca aggcttgttg
     3181 aggctgtctg ttgcgatacc aacacgtgag tggaggtgaa cataaccatt gcggtaagcc
     3241 ataaccgctt cgtcacggtc tttgaagacc attccttcac cttcgcgacc agcttcttcc
     3301 atggtcaagt agtagttacc caaaaccatg tcctgagatg gagtaactac cggtttccca
     3361 tctttcgggt tcaagatgtg ctcagcagct agcatgagga tacgagcttc tgcttgtgct
     3421 tcttctgaaa gtggtacgtg gatggccatt tggtccccgt caaagtcagc attgtaggct
     3481 tcacagacaa gtgggtgcaa gcgaagagcc ttaccatcaa tcaagactgg ctcgaaggct
     3541 tggataccca aacggtgaag ggtcggtgcg cggttcaaaa gcactgggtg ttctttaatc
     3601 acttcttcaa ggatatccca gatacgctca tctccgcgtt ccaccaagcg tttagctgct
     3661 ttgacgtttt gcacgatatc acgggcaacg atttcacgca tgacaaatgg tttaaagagt
     3721 tcaatcgcca tttcacgtgg aacaccacat tggtacatct taagagttgg accaacggcg
     3781 ataacggaac gtcctgagaa gtcaacacgt ttaccgagca agttttgacg gaagcgtccc
     3841 tgtttacctt taagcatgtg gctcaatgat ttcaatggac ggctacctgg tcctgtgatt
     3901 ggacgaccac gacgaccatt gtcaatcaaa gcgtcaactg cttcttgaag catacgcttc
     3961 tcattttgaa cgatgatacc tggtgcattt aactcaagca aacgagccaa acggttgtta
     4021 cggttgataa cacggcggta aaggtcattc aagtcagatg aggcaaaacg gccaccatcc
     4081 aactgcaaca ttggacgaag atctggtggg ataaccggaa ggatgttaag aatcatccat
     4141 tcaggtttgt ttccagactt gtaaaaggca tccaaaacat ccaaacgacg gatggctttg
     4201 acacgttttt gtccagtagc tgttttcaat tcttctttga gttcagcaat ttctttttca
     4261 agatctactt gcttcaaaag gtcttggatg gcttccgcac ccatcttggc aacaaatgaa
     4321 ccataaccat attcacgcaa gcgctctcgg tattcgcgct ctgtcatgat agacttgtgc
     4381 tcaagtggtg tatccttagg atcaatcacc acataagccg caaagtagat aacttcctcg
     4441 agggcacgag ggctcatatc aagggtcaag cccatacggc ttggaatccc cttgaagtac
     4501 cagatgtgag atacaggagc tttcaattcg atatgtccca tacgctcacg acgaactttc
     4561 gtacgcgtta cttcaacccc acagcggtca caaacaattc ctctgtaacg aatgcgtttg
     4621 tacttaccac aagcacattc ccagtctttt gtaggaccaa agatcacttc atcaaagagt
     4681 ccttcacgtt ctggtttcaa ggtccgataa ttgattgttt caggtttttt gacttctcca
     4741 taagaccatg aacggacttt acttggagaa gctagggtga tttgcatact tttaaaacga
     4801 tttacatcaa ccactatttc ttccctttct attctaagtg aactgcttat tcttgttcag
     4861 cagcttcttc tgttgcttcc gcttttgttg ctttctcagc ttcttcagct tcaaaggctg
     4921 ctttagcctc ttgggctgct ttttcgcggg ctttttcaag gtcatctacg tggatgacat
     4981 cttcgtccat tccttcatcc aagtcgcgaa gttccacttc ttggtcatct tcgtctagga
     5041 cacgcatgtc aagaccaaga gattgcaatt ctttgacaag aactcggaag gattctggaa
     5101 cacctggttt tggaattggt ttgccttttg taatagcttc ataggctttc aaacgtccgt
     5161 tgatatcgtc cgacttgtaa gtcaagattt cttgaaggac atttgacgca ccgtaggctt
     5221 caagagccca aacctccatc tcaccgaaac gttgtccacc aaactgagct ttacctccga
     5281 gtggttgttg ggtaacagtt gagtaaggtc cgactgaacg cgcatgcaat ttatcgtcaa
     5341 ccatgtggtg gagtttaatc atgtacatga ctccaacaga aacacggtta tcaaatggtt
     5401 cacctgtacg tccatcgtaa aggattgtct tggcatcgct atccatacct gcttctttaa
     5461 cagttgacca aagatcttca gagcttgctc catcaaagac tggtgtcgca atgtgaatac
     5521 caagagtacg agctgccata ccaaggtgaa gctccataac ctgaccgata ttcatacgtg
     5581 atggcacccc aagtgggttc aacatgatgt cgactggagt tccgtctgga aggtaaggca
     5641 tgtcttctac aggaacgata cgagagacaa cccctttgtt tccgtgacgt ccggccattt
     5701 tatctccgac cttaatctta cgtttttgag cgatgtaaac acgaaccaac atgttaacac
     5761 ctgattgcaa ctcatctcca tttacacgtg taaagatctt aacatcacga acgacaccat
     5821 cggcaccgtg tggtacacga agagaagtat cacgcacttc acgagacttg tctccaaaga
     5881 tagcgtgcaa gagacgttct tcagctgaaa gatctttctc acccttaggt gttactttac
     5941 ctacaagaat atcaccttct ttaacctcag caccaatacg gataatcccc atttcgtcaa
     6001 ggtctttgag ggcatcttca ccaacgtttg gaatttcgcg agtgatttct tcaggcccaa
     6061 gctttgtatc gcgcgtttct gattcgtatt cttcaaggtg aacagatgtg tagacatcgt
     6121 ccttcaccaa gcgttcgctc atgataacgg catcctcgaa gttgtaacct tcccaagtca
     6181 tgtaggcaac gattgggttt tgtccaagcg ccatttctcc attttccata gaaggtccgt
     6241 cagcgatgaa atcgcctttt tcaacgacat caccaacttt tacgagagtg cgttggttgt
     6301 aagcagtacc tgagtttgaa cgacggaatt tttggatgtg gtaaacatcc aatgaaccat
     6361 cttcacgacg aacttctacc ttgtcagcat ctgcgtaagt aactttacca tcatactgag
     6421 caatcacagc cgcaccagaa tcgtgggctg cttggtattc cataccagta ccaacgtaag
     6481 gtgcctgagg attaatcaat ggcacagcct gacgttgcat attggctccc atgagggcac
     6541 ggttggagtc atcgttttcc aagaaaggaa tacatgctgt cgcaacggca actacctgtt
     6601 ttggtgaaac gtccatgtag tcaacaatat tagctggata ctcttggttg accccttggt
     6661 gacgtcccat gacaatcttc tcagcaaagg ttccatcttc attcagacga gagttagcct
     6721 gagctacagt atattcatct tcttcatcag ctgtcaacca aacaatttcg ttcgtgacaa
     6781 cacctgtttc acggtcaacc ttacggtatg gtgtttgaac aaaaccatat ttgttcaagt
     6841 gtccgtaaga tgacaagtta ttgatcaaac cgatgttagg tccttcaggt gtctcgattg
     6901 gacacatacg accatagtga gtgtagtgca cgtcacgtac ttcatatccg gcacggtcac
     6961 gagtcaaacc accaggtcct aaggctgaca aacggcgttt gtgagacaac tcagaaagcg
     7021 ggttgtgttg gtccatgaac tgtgacaact gtgatgaacc aaagaattct ttaactgcag
     7081 ctgttacagg acggatattg ataatttgtt gtggtgtcaa gacttcattg tcctgaacag
     7141 acatacgttc acggacatta cgttccatac gagaaagtcc caaacgtact tggttggcaa
     7201 gcaattcacc aaccgcacgg atacgacgat ttccaaggtg gtcgatatca tctacacggc
     7261 caagtccttc agccaagttg aggaagtagc tcatctcagc aaggatatct gcaggagtca
     7321 ccgtacgaac cttgtcatct gggttagcat taccaatgat cgttacgacg cgatctggat
     7381 cagttggagc aataaccttg aatttttgaa gaacaacagg ctcagtcaca acggctgcat
     7441 cgtttgggat gtagacaatc ttgttcaagt cgccatccaa atggctttca atgctttcaa
     7501 tcacgctacg agtcataatc gtaccagctt ctaccaagat ttctccagtt tcagggtcta
     7561 ccaatggctc tgcaatggtt tggttgagca aacgtgtttt aacattgagt tttttattga
     7621 ttttgtaacg accaactgct gccaagtcat aacgacgtgg gtcaaagaag cgagctacaa
     7681 gcaagctacg tgagctttca gccgtcttag gctcacctgg acgaaggcgt tcgtaaattt
     7741 ctttcaaggc ttcgtctgta cgagagtcca ttggattctt gtggatatct ttttcaacag
     7801 tgttgcgaac caattcgctg tctccaaaga tatcaaagat ttcatcatca cctgagaaac
     7861 caagagcacg aaccaaggtt gtaaatggaa tcttacgagt acggtcaata cgagtgtagg
     7921 tgatatcttt tgagtcgctt tcaagttcca accaagctcc acggttaggg ataacagttg
     7981 aaccatagcc caccttacca tttttgtcta ctttgtcgtt aaagtaaaca cctggtgagc
     8041 ggaccaactg agaaacgata atacgttcac caccattgat gatgaaagta cccatttctg
     8101 tcatgattgg gaaatcacca aagaaaactt cttgggtctt gatttcgcct gtttctttat
     8161 tgatcaaacg gaaggttaca aaaattggtg ctgagtagct agcatcgtgg atacgagctt
     8221 cttctagcgt gtattttggt tccttgattt catatccaac aaattccaac tccattgtgt
     8281 ctgtgaagtt tgaaattggc aatacatctt caaacacttc cttaagaccg tggtctagga
     8341 aagctttgaa tgagtcagtt tgaatttcaa tcaaatttgg taagtcaaga acttctttga
     8401 ttcttgaaaa actacgacgg gtacgatgtt tcccgtattg aacgtcatgt cctgccaaga
     8461 tgattctcct ttgtaaataa gttccaagcc ttgtcaatca ggcttttcta atcgtcatat
     8521 ggttgtaaac cccttatcac cgtgtcctct tgacgaattt tcagaatctt taagcctctg
     8581 ttacaaatgc tcataatctt gaaaaaaagc acaaaaagag cagctaaatc tgactttttc
     8641 agaagattta actgctgtga gccttgtctg gacaatattt cagacaaaac ctacgacaaa
     8701 tgattaccca tattataccc tatttagcta gatttttcaa ggggtttcag taggtttttg
     8761 gtaaattttt tcccatagaa aacttggcat cacattcgaa tcacgctatg gtacaaaaaa
     8821 ctgaaaaaac tattgactga aaatcatttt caaggtataa taataaacgt taaggcggta
     8881 tagccaagtg gtaaggcacg gctctgcaaa agcttgatcg tcggttcaaa tccgtctacc
     8941 gccttctata acttgattta tcaggtttca aatgaacaga aagcccaatt tgaagggctt
     9001 tttttatttt ccctcgaata aatacgtata actttaaaaa cttttggagc gagtttgtgg
     9061 cagagttctt tccatggcat aattcccttt tgaaatcaat tgaaaaaagc ttcgtcacgc
     9121 ctggtgacaa aagcctctag tttattctgt ttcttcttct atttcgactt ctgtgatttg
     9181 gacttttacc ttggtaacac gtccattctt cactttatca ttggttaaga taaactgttt
     9241 gttttggctg accaattcat agctgagttt ctcagtcgtt ggaatggttc ccactcctgt
     9301 caaataataa ccagcgatgg tatcaacgtc atcactttcc agctcaacat caaagtaatt
     9361 attgaaatca ttgagggtca tagttccttg aacaatgtag gtatcctcgc caatctgatg
     9421 aacatctatt gctgctttgt ccgtttcatc atcaatttca ccaacaattt cctctaagag
     9481 gtcttccaaa gtcactaaac cagccatacc accgtattca tccagcaaga ttgccatttg
     9541 tctttgggta tttcgcagtt cttttagcaa gtcatccaca aaaatagttt caggtacaaa
     9601 aagtggatct tgtaaaattc tcttccaaac aatattgtca aaaccgtcca caaagcctgc
     9661 cttaaggaga ctcttggtgt gaatgattcc aattacattg tccttatccc catcataaac
     9721 cgggatacga gaataatttt gttttaaaat actttggata atggcttgac tatcatcctg
     9781 aatatccacc ataaaggcat ccgttcgagg aaccataacc tctcgtgcca tcagttcatc
     9841 gagcgaaaag acaccttgta gcatctcaat ctcatcagca tccaatgttt cttcactatt
     9901 tgtcagcata taggcaattt catcacgggt cattttttca tccgcatcat cgaatgacat
     9961 aggagtcaaa tggctcaaga aattggtcga agcagctaaa agccaaacaa aaggactgac
    10021 tagttttccg atcccaatga taaccggcgc tgtacgaatt gccaaggcat cctttagatt
    10081 aagagcgatt ctcttaggat ataattcccc aaaaacgatg gaaatatagg tcaaaaatgc
    10141 caaggataga aaagttgcca cggcttgtgc tgtttcgcca ttcccaagcc aagaggcaat
    10201 cacacgtcct agagtatcag ttaaactcgc ccctgataag attgtaatca gggtgattcc
    10261 tacctgaatg gttgataaaa agtggttagg attttctagt accttcagca ggcggatgta
    10321 gcgtctgtct ccttcttccg ccttttgttc aactcgggca cgattaagag aaaccatggc
    10381 catttctgtg gctgagaaaa aggcatttaa taccgtcaag ataaacaata aaacaaattg
    10441 tagcaacaaa ttctgactac ttgggtcttc catagttctt ctcctaaaat agtatcttat
    10501 cctttattat atcacaaaat ttaatccaat acatattatt tttttcttag cgtaacttcc
    10561 atctctctcc caaaactgga agttagtcta agacggattt ccactgattt cacgcgtttt
    10621 tctcatacta aaagctaggt tgtgggaaac tggaagttag ttttagaagt tactattttt
    10681 tcttagtacc tattctagcc ctgcttaaac tagtaaaaag aactcctaca tccataagtg
    10741 acataggagt ttaggcttat cttttactga gttacagtta cttctccagt tcggtaatcc
    10801 agttgaagtc ccttttgaac attgggaact agaacattga attccaattc tccatccgaa
    10861 gacttggctt caatctgtga agctgaggga actaaatcct cgtttgaagc gtagtaaagg
    10921 gttacacggt aacggacacg cttgttttgg tccaaggctt tacgcacctt gctttcatag
    10981 tagttttgac cagtcgaata ctcggcttgt gcctgatttg cccaggctgt ctgaacagca
    11041 atgtttttag gattgcttgt tgaggcatca aaaccatcca aaccaccgat taaggcatag
    11101 cctaacaaat gacctctatc gactgcatgg gtataagagc cctttagatt cttgacctga
    11161 tgccaacctg gaggagtcca agaagttgaa ccattcccag tttctttacg attcttgtac
    11221 tgacgagtgg ccttagacaa gagggcatta gctacggttg gaacagtttc cttgcccact
    11281 gtctttgttt tattgtcagc gtagggctta cttgaaacct tggcatctag atttgtttta
    11341 ttaccattga cgataaaagc acctgagcca ttccactcca gactcccctt tatttgactc
    11401 ttgactgcgt ctgttaagac actctctgcc aatgcttgac taggagcttc agacgcttgt
    11461 tttttctgac taagattggt tttgggacta ttaggtgccg actgcatctg cttgatataa
    11521 tagctccctg tagacaaaag caataacact agcagtccga ttagtgtctg tcttgttttt
    11581 ttgttcatat ttctccttat ctttagaaaa aggctggttc tccagcctaa tttcctgtaa
    11641 atttatgaat caattcctgc cattttgctg gagacaggat agcccatgga tcttgaccct
    11701 tgcccaagat tccataacct accattagac cgattcctag agccagagta cctaaaatca
    11761 gtactatgat gactaaaagt aaacgattga ttacgtagct tgatttctta ttcatcttca
    11821 tcgcttgcct caatccgctg aatcttagca cctagctgcg ccaacttctc atggaaaccg
    11881 tagtaacctc tatccaagtg aaccaattta ccgaccacag tttctccctg tgctaccaaa
    11941 cctgtcaaaa tcaaggctgc actggcacga aggtcagttg aaagaacttc tgctccctgc
    12001 aaaggctgtc caccaacaat acgagctgta tcacggataa tctcagaatg caagcccatg
    12061 cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa ctgtctccac catggttgat
    12121 tcgccttttg caactgtcat caaggctgta aattgagcct gcatatctgt tggaaatcct
    12181 gggtggggca aggttttcac atgaacagct tttagatttt ctagttgaga acgaacacga
    12241 attccttcgt cttcttcaat tacttcaaca cccatttcaa gtaacttggc aatcaaggga
    12301 cggttgtgct cccagacagc gtctcgaatc aagacatcac caccagtcat ggcagcagct
    12361 accataaagg ttcctgcttc gatacggtct tggactacat tgtgagtcgt accatgaagt
    12421 ttctcaacac cagtaatggt tatagtctct gtaccagcac ctttgacctt ggctcccatt
    12481 tcattaagga gaatggctaa gtcaacaatc tcaggctcac gcgcagcatt ctcaatcact
    12541 gtcaccccat cagccagagt cgctgccatc atcaagttct gcgttgcacc aacacttgga
    12601 aagtccatat agatatgagc accatgcaag cgttctgcct tggcttcgat gtaaccagct
    12661 gtctgactaa tcttaacccc catagcttcc agacctttca aatgaagatc aataggacgg
    12721 ctaccaatcg tacaaccacc tggcatggat accttggcat gacccacacg ggcaaggatt
    12781 ggccctaata caacgatgga ggcgcgcatc ttgctgacat acttgtaagg ggcttcctca
    12841 gtgatgtcgc cagtagcatc caccttgaca agatgagctt cctcatcaaa gtcaaccttg
    12901 gcattcaaac caccaactac ctgattcata ataaagacat ccgacaaaat cggaacattc
    12961 tgcaagacgg tctttccttc acttgctaga atagtcgctg ccaacaaggg taagactgca
    13021 ttttttgctc cctcgatcgt cacgcttcct accagacgat tatcgccacc ttgaaccaca
    13081 attttatcca tactcgtttc ctttactctt gatttcataa taatcctcta agcgcttctt
    13141 gccacaaatg atacaggcta ataaagaaag aactcaggat gtagcctatg acaatgctaa
    13201 aaaaggctac taataaacga acttttcttg tattctcatc tgtcactttt aaaaccttct
    13261 cccatctaac aagatccttt aaaaggtaaa aactcacata aataaagagc atatgactac
    13321 ttagagtgaa taataattga accatttgac tattatacca tcttctctgt ttgtgcgcta
    13381 gtttggaaac ttcactcaaa aattagggat tgtttttcaa gtaatcaatc gcatcttgta
    13441 gggttttaac gggcacgatt ttcatatccg tcttgattgt tttagccgct tctagggctg
    13501 tttggtagtt gtttttcgcg tccggatgcg ccttttgttc ttcttcgcta acagggttat
    13561 caggagcaaa gaaaatagca gcacctgccc tagccgaagc tacaaccttc ttatcaatac
    13621 ctccaatgtc tcccacatta ccatcgcggt caatggtacc tgtaccggca acaatacgac
    13681 cattacgaag atctgggtga gctatttgag tatagatagc tagactaaac atgagaccag
    13741 cacttggacc gccaatacca gctgttgaaa agctaattgg gacattgctg attacctctg
    13801 tacggtcaat caagccgatt ccaattccat ttttgccatt ttccaaggtg ataatctttc
    13861 cttctgcaga cttggtttgc ccatcctctt cataggtgac cttgacggaa tcccctaatt
    13921 tttgagaact gacgtaatca atcaagtctt tggaactatc aaaggtctga tcattgactg
    13981 ctgtgactgt atcagagata ttgagaatcc ctttaaaggt tgaattatcc gtcacattca
    14041 aaacataaac tccaaagtac ttgagttcga tatccttacc agctgttttt agtccttgat
    14101 acttggccat attttgcgat gtttgcatgt agaattgatt gattcgcata aattcaacat
    14161 cggaagaacc acctgtagtc tcctgagcac tacgaatatc tgtaaaaggt gtcaaccaag
    14221 cataaatcat atgagctaaa gtggcatgtt gaacaccaac cgtaacgaat tgataggcac
    14281 cagcttcctt atcttctgtg tcatttattt taaggacttg gcgaatatct tccgaaccac
    14341 ctggaacctc tatataataa ggcaagggca ctacaaatgc caagaaagtc acaatcaagg
    14401 ccgcaatgac gtataagggc catctaatct tttttttcat ttcttatttc ctccaaaata
    14461 ctctcgggaa catagcaggc aatatcctga ccaaacttca aaagctctct aacgcctgat
    14521 gaactgatat agagatgttc aggtcgacta tgtaaataaa tagtctctat atcagaagac
    14581 agctgatgat tgtagtaatc aaaactggct tcatattgca aatccgacgc attcctcaaa
    14641 ccacgcacta gacaagtagc acccaatctt tttgcaacat cgaccaccaa ttcatcatga
    14701 gaagccacga cttcaacatt ttccagatgt cccaaagcct tttctagccc ccgtttacga
    14761 ttttcgatag gaagaaatcc ttgtttgtgg ggattaaaaa aaataccgac atagagctta
    14821 tcaaagagtc tgctcgcccg ttcaatgata tccagatgcc catttgtcat cggatcaaat
    14881 gagcctgtga ataagccaat cttatctgac atagactgtc accttactaa ttccataaat
    14941 cttttccttc cagataccca gacaggcaat ttcttctgga agttcaacgg ccttatccgt
    15001 ctcgcacaca accataacat cttcagaaaa aagctctctc tcagccattt tttcaatatc
    15061 tgctacgatt tgttccttgg tatagggagg gtctaagaaa acgaggtcaa attccccaga
    15121 tacctgttcc aatgcccttt ctgcatccat cttgaggagt tgaaattttc caatttcctt
    15181 ggttatctgg atattttcag ccacgatggt ctgagcctta cggtctcgct ccaccaaaac
    15241 agcactggac atgccacgcg atactgcttc gatagataaa ccaccactac ctgcataaag
    15301 gtccaagact cgtccccctt caaagtaggg accaatcata ttaaaaatgg ctcccctaac
    15361 cttatccgaa gtaggtcttg tcgtcttgcc ttctagtgtc ttgaggggac gtcccccata
    15421 gattcctgat acgattttca tactgtttat tataccaaat tatagacaaa aagagaaaga
    15481 aaaccgaacc ttgcggttcg attctctaca aaatattttc gtaagtatcg cggacttctt
    15541 gaggccaaac acttgtttgc acttctccga tgtgtctctt gcgaagtagg aacatggcca
    15601 tacgagattg tccaattcct ccaccgattg tcaatgggaa tagaccattc aacaaagact
    15661 tgtgccattc caattccaag cggtcttcat cacctgtaat ttccacctga cgtctaagag
    15721 tttcttcatc tacacgaatt cccatagaag acaactcaaa ggctccacct aaagactcat
    15781 tccagacaag aatatcacca tttagaccct tgtagccatt ctcagactcg cttgtccagt
    15841 catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc tggcaactcg ccaccgatac
    15901 caatcaaaaa gacggctcca aattctttac aaatcgcatt ttcacgttct ttcggtgtca
    15961 agtctgggta gcgttctacc aattcttctg tatggataaa ggtgatttgt tttggcaaga
    16021 tagactcgat gtcatagcgg gcttcaacag ctagctcagt caggcgaata gccttataaa
    16081 tcttctcaac tgtttctttt agataaacga tgttacgctt accatttggg ataaccttct
    16141 cccagtccca ctggtcaaca taaacagagt gggttgcatc caaggaatcc tcatctggac
    16201 gaagggcttt catgtggaca aagagaccct ctccttcacc aaagccaaaa cgagccaagg
    16261 tgtggcgttt ccatttagca agtgagtgca ccacttcata agtagcatca gggatttgga
    16321 gaaccttgac cgatactgga ttttccacac cagacaggtt gtcctgcatt ccgtcaccga
    16381 ccttactcaa gataggacct tgaacttcga caacttctag cttatctttc aaatactggg
    16441 taaaagtgtt tttgacaaag gaaatttctt cttgttgatg gataaaactt ttcttcatag
    16501 acaactcctc aaaaatttaa taaacgtatt atacacctat ttccaagaaa agaaaagaga
    16561 aaatttaaaa aaatcagtgt cactcaaaac actgatttca tagacctttt agtcattgcg
    16621 accaaagata cgtagaatac ttaggaaaag attgataaaa tcaagataga tgctgagagc
    16681 cattgacacc acccaacctg tcgctacacg accttgtgat tgttcatagg cgaggcgaat
    16741 cttttggtta tcccaagcaa tcaaccctga aaaaaccaaa accatggcta cgctaatcat
    16801 ataatcaaag aagccactag ccaagaaaat attgactacc atagcaatca gtaaaccaat
    16861 gagagctgcc atcattgctc gaccaatccc actcaagtct ttcttggtaa agataccaac
    16921 tgccgccatg acaaagaaga gaagggcgct cgatacaaag gcagataaaa ctgtacccgg
    16981 agtatagaaa gccaccacaa aactaagggt aaagccgttt aaaacggagt aaagtaaaaa
    17041 tactggaaga gcagctggac tatttcttga agccatgcta ctggcaacga aaaccaaagc
    17101 caactccgca aaagtagcaa tggtcaacca gagacgcccc tgcatcaaaa agtaaaccaa
    17161 ctgagactga aagaccgtca acataaggcc tgataccaaa gcagatagtc cgattcccag
    17221 accaacaaag gcataaacct tagcgtaaaa ttgattgaga cctgcacggt catgtataat
    17281 agtgtgattc atccatttct ccttttctgt gaacatcttt ccttgattat aacaaaaaaa
    17341 gttaaaatta gcttaaatgg aagattaaaa taccggctgc aaccgcaaca ttcaaactct
    17401 cggcctgccc cttcatgcta atatggacca actggtctgc actttcagcc ataaggggac
    17461 taattccttg accctcattt cccataacta gtacaaaatt ttctatagaa ggcagttctc
    17521 tgtaatcaac agaatcttta gatagggttg ttgctagcac tgggatagct acctttttag
    17581 tttcgtcaag aagcgcttga ctagtcatcc ggtaaatggg cagatggaaa tgactacctt
    17641 gcatggaacg tagggttttg agactgtaga tgtctgccga cttatctgaa acaatcactc
    17701 ctgtaaaacc tgctgcatcc gcagttcgaa tgatagttcc tacattacca ggatcttgca
    17761 catcttccaa aaacaagaac ttgccctgac tcaaatcagc ttgtcctact tcttctcttt
    17821 gaaccacggc aacaattccc tgtggagtct gagaatccgc caaatctagc aaaatatcct
    17881 ctgacaccca gacagtttgc gaaaaagtag ctaactgatc tcgataattt tctagggtaa
    17941 agattttctc aatcgtcact ccagcttgaa cagcttcttc aaacaagtgc cagccttcaa
    18001 tcaaataggc tgacttgcgg tatttttttt ggtgtaattt cttggtattt tttaccacag
    18061 aattggcttt tgaggttata atagtcatag aaatattata acacaatcaa aggggtttgg
    18121 tatgcaaaag gttagaatga ttgcccaagg tagggtacag ggagtcggct ttcgttgggg
    18181 tgtttacagc ttggcccttg aaatcggtgg catcacaggt cgggtatgga ataacgacga
    18241 tggcacagtg gaaatcttag cccaagcaga ctcatctgct atcatggcaa aatttatcca
    18301 agaaatccga aaaggaccga cacctttttc aaaagtaagc tacttagatg tcaaactaag
    18361 caactttcct ccctactctg actttaaaat cgcaaattag gtctccagaa ctattgtata
    18421 ttttgtaaaa aaacagtaga atagaaaggt ataattttta aagaaggaat aaaaacagtg
    18481 aaatctatta aacgttttgc attctcggct atgggagtgg ctatgttgct tgtcttgact
    18541 ggctgtgtca atgtcgataa aaccacaggt cagccaacag gatttatttg gaatacgatc
    18601 ggagcgccta tggctgaagc catcaagtac ttcgctactg ataaaggtct aggctttggt
    18661 gtcgctatca ttatcgtaac cattatcgta cgcttgatta tcttaccact tggtatctac
    18721 caatcatgga aggcaacgct tcactctgaa aagatgaacg ctctcaagca tgtccttgag
    18781 ccacaccaaa cacgtctcaa agaagcaact actcaagaag aaaaactcga agcccaacaa
    18841 gccctctttg ccgctcaaaa agagcacggc atcagcatgt ttggtggtgt aggatgtttc
    18901 cctatcctcc ttcaaatgcc tttcttctct gctatctact ttgctgccca acatactgaa
    18961 ggggttgctc aagcaagcta cctaggcatt cctctaggtt ctccaagtat gattttggtt
    19021 gcctgtgctg gtgtccttta ctatcttcaa tcgctccttt cacttcacgg ggtagaagat
    19081 gaaatgcaaa gagaacaaat caagaaaatg atttacatga gcccactcat gatcgtcgtc
    19141 ttctccctct tctcaccagc cagtgttaca ctttactggg ttgtcggtgg tttcatgatg
    19201 attctccaac agtttatcgt caactatatc gttcgtccaa aacttcgcaa aaaagtccgt
    19261 gaagaactag ccaagaaccc accaaaagca agtgctttct ctaaaccaag tggacgaaaa
    19321 gacgttaccc ctgaacaacc aactgctatc acaagcaaga aaaaacacaa aaatcgcaac
    19381 gctggaaaac aacgttcgag ataagaagaa aaaggcttag ctgatttgct aagtcttttt
    19441 gcaaatcaaa agcccgatgt ttccatcagg cttcttttct atccatgtac acgtttcata
    19501 taatcttgat aactttcggt atccatgagt tttttagcgt tcttgacgcg atctgctgtt
    19561 ggtggtttga ctccttcgag ggaatatgga attccaagtt cacgccactt gaactcaccc
    19621 atggtgtgat aaggtagaat ttcaaactta tcaacatttt tgagggtctt gacgaactta
    19681 ccaagttcaa tcaagtcatc atctctgtct gtcaatcctg gaactagcac gtggcgaatc
    19741 cagacaggtt ttccaatatc tgatagatac tgggcacaag ccaagatatt tttattagtt
    19801 tgtctagtga caatcttgtg ctgttcttcg ttgatttcct tgatatccaa aagaaccaag
    19861 tcagtgacag ccatgagttt gtcaaacttc tcaaggtaac gtggtttatt acggaaagga
    19921 agagcacagg tatccaaggt acagtggatt ccttgttcct tagccttggt gaagagagca
    19981 atcaggaaat caatctgcaa gagagcttct cctccactga ctgtaatccc acccttattt
    20041 ccccagaaac cacggtagcg caaggcctct gtcaagacat catctaccgt ccgttcacgt
    20101 gacttattgg actccatagc ccaagtgtct gggttgtggc aatactggca acgcatgtga
    20161 cagccctgca aaaagacaat aaagcgaata ccaggcccat ctactgaccc aaagctttct
    20221 gtcgaatgca ccattcctgt cacttgtcca taatcaattg tttcttcaga catatcgtta
    20281 ccttccttga aaacgtttta tagttttatt atatcatgac ttgaaggaaa aacaagattt
    20341 ttgcctattt tttagaaagc aatctgtttt tcaatttcat tttcaatcta ttatcagatt
    20401 attcttcaaa atcgaagcca tataaggttg caaaatagtc ctcagggcgc tctgcacggc
    20461 ggatttgacg ggctttacct tcttcggtat agaggatttc cgcagaacgt aatttggcat
    20521 tatactggta gcccattgaa aatccgtggg cacctgtatc atgaatgacc agcaaatcac
    20581 cgatttctgt atgaggcagt tcgcgattga ctgcaaattt atcattgttt tcacagagtg
    20641 aaccaaccac atctaccgct tcagctggtc catctggatg ggtcacgttg ctaatatgat
    20701 ggtaagctcc gtacatagct ggacgcatga ggttgactgc tgaggcatcc acacctagat
    20761 aggtacggta ggtttccttc ttatgagtca ctcttgtgac tagagcaccg tgaggtgcca
    20821 gcataaaacg acccaattcg gtgaaaatct tgacctgacc aagacctgct gacgtaagaa
    20881 cttcttcata caccttacga actccctcac caatcaaggc gatatcgttc ggctcctggt
    20941 ctggacgata attaacacca ataccgccag aaagattgat aaagtctagc gaaatgccca
    21001 acttttcctt gatttcaaca gccagttcaa agagctgacg agccaactct ggataataga
    21061 gatgggtcac ggtattggac gctaggaagg agtgaatccc aaaagtcttg gctccttttt
    21121 ccttcaagat agcaaaggct tcaaagagct ggtccttggt catgccaaac ttagcctccc
    21181 caggattgtc cataatgtct gtccccagtt caaaaacgcc tccaggatta taacgacaag
    21241 agatgatttc tggaatgcct gctactctct ccagatgttc aatatcttca aaggcatcca
    21301 agttaatggt cgcacccaat tcacgtgcat aggcgtattc cttgtctggc gtgttgttgg
    21361 aagagaacat aatctcagaa cccagaaagt ccagtttatg gctcatcaaa agctctacat
    21421 aactagagca gtccacacca caaccttctt cttggagaat tttcaaaata gctggagttg
    21481 gagtagcctt aactgcaaaa tattccttaa agcccttgtt ccacgaaaaa gcttggttga
    21541 cggctcttgc cttctcacga atccccttct catcatacaa gtgaaaggga gtcgggaact
    21601 cggcaacaat cgcttctaac tcttctctat tgataaatgg tgttttcata agcttccttc
    21661 tattctgttt gcaaagaaag gctgggacaa tcgttccaac ctttagttct atctcttatt
    21721 tatcttcgtc aaagatattg ccaacctcaa catcgatggc ttggttcttg acatcaatat
    21781 tagttacctt caagagtgac ttgtagtcaa actgcttttc acgttcttct tgggcattgt
    21841 ccgcaaagac cgctacacct gccagttctg agtcgaactc gcgcaagaga ctaatcatac
    21901 cgttgaccgt tccgccacct ttcaagaagt catccacaat caagacacgg ctgcctgcct
    21961 taagactacg ttttgaaagg aacattttct cgatacggtc accacttgaa cctgaaacat
    22021 agttgacgct aacagttgaa ccttcggtaa ttttcaggtc acggcgcaca atgacaaaag
    22081 agacattgag gacattggca actgcatttg caagtggcac acccttagtt gctacggtca
    22141 taaccgcgtc aattttttgg tccataaagc ttttggcaat aatacgacca atatttttca
    22201 agatggctgg tgtgctaagc aaatcagaca gatagatata accacctggc aagatacggt
    22261 cactttctga caacttggta cgcaagtctt caaccatttc cttagcatcc tgactcgaaa
    22321 tagacggtgt gaagatgaca cctccgccag ccccagtcac tgtctggata tgaccgattt
    22381 caatttcctc aaaggcgcgt ttgataatga cgatatcttc tgagatggat gatttagcag
    22441 actcatactt ttcagcaaaa gtattgagac tagttagttt ataaggatta ttaatcaaat
    22501 agttggaaat gacaaccatc cgatcacttc ttcttaattt catttctatt tcctattcca
    22561 tttttattca aaaaatcaaa aagcaaacta gaaagctggt cgctggtggt tcaaaacact
    22621 gttttgagat tgtcgataga actgacaaac cctgtaatat acctgcatat atacatacga
    22681 caaagcgata ctaccctagt ttgaagatat tttcgaagag tattcatttt tgtcttttac
    22741 ttattatacc atattcacat aaaaaaacga acattcttat cctaaaaaat gctcattttt
    22801 cttaaattat caatctaaat ctggtttata gaaggaacga ttatccatag cgaagatttt
    22861 attggtcatc tctcctttat ccaccaaagc cagagctgtt gacatcatca tcatgcttgc
    22921 atccagattg tcaatcatat ggataatctc tgcctccata atacgtggac ggactggact
    22981 tccatattca agcaagccgt ggtgactgag gatgacatga cgaagcaaaa cgacttcttc
    23041 cttggtatca tcgatgccga gttccataac tgtcttggta atttcgctat caatgagagc
    23101 gatatgtcca agaagattac ctcgcactgt gtactctgtc tggtctggcc ccgtcaactc
    23161 gatgacctta gccaagtcgt gcaacataat ccccgcatag agcagactct tattgagctg
    23221 aggataaact tcgctaatag cgtctgccaa acgtaccatg gtcgccgtat gataagccaa
    23281 ccccgtttca aaggcatggt ggttggtctt ggcagctgga taggagtaga attccttatc
    23341 atacttggtg tagagatttc ggacaatccg ttgccagaca ggattttcaa ttttgaaaat
    23401 catttgcgac atgtagtcac gaatttcctt gacatcaact ggtgacttga ccttgaaatc
    23461 ggctgggtca ttgggttcac cagcttgagg caggcggaga gtaatttgat tgacttgagg
    23521 ggtattgtta taaacttctc ggcgtccttt catgtggaca accttacctg cggtaaaggc
    23581 ctcaatgtta tgaggttggg catcccagag cttcccatca atctcgccac tatcatcttg
    23641 gaaggtaaag gctaggtagt ttttcccagc tcgagtttgc ctcaggtcag ctgatttgat
    23701 taggtaaaag ccttcaaata gctcatcttt tttcatgtga ctaatcttca tattcttcct
    23761 cattttcttg aaaatggagt agatcaagcg caggctcgcc ttctgacaac tcaatgtgac
    23821 ggagcgtccg ctcgatagct atggtacgac ggtttaataa ttcatcaata ttgccagagg
    23881 catgttggag atgtttttgt gccttgacca gaataccacc aaacttgcca aactcggtct
    23941 tgacactggc aagagtcttg ctgatatggt cggcactctt ttggatatta agggtcttga
    24001 aaccaactga tagggagtta agaagggctg atagggtact tggtcctgca acaataatct
    24061 gttcttcccg tctcaaatca tcaaagaaga ccggattgcg gacgatttct gagtagagac
    24121 cttctgtcgg aacaaacaaa actccaaaat tggtcgtccg aggtggtgct atgtacttgt
    24181 tcctaatatc cctagcaaaa cgcttgacac ttgctaggag tgacttacga cagcgttcga
    24241 tttcatcctt gtcacctact tcataggctt cttctaagcg gtaataatct gccagtggaa
    24301 acttagagtc aattggtagg tagacgtatt cttggtcgcc ttgtccgggt aacttgatgg
    24361 catactccac tcgttcacta gagttttcaa ccgttgcgta ttctcgttcg tactgggcag
    24421 gtgtcatgat gtcttcaata atttgcccca gttgcaattc tcccagaatc cctcgcgtct
    24481 tggttccaga gagaaccttg ttaagagctc cgacatcacg ggcaactgtc tgcatttctc
    24541 caagaccacg attgacagac tccagttgtt tagaaactgt ctcaaaggaa gcctgtaagc
    24601 gtgtctgcaa ggtcttttct agtttttcct cgaccgtctg gcgcatttgt tccaaacgtt
    24661 gctcatttga ttcctgcaag gcttggagac gttggtctgt cttgtctcta gtttggagga
    24721 gattatctgt catttcttga cggacttggg tcaggccttg gtgcaattca atccgcactt
    24781 cttgcaaacg gtcgctgaca gccacttcca aatctttttg gtctaactgg ctggcttgtc
    24841 tggcttggtc aaagcggtaa tccaactggt ctgacaaatg atctgcctga tcctccaagc
    24901 tcttacttaa gtgtttctcc tgcctatcct gtctttgcca aatcagaaag agaccagcta
    24961 ggttggcaat taataataga ataagtaaac tttccatcct acctcctgtc cttgctatgc
    25021 agtacgacca cataaccatc tgggcaagtc accgacactt ccctatctat atattcgtta
    25081 gaagcgtaca cttttttaaa gaaaaaattc tcctctgtca actcatactt agctccaaga
    25141 atagtcagct ggctatcccg aactggcata aaggctagat agtcgtagtc tgaacgaggt
    25201 tctagctgac tggtcccttc tgaacaatag gcaatcaaat tttgcccatc ctcaatttct
    25261 atttgacgca tatagggtgc caacttagga ttgctaggta gaaagacatt ggccaacata
    25321 tggtcaatac ggccacccaa ggcaccgaaa atagtgacct cagcctgagg attttgttca
    25381 aagatggtta agagagccaa ttccagatct gtatcatcct tttctggtcg ggcttggaca
    25441 aaatgctggg cacgtttttg aatcacctgt cgctcttctt ccgtcacaga atcaaaatcc
    25501 ccaactgcta gagcaagaag caagtcttct tccaagaccc agagcgagcc tcgatccacc
    25561 ccaacaaaag catcaaaatc tgtccgataa tgaccgcggt ctccgcctgc aaaaacggca
    25621 accctagtcc agttgttttc tgagagtttg tactcgctca ttgacatctc ccttaaagac
    25681 ataggaacct gctacaaaaa cggtcgcacc agcttcttta gcttgggcaa tagtttggtc
    25741 atcaatccca ccatccactt cgatttcaaa gttcaaacct ttttcctcac gaagagcaac
    25801 caactcacga accttatcca tggtttctgg cagaaaggct tgcccaccaa aacctggatt
    25861 aaccgtcatg actaaaactt ggtcaactag atgaaggacg tgcttgatgg cttcaactga
    25921 tgtgccagga ttgataacga ctgaaggctt aactccgagt gaacgaattt tttggagggc
    25981 gccatgaata tgaggcgttg cttctacatg gatactgatg atgtctgcac ctgcacgcgc
    26041 aaaatcttcc agatgatgct cagggtttga caccatcaag tggcaatcga aaaccatctt
    26101 actatgagga cgaaggctct cgaccacacc tgcaccaaaa ctgatttgcg gtacaaaatg
    26161 actgtccatg atatcgatat gggcatattc tgccccagtt gcttctagac gtttgatttc
    26221 acgttcaaag ttggcataat ctgctgccag aattgacgga gcaatcttgt attgagacat
    26281 aggtttctcc ttattttgga atttttttgc tgactttttt ataggtttct ctacgatttt
    26341 caatttcact aaggaattgc aggtaattgt caaaacggaa ggttgcaata acaccctctt
    26401 caacagctgg tttgacggca caagacggct catgggtatg ggtacaagta cggaacttac
    26461 aatctcggct aacagtagca atctctggga aagcctgatt gaggtcttca gcccttgata
    26521 cttcatagtc caaggatgaa aatcctggtg tatctgcgat tttacccccg ttgagattgt
    26581 aaaaactaac agctcgagtg gtatggcgac cgcgacctag actgtctgaa atttctcccg
    26641 tttcaagatt gaggtctggt gcgattttat tgagaagagt tgacttccca acacctgtct
    26701 gccccataaa gaccgtaacc ttgcctgtta acaaagacag gagttcctct ttactggtca
    26761 caaagtcata gccgatgtca ccataggtct gctggtaaaa atccagttct cccctatctt
    26821 ccaacaaatc cattttggaa atatagacaa tgggatggat gcccttgtgc tccaaaagaa
    26881 ccaagaaacg atccagcaaa ttgctgttaa aatcaggttc cttgacggac atgattacta
    26941 cagcttgatc gatattgaca ataggcggac gaaccagact gtttttccgt tcgtgaattt
    27001 tgaggatata gccttctgaa ttttcctcgg cagagaaatc tacccagtcc ccaacataag
    27061 gggtatggcc ttttttacgg aaattcccac gcgcgcgtgt ttgataaacc tggccatcac
    27121 tctccacata gtagaaacct gccaaggctt taatgatttg tccctgcatc ttagagtcct
    27181 tgccctttaa gtgcgtctgc tagaccggca aattctgcca agctgagagc ttccccacgc
    27241 acacttggtg acaagcctgc ctggtccaaa gccttggtca gcttgtcctt gacctcttca
    27301 gtcttaccaa agtaacctgt caagttattc cacaaggtct tgcggcgatg ggtaaaacta
    27361 gccttggaaa ccttaaagaa aaagttctca tcttctactg ctacggctgg ctctggacga
    27421 cgcaccattt tcaagatggc tgaatccaca tttggcgctg gcacaaagac cgtacgaggc
    27481 acgataaagg caaccttggc tgtcatgtaa tactgcacgg cgatagacaa gctaccgtaa
    27541 gccttggtgt taggctgggc tgaaatgcgg tccgctactt ctttctgcat catgaccaca
    27601 aactcactaa aaggaatgcc actctcaatc aagtgcatga gaataggcgt cgtgatgtag
    27661 taaggcaaat tagccactac cttgattggc aggttaggat ttttaaaatt ttggatatgt
    27721 tgcgccaaat caaccttgag aatatcttcg ttaactacag tcacattatc aaaatcacgc
    27781 agggtatcta ccaaaattgg caccaaacgg tggtcaatct caaaagccat gacttgggct
    27841 gcacgctcag ccagaaactc cgtcaaggca ccaatacctg gcccgatttc gatgacattg
    27901 acctggtcat caatttcagc cgtatccaca attttttgaa ggatattggt atccgtcagg
    27961 aaattttgcc cgaaggactt tttaaaggta aaaccgtgac gctccagcac tgccttggtc
    28021 acgctataat ctgcaattct catctattct cttttctatt atctgttact actattgtaa
    28081 cacattcccc ttgtattttg ggaatgaaaa tcataccaaa aaactatctt tcctcatgaa
    28141 gaaagatagt cttggaaatc tttaaaagtg gccttaacag ttctctcgaa acatgcgttc
    28201 atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgtcgtact caagtacagc
    28261 ctgcggctag cttcctagtt tgctctttga ttttcattga gtatcaaaaa aatcagcttc
    28321 ttgataactt ctattttcgg gtagggtcaa atccacatcc tcctccacat catccactgt
    28381 cagttcaacc gtttgaggta aatttttcaa acgataatgc ttttgccttt acccttcaat
    28441 actagcaaaa tcaagcaaat agccatgcac taggatttga accaaaagga gatgattggt
    28501 catattttta tcttctaaac cacctctggc actaggataa tcagataccc tgcgaatacg
    28561 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    28621 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    28681 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    28741 tcaagggtgg atttttcaaa atagtttttg caagggcaac tcgttgggcc tctcccccag
    28801 ataaagtata gattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    28861 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    28921 aattttcttt gattgattgg ttttctaaga ggccgaaatt ttgaaagaga tagcccatct
    28981 ggtctcgaaa atactcacga gtaggaatgg tttttaaatc tttcccctga tagagaaccc
    29041 ttccaccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    29101 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    29161 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    29221 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    29281 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    29341 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    29401 agttcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    29461 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    29521 ccaataagga gagagtaaaa ctccacccgt ttgtcattta gtaccttggc aaaaaatagc
    29581 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    29641 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    29701 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    29761 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    29821 aaagctagcc ttacctgtgg gaggtagtgt ttctgactcg tcacttctac actttcagat
    29881 gaaaagtttt gcaggtaatc tgtaaacaat ccttggtagt agacagactg ctctcgcaag
    29941 ctctcaggca agatcagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    30001 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    30061 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccatctgag
    30121 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    30181 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    30241 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    30301 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    30361 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    30421 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    30481 gtagaaatcc ctgccaaggt caatccataa agtagaagag caatgatgac cagttgcacc
    30541 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    30601 agcactgagc agataagctg tctcacatct tctaacactg gtctgagagc aactccaaac
    30661 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    30721 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    30781 gccgtcaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgataa
    30841 ccaagctctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    30901 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    30961 ggaagctttc cctcaccata agtggcatag gtaaagcgtg tttctccagc ttcatttggc
    31021 tcaacgattc gacgagcaat gagactattg tgctctaccg ccaagtgact caaagcctct
    31081 gtcacctctt cccgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    31141 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    31201 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    31261 cttggtcact tagtgagaag gtgaccaagt aaagctaaac aatagggcta taccattcta
    31321 aacattatag tagaatgcaa ctttctctcc ccaagaagta cgaatccatg cacgagaagt
    31381 ccctccagca ccagcatatc ccttgtcaga tgaaccagtt tttctgctaa caactgttga
    31441 actatggtat tttgaagggt gatagtagtt tgagtaagca ccaccgttac ctgaaccata
    31501 agtccaaaca ccaccttctg ggtattgaac ggctgcagag gcaactgcta cacttccacc
    31561 taatgttgct gcaatgctcg ctacaagagc taatttttta actgtttgtt tcatattgat
    31621 actcctctat ttttgattac aagattgttg agttacttgc tcctctttcc attatcaacg
    31681 ttgatactat tatattacca aatgatattc taaaattatt tgtttttctc taaattgtca
    31741 aaatagcacc ctgaaatgaa cttttatagt cattatactc catctttatc acactatcaa
    31801 ggacatcaat gtccttaaaa tctaactatt tcatattatt tttagcttat atctaaaaaa
    31861 acagttctaa agacgaactt tagaactgtt ttgatacgag gacaaggaca tttttgtcac
    31921 tgattcacta tgtttataaa tattttttga catcctcttg ccattcctct gtcaatttct
    31981 ttactagaaa tccatctcca attagcttcg caaatgtttt agaagactga taaaatgatt
    32041 cagctaaact aaaatctctt tctactctta atgcttgctt ccacaaaaac ataaatacaa
    32101 gaggtttctt ttgataatct tgagttttat ccataatttc ttgtaaacac gatagataat
    32161 cattaaaaca atcagttact cctacctttt caagacaaca cattcctgaa ataagagtat
    32221 ctctaattat aaagtaattc tctatttgag ttaccttctt ctgttccaaa agaaagagca
    32281 ttagcttttc gatttgattt ataaatttgg caagatcttt tctaatgagc atttgataaa
    32341 aaaacaaacg aatcaacaac atatcattta ttgaataagc ttctttttct ataatctgag
    32401 gcatatgttc ctcaagtatt aactctgcat attcaggcct tctagttcta gaagtatcca
    32461 aacacgcctg caatacttca catgctaatt gttcttcttt aggaagatta tcaaagtatg
    32521 ttttataaat ctcttccaaa cacgcttcct tcttatcgta ctcctcttct ttaccataga
    32581 ttggttcacg taaaatctgg tatttcaatt ctaaataagc agaaggaaga gctgaaaaat
    32641 ccggcataag gctataaact ggaactccta gccggcgagc aatataggct aacttgggca
    32701 aactcggttg cgaagctcca ctttcaattc gcgacagttg acgaactgtc agttcttgct
    32761 catctccaca aaaatctgga cgactaattc ctttttctat ccgaatctct ttaatttttt
    32821 gaccaattaa catcagacgc ctcctcttct acctgcttcg aaaaatactg tgaaacttaa
    32881 aaaattgtaa cggctacatc tttcctactc ataagatttc atagcttctt ccacttctgc
    32941 caaagtaacc ccaaacaact ctaggcgttt gaggagttgc ttgccgttag aatagccgat
    33001 tcggagagtc tctccgagat attctctacg cttacggctg tctgcccctg ctagaaaacc
    33061 aaggcgaatc aaatcgctac gactaatgtc aaactgactc tcatgttcaa attgttctgt
    33121 cacctgagct agagccgttt tcaggtcttc atagctggca tgctcaattc ccagagaacg
    33181 ccccttggtc ttggacttgg gaacagcttc atctcgcttg agaaaggcat gctgaactgt
    33241 tggaatggcc gtcataatca tgcgccgaat ccgctcccca ttaaaatctg ggtctgtaaa
    33301 gacaatgact ccatgacgtt ggtgtagacg ctgaatccgc tctatgtcct ggtcattgat
    33361 ggcagaacct cgagtctcat aggtctccac atcgaaataa cgcttgagat tgaccgtatc
    33421 atcacgacct tcaaccacga taacttggga aattctctct ttcattactt gctgtccaat
    33481 ccaaaaatgc gttctgcatt tgcagtcgtt gctaccgcca gctcttctgt cgtcatacca
    33541 cgcaagtcag cgataaagtc gaccacatag cgagtatagg ctgttttatt ttcacgacca
    33601 cgcttgggta caggtgctaa gtaaggcgca tctgtttcta ccaacatctt gtccaaaggt
    33661 aactctttag ctgcttcttg gaggtcagtt gccttcttga aggtcaccac tcctgagaag
    33721 gaaatggtca taccaagatc cacaaacttc tctgcccact caagcgtccc tgaaaatgaa
    33781 tgcatgatac caccacgagg accaacgccc tcactcttga taatctcata ggtatcttcc
    33841 agcgcatcac gggtatggac aacaaaaggc aaatccaagt ccttagatag ccgaatctga
    33901 cggcgaaaaa cctgctcctg cacctctttg ggcgctgtca tccaatggta atctaagcca
    33961 atttcaccta aagccacaac cttgggatgt tttaacttat ccaacaagta agcctcaact
    34021 tcctctgtat aagtaccagc ttctgtagga tgccaaccaa tagtcgcata gagctgctca
    34081 tactcatcta ccaactccaa ggcacgctca atcatcggtt tatcaaaacc aacaatattc
    34141 atctgtatca cacccatctc agcagccaag gcaatttctt ctgcctcacg acctgcaaat
    34201 tcttctacat tcaagtgtgt atgtgtatca aaaatcatct cttctaacct cgttttctat
    34261 cttctattat accaaaaaag aggaggggca cctaattttt cggtttcccc tcctctcttc
    34321 aatagagagc tattctgcta tcttttctat ccgatattgc ccatctccta ttccacagtt
    34381 agagacagaa gagattggct acattgatag aatattccta ttcagctaaa gtatgtgatt
    34441 atcttgggtt ctcacttttc tcacccatca ctaggattga tgacttctca aaatccccct
    34501 tataatctaa ctttaagtag agaatagaat tttctagctg ttctattttc tacgtctagt
    34561 ctttcttcct agcaaagcaa aaccacttgt tgccaccact agaccaagac tagcaagtgc
    34621 tgcacttgat gctgaacctg tgttaggtaa ttgtttgcca gcaggtgact ggtaggtaac
    34681 atcttgcatt gttcctgcag ttgcttgcgg tgcacttgtt gtcttaggag cagcattagg
    34741 agccactagt ctcttaggaa ctgtaaccat ggcaatggct tgcactccaa tcgtttctgc
    34801 ttccttcaca tcttccatag ttttcgcatt ttcaatctct ttgagagctg cttgtttttc
    34861 tgcttccact cttgctaaaa gttctgcttt ttctttatca gaaagcggtg cgcctttgat
    34921 ttcatcctgc ttgtccttgg ctgctttttc aatggcattt ttagctgatt ctttttcagt
    34981 agctaattgc ttagaagctt gtgattgagc tgagttttgt gaacctgtgt gagctgatcc
    35041 acccgcctgg ctaccaccgc cttcattcgc attagcatct gagcttccaa tattgcctcc
    35101 cttatctcca cctggtgtag tttctagctt atactctggt gtaacttctt gagttacaga
    35161 ttcacctttc gcagattgtt gaactgtatc ttttcctaga atcgtcacta ctgaaccatc
    35221 tgggaatgtg attgttgctg taccatctcc agctacattg attgtcgctc cgtctaatgc
    35281 tgaaccattt gcttgtaaaa tagcaacctt aactttttct tcatctgtta aatgagttat
    35341 atcttttaca tctactcttt gagcaggtgc tttaacagtt gatttttcag cagtcggttt
    35401 agtgctatct tgtgcttttg gatcttgtgc taccaattga tttcctggaa ttgtaatagc
    35461 tgaaccatct ttaaagacga ttgttgctgt accatctcca cctacttcaa ctttatagta
    35521 aaataaaata ataacaggac aaatcgatca ggacagtcaa atcgatttct aacaatgttt
    35581 tagaaacaga ggtgtactat tctagtttca atctactata acatcgcttc cgaatccatt
    35641 tgcatctact gaactttttt acaaaaataa aaatcagtag actcgagttc ctactgattt
    35701 ttgatagaat tcgtttggat tatgcagcca aaactttgcg tcctttacga cgacgagctg
    35761 ccaatacgcg acgaccattt ttagttgaca tacggttacg gaatccgtgt ttgcgcgcac
    35821 gacgaagttt acttggttga taagtacgtt tcacgatgaa tacctcctca tagattttgt
    35881 attcgtttag ccggctataa agtgatcagt tactaaacat actttactat tctatctgat
    35941 tctttcactt ttgtcaatag ctctaggcaa atgtttccag ctttttcgaa tgcaagccct
    36001 atctacgata ctgtttcaag aaacgagtca tcttttcttg gatttgggct aactcatcaa
    36061 cacgaggaag gtaaacgata cggaagtggt ctggttcctg ccagttaaag cctcgaccat
    36121 gaaccaagag aaccttttcc tgcttcaaga aatcaaggac aaactgctca tcatcatcga
    36181 tacggtacat attgcggtcg atttttggga agatatagag ccccgccttg ggtttaacgg
    36241 cagacaaacc tggaatatct tgaatggcat tatagatgaa atttctttgc tcgtagattc
    36301 gtccaccagg aagaagtaat tcatcgactg attggtgacc ccccaaggaa gtttgtacga
    36361 cttgttgggc caaaacgtta gagcaaaggc gcatattgga cagcatattg agcccttcga
    36421 tatagccctt aacatgagtc ttagggccag acaagaccat ccaacccaca cggaaacctg
    36481 ctatgcggtg ggattttgac agaccattca tgctgacaca gaagacatct ggtgccaagc
    36541 tcgccacagg cgtatgcaca tgtccgtcca ttaccatgcg gtcatagatt tcatccgcaa
    36601 agataatcaa atcgttttga cgggcaatct caataatctc cagcaagagt tccttaggat
    36661 aaagggctcc agttgggtta tttggattga taaggacgat tgccttggta ttggaagtga
    36721 tttttgactt gatatcgtca atatctgggt accattcaac agcttcatca cagatatagt
    36781 gaacggcatt tcctccagct aggctgacag ccgccgtcca tagaggatag tctggcattg
    36841 gcactaagac ctcatcccca ttgtccaaaa gcccctgcat ggacatgaca atcaactcac
    36901 tgacaccatt tccaaggtaa atatcatcaa tatctacgtt tgggaatttc ttcatctggc
    36961 aatactgcat gatggcctta cgggctgaga aaatcccttt ggagtcagaa tagccttcac
    37021 tatcacgcgc attcataatc aagtcatgaa tgacctcgtc tggcgctgta aagccaaatt
    37081 ctgctggatt tcctgtattc agacgtaaaa tcttttctcc attcgctcgc atccgcatgg
    37141 cttcttccaa tacaggacca cggatatcat aagcaacatg ctctaactta ctagacttgt
    37201 tatattcttt catcttgttt cctcaattca tcaggatagt aacattatac cactagaaag
    37261 agaatgcgac aagtttactg aaatgtgtta ctagtttcgt atagaagaaa aaccttgcta
    37321 aaggcgaggt taagaacgta gagatagcag gtattttgca aagacacatc acataccaaa
    37381 agataaacct agaaaaagca agcctagaaa ggagtcataa agaagattaa acatgaggaa
    37441 aagcccccat atcatcaagt aatcccaacg cccacttcgt tttgcaacta gaaataagat
    37501 tagatggtag agtacatgaa agactaaaaa tccaataaaa cttggataaa gaagcggtac
    37561 cagactctct aattgacaga tcatgatcac ttttaccaag actgaaacta ggataattcc
    37621 ataataaagg aaatttgatt tttgaaaaga gtttttcatc attctccttt cctcctatcc
    37681 tttcttttat tttatcatat atttatatag agtttaagcc ctaatattct tttgaaaaat
    37741 actttttttg ctttacttct atagtgaaaa ggtttacaat tatagtaaga aaatttcagg
    37801 aggtttcatt atggcacaac gttaccaaaa tatcatggtc gcaatcgatg gttctaagga
    37861 agcggacttg gcttttgtca agggagttca ttctgctcta cgaaacgacg ctaaactcac
    37921 catcgcacat gtcattgaca cacgcgctct ccaaagcgta tccacctttg atgctgaagt
    37981 ttacgaagaa ctccaagtcg acgctgaaag tctgatgaaa gagtacgaaa aacgtgctaa
    38041 agatgctggg gtagcagatg ttcatatcgt cattgaaatg ggaaatccaa agaccctgct
    38101 agcacgtact attccagatg ccgaggaagt ggacctcatc ctcgtgggcg caactggtct
    38161 caacgccttt gaacgcctct tggtcggctc ttcatctgaa tacatactcc gccatgctaa
    38221 ggtcgatttg ctggttgtga gagaacaaga aaaaacctta taatcacaaa gaaaaggagc
    38281 ccctagctcc tttttgttta cgatttattt ctctctttat ggcgttcgta agccttgagc
    38341 tggcgatgca gttccttttt aatagcaggt tctggagcat atttttcttc ccaattatct
    38401 ggttttaaga ttttatgggt cactggatca aaatgagcct tgccatctgg aaaaattttc
    38461 cccatattgg cctgatggac aatatcaaaa atacgttctg ggtccacccc catcaagaca
    38521 aaactgccgt aggtgaagta aagcgtgtca atcaaggcat ccacttgccc tatcaaatct
    38581 tgctgagcag gtgtcttctt ggctacttta cctgctgcct tatcaagggc ctgatgaagt
    38641 tgcgatacag cttgaccaaa atcttcttca gaaggactgg ctgctcgaac aaactccacc
    38701 aattcttcta ttttaaaacc agccctatgg gttgcaccct ctaaatccca agctcgaggt
    38761 tcttcttggg ttcgttcatc catcatgtgg tggaaggtct tgaccttatt gaaatgatag
    38821 tcacggctga caaagacttt ttctgaagac aaaacaccaa aatgttccaa ggccttgtgg
    38881 atcccatctt gttgattgct agtggtaatg tgcttggcag cttccttgac actgctacta
    38941 ccatttccca tagcgaccga cataccgacg ccagccagca tttcaaggtc attatctgag
    39001 tcaccaaaag ccatgacttg gttgaggtca aagccatatt ctttcccaac tcggcgaatg
    39061 ccttctaatt tagaatttcc ctgattgatg acatccgatg caaaaggatt gctacgtgtc
    39121 aatttcaagt cttcaaaatc agctgccgcc ttctcagatt cttctggtgt catcagcatc
    39181 aaaacttggt agataggctg attcatcagg tgaagcaggt cctcttcctt ttggggaaca
    39241 accttgctga ccatgcgatt aaaagactga ctcaccgtcc gagttaaaac agagggaacg
    39301 aagcgactaa ttcgttggga aaaagaaccc agaccaaagg acatgatttt agaacccaac
    39361 atggcatcct tggtccctag agcaatctcc gtgccctctt ttttagcata gctaattaga
    39421 tggcgcaaat gtaacttgga aatagggctc gtgaacaaga ctctgtcttt actaaagata
    39481 tactggccat tataggttac cgcaaaatcc agatccaaat cgtccatcaa ttccttaaca
    39541 aaaaaaggtc ctcgccctgt cgctacgcca actagtaccc cttgttcttt gacaatctta
    39601 atcgcgtcct tagtggattt caaaacactc ttgcgattgt tgaccaaggt tccatcgata
    39661 tcaaaaaaaa cagctttgac ttccatccta ttccaatctc cccttttgtg atacaatgat
    39721 tataccacat ttcagaaaga gtgagtaaat catgcctaag aaaatccttg ttttacatac
    39781 gggtggaact atttccatgc aggccgatgc ttctggcgct gttgtgacga gttcagataa
    39841 tcccatgaac catgtgtcca acccacttga aggaatccaa gtccacgcct tggacttttt
    39901 taaccttcca agtccccata tcaaacccaa acatatgctg gtcctctacc agaaaattaa
    39961 agaggaagca gataactacg atggagtggt gatcacacac ggaaccgata ctttagagga
    40021 aacagcctat ttccttgata ccatggaagt tccccatatg cctatcgttc taacaggagc
    40081 catgcgtagc tccaatgagc tcggtagtga tggtgtttat aattacctaa gtgctttacg
    40141 agtggccagc gatgacaggg ctgctgacaa aggagttttg gtcgttatga acgatgaaat
    40201 ccacgctgcc aagtatgtca ccaaaacaca tacgactaat gtcagcacct tccagactcc
    40261 aacacatggc cccctcggtc tcaccatgaa acaggaaatc ctctacttca aaacagctga
    40321 acctcgtgtt cgctttgacc ttgatcacat acaaggttta gtccctatca tctcggctta
    40381 tgctggtatg acagatgagc tgattgatat gctggattta gaacacttgg acggtttgat
    40441 tatccaagcc ttcggagctg gtaatattcc caaagaaacg gctcaaaaat tagaaagcct
    40501 tctgcaaaaa ggaattccag tcgctctggt atcacgatgc tttaacggta ttgccgagcc
    40561 tgtttatgcc taccagggtg ggggcgtaca gttgcaaaaa gcaggcgttt tctttgttaa
    40621 agaactcaac gcccaaaaag ctcgcttgaa actcctcatc gccctcaatg ccggactaac
    40681 aggacaggct ttgaaagact atatggaagg ctaatactct tcgaaaatct ctgcaaacca
    40741 cgtcagcgtc gccttaccgt atgtatggtt actgacttcg tcagttctat ctacaacctc
    40801 aaaaacatgt tttgagctga cttcgtcagt tctatctaca acctcaaaac agtgtgttgc
    40861 gcagccttta accagccgcc tagtccgctc tatggtattc attaagtcaa catctcttgt
    40921 ttaagagcac aaaatcagga aatcttctcg attccctgat tttttctatt tacgttttcg
    40981 tgttgagcta cgttctgtca aaccatgagg taagagaact tcacgttctt ccaactcttc
    41041 cttatgcata atcttggtca acatacgcat actaatggca ccaaggtcat aaagaggttg
    41101 ggcaatcgtt gtcaagtttg gacgggtaaa gcgtgagatt tgtgaatcat cactagtaat
    41161 aatttcaaaa tcttctggca cagaaacacc cttatcagcc aaaccgttca agactcctgc
    41221 tgccaactca tcacctgtca caactgctgc agttgcattt gatgaaatca aacgctctgc
    41281 taaggcgtaa ccatcatcat agctatattt agattcaaat accaaaccct cactataagt
    41341 gattcctgct tttttcaagg tttccttgta gccaactaaa cgaaccttac cattgatgtc
    41401 atccactagc ggaccgctaa cgaaagcaat acgctcattt tctttagcaa ggtaactcac
    41461 tgcatcaatt gttgcttgct tatagtcaat attgacactt ggcaactggt gctcaacatc
    41521 gacagttcct gcgagaacaa tcggagtacg tgaacgcgaa aattctgagc gaattttatc
    41581 tgtcaagtga taacccatat agataatgcc atctacctgc tttgaaaaga gggtattgac
    41641 aacagaaact tctttctcgt tatcttcatc gctattagct aggacaatat tgtacttgta
    41701 catttctgca atatcatcaa tccccttagc caaactcgaa aaataaccat tggtaatatt
    41761 tggaatcacg acaccgacag tggttgtctt tttacttgca agaccacgcg caactgcatt
    41821 tggacgataa tccaaacgat caattacctc tagcactttt ttacgggtat tctcttttac
    41881 atttttattg ccattgacca cacggctgac cgtcgccatg gaaacacctg cttcacgagc
    41941 gacatcataa atggttactg tatcatctgc attcattcct tttcctgtcc tttctatctc
    42001 acacattctt ttacaagtag aggtactgat tgaagctcta tatctactta caaaagtgaa
    42061 gatgtgaaaa tttcgttttc atatttctac ttattccatt ctatcactaa ttgtaaacac
    42121 tttcaagtgt tttttgaaga ttgattgaaa aaatttcata gaaaacctag gtttagctcc
    42181 ttgctaccac cttagactaa acaaaaagga ggaaactaag ccctcctaaa gttatagtaa
    42241 aatgaaataa gaacaggata aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
    42301 agaagtagag gtgtactatt ctagtttcca tctactatag gtattgttcc attcactacc
    42361 gtcaatttta gcacatagtc ttcatgaaaa tattatatca tcataaccaa ccagattctt
    42421 ttgcgatatt agctgcctct gttcgattac cagcatccag ttttgaaaga atattggtga
    42481 catagtttcg aatagttccg tttgagaggt aaagctgatc tgcgatttct tggttggata
    42541 agccccgggc gattcccttt aagacagcaa tctcttgttc tgtcaacgga ttgggacggg
    42601 tcatcaccac ttccatcaat tcaggcgaat actccttgcg tccttcgagg acggtgtgca
    42661 aggtttgcat gaggtctgca atgcttcgtt cctttaatac ataagcatcc actccagcct
    42721 tgaccgcacg ttcaaaatac ccagcacgct tgaaggtcgt caccacagcc acctttgttt
    42781 caagcctttc tgatcgtatc cactccaaga cttcaagacc tgtcttaaca ggcatttcta
    42841 cgtcaaggat ggcgatatct acagactcct tttctaatag ttggattgct tcttgcccat
    42901 tcttggcttg aaggacagac tccacatctg gttgaagcgt gagcaattga cacatggcat
    42961 ctcgcaacat actttgatct tctgcgacta atactttcat cttagtttct ctccttataa
    43021 ggtagtcgaa cttgcacttc cgttggatgt ttctgactga ttacacttac ttctcctgaa
    43081 aatggaaaaa cacgatctcg gactgtatgg agctcatctc cttttagaaa agcaaagccg
    43141 cagccatcat cacttactgt taaaatgagt tccttctctg tccgttctaa ttttaagtaa
    43201 gctttagacg ctttggcatg tttgatgata ttggtcacca actcaagcaa aatcatagaa
    43261 gccattgaat ccaattcttg agtaaggcta gcagtatcta gttggttatc tgtttccacc
    43321 tcaattccag caatttctaa catctttttc acagtctcta gttcggatgt caaagttcta
    43381 gacttaagat tttccacaat ggttcgaact tcacacattg attctttgct aatttgctgt
    43441 atttctctta attccttttc cacttgtgga taagcctgca tttgaaatag ctgcaaggct
    43501 agatctgtct tgacactaag catagcaaag gtatgtccca gactatcatg caaatcctga
    43561 ccgatacgat tgcgctcatt ttctgctagc aatagattta tctgggtatt ttgcttgacc
    43621 tgagcttctt tcaaatcctc gacaaggcga attcgaaccg agcccaaagt catcaaatcg
    43681 acaaaagtaa gaattacaag catatagact agaaactcaa cttcgattct ctgaaaaatc
    43741 aaaagtcgcc ccacaacaag gacttgagca aggagaaatg tccatacatg taaagacttt
    43801 aaactacgta cgccaaaatg ataaattaag agattggaaa ggaaaaagaa aaaccagata
    43861 taattcccag caacaaaggc ggtattccca gctacataga ccagcatgag cccccagaaa
    43921 agccaagata ggcgctggtt cttagttatt aaaacaccca aatacgtcac tacaaataga
    43981 atatcaacca ataaatgcca agcaggaagc tccccaatca ctacaggtag gatgggaaaa
    44041 agcataaaaa tcaaactggt ccaaaacata tagtgtatgc ttttcagtct ttcaagcatt
    44101 aagcattctc cttatgacct tgaaggtaaa tagtcaaacc aaataaaact gctgaaaaaa
    44161 caagtaaata aactgtggct gatagattga tgtcaccctc gtttaagaag gtcttgagca
    44221 actccatcaa ttgataggtc gggagacact taccaactgc ttgcatccag tctggaaata
    44281 aagaaatggg catccagagt ccgcctaaaa cagccaatcc tagataaaga agattgccca
    44341 caacagacat cagctgacta gttggtaaga gagtcaaggt caagccaagt gctacaaaag
    44401 caatactccc cacaatcagc aaaatcgcag ctccaaccca ttttactaga ggcatgtcta
    44461 cacctcttac aaaatgtcca actgtaaaaa caaccagaat tgagaccaaa taatcaacca
    44521 gcatacttgt tatctttgat agataatatt ctaccatatt tacagggcta tgacgcaatg
    44581 ttttctgcca gttgttcatc ttatcggtat gtaaaacagc tggaaatgag aggatagttg
    44641 tcgacatcat ggaaaaggca gtcatggaga tgaggtaatc acgcataaaa ttcgcgagtt
    44701 cacctggtgt gtcctgatag ataccagaaa aaaataaata gaaagccgtc ggcatcccta
    44761 ccgacaatag ataatagatt aattgtcgtt tggtcaataa aaattctatc ttactaagtg
    44821 ctatccatcg tttcatctta gttatctccc ttctgcgtct cttcaaagat tgtattcaac
    44881 aaactacgat tattaacttc gatttcttgc atcctacatc ctgcttgggc taatagttcc
    44941 cagaaagcat ctgcttctcg agtgactact tgtaaagaat cttgctttag ggtccagttt
    45001 tcaaccaaat ttgactgctc tacgacttcc ttgtaagcta taggaaggat aaagtgcttt
    45061 tctatttcct cgctacgcat agctagaggc gtcgtatctc gaatcaactc tcccttattt
    45121 aagagcaaaa tgcggtctgc agtgtgttcc acttcctcaa tataatggga cgaatagaga
    45181 atggtaactc cctgcgcttt tagatcctga acaatttccc aaaaacgttg gcgggttgag
    45241 gtatccatgg ccgcagttgg ctcatctaaa aagacaagtt ttggtcggcc aatcaaggtc
    45301 aagacaaaag agaaaagacg cttttgccca cctgacaatt tttctgccaa ttgctctttc
    45361 tgttgcttgt caaactgcaa cagttgatcg atttcctggt tgctcaaggg atttggataa
    45421 atgctttgaa agaaagcaac caactctttg acctttaatt tctgaacgat gacattttct
    45481 tgaggcagat aacctctaat atagtctaac tgagaactcg tcactgacaa gccttggatg
    45541 gatacttgac cgcttgtgac cagtttatct ccaagcagac agtccaagag tgtggtcttc
    45601 ccagcaccat ttggcccaat caaggcgacg cattcacctt cagctacctc aaaggaaata
    45661 tccttcaaaa tagcctttcc cttgatgttt ttatgtaatc cttgaacctt aatcatgtcc
    45721 atgatattct cctttcaacc actccattcc cataggaaag gcgataaaaa tcataaatcc
    45781 tagtccccag gcaccacgga tgaattggcg aagcaaggct tgatcaaacc aacctgtaaa
    45841 catttctacc aaccatacca ctagtgatag tccaataaaa agatagagaa acgctttttt
    45901 catttttcaa actccttttt cacatctgag actaatttca aaccttctcg gataagccag
    45961 gacatcattc caaatcctgc aaatagctcc caaggaaaat gatagaaatc ttcatccaat
    46021 cctgagaaca tgagataagt catgactcct gctgctacta aactcattgc gacaatcatt
    46081 ttatttttca tctcttcttc ctccgtttca tacttcaatt atagactttt gaagttggcg
    46141 gagctagatg cttctgtcac tagaaaatat gacaaatgtc ataaaaattc tgtacaaaac
    46201 aagcaagata cactatataa taaaacacaa gtagaaaaaa tctaaggcag ctttcaaaag
    46261 agatatcaaa cccaattcac accataatgt aaactaatac ttatttaaaa tcaaaaagag
    46321 cggaaatttt tatcgcacaa acacatatat tataagcaga gcgaaaaact cttcaattac
    46381 tttcttaaaa gtttgtaaga attatacaat ctgttaaatt ttaatttatg tacctaaact
    46441 acagtattca ttgaacaaat taggaaacaa aaaagtatac gctgctaaaa tgaattactg
    46501 aaattcaaaa aagagagaag caaactgatt ctctcttaat gtatataata tctagttaaa
    46561 acaaaaagat acgcttacgt atctctgaaa
//
LOCUS       DAVIME010000011        44658 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVIME010000011 DAVIME010000000
VERSION     DAVIME010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.011"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(310..2037)
                     /gene="ezrA"
                     /locus_tag="VV588_000658"
     CDS             complement(310..2037)
                     /gene="ezrA"
                     /locus_tag="VV588_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU7083035.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAESYNHSF
                     CFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2119..4065)
                     /gene="gyrB"
                     /locus_tag="VV588_000659"
     CDS             complement(2119..4065)
                     /gene="gyrB"
                     /locus_tag="VV588_000659"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU7083036.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4080..4643)
                     /locus_tag="VV588_000660"
     CDS             complement(4080..4643)
                     /locus_tag="VV588_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU7083037.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTSFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4728..5282)
                     /locus_tag="VV588_000661"
     CDS             complement(4728..5282)
                     /locus_tag="VV588_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU7083038.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5293..6516)
                     /locus_tag="VV588_000662"
     CDS             complement(5293..6516)
                     /locus_tag="VV588_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU7083039.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPRLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPIFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6553..9003)
                     /locus_tag="VV588_000663"
     CDS             complement(6553..9003)
                     /locus_tag="VV588_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU7083040.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSCRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVVSLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9203..10132)
                     /locus_tag="VV588_000664"
     CDS             complement(9203..10132)
                     /locus_tag="VV588_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU7083041.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10272..10559
                     /locus_tag="VV588_000665"
     CDS             10272..10559
                     /locus_tag="VV588_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU7083042.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10593..11927)
                     /gene="ciaH"
                     /locus_tag="VV588_000666"
     CDS             complement(10593..11927)
                     /gene="ciaH"
                     /locus_tag="VV588_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU7083043.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(11917..12591)
                     /gene="ciaR"
                     /locus_tag="VV588_000667"
     CDS             complement(11917..12591)
                     /gene="ciaR"
                     /locus_tag="VV588_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU7083044.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12700..15246)
                     /locus_tag="VV588_000668"
     CDS             complement(12700..15246)
                     /locus_tag="VV588_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU7083045.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15369..15809)
                     /locus_tag="VV588_000669"
     CDS             complement(15369..15809)
                     /locus_tag="VV588_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU7083046.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15784..16653)
                     /locus_tag="VV588_000670"
     CDS             complement(15784..16653)
                     /locus_tag="VV588_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU7083047.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16631..17131)
                     /locus_tag="VV588_000671"
     CDS             complement(16631..17131)
                     /locus_tag="VV588_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU7083048.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17142..17840)
                     /locus_tag="VV588_000672"
     CDS             complement(17142..17840)
                     /locus_tag="VV588_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU7083049.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17833..18069)
                     /locus_tag="VV588_000673"
     CDS             complement(17833..18069)
                     /locus_tag="VV588_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU7083050.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18169..19095)
                     /locus_tag="VV588_000674"
     CDS             complement(18169..19095)
                     /locus_tag="VV588_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU7083051.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19170..19985)
                     /locus_tag="VV588_000675"
     CDS             complement(19170..19985)
                     /locus_tag="VV588_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083052.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(19989..20309)
                     /locus_tag="VV588_000676"
     CDS             complement(19989..20309)
                     /locus_tag="VV588_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU7083053.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20471..20551)
                     /locus_tag="VV588_000677"
                     /pseudo
     CDS             complement(20471..20551)
                     /locus_tag="VV588_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20595..22592)
                     /gene="metG"
                     /locus_tag="VV588_000678"
     CDS             complement(20595..22592)
                     /gene="metG"
                     /locus_tag="VV588_000678"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU7083054.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22716..23975)
                     /locus_tag="VV588_000679"
     CDS             complement(22716..23975)
                     /locus_tag="VV588_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083055.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(23977..24678)
                     /locus_tag="VV588_000680"
     CDS             complement(23977..24678)
                     /locus_tag="VV588_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083056.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24662..25861)
                     /locus_tag="VV588_000681"
     CDS             complement(24662..25861)
                     /locus_tag="VV588_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU7083057.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26147..27493
                     /gene="gor"
                     /locus_tag="VV588_000682"
     CDS             26147..27493
                     /gene="gor"
                     /locus_tag="VV588_000682"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU7083058.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            27690..28226
                     /locus_tag="VV588_000683"
     CDS             27690..28226
                     /locus_tag="VV588_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU7083059.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(28427..28642)
                     /locus_tag="VV588_000684"
     CDS             complement(28427..28642)
                     /locus_tag="VV588_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU7083060.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28740..29060
                     /locus_tag="VV588_000685"
     CDS             28740..29060
                     /locus_tag="VV588_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083061.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29091..29429)
                     /locus_tag="VV588_000686"
     CDS             complement(29091..29429)
                     /locus_tag="VV588_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083062.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29441..30160)
                     /gene="trmD"
                     /locus_tag="VV588_000687"
     CDS             complement(29441..30160)
                     /gene="trmD"
                     /locus_tag="VV588_000687"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU7083063.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30150..30668)
                     /gene="rimM"
                     /locus_tag="VV588_000688"
     CDS             complement(30150..30668)
                     /gene="rimM"
                     /locus_tag="VV588_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU7083064.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELTLFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30698..31486)
                     /locus_tag="VV588_000689"
     CDS             complement(30698..31486)
                     /locus_tag="VV588_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU7083065.1"
                     /translation="MKRFEVSTEIGSLSVTYKKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32063..32302)
                     /locus_tag="VV588_000690"
     CDS             complement(32063..32302)
                     /locus_tag="VV588_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU7083066.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32322..32594)
                     /gene="rpsP"
                     /locus_tag="VV588_000691"
     CDS             complement(32322..32594)
                     /gene="rpsP"
                     /locus_tag="VV588_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU7083067.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            32764..32973
                     /locus_tag="VV588_000692"
     CDS             32764..32973
                     /locus_tag="VV588_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083068.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            33455..33667
                     /locus_tag="VV588_000693"
     CDS             33455..33667
                     /locus_tag="VV588_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083069.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            33751..34554
                     /locus_tag="VV588_000694"
     CDS             33751..34554
                     /locus_tag="VV588_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU7083070.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGNGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34610..36151)
                     /locus_tag="VV588_000695"
     CDS             complement(34610..36151)
                     /locus_tag="VV588_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU7083071.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36153..36635)
                     /locus_tag="VV588_000696"
     CDS             complement(36153..36635)
                     /locus_tag="VV588_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU7083072.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(36635..37720)
                     /gene="rlmN"
                     /locus_tag="VV588_000697"
     CDS             complement(36635..37720)
                     /gene="rlmN"
                     /locus_tag="VV588_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU7083073.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMTIGARHITVSTLGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDSVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(37741..38271)
                     /locus_tag="VV588_000698"
     CDS             complement(37741..38271)
                     /locus_tag="VV588_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU7083074.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(38427..39032)
                     /locus_tag="VV588_000699"
     CDS             complement(38427..39032)
                     /locus_tag="VV588_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU7083075.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39205..40242)
                     /locus_tag="VV588_000700"
     CDS             complement(39205..40242)
                     /locus_tag="VV588_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU7083076.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40276..41211)
                     /locus_tag="VV588_000701"
     CDS             complement(40276..41211)
                     /locus_tag="VV588_000701"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU7083077.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(41764..42954)
                     /locus_tag="VV588_000702"
     CDS             complement(41764..42954)
                     /locus_tag="VV588_000702"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU7083078.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43169..44512)
                     /locus_tag="VV588_000703"
     CDS             complement(43169..44512)
                     /locus_tag="VV588_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU7083079.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
BASE COUNT        13220 a         9774 c         8070 g        13594 t
ORIGIN      
        1 ttattggacg gttaccaagt tactcaaagt acagatttga agctgcagat aagactgacg
       61 aaatcacttt aatactaaat gaaaatcaaa aagcaaacta agaagctagc ctcaggctgt
      121 acttgagtac ggtaaggcga cgctgacgtg atttgaagag attttcgaag agtataaaac
      181 actgttttga ggtggtggat aaatcggctg ggtaaaaact caatctcagg agaaaatgaa
      241 gtaaatctcc ccgcaactat agaaaaagat ttgattctgc tcctcacaca ataaaatctt
      301 tttcttttat taaaaacgaa tcgtttcacg tgttttctca tatgaggtaa caaagcgatt
      361 agttacacca ggctctgcca cttccaatgc ttgagaaatc ttgtcaaatg aagcgtgata
      421 atcaaattct ttttcaaaaa tatctaaagc ttcgttaaat gcttcttgaa tgcgttcatc
      481 aaatgagcga tagcggttag aatattgcaa gagttgctct gtcaaagttg catattgtac
      541 aatattataa gtttccgttt ctaaagcttc catatcattc gttgcaattt caagaactcg
      601 ggtaacagat tcaatgttaa tcattttttg ttctaactca accattaaat cctcggtatt
      661 attgcttgcc gtaaagaata acttcaagaa agtttgtgga atacctggca gattgcgttt
      721 ttccatgtat cgcttgatag tatggagacg attgacataa acattggcct tttgacgtgc
      781 attaatatca tctttctcaa tttgtgtcag gcgctcacta actgaaattt gctcatcttc
      841 aatatctttt agttgagttt gtaaatcctc aagattttct tcaagaactg aataagcttg
      901 ggttggttct tcttgattcg aagttacctc aacaatagct gcctcaaaac tctctaattc
      961 tgtctgaata cgacgaacat ggcttgcagc tgtctcagga agtaaatagg tcttgttcaa
     1021 acgtgcaata tcttctccca ataaagtatt attctctttc atatgttgaa ggtaagttgg
     1081 aagagttgca agtagatttt ccactacttt ctgagcagca atttctcgag taaaaatatc
     1141 atacaaggca ttgatttcct cttgtgcctg tccattctca tattcggcat tatccaattc
     1201 caactgacga atattctctt ggtttttctt gaatgcttca taaagcaagt ggaaacgcgc
     1261 ttcaatatcc gtttcaacaa aatgataatt agcatcaatt agtttacgat aaccggcttc
     1321 caaatcctgt aattgatctg gcaattctgt agaaagcgtc gtaaccaagg ctggaacacg
     1381 atccacaata tgacttaagg ccaaaatgtg attttctgta ttatccaaaa tcactgcggc
     1441 ttccacaggg tcacccgatg aattcaaggt tacaaattgt gaaaattcag attggatatt
     1501 ttctaattgt ttttcaattt catccaaggc ttgaccatac tgttctgaat tttcagcaac
     1561 tctatgctga agttcctcaa ataaatccaa agcatgaaga acacgaccac tatttttaga
     1621 ttcttgcttc tctaagtctg ccaaagcatt gcgaattgcc gcaatatctt cttcaatcaa
     1681 agtaatttga ctctcaattt ggtcaatttg atgactggcc ttgagaaaac aaaatgaatg
     1741 gttatagctc tctgcttcaa agagattatt ttcaatatcg gcaaaagagt tgagagataa
     1801 atcgacccat ttttgattcc attcacggaa agccacttga ctttgtccaa tcaagtgcat
     1861 attttttaca gcttctactt catcatttac tggaagattg tatagttctt cttttctttc
     1921 ttctagtgcc tctaatctcc cctcgtttcg cttacgtaga aagattgcca ctacataagc
     1981 cagaactaaa atgactgcaa ttgcaaccat taaataaatt agttgtccat tagacatatc
     2041 aaactccttt tttacttgaa acaatcgtaa cgattatatc atatttttta gaccaaggga
     2101 actacttctc cctatttttt agacatcaag tgtactatag acagcatttt cttcgataaa
     2161 ctcacgacga ggctctactc gatcccccat caacatatca aagattttat ctgcttctgc
     2221 agcatcatct acagaaactc tagccatcaa gcgatgttcg ggatccatgg ttgtttccca
     2281 cagctgatga tcgtccattt cacctagccc cttataacgc tgaatagtcg gtttggtacg
     2341 accttcacta taacgggcta aagcttcttg gagtttgatt tcttgatctg cacccggctg
     2401 gatatattct ttaatctcgc ttccaacctt gacaccatag attggtggtt gggcaatata
     2461 aacataacca gcttctagga ttggtttcat ataacgataa atcaaggtta aaagaagggt
     2521 acgaatgtgg gctccatcga catcggcatc ggtcatcaaa acgagttttt ggtaacgggc
     2581 tttcgaaaca tcaaattctg cgccaaatcc tgttcccatg gctgtgaaaa gactacgaat
     2641 ttcttcgtta gctagaatct tatccatact tgctttttca acgttcaaaa tcttaccgcg
     2701 aattggaagg atagcctgaa actcacggtt acgaccagat ttggctgatc caccagctga
     2761 gtctccttcg acgatgaaga gttctgtttc agcagggtta ttagaagaac agtctgctag
     2821 tttccctgga aggttggaaa tttccaaacc agatttttta cgtgtgactt cacgcgcacg
     2881 cttggcagcc acacgagcct tggcagccaa aattcctttt tctacgatac gtttggcaat
     2941 ctgtggattt tccatgagga aatcggagaa ggcttcactg aagaggcgat tggtaatctt
     3001 gaccacttcg ctatttccca atttggtctt ggtttgtcct tcaaactgtg gatttgggtg
     3061 tttaactgag ataactgcag ttaagccttc gcgaacatct tcccctgtta ggttgtcttc
     3121 attgtctttc agtaacttat ttttacgagc ataatcattg ataacacgtg tcaaggctgt
     3181 acggaaacct tgttcatgcg ttccaccttc atgtgtatga atattattgg cgaaactcat
     3241 gacattttca tggtaaccag ttgtgtactg catggctacc tcaactgtga tatcatccat
     3301 ctcaccgtct gtatagattg gtgtatcaaa gattacatcc ttgttctcgt tgatatattc
     3361 aacgtaacta gcaatcccac cttcataatg ataatgcttg gtttgttcca aaccttggcg
     3421 cttatcagtg atagaaattt gaagaccgcg atttagaaag gccaactctt gaatccgttt
     3481 atttaattta tcaaaatcaa agattgttgt ttcagtgaaa atttctgggt ccggtgtgaa
     3541 gtgaaccgtt gttccagttc tatctgtatc cccaaccacc tcaaggtctg caacaacatg
     3601 accacgacgg tattcttggt aatgaatctt accgttttta tggacatgaa cgtctaattg
     3661 agtggaaagg gcattaacta ctgacgaccc caccccgtga agaccacctg aaaccttgta
     3721 tccaccaccg ccgaactttc ctccagcatg aaggactgta aagacggtct caacagcagg
     3781 acggcctgtt ttttcctgaa tatcgactgg gataccacgc ccatcatcca caacagtaat
     3841 cgaatcatct ggctcaataa aaacttgaat atggctggca aatcctgcca aggcctcgtc
     3901 aattgagtta tcaacaattt cccagactag atggtgaaga ccttcttttg aggttgatcc
     3961 aatgtacatc cctggacgca tacgaacagc ctctaagccc tctaaaactt gaatttgact
     4021 ggcatcataa tcctgtgcct gcagattttt gatttcttct gtcatcttat tcctttttct
     4081 tatatgtcta atacttgtct taaattcacg atactggtaa acaagtgggt atcaagtcct
     4141 gcagcttgac ctgcttcgat atcaatcggc cgatcaccaa tgacaagacc agagctaatc
     4201 tgatactttt ctcttaaata aagcatggat tcgggatttg gctttctctt aaagcctgag
     4261 ctagaagtca ccacttctgt aaaataagct gctatagagg ttttttctaa aatttccaaa
     4321 acctgatcat ttcgatgaga gaccaaaaaa tgacggccac cttgatttga aatgacttcc
     4381 aataggtcag aaactccttc aaataaaatc gggtgttcaa gctctctggc ttcattttcc
     4441 ttgtactttt ctaaaaaatt ctctaaattg ggagcgaatg tctcaatcgc aaaagaagta
     4501 gaaaccttta aagcttgata gacactgtca tggtcttgtg tgataccata cagtgccaat
     4561 gtttcaacaa atgcagctgt tgaagtttca taattatcca gtaaagttcc acctaaatcc
     4621 cagatgtaat cgtgatattt catacccttc attatagcat ttttttatga aaaaagcgat
     4681 gatttccctg agttttccac ataaaaaacg agagaataac tcccgtttta ctgattttta
     4741 ccaaagacat ctcgatagag cattcctgtt cgtaaactct ctgcgtcccc tcctagttgc
     4801 tccaccaact cgtaggcaaa ggcaagggct gttgaaggac cccgactggt tgtcaactga
     4861 ccatctacca ctactgtttc cttgacgtag tgaccatcaa ggatttgctc ttgaacgccg
     4921 tcataacaag tgtatcgctt atttttcaat atctctgctt gattgagggc aattggtgcc
     4981 gcacaaatgg ctgctagttt cttcccttct tgctcgaagc tttgcaattc ttgaatcaag
     5041 gtctgattat cacgtaaatg tgcagaacca ggcatacctc caggaagaac aatcatatca
     5101 tagtctgata aatttccatc aaagacatga tctgctctta cttggattgc atgcgaaccc
     5161 gttacttgct cttcaaaacc aaccatatca catgtgatat tggctcgacg caagacatct
     5221 acaactgtca aggcttcaat ttcttcaaag ccctgagcta acataactgc tacttttacc
     5281 atgattttct ccttatttaa tttgttttaa tacaaccttt ttccgtttga atgggacttt
     5341 tccgctcttt tcttcagcta gattagtctg gtaactcatc gataaaagca aaccaacacc
     5401 aatcagatta ctgataatag ctgatccccc ttgcgaaatg aaaggcaagg gaatccccgt
     5461 caaaggaagt agtccagtca cagcaccgat attctcaaag atgtggaaga gcaacatcat
     5521 aatcaaacct gtggaaatat aagtgtagaa ctggttattt gatttaagag taatcttcaa
     5581 catacggtaa atcaacatga gatagagggc aataaccagg acagagccaa taaagccaaa
     5641 atcttctgca ataaccgtaa aaatcatatc tgactctcga actgggataa gcagattcga
     5701 agcattaaat ccctgaccaa ataagccacc actcccaatg gcaatctgcc cttgagcctg
     5761 ctggtaagtc gttgtttggg caaactcaaa gggattgagc caagccaaaa tccgattgat
     5821 ttggtaggtc ggcattccaa tctggtgaag aaaagctcgt ccgtccttgc taataaagat
     5881 agctaagaaa ccagcaactc ctgttacagc agtcacaaat attgggataa taattttcca
     5941 agaaacccct gataataaaa cgattcctga gaaaatggct acaaaaacca aagccgtccc
     6001 caagtcactt tgaagtgcta aaagaactag gactggaatg gtaaagagaa tcatccagaa
     6061 aattaacaaa aagtccagcg gaaccgtgcg tctccattcc ttatgtttct ttgtaaattg
     6121 gacaatgaca cgagccaaca tgaggatata agatatcttc ataaattctg acggttggaa
     6181 tagggtaatt ccatttattg atacccagtt tttggcaccc gttgatgcaa ctaatcttgg
     6241 attataaaat acaatcggca agatcataag tcccaagcct aaaatatata gaaagggggt
     6301 caccttccaa agaaattctg tattaaagag catgaccaca aaaccaatca caagccccaa
     6361 ggcaatccag gcgacctgct gccctaaaat gggcaaaata ttattgggat aatcatgact
     6421 aacggctata tagatagcca ccacaccgat gaccagtaga aaaaatactg gcaagagcaa
     6481 actgtaatcg actcttgagt cgagagaacg tttcatatat actaacctta tactttcata
     6541 caatactatt tatcaaagtt cattaaaaaa tctatcaata gcctcgtcaa cttcggatcg
     6601 agagatggtt ttaacagtcg cttcttctgc tagagatact actatttgtt tgccgtatcg
     6661 ttttccgacg attctcctat ccaaaataag agttaaggaa cgttggtatt cacgtctcat
     6721 acttcttccc aaagcctgtt ttaaacgaat aatggccatt ggcaattgat aatcataaaa
     6781 ggcatttttc ccttcttgat tcagttcttg attaatcttt ttcgtcaagg gttcttgagg
     6841 attttggaaa ggaagcctcg gtacaacttg aatcacaaaa ggatggcttg aaaaatcaac
     6901 tccctcccag aaacttgctg caccaagcaa gatttgttgt tcaccttttt caaagcgttt
     6961 ctttagctga tgaacatccc catttttata ctgggccaag tggctaactg taagtaaatc
     7021 cgatactgct agaagcatgt ctttagcggt aaagagaacc aaaatcggtt gctggaaagc
     7081 ttgaatttcc actagtaaag cagctacctc tctggcatag acttctaagg aggtttctgt
     7141 taccagaggg aaatctttga ccatgaccac ttcttgttcc tgttttcccc gagattcaat
     7201 cttgacaaat ttggcttcag gatagcctaa aaggtctgcc aaagaaaccc tctgactaat
     7261 ctcaagagta gccgatactc ccaagacttg gcaactctca ggaagtaaag aggacagaag
     7321 agtacggcat gattttgtag aagaaatctg aattttcttt tgactcgttt cagttacttc
     7381 aagccagtaa tcaccttcag ctgtaaaata gcgaaccagc tcatcaaagc cttctacttc
     7441 taattctgaa aaatactgat ggagattgtc cagagaatct aagatatttt tcctagattt
     7501 accagactga aattgttcta tcaagtagag acactcaaag cgaatacttt ctagtatccg
     7561 ttgttgaacc ctgttttctt ctcctactaa agccttatca attaaatcga taatagattg
     7621 tatatcgtag gtctcttgaa gcagattttc tagagctaac aaaatctttt ggacttcatc
     7681 aataatcagt aaacggtcac tgacaaattc aggattatct tcaagtctgg tcacgagata
     7741 ggcatgatta gtcactaaaa gcttgcaagt ctctgccctt tcttgactac gtttccaaaa
     7801 atcttccgtc acaaataagc tctgggatga taaattccca tcatgacgaa ggtctgctag
     7861 aaaatgttgg taacggtaga gttgcccgat ttcatccaaa tctcctgtct ctgtctcagt
     7921 aagccagacc aagacttgca ttttaaagcg tctaaataag cgattttcat cattttcctg
     7981 caaggaatga taaaaggcat ccaacttcag ataattttgt ggtcccttta agctatgaat
     8041 atctgtatgg aacacttcct tgaggcgttt accttcttct tccatgattt gattttgaag
     8101 aatctttgtc ggaacactaa gaacaatttg tcgctctttg gattgagata aagcgggtaa
     8161 gagatagcca taggttttcc caatccctgt cggcgcttga atcagagaga caggttcatc
     8221 tttcaatagc aagccaacct ctttagcaaa actttcttgt tcctccctca cttcaaggtt
     8281 caacagagaa atatttttag aaaagtcttg agatagtttt cgtggctcca gagaagctgc
     8341 cgttttctta aaatacagac cttgaacttg gaccaagtct ggagaactca ggatagattg
     8401 gttgcgataa gtttcctcaa taaccaggta ggactcatat aggagagcgt cagccatttc
     8461 cagcaagcgt tccaagagac ctttaggaag ctgggtcatc ttttcccgta aaaaaagaag
     8521 taattctgct gtagcttggg catctgaaag ggctgtgtgt gcgtgtttaa gaggaattcc
     8581 taattctcga cacaaaatcg gcaagctata tttttccagt tcagggaaaa agacctgggc
     8641 caattcgacc gtatcaacac gagggtttct tagctcatag ccttcaaaaa ataaattttc
     8701 cgccaagaga ttagcatcaa actgaacatt atgggctaca aaaatcccat cctccaccaa
     8761 gtcaaatatt tttctggcaa cttgcgaaaa atcaggtgct tgcgccagac gttggtctgt
     8821 caatcctgtc agttctttga tatgagcatc caagggttca tgtggattga catccgtcgt
     8881 atagtgatcg acgatttctc cgtcctcaat cacgacaatt cccacttgga taattttagc
     8941 cttactacct gtgctagttg cctctaaatc caccacaaca tagcgattac caatcgtttt
     9001 cattataaaa aattatacca aaaaaagggc catttggcac ctgcaaacat aggataattt
     9061 tcaaactcaa gaacactact tttcttaaaa atcccatcga atagagcatt ctagcctgct
     9121 gatttttgta aaatagtgaa gaaatacgaa aaattgagag aagaaatgtt tgcatcttcc
     9181 ttctctcaac gaatcatgta ttttatctaa ccatgtcagg atcgtagtca taaaatcctg
     9241 tatcaaggaa acggttttta gggtgaagtt tacgaacttc ttcatccagc aagaaggctt
     9301 gatcatggct aaagttgccc tcttgaatca agttacgcgc ttggataaag agttttgcaa
     9361 tctcaacaaa gttctgacca ggagtgtaga gcccttctag tttccagcga gtaaagccat
     9421 gctccaccaa ttctgttaat ttgatcatca aatcaaggtc attgttggca aagatatggg
     9481 tcccatgatt atcttcaaaa atggaatagt ggctctctgg atcacttggc tcagccaaga
     9541 agaggtcacg tttatgcgtc ttttcatcat cgatatgtgt aaagttatag tagttttgca
     9601 agagtggacg tttagaatga tggatgacgc tagcaccgta aaccaaaact tcagcaggaa
     9661 tttccaaaat ctctggcatt ttgaaaagtt cagctgatgg aatttcacgc gccaaaacag
     9721 cctcagatgc gccagccttt tgtccccaga agttaatctg acgactgcta gttaccatgg
     9781 ttgaagcatc gtagatggtc ttaaatgaat aaccatcgcg gttaactacg taaaagacgc
     9841 ctgcatcccc aatcgtaata tagtctgtct tgatttcttc caagaagtct aagaaaggct
     9901 tgatacggtc catcatatct tggtgcatga gagcattgac cgcaacgatc aattccttac
     9961 cagcatcatg aaccaactta gcgatttcac gtaattggtc ataactaaag gtcgttggca
    10021 gacgaaggcc aaaatctttc tcaccgacat agatacggtc tacgccagct tcgagtagtt
    10081 gttcaacttg ttcaatactt tcagcagttg ctgtaatgac aatcttttcc ataagaaaaa
    10141 ttataccaca tttctccaaa atcatccatg ctttgaaaat gaaaagggac tttattcttt
    10201 ttgtaacctt tctgtaataa ttctctgccg aaaaaatgat aaaataggta tgtactgtta
    10261 aggagagaat tatgcccgta agaaaattac aatcctatga ggtagactat caagaagaat
    10321 taaaccagca gcttcctcat taccaagctt atacacctga agcgcaatct gatgccaatc
    10381 tcaaggaaat cctatttttt attaatatcg ctgttttttg tatctgtatt gctatcttta
    10441 gttttatctt tttagcatta aaattatcaa ctgctcttgc ctttgccgca gcaatcggat
    10501 tcagcttact tgttttaaaa gttcaacggt ctattatcaa acgaaaacgt agaagataaa
    10561 tccaaaatat cgccccagtt ggagcgatat ttttattttt tctttttaga tggtgtctga
    10621 atggcaatct tcacttcaaa gattgttccc ttgggtttat tatctttgac agtaacagtt
    10681 ccttttagag catctacaat ttgcttggct agggataatc ctaaaccaaa accacctttt
    10741 tgccgggttc tagccttgtc tactcgataa aaacggtcaa aaattttctt tttatcttct
    10801 gtcgaaatac cgattccatt atcagaaaca agtaaataaa gattgcgatc ggtcgccgag
    10861 ataagaaaat caatttcacc atcctcctca gtatacttga cggcattatc gaaaagaatg
    10921 gtcatcagtt gtttcagaag aagctgatct gtgacaattg ttcgatggat acgattttca
    10981 aaacggaaga cacgattatt ttccgaagca atcatctcgt agtttgtgaa agttgtatta
    11041 aaaaagctag ttggaacttc tgcaagctcc ggcttaatcc catcatctct ccgagctaag
    11101 ttcagcaagc ttgtcgttaa aaaacgcata tttcggactt cttccaaact cgatgcaatg
    11161 ctttcgctca catccataat ggtagcttct ggcttacgaa aaagggtctc taagcgattt
    11221 tgcaaaactg cgagtggagt tcgtaactca tgactggcat tttccacaaa agactgttgc
    11281 ttctgcatac tctcaagcag gggcctaaca ctgaccctag ctagatagag actggcaagt
    11341 aaagacaaaa tccagaaact agccatcacg accacaatca attgctcatg cttttgacta
    11401 gcctgttcca actgactggt attaatcaag acagcagcat acttgatatt ggttgaaacc
    11461 gaactaatat tggtctccat caaaatcaca cgatagattt cttcctgccc atagctatta
    11521 aaaacctgaa tctggtagat atgtcctagt tctttctttt ctaacttaat cttatccaag
    11581 cccaaaaatc gatttccaga aagaagttga gtaaagtctt tatcaaagag aatgacttcc
    11641 gtattggaac tgacattagg ttttatttct actttactag cgtccgccct agcattttct
    11701 aaatctttaa tctcttctgt tgccctattt atagccagct gaataactgc ttgaggattt
    11761 tcactcagtc catgaagctt atcgtccacc gaagtataaa gactcgaatg catgacttgt
    11821 aaaataatca gagtcattgt agaaaaaatc agggtgaaga caccgaagtt gcggataaaa
    11881 taactaaagt catccgcata ccatgttttt ttaagtttac tgaacatctt ttaaaagata
    11941 cccaacacta cgcaaagttt gcaaattctc tgcaaaagtg gttcccttta atttcttacg
    12001 gacttttgaa atatagactt cgacaaccga aatcgttgta tcactatcaa atccccatag
    12061 acggtcaaaa atctgcgtct taggtaaaat cacattttga ttttgaagga aataaactag
    12121 taaatcgaac tctttcccca gcaattcgac aggagtatct tcaactttaa cggtattggt
    12181 tgataaatta accacgatat tcccataagt caaggtgttt tcattaaact tccctgaacg
    12241 tttgagaaga gcctgaatcc gcattttaag ttcttctagg tagaaaggtt tggtcagata
    12301 atcatccgct cccagttcaa atccatgtcc cttgtcatcc aaactttcct tggcagtcat
    12361 aatcagaact ggtgtcgtaa ttcccttttc acgcaattct tttaagactt ggaaaccatt
    12421 tttttctggc aacatcaaat ccagcaaaat caagtcatag acaccactct cagcttcgta
    12481 gagaccttct tctccatcaa atacctgcat aacatccgca aaatcgtcta aaaagtcaaa
    12541 tactgaattt gacagaccta ggtcatcctc aaccaataag atttttatca tgagaaactc
    12601 ctccttatta aaactattat accaaatttg ccttaaaaaa aactcaactc tctgcatttt
    12661 acatgagata gctgagtttt ctttttattt taggcttatt tatgcatttc cgtattgaag
    12721 aacaactgct tcgactgcag ctttttcacg gctaatcaag tcaacacgcg ctgcaatttc
    12781 cttgattccc ataccgatgt tacggctaag agcaaggtca gaaagttgcg gctcaaagaa
    12841 ctccttgtat tccgccaagc gttgctgagt cttaaataca tgagcaggaa ggataacaaa
    12901 gctatcaaag ctcatatctc ctccaagggc tgccttaatc caagcccagt tttcacgcgc
    12961 ccaagaccaa gctgttttct gagttgcttg atgagctagg aattggtaat accaagcaga
    13021 caagtcctgt ggtttgacca caaatttgtc cttccaagaa gtaatcaggt tttggatatt
    13081 atccgcatct gtactgtatg caagagctgc tgccaactgg cgtttaaaga cagcatctgt
    13141 tgcgtgagta taagtatcaa gataaagtgc taacaagtct ttagtctcat gatgtttcat
    13201 ctcattaatc agaacttgtg agcgaatagc tgctgggagt cctgcaagat tctccttgtg
    13261 tgttgcgaag atttggctag cgacttgact agcttctgca tcatttgagc gaatcatcat
    13321 cgaaacagcc agctgacgaa ccaattcatc ctcatctgat tctccgtctt tagcttcaaa
    13381 accaagacgg tcatagttat gacgagccaa tttagcaacc agtcctttga aggctgtttc
    13441 agcatccgtt ccttcatcaa taaagcgctc aagggctgaa atcacttgag aaacagctga
    13501 aaccaccaga taagactctt ccttagcaag tttatcaaga actggaagca agtctgcata
    13561 agaaatgtgc cctgcctcag ccaacaaacg acgttcttga acaatttgca gtttgcttgt
    13621 gttatcaagt gtctctagct cagcaagaac agcttctaac aagtctcctt gatagtcggt
    13681 aatatagtgg gcagtatttt cagtgttgag acgaagagct ccttcatttt cagcaagaag
    13741 agctgcgtag ccagggattt cgatactttc agtttcgagt gtatcaggca agcctttcca
    13801 gttgctattg aggggcacca cccagagacg gttcttgtct tcgttctcac cgatgaagaa
    13861 ttgtttttgt gaaatcttca agacatcatt ttcaacttta acagtaagaa ctgggtaacc
    13921 aggctgttcc aaccaagaat ccatgaaggc tgcgacatca cgtcctgacg cttgaccaag
    13981 ggcatcccaa aggtcactac caatggtgtt gctgtattgg tgtttttcaa agtaggcgtg
    14041 caaaccttta gcaaaatcag catctcctag ccaacggcga agcatgtgca tgagacggct
    14101 tcctttggca tagacgatag cgccgtcaaa gagtgtattg atttcatctg gatgtttaac
    14161 ttcgacgtgg acagactgaa cgccatcagt agcgtcacgt tcaagagcaa gaggtactcc
    14221 acctgtttgg aaatcttcaa agatattcca gcttggttcg atggtatcca cacagacgta
    14281 ttccatcata ttagcgaaac tttcattgag ccaaaggtca tcccaccatt tcatagtcac
    14341 gaggttccca aaccattggt gagccaattc atgggccaca acaagggcaa cttgttgacg
    14401 gctagcaaat gtagagttct catcgacaac caagtaaact tcacggtagg tcacaagacc
    14461 ccagttttcc atagcaccag ctgagaagtc aggaagggcg atgtggagag attgaggaat
    14521 tgggtactta actccatagt aatcttcgta aaactcgata gagcgaacag cgatatccag
    14581 tgagaaatca agatttgaaa gtggatgtgc tttggttgag tagacaccta ccagggtacc
    14641 atttttagtt ttagcggtca ccccttgcaa atcaccagca acaaaggcca acaagtaaga
    14701 agacatgcga ggtgttgtct caaacttcca gatacctgtt tccttacggt tttcaacatc
    14761 gatttctggc atgtttgaca aggccaattc accttctgct tggtcaaagc gaagagagag
    14821 gtcaaaagtt gctttggctt caggctcatc cacacatggg aaagcttcgc gcgcaaaatg
    14881 gctctcgaac tgagtagaca agacctcctt cttgactcca tcaactgtat aataagaagg
    14941 gtaaatccct gtcatgttgt ctgtaatttt accagaaaag gcaagaacca attcaacttg
    15001 accagcctca gccaattcga tatgaagggc ttcattgtca tggtcaactg taaatggacg
    15061 agcttgacct gcaacttcta cagaggtgat ttccaagtct ttttggtgga gggagatgcg
    15121 gtcactctgt gcttgaccag tgatggtcac tttcccagaa aaagtcttgg tctcacgact
    15181 caaatctaaa aataaatcat aatgttcagg aacaaattgc ttaataaaat gttcaactgc
    15241 ttgcatagtt ttctcctatt ctaagtttaa gagctgctgc tcttcttcaa acaaacttat
    15301 tatatcatat tttgcttgag aaaaaaggat tggacagcga tttccaaaac tttcttcctt
    15361 ctaatagtct acagtgggta gaccttgcga aattcttcta aaacaacctt gctttcaggt
    15421 gtaaaagtca gccctacttc acccaaacag tctgtgaaaa agtcctcatg aacctggcgc
    15481 caataggcaa gtgatttgtc tccctcacct tccttaaagg catgttgcgc agaaacttga
    15541 ttgaagagtt caacagaaac ctttgtaatt tcgacaatgc agacagactg attttgacta
    15601 tctaaaatga catcgaaggt ccctacttgg ggaagtggtt cgtcttctag tacatagagg
    15661 tcataggctg atgctgttgc tgtcttttct cctttaaaca ccaaatccgc taaaaggtct
    15721 ggttcaactc caaaagccca agcatcgatt tcatctccga tcaaaggatt gatttgcttg
    15781 tatttattcc acatttcttg cggtatcatg ggtactcctt tgtaattttt tactttcttc
    15841 ttttatgtgt ttaagatgat ctggatggtc aatctctaaa tcaaaaatct ctggaataga
    15901 actgtagtgg ataatgcact tgatacccaa ctgattcatt ttttgtatga aagaagtatt
    15961 cagatagcct gctacagcaa aatcaatctt gttctttctt gctttatcct gcatatctct
    16021 tagcatatct aacattattg gactttccat atcatgccat tgactgtttc tcatagtcgc
    16081 aaaaacaaag gaagtcaaat cattcattcc aactacaatc tttgaaatgc ccgtttccag
    16141 tatcctatcc aagtcaaaat acgctgacgg taattcaatc atcgttccga ctttcccagt
    16201 aaagccatac tgacgcaata ctgtaatagc ttgttttaat tggtcggcat cattgacaaa
    16261 aggaaagata agagatagat tgggattggt ttgataaact tctgtaacga catgtgcttc
    16321 agcctgaaat tcatccaaac acgccagtaa acgcctggtt cctctatagc caaacaaggg
    16381 atgcccttcg tcaaaaaact ctctagtccc cactaaacaa ttggcttctg tattcgttaa
    16441 ttcagaaaaa cgataccaaa cttcttcatc tgagtacagg gagcagatag tctctagata
    16501 atcttttaca aattgctgac aacttgctaa tatgatgttt tgattaagct ctctcaacaa
    16561 atattcccca cgaatcatgc cgacgtggtg aaatagttga ggataaattt tttcaagaat
    16621 tttttcgcca ctaagggcaa gttgatttct catcattcac cttccaattc atgtaagaag
    16681 tcttgtccag ttctggaaat cctaataatt cagacttaac cttcaagact aatggcgatg
    16741 cattttcttc tgtaatctct tgaatatcca tccaaatata tccaagtgaa tcattcgcac
    16801 catcagacac agcttccgaa gtcgtaactt gaggtgcact ctcattcatt tcaacatcat
    16861 acaaggccat gacatggtga accataaaat ttgttaactc ttctctgacg aaaacatcgt
    16921 agattcgagg attagagtag cttctaacag taaatcccgt ctcttccata acttctctag
    16981 tcagcgtttc cgtcagtcct tcaccaagtt gctgactgcc tccaggtaga tcataccgat
    17041 gttgataagg gcctctcgtt ttttcaatgc agagtaactt cccattttct aagcaaacag
    17101 cgtagactcc aaagtgtttt ttgatttcca tccaactcct cctacttcaa agaccagcca
    17161 ccatctattg tcaagatttg tccttgcatg gcgctcgctt ttccacttgc taaaaaaaga
    17221 ctaagctctg ctatttcctc tggctcaatc cagcgcttga ttggggtttc actagccacc
    17281 cagtcagcca aaccacctgg ttcaaaatcc gcagcggtca tagctgtctt gactgctcct
    17341 ggagcgatac caaagacctg aatcccagct tcagcatagt ctagagccaa ctgcttggtg
    17401 aagccagcca aggcatgctt ggatgaagta taggcgtgac cacctccacc tgctaggcta
    17461 gaagcaatgg aacacatatt gatgatgatt ccctttttat tttccagcat ttgtgtcaaa
    17521 taataccgag tcaactcaac aggagtcatg tagttaattt caaaaatctc ttgaatttcc
    17581 tgcgcagtct gttccaacag tggtttgtaa gcatccaaaa ctccggcagt attacacaaa
    17641 acatccacct gagggcacca gtcaaaaata ggttccaagt ccaaggtcaa atctctctgt
    17701 aaaaagtgaa aatcaccctc taagagtggc ttttcacctt ggtcaactcc ataaacttga
    17761 tagcccttct ctaaaaagag gcgagcttga gccaatccga tccctgaact cactcctgta
    17821 atgagtacac gtttagtcat gcacttctac ccaatccgtt gccaaaacat cacaagctgt
    17881 cgggctccac atggaaaaac cttctccttc tccagacacg ttgattaaga aataaggtgt
    17941 cacttcaagt gcaagcccat tttgctcgat ggtatcaaag agttggacat agttttcagc
    18001 acctccccaa ccagttcgta catatttttt cttagccttt aagccaggta gaatttcttc
    18061 aaatgtcatg tttttctcct ttaatgtcaa taattctccc cttcattata acaaaaaaac
    18121 cgctttaaaa cggctttttg actgtgattt atttacatct tcttctactt acggcaaatt
    18181 attccctgca gcaagataaa tttcatacca ttcttttctt gttaagctaa agtttgccgc
    18241 ttggctaact tctctcaagt gcttaggatt tgtggtacct acaactgcct gcatttttgc
    18301 tggataacgc aatatccaag aaatggcaat agttgaagag gttactccat atttaatagc
    18361 taaacgatca agtacttgat ttaaagcttg aaatttctca tttccaacaa agttcccttt
    18421 aaaatacccg aattgcaaga cagaccatgc ttgaatgacc acatcgtgta atttgcaata
    18481 ttcaaaaatg ctgccatctc gcatagctgc ttgactatct tccatattaa catgaaaagc
    18541 tgattcaaat cctggagtaa aagccgcact caattgtagc tgattaacag ctaacggctg
    18601 cttgacatct tttttaagca actccatcat cataggattt tgattagaaa ctccaaaatc
    18661 tcgaacttta ccttgtttat aaaggagatc aaaggcttct gctacttggt cagattccat
    18721 caaagcatct ggtcgatgaa ggagcaagct atctagatga tcaatcttca atctttgcaa
    18781 aataccgtct actgatttta taatatagtc cttagaaaaa tcaaaatagg taaattcttc
    18841 aatgcgaatg ccacatttgg actgaatcca catcttttct cttaaatctg gacgattttt
    18901 taggacaaga cctaacagtt cttcacaacg accacgacca taaatatcag ccaagtcgaa
    18961 ggcattgatt ccaacagaaa gtgctgtttc tacaagctct tcaacttctt ttacagactt
    19021 atcttttatt ctcatcattc cgagaacaat ttctgataat tctttgtcat cttgaccaag
    19081 agttatgtat ctcatcaaat ttttctcctt taatttctaa cattcttccc ttcattataa
    19141 caaaaaaccg ctttgcaacg gctttttgac tatacttcac tccattttat cttcttaaac
    19201 ccacggaaca agacaaagat tccaataaag aggacagcta aaggaataac ttttgtaagg
    19261 aaaacatttg aaattcccat ccactcataa taacggagca gagaacccac cacaagatgg
    19321 gcaataatca tactgacaaa tggacgaaag accgcttctt tccaattcca aataccgata
    19381 actagcgaaa tcgtaaagac agacaaacta tcccagggag ccggaatata aaaggctcct
    19441 tcttgtatga agcttgccat tcctacatat cctaaaacaa ctagaagaac tatagtccca
    19501 acaacaatgt aagtgccaat tttcatttta ggagaatctt ggactaaact tcttcgtaaa
    19561 attgtggcca caagtccaaa tccaatcaga aaaataagaa gttgccctaa aaatgtgagc
    19621 aaattgactg ttaagagagg acctttagaa aaatcactta gtagttgata ataacgtaat
    19681 accgccagga caagaattgg cgtcaaaagg gactctttga tagaactgcg aggtgctccc
    19741 ttgagaatct ctttcattat ttttttagga ttcttaccta gataatcctc tgcactcatg
    19801 ccatctcgtt ctgcttctga gaaatctagc atcatcaaat agatctgctc tctgagatag
    19861 tcttcatcat agagaaatcc agcaagatta aaactttccc acaactcctc aaaatacttt
    19921 tgattctcct cagaaaactc atgtagcaaa gcgcttgttt cttcgtaata cttcattttc
    19981 ttcatggttt aacccccatt cttaatccct tctacttttt gactcaaatc gtcccattgt
    20041 tgccaaaaga ctgagacacg ctcttctcct tctttcatta atgaaaaata cttccgatct
    20101 ggaccatctg gcgacgggcg catgtcgcct cttatccatt gatttttttc taacttttgc
    20161 aacaaaggat aaatagttcc tggaacgata gtatcaaatc cagcctctcg caaagtctga
    20221 accaactcat aaccataccg ctctttttga ccaatcatat ccaagacaca accttcaaga
    20281 acacctttta atagctgagt ttctttcatc acttctccct tctaatctat tttgtaatac
    20341 ctactagtaa cttcacctat agtatatcac ttctacacta gtttgtaaag cataatagtt
    20401 aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cctaccgtat gtatggttac
    20461 tgacttcgtc agtttcatct acaacctcaa aacagtgttt tgagcaacct gcggctagct
    20521 tcctagtttg ctctttgatt ttcattgagt ataaataaaa aaacagaact agtctgaact
    20581 agtcctgtct acttttaccc aatcacactt ccatttggta cagctggatc aactgtgaga
    20641 agggttaatt tgccatcatg ttcagctgat agaatcatac cctggctgac atattttttc
    20701 atcattttac gtggtttgag gttagcaacg atttgaactt tcttgccgac caattcttgt
    20761 tcatttggat agtattttgc aattcctgaa agaatctgac gatcttctcc atcaccagca
    20821 tccaagcgga attgaagcaa cttatctgaa ccttctactt tagacacttc tttgacttct
    20881 gcgacacgga tttcaacctt gtcaaagtct tcaaacttga tttcatcctt gtttagtttg
    20941 agctcaactt cgtccggatt ccattctttt tcgactgctg gtttattgcc ttccatttgt
    21001 tccttgatat aggcgatttc ttcttccata tttagacgtg gaaagatagg tgttcctttg
    21061 gcaactacag tcacatctgc tgggaagtca gccaaactca agttttcaag actagaaact
    21121 tcttccaaac caagttgagt caaaactgca cgactagttt ccatcataaa tggttcaatc
    21181 aagtgagcaa ctacacgaat gctggctgcc aagtggctca tgacacttgc caattggtca
    21241 cgaagagctt catccttggc caagacccat ggtgcggtct catcgatgta tttattggta
    21301 cgagagatca gagtccagac tgcttcaagc gcacgtggat agtcaactgc ttccatgtgt
    21361 gtatggaagt ctgcgattga ttgttctgca acctcagcaa gaacatgatc aaattcagtc
    21421 acaccttcta cataggcagg gatttgtcca tcaaagtact tattaatcat ggaaaccgta
    21481 cggttaagga ggttcccaag gtcattagcc aattcatagt tgatacggcc gacatagtct
    21541 tcaggagtaa aggttccgtc tgaaccaact ggaaggttac gcatgaggta gtaacgaagt
    21601 ggatctagtc cataacgctc taccaacatt tcagggtaaa cgacattccc ttttgactta
    21661 gacatttttc cgtctttcat gacaaaccaa ccatgggcaa tcaaacgatc aggtaattta
    21721 acatccaaca tcataagaag gattggccag tagatagagt ggaagcgaag gatatctttt
    21781 cctaccatat ggaagactgt tccattccag aacttgtcaa agttaccatg ttcgtcttga
    21841 gcgtagccaa gagctgtcgc atagttaaga agggcatcaa tccaaacgta gacaacgtgt
    21901 tttggatttg atgggacagg cactccccat gtaaaggttg tacgagatac cgccaaatct
    21961 tccaagcctg gctcgatgaa gttgcgtagc atttcattaa ggcgaccatc tggcgtgata
    22021 aattcaggat gagctttgaa aaattcgacc aaacggtctt ggtatttgct aaggcgaagg
    22081 aagtatgatt cttcagaaac ccattcaacc tcatgacctg atggagcaat accaccagtc
    22141 acatttccag cttcatcacg gaaaacttct gccagctggc tttctgtaaa gaattcttcg
    22201 tctgatactg aataccaacc agagtattca cccaagtaga tatcatcttg agcaagtaag
    22261 cgttcaaaga cctgtgcgac aactttttca tggtagtcat cggttgtacg gataaattta
    22321 tcgtatgaga tatctagtaa ttgccagagt tctttaactc caaccgccat tccatcaaca
    22381 taggcttgag gtgtaatacc agcttcttcc gctttctgct ggattttctg accatgttca
    22441 tcaagacctg tcagataaaa tacatcgtag cccatcaggc gtttgtaacg tgctaggaca
    22501 tcacatgcga tagttgtgta ggcagaaccg atatgaagtt tcccagatgg atagtaaatc
    22561 ggcgttgtaa tataaaaatt tttttcagac ataatttttc ctttccaggc aaatgaaacc
    22621 tgtttttcta acacttcatt atatcacatt tttaatgaat ttcgataggg aaatccatac
    22681 aaaaacaaga tagacgagtg tccatcttgt tgatctcatt cataacgaag ggcttcaatt
    22741 ggatcaagtt tcgatgcctt gttggctggc aagactccaa aaatcatacc aacactagcc
    22801 gaaactgcaa gactaaatag ggcaactggg attgatactc caacttctat accttctatt
    22861 aaaccttgca gtaacaaacc tgctaaggca gttaaaccac ttgcaattgt caagccaatt
    22921 aagccaccta acaaggtcaa aatcatggat tcaatcaaaa actgaattaa aatattggca
    22981 cgtgttgcac ccaaagcctt acgaagacca atctcacgag tgcgctctgt caccgaaacc
    23041 agcatgatgt tcatgacacc agttcctcca acaaagagag aaatccctgc gatggaacta
    23101 ataatcgtcg tcataaaact aaacgattgt tgaatttctg caaatacaac ggactcatct
    23161 gccacctggt attctccctg ttgtaagcct gcaagctctg tcatttttcg tgccagttct
    23221 ggacccagag ttggggttaa actggtatca ttcactcgaa agacaatatt agctatttca
    23281 tctacattaa aattcgcagc aagggagata ttggtagtaa taggcaagcc accaaaccca
    23341 tatatttttg atcttttagc ctccggacta gtataaaccc caatgacccg gtaactaaat
    23401 ccattgactt ctacaacctt gttaatagcc tcttgaggag attcaaataa actaatggac
    23461 aattcctcat ctagcaaaat gacacttgca aactctttga aatcttgctc tctcagacta
    23521 cgacctgcaa taatttcatt cttaacagcg tccatgtaag ttctgtttcc acctgtcaaa
    23581 ttagcattct caaccttttt atcttgatag gtcaagatgg cattcgttga attggttaca
    23641 tagtaactat ccactccctt cagtttagct gcctcttgaa cccaggattc ttgcggtttt
    23701 ggcggttcaa caggaacttc ctcttccttt ccagaaaccg taaaagctga ttgtttctga
    23761 gtaaaagacc catctttact ttttttagga gagaaaaaga cgctaatatt tttctgagat
    23821 ttagtcatat ctttattgac ttgacgagat agggaatcac ccaaagccat aatcacaaca
    23881 actgatgaaa caccgataat aatcccaatc atagtaagca aagaacgcat cttgtgagcc
    23941 atgatagatg aaaaggcaaa tttcagattc tgcatcttag ttttcctcct ttcctaactg
    24001 agcactgtca gacgaaatga ccccatcccg aatgacaatc tgacgtttgg cataggcagc
    24061 aatctcaggc tcatgcgtta ccatgataat ggtttttcct tctttattca aatcaaccaa
    24121 taattgcata atttggttac ctgttttggt atccaaggct cctgtcggtt catccgctag
    24181 gataatagaa ggattgttta ccaaggcacg cgcaatggct acacgttgct tttgaccacc
    24241 agataattct gaaggtaaat ggtgactacg ttctgtcaat tcaaccttgt ctaaatattc
    24301 ctcagccaac ttgcgacgtt ttgaagacga aactcctgcg taaatcaagg gcaattctac
    24361 attttgcaga gcattgagct tcgatagaag aaagaactgc tgaaagacaa aaccgatttg
    24421 ttggttacgg accttagcca gttgtttttc accaagccca gccacttctt gaccttcaag
    24481 ataatattct ccactggttg gtgtatccaa catgccaatc gtattcatca gagtggactt
    24541 accagaccca gatggtccca tgatggctac aaattcaccc tcattcactt ctagattgat
    24601 atttttgaga acctgcaatt cttggtcacc attacggtag cttctgaaga tattttttag
    24661 actaattagt tgcttcatca gccttcacct cttttccttc ttccaaggaa gatgttggat
    24721 tactgatgac cttagcaccg ttcgttaaac cagaagtgat ttcttgattt tctgcgtcag
    24781 catttcccaa tgaaacctca acttttttag ccttttgttg ttcatccaca atccagacat
    24841 aatttttact atcatccatt actagactgc taacaggaac aagaatagcc ttagttttgc
    24901 ttttaacctc aatgttgaca gaaaaacctt gtttcaaatc accaacctcg cctgtcacat
    24961 caatagtata agggtattta gaacctgtat tattcccggc tgctggacta gctgcttcac
    25021 cattgttttt aggatagtca gaaatatagc ttaatttccc agtccatttt ttatcaggat
    25081 acactttaga agtaaagctt acttcttgac ctacagaaag gttggctaga ttgtactcag
    25141 acaattctcc cttgacttgt aaattttcat tgctgacaat atgaaccata acttggctcg
    25201 cccctgttgg agatttagaa acattgctat tgacttcgac tacagttccc tctagggtac
    25261 tgagaacagt tgttgcatcc aattgacttt gagccttact taattgcgcc gcagcatctg
    25321 cacgcgcatc acgggcatca cccaattgag cgtcaataga agcaacagaa tttccagcca
    25381 ctggagttgg gctttgcacc gttgcatctt ctcctcctac tggcgctggt aactgtggag
    25441 ccggagctga agcggcttca tttcgtgctt gattgagttc attgatatga cgatctgcct
    25501 tagctactgc tcgactagct gaatcatagg ccgcctgcgc ttctgaacta ctgtacttga
    25561 ctaaagcctg cccttcgctg accttatcgc ccacagaaac aaggatttca tctaaatcac
    25621 ccttactagc atcaaaataa acatattgtt cattttttgc tgttactgtc cctgacaata
    25681 aaacagagga tgccacgctt ccttccttgg caacaacaag atgagtaggc tcatctttta
    25741 gagcagtctg agaaggttgt ctaaagagta aaatcccccc ggcacccaat acaactacac
    25801 tcgcagcacc gattgctgca tacagttgcc actttttagc tttaccattc tttttcttca
    25861 taatgaaact ccttttcttt tttacaatac tttgctatta taccaaattt ccctccagca
    25921 aacaatgcag ttcagatgga aataatggca gttcaggatt aaacaatcgt tcggaatttt
    25981 gcttttctat tgtactagat atataataca ctatcttgac ttatttggca agcttttttg
    26041 caattttttg tgcgtagcag atttttgcaa tcaaatcaaa aaaagaataa aatataacta
    26101 tcaaaaaaga cactctacta tttaaaagat tacaaaggag ttttcaatga gagaatatga
    26161 tatcattgct atcggtggag gtagcggagg aatcgctacc atgaaccgtg ctggtgaaca
    26221 tggagccaaa gcagccgtta ttgaggaaaa gaaattaggt ggaacctgtg tcaacgtcgg
    26281 ttgtgttcct aaaaaaatca tgtggtacgg ggcgcaaatc gctgagactt tccatcaatt
    26341 tggagaagac tacggcttta agactactga tcttaacttt aactttgcaa ccctacgtcg
    26401 caatcgtgaa gcctacattg atcgcgctcg ttcttcttat gatggtagtt ttaaacgcaa
    26461 cggtgtagac ttgattgaag gtcatgctga atttgtagat tctcatactg taagcgtaaa
    26521 tggtgaactg attcgtgcta aacatatcgt gattgctaca ggtgcccatc caagtattcc
    26581 taatattcct ggtgctgagc taggtggctc ttctgatgat gtatttgcct gggaagaact
    26641 tccagagtca attgccattc taggcgctgg ttatatcgcc gttgaattag ctggcgtact
    26701 ccacactttt ggtgtcaaga cagatctctt tgttcgccgc gatcgtcctt tacgtggttt
    26761 tgattcctac atcgttgaag gtttggtcaa ggaaatggaa agaacaaact taccacttca
    26821 cactcacaaa gtccctgtca agttagaaaa aactactgac ggcattacca ttcatttcga
    26881 agatggtact agtcacacag ctagccaagt tatctgggct acaggtcgcc gtccaaacgt
    26941 taagggcttg caacttgaaa aagctggagt gactctgaac gaacgtggct ttatccaagt
    27001 ggatgaatac caaaatactg ttgttgaggg aatctatgct ctaggtgatg taacgggcga
    27061 gaaagaactg actccagttg caatcaaggc cggacgtacc ctatctgaac gtctctttaa
    27121 cggaaaaact actgcaaaaa tggattactc aactattcca actgttgtct tttcacaccc
    27181 tgctatcgga actgttggtt tgacagaaga gcaagctatt aaagaatacg gtcaagacca
    27241 aatcaaggtt tataaatcaa gctttgcatc tatgtactct gcttgcactc gcaaccgtca
    27301 agaatcccgt ttcaaactca taacagctgg ttcagaagaa aaagttgtcg gacttcatgg
    27361 aattggctac ggcgttgatg aaatgattca gggatttgcc gttgctatca aaatgggagc
    27421 aaccaaggct gactttgatg caactgtggc aattcaccca actgcatctg aagaatttgt
    27481 aaccatgcgt taatcgaaac aaaagaagct gatataaata tgtctgcttc ttttttaatg
    27541 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
    27601 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
    27661 actatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
    27721 ctattggggc tgctctcatt gctgttttgg cacaaatcag tcttccaatt ggacctgttc
    27781 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
    27841 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
    27901 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
    27961 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
    28021 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
    28081 tcctagctgg aatggcattt gaaaaagctc ttgttgtggg ggttcttccc tttatcattc
    28141 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
    28201 aaaatcaggc ttactttact aactaaaaaa ggataccgag ttatcatgac tcaatatcct
    28261 tttttttatt ttgaaaactt atactcaatg aaaatcaaag agcaaactag gaagctagcc
    28321 gcaggctgct caaaacactg ttttgaggtt gtagatgaaa ctgacgaagt cagtaaccat
    28381 acggcaaggc aaagctgatg cggtttgaag agattttcga agagtattag ttgcctttaa
    28441 aggcatccac catcgtttga aattcttcat ttgagagagt aatccctttg cccattttag
    28501 tatggtctgg actccaagca cgaatatcaa actttgcagg ggcaccatta aagctcacac
    28561 ggttaatttc cttggtccaa cctttttcgt tttcagaaag agtcaacaag tgctcttcga
    28621 tttcaaatgt aaattctgcc attttcttct ccttttttag tttcattagt ttattcgtaa
    28681 aatcttgtag attttaggaa aattttatat aatattgata taaaagaagg gaggccaata
    28741 tgagacataa attccagcaa gttctagata aaatacatga ttttttaaat ggacatgacc
    28801 aacctgacca gactgaaacc aactccctta cagccactat tgaagaggct atccagaaac
    28861 aaaccgctgt tcaccttatc ttgtctgaga caagctttac aggtgatatc atcaaatatg
    28921 atcagcaagg ccagcaaatt atcgtgaaaa attttgccaa aaatgtgagc cggattatcc
    28981 gtataagcga tattcaacgc ctgcgatttg tcccctcaac tgtccaaaca gcccaaaaaa
    29041 atagatttaa gaaagagtga gatgtagttg cttcatccca ctcttttttc ttagcgaatt
    29101 tgttcaaaat gtaaatgaac tgcgatatga tctccataac cacttctttc caagtcacgt
    29161 tgtaaacgat aggaaatgta gtgttctgca atggtaatgt aacctgcgcc caataaacga
    29221 tgttcaacca tagattgaat catactgata gtcgcacgtt ccaccttggc ttcttgtaaa
    29281 tccaaaacta ccttcttagt gacttgagca agattttgac gcaaatcatc tgtcaaaaca
    29341 taaacagttt gggctgcctt caagatggct tggtaaatct tatctggatt aaattcagca
    29401 atttcgccat tacgtttgat tacttgcata ggtttctcct ttattctttg ttttctttga
    29461 tttctgccag cattttttct tcttctactg tcagttgata atgttcaagt aaatccggtc
    29521 tgcgctcgta ggttttcttt aaactctcgt acaatcgcca ctgacgaatc ttttcatggt
    29581 ggccactcat caatacatct ggcacgacca tgcctcgata atcataggga cgtgtgtact
    29641 gaggatattc taaaagacct gaagaaaaac tatcatcttg gtggctagac tccttgccaa
    29701 tcacttctgg aatcaggcga actgtagcat caatcatggt catagctgcc aattctccac
    29761 cagtgaggac atagtcgcct agggaaatct catctgttac caaggtctta atgcgctcat
    29821 cataaccctc atagtgccca cagataaaga ttagctcttc ctcttgagcc aaatcttcag
    29881 cataagcctg atcaaactgc tttccagcag gatcgaggag aataacgcgc ggatttttct
    29941 tttcaatagc atcaaaggaa tcgaaaatag gttgtgctct gagcaacatg ccctgaccgc
    30001 ctccgtaggg ctcatcatct acatgacggg ccttttcagc attttctcga aaattatgat
    30061 actggatatc caagagccct ttttctcgag cctttccaac gattgagtgc tccagtggag
    30121 aaaacatctc tggaaagagg gttaaaatat caatcttcat cgtctaaccc ttctaagatt
    30181 tccacatcga cccgtttatt tggaatatca acattgagaa ccactggtgg gatataaggt
    30241 aaaagcaaat cacgtttgcc ttttcgtttg accacccaga catcattagc acctggttgc
    30301 aggatttcct tgatggttcc aaccaagcta tcaccctcat agacttccaa accgataatc
    30361 tcgtgatagt aaaattcacc atcgtctagg tcattcaaat cttcctcagc gaccttgaga
    30421 ctgtatccct tgtacttttc gatagtattg atatggtaca tatctttgaa tttaataatg
    30481 tcaaagttct tctgtttacg gtggctagcg atggtcactg tttggacaaa ctgatctttt
    30541 tcatcaaaca aagtcagctc agctcctttt ttaaaccgtt cttctgcaaa atccgtcaca
    30601 gacaatactc gcatctcacc ctgtaatccc tgcgtattaa cgattttccc aacattaaag
    30661 tagttcatct tgtctcctgt aatctccttt ttccatctta ttctgacaat tctcgaataa
    30721 tagccgcaat tttttccgat tctgaccatt gtaaataatg gtgattcctt cctaaaatga
    30781 gtttagtatt ggaagtccaa tattctgatt ctctgtactc tttttctcta taagtctgac
    30841 aaaaaataaa tacagggaca tgagattcta tcgacaaatt ctcaaaatct tcctcagtaa
    30901 tctctccaga tatctgaaat tctggatctt gattttccaa ctctaagcct ttttcttgca
    30961 ttaattccca gattttttta ttcgtttcag gactaaatgt tgcttgagtt aagttcttaa
    31021 aataaagttc aggaccacac tcgtcaatca gcctcatctg ctcttccatt tctggataag
    31081 gattttctga aaaatcagca aacatgactt ttttagttgt cggttcaatt gctactaaag
    31141 tctgacactt aattggtttc tcgagtaatt tgcaagctaa aattccactc caactatgtg
    31201 cacaaagtat atattcagaa attcctaatt cttcaagtac ttcataaacc gcatctgcaa
    31261 gattatctag attttttcca gcttggtcat gaatcggact cctacctgtg ttcggaaaat
    31321 caattgtcaa ataaccaatt gtaggaggag gtttttcaag tataagtgaa aaattttcat
    31381 aacttggtag caaacctgct ccgtttagac aaactagcac tttcttttgc tttttataag
    31441 taacagagag gctaccaatt tctgtagata cttcaaacct cttcataaag aaatccactc
    31501 attctatata atgaattatt aaaaatcctt atcctttatt ttatcacgtt ccaaagattt
    31561 tctcaagttg gaggaagggg acaatatctc tactttccct tcaagaatcc ttccaaatca
    31621 tgtttatgtt ggtaattaac ggctgcggtt ttgtctttct caaagatggt tctagttagg
    31681 tcaatatgct tgatagcagc aatagcgacg gtgtagtgaa tgatattagc cagttctatg
    31741 gcaggttcct cgttcgaatc ctatcccttc ttttcgacca gagcgcctat tcaaaacctc
    31801 ggctacttct ccgacttcct ccactaactt cataaagaga ccttcatcag tccgagactg
    31861 ctgttaatgt tcgagtaagt agtcttggaa ttgcctaaac gttcaatctt ttatagtata
    31921 ttgaaactag aatagtacac ctttacttct aaaacattgt tagaaatcga tttgactgtc
    31981 ctgatcgatt tgtcctgtta ttatttcatt ttactatatc ttctattcca cacaaaaaag
    32041 cgagacatcc gtcccgccct tcttattttt cgtcaataac gattcttact tttttgtatt
    32101 cagttgggac agagtagaca atcgttctta tcgcagaaat agtgcgaccc ttacgaccga
    32161 ttacacgacc cacatcgctt tgatcaagat tcaaatgata ttccaaaaat tctggtgtat
    32221 cctcaatctt gatagttaag gcatctggtt gtgaaattaa gggtttcaca atcgcaataa
    32281 tgagattttc aatcgtatcc atctgtcaac ctactttaaa cttattttga gaatttagaa
    32341 tcgtggaatt ttttcaatac gccttctttt gaaaggatgt tacgtactgt gtctgaaggt
    32401 tgagctccat tagccaacca tgcaagaacg cggtcttctt tcaaagttac ttggttttca
    32461 gcaacaagtg ggttgtaagt tccaactgtt tcgatgaaac gtccgtcacg tggtgaacgt
    32521 gaatctgcta cgttgatacg gtagaaaggt tttttcttag aacccatacg agtcaaacgg
    32581 attttaactg ccatttttaa agtctcattt ctttaatttt ttatttcggt gaaatagctg
    32641 agctatttag cacatgttct attatagcag atttctggca ggtgtcaaga aaaaaacttg
    32701 acagactata aatttcttaa agcatttaga aatttgttag aataggaaat aaatgtttga
    32761 aagatgctat ccgtgaatac tattttagaa aaattttata aagaacacca agtcaaaccc
    32821 ttcatatcgc ctgaacgaga tttggatact tggcttctaa gtcccaaacc cgttcccaag
    32881 cgaaatatgg acttattagc agatgattca ctagcaggag atatcatttt actatggaga
    32941 atccagtttg gtacttttac cactgaaaca tgattttaaa aactcccatt cgaatatgat
    33001 tcaaaattcg cttagaatca atgttttccc actttttcaa aaaataaatt ttcatctaat
    33061 ttaaataact ttcaattaag tgtgaatttt gcttaaaatc attaaaaaac accccatggt
    33121 gtgaaccatg aagtgttgta aatgctgtgt tgtagctagt tcttagcgtt tagagaactg
    33181 gctagcttta cgagctttct taagatctgg ttccctaaat actttgagta cacttatggc
    33241 attgatgccc caaaacatct aaaaactctg gtagaaaaag ggtatgctct tgtcgaaact
    33301 tcttttgact cacttgacca tctaaataat accatgaaaa agaatatcct gaagaagaag
    33361 aagggagtta ctggactttc taaaatgaaa tcttgcgacc tggatcaagc ccttcatgag
    33421 catttttcag aagaagaatt agctggtcac tttcatgtcc ttctatggac ttttttacaa
    33481 tggcattgct atcacaccca atacctatct aagcgcctgg ttcgtaaact ttattgcagc
    33541 tcttcctcta aatttcctaa ttgttgaacc aattgcccgt tttatactaa gttcttttca
    33601 gaaaccattt actggggaag aagttgaaga ttttcaagat gatgatgaaa tcccaactat
    33661 tatctaagcc agttctgtaa actactaata tttgaaatcc acttcctttt agggtacaat
    33721 ggttataaat gaatttttga gaggatcaga atgaaaaaac tagcaaccct tcttttactg
    33781 tctactgtag ccctagctgg gtgtagcagc gtccaacgca gtctgcgtgg tgatgattat
    33841 gttgattcca gtcttgctgc tgaagaaagt tccaaagtag ctgcccaatc tgccaaggag
    33901 ttaaacgatg ctttaacaaa cgaaaacgcc aatttcccac aactatctaa ggaagttgct
    33961 gaagatgaag ccgaagtgat tctccacaca agccaaggtg atattcgcat taaactcttc
    34021 cctaaactcg ctcctctagc ggttgaaaat ttcctcactc acgccaaaga aggctactat
    34081 aacggtatta ccttccaccg tgtcatcgat ggctttatgg tccaaactgg agatccaaaa
    34141 gggaacggta caggtggtca gtccatctgg catgacaagg ataagactaa agacaaagga
    34201 actggtttca agaacgagat tactccttat ttgtataaca tccgtggtgc tcttgctatg
    34261 gctaatactg gtcaaccaaa caccaatggc agccagttct tcatcaacca aaactctaca
    34321 gatacctctt ctaaactccc tacaagcaag tatccacaga aaattatcga agcctacaaa
    34381 gaaggtggaa accctagtct agatggcaaa cacccagtct ttggtcaagt gattgacggt
    34441 atggatgttg tggataagat tgctaaggcc gaaaaagatg aaaaagacaa gccaactact
    34501 gctatcacaa tcgacagcat cgaagtggtg aaagactacg attttaaatc ttaaaaacca
    34561 aaaaaataca gtatccacat tcggtactgt atttctttta ctctcattct taagttaaat
    34621 tattaaaatc ccatatttgg tctatccagc cttcataaaa gtctggctcg tggcagacca
    34681 taaggataga tcccctatat tctttgagag cgcgtttgag ctcatccttt gcatccacat
    34741 ccaaatggtt ggtcggctcg tccagcacta aaacgttgtt ttcacgattc atcaagagac
    34801 agaaacgaac cttggcttgc tctccccctg ataatacttg aatctggctt tcaatatgtt
    34861 tggttgtcaa accacaacgg gcaagggctg cacggacttc tgcttgatta agggcaggaa
    34921 aggcattcca gacagcttca agaggagttt ggcgattacc gccttctact tcctgctcaa
    34981 aataaccaag ttctaaataa tctccacgct ccacttcccc agcgattggc gagataatgc
    35041 ctaagagact cttcaagaga gttgtttttc caataccatt agcaccaata atcgcaacct
    35101 tttgattgcg ttcgaaggta agatttaaag gcttagtaag aggacggtcg taaccaattt
    35161 gcaagttctt ggcttggaag ataaagcgcc ctggtgtacg agctggtttg aaatcaaagg
    35221 atggttttgg tttctcactt tggagttcga taatatccat cttatccaat ttcttttgac
    35281 gagacatagc catattacga gttgcaacac gggctttatt acgagccaca aagtccttga
    35341 ggtctgcaat ctctttctgc tggcgttcgt aggctgcctc tagctgagat ttcttcatag
    35401 cataaacttc ttggaactgg tagtagtcac cagagtaacg cgtcagctgt tgattttcca
    35461 catgatagac aatattaata acgtcattga ggaatggaat atcgtgcgaa atgagaacaa
    35521 aggcattctc atagttttgg agatagcgct tgagccaatc aatatgctca gcatccaagt
    35581 agttggtcgg ctcgtccaac agcaagatat caggcttttc aaggagaagt tttgccaaaa
    35641 gcaccttggt tctttgccca cctgacaaag aagttacatc cgtatccatg ccaaagtcca
    35701 taacaccaag agcacgcgct acttcgtcaa tcttagcatc caaggtatag aaatcacgac
    35761 tctccagacg gtcttgaagt tctcctactt cttccatgag agcatcaaca tccgcgccgt
    35821 cttcagccat tttcatatag aggtcattga tacgagcttc agctttaaaa agctcatcaa
    35881 aagccgtacg gagaacatca cgcaccgact gtctttcagc aaggacagag tgctgatcca
    35941 agtaaccagc cgtcacatat ttggaccact caacctttcc ttcatctggc agcattttac
    36001 cagtcacgat actcataaag gttgattttc cttcaccatt ggcaccgacc aggccgatat
    36061 gttctccctt gaggagacgg aaggacacat cttcaaaaat tgcacggtca ccaaaaccgt
    36121 gactcagatt tttaacttct aaaatactca ttttaattcc ttatcttgtt tttatgtaat
    36181 cgtttataaa ggagccaagc cagatagcca cccaaagtgt tggtccacaa atcatcaatc
    36241 tcaaagacgc gattgaaatc aaagaaaaag tccaagatta attgcgtaca ctcgattcca
    36301 agactcacaa gaaaactaaa aagaaggacc ttttttgttt tccgcaaatt tggaaataga
    36361 taaaggagtt ggaaaatcag aggaaaaaac aagaagacat tgaggacatt ttgtaaaaaa
    36421 atccaacata attgtccaat gtcactcact tcgcccagtt tccagagaga attgaaagga
    36481 gtcaaaagaa aaaccaggcg tccaagatgc tgaatacctg gagttcccac tcccacggta
    36541 gattgttctt gaggagtaaa gcaaaaacag acaatgcaaa tgctatagaa aatgactccc
    36601 cagaccaaaa tatgattata agtcttcttc atcattaagg atttaccgct gcgactgcct
    36661 tctggcggtc acgtttcatt gtgttagagc gcaattgtcc acaagctgcg tcaatatctg
    36721 taccatgctc ttgacgaacc acacagttga cccctttttt cttaagcgta tcatagaaag
    36781 ccaacacgcg ctctttggga ctacggctat attggtcatg ctcactaact gggttataag
    36841 gaatcaagtt tacataagac aatttcttga tgttcttgag caattcagtc aattccaagg
    36901 cttgttctac actgtcgttg acttcattaa gcatgatata ttcaaaggtt acacgacggt
    36961 ttgttgtctc aatgtagtat tcaatagcag caaagagttt ttcaatcgga aaggcacggt
    37021 taatcttcat gatacttgaa cgaagttcat tgttaggtgc gtgaagagac acggcaagat
    37081 tgacctgaac cccttcatca gcaaagtcac gaattttatg agccaaacct aaggttgaaa
    37141 ccgtgatgtg acgagcaccg atagtcattc ctttatcatc attgatagta cgaaagaaat
    37201 tcaagacatt gttgtaatta tcaaagggct caccgattcc catgacaacg atatggctga
    37261 cgcgttcatc ctgaccacgc tcatcaaagt atttctgaac cagcatgatt tgcgctacga
    37321 tttcaccgtt attgaggtca cgttgcttct taatcaaacc agaggcacag aaggtacaac
    37381 cgatattaca gccgacctga gtggtcacac agacagataa accatagtgt tgacgcatga
    37441 gtacagtctc aattaacata ccgtcgggca attcaaagag atatttgact gtaccatcag
    37501 cagactcttg cacaatacgt tgtttcaagg gattgaccac aaactggtca ttgagcttag
    37561 caatcaaatc cttggaaagg ttggtcattt cttcaaatga ctgcacacgt ttacggtaga
    37621 gccattccca gatttgatct gcacggaatt tcttttctcc ctgctccaat acccattcct
    37681 gcatggtttg atgtgccaaa ctatgaattg agggtttcat ttcttctcct tattctctac
    37741 tcacttctga cgaatgacaa aatgacgttg tcccttgtcc tctttctgag aatgctggtc
    37801 tttctgacga cgtctattct tcttatctgc attcgacttt cgtttagttt gagtcggttt
    37861 ctttcctttt ctagaaggtg tttcttcttc cgtcttacgc attttcttgt caaatgatgc
    37921 tcgcttaggg gcttcatttt ctaagacaaa ataggcacaa ccataactac aatactctaa
    37981 aaggtagtct tgtaaacgac tgattttttc aagtttttct tctgttcggt catccttgta
    38041 aaaacctcgt aggcgaagct gttcgttgct ccagtccccc acgatataat caaacttggt
    38101 taatacttct gaaaaacgct gattaaaagt cgtcacatca aaggcatcct tgatattttc
    38161 aaccaaggaa aaagctatcc cttccgtttc gaccttgtcc ccgtgtaaat ggaactccgg
    38221 accaggaaac ttgttatagt tgtataattc aggtgcaatt tcttttcgca tagatatcct
    38281 ttttccacga ttacttaata ctttattcta ccataatttc tagcagttag cacgtttctc
    38341 ataaaaatga aaaaagtctg acgattttgt cagaccagaa tcttataacc taaaaagaga
    38401 agaacaattc ttccctccaa ctatcattat ttagcagctg cgtacaattc atctacttta
    38461 ttccagttga ttactgaaaa gaaagctttg atgtagtcag gacgcacgtt gcggtatttc
    38521 acgtagtaag catgttccca aacgtccaag cccaagattg gttttttacc ttctgagatt
    38581 ggtgtgtctt ggtttgctgt tgaagtcact tcaagtttcc cttctttgtt gacaaccaac
    38641 catgcccaac ctgaaccaaa acgagttgtt gctgctgcag tgaaggctgc ttggaattct
    38701 tcaaatgaac caaatgttgc atcgattgct gctgccagtt ctgctgaagg agctgttttc
    38761 tcgggagtca tcaattccca gaaaagagcg tggttcaagt gtccgccacc attgttgata
    38821 agtgcttgac ggatatcagc tgggatagat tctacatcag caagcaaggc ttcaaggtct
    38881 tcaccgattt cagggtgttt ttctaaagct gcattggcat tgttgacata agtttgatgg
    38941 tgtttgtcat ggtgcaaatg cattgtttcc gcatcgatgt atggttccaa agcgtcgtat
    39001 gcatatggaa gttctggtaa gataatagcc atctgtaata cctctttttc tttctatatg
    39061 aaaatgataa cgcaaacatt cacttttttc aagttttttg cttatagata aggaaatcac
    39121 tgacatactt tctaataaaa taagcaaatc agcaagaaac ccacgacaag ataatcctga
    39181 cgcgggttgt agtttcaaca aatgtcaatt gacctgacta gcaatctgta agagtgcctt
    39241 ttcaaaaagg aaaccttttt cataaagacc tgtcttaatc tgatagtctg tctcaatcaa
    39301 ataggaaata gcttgcttca gaaagctcaa agaaagtcct ctcgaatctc ttaatgcaaa
    39361 cttgatttga taaggatttg ggttacgtcc cagataacta cctaaactac ttgcaatctg
    39421 cgattctgtt tggccagact ccgccaaaat cttcacctga gtaaaagtcc gaaattgtcc
    39481 cagcatgact gcaatcagtt tgatttcatc ttccccttgc aaggtcaagt ctctcaccaa
    39541 atcgcgcgcc tgatccatct ttttagtcag aataaactga gttaaatcaa aaatattgtc
    39601 ctgcaaggtc ttgggaattg cgttaacaat atcctcttcc tcgataacag aatccgcctt
    39661 ataggactgt aaaaagagaa gatttttctg gatttcgcta aattgaaacc ccgacttgat
    39721 gaggagattt tcaaaagaat gattggtaaa ctgcagacct tgtttctgac tccacttttg
    39781 gaaatactgg cgcaattctt gttcttttac ttctactgca tcgaagacct tggcatcacg
    39841 cttaagtaat ttgactaacc gtcttttgct atccagcttt ccttctgcaa agattatcaa
    39901 cttggttgtt ggagaaggat tgtcaaggta ttcctcaaat gacttaagct catcatctgt
    39961 caaaaagcgt ttcttagcag tcgtgatatc cataaaataa tctaatatca cgattttctc
    40021 atccgcaaag aaaggaaggc tgaccaactc cagttccaca tccttgtaaa ctacttcttt
    40081 catatcaaag taggcaaagt tgaggtcagc agaatcatac ccaatctgtt tcaacacttg
    40141 actcttcatc acttcaaact gaccctgatc tgtccctgta aataggctca ggctcggtaa
    40201 atttgataaa gtcaacttct gactttcttc aatggctagc atcgtctctc ctttcttcag
    40261 atttttcgat ttaatttagt caatatagcg caatttccca cggaaatctt ctaagctctc
    40321 gtagcctttt tccaccatga ttgctttcag ttcattggta atgcggtcaa aagcactgac
    40381 gccttctttg tgaagggtcg ttcccacctg caccatactt gctccacaga ggatgtgttc
    40441 aaaggcatct cgaccagtca gaacgccacc tgttccgata atttggattt gaggatttaa
    40501 acgttgataa aaggcgtgaa cattggctag agcagtcggt ttgatgtatt ctccaccaat
    40561 tccaccaaaa ccattcttag gccgaataac gacagattcg tcttctatat agaggccgtt
    40621 tccgatagag ttaacgcagt tgacaaactt gagcggatat ttgttgaaaa tagctgccgc
    40681 ttgatcaaag tgaacaatat caaaataagg tggcaattta attccaagag gtttggtgaa
    40741 gtaagcaaac acttctgcca aaatccggtc tgttgtctca aaatcatagg caatctgagg
    40801 tttacctgga acatttggac aggaaagatt tagctcagtc agaccacgaa aatcactctc
    40861 ttggactttt ttcaaaatag tatgggtttc ctctggagac atgccgacca gagataagaa
    40921 gaaagttcgg ttcgactctt tttcctgcaa atctaaaaga taatccaaat aatagtctaa
    40981 gccattattt ggcaagccca tagagttgat ggaaccaagt ggaacatctt ggtagcgtgg
    41041 ctcaggattc ccctgacgga agtccaaggt cgctgtctta gtaacaaagg ttcctgccgc
    41101 tgagtttttg acctcttcta actcctctat cgtcatacaa gccacacctg ctgcattcat
    41161 caagcaattg tcaaactcaa aaccagcaat ttgtgttttc gttgatacca tgattctaat
    41221 cctccagatt tcttttattg ctaatattat accataattt taattctagg tttactagat
    41281 tctgtggttc tatctattta ttcggaaaag aaagtctagt acagaagtca tgctatggaa
    41341 acagctagtg tattagaagt ttgaacaagg cttgggtaac agacttttga atgaagtcca
    41401 agcaacaagg agaaatctca accatgagtc cattccatga ctctgttgct ctagaaaacc
    41461 ttgcaatagt caagtgataa cgaataaaac tttggattga aatatcccca agattatcta
    41521 ttacgaggag aaatcttaac ctttatcatt tttaaagaaa tatagtaaaa tgaaacaaga
    41581 acaggagaaa tcgatcagga cagtcaaatt gattgctaac aatgttttag aagttgaggt
    41641 gtactattct agtttcaatc tactatacat gtaaatctct actttcgcaa aatggatttt
    41701 cagaacagta tcccagtata gttaaaaact ataaaaaaga gaggacgttc ccctcttaaa
    41761 atcttatttt actgcttctt tcaaagcatc taccttatcc aaacgttccc atggaagatc
    41821 aatatctgta cgtcccatgt gaccgtaagc cgatgtttga cggtaaattg gacgcttgag
    41881 gtccagcatt tggataatcc ctgcagggcg aaggtcaaag atttgacgag ccgctttttc
    41941 aagttgactt tcagctactg ttcctgtacc gaaagtatcg atacgaacag aaacaggttg
    42001 cgcaacaccg atagcatagg ccaactgcac ttctgccttc ttagcaaggc ctgctgcaac
    42061 gatattcttg gcaatatagc gagccgcata agaggctgaa cgatccacct tagtcgcatc
    42121 tttaccagag aaggcaccac caccatgacg agagtagcca ccataagtat ctacaataat
    42181 cttacgacca gtcaaacctg agtccccttg aggaccaccg attacaaaac gacctgtcgg
    42241 attgataaag aattttgtct tatcatcaag ataagaagat ggaataactt ctttgatgac
    42301 cttgtcaatc acatcttgat ggatttgttc attagtggcc tctggatcat gctgagtaga
    42361 aataacgact gtatctacac gtaccggacg gtcattttca tcgtactcaa ctgtaacttg
    42421 tgattttgca tctggacgga gatagctaat ttctccagac ttacgaagtt ctgccagacg
    42481 acgaaccaat ttatgactga gtgcaattgg caatggcata agctcttctg tttcatctac
    42541 tgcaaatcca aacatgagcc cttggtcacc tgctccaatc aagtccagtg gatcttgatc
    42601 agcatttcca cgaacctcca aggcttcgtt aacaccttga gcgatgtcag gagattgttc
    42661 caccaaagat gggtgtactc ccaccgtctc agcagaaaat ccatattctg tattggtata
    42721 accaatctct gcaatggtat cacgaaccac acggttaata tccacatagg catttgtaga
    42781 aatttcacca aaaacgtgga cagaaccagt atatacagct gtttcagcag caacgtgcgc
    42841 ctctggatcc tttgctaaaa tagcatccaa aatcgcatct gaaatttggt ctgcaatctt
    42901 atccggatgc ccctcagata cagattcaga cgtgaataat ttacgttctg acataaaaat
    42961 gtcccccctt aaaaaatatt gttatagagt tacaaagtac tgataggaaa actcttcgta
    43021 ataaatacct accatcttat cgggactata taactttatc attataccat ttttaatcgc
    43081 aatttgcagt ctttaatgta gtgtttcggt ttagatagtt cgttctcata aagcaaaaag
    43141 ttggagctca gtactccaac aatttctatt aaaatgtttg acgtttagct ttacgctctg
    43201 cacgaccgcg agcgcgattt tcagcacgct tggttttacg gcgcttttca tcaaccgccc
    43261 attgaatttt cttcttataa cccggtttga cttttttctt tttcttttta accaaaccaa
    43321 tcatttcgat atcaagttta tcttgttttt tctcacggtt ggcacgacga tcacggtcat
    43381 aggtatcttg aaattccccg tctttgacca tcttaggact aaacttgatt cccaatttct
    43441 ccaactcacg gatatccgag tcatcacttg gctgataaag ggtaatagct gtacctggta
    43501 ggccatttcg tccagtacga ccaacacggt gaacaaaaaa agataagtct tgcggaatgg
    43561 catcattgat gacatggctg acaccttcaa tgtcaatccc acgtgctgcc aaatctgttg
    43621 cgacaatata ctcaaaatcc agattttgca cctgattcat gattcgcttg cgttcacgag
    43681 gggcaatatc gccatggatt tttgcaacct tcaagccttg agcagtcaga tatgaatgca
    43741 attcatcagc acgcgtttta gtgttaacaa aaatcattgc caaatacggc tgcatcaact
    43801 gagtcaactg gtaaatttga gcattcttat catgtccctt ggtcgaaatc aaccaattat
    43861 caatggtgtc agaaataacc gttttggtct taattttctc cataacagga ttggataagt
    43921 attttttcaa gaatggttgc agtttttgtg ggatagtcgc tgagaagacc atgaattgca
    43981 agtcttttgg aagactgcca gcaatcttat caacagtttc caagaatccc atatccaagg
    44041 tcatatccgc ttcatcaaca acaaatgtct tggctttatg aatagctaaa tcaccagatt
    44101 taaccaagtc gtagatacgg cctggtgttc caataacaat atgaggctga ttgcttgcca
    44161 atttctcaat ctggcgagcc ttatccgtac cacccacata attaaccaca cgaacttcga
    44221 catctgagtg agctgaaatc tgacgcgcta cttggtaaat ttgagtagcc aactcacgac
    44281 tcggtgcagt aatcactgct tgtacactat cgctagcttc atctaattgc tggaaaatcg
    44341 gtaacaagaa agtatgagtc ttacctgaac ctgtttttga ttctcctact aggtcacgac
    44401 ctgccaaaac aataggaatc aacttatctt gcacctctgt tggagttgta aattttaact
    44461 cctccaaggc ttctctaata tagtttttaa attgaaattt cgtaaatgac ataacatcct
    44521 cgattctatc tatcttatca attataccat attttattcc attacagtag tctcacttat
    44581 ttaggctatt tccagtagct tctctagtaa gaaaaggctg gaattttata ccccaattat
    44641 tcacccctaa tctaaaaa
//
LOCUS       DAVIME010000012        43682 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVIME010000012 DAVIME010000000
VERSION     DAVIME010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43682
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.012"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(141..1121)
                     /locus_tag="VV588_000704"
     CDS             complement(141..1121)
                     /locus_tag="VV588_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU7083080.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1437..3452)
                     /gene="recG"
                     /locus_tag="VV588_000705"
     CDS             complement(1437..3452)
                     /gene="recG"
                     /locus_tag="VV588_000705"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU7083081.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3471..4574)
                     /locus_tag="VV588_000706"
     CDS             complement(3471..4574)
                     /locus_tag="VV588_000706"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU7083082.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4564..4932)
                     /locus_tag="VV588_000707"
     CDS             complement(4564..4932)
                     /locus_tag="VV588_000707"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU7083083.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(4971..6002)
                     /locus_tag="VV588_000708"
     CDS             complement(4971..6002)
                     /locus_tag="VV588_000708"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU7083084.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMELENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEVFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6004..7035)
                     /locus_tag="VV588_000709"
     CDS             complement(6004..7035)
                     /locus_tag="VV588_000709"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU7083085.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7116..9629)
                     /gene="secA"
                     /locus_tag="VV588_000710"
     CDS             complement(7116..9629)
                     /gene="secA"
                     /locus_tag="VV588_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU7083086.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9775..10062)
                     /locus_tag="VV588_000711"
     CDS             complement(9775..10062)
                     /locus_tag="VV588_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083087.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLTFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10073..10723)
                     /locus_tag="VV588_000712"
     CDS             complement(10073..10723)
                     /locus_tag="VV588_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU7083088.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGNNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISKDISDLCTDVLAVENGHIQYVKDIQS"
     gene            complement(10727..11368)
                     /locus_tag="VV588_000713"
     CDS             complement(10727..11368)
                     /locus_tag="VV588_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083089.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11361..12152)
                     /locus_tag="VV588_000714"
     CDS             complement(11361..12152)
                     /locus_tag="VV588_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083090.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFLQIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12337..12672)
                     /locus_tag="VV588_000715"
     CDS             complement(12337..12672)
                     /locus_tag="VV588_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083091.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNVADIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(12812..13147)
                     /locus_tag="VV588_000716"
     CDS             complement(12812..13147)
                     /locus_tag="VV588_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083092.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13238..14548)
                     /gene="der"
                     /locus_tag="VV588_000717"
     CDS             complement(13238..14548)
                     /gene="der"
                     /locus_tag="VV588_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU7083093.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14562..15275)
                     /locus_tag="VV588_000718"
     CDS             complement(14562..15275)
                     /locus_tag="VV588_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU7083094.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15272..16168)
                     /gene="dnaI"
                     /locus_tag="VV588_000719"
     CDS             complement(15272..16168)
                     /gene="dnaI"
                     /locus_tag="VV588_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU7083095.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16169..17338)
                     /locus_tag="VV588_000720"
     CDS             complement(16169..17338)
                     /locus_tag="VV588_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU7083096.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLVLHAPLSSQD
                     FLEHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            complement(17339..17812)
                     /gene="nrdR"
                     /locus_tag="VV588_000721"
     CDS             complement(17339..17812)
                     /gene="nrdR"
                     /locus_tag="VV588_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU7083097.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            17952..18317
                     /locus_tag="VV588_000722"
     CDS             17952..18317
                     /locus_tag="VV588_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU7083098.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18322..19017
                     /locus_tag="VV588_000723"
     CDS             18322..19017
                     /locus_tag="VV588_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083099.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19034..19801
                     /locus_tag="VV588_000724"
     CDS             19034..19801
                     /locus_tag="VV588_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083100.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20154..21353)
                     /locus_tag="VV588_000725"
     CDS             complement(20154..21353)
                     /locus_tag="VV588_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083101.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21350..22243)
                     /locus_tag="VV588_000726"
     CDS             complement(21350..22243)
                     /locus_tag="VV588_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083102.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22359..22439
                     /locus_tag="VV588_000727"
                     /pseudo
     CDS             22359..22439
                     /locus_tag="VV588_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            22924..23137
                     /locus_tag="VV588_000728"
                     /pseudo
     CDS             22924..23137
                     /locus_tag="VV588_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23552..24169
                     /locus_tag="VV588_000729"
     CDS             23552..24169
                     /locus_tag="VV588_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU7083103.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24489..25376)
                     /locus_tag="VV588_000730"
     CDS             complement(24489..25376)
                     /locus_tag="VV588_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU7083104.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGENIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25525..27408)
                     /locus_tag="VV588_000731"
     CDS             complement(25525..27408)
                     /locus_tag="VV588_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU7083105.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            27785..29239
                     /locus_tag="VV588_000732"
     CDS             27785..29239
                     /locus_tag="VV588_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU7083106.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29220..30185
                     /locus_tag="VV588_000733"
     CDS             29220..30185
                     /locus_tag="VV588_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU7083107.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30220..31494)
                     /locus_tag="VV588_000734"
     CDS             complement(30220..31494)
                     /locus_tag="VV588_000734"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU7083108.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31494..32666)
                     /locus_tag="VV588_000735"
     CDS             complement(31494..32666)
                     /locus_tag="VV588_000735"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU7083109.1"
                     /translation="MTIGIDKIGFATSQCVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32797..33045)
                     /locus_tag="VV588_000736"
     CDS             complement(32797..33045)
                     /locus_tag="VV588_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083110.1"
                     /translation="MVSSWGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            complement(33113..33736)
                     /locus_tag="VV588_000737"
                     /pseudo
     CDS             complement(33113..33736)
                     /locus_tag="VV588_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(33798..34247)
                     /locus_tag="VV588_000738"
     CDS             complement(33798..34247)
                     /locus_tag="VV588_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU7083111.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(34249..35007)
                     /locus_tag="VV588_000739"
     CDS             complement(34249..35007)
                     /locus_tag="VV588_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU7083112.1"
                     /translation="MEESKELNTVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(35138..37117)
                     /gene="pknB"
                     /locus_tag="VV588_000740"
     CDS             complement(35138..37117)
                     /gene="pknB"
                     /locus_tag="VV588_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU7083113.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKTPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPIQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(37114..37854)
                     /locus_tag="VV588_000741"
     CDS             complement(37114..37854)
                     /locus_tag="VV588_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU7083114.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(37869..39182)
                     /gene="rsmB"
                     /locus_tag="VV588_000742"
     CDS             complement(37869..39182)
                     /gene="rsmB"
                     /locus_tag="VV588_000742"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU7083115.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(39175..40110)
                     /locus_tag="VV588_000743"
     CDS             complement(39175..40110)
                     /locus_tag="VV588_000743"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU7083116.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGCDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPKEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(40123..42519)
                     /locus_tag="VV588_000744"
     CDS             complement(40123..42519)
                     /locus_tag="VV588_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU7083117.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYRHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(42585..42899)
                     /locus_tag="VV588_000745"
     CDS             complement(42585..42899)
                     /locus_tag="VV588_000745"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU7083118.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(42924..43550)
                     /gene="gmk"
                     /locus_tag="VV588_000746"
     CDS             complement(42924..43550)
                     /gene="gmk"
                     /locus_tag="VV588_000746"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU7083119.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
BASE COUNT        12525 a         9920 c         8406 g        12831 t
ORIGIN      
        1 tgactgtcct gatcgatttg tcctattctt gtttcatttt actatatttc catgataaaa
       61 cgcatagtat caagtttttt taatcccctg atactatgcg tgtttgtaat ttttaagatt
      121 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      181 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      241 atacgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      301 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      361 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      421 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      481 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      541 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      601 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      661 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      721 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
      781 acatccatgg aaacaacacc ataaccagct acggtgaagc ccagcatgtc ggcccagtcc
      841 cagccacgtc ccatataacc atgaaaatgg aagattagtg gaaccttctc ctcactcttt
      901 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
      961 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aggtgtggaa
     1021 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1081 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1141 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga aggataaata
     1201 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1261 aaaagagcat ttcgctctct cttctgttta tactagtttt ttgcttcctt cttttggaaa
     1321 gtggtttggt aatttacttt aatcgttact gtcatatgag agtcctcgtt tctttttgat
     1381 gactttagta taagagccaa acctaaaaac tagcttaagt tttccttaga gaaagcttaa
     1441 tccagatgtt ctttcttttc cagatgaagg gcaatcatgc gccactctgg atcttcttgc
     1501 caagcttcta tagaactaat gtagctagca acctttcttg cttcttctaa aatcggaaaa
     1561 tcttcgataa tatcagccac ttggaactct ggaagtcctg actgtctggt tccaaaaatc
     1621 tcaccagaac cacgcatttt caaatcttcc tccgcaagga caaatccatt ggtcgtttct
     1681 gtcatgatgc gcatgcggtc tttcccagaa tccgtcttgg gattggcaac gagaacagcg
     1741 taggactgct tgtccccccg accgacacga cctctaagct ggtgaagttg actgagaccg
     1801 aagcgatcgg catccatgat aatcatgaca gtcgcattgg gaacgttgac cccaacctca
     1861 ataaccgtcg tcgaaaccag aatatccgtc tttctctcct tgaaatcctg catgatctgg
     1921 tctttttcgt cactcttcat cctaccatgt agaagagcca cctctgcctt gcctgcaaaa
     1981 tgagtcgtca actcctctga taaggcaatg gcatttttca aatctagagc ttctgattct
     2041 tcaatcaaag gagagatgac ataggcttgg gaaccttttt gaatttcccc ctctaaccaa
     2101 gtcaagacct gaggtagttg ctcatgtttg atccagcgcg tcacaatagg cttccgacct
     2161 gctggcatct ggtcgataat ggaaacatcc atatctccaa aggctgtgat ggcaagcgtc
     2221 cgtggaatgg gagtcgccgt catcatgagg acatctggat tgtcaccttt ttcccgtaaa
     2281 atacgccttt gccctacacc aaaacggtgc tgctcatcga taataatcaa accaagacga
     2341 gcatactcca ccccatcttg tatcagagcg tgagttccta taatcaaatc agcctcaccc
     2401 ttggcaatgg tctccaagac ttctctcttt tctgcagctt tcaaggaacc tgtcaagaga
     2461 gccagtttca aattgggaaa aaggttctgt aaactctcaa agtgttgctc tgcgaggatt
     2521 tctgttggta ccattagggc agcctgataa cctgctgtca ctgccgcaaa catggccaag
     2581 ccagcgacta ccgtttttcc actccccaca tctccttgta ggagacgatt catgtggtgg
     2641 tcggacttca tatcagttaa aatttcctgc aaactctttt cctgagcttg ggtcagggca
     2701 aaaggaagac ttgctttaac tgctgtcact ttttcctgag accaatccag aaccagacca
     2761 cttccctgaa ctctattttc agacttgagc gtctgcagct gcatttggaa ataaaagagt
     2821 tcctcaaact tgatacggcg aagagcctgc ttgtattctg ccaaatcctt tggaaaatgc
     2881 atagctcgga ctgcctgaca acgggacatg agtttgtatt tgtctagtaa agactggggc
     2941 agattttctt ctatcaagag gtccagtccc tgatcaaaag ccgtcttgat gaccttgacc
     3001 agactggcct gactgattcc ctgagccaga cgatagacag gctggaggtc atcttctacc
     3061 tgagccagaa ccttcatccc agtcagacta gccttagcgc ggtcccattt tccaaagaca
     3121 gcaagggttg ctcccaactc tattttatca gccagatagg gctggttaaa gaaattcacc
     3181 gcaaaaacga cctctccctg cttgagacta aaacgcaggc gattgcgctt gaaaccataa
     3241 tactggacac tagcaggagt cactacctga ccagaaagaa ctgccttctc accgtcttcc
     3301 agctccagca cctgcttggt tttgaagtct tcataacgga aaggaaagta gagcaagaga
     3361 tcttgcaagt tttcaattcc tagtttggcg tatttttctg ctgactttgg tcccacacca
     3421 ggcaagacat gcaagggttg atgtagattc atgctccact cctttctttt ctaataatat
     3481 tctctcggaa tacggtcgct gaggaggcaa accacctcat agttaatggt tacgcggtag
     3541 gtcgctacct gagttgcagt gatttcctta tccccattgg agccaatcaa ggttaccttg
     3601 gttcctagcg gataaagctt aggcaatcga atagtgattt ggtccatcga aaccctgccg
     3661 acaattgggc aagcttggcc atctaccaag acagagaaat tttgcatgtc tcttgtccat
     3721 ccatctgcat acccgattgg cacggtcgcg atgacttgct cgctatccgc ttgataagtt
     3781 gctccatagc ccatgcaagc tccagctgga actgtcttga catgaaccag agcagactcc
     3841 aaggtcaagg ccggtatcaa atcataaggc aaatccaaga ccgctccact tggattgagg
     3901 ccatacatgg catctcccat acgaaccgca ttgaaaatag tctctacatg ccaaagagtc
     3961 gttgcagaat tgctagcatg aaccagctct ggaacttcct tcatactagc taaaatagtt
     4021 ttaaaccgtt ctaactgggc attaaaatag tcatctgatt cctcatcagc agtagcaaag
     4081 tgggtaaaga ttccttcaac acgaacaccg tgttgttgta gcaaatcttg agcctgctca
     4141 acctcactgg cctctctaaa accaatccgt cccatccctg aatcaatctt gaggtggact
     4201 gtcaatccag ttaggtccac ttccttatct aagagtgctt gaatccactc cagtccagcc
     4261 actgtcaagg tgaagtcata ttctttagct agagcaacag cttcgatttc agaaactcct
     4321 aaaatgagga ttggcttgct gagtccagct tgtctgagtt caatggcttc atcgatattg
     4381 gaaacgcaaa agccatcaac atcatcttga attgccttgg caacggcaac agctccatga
     4441 ccataagcat tggccttgac cacagccaac ttgagcgttc cttgagggat atgagccccc
     4501 atttgctgaa tattttgtcg aatagctccc agatgaatca gagccttggt tggtctatgt
     4561 ggactagctt tcatgatttt cctccaaaat gacactggct gtcacaaact gatcggtgtg
     4621 gctgatagac agccaaatct ttcctgaaaa tggtgcctga ctaaaataag gcgccccacg
     4681 ttcattgttc aagacttcca aatcctgaaa accgagcttg ctaatgcccg ttcccatagc
     4741 cttggaaaag gcctccttag ccgaccagcg accagctaaa tattctattt gcctgcgtcc
     4801 tttgagactg gtgaagcgct ccatttcctg agcggtcagt acacgcttag caaatccttc
     4861 atgtcgtgta actgcgcttt ctatcgaagc caattcttcg atgtcaattc cgtgtccaac
     4921 tatcattctc atcaaaagga gttgagattc cccaactcca tccttttcac ttattttgtc
     4981 aaggtaacat aaatctcttc taccaaggcc tctgtatttt cccaacctag gcaagggtca
     5041 gtaatagagc aaccaaagac ctctggttgg ttttgacgac catctgctag gtaagattca
     5101 atcataaatc ctcgaaccgt ctttttaatt ttctcattcc aatcacgatt ctgcaaggtc
     5161 tggcgaacaa ttcgaatctg ctccatatat tgcttgcctg agttatcatg gttggtgtca
     5221 atgaggataa aaggattttc aagttccatg gtttcatagc gttcaatggc ttggagtagg
     5281 ttttcatagt agtaattcgg catataattg ccatactcgt tgactgctcc acggaggata
     5341 acatgggcca aaggattacc tgatgtctca acttcctgcc catgataaag gaaggtttgc
     5401 ttgttttgag cagcatagat ggcgttaaac ataacaccca aatttcctga ggttggattt
     5461 ttcatcccta ctggtgcatc aatcccagaa gccacaaagc ggtgctcttg gtcttccaca
     5521 gaacgagctc caacggcatg gtagctgacc aagtcatcca ccaagatcag atttgacgga
     5581 taaagcatct catctgccgt tgtcaaacca gtctctgtaa tcacgcggta gtgcaactgg
     5641 cgcacagcct gcaagccgtt aatcaggctt ggagccttag aagtatctgg ctggtgaacc
     5701 aatcctttat agccgtctcc attggtacga ggcttagcag tatacacgcg catgaccatg
     5761 aaaatcttgt ccgctacctt cttttgcaag gcggataaac ggcgagcata ttccaagacc
     5821 gcctcttcat tatcagaaga gcaaggacca atcaccaaga gaatacggtc atcttcccct
     5881 gaaataatat ctgccaattc cctgtcacgg ctttccttga gtctcaaggc ttccgcagac
     5941 aattgggttt cagccttgat gacttccata tcgatttctt gacctttttc aataaatgcc
     6001 atcttattct cctaacgttt tgtaaatttc tctgacaaga gcttctgtgt tatcccaacc
     6061 caggcaaggg tctgtgatag acttaccaaa tacttctggc tcattttgtc gaccatcttc
     6121 cagataagac tcaatcataa aaccacgaac gaactgctta attttttcat tccaagcacg
     6181 gttaatcaag gtctggcgga caattcggat ctgttcaata tactgcttac cagaattgtc
     6241 atgattggta tcaatgatga taaaaggatt ttccaagccc attttctcat actgggcaat
     6301 ggtatcaatt aaattgtcat aatagtagtt gggaatattt tttccatact cattaagagc
     6361 accacgaaga atagcgtgtg aaagcgggtt cccagttgtt tctacttctt ttcctaagaa
     6421 aaggaaactt tgtttgtttt gagcagcata aatcccatta aacatgacat tgagatttcc
     6481 agaggttgga tttttaaaac cagtagaaaa tcctgcccca cttgccacaa agcggtgttg
     6541 ctggtcttca actgaacggg caccaactgc catgtaagaa atcaaatcat ctacaagcgg
     6601 aaggttttca ggataaagca tttcatcagc agttgtcatc cctgtttctg tgatgacacg
     6661 atagtgaaga tggcgaacgg ctttgattcc attgataaga ctaggcgctt ctgtcgcgtt
     6721 aggctggtga atcaagccct tatagccatc tccgttggta cggggtttgg cagtataaac
     6781 acgcataacc ataaagatac gatctgccac ttcttcttgt aggactgcca aacgcttagc
     6841 gtattcaagg acagcttctt cgttgtcaga tgagcatggc ccgattacca agagaattcg
     6901 ctggtcttct ccacgtataa tggcttctag ctcttgatct cgctgtgatt tcctctccaa
     6961 agcctgacct tctaattttg acaaggcacg aacttcttct atatttattt tagagctttt
     7021 tgctgtaaat accataactc atctccttat aaagcaaacg gatacccagt aaaaatttac
     7081 ttttcacaag atatccgcct ctaaactatc tcattttatt gtcttttacc gtgacagttt
     7141 ttaaatttct taccagaacc acatgggcaa agttcattgc gtccaatctg gctcaaatcc
     7201 aaatcttctg gcatacttgc ttggtgagca gcgatattgc gagtcgctgt tgtactgata
     7261 tgacgttctg cctgtggtct ttcttgttca tgaatttgtg ctttcatcat caagcgtgtc
     7321 acatcaaact caatcgaacc aatcatatca ttaaacatac ggaaaccttc tgcctgatac
     7381 tcaacaacag ggttgttctg agcatagcca cgaagtccaa ccgcgttacg caattgatca
     7441 agggcatcga tatgatctgt ccacttgtta tccaccactc gtagaatcaa aactttttgg
     7501 aattctttaa ctgcttcttc atcgcgtagt tttgaaacct gactatcgta aaccttcaag
     7561 gcacgttgga aaagctcttc cttgatggcc ttatcagaca agcctgacaa gtcttccatc
     7621 gtaatagaat cttcaggaag caagttgtac ttagcaaagt tcaaaattgc ctctagtttt
     7681 tcatcttgtt tggcacgcgc atgaccatca acgacacgtt caatcgtgcg tttgatcata
     7741 gactgaattt caggtgccaa gtcacgatct gcagtgatga catcgtaacg ttgagcatag
     7801 ataatctcac gttgttcacg catgacatca tcgtattgaa ggacttgttt acgggtatcg
     7861 tagttatttc cttcgacacg tttctgagct gcttcaacct gacgcgtcaa catgcgagac
     7921 tcaatcgcct cttcagacat gttcaagcgt tcaaagattc ccttcaagcg ttcagaacca
     7981 aaacgtttca tcaaatcatc ttcaagagat aggtagaatt gtgactcacc tggatctcct
     8041 tgacgacctg aacgtccacg aagctggtta tcgatacgac gactttcatg acgttctgta
     8101 ccaataacac aaagtcctcc aagttcacga acaccttcac caagcttgat gtcggtacca
     8161 cgacccgcca tgttggttgc gatggtaacg gcaccacgtt gaccagcatt catgatgatt
     8221 tgggcttctc tatagtggtt tttggcattc aagacttcgt gaggaacacc agctgcaacc
     8281 aatttcttag aaatgtagtc actagtttca accgctactg taccaaccaa gacaggttga
     8341 cccttttggt aacgagcctt aacgtcttcg acaaccgctt taaacttaga ttctatactt
     8401 gcataaagaa ggtctgagtg gtcaatacgt tgaacaggac ggtttgttgg gattggaata
     8461 acacgaatgt tgtagatttc acggaattct tcttcctcag tcttacctgt acccgtcata
     8521 ccagacaatt tcttgtacat acggaaaagg ttttggtacg tgattgaggc agatgtcttg
     8581 gtttcatcct ggattggcac accttctttg gcttcaatag cttggtgcaa tccatcagaa
     8641 taacgacgac cttccatggt acgacctgta aattggtcga caatcaagat ttcttgctct
     8701 tcgctcacca catagtcaat atcgagaagc atgatgtagt tggcacgaag ggcgttatcg
     8761 ataaagtggg tcaaagccac gttttcgatg tcatagaggt tttcaagttt gaagtagctt
     8821 tcagccctgt caatccctga atcagacaaa ccaatagtct tagactgcac atcgatgatg
     8881 tagtcatctt tgttcaaaga ttttacatag tggtctgcca tgtgatacaa ctgactggtt
     8941 tcaaccgcat tggcacctga tacaatcaaa ggtgtacgag cctcgtcaat caagatagag
     9001 tcaacctcat cgaccaaggc atagttaagc ggacgttgta ccatgttttc agcgcgaacg
     9061 accatattgt cacgaaggta gtcaaatccg atttctgagt tagttgagta agtaatatca
     9121 cactcatagg cttctttttt ctccattgga gatttggtag ccaagttaat ccctactgac
     9181 aaaccaagcc aagagtacaa ttcacccatc tcagtcgcgt cacgttctga caggtattca
     9241 ttaaccgtaa ctacgtgaac ccctttacct gaaagggcat tgaggtatac cggcatggtc
     9301 gcagtcaagg ttttcccttc ccctgtacgc atctctggca cgtcaccatg gtgaagaaca
     9361 atccccccca tgacctgaac cttataaggg aagagaccta ggacacgttt ggcaccttca
     9421 cggacaaccg caaatgcttc gtaaagcaat gaatccagtg attctccatt ttgataacgt
     9481 tccttaaatt caactgtttt tgcttttagt tggtcgtcag tcaaagcagc catttggtct
     9541 tcgtatttga aaaccttgtc agccatcttt tccagacgac ggatttctcc tttatcattt
     9601 tcgataattg tttttaaaat attagccatg tttttcctta ctttaaattc cgaatatttt
     9661 agaatgttcc tttaatttta gcacaattac tgattatttt caaggaagaa tccccatttt
     9721 gaaaaggaaa aagaggttag ttttcaagct aacctctccg acttttatga tgctttaatt
     9781 gccaaaaatc ggcaaaatgg caaatgtgat aaataagtta atccaaagag aaagacagca
     9841 aatcagtcca aaaacaaaga gactgacttt cttggacagc aaggccatca aaatggacag
     9901 aattccaaaa gctagcaaga ttttctgtat gatgaagatg tcaatcctta cccccagaat
     9961 cgctctatcc caagggataa agaagaaagt cagccagatc agcagaacta aaccaatata
    10021 aaccttggaa tagcgtgtaa taaatgattt tagatgtgcc ataagccatc tcctaggatt
    10081 gtatatcctt tacatattgt atatgtccat tttcgacagc taatacatct gtacaaaggt
    10141 ctgaaatatc tttcgatatg tgcgacgtca ggataaccag accattttct tttttcaggt
    10201 aagataaaat gacctgtttg gttaacctca cactcttctc atccaaagca ttcataggtt
    10261 catcgagaaa gagtatagaa ggagaggaaa taaaggcttg aatcaaggcc attttttgct
    10321 ttgttcccaa ggataaatga cggtattcaa cgtcttcaaa ttcctgtaaa tcatagtatt
    10381 gaatccaata ggcaattctt ttttccgtaa ctttagatga aaaatacctt aacagttcca
    10441 aattttctct cagggataaa tgagataaaa actcgacttt ttcaattaaa attcctgcat
    10501 cctgaatata atgatttttt accccgtaaa ctttaccatc ttgaagaact tttcctttgt
    10561 caagcttaat ataaccagca agtatcttta aaagaaccgt cttgccagat ccattattac
    10621 ctttaagtcc ataaattttt cctgattgaa acaccaaatt caactgattt aaaataggtc
    10681 ttttcccata aattttctgt ccatttataa tttcaagtct catcgtttat cctttcttaa
    10741 atttctcttc caagcgacta agaatcaaca taactaataa gcttaagagt actaaataca
    10801 ctgttacaat atgatccatc atccattctt gtcccacaaa tgccaaaaaa tagagaaaaa
    10861 aagaaaaacc agcgcccgca ctaatcagtg ctatcagata agacagtagt aagtacaaca
    10921 tcattaactg agcaagtaaa aagaaaagtg cgactgtttt gaaatgaatt cctagaggaa
    10981 gtaaaccaag aaaccagaca aacaaatctt gagtaaaaaa tttagaaatg acaaccaatc
    11041 gtttccttgt ataatcgaaa aaggagcttg attgatagcg aatcaagtga tggtaatggt
    11101 ctgccaaatc actttcaagt aaaatgacag agagccatcc taccatgaaa agcgaaaggt
    11161 ttaacaagag tttggggatt tctaaattca cttcagaata gtcattatag gaaaaaattg
    11221 aaatcaattc tctcttgaaa aagataacag catcctgctt ttgaaccgct gttgacaata
    11281 gatggtttat caaaatcatc atcagaacta tacgaagtag taaaacaatc tttctcttta
    11341 gcaaaatatt gttaaaattc ttaaacatta tcttcatatt tttcaagcac catgtaaggg
    11401 acaatataaa ggatataagg agtaaagagt ttcatcaaac ttacatcccc atagctagct
    11461 tgcatcaaac tcgtcatagg aaccatatag taaggcaagg cactatagag cagcatagaa
    11521 ccaagccaaa gaaacatcaa ataggtgatt gccgaacgag tcacatttcc taaataatca
    11581 actatttgta aaaaatagac tgcattgatg aaaataccga ttagtaggac acaagtaaag
    11641 aacaaatagc ttgttatctc tccatctagg agcctttgta aactactccc atcagaaaat
    11701 agagaattcc atccaagagg agaaaaagtc ccaaagaaat gagttaaaat tgcaattatc
    11761 agcacagtca ctaaatatat caaacaaggg atacttgcaa cttgcaaagt caactttctt
    11821 tttaaccctt gataactcac ttctcttcca atactcaatc gtaaaacttt atttttcagc
    11881 tcaatatatt gaaaacctag caaaacaatg atgattggaa taataaatga ttgataaaaa
    11941 cctagattga actggagaat acgaaaatct aatgctgatt ttaataagtc atttttaatt
    12001 gcttgtccat cgaatttagc tagatcgggc gcatgaatat caaaaaagaa ataagtcatc
    12061 aaaacatcac gataaaccaa agcaagaaaa agcaaagtaa gcaagacata aacaaattta
    12121 tgccttgcca aagttaagag aggaatcttc ataagccacc tcctacaaat agaaagtaat
    12181 ataatactca atgaaaatca aagagcaaac taggaaacta gccgcaagtt gctcaaagca
    12241 ctgctttgag gttgtagata agactgacga agtcagttac atatataatc caaggcgacg
    12301 ttgacgtggt ttgaagagat tttcgaagag tataaatcaa tgccttccgc ctttagactt
    12361 ccctagttcc cgtctcaagt caagcatttt tttgaaacag atatagtcta accagtcact
    12421 agcaaaagcg ataagtagta ataatagcca aataccccat aacttgatgt ctgccacatt
    12481 tctcaagacg atattgaaaa acagaactga aaaaactgtc caagcaaggc taaaaagagc
    12541 atagagggtg atgtaaatcc agtaaaaata gtaaaaaatt gggaaaaatt tactttctct
    12601 attatccttg tcaatccagc tgaaaaagta aaaacagggt aataagatta tcattttaaa
    12661 caagtgttcc atcacaagcc tcctttttta aattgttttc tttagtttcg ttctattaaa
    12721 tgttattacc aatataaacc ttggaatagc gtgtaataaa tgattttaga ggtaccataa
    12781 gccacctcct acaaatagaa accgatataa atcaatgcct tccaccctta gacttcccta
    12841 gttcctgtct caagcgaaac atttctttga aacaggaata agttaaccaa ttcataccaa
    12901 tagctagcag aataaaaaga aaccaaatgc cccataactt gatatctgtc acatttctca
    12961 agacggtatt gaaaaacaga actgaaacaa ctgtccaagc aaggctaaaa agagaataga
    13021 aggggatgta aaaccagtaa aaataataaa aaattggaaa aaacttacta tttctgttgg
    13081 ccttctcaat ccagttatca aaataaaagt acggtgctaa aagtaagaat ttaaacaaat
    13141 gttccatcac cgacatcacc ctccttcttt tgatagcgtt ttctattatt ttattatatc
    13201 aaaaaaatcc ggaactgtca ttccagattc tactttttta tttgcgtttt cttgcgatga
    13261 gatgaatcgg tgttccctca aaaacaaagg ccttgcggat ttgattttcc aagaaacgca
    13321 ggtaagaaaa gtgcatgagt tcttcttcat tgacaaagat gacaaaggtt ggtggtttgg
    13381 ttgccacttg ggtcgcatag aaaatcttga gacgttttcc tttgtctgtc ggtgttgggt
    13441 tgatggcaat ggcatccatg atgacatcgt tcaagacagc tgatggaata cgtgtatttt
    13501 gactttcgct gatttgctta atcatctcag gaagtttgtg gagacgttgc ttggttaaag
    13561 ctgatacaaa gataatcggt gcgtaaggca ggtattggaa ctgctcacgg atatcttctt
    13621 cccagttttt catagtgtgg ttatcttttt caagcgtatc ccacttgttg accacgataa
    13681 tcatcccttt accagcttca tgggcaaatc ctgcgatacg cttgtcgtac tcacgaatgc
    13741 cttcttccgc attgatgacc atcaagacca catctgaacg gtcaatagca cgcatggcac
    13801 gcataacaga gtatttctca gtattttcat aaaccttacc agacttacgc ataccagccg
    13861 tatcaatcat ggtaaactct tgaccatctg tatctgtaaa gtgggtatca atggcatcac
    13921 gagttgttcc agcaacagga ctagcaataa cacggtcttc tcccaagata gcattgatca
    13981 agcttgattt tccaacgtta ggacgaccaa tcaagctaaa cttaatgaca tctggatttt
    14041 cttcctcata ttcatttgga agattttcta cgatcgcatc tagcacatcc cctgtaccga
    14101 ttccatggac agatgagata ggcaatggtt cacccaaacc gagagcatag aaatcataga
    14161 tatcatttct catctcaggg ttgtccacct tgttgactgc gaggataact ggtttgtggg
    14221 tcttataaag cttacgagct acgtattcgt ctgcatcagt aattccttcc ttaccagaca
    14281 cgacaaaaac gataacatct gcttcttcca tggcaatttc tgcctggtgc ttgatttgtt
    14341 ccatgaaagg agcatcgaca tcatcaattc ctcctgtatc aatcatgcta aaagaacgat
    14401 tgagccactc acccgttgca taaatacggt cacgtgtcac tccttcgaca tcttctacaa
    14461 tggagattcg ctcaccagcg atccgattaa atagggttga tttcccaaca ttgggacgtc
    14521 ctacaatggc aatagttggt agggccataa tttctcactt tctacaataa tttcttctgt
    14581 tcaagatttt ttctagttga gcttggttca gcttgaccaa actgttctgc taggcgctga
    14641 ctccagcttg tggtcgcacg cgccccagca tagtcagcct gaacacggtc ataagcttgg
    14701 attgcctcag ttgactgttc ttggtattct tcctcaaaga caacattctc tagtggcagt
    14761 cttggtttca tatcatgatg ttgatttggc acacccagtg ccatcccaaa gacagaatag
    14821 gtgtagtcag gtaggttaaa gagctctgcc acttcttcag acttgtatcg aaccaaaccg
    14881 ataatcacac caccatagcc caagctttca gctgccaaca aggcgttttg tccagcaaga
    14941 gctgcatcga ccgaactaat caagagacct tccacacctt ggggttggaa ggtgtcggta
    15001 tgaagtcggg ctcccttttc tgctcggttc aaatctccga caaagagaag gaaaacagca
    15061 gactggcgaa tggcttcttg aggtaccaat tcatacaagg catctttctt ctcttgactt
    15121 cgtaccacaa tcacagagta ggattggaaa ttcttccaag atgatgccat ctgggctgct
    15181 gtcaaaatct catttaagtc tacttgggga atttcttgct ctttaaacct gcgcactgaa
    15241 gtatgagcct tcatcaattt aatggtttct gtcatcgacg gtttactcct tctaaacgag
    15301 tctcctcagc caaataacgg atgcgttcca tgacccgtct ggcttcccag gtttcgtcat
    15361 ttccatgttt cactttcgca aaatgcttct ccaaatcttc aaagttgaag ttggatgtga
    15421 aaaaggtcgg taaattttcc tgcatccgat attggagaat gacctgcagg atttcgtcac
    15481 gcacccaaac ggttgattgc tcggcgccaa tatcatctaa aatcaggacc tcagacagct
    15541 taatctcatc caccaaggtc ttaacattgc catcactgat agcatttttg acatcaatga
    15601 caaagctagg atagtggagg agagtggatg atacaccacg tttttctgat aaatcatgag
    15661 ctagggcagc caccatgaaa cttttaccca caccaaagtc tccatacaag taaagacctt
    15721 tcaaattatt ggggtaatcg ttaacaaatt ctatcattct ttttagaaca gttaagcgct
    15781 gaacatcatc acgataaaca tctaaaaaac tgacattttt caggctagat ggaaaattaa
    15841 ttaagttgag acgtttcttg atagccgctt ctttttcagc tgcgattagt tcaggagttt
    15901 cttcataaga aacatctgca tagccatggt tcatgactaa tataggcttg tagcctttgg
    15961 caatataatc tgtatctcct cggaggaatt tatctctctc agtgatgtat tggttaaact
    16021 tggaaatact acggttcaac tcgtcctgat tgagggattc ttgctggaca aaggccgcaa
    16081 catcaggatc cttcatgatt ttctgaacta aatcttgata gtgaaaacga cttggttgac
    16141 gtttgagtac atctccgaca ctttccatct aatcacctcc gttatctaat tttgctaata
    16201 attctagggt ttggcgttcc atctcttcta attcctcagc ggatgacgta tttttatatt
    16261 caggattact ccatttagga atattggttt ttgctggggc agtctgattc tgtttttgtg
    16321 tttttgcttt ctgttctcgc tcacggatgc gcaagactgc cttttctgcc gaatgaatct
    16381 tttgataggc atagtcattg gctaccttca tggcatattt ctcattgata tttgccgaat
    16441 cgaccttatt aaaggtcaat aaaagaatga tattgatgac ttcgtccagc aagcccaagc
    16501 cagccatctg ttgcaagagt tctctttctg tttgggtaat ggttcccttg cgtgtttgct
    16561 tgatttctgc caagaactgc agggcagttt tacttttggc ttctttgata atggttgttt
    16621 ccttaagact aaagtcagag gaaactggtt tttgagcaat tttttcccgc atgcgtttgg
    16681 ttgaaataac ctgagaaaca gctgttgact tggccaattg ataggtttca aaccaagtcc
    16741 atttcttctc ctcggcaata gcaaagaggt ttaagacatc ggactgctca tccgcaaaac
    16801 gaagtccatc tcgagccatc agctggcgaa aatggtccaa gtcaaaatcg ttggccactt
    16861 tcttcttgag accaaggtct tcttgactgc ctagttctgc caattctgga aagacttgat
    16921 tgagtgagac aggtatttct tcaccatcag cactttcaac tttcaaatcc tccacagcta
    16981 catcgccaat ctttttctct aagagtctgc gataaacagg atgctccaag aagtcttgac
    17041 tagatagagg agcatggagg actagctgat aaacatcccc cttttgatag agggtcaaga
    17101 gattaaaagc agataagatt ttcaatgatt ttatcagtct atccatccca aagttaagat
    17161 ggttgagaat gcttgaaaaa agatattcct ttctaccatt atcccaaaaa ctgattgtat
    17221 aaagataaag gctcagtgcc tcctgaccga taatcgggag gtagcactgt accagagatg
    17281 aggtatcttg cgacacccga ttattcttta gataagaaaa acggtcaatt ggcttcattt
    17341 atctttcctt tttcttttta gaggactggg tgatttgttg gagcaagctc tctaactcac
    17401 tgacatcctt aaaactacga tagacactag caaaacgtac ataggtaatc tcgtccaatt
    17461 cagccaactc ctccatgacg agtgaaccaa tgtcctcact ttgaatttca ttttcatttc
    17521 gaccacggag tttctgttcg atacgattga ctaccatgtt gatttcatca cttgacacag
    17581 gacgtttctg ggctgagcgg ataatcccat taaagatttt atctctggag aattgttccc
    17641 gtgtgccatc ttttttaaca accactaagg ttctttcttc tactcgttcg taggttgtaa
    17701 aacggtgttg gcattcgtcg cactcacgtc ttctacgaat ggtgttccct tcttctgctt
    17761 ggcgactatc gataacactt gacttggtag ccccacattt tggacaacgc atcctttccc
    17821 tccttatcgt tttcttttca ttataccatt ttttaagcga ttcccaaaac aattcttctt
    17881 tttgcttgac aagttttttg ttttgttgta ttatttaatt aagacaaaag agtaaaagaa
    17941 aggagactaa gatgtcctgg acatttgaca acaaaaaacc catctattta cagattatgg
    18001 agaaaatcaa gcttcagatt gtttcccata cactggaacc caatcaacaa cttccaaccg
    18061 tgagggagct agctagcgag gctggtgtca atcccaatac catccaaaga gccttatcag
    18121 accttgaacg agaaggattt gtctacagca agcgaacaac tggacgattt gtgactaagg
    18181 ataaggagct aatcgctcag tcacgcaaac aattatcaga agaagaattg gaacacttcg
    18241 tttcctccat gacccatttt ggctatgaaa aagaagaact accaggcgta gtcagtgatt
    18301 atattaaagg agtttaagcc tatgtcatta ctagcatttg aaaatgtatc caaatcatat
    18361 ggagcaacac cagcccttga aaatgtttct cttgacattc cagctggaaa aattgtcggc
    18421 cttcttgggc caaacggctc aggaaaaaca accctgatta aactaattaa tggcctctta
    18481 caaccagatc aaggacgtgt cctcatcaac gacatggacc caagcccagc aaccaaggcc
    18541 gttgtagctt atttgcctga tacgacctat ctcaatgagc aaatgaaggt caaagaagcc
    18601 ctaacctact tcaagacctt ctataaagat ttcaatcttg aacgcgccca tcatctactt
    18661 gcagacctgg gcattgatga aaatagtcgt ctcaagaaac tatcaaaagg aaacaaagaa
    18721 aaggttcaac tgattttggt tatgagccgt gatgctcgtc tctatgtttt ggatgaaccc
    18781 attggtgggg tggatccagc agcccgtgct tatatcctca ataccattat caacaactac
    18841 tcaccaactt ctaccgtttt gatttctacc cacttgattt ctgatatcga gccaatcttg
    18901 gatgaaattg tcttcctaaa agacggaaaa gtcgtccgtc aaggaaatgt agatgatatt
    18961 cgctacgagt caggtgaatc cattgaccaa ctcttccgtc aggaatttaa ggcctaagca
    19021 aaggagatta tttatgtttt ggaatttagt tcactacgaa tttaaaaatg ttaacaagtg
    19081 gtatttagcc ctctacgcag ccgtgctagt cctttctgcc ctcatcggaa tacagacaca
    19141 aggctttaaa aatctacctt accaagaaag tcaggctact atgctacttt ttctagctac
    19201 agtctttggt ggcttgatgc ttacacttgc gatttcaacc attttcttga ttattaaacg
    19261 cttcaaaggt agtgtctacg accgacaagg ctatctgact ttgaccttgc cagtttctga
    19321 acaccatatc atcacagcca aactaatcgg tgcctttatc tggtcattga ttagcaccgc
    19381 tgtattggct ctaagtgctg ttattattct ggctttaaca gctccagaat ggattcctct
    19441 ttcttatgtg attacatttg tagaaacaca tctccctcag atctttctta caggtatatc
    19501 cttcctacta aataccattt caggaatcct ctgcatctac ctggctattt ccattggaca
    19561 gcttttcaat gaataccgta cagcactcgc tgttgcagcc tacattggta tccaaatcgt
    19621 cattggattt attgaacttt tcttcaatct tagttccaat ttctatgtca attcactggt
    19681 aggactcaat gaccatttct atatgggagc aggtatagcc attgttaaag aactcatatt
    19741 catagctatc ttttatctcg gaacctacta catcttgaga aataaggtta atttgcttta
    19801 aataattttt acctagatat gtaacatact catagaacaa aagagaccag gcaaaaagtc
    19861 tttaaaatta gaaaacgcat agtatcaagt gttaaaaatc cttgatatta tgcgtttttt
    19921 gtgagctgac ttatttcctt tcgctatatc gcaaaatgaa ataagaacgg aacgatggga
    19981 ttttggaatt caaatcaatt tataagaatg ttttagaagt aatattatcc tattccagat
    20041 tcagttcact atacaattga gttttcaagc aacctgttta cataatgtgt acataattag
    20101 gttcgtgatt ccaccctttt cacctttaaa aacctcgctt tcgcaaggct cttctattta
    20161 taagataagg cacgtttaaa ggttttccaa atccctaaat catccgtttg aagaacgaga
    20221 ctagcataca tgcgtccgat aaatcctgtt gctaccaccg caaaaatcac tgtaatagca
    20281 agtgaaatcc atgcttctgc tccccccgca tagccattaa tcgttcgaaa cggcataaag
    20341 aaggtcgaaa taaagggaat ataagaacca atcttcaaga ggagattgtc accagctgca
    20401 cctagagctg tcactccaaa aaaaccaccc ataatcaaaa tcatcaaagg cgacaaggct
    20461 ttccctgagt cctcaggacg agaaaccata gatcctagga aggctgccaa gactacgtac
    20521 atgaaaagac tgatcaaaat aaagagcaag gtattcagtg agatagcatc tcccaagtga
    20581 tccaaaatac cagactgagc caagaatggc aaatctttaa agagcaaaac ggcagccaga
    20641 ccacctacaa catagatccc aatatgcgtt aaaatcacta gaaacagagc catcatccgc
    20701 gcatagaaat agtgacttgc ccttatgcta gaaaaaacga cttccataat tttggtgcct
    20761 ttttcactgg caacttcctg agctgttaca cccgcatagg taatcagaat catataaaga
    20821 aagaatccta aggcacctgc tgcaattgtt tgaataaact ttttattttc cttggcttca
    20881 tcaatctttt ctgtgaattg aattgtctgc gctaagcgtt tttcctgctc ttgagacaag
    20941 gaagcagttg aacgattaag ctgattttgc agttcattga gtgtacctgt aacctcaaat
    21001 ttaattccat tttcaagcga tgtttcgcca tgataaactg cctttagaac actatcttct
    21061 tgatcaatgg tcaaataacc ttttaatttt tcttctttaa ttgcttcttt ggcacttgct
    21121 tcgtctttat agtcgaagtt aacaccattt acattcttca gtccttctgc tacagatggc
    21181 actgttgtca ctactgccac tttattattt ttagccatag aagaaccttg gatatgccca
    21241 attcctacag agattcctaa aaagaggaac ggcgaaatca ccataaagaa gaaactccat
    21301 gactcgacat gtcgaagata ggtttccttg attacaaccc acatatttct catacttcca
    21361 ctcctgattc tagtttaaag atttcatcga tagttggcgc ttgttggtca aatgttgcga
    21421 tatattgacc ttgagtcaag attgggaaga gttcccttcc agcgctctca tcctccaaaa
    21481 tcaatttcca actgccttgt ttggtcaagc tcacctgttt gacatgagga agattttcca
    21541 attcttcctt gcttcgttca cttgaaacaa agagacgcgt tttcccgtat tgattgcgga
    21601 catcctgaac tggtccgtgc aagaccacac ggccatctcg gatcatcaga atatcgtcac
    21661 aaagttcctc aacattggtc atgacatggt cagaaaagat aatggttgct ccgcgctctt
    21721 tttcctgaaa aatgacttgt ttgagcaatt ctgtattaac tgggtccaat ccactaaaag
    21781 gctcatccaa gataatcagg tctggttcat gaatcagagt aataatgagc tgaatcttct
    21841 gctgatttcc ttttgacaga ctcttgattt tatctgtcag ctttcctttc acttccaacc
    21901 tcttcatcca ttgagggagt ttttctttga cttctttggc atccatgcct tttagagtcg
    21961 ccaagtagcg aacttgttca agaactgtca atttaggcat gagactgcgt tcttcaggca
    22021 gataaccaat ccgagcatag gtctcctgac gaatatcctg accatccaga ccgatttctc
    22081 cctgatattc taggaatttc aaaatactat ggaaaatcgt tgtttttcca gcaccatttt
    22141 ttccgactag tcccaaaata cgacctggtc gcgcttgaaa gtcaatacca aacaaaactt
    22201 gcttggagcc aaaacttttc tctagacttc ttacttctag catctttcac ctccgaaatt
    22261 tcttgcactc attatactcc tttttgatag cctttacaat gtttttgtcc atttttagaa
    22321 gactattgct gtgtaaaata tggcctggag cacttttata ctcaatgaaa agcaaagagc
    22381 gaactaggaa gctagccgta ggctgctcaa agtacagctt tgaggttgca gataaaactg
    22441 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaact
    22501 atatctacgg caaggcgaag ctaacgtggt ttgaagagat tttcgaagag tattagtgat
    22561 aaatccatta tacagtagca aactcaattt ataccttccg ctcctcaact gtctattttt
    22621 aatcctgaat tgttatttga gtaactcctt tttcctcata aagttttctt cctctaaaac
    22681 ttctggaaaa aagcgaatag tttcagacaa catttttata agaaacaagt tcatctgtca
    22741 tttcaagaag gagtaatcct ttatctacta atggacggaa cggaattcaa ccgcttgtcc
    22801 gatatatttt ctaaggatta tatagtaaaa tgaaataaaa acaggacaaa tagatcggga
    22861 cagtcaaatc gatttctaac aatgttttag aagtagatgt atactattct agtttcaatc
    22921 tgctatatct attatgcaca ccactatagg atctaataaa aatcacaaca agttcattca
    22981 tagatggtta cctcagggaa ctaagaaaac gactacaaag gaagtcgcat tcatcgaaaa
    23041 gtggattaac aactatccta aaaaatgctt gaactacaag tcccccagag aagacttctg
    23101 gatgactaac ttgaacttga aatttagcaa taattaattc accatctaac tatatttagt
    23161 aattatttca gaactgatta atattaaaat taactaacaa ttcaaaggat tcatactagc
    23221 cataaattac gtccatcaga gagagactct tactactttt agattttagt ctttctagct
    23281 tcagaataca tctaaacttt agggaaaatg actattcgaa agcgcgaatg cctcaaaatt
    23341 atctcagata agctattcga aacttagaat gcttttaaat ttatggaatt gcgattattc
    23401 gaaacctaga atgcatataa cctttagttg acagacctat tctaagtctc gaagggctat
    23461 ttactttcta ttccttatca aaaaagactc attccccctt tctcctccaa aatatggtat
    23521 agtagaaata tactatctat gaggagttta catgtcacag gataaacaaa tgaaagctgt
    23581 ttctcccctt ctgcagcgag ttatcaatat ctcatcgatt gtcggtgggg ttgggagttt
    23641 gattttctgt atttgggctt atcaggctgg gattttacaa tccaaggaaa ccctctctgc
    23701 ctttatccag caggcaggca tctggggtcc acctctcttt atctttttac agattttaca
    23761 gactgtcgtc cctatcattc caggggcctt gacctcggtg gctggggtct ttatctacgg
    23821 gcacatcatc gggactatct acaactatat cggcatcgtg attggctgtg ccattatctt
    23881 ttatctagtg cgcctatacg gagctgcctt tgtccagtct gtcgtcagca agcgcaccta
    23941 cgacaagtac atcggctggc tagataaggg caatcgtttt gaccgcttct ttatttttat
    24001 gatgatttgg cccattagcc cagctgactt tctctgtatg ctggctgccc tgaccaagat
    24061 gagtttcaag cgctacatga ccatcatcat tctgaccaaa ccctttaccc tcgtggttta
    24121 tacctacggt ttgacctata ttattgactt tttctggcaa atgctttgac acgtaaaaaa
    24181 tccgtttggt ttcccaagtg gatttttaaa gcgtagatta actatagctt gatactaaat
    24241 atactttggt atggaaatta tgcatatttt tcgatagtga ggcgaggact tacctagcct
    24301 ttccgccgtg atagaaacac ctgaaatcta atggtttcag gtattcggaa actttgagac
    24361 actaggctca aagtttaggt atggaatttc gaagaaagtc gctaccgtcc gtaatcactt
    24421 aaggaaaggc tcaaaaatat tgttttcaac cacaaaatcc gtttggtttc ccaagcggat
    24481 tttgtgcttt attttgaaac ttcttttgca agaacaaagt tcccaagtgt ggcagaacca
    24541 tttcctgcga ctgctggcgt cacgatatag tcacgcacat ctggtactgg taggtaacca
    24601 ttaagaagag atgtaaattt ctcacggaca cggtccagca tatgttgttg agccatgacc
    24661 cctccaccaa agacaatcac gtctgggcgg aaagtcactg tcgcattaac cgcagcttga
    24721 gcgatatagt aggcttgaac atcccaaaca gggttgttga gttcaatatt ttccccacgt
    24781 acacctgtac gagcttccaa acttggacca gctgcataac cttctagaca tcccttatgg
    24841 aaaggacaaa cacccttaaa ctctttttca atatccattg ggtgtctagc aacataataa
    24901 tgacccattt cagggtgacc cacaccaccg ataaactcac cacgttggat gacgcctgca
    24961 ccgatacctg taccgattgt gtagtaaacc aagttttcga tacgaccacc agcattgtta
    25021 cgggcaacca tttcaccgta agcagagctg tttacgtctg ttgtgaagta cattggcacg
    25081 tttagggcgc gacgaagggc accaagcaag tctacatttg cccagtttgg ttttggagtc
    25141 gtcgtgataa agccataagt ttttgagttt ttgtcaatat caatcggccc aaatgaacca
    25201 actgcaagac cagcaaggtt atcgaatttt gagaagaact caatggtttt atcgattgtt
    25261 tcgattggag ttgttgttgg aaattgtgtt ttttctacaa cgttaaagtt ttcatcaccg
    25321 acagcacaga caaactttgt accgcccgct tccaagcttc catataattt tgtcatgata
    25381 aacctcttgt ttttattttc tttattatag catacttcga aagtctaaat gtctctattt
    25441 tttagatttt cctctgtaaa tcttactatc taataaaaac gaacaaacat gtcatttgtt
    25501 cgttttcaca ttagagagga ttgattagat tttcacttcg atcacagcat cccccttcga
    25561 aactgaacct gttgcgactg gagctactga agcgtagtca gctgtatttg taacgataac
    25621 cattgttgta tcatcaagtc cagctgcagc gattttgttt gagtcaaatg ttccaagaac
    25681 atcgccagct ttcaccttat taccttgagc aacttttgct tcaaaaccgt caccgttcat
    25741 agatacagtg tcaataccaa cgtgaatcaa aacttcagca ccatttcttg ttttcaaacc
    25801 aaaagcgtgc cctgttggaa aggcaattga aacttcagca tcagctagtg catagaccac
    25861 gccttgactt ggtttcacag cgataccttg tcccatagct ccacttgaga agactgggtc
    25921 attgacatca gcaagagcga caacatcacc gacgatagga gttacaagtg tttcattttg
    25981 aagagctgct ggcgcaactt cttctttttc ttcagccact tcagcttgtt ttgcagctgc
    26041 agttgcgtct acttcatctt cgtaaccaaa catgtaagta agagcaaaac caagggcaaa
    26101 tgatacagct accataagaa ggtattgtgg aagttgtccg ttaccaacat aaagcattgt
    26161 accagggatg atggtgatac cattaccagt accagcaagt ccaaggatag aagccaatcc
    26221 accaccgatt gcaccagcaa tcaatgaaag gaagaatggt ttacggaagc gcaagttcac
    26281 cccgaagata gcaggctctg taatacctag gaaggcagaa agagcagccg ggaaagcaag
    26341 tgttttcagt tttggatttt ttgttttaac accaaccgca acagtagcag caccttgagc
    26401 tgtcatagca gctgtgatga tagcgttgaa tgggttagca tggtcagcag caagtaattg
    26461 cacttcaagc aagttgaaga tgtggtgcac acctgacacg acgatcaatt ggtgaacccc
    26521 accaatcaag aaaccaccaa gaccaaatgg catgctaaga atcgcttttg tagcaataag
    26581 gatgtagttt tcaacaacgt ggaaaactgg tccaatgaca aagagtccaa ggatagacat
    26641 gaccaaaagt gtcacgaatg gtgttaccaa gaggtcaatg acatctggaa caaccttgcg
    26701 gacagctttt tcaaatttag ctccgacaac cccgatgatg aaggctggaa gaacggaacc
    26761 ttgcaaacca acaacaggga tgaaaccaaa gaagttcatc gctgttactt caccaccttg
    26821 agcaactgcc caagcgtttg gaagtgagcc agagacaagc atcataccaa gaacgatacc
    26881 aacggcagga tttccaccaa atacacggaa ggttgaccac acaaccaaac ctggcaagat
    26941 gatgaaggct gtatctgtca agatttgtgt gtaagttgca aagtcacctg gaagtggcat
    27001 ttcaagagcg ttgaaaagac cacgcacacc catgaagaga cctgtcgcta cgataactgg
    27061 gatgattgga acgaaaacat caccgaaagt acggatagca cgttggaacc agttcccttg
    27121 tttagcaact tctgctttca tgtcatcctt agatgatgtt ggtaagccaa gtacaacaac
    27181 ttcatcgtac attttgttaa ctgtacctgt accaaagata atttggtatt gccctgagtt
    27241 aaagaaagca ccttgaactt tttccaagtt ctcaatcact tctttattga ttttctcttc
    27301 atctttgacc atgacacgta gacgagtcgc acagtgggca acactattga cattttcacg
    27361 tccgcccaag gcatcgatga ctttttttgc aatttcctga ttgttcattt gcaaaaatct
    27421 ccttatataa cattttgttc ttgtttgaaa gcgattttat tcgcccttac gactattatt
    27481 ttatcatgtt ttaaaaatat gtcaagcgtt ttgcagaaaa aatattctat ccacttagtg
    27541 ggcaagtttt agattgattg tttttgactg tttcatcagg aattccttga aaaataagtt
    27601 tgaaaccttg gttaaaaagt cttttatttc attatctttc acattttcgt aaaaatttga
    27661 ttgatttcct gtatttattt tatgataatc gtttgacagt ttttcctctt ttttaacata
    27721 aaaggcttgc attttttatc gaaaacagtt actattaaaa gtgataagat ttttggagga
    27781 atgaatggaa tggacaactg agcgtcgtta cagactttat caagattgga cgcaagaaga
    27841 aattcaacat ataaaggaaa atatggcaca atctccatgg catactcatt accatgttga
    27901 gccaaaaaca ggacttctca acgacccaaa tggcttttct tactttgatg gcaagtggat
    27961 cctcttttac cagaattttc cttttggtgc agcccacggt ttgaaatctt gggcacagct
    28021 agaaagtgat gatttggttc actttaaaga aactggaatc aaagttttac cagatactcc
    28081 attagatagc cacggtgcct actctggttc tgccatgcaa tttggcgata acttattcct
    28141 attttataca ggaaatgttc gcgatgaaaa ctggatccgt cacccatacc agatcggtgc
    28201 tttgatggac aaggagggta agattacaaa gattgacaag atcttgattg accagccagc
    28261 agactctact gaccacttcc gcgatccaca aatttttaac tttaaaggtc aatactatgc
    28321 tgtcgtcggt ggacaggact tggagaaaaa aggcttcgtc cgtctctaca aggctgtcaa
    28381 taacgactac acaaactggc aagcagttgg cgaccttgac tttgctaacg accgtactgc
    28441 ctacatgatg gaatgtccta atctggtctt tgtagaggaa catcctgtcc ttctctactg
    28501 tccacaagga ttggataaga aagttctaga ctacgataat atctttccaa atatgtataa
    28561 gattggggct tcctttgacc ctaaaaatgc caaaatggta gatgtgtctc aacttcaaaa
    28621 catggattac ggtttcgaag cctatgcaac tcaagccttc aacgctcctg atgggcgtgc
    28681 tctagcagtt agctggcttg gtttgccaga tgtttcttac ccatctgacc gttttgacca
    28741 ccaaggaacc ttctctttgg tcaaggaact cactatcaaa gacgacaagc tctaccagta
    28801 tccagtcgct gctattaagg accttcgtgc ttctgaagaa gccttctcaa accgttccca
    28861 aaccaagaac acttacgaac ttgaactcaa cttggaagct aatagccaga gcgagattgt
    28921 cttacttgct gataaagaag gtaagggact ttcaatcaac tttgaccttg taaacggtca
    28981 agtgacagtg gatcgtagcc aggctggaga acagtatgcc caagaatttg ggacaactcg
    29041 ttcttgccct atcgagaatc aggctactac tgctacaatc ttcatcgata actctgtctt
    29101 tgaaattttc atcaataaag gagaaaaagt attttctggt cgtgtcttcc cacatgcgga
    29161 ccaaaatggt atcctgatca aatctggaaa cccaactgga acttactatg aattagatta
    29221 tggtcgcaaa actaactgat gtcgccaaac ttgcaggcgt cagtcctact accgtttctc
    29281 gggttatcaa taaaaaagga tatctatctg agaaaaccat ccaaaaagtc aatgaagcca
    29341 tgagagaatt aggctataaa cccaacaacc tggctcgtag tctgcaagga aaatcagcta
    29401 agttaatcgg cttgattttc cccaatattt ccaatgtttt ctatgcagaa ttgattgata
    29461 aattggaaca ccaactcttc aaaaatggtt acaagaccat catctgcaac agtgaacatg
    29521 attctgagaa ggaacgcgaa tacatcgaaa tgttggaagc caatcaggta gacggcatca
    29581 tttctggtag tcacaaccta ggaatcgaag actacaatcg tgtgacagcg ccgattattt
    29641 cctttgaccg aaacctatcg ccagacatcc ctgttgtctc ctctgacaac tatgctggtg
    29701 gggttcttgc tgcccaaacc ttggtcaaga caggtgccca gtctatcatc atgattacag
    29761 ggaatgacaa ttccaattcg ccaaccggac tgcgccacgc tggttttgca tccgtactcc
    29821 caaaagctcc tattatcaat gtttccagtg acttttctcc cgtcagaaaa gaaatggaaa
    29881 tcaagaatat cttgacccgg gaaaaaccag atgccatttt tgcttcggat gatttgacag
    29941 ctattctggt cattaaaatc gctcaagaat tgggcatttc tgtcccaaaa gagctcaagg
    30001 tcatcggcta tgatgggacc tactttatcg aaaattacta ccctcaattg gctactatca
    30061 agcaaccttt ggaagagatt gcttgtctca ctattgatct tctcttgcaa aagattgaag
    30121 gcaaggaagt cgccacaact ggttacttct taccagttac gctattacca ggaaaaagta
    30181 tttaaacaca agaaaactca gaccgattcg tctgagtttt tatgatctta aattttcgag
    30241 atagcgctgg gctgtctcta ggttaaaggt tttatctgag atgaggcgct ctactagggg
    30301 agcaacttca gattcactag ccccagctag gagagctagg gatttggcct gtagtttcat
    30361 gtggccttgc tggatgcccg tacttaccaa ggctttgagg gctgcaaaat tttgagcaag
    30421 accgatggac acgataatct gggctaattc tctggcagaa ggatttccta gtagatcatg
    30481 actgagagct acacgtgggt tgaggccgat agagccaccc ttagtcgcta caggcatggg
    30541 cagggtcatc tcaccgacca attcttctct ttcaaggtcc agcgtccagc agctaagacc
    30601 ttgatagcgt ccatctcgac tggcaaaggc atgggcccca gcttcgatgg cacgccagtc
    30661 attaccagtg gcaatcaaaa tcgcatcaat accattaaaa attcctttat tatgagtagc
    30721 agctcggtaa ggatcagcct gcgcaaactg actagccaac gcaattttct ccgcaatctc
    30781 tcgtccttga tccttttggc ggctcaagta gcgaaaggcg atgcgacagc ttgcagtcac
    30841 cagagaatca gtcgcgtagt tggacaggat tcccatgaga ctctgtccct gactgagttc
    30901 ttctaagact ggtttcaagg cttccagcat ggtgttgagc atattggcac ccatggcttc
    30961 ctgggtatcg acatgaatat aaacaacgag aaagtctggt tcgcctttta tctgctcgac
    31021 atgcagatca cgcgccccac ccccacgttt aacgatagaa ggataggctt gattggcaag
    31081 ctccaagagc tccgctttct tgctggcaat cttctcttgc gctagtttag gattagcaac
    31141 ttgataaagg gctacctgcc caatcatctg gcgctgatgg acttgtgcag taaaaccacc
    31201 tgcacgcttg atgattttgc tggcatagct ggccgccgca accacagagg gttcttctgt
    31261 cacataggga acggtgtatt cctgaccgtt gacaagtacc tccggaacca gtgaataagg
    31321 cagagaaaaa gttcccacta cattctcact cagctggtct gccacagtca cgctcatctg
    31381 ttcatccttc tccagactag cttgtctctc aggactaagg agcgcctgag cttttaacag
    31441 ctcgaggcgc tcttggtatg attttttaga aaatccattc caacttatct tcattatttt
    31501 tcaaccttgc tataacggcg ttggtggtcg agaatttcaa ccaaggcaaa atcttgattt
    31561 tcatagccag caaactgggc agagtttgtt tcatccaagt ttacttcctc aaaaaagacc
    31621 ttttcatagt ctgcaacgga tagggcagtt cgttggttga gcttgttcaa acggtcttta
    31681 tccaaataag cttcatatcc ttcaaccaat tcaccactga agaactcagc cacagctcca
    31741 cttccgtaac tataaagggc gattttatcc ccagctttca agctatctgt attttccaag
    31801 agagacaaaa gtccaaggaa aagtgaacct gtgtagatat tccccacctt ttgactgtag
    31861 agaatagact ggtcaaaatg cttttgtaag aggtcttttt tctcttgagg caggctctta
    31921 tccatgattt ttttcaagcc ttttagcgct aatttaggat aaggcaagtg gaaacaaaca
    31981 gccgcaaaat catccaaagt aagctggtag cgtttttgat attcaagcca agtcgttttc
    32041 aaactatcca agtattgttg ggtagaatag acaccattta cataaggagt tgtcgagtaa
    32101 tttggtcgcc agaaatccat gatgtcacgg gtctgagcta cattgtcatt attaaaggcc
    32161 atcatgcgtg gattttgtgt aatcaacata gccacacttc cagcaccttg agttggttct
    32221 cccggagttt caataccata tttggcaata tcactggcaa tgaccaagac cttggactcc
    32281 ggagaatttt ccacatgcaa tttggcataa tggagggcag ctgtcgcccc atagcaggct
    32341 tctttaatct cgaaactacg agcaaagggc tggatgccca gcaagccatg cacaaagacg
    32401 gccgcagcct tactctggtc aattcctgac tcggtagcca caatgaccat gtcaacttct
    32461 tgtctttctt gctcagttaa aatagagtca ctagcactgg ccgccaaggt cacgatgtcc
    32521 tcagttaggg gcgcaatact caattccttg agtaagagtc ctttacttaa tttttcaggg
    32581 tcaattcccc tcgcttctgc taagtcttgt aatttcaaga cacattgact ggtcgcaaaa
    32641 ccaatcttat caataccgat tgtcatattt acctctgttt tatcattcat gtaaaaaatc
    32701 gttctatact attttatcac aaatggcagt aaaagagaga aaaaagactt gattcaccaa
    32761 atcaagcctc ttattggtca tcattttaaa gaatgattag ttgctagaga gttcaccgat
    32821 ataagtagct ttataagctc cattcacagt tatcagctcc tggaggatca aatttcctga
    32881 gtaagtcctt cccatctcat ctacaaattt ttgataaaac tgactggtcg gaatttctct
    32941 gacatcctta tcaaatgtct tgtcaagtgt tttactaacc ttctcagcaa tcaattgatg
    33001 ctcttgccat ccactttgaa actctgagcc ccaactagaa accatgactg ggataaacaa
    33061 caaggtcagt agacttacag acaataagga aaatagtaga cttcctgcaa aactagaatc
    33121 ctagttcatg attgataatg ccagcaatca aattcattcg taatccgaag cgtttacgat
    33181 gatttcgata gattgttgaa aacattttaa acgtttttac tttggcaaag atgttctcaa
    33241 ccttgcttct ctccttggat agcgcatggt tacaagcttt atcttcagct gttagcggct
    33301 tgagtttgct ggatttacgt ggagtttgta cttgaggata tatcttcatg agcccttgat
    33361 aaccactgtc agacaagatt ttaccagctt gtccgatatt tctgcgactc attttgaaca
    33421 acttcatatc atgacaatag ttcacagcga tatccaaaga aacaattctc ccttgacttg
    33481 tgacaatcgc ttgagccttc atagcgtggc atttcttttt accagaatca ttcgctaatt
    33541 cttttttagg gcgattgatt tgtacttccg tcgcatcaat cattaccgtg tcctcagaac
    33601 tgagaggagt tcttgaaatc gtaaaaccac tttgaacaag agttacttca acccattggc
    33661 tccgacggat taagttgctt tcgtggatac caaaatcagc cgcaatttct tcataagtgc
    33721 ggtattctcg cacatataga aagcgttgtt aatttattta tctcattttt cagaaaattc
    33781 tttcatttgt gtaaagtcta cgatactcga tgtgttttta tataatgata cagtctgaga
    33841 atcactgttc cgctagccat tccaatagag attaccaaag ccaacatgac aaccaaggtc
    33901 gcacttgcca gtgctttatt atagtcccct gtcacaaaaa aggcagttgt tcggtaggag
    33961 agataacctg gaaccagcgg tgccaaaatg gccaagataa agaccacagc aggtgtctta
    34021 taaagaatac ttaaaatctg gctgacacaa gaaccaataa tggctgcaat gaaggtagct
    34081 acaatgacat tggtcggctc cttgagcaag agatagatta gccagacagt catgcccaaa
    34141 atccctccag gtaagagcat agaccgttgc acattgagta cgattaaaaa agtgataatg
    34201 gcaagaaaac ttgctactgc ttgtaataaa aaggttgtta gtgtcatatt agttcatcaa
    34261 taccaaggcg acagaagttc ctgcccctaa agcgagggta atgagcaggg attcaaacat
    34321 cttactcata ccagagttta tgtggttggt cataatatca cggaccgcat tggtcaaggc
    34381 aatacctggt acaaacggca tgaccgcacc agctataatc aaatctgccg ttgaaggaaa
    34441 acctgtgtag cgagcccaaa actgggcaat tatcccaaag acaaaggctc cagcaaaggc
    34501 tgtcacaaag ggaattcgga taaatttttc cacatagagg gaaaaggcaa aaccaaataa
    34561 ggtcgccact cctgccccaa gtgcgtcgta gatatttccg ctaaacataa ctgaaaagaa
    34621 aggagcgcta aaggtcgcag ccagagttac ctgcaactta gtatagggaa ggggttgagc
    34681 ttgcaaggcc gtcaattgct taaaggctgt ttctaaatca atctgccccc caaccagctg
    34741 acgagaaatc tggttcacat cgcagacttt ttcgatgtta taagaagagg aggtcacgcg
    34801 cttcatgcgc gaaatattgg tattttcaat agagaaaaag atagcggcag gcatggcaag
    34861 gacattgcaa tccacaatcc cctgcgaatg cgcgattcga atcatggtat cttctacacg
    34921 atggatttct gagccacttt taaggagaat agtccccgct agcataatca catcaatgac
    34981 ggtatttaat tcttttgatt cttccatgct ttcctccttt tatcaactcc ctctattcta
    35041 tcacaaatcc ggactcaaaa aaaatctttg ccatgaaatc atgacaaaga ttgattactc
    35101 attttgatta tccatctgct tgattatcca tctgctttta aggagtagct gaagttgttt
    35161 taggtttgta gattgaaatc ttgactctag tcttattgag gtctaccttt tcacctgctc
    35221 taggactttg ttcaacaacc atgccttctg cactacctgc aggcgctgtc gtcacttcta
    35281 caacttctat attagcttcc ttaatcccaa caatttgaat caaattgttc ttagtaaact
    35341 ccaagctgga accaatgtaa ctcggcatgg caacacttgt aactttttta gctactgtca
    35401 agacaatttg aataggttta ctcacatcat aggtcgttcc ggcacctgga ctttgtttca
    35461 taatcgttcc tggttcgctt tcgctggact cttcttcctc tatcttaatc aaattctcag
    35521 gaaccttctt ctgcttgagt tctgagatta cttctgtaga gttccgtcca atatagttcc
    35581 ctaattgaat cgtcgtagct tttttagcta ctgtcaaaac aatttgagtt gccttgctca
    35641 agtcataggt cgtaccttct ggtagacttt gcttcaggac cgttccagcc tcactctcat
    35701 tggactcttc ttcctcaatt ttaatcaaat tatctggaac ttttttctct tttaattccg
    35761 caatgacatc agaggatttc cgaccgacat aattactaat ttggaaggat tgcttgcctg
    35821 atgagacaac caaattgatt ttcgttcctt cttttcgacc agttccagcg ccaggatctg
    35881 tacggataat ccgcccttct tccacctttt cactagcctc tgtcttctcc tcaccaatct
    35941 caaaattggc ttttttgagc gttgccttgg cctctgcaac tgtctgacct gccacatctg
    36001 gaatggcaat ggttgcagga gttctggata gtatccaaat aagagaagct gccaccaata
    36061 caaggctggc caacaaaatc aggtaacgca tcttaaatct atgttttttc ggtgcttgtg
    36121 gttggtaagt ttcctctgtc acagcctggc ttggggtttt gattgatttg tgttctgtct
    36181 gcgcttgaac cttaggaata gatgtcaagg tactctgaga aaccttcggc aaggtcttgg
    36241 tatctgcctt gctcgtttca tcaaagatta acttactttc atttctacga ttgtaggaca
    36301 agctactaga caagtccaca tacatctctg aaaccgagcg gtagcgattg gtcaactttt
    36361 tagcagttgc cttgataata acattttcta aagcctgagg tacagatgga ttttctgcaa
    36421 taacggacgg caggggtttc tggaaatgct ggagggcaat ggtcaccgcg ctatccccgt
    36481 cataagggat atggcctgtc aacatctcat agaaaataat ccccatagca tagatatcac
    36541 tctgcacagt cgccttcgaa ccacgcgcct gctctgggga caagtaatga actgagccca
    36601 acatcgagtt agtctgggtc agacttgtct ctgcaaaggc tacagcaatc ccaaagtctg
    36661 tgacctttgc agtcccatct ggtgtcaaaa ggatattttg aggtttcaag tccctgtgaa
    36721 caattcctct ggtatgggcc aaacgcatgg ctaggaggat ttgtcccatg atacggactg
    36781 cttcttcatt agaaagagga taatgttcct tgatatagcg tttgaggtct agtccagcaa
    36841 catactccat tgcaagatac tgttgaccgt cttcctcacc aatatctgtt atccgaacga
    36901 tatgaggatg gtctagatct gccatagctc tcgcttcacg ctgaaaacga gctacagcta
    36961 tcgggtccgt ctggtagttg gtcctcagaa ccttcaccgc cacttcttcc ccatctaaga
    37021 ttaagtcttt ggctaggtag acatccgcca tacctcctcg accaatctgt ttgacaatcc
    37081 gatagcgtcc ggcaaaaatc ttgccgattt ggatcattct gcatcctcct cgttcataga
    37141 aacaagggca accgtaatgt tgtctaaacc tcctgcattg ttagcaaaac gaacaagtgt
    37201 ctccgtttta tctgctaaag gaatatcact ggttacaata tcacgaatct cactgcctga
    37261 aatcatgttg gtcaagccgt cactattgag caagagatag tcacctgact caaggataac
    37321 tgtcccaaaa tcaggctgaa tttcatcttt ttgcccaata gactgggtga taatattttt
    37381 ttgcggatga gcttctgcct cttctggtgt caattgacca gccttgagca attcattaac
    37441 caaggaatga tcgctcgtca actgatggta ttcttctcca cgaatcaagc cgatacgcga
    37501 atcaccaata tgagcataga tagcctgatt atcaataata gcaaggactt ccaaagtagt
    37561 tcccatgcct ctgtaagctt catcctgacc aagctggtga atcttttgat tttcaatttc
    37621 taggtaatgg gcgaaccatt cacgcacttc attgactgta tcgatctggg tatcaaccca
    37681 agctacaccc aggtctgtga ccgccatttc actagcgata ttccctgcac gatgacctcc
    37741 catcccatca gctaaaataa tcatggtacg tccagctcta ttgacatagt ggttgacata
    37801 gtcttggtta tttgttcgtt tctgaccaac atctgttaat aatgaaattt ccatgtgtca
    37861 gttccttcct aatccgatat cttgcgaaat tgactgatga agaatccatc acttccatac
    37921 aattcaggtg taatgaggat acagccgtct ttcatgatat ccttacattc atgttctagt
    37981 tttacctgct cgaactcggg atgactctct aaaaaggcct taacgacttg aaaattctcc
    38041 tctgagacga tagtgcaggt gctataagtt attataccac ctttgcctag tatttgacaa
    38101 acactaccta atatttctaa ctgaatttcc tgcaaggacg cgaaatctgc cgtttcttta
    38161 ttgtatttga tatctggttt tcggcgcaaa agaccgattc ctgaacaagg agcatccacc
    38221 aaaatcttat caaaggaatc ctggtcaaaa aactcatgca cctttctggc atccaatttt
    38281 tgagtttgaa cccgatcttc aactcccaga cgttgggcat tttcttgaat taaatccaac
    38341 ttgtggtcgt acaagtccag agcagtaacc tgacctgtcg taagataaga ggctatatgg
    38401 gctgttttcc cacctggagc cgcacaggca tcaagcactc gctcatcacc ttgtaaatca
    38461 agcgtcggag caaccagctg actggactcg tcttggatgg taatggctcc atccgcaaac
    38521 aaattatgcc ctgcaaaatg cccctgctcc ttaaccagac cagtggttgc taaaagggaa
    38581 tcattcgcct ccaacaaggc ttggatttcc tcttttcgac ttaggtctgt tacacgaata
    38641 ctggctttgt ttcgcactaa caggctttca aagatggctt ttgctctctc ctctccgtat
    38701 tcttccttga gtttggcaac tagccaaact gggagagaat aggcaatgga gtcacgcttg
    38761 ttttttcgct tgatgctagc aatatctggc cagccttcac gcaagatacg gcgaaggaca
    38821 gcgttgacca atttttcact gcctttttta cggagtttgg ctaattccac tgcttcattg
    38881 accacagcat gatctggaat tttgtccaaa tagcggagtt ggtaggcact catgagaaga
    38941 aggacataga gccagctgtc taactggtct ctgtcttcga taaagtggga taggtaccat
    39001 tccagagtca gtttacgggc taccgttcca tagactagct cggtcactaa gcccttgtct
    39061 gctgcagaga gctgactccc cttgaggtgt ttatttaagg caatatttga atatgcttga
    39121 ttcacaaaaa catcctctag cactgctaga gctaaacttc tagccgtttc tactttagtc
    39181 accaaatcgt tctcctacag tcaatgtacg tccaactcca ttgaggaagg aagcaatgtc
    39241 catcttaggc ttaccagctg gctgcacttg tttgagggat agagcccctt cagccgttgc
    39301 gacaatcaat tctttcttgc cgatagagag aatctcacct ggatttccct gaccttctac
    39361 tggtagggct tcataaatct taaagcggtc gcccttaagg aaagtatggg caacaggcca
    39421 ggggttcatt ccacgaattt ggttaaagag ttgacgattg gttttgttcc agtccagttt
    39481 ttcttccttt ggctttatat ttggagagaa ggtaacctga ctcgtatcct gcggttcagg
    39541 tttgatatca ccagcaatat aggcaggcag agtgtccaaa agcaaatcac aaccaactag
    39601 cgccaatttt tcaaacaagg tgccaacatt gtcctcatct gtgatcggaa tgctgcgacg
    39661 agaaatcata tctcctgcat ccatttcctt aaccatttcc atgatggtca caccagcttc
    39721 ctcatcccct tgaatcaagg cataatggat aggcgcacca ccacggtgtc taggaaggag
    39781 ggaggcatga acgttgacag caaagtccat gctatcaagg agtttgcttg ggagaaactg
    39841 cccaaaagca gcagtcacaa ttccatctgc tcctagcttc ataagatctt ccatctctgg
    39901 acttccagat aatttttcag gttggtagat agatagtcct gcttccttgg cagcctgctt
    39961 gactggggtt tcttggataa cttttttacg accaacagca cggtctggct gggtcacaac
    40021 ggctagaatt tcgtaacggt catctgtcaa aagtcctttt aagactgttg ctgaaaagtc
    40081 gggggtcccc ataaagatta gttttgtcat atcttctcct tcttataaaa attgctgcgg
    40141 ctcatggtca atgctgagac ggagctcact attttcccgt tcttgagtca aggccaagac
    40201 ctggttgagg gtcggcccca gctcatcttc taaacggtat ttaattaaaa tctggtaatg
    40261 atagaggttg tgggtacggg caatcggttt tggcgttggc cccagaatgg gactggtctc
    40321 tgacaagcct gaccgcaaaa tgttcatgac ttcataggca cgtttgaaaa cctcttcttc
    40381 tttcttgtga gaaagggtaa taccaatcgt gaaatagtaa ggtggatagc cgagttgtcg
    40441 tctgattccc atttcatagg cataaaagcc ttcgtaatct tgatccttgg caaatcgaat
    40501 agcatagtgc tgcgaattgt aggactgtat caagacttga cctgcttttt cagcccgacc
    40561 tgctcgacct gccacctgag tcaagagctg gaaggttctc tcagaagaac ggaaatcagg
    40621 cagattcaag gccgtatccg catttagaac tccgactagg gtaacattgg gaaaatccaa
    40681 accctttgca atcatctgag taccaagtaa aatatccgct tcccctcgcc caaactggtc
    40741 aagcaaggct tggtgactgc ctttctttcg agtcgtatcc acatccatcc tcaaaatgcg
    40801 agcttgggga aagagttctg ctagctcatc ataagccttc tgagttcccg tcccatagta
    40861 acgaatactg cggctcttac agttaggaca gacctgagga atatccttcg agaaaccaca
    40921 ataatggcag ttcatagtct tggtatccat atgcaaggtc agagaaatat cgcagttggg
    40981 acaagtatcc accgtcccac actcccgaca catgacaaag ctagaataac cacggcgatt
    41041 gagcatgaga accacctgct cttttttaac cagacggtct tggatagcct ctagcaaagg
    41101 aggcgtaaag tttgacgtct cattttgtcc gatatagtct cgaaagtcaa tcacttgaac
    41161 ctcagggatt gtagccaaag gattggcacg ttgggttaga cgtaagtgtc gatagacgcc
    41221 tttgccagca cgtgcccggc tctctaagct cggcgttgca gatccaagta ccagagttgc
    41281 ttgattatac tgagcccgta aaatagctac ctctctggca tggtaacggg gattgctgtc
    41341 ctgcttataa gccgcttcat gctcttcatc aataatcatg acacccagat ttttcagagg
    41401 agcaaagata gcagatctgg caccaacaac aacttgggca tcgccacgct ccaccttgcg
    41461 ccattcatca tacttttcgc cattggataa tcctgagtga agaatggcta ccttgtcccc
    41521 aaaacgtgct ataaaacgct cggtcatctg aggagtcaag gaaatctcag gtaccagcaa
    41581 aatagctgtc ttacccttat ccagggcacc ttggataatc tgcaagtaaa cctcggtctt
    41641 cccacttcct gtaatccctt gaagtagaaa gggaggttga gaactgccaa tagaactcac
    41701 aaccgcatca cgcgcctgtc tttgttctgg atttaactcc aaaggtctac ttgcttcaat
    41761 tccttcaaaa taagcagccg agcgttgaac ttccttttgg actatggtaa cagcaccttg
    41821 atccacaaag aagttgactt gctctcgcga gtaggactct aacaagctag ccaaggaagc
    41881 gctctctgga tgagacagca gataatctct cagttccaac tttttcttgg cacgtgtaga
    41941 aatctcaaca ccttctaatt gggcatggtc aacctcatac caagactggg tcttgacctt
    42001 cttttgatcg actgcctgat attccagacc aagcaggcct tttctagtca aacgcatcat
    42061 ttcagcttgc ttggcaaggt ctagtgaaga aaaggctagc gaatcttctg aaccaaacag
    42121 gcgtactcgt tcttcctgac tcaagccttc cagaggatag agaatcttgt catagctaga
    42181 attcagaaac cctggaagca tggccttgag gatagagatt ttgtaggaga agacagattt
    42241 gcgtaactcc tcagccagcc agagttgttc tggcgtgaga acaggagaaa aatccagcac
    42301 ctctgcaata tcttttaaat cttgctccat ctcttctcca tctgattggg acttcaaacc
    42361 aagaacaatc ccttgaatca ggcgattccc cttaccaaaa ggcacatgaa cccgcatccc
    42421 aacttccagc attccctcaa attcctccgg aatcctgtaa ctatagggct ggtccgtctg
    42481 catcaagggc acatctacga taatcttagc tagggccatc ttctcacctc ctccttgtca
    42541 gtacattctt gcaatagaaa aaataagatt gagtcccccc aaccttaaat tttttcacca
    42601 tcttcttttt ctttagcaat ttgctctttg attttctttt cttcttcttc tttgcggcgt
    42661 ttttcttctt cgatacggcg acgcactgct tcacgttttc cttctggatc tgggtgaatt
    42721 gtaacgtttc ctgattcgat ttcttctaaa gcgcgaagag ttgatttttc agacttgaaa
    42781 ccttgagttg ctggggcacc tgcttccaat tcgtgggcac gttttgcttc caagattacg
    42841 agtgaatatt ttgaaggaac cttgtcgagc aaggtatcaa tagagggttt taacatcatt
    42901 tgcttgtacc tattttctaa attttatcgg gtagttggag attttggtaa catctcctga
    42961 tagtgaccaa tgacacgatc cacacagaag tgttctgctt caatcacaca tttgacacgt
    43021 tcagcagcta ggggcacctg atcgttgaca atcgcataat catactcacg catgagggca
    43081 atttcttcct tggccttttc gattcgttgg gcaatcactt ctgcactatc tgttccacga
    43141 cctaccaagc gatcttgcaa ttcatccaaa tctggtggtg tcaggaagat aaagacagca
    43201 tctggaacct ttttcttgac ctgaagagca ccctgaactt caatttcaag gaaaacatcg
    43261 attcccttgt ccaaggtttc attgacatag gtcagaggag ttccatagta gttgccgaca
    43321 tattctgcgt attccaacat ctgtccttga cgaatcagct cttcaaattc ttcacgagta
    43381 cggaagaaat agtcaacacc gtccacttct ccaggacgtt gtgcgcgtgt cgtcatcgat
    43441 acagaatatt gaaattggtt ttcagaactc tcaaaaatct ctcttctaac cgttcctttt
    43501 ccaacccctg aaggaccaga aaaaacgatt agtaagcctc ggtctgccat tgtgtctcct
    43561 tttagtcaat ctgtgaaata acatttctct agaataatgg caaaaagcca gattatcctt
    43621 tacagtcttt ctatctagtg taacaaaaaa gcagtaattt ttcaactgct ctttcttatt
    43681 ta
//
LOCUS       DAVIME010000013        43412 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVIME010000013 DAVIME010000000
VERSION     DAVIME010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.013"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..303)
                     /locus_tag="VV588_000747"
     CDS             complement(<1..303)
                     /locus_tag="VV588_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083120.1"
                     /translation="MKLNDFLKPELLGNKFIAVKGYTEVLDRETNKPVALRLNVSIQD
                     EDSDFFMEMIQVKVNTLSPTASVQEMANNKTCPVTLKDLNVGQYNGNLWFSCSNVIL"
     gene            complement(393..1715)
                     /locus_tag="VV588_000748"
     CDS             complement(393..1715)
                     /locus_tag="VV588_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HEU7083121.1"
                     /translation="MFKLRQSADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIR
                     APTFVQILFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTSKDGS
                     GYEKIVRSAVLEYEIDRQKGHVLIKALITGDEFSKKVQSLDDVLSDVLELELEEKIIR
                     PSFIEYHFYYIKPKRLVLQSHSQRQEIDSLDIDLGYGVNYNPVKCSHILVSGGTGSGK
                     SVLISVLILEFLKRQSTVYIADPKNSDLGSLSHYFGNKYVATTPNNIARIVRVVVEEM
                     QERYQVMRDNFQYGSNFTNHGFKPVWLIFDEMGAFQATGSDKKSREIITEVMDGIKQI
                     ILLGRQSGIFILVSTQQVNASTTLSTELRDNLGLRIALGANSSEGYHMVFGSATPDKL
                     KPIEEKGSGYLYIQGSGKESAQYWESPYLDTTQFDFIKELQLYVTKSK"
     gene            complement(1721..1939)
                     /locus_tag="VV588_000749"
     CDS             complement(1721..1939)
                     /locus_tag="VV588_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083122.1"
                     /translation="MSDNLKAYLFLLGFVILAGIAIFIFPQGHFFSNSILILGCIPLL
                     ISTYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(1979..2734)
                     /locus_tag="VV588_000750"
     CDS             complement(1979..2734)
                     /locus_tag="VV588_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU7083123.1"
                     /translation="MIQLTASTWNINLRSRKGKQIPEMIAQELAQQNSDIICLTEYVK
                     TDNHSQFCSSLQTNGYTIFEDVRTIDFGNEILIAIKSDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKIGGENVFEDFKHRKTQLDKLIFNLPIHENTIILGDFNNG
                     FFKQNDDTHSYQGKPREFYSYPLLKSEMNKAGLTVHTPSEENSWKYCKLDHIIGNIPI
                     SNVCYSWRFLENPDYQNKVGFPDHAILSATISL"
     gene            complement(3163..3666)
                     /locus_tag="VV588_000751"
     CDS             complement(3163..3666)
                     /locus_tag="VV588_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083124.1"
                     /translation="MTQFQVRISGEAAYYLRMLKEKYETSEGINITKATILTRAFQNS
                     KTVTNWTKVVQDNSISLKNIYPVEEKELKLNVALSDEVAEGIKKYKEILPSATNTQSV
                     TLGVCVKFLLKAELMTQLNHDISEPEKDFDKKFSILEKQLLEIVAPVNHKLLSDTIWN
                     FKNNFIK"
     gene            4095..5372
                     /locus_tag="VV588_000752"
     CDS             4095..5372
                     /locus_tag="VV588_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU7083125.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKIDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFSLNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            5448..6932
                     /locus_tag="VV588_000753"
     CDS             5448..6932
                     /locus_tag="VV588_000753"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU7083126.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGETVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            6993..8273
                     /locus_tag="VV588_000754"
     CDS             6993..8273
                     /locus_tag="VV588_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU7083127.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            8277..8897
                     /locus_tag="VV588_000755"
     CDS             8277..8897
                     /locus_tag="VV588_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU7083128.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADISRIFETK"
     gene            9063..10241
                     /locus_tag="VV588_000756"
     CDS             9063..10241
                     /locus_tag="VV588_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU7083129.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVAPSTGTSVPEEQTAETTRPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATETTATSSEAKEVASSNGATAAVSTYQPEETKTISTTYEAPAAPDYAGLAVAK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            10754..11092
                     /locus_tag="VV588_000757"
     CDS             10754..11092
                     /locus_tag="VV588_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU7083130.1"
                     /translation="MTRYQILLFLLEHSLCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            11103..11471
                     /locus_tag="VV588_000758"
     CDS             11103..11471
                     /locus_tag="VV588_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU7083131.1"
                     /translation="MSIITIILTTIVAWEHFYIFYLESIATQSDATSRVFNMEREELA
                     HPSVSLLFKNQGIYKALLGVCLLYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            11600..12196
                     /locus_tag="VV588_000759"
     CDS             11600..12196
                     /locus_tag="VV588_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU7083132.1"
                     /translation="MSPFEAIKGLPAEIHGAEVRWLEVPTVFHKSAQVLEEEMNRYQP
                     DFVLCIGQAGGRTSLTPERVAINQDDARTSDNEDNQPIDRPIRPDGASAYFSSLPIKA
                     MVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVKAGFMHIPYMMEQVVNR
                     PTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12224..13081)
                     /locus_tag="VV588_000760"
     CDS             complement(12224..13081)
                     /locus_tag="VV588_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU7083133.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            13211..14353
                     /gene="tgt"
                     /locus_tag="VV588_000761"
     CDS             13211..14353
                     /gene="tgt"
                     /locus_tag="VV588_000761"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU7083134.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            14454..16271
                     /locus_tag="VV588_000762"
     CDS             14454..16271
                     /locus_tag="VV588_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU7083135.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            16424..17575
                     /gene="nagA"
                     /locus_tag="VV588_000763"
     CDS             16424..17575
                     /gene="nagA"
                     /locus_tag="VV588_000763"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU7083136.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            17738..18796
                     /locus_tag="VV588_000764"
     CDS             17738..18796
                     /locus_tag="VV588_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU7083137.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            18947..19312
                     /locus_tag="VV588_000765"
     CDS             18947..19312
                     /locus_tag="VV588_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU7083138.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            19388..20329
                     /locus_tag="VV588_000766"
     CDS             19388..20329
                     /locus_tag="VV588_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU7083139.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            20277..21293
                     /locus_tag="VV588_000767"
     CDS             20277..21293
                     /locus_tag="VV588_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU7083140.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            21295..21621
                     /gene="comGC"
                     /locus_tag="VV588_000768"
     CDS             21295..21621
                     /gene="comGC"
                     /locus_tag="VV588_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU7083141.1"
                     /translation="MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            21614..22018
                     /locus_tag="VV588_000769"
     CDS             21614..22018
                     /locus_tag="VV588_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU7083142.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            22023..22283
                     /locus_tag="VV588_000770"
     CDS             22023..22283
                     /locus_tag="VV588_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083143.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVNINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            22246..22707
                     /locus_tag="VV588_000771"
     CDS             22246..22707
                     /locus_tag="VV588_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU7083144.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            22685..23131
                     /locus_tag="VV588_000772"
     CDS             22685..23131
                     /locus_tag="VV588_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU7083145.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            23234..23828
                     /locus_tag="VV588_000773"
                     /pseudo
     CDS             23234..23828
                     /locus_tag="VV588_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            23889..24842
                     /locus_tag="VV588_000774"
     CDS             23889..24842
                     /locus_tag="VV588_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU7083146.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            24893..26083
                     /locus_tag="VV588_000775"
     CDS             24893..26083
                     /locus_tag="VV588_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU7083147.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADVIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            26232..26603
                     /gene="rnpA"
                     /locus_tag="VV588_000776"
     CDS             26232..26603
                     /gene="rnpA"
                     /locus_tag="VV588_000776"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU7083148.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            26578..27402
                     /locus_tag="VV588_000777"
     CDS             26578..27402
                     /locus_tag="VV588_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU7083149.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            27421..28407
                     /locus_tag="VV588_000778"
     CDS             27421..28407
                     /locus_tag="VV588_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU7083150.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            28458..29081
                     /locus_tag="VV588_000779"
     CDS             28458..29081
                     /locus_tag="VV588_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU7083151.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            29212..30669
                     /locus_tag="VV588_000780"
     CDS             29212..30669
                     /locus_tag="VV588_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU7083152.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            30692..30973
                     /locus_tag="VV588_000781"
     CDS             30692..30973
                     /locus_tag="VV588_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7083153.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            31050..31535
                     /locus_tag="VV588_000782"
     CDS             31050..31535
                     /locus_tag="VV588_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7083154.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            31552..32217
                     /locus_tag="VV588_000783"
     CDS             31552..32217
                     /locus_tag="VV588_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU7083155.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDIFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            32221..33084
                     /locus_tag="VV588_000784"
     CDS             32221..33084
                     /locus_tag="VV588_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU7083156.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            33086..33790
                     /locus_tag="VV588_000785"
     CDS             33086..33790
                     /locus_tag="VV588_000785"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU7083157.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            33969..35642
                     /locus_tag="VV588_000786"
     CDS             33969..35642
                     /locus_tag="VV588_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU7083158.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            35754..36845
                     /gene="ulaG"
                     /locus_tag="VV588_000787"
     CDS             35754..36845
                     /gene="ulaG"
                     /locus_tag="VV588_000787"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU7083159.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            36959..38935
                     /gene="tkt"
                     /locus_tag="VV588_000788"
     CDS             36959..38935
                     /gene="tkt"
                     /locus_tag="VV588_000788"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU7083160.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGINTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            39052..39351
                     /gene="yajC"
                     /locus_tag="VV588_000789"
     CDS             39052..39351
                     /gene="yajC"
                     /locus_tag="VV588_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU7083161.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            39398..39826
                     /locus_tag="VV588_000790"
     CDS             39398..39826
                     /locus_tag="VV588_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU7083162.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            39828..40238
                     /locus_tag="VV588_000791"
     CDS             39828..40238
                     /locus_tag="VV588_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083163.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            40538..43189
                     /gene="adhE"
                     /locus_tag="VV588_000792"
                     /gene_synonym="adhC"
     CDS             40538..43189
                     /gene="adhE"
                     /locus_tag="VV588_000792"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU7083164.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSVHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFRPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        13349 a         7666 c         9449 g        12948 t
ORIGIN      
        1 tagaattaca ttagaacaag aaaaccataa atttccattg tattgaccta cgtttaaatc
       61 ttttagagta acaggacagg ttttattatt tgccatttct tgaacagaag cagtagggga
      121 taatgtattt actttgactt gtatcatctc cataaagaaa tcagaatcct catcttgaat
      181 tgacacgtta agtcgtaaag ctacgggctt attagtctct ctgtctaata cttctgtata
      241 gccttttact gctataaatt tgttgccaag cagttctggc tttaaaaaat catttagctt
      301 catgtgtacc tcttttctat catcgcagag cgatgaggaa cagatatttt tgctgaaaat
      361 ctattaaatt taagcaaaaa tatctgttga aattattttg actttgttac gtataattgt
      421 agttctttta taaaatcgaa ttgagttgta tcaagataag ggctttccca gtattgggca
      481 gattctttac cagagccttg tatataaaga tagcctgaac ctttttcttc aataggtttt
      541 aacttatcag gagtagccga accaaagacc atgtgatagc cttcactaga attagcacca
      601 agagcaattc tcaatcctaa attatctctg agttcagtac ttaaagtagt actagcattt
      661 acttgttggg tagacactag gataaaaatg cctgactgtc ttccaagtag aatgatttgt
      721 ttaatcccat ccataacttc agtgataatc tctcttgatt ttttatctga acctgtagct
      781 tgaaatgctc ccatttcatc aaatataagc catactggct taaatccatg gttagtaaaa
      841 tttgaaccat actgaaagtt atcacgcatg acttgatatc gttcctgcat ttcctcaact
      901 acgactctca caatgcgagc tatattattt ggggtggttg ctacgtattt atttccaaag
      961 taatgagaca agctacctag gtcagagttc ttagggtcag ctatataaac tgttgattga
     1021 cgttttagaa attctaaaat caaaacagat ataagcacgg atttcccact tccagttcca
     1081 cccgatacta aaatatgtga gcatttgaca ggattataat ttacaccata tcctaaatct
     1141 atatcaaggc tatctatctc ttgtctttgg ctgtgagatt gtagaactaa cctttttggt
     1201 tttatgtaat agaaatgata ttctataaaa ctaggtcgaa taatcttttc ctcaagctct
     1261 agttcaagca cgtcagaaag tacatcatca agagattgaa cttttttact aaattcatcg
     1321 cccgttataa gagctttgat aagaacatga cctttttgtc tatctatctc gtattctaat
     1381 actgcacttc taacgatttt ttcatagcct gaaccatctt tagatgtggt ataaagtctg
     1441 tttgtgtgga gtacataaag taagctctca cgtataataa ggtaatgctc taagtcatat
     1501 cgaaaaattt ttattttcag atgaatttta tagataataa atccacctaa aaatatgaag
     1561 agaatttgaa caaaagttgg agccctaata ttaacaatag tggaaaatag aatgcaggca
     1621 gagatactta gtatcagcca gtgcattatt tttaacttat aacaggaaat tatattgttt
     1681 cttgttaaat cagcactttg tcttaattta aacatattag ttagatacct tttattttat
     1741 ctaaaagctc ttttaaaagt tcgtaaaacc ctaagagctt gatttttgcg aaataatatg
     1801 ttgagataag tagtggaata cacccaagga taaggataga attcgaaaag aaatgtcctt
     1861 gagggaatat aaaaattgct atgccagcta atatcacaaa tcctaaaaga aatagatatg
     1921 cttttaaatt atcactcatt tcattacctc ctctaataag caattatttt aaggaaaact
     1981 ataaagatat agtcgccgat aaaatagcgt ggtcggggaa accgacttta ttttgataat
     2041 caggattttc taagaatctc caagaataac acacattaga aataggaatg tttcctataa
     2101 tatggtctaa tttacaatat ttccaagagt tctcctcaga cggagtatgt acagttaaac
     2161 ctgctttatt catttctgat tttagtaatg gataggagta aaattctcta ggtttacctt
     2221 gataggaatg agtatcatca ttctgcttga aaaagccatt attaaagtca cctagaataa
     2281 ttgtgttttc atgaattggt aaattgaaga ttagcttgtc tagttgtgtt tttctgtgtt
     2341 tgaaatcttc aaaaacattt tcccctccta tcttgatacg aactccaata atgtttaatt
     2401 cttgtccttc aattgtcact ctaacgtgta aaaagtttgg attattatca tcattatcga
     2461 tagtaatgac ttggcaatca ttaactaaat cactctttat tgcaataaga atttcatttc
     2521 caaaatctat agtacgcaca tcttcaaaga ttgtataacc attagtttga aggctagaac
     2581 agaattgaga atgattatct gtttttacat actctgtcag acagataata tctgaatttt
     2641 gctgagctag ttcctgcgca atcatttcag gaatttgttt tccttttctt gaacgtagat
     2701 ttatattcca agtggatgct gtaagttgta tcataaaatt tcctcctaaa agttagtccg
     2761 caggaggagg cacctcctcc tgctatcctt cgaatccatc aaagatttct cctagttcgt
     2821 cttcatcata gtagctttcc aattcctcat agaagtaatc taaggcttct tggtcaaaaa
     2881 agttcattgc tattcctcct ttcagtattt ttttgtacat tttaattgta caaaattaaa
     2941 agaagaaagt aaacaaaaaa gtatacttta atttccaaaa tgtacaaatt taataaaaaa
     3001 aagaatgagt ctgggacaaa aagattttga ttttaggaat tctttattat aaattttaaa
     3061 aatcgataga ttatacaaaa aagcgaacaa gacagaattc tgagtatcag ataactcgtt
     3121 ttgttcgctt tttatattta agattagact tttgttccag actcatttta taaaattatt
     3181 tttgaaattc catatggtat cagaaagtaa tttgtggttg actggtgcaa cgatttcaag
     3241 aagctgtttt tctagaatag agaatttctt gtcaaaatct ttttcaggtt ctgaaatatc
     3301 gtgatttaat tgggtcatca attctgcttt aagaagaaat ttaacacata cacctaaagt
     3361 tacactttga gtatttgtgg cactaggcaa tatttcttta tattttttaa ttccttctgc
     3421 tacttcatcg gacagtgcaa cgttcaattt taattccttt tcttccactg gataaatatt
     3481 ttttaaagag atagagttat cttgtacaac ttttgtccag tttgttacag tctttgaatt
     3541 ttgaaacgca cgcgttaaaa tggtagcttt agttatattg ataccttctg aagtttcata
     3601 tttctctttt agcattctta aatagtaagc tgcttcacca gatattcgga cttgaaattg
     3661 tgtcattatt agtacctccg tattgtatta taccatttgt acattaaaag gacaatgtat
     3721 aaacgaataa tctaccttct cgttcaagca tttttacaag tttagtaatc ttgttgaaga
     3781 tgcattccat gtgttacgtt taaaaaaggg aattaaagta atctagttcc taaaaggtta
     3841 ctaaaaataa aaaaactatc gtttttgtga tagaggtaac tttttgaaaa ggctatttga
     3901 ctggctttat atacttatga aatgttaaga gcccaactca aaatccagtg tccgcaagga
     3961 cgtgccggtt cgaccccggc cgccggtata gtatagtgtt aggaacgttg ttattcttcg
     4021 ttcctttttt atattatttt tggtataatt atagttattc aaattttatt tagattaaga
     4081 aagtgtaggg gagtatgtct tgttctatcg atttattaaa acatcggtat ttgaaaaata
     4141 ttaaagaaaa tcctgaattg tttgtcggaa ttgagttgga gtatcctgtt gcaagtttag
     4201 aaggggatgc tacagatgtt gaagttataa aggatctatt tcattattta gtttctactt
     4261 tggatctcac cgtagcaaag atagatgatt ttggcaatct gatccagtta gtagatccga
     4321 taagtcagga tgctatttta tttgaagttt cctatacaac gattgagttt gcatttggta
     4381 aggctgaaac gattcaagag gtcgaaaatc gtttcaataa ttatatgaat gtaattcaga
     4441 gaaagttagc tgaatcaaat catgctattg ttggctgtgg tatccatccc aactgggata
     4501 aaaatgagaa ttgtccagtg gcttatccac gctatcagat gttgatggat tatttgaatt
     4561 tgagtagaaa tattattaaa tcagatttac atcatttccc tgaatatggt acttttatct
     4621 gtgggagcca ggttcagctg gatatttcaa aaaccaacta cttacgggtg attaatgctt
     4681 ttactcaaat tgaagcggct aaggcttatt tatttgcaaa ctctgagttt tcgggtgcgg
     4741 attgggatac gaaaatttca agggatattt tctgggaaga atctatgcat ggtatctatc
     4801 cagagaatgt tggggtcaat gctagactcc ttaatgatga agctgatttt tttgactatc
     4861 taaatcattc tgcgattttt actgcggaac gtgatgggca gacctattat ttttatccta
     4921 ttcaggctgg ggactatttg gctacgcctg aaatccaagc attttctctg aatggggatg
     4981 aggttattat ttacccccaa gagaaggatt ttgaaactca tcgtagttac cagtaccaag
     5041 acttaacgac tcgaggaaca gttgagtttc gtagtgtgtg tacacagcca cttgatagaa
     5101 cttttgcttc tgcagctttt cacttgggat tattggttaa tttagacaag ttagaagctt
     5161 acttagaaac agcacctttc tttaaagtat ttggttatga ttacaagtct ttaaggagac
     5221 aattttctaa gaaaaatctt acagatgagg aagaaactac gattattgaa ttttccaaag
     5281 acttactcct actagctgag gagggactag tggtgagaaa taaggaagaa atgacctatt
     5341 tacagccttt gagagaagaa ttgagcctat aatttctctt ataaagggag aattttctga
     5401 aaaatcatga tataatggac gagactatag ataaaggata gagagtaatg acattagttt
     5461 atcaatcaac gcgtgatgcc aacaatacag taactgccag tcaagcaatt ttgcaaggtt
     5521 tggcgacgga cggcggtttg tttacaccgg ttacttatcc aaaggtagat ttggactttg
     5581 acaaattgaa agatgcttct taccaggaag ttgctaagct agttttgtca gcatttttag
     5641 atgactttac agctgaggag ttggactact gtatcaacaa tgcctacgat agcaaatttg
     5701 atactccagc tattgcacca ttagtgaaat tagatgggca atacaatttg gaacttttcc
     5761 atggttcaac gattgccttt aaggatatgg ccttgtctat tttgccatac tttatgacga
     5821 ctgctgctaa gaaacatggt ttggagaaca agattgttat cttgacagcg acatctggtg
     5881 acacggggaa agctgctatg gcggggtttg cggatgtgcc tggtactgag attatcgtct
     5941 tttatccaaa ggatggtgtc agcaagattc aagagttaca aatgaccact cagactggcg
     6001 acaatactca tgttattgct attgatggta actttgacga tgcgcaaaca aatgtgaagc
     6061 acatgtttaa cgatgtggct cttcgtgaaa aattgactac caacaagttg caattttcat
     6121 cagctaactc tatgaacatt ggtcgtctgg tgccacaaat tgtttattat gtttatgctt
     6181 acgctcaatt ggttaagact ggtgaaactg tagctggtga aaaggttaac ttcacagtac
     6241 caacaggaaa ctttggaaat atcttggctg ccttttatgc caaacaaatt ggtttgccag
     6301 ttggtaaatt gatctgtgct tcaaatgaca acaatgtttt gacagacttc tttaaaacac
     6361 gtgtctatga caaaaaacgt gagtttaagg taacaaccag cccatctatg gatatcttgg
     6421 tatcttcaaa cttggagcgc ttgattttcc atcttttggg aaataatgct gaaaagacag
     6481 ctgaactcat gaatgctttg aacatgcaag gacaatataa gttgacagac tttgatgcag
     6541 agattttgga cctctttgca gctgaatatg cgactgagga agaaacagcg gcagaaatca
     6601 agcgtgttta tgagttagat tcttatattg aggatccaca tacggcggtt gcctcagcag
     6661 tttatagaaa ataccaagcg gttactgatg atgcgactaa gacagtgatt gcttcaacag
     6721 ctagtcccta caagttccca gtagttgcag tagaagctgt aactggaaaa gcaggtttaa
     6781 cagactttga agctttggct caattacatg aaatctcagg cgttgcagtg ccaccagcag
     6841 ttgatgggct tgagacagct cctgttcgtc acaagacaac agtggcagct gctgacatgc
     6901 aagtagcggt tgaggcttat ttaggacttt aagatagagg gagtaaactc ggttgggaaa
     6961 ccaactgagt ttcttttcat caggaggaga gattgtttaa gaaaaataaa gacattctta
     7021 atattgcatt gccagctatg ggtgaaaact ttttgcagat gctaatggga atggtggaca
     7081 gttatttggt tgctcattta ggattgatag ctatttcagg ggtttcggta gctggtaata
     7141 ttatcaccat ttatcaggcg attttcatcg ctctgggagc tgctatttcc agtgttattt
     7201 caaaaagcat agggcagaaa gaccagtcga agttggccta tcatgtgact gaggcgttga
     7261 agattacctt actattaagt ttccttttag gatttttgtc catcttcgct gggaaagaga
     7321 tgataggact tttggggacg gagagggatg tagctgagag tggtggactg tatctatctt
     7381 tggtaggcgg atcgattgtt ctcttaggtt taatgactag tctgggagcc ttgattcgtg
     7441 caacgcataa tccacgtctg cctctctatg ttagtttttt atccaatgcc ttgaatattc
     7501 ttttttcaag tctagctatt tttgttctgg atatggggat agctggtgtt gcttggggga
     7561 caattctgtc tcgtttggtt ggtcttgtga ttttgtggtc acaattaaaa ctgccttatg
     7621 ggaagccaac ttttggttta gataaggaac tgttgacctt ggctttacca gcagctggag
     7681 agcgacttat gatgagggct ggagatgtag tgatcattgc cttggtcgtt tcttttggga
     7741 cggaggcagt tgctgggaat gcaatcggag aagtcttgac ccagtttaac tatatgcctg
     7801 cctttggtgt cgctacggca acggtcatgc tgttggcccg agcagttgga gaggatgatt
     7861 ggaaaagagt tgctagtttg agtaaacaaa ccttttggct ttctctgttc ctcatgttgc
     7921 ccctgtcctt tagtatatat gtcttgggtg taccattaac tcatctctat acgactgatt
     7981 ctctagcggt ggaggctagt gttctagtga cactgttttc actacttggg acccctatga
     8041 cgacaggaac agtcatctat acggcagtct ggcagggatt aggaaatgca cgcctccctt
     8101 tttatgcgac aagtataggc atgtggtgta tccgcattgg gacaggatat ctgatgggga
     8161 ttgtgcttgg ttggggcttg cctggtattt gggcagggtc tctcttggat aatggttttc
     8221 gctggttatt tctacgctat cgttaccagc gctatatgag cttgaaagga taggaaatgc
     8281 aaaaaacagc ttttatttgg gatttagacg ggactttatt ggactcttac gaagcgattt
     8341 tatcagggat tgaggagact tttgctcagt tttctattcc ttatgataag gagaaggtga
     8401 gagagtttat cttcaagtat tcggtgcaaa atttgcttgt gcgggtggca gaagatagaa
     8461 atctggatgt tgaggtgcta aatcaggtgc gtgcccagag tctggctgag aagaatgctc
     8521 aggtagtttt gatgccaggt gcgcgtgagg tgctagcttg ggcagacgaa tcaggaattc
     8581 agcagtttat atatactcat aaggggaaca acgcttttac cattctcaag gacttggggg
     8641 tggaatccta ttttacagag attttaacca gtcagagtgg ctttgtgcgg aagccaagtc
     8701 cagaagcggc tacctatctg ctagataagt atcagctgga tcctgagaag acctattata
     8761 taggggaccg gactttagat gtggaatttg ccaagaatag cggtattcaa agcatcaact
     8821 ttttagaatc ttcttttgaa ggcaatcaca ggattcaagc actagcagat atttcccgta
     8881 tttttgagac taagtgataa aaagattgtg tcagttttgt gacagagacc taacaaacta
     8941 tttcaagtaa tctagtttgt tacaaggaat agacagttct gttaaatagg cccgagaggg
     9001 ctttttttct acattttttg tgttatgata gacaggtact catttgaaag gaatttgaaa
     9061 gaatgaagaa aagaatgtta ttagcgtcaa cagtagcctt gtcatttgcc ccagtattgg
     9121 caactcaagc agaagaagtt ctttggactg cacgtagtgt tgagcaaatc caaaacgatt
     9181 tgactaaaac ggacaacaaa acaagttata ccgtacagta tggtgatact ttgagcacca
     9241 ttgcagaagc cttgggtgta gatgtcacag tgcttgcgaa tctgaacaaa atcactaata
     9301 tggacttgat tttcccagaa actgttttga caacgactgt caatgaagca gaagaagtaa
     9361 cagaagttga aatccaaaca cctcaagcag actctagtga agaagtgaca actgcgacag
     9421 cagatttgac aaccaatcaa gtgaccgttg atgatcaaac tgttcaagtt gcagatcttt
     9481 ctcaaccaat tgcagaagct ccaaaagaag tagcatcaaa ttcagaagtt gcagagacag
     9541 tgactgctgc agaagaagtg gcaccatcta cgggcacttc tgtcccagag gagcaaacgg
     9601 ccgaaacaac tcgcccagtt gaagaagtag ctcctcaggc aacgactcta gctgagaagc
     9661 aggaaacaca agtgagctct caaaccgagt cagcagtgga agcaactaca atgccagtag
     9721 aagaaaaagc aaccgaaaca actgcaacaa gttcagaagc aaaagaagta gcatcatcaa
     9781 atggagctac agcagcagtt tctacttatc aaccagaaga gacgaaaaca atttcaacaa
     9841 cttacgaggc tccagctgcg cccgattatg ctggactggc agtagcgaaa tctgaaaatg
     9901 caggtcttca accacaaaca gctgccttta aagaagaaat tgctaacttg tttggcatta
     9961 catcctttag tggttatcgt ccaggagaca gtggagatca cggaaaaggt ttggctatcg
    10021 actttatggt accagaaagt tcagaattag gggataagat tgcggaatat gctattcaaa
    10081 acatggccag ccgtggcatt agttacatca tctggaaaca acgtttctat gctccattcg
    10141 atagcaaata tgggccagct aacacttgga acccaatgcc agaccgtggt agtgtgacag
    10201 aaaatcacta tgaccacgtt cacgtttcaa tgaatggata aacccgactt ggtaacatca
    10261 ttttgacgaa tgagatctag ctttcgtgat aggaagcgat tctcgttcgt tttttctttg
    10321 tcatactctt cgaaaatctc ttcaaacaac gtcagtttta tctgaaacct caaagctgtg
    10381 ctttgagcaa cctgcgacta gcttcctagt ttgctttttg attttcattg agtatcaatt
    10441 tgaatggaaa atggaaagtt atcatcttgt aatgagttaa gcaacattct tgcaatctat
    10501 tttatagtag attgaaacta gaatagtaca caactgcttc taaaacattg ttagaaatcg
    10561 atttgactgt cctgatcgat ttgtcctgct cttatttcat ttcactatac tttatattat
    10621 aattgactgg tcaaatattg ataaatcaat aaaaagagag gggaagaaat gctagagatt
    10681 caagatttac tgtatcaact ccgcttgtct gagcaagtga gtacgcaatt gtttgaaaaa
    10741 gcttgggatt agtttgacac ggtatcagat tttactgttt ttgctggagc attctctttg
    10801 taaccaaatg gcggttcagg agcgtttgaa aattgatcag gctgctttga cacggaattt
    10861 caagattttg gaaacggaag gtttggtgga gcgtcatcgt aatcctgaaa atcagcggga
    10921 agtattggta gaggctgcga agtatgccaa ggagcagtta gtggtgaatc cccctctgca
    10981 acatatcaag gttaaggaag agatggaaag tatcttaaca gagtttgaga gaacagaact
    11041 cagccgttta ttaaataaat tggttttggg tattgaaaat atagaaattt aaggagaaat
    11101 agatgtcaat tattacaatt attttaacaa cgatcgttgc ttgggagcat ttttacattt
    11161 tttatttaga aagtattgcc acgcaatcag atgcgactag tcgtgtattt aatatggaaa
    11221 gggaagaatt ggctcatccg tcagtaagtt tattgttcaa aaatcaaggg atttataagg
    11281 ctctgctagg agtctgtctc ttgtatggca tttatttctc acagaattta gaaattgtga
    11341 ctatttttgt cttatttgtg attggtgctg cgacttacgg ctctttaaca gcggataaaa
    11401 aaattatttt gaaacaaggt ggatcagcta ttttggcctt gattagtatt ttactcttta
    11461 aatacacttg aaggtcgatt ctaatctcgc taatcctttt taatccagaa taagggaaat
    11521 atgttatact tgtttttaag aaaaaagttt cattgaattg gttttgagga gttagaaatg
    11581 aaagtattag tgacaggttt tgagcccttt tgaggccatt aaaggtttac cagctgaaat
    11641 ccatggtgct gaggtccgtt ggctagaggt gccgacagtt tttcacaaat ctgctcaagt
    11701 attggaagaa gagatgaatc gttatcaacc tgactttgtc ctttgtattg ggcaagctgg
    11761 tggaagaact agtttgacac ctgaacgagt ggccattaat caagacgatg cacgtacttc
    11821 tgataacgaa gataatcaac cgattgaccg tcccattcgc ccagatggtg cttcggccta
    11881 ctttagtagt ttgccgatta aagcgatggt tcaagctata aaaaaagagg gcttaccggc
    11941 ctctgtttcc aatacggcag ggacttttgt ctgcagccat ttgatgtatc aggctctcta
    12001 tttggtagaa aagaaatttc catatgttaa ggcaggtttt atgcatattc cttatatgat
    12061 ggaacaggtg gtgaacagac cgactactcc agctatgagt ttagtggata ttcggcgagg
    12121 gatagaagca gcaatcggcg ctatgataga acatggagat caggaactca agttggtagg
    12181 cggagaaact cattgataga aaaaagcttg aggggaaaaa ccttcaagct tttggacgtt
    12241 ttcgagccaa tactgctcgg taaaacataa ttttagtgca ttggatataa ggtaggagtg
    12301 aaaaactagc aatgccaaag gtaatccaat tgaggaagta ccaaggaaga agctgtaaat
    12361 ctaggacaaa gcgctggaac ttgtagccct tcataaagga acggctagtt tttaggattc
    12421 gtcttggtgg gacctgtcct aggtctagac tataacagag aagaaattcc acctgtgaat
    12481 aggcataata ctgtggaata tagaggatat ttcctacaat gatcaagatg agacttgcaa
    12541 gaaagtagag tccaaagacc atgaggaaac gctcggtttc aactgatgag agatctagat
    12601 ttggaaactc aggatgtagg gtgacgaatt ttttggctaa aaagctacta taaaagagga
    12661 ggtaaatccc aagtaaatta gggatactcc ataaaaagag atagaaacgt ttgagaagta
    12721 gggtcaaaaa ggtttgagaa aagcgctcct catcaaagag agctaggctg ttttttacag
    12781 atggctccgt tttagaatct ttcatgagtg tcagtgttgc atagacggaa ctggtcaaaa
    12841 gaatagtccc gataaaggag actagtagag gaaagaggta ggtttgaagt atttggccaa
    12901 gtatgctgaa aaatggctgt tctaaaacag tcccgtggat ccgagataag ggattaagaa
    12961 aactagataa gatgaccagc atactgggaa ggatatagag gagaaagaga cggggggtgt
    13021 cagcctgaaa atgttttgac tcctgacgaa ttgtttttaa atcaattttt ggatagttca
    13081 ttctcttatt ataccatagt tcttatacat agttcgtgac agttcctact ttttttgata
    13141 aaatcataca gtgtgtcctt gggcacactg tatgaactgg gactgtcttt cccagcttcg
    13201 gaggtaaaaa atgtcagatt caccaatcaa atatcgtttg attaagaaag aaaaacacac
    13261 aggagctcgt ctaggagaaa tcatcactcc ccacggtacc tttccgacac ctatgtttat
    13321 gccagttggg acacaagcca ctgtcaaaac tcagtcacct gaagaattga aggagatggg
    13381 ttcgggaatt atcctatcaa acacctatca tctctggctt cgccctggag atgaactcat
    13441 tgcacgcgct ggtggtctcc acaagttcat gaattgggac cagcctatct tgacagatag
    13501 tggtggtttt caggtttatt ctttagcaga tagccgtaat atcacagaag aaggagtaac
    13561 ctttaaaaat catctaaatg gttctaagat gctcctatcc ccagaaaaag ccatctctat
    13621 tcagaataat ctgggttcag acatcatgat gtcctttgat gaatgtcctc agttttatca
    13681 accttatgac tacgttaaga aatcgatcga gcgtaccagc cgttgggctg agcgtggttt
    13741 gaaggctcac cgtcgtccac atgaccaagg tttgtttgga attgtgcaag gtgcaggatt
    13801 tgaagacctt cgccgccaat cagctcatga tcttgtcagc atggatttct caggctactc
    13861 tatcggtggt ttggcagtgg gagaaaccca tgaagagatg aatgcggtct tggactttac
    13921 aactcaactg ctgcctgaaa ataaacctcg ttatctgatg ggtgtgggag cgccagatag
    13981 cttgatcgat ggggtcattc gtggggtgga tatgtttgac tgtgtcttac cgactcgaat
    14041 tgctcgtaac gggacttgta tgaccagtca aggacgtttg gttgtgaaaa atgcccagtt
    14101 tgctgaggac tttacgccac tggatcctga gtgtgattgc tacacatgta ataactatac
    14161 acgcgcttac cttcgtcacc tgctcaaggc tgatgaaacc tttggtatcc gcttgactag
    14221 ctaccacaat ctttacttct tgcttaacct gatgaagcaa gtgcgacaag ccatcatgga
    14281 tgacaatctc ttggaattcc gtaagtattt tgtggaaaaa tatggctata ataagtcagg
    14341 acgtaatttc taaaatggaa ttgatataag ctaaaaatcc taagttttct cttaggattt
    14401 ttcttctttt tttgatagaa taaagtgtac aatgaaagga agaataaact cgtatgcgca
    14461 ttaaatggtt ttccttggtt aggattacag gtttactttt ggtactcttg tatcacttct
    14521 ttcagacgat ctttcctgga ggatttttcg gggtagatgt ctttttcaca ttttcaggtt
    14581 tcctgattac agctctactc attgaagaat tttctaaaaa ccatgagatt gatttgatag
    14641 gattttttag aagacgcttt tatcggattg tgccacctgt ggttttgatg gtcttggtga
    14701 ccatgccttt tactttcttg gttcgccaag actatgttgc tggaattggt ggccagattg
    14761 cgagcgtctt aggctttatg accaacttct atgaactcct aacaggtggg agttatgaat
    14821 ctcagttcat tcctcatttg tttgttcata attggagttt ggcagttgag gttcactact
    14881 atattctttg gggattggca gtttggttct tatccaaaca agctaaatca aatggtcagt
    14941 tgaaggggat ggtctttctc ttatctgctg ttgccttctt gatcagtttc ttctccatgt
    15001 ttattggtag ttttctagtg acctcttatt cctctgttta tttctccagt ttaactcatg
    15061 tctatccatt ctttttggga agtatgttag caactattgt aggcgttcgt cagacgactt
    15121 ccctcgtcaa gcagttggat aaaatctggg atttacgaaa gactttggta gtttttggag
    15181 gaggctttgg tttcctagtt cttttgactt tctttgtcaa attcacttat ctttttgcct
    15241 atcttatcgg cttcttactt gccagtcttg cagctcttgc catgattctg gcggcgcgtg
    15301 tcttacatga aaagacacat catatacagg agccgaagat tatcagcttt ttagcggata
    15361 ctagctatgc ggtttatctt ttccattggc ctttctatat cattttctca cagttgacat
    15421 caaatcttct tgctgtatta ctgactctga tttgttctta tggctttgcc agtctgtcat
    15481 tctatgtatt ggaaccttgg attgcaggca agaacacacc tattgtccaa acccttcgtc
    15541 ccctgcctta tattcacgca attcttgcag caggtacagg aatcttgacc atcattgtct
    15601 gcacggtgac cttgttggca ccacaagtgg gagcgtttga gacagacttg actgtcaatg
    15661 gcttgaagca agctgcaaca aatattggcc agaccaaggt gatggcagaa cgggcagatg
    15721 caaacagttt gggaattgct gatggcacta tgttaattgg tgactcagtg gctttaaggg
    15781 caaatacagc actacagaca gctcttcctg gagcacagat taacgcgcag gtcagcgtaa
    15841 caaccaagac cgcaaatgaa atcatgctaa ataatagcca gaataaattt ttacctaaga
    15901 cggtggtcat tgcgactggg gtaaataatc ctgagaatta caaggatgac tgggacagta
    15961 tcgtgaaaaa tcttcctaag ggacaccata tgattttggt gactccttat gagggagata
    16021 agacaaaaga gacctatgcc atcgttgaga aggctgctgc ctatatgaga gaattggcag
    16081 agaagacacc ttacattacg atagcagatt ggaatcaagt tgcgaaagag catccagaaa
    16141 tttgggcagg aacagaccag gttcatttcg ggagtgagag tagcactatc gaagcaggag
    16201 caaaattgta tgcagatacg attgccacag ctttgcagac agctcaagac aagccggtta
    16261 aatcaaaata acttgtatta aaaaagagaa gagttggaga aatccagctc ttttaaaata
    16321 tctccaaaaa ataggtctat accatttaca aataaaaaag aaaggtttat aatgtaattg
    16381 acataataaa ttgtagaatc aatcttttaa ggaggttaac attatgccta actatattaa
    16441 agcggatcag tttttctacc cacacggagt tcgtcgaggt ggttacttgg aacttgtgga
    16501 cggcaagttt gggaaacatg tagagcagat tcctgaaggg gctgaggtga ttgactatac
    16561 aggttatagc attgccccag gtcttgtgga tactcatatt catggatatg caggtgtaga
    16621 tgtgatggac aacaacattg aaggtacatt gcatactatg agtgaaggac ttcttagtac
    16681 cggtgttacc agtttcttac ccacaacttt aacagccact tatgagcaat tgcttgcagt
    16741 cactgaaaat cttggaaacc attataaaga agcaacaggt gctaagattc gtgggattta
    16801 ttatgaaggt ccatatttca cagaaacttt taagggggca caaaatccaa cttatatgag
    16861 agacccgggt gttgaggagt ttcattcttg gcaaaaagcg gcaaatggct tgcttaataa
    16921 aattgccctt gcaccagaac gtgatggggt ggaggacttt gttcgtacag ttacgggcga
    16981 aggtgtgacg gttgctcttg gacattcaaa cgcgactttt gatgaagcca aaaaagcagt
    17041 cgatgctgga gcgagtgttt gggtgcatgc ctacaatgga atgcgtgggt tgactcaccg
    17101 tgaattgggt atggttggag ccatgtacca attgccacat acctatgcag agttgatctg
    17161 tgatggccac cacgtagatc caaaggcttg cgaaattctt atcaaacaaa aaggaacaga
    17221 aaacatcgct cttatcacag actgtatgac agctggggga ttggaagacg gagattatat
    17281 gttgggagaa ttcccagttg tcgttgcaaa tggaactgca cgcctcaaat cgacaggtaa
    17341 cttggcaggt tctatcctca aactcaaaga tggtttgaag aatgtggtcg aatggggaat
    17401 tgcgaatccg catgaagcag tcatgatggc cagcttcaac ccagctaaat ccgttcacat
    17461 cgatgatgtc tgtggccaaa tccgtgaagg ctacgacgct gacttcatcg tattagataa
    17521 agatttggaa ttggtagcaa cctacctaga tggcgtaaaa cgttatcaag cataagagag
    17581 aaagcagaag ttagagacta acttctgctt ttttatgcag ggtactttac tggtaaataa
    17641 aaagttaaaa aaatcacaaa aaaagcttga agaaacaaag aaaaaggctt acaattgaac
    17701 tataaatatt acaaataaaa aaacggagga gtgctttatg aaagcctata cttatgttaa
    17761 accaggactt gcttcttttg ttgatgtaga caaaccagtt attcgcaagc caacagatgc
    17821 tattgtgcgt attgtaaaaa ccactatttg tggaacagac ctccatatta tcaaagggga
    17881 tgttcctact tgccaaagtg gtaccattct tggccacgaa gggattggga ttgttgaaga
    17941 agttggggaa ggagtttcca acttcaaaaa aggtgacaag gtcttgattt cttgcgtctg
    18001 tgcctgtggt aaatgctact actgtaaaaa aggaatttat gctcactgtg aagacgaagg
    18061 gggctggatt ttcggtcact tgattgatgg tatgcaggct gaatatctac gtgtccctca
    18121 tgcagataat actctttacc atactccaga agacttgtca gatgaagctt tggttatgct
    18181 gtcagacatt ctgcctactg gatatgaaat tggtgtctta aaagggaaag tagaacctgg
    18241 ttgcagcgta gccattattg gttcaggtcc agttggattg gctgctcttt taacagccca
    18301 attctattca ccagctaaat tgattatggt agacctagac gataaccgct tggaaactgc
    18361 cctatcattc ggtgcgactc ataaggttaa ttcttcagac cctgaaaaag ccattaaaga
    18421 aatttatgat ttgacagatg gtcgtggtgt ggatgtcgct atcgaagctg ttggtattcc
    18481 tgcaacattt gatttctgtc aaaagattat cggtgtagac ggaacggttg ccaactgtgg
    18541 tgtgcatggt aaaccagttg aattcgattt agataaactt tggattcgca acatcaatgt
    18601 aacaactggt ttggtatcta caaatacgac tccacaattg ttgaaagcac ttgaaagtca
    18661 taagattgaa ccagaaaaat tggtaactca ctatttcaaa ctcagtgaaa ttgaaaaagc
    18721 ctatgaagtc ttcagtaagg cagcagacca ccatgccatt aaggtcatta tcgaaaacga
    18781 tatctcagaa gcctaagtag taaaaatatt tttgtacata agtaaataga aattcagtca
    18841 tccatcagat ggctggattt tttatcaaaa aattaagaaa tgagcatatt tctttccttg
    18901 tctggcggaa ttggttataa tatacggtac aaaggaatga atgaatatgt atcgtgttat
    18961 agaaatgtac ggagattttg aaccgtggtg gttcttagaa ggttgggaag aagatattgt
    19021 agcaagtaga aaatttgacc agtattatga tgctctcaaa tactacaaaa cttgctggtt
    19081 tagattggaa caagaatccc ctctttataa aagtagaagc gacttgatga ccattttttg
    19141 ggacccggaa gaccaacgct ggtgtgatga atgtgatgag tatttacaac aataccattc
    19201 tttggctctt ttgcaggatg agcaggttat cccagacgaa aaactacgct caggctatga
    19261 aaaacaaacc agtcaggaaa ggaatcgttc ttgccgtatg aaattaaaat agagaaaagt
    19321 aacttttttg gagttgcttt ttttattttt ctaacgcttt gcgaatagta taggtgagga
    19381 ggtaagtatg gttcaagaaa ttgcacaaga aatcattcgt tcagctcgga aaaaagggac
    19441 gcaggatatt tattttgtcc ctaagttaga cgcctatgag cttcatatga gggtaggaga
    19501 cgagcgctgt aaaattggta gctatgattt tgaaaagttt gcagccgtta tcagtcactt
    19561 taagtttgtg gcgggtatga atgtgggaga aaaaagacgt agtcaactgg gttcctgtga
    19621 ttatgcctat gaccagaaga tggcgtctct acgtttatct actgtaggcg attatcgggg
    19681 acatgagagt ttggttatcc gtttgttgca cgatgaggag caggacttgc atttttggtt
    19741 tcaggatatt gaagaattag gcaagcagta caggcaacgg ggactctatc tttttgctgg
    19801 cccggttggg agtggtaaga cgaccttgat gcatgaattg tccaagtcac tctttaaagg
    19861 acagcaagtt atgtccatcg aagatcctgt cgaaatcaag caggacgaca tgcttcagtt
    19921 gcagttgaac gaagcaatcg gcctaaccta tgaaaatcta atcaaacttt ccttgcgtca
    19981 tcgaccagat ctcttgatta tcggagaaat tcgtgacatc gagacggcgc gtgcagtggt
    20041 cagagctagt ttgacaggtg cgacagtctt ttcaaccatt cacgccaaga gtatccgagg
    20101 tgtttatgag cgtctgctgg agttgggtgt gagtgaagaa gaattggcag ttgttctgca
    20161 aggagtctgc taccagagat taatcggggg aggaggaatc gttgactttg caaacagaga
    20221 ttatcaagaa caccaagcag ccaagtggaa tgagcaaatt gaccagcttc ttaaagatgg
    20281 acatatcaca agtcttcagg ctgagacgga aaaaattagc tacagctaag caaaaaaata
    20341 tcatcaccct atttaacaat ctcttttcta gcggttttca tctggtggag actatctcct
    20401 ttttagatag gagttccttg ttggacaagc agtgtgtgac ccagatgcgt acaggcttgt
    20461 ctcaggggaa atcattctca gaaatgatgg aaagtttggg atgttcaagt accattgtca
    20521 ctcagttatc tctagctgaa gttcatggca atcttcacct gagtttggga aagatagaag
    20581 aatatctaga caatctggcc aaggtcaaga aaaagttaat tgaagtagcg acctatcctt
    20641 tgattttgct gggttttctt ctcttaatta tgctggggct acggaattac ctgctcccac
    20701 aactggatag tagcaatatt gccacccgaa ttatcggtaa tctgccacaa atttttctag
    20761 gcatggtagg gcttgtttcc gtgcttgccc ttttagcact aactttttat aaaagaagtt
    20821 ctaagatgag tgtcttttct atcttagcac gccttccctt tattggaatc tttgtgcaga
    20881 cctacttgac agcctattat gcacgtgaat gggggaatat gatttcacag ggaatggagc
    20941 tgacgcagat ttttcaaatg atgcaggaac aaggttccca gctctttaaa gaaatcggtc
    21001 aagatctggc tcaaaccctg aaaaatggcc gtgaattttc tcagacgata ggaacctatc
    21061 ctttctttag gaaggaattg agtctcatca tagagtatgg ggaagttaag tccaagctgg
    21121 gtagtgagtt ggaaatctat gctgaaaaaa cttgggaagc cttttttacc cgagtcaacc
    21181 gtaccatgaa tttggtgcag ccactggttt ttatctttgt ggcactgatt atcgttttac
    21241 tttatgcggc aatgctcatg cccatgtatc aaaatatgga ggtaaatttt taaaatgaaa
    21301 aaaatgatga cattcttgaa aaaagctaag gttaaagctt ttacattgat tgagatgttg
    21361 gtggtcttgc tgattatcag cgtgcttttc ttgctctttg tacctaatct gaccaagcaa
    21421 aaagaagcag tcaatgacaa aggaaaagca gctgttgtta aggtggtgga aagccaggca
    21481 gaactttata gcttagaaaa gaatgaagat gctagcctaa gaaagttaca agcagatggg
    21541 cgcatcacgg aagaacaggt taaagcttat aatgaatact atactaaaaa tggaggggca
    21601 aatcgtaaag tcaatgatta aggcctttac catgctggaa agtctcttgg ttttgggact
    21661 tgtgagtatc cttgccttgg gcttatccgg ctctgtccag tccacttttg cagcagtaga
    21721 ggagcagatt ttctttatgg agtttgaaga actctatcgg gaaacccaaa aacgcagtgt
    21781 agccagtcag caaaagacta gtctaaattt agatgggcag acgcttagca atggcagtca
    21841 aaagttgaca gttcctaaag gaattcaggc accatcaggc caaagtatta catttgaccg
    21901 agctgggggc aattcgtccc tggctaaggt tgaatttcag accagtaaag gagcgattcg
    21961 ctatcaatta tatctaggaa atggaaaaat taaacgcatt aaggaaacaa aaaattaggg
    22021 cagtgatttt actggaagca gtagtcgctc tagctatctt tgccagcatt gcgaccctcc
    22081 ttttgggaca aattcaaaaa aataggcaag aggaagcaaa aatcttgcaa aaggaagaag
    22141 tcttgagggt agctaagatg gccttgcaga caggtcaaaa tcaggtaaac ataaacggag
    22201 ttgagattca ggtgttttct agcgaaaagg gattggaggt ctaccatggt tcagaacagt
    22261 tgttggcaat caaagagcca taaggtcaag gcttttacct tgttagaatc cctgcttgcc
    22321 ctgattgtca tcagtggggg cttactcctt tttcaagcta tgagtcagct cctcatttca
    22381 gaagttcgct accagcaaca aagcgagcaa aaggagtggc tcttgtttgt ggaccaactt
    22441 gaggcagaat tagaccgttc gcagttcgaa aaagtagaag gcaatcgcct atacatgaag
    22501 caagatggca aggacatcgc catcggtaag tcaaagtcag acgattttcg taaaaccgat
    22561 gctagtggac gggggtatca gcctatggtt tatggcctca aatcagctca gattacagag
    22621 gacaatcaac tggttcattt tcgtttccag tttcaaaaag gcttagaaag ggagttcatc
    22681 tatcgtgtgg aaaaagaaga aagttaaggc aggtgttctc ctctacgcag tcaccatagc
    22741 agccatcttt agtcttttgt tgcaatttta tttgaaccga caaatcgccc actatcaaga
    22801 ctatgcttta aataaagaaa aattggttgc ttttgccatg gctaaacgaa ccaaggataa
    22861 agccgagcaa gaaagtgggg aacaggtttt taatctaggt caggtaagct atcaaaacaa
    22921 gaaaacaagc ttggtgacga ctgttcgtac gtctaagagc caatatgagt ttctgtttcc
    22981 ttcagtcaaa atcaaagaag agaaaagaga taaaaaggaa gaggtagcga ccgattcaag
    23041 cgaaaaagcg gagaaaaaaa atcagaagag aagcctgaaa agaaagagaa ttcctagtca
    23101 attcaactat aatgcgttga atccagaata gtccactgta gtttctagaa aattgctgga
    23161 aatggatgtt aagctccaat tcatttgttt atatcttatt tcagtttact atactttgtg
    23221 ctaaattaaa gatatgaaac atgattttaa ccacaaagca gaaactttcg attcccctaa
    23281 aaatatcttc ctcgcaaact tggtatgtca agcagccgag aaacagattg atcttctatc
    23341 agacaaagaa attttagatt tcggtggtga cacgggtcta ttagccttgc ccctagcccc
    23401 tagccaagca ggctaagtca gtcactcttg tagacatttc tgagaaaatg ttggagtaag
    23461 ctcgtttgaa agcggagcag caagcaatca agaatatcca gtttttggag caagatttac
    23521 cgaaaaatcc cttggagaaa gagtttgatt gccttgctgt tagtcggctt cttcatcata
    23581 tgcctgattt ggatgcggat ctctcactgt ttcatcaaca tttgaaggaa gataggaaac
    23641 tcatcattgc tgattttacc aagacagaag ctaatcatca tggatttgat ttagctgaac
    23701 tggaaaacaa gctaattgag catggttttt catctgtgca tagtcagatt ctctatagcg
    23761 ctgaagacct gtttcaaggg aatcactcag aattcttttt aacagtatcc caaaaatcac
    23821 tcgcctagtc agggagtgat ttttctataa ggatggaaaa aagaagggaa atttgataag
    23881 ataggaatat ggattttgaa aaaattgaac aagcttatat ctatttacta gagaatgtcc
    23941 aagtcatcca aagtgatttg gcgaccaact tttatgacgc cttggtggag caaaatagca
    24001 tctatctgga tggtgaaact gagctaaacc aggtcaaaga caacaatcag gcccttaagc
    24061 gtttagcact acgcaaagaa gaatggctca agacctacca gtttctcttg atgaaggctg
    24121 ggcaaacaga acccttgcag gccaatcacc agtttacgcc agatgctatt gccttacttt
    24181 tggtatttat tgtggaagag ttgtttacag aggaggaaat tactatcctc gaaatgggtt
    24241 ctgggatggg aattctaggc gctactttct tgacctcgct tgataaaaag gtggattact
    24301 tgggaatgga agtggatgat ttgctgattg atctggcagc tagcatggca gatgtaattg
    24361 gtttgcaggc tggctttgtc caaggagatg ccgttcgccc acaaatgctc aaagaaagcg
    24421 atgtggtcat cagtgacttg cctgtcggct attatcctga tgatgccgtt gcgtcgcgtc
    24481 atcaagttgc ttctagccaa gaacatactt acgcccatca cttgctcatg gaacaagggt
    24541 ttaagtacct taagtcagat ggatatgcta tttttctagc tccgagtgat ttgttgacca
    24601 gtcctcaaag tgatttgttg aaagtctggt tgaaagagga ggcaagtctg gttgctatga
    24661 ttagtttacc tgaaaatctc tttgctaatg ctaaacaatc taagactatt tttatcctac
    24721 agaagaaaag tgaaatagca gtggagcctt ttgtttatcc acttgctagc ttgcaagatg
    24781 caagtgtttt aatgaaattt aaagaaaatt ttcaaaaatg gactcaaggt actgaaatat
    24841 aaaatagatt ttgttataat agttgaaaac gcttaaaaag gggtatcatg ttatgacaaa
    24901 aacaattgca atcaatgcag gaagttcaag tttgaaatgg caattatact taatgccaga
    24961 ggaaaaagtg ttagccaaag gtttgattga acgtatcggt ttgaaagatt caatttcaac
    25021 tgtaaaattt gacggccgtt ctgaacaaca aattttggat attgaaaatc atacacaagc
    25081 cgttaaaatt ttattggatg acttgattcg tttcgatatt atcaaggctt atgacgagat
    25141 tacaggtgtt ggacatcgtg ttgttgctgg tggagaatat ttcaaagaat caacagttgt
    25201 tgagggagat gttttagaaa aagttgaaga gttgagtttg ttggctcctc tacacaaccc
    25261 ggccaatgca gcaggtgttc gtgccttcaa ggaattgttg ccagacatta ccagtgtagt
    25321 tgtttttgat acttccttcc acacaagtat gccagagaaa gcttatcgct accctctacc
    25381 aacaaaatat tacacagaaa acaaggttcg taaatacggt gctcatggta caagtcacca
    25441 gtttgtagca ggagaagctg caaaactctt gggacgtcca ttagaagact tgaagttaat
    25501 tacctgtcat attggtaacg gaggctcaat tacagctgtg aaagccggca aatctgtaga
    25561 cacttctatg gggttcactc ctcttggtgg tattatgatg ggaacgcgta caggggatat
    25621 tgatccagct atcattcctt atttaatgca atatacagag gattttaaca caccagaaga
    25681 tatcagtcgt gttcttaacc gtgaatcagg tcttttggga gtttctgcta attctagcga
    25741 tatgcgcgat atagaagcag ctgtagcaga agggaatcac gaggctagct tggcttatga
    25801 aatgtatgtt gaccgtatcc aaaaacatat cggtcagtac cttgcagtgc taaatggagc
    25861 agatgtcatt gttttcacag caggtgtcgg tgaaaatgca gagagtttcc gtcgtgatgt
    25921 aatctcaggg atttcgtggt ttggttgtga tgttgatgat gaaaagaatg tctttggcgt
    25981 tacaggagac atctcaacag aggcagctaa aatccgtgtc ttggttattc caacagatga
    26041 agaattagtc attgcccgtg acgttgaacg cttgaaaaaa taagtgaaac taaaaaaata
    26101 ttcaatacaa ggagttggga aagttatttt tccagcttct ttttctgatg aaattgtcca
    26161 aaaccttgct atgattggct tttttgaaaa atatggtata atagtagtaa tttaatagat
    26221 ggagttgagt tttgaagaaa aactttcgtg taaaaagaga gaaagatttt aaggcgattt
    26281 tcaaggaggg gacaagtttt gctaatcgca aatttgtggt ctaccaatta gaaaaccaga
    26341 aaaaccattt tcgagtaggt ctatcagtta gcaaaaaact ggggaatgcc gtcactagaa
    26401 atcaaattaa gcgacggatt cggcatatta tccagaatgc aaaagggagt ctggtagaag
    26461 atgtcgactt tgttgtcatt gctcgaaaag gagtcgaaac cttgggatac gcagagatgg
    26521 agaaaaatct actccatgta ttaaaattat caaagattta ccgggaagga aatgggagtg
    26581 aaaaagaaac taaagttgac tagtttgcta ggactgtctc tgttaatcat gacagcctgt
    26641 gcgactaatg gggtaactag cgatattaca gccgaatcgg ctgatttttg gagtaaattg
    26701 gtttacttct ttgcggaaat cattcgcttt ttatcgtttg atattagtat cggagtgggg
    26761 attattctct ttacggtctt gattcgtaca gtcctcttgc cagtctttca ggtgcaaatg
    26821 gtggcttcta ggaaaatgca ggaagctcag ccacgcatta aggcgcttcg agaacaatat
    26881 ccaggtcgag atatggaaag cagaaccaaa ctagagcagg aaatgcgtaa agtatttaaa
    26941 gaaatgggtg tcagacagtc agactctctt tggccgattt tgattcagat gccggttatt
    27001 ttggccctgt tccaagccct atcaagagtt gactttttaa agacaggtca tttcttatgg
    27061 attaaccttg gtagtgtgga tacaaccctt gttcttccga ttttagcagc agtattcacc
    27121 tttttaagta cttggttgtc caacaaagct ttgtctgagc gaaatggcgc tacgactgcg
    27181 atgatgtatg ggattccagt cttgattttt atctttgcag tttatgcgcc aggtggagtc
    27241 gccctatact ggacagtgtc taatgcttat caagtcttgc aaacctattt cttgaataat
    27301 ccattcaaga ttatcgcaga gcgcgaggcc gtagtacagg cacaaaaaga tttggaaaat
    27361 agaaaaagaa aagccaagaa aaaggctcag aaaacgaaat aaataaggag gaatctggta
    27421 atggtagtat ttacaggttc aactgttgaa gaagcaatcc agaaaggatt gaaagaatta
    27481 gatattccaa gaatgaaggc tcatatcaaa gtcatttcta gggagaaaaa aggctttctt
    27541 ggtctatttg gtaaaaaacc agcccaagtg gatattgaag cgattagtga aacgactgtt
    27601 gtcaaagcaa atcaacaggt agtaaaaggc gttccgaaaa aaatcaatga tttgaacgag
    27661 cctgtgaaga cggttagtga agaaaccgtt gaccttggtc atgtagttga tgctattaaa
    27721 aaaatagagg aagaaggtca aggtatttct gatgaagtca aggctgaaat cttaaaacat
    27781 gaaagacatg ccagcactat cttagaagaa actggtcaca ttgagatttt aaatgaactt
    27841 caaatcgagg aagcgatgag ggaagaagca ggcgctgatg accttgaaac tgagcaagac
    27901 caagctgaaa gtcaagaact agaagacttg ggcttgaaag ttgaaacgaa ctttgatatt
    27961 gaacaagtag ctacggaagt aatggcttat gttcaaacga ttattgatga catggatgtt
    28021 gaggctacac tttcaaatga ttataaccgt cgtagcatca atttgcaaat tgatactaac
    28081 gaaccaggtc gtattatcgg ctaccatggt aaagtcttga aggccttgca actgttggct
    28141 caaaattatc tttacaactg ctattcaaga accttctata tcactattaa tgtcaatgat
    28201 tatgttgaac accgtgcaga agtcttgcag acctatgcgc aaaaattggc gattcgtgtt
    28261 ttagaagaag gacgtagtca tcaaacagat ccaatgtcga atagtgaacg caagattatc
    28321 caccgtatta tttcacgtat ggatggcgtg accagttact ctgaaggtga tgagccaaat
    28381 cgctatgtcg ttgtagatac agaataagta aaatcagggt tgacctgatt ttttgctagc
    28441 tagaggaggt taaactgatg ttgaataaga taagagacta tttagacttt gctggtttgc
    28501 agtaccgtaa tcctgataaa gcgggagcag agcgagagaa gatgctggca ttccgccaca
    28561 aaggacaaga ggcccgaaag gcttttacag aactggccaa agcctttcaa gcaagccatc
    28621 cagaatggca actccaacag actagtcagt ggatgaatca ggcccagcgt ttgagaccac
    28681 atttttgggt ttatctacag agagacggac aagtgacaga acctatgatg gccttacgtt
    28741 tgtatgggac atctactgac tttggaattt ctttggaagt cagtttcatc gaacgtaaga
    28801 aggatgagca aacactgggc aagcaggcca aagttttaga cattccaacc gttaaaggga
    28861 tttattatct aacctactct aatggtcaaa gtcaacggtg ggaggcgaat gaagaaaagc
    28921 gtcgtacttt acgcgagaag gtgagaagtc aagaagttcg aaaagtttta gtgaaggtag
    28981 atgttcctat gacagaaaat tcgtctgaag aagaaatcgt agaaggctta ttgaagtctt
    29041 attctaaaat tcttccctat tatctagcta cgagaaaata agataatttg taaaacatca
    29101 taaatcatac agtccaagag tgaacagtcc gctgtgtaat tcttggtctt tttgtttgcg
    29161 ctttcgcatt atataataaa cttacaaaaa caattcaaaa ggagaacaat tatggaagtc
    29221 gtttcaagtg ttctaaattg gttttctagc aatattttgc agaatcccgc atttttcgta
    29281 ggtttattgg tgttgatagg atatgcactt ttgaaaaaac ctgcccatga cgttttttca
    29341 gggtttgtta aagcaacagt agggtatatg ttgcttaacg tgggtgctgg tggtttggtt
    29401 acaacctttc gtccaatctt agcagctctt aactacaaat tccaaattgg tgcagcggtt
    29461 atcgaccctt actttggact tgctgcagca aacaacaaaa ttgcagcaga gtttccagat
    29521 tttgttggaa ctgcaactac agctctattg attggttttg gaataaatat cttgctcgta
    29581 gctcttcgaa agattacgaa ggtaagaacc ctctttatta ctggtcacat catggtacaa
    29641 caagctgcaa cagtatctct tatggttcta ttcttagtac cacaattgcg caatgcttac
    29701 ggtacagcag cgattggtat catctgtgga ctttactggg cagttagttc aaatatgact
    29761 gttgaggcaa ctcaacgctt gactggtggt ggcggatttg cgattggtca ccaacagcaa
    29821 tttgcaatct ggtttgtaga taaagtagca ggacgctttg gtaagaaaga agaaagttta
    29881 gacaatctta aattacctaa gttcctctca atcttccacg atacagttgt tgcatctgct
    29941 accttgatgc tcgtattctt cggagccatt cttttaatct tgggtccaga cattatgtct
    30001 aataaagaag tcatcacttc aggaactcta ttcaatcctg ctaaacaaga tttctttatg
    30061 tacattatcc aaacagcctt taccttctca gtttacttgt tcgttttgat gcaaggtgtc
    30121 cgaatgttcg tatctgagtt gacaaacgcc ttccaaggta tttcaaacaa attgttgcca
    30181 ggttcattcc cagcggttga cgttgcagct tcttatggat ttggttctcc aaatgctgtc
    30241 ttgtcaggat ttacctttgg tttgattggt caattgatta caattgtctt gctcatcgtc
    30301 tttaaaaatc cgattcttat tattacagga tttgtaccag tgttctttga caatgcagcc
    30361 attgcggtct acgctgataa acgcggcgga tggaaagcgg ctgttatcct ttcctttata
    30421 tcaggtgtcc ttcaagttgc tctaggagct ctttgtgtgg cccttctcga tttggcatct
    30481 tatggtggct accatggaaa tatcgacttt gaattcccat ggcttggatt tggatatatc
    30541 ttcaaatacc ttggtattgt tggttatgta cttgtgtgtc tcttcttgct tgttattcct
    30601 caacttcaat ttgccaaagc aaaagataaa gagaaatatt acaacggtga agttcaagaa
    30661 gaagcttagt atctagaaaa ggagaaataa aatggttaaa gtattagcag cgtgcggaaa
    30721 tggaatgggt tcatcaatgg ttatcaagat gaaggttgaa aatgctctcc gtaagcttaa
    30781 tcaaacagat tttacagtca attcatgcag tgtcggtgaa gctaaaggtt tagcagtagg
    30841 atatgacatc gtaatcgctt ctcttcattt gattcaagaa ttggaagggc gaactaatgg
    30901 gaagttaatt gggcttgata acttgatgga tgataaagaa atcaccgaaa aactcagtca
    30961 agcactacag taaaaggttg gagggggctg gacagaaact gagagttatc gtttctgtcc
    31021 ttctccctct ttaaataaag gaggcagata tgaatttaaa acaagcttta attgacaatg
    31081 actcgatccg actaggttta gaggctaaca attggaaaga agcagtcaag gtagcagtag
    31141 atcccttaat tgaaagtggg gcaattttgc cagagtatta cgatgctatc attgaatcga
    31201 ctgaagagta tgggccttac tatatcttga tgccaggtat ggctatgccc cacgctagac
    31261 ctgaagctgg tgtgcaaagt gatgcctttt cattgattac cttacaaaat cctgttgtat
    31321 tttcagatgg gaaagaggta tctgttttgt tggcactagc agcaacaagt tcaaaaattc
    31381 acacaagtgt agccattcca caaattattg ccctgtttga attagaagat tctattgcac
    31441 gtttacaggc ttgccagact aaagaagatg tcttggctat gattgaagaa tctaaggata
    31501 gcccttatct cgaaggattg gatttggaaa gttagaaaga ggaataaaga aatgacaaaa
    31561 agaataccta atttacaagt tgcattagac cattcagact tgcaaggagc gattaaagca
    31621 gctgtttctg ttggtcagga agtagatatt atcgaagctg gaactgtttg cttgcttcaa
    31681 gttggaagtg aactggctga agtcttgcgt agccttttcc cagataagat tattgtggca
    31741 gacacaaaat gtgctgatgc tggtggaaca gttgctaaaa ataatgcggt tcgtggagca
    31801 gactggatga cttgtatctg ttgtgcaacc atccctacta tggaagcagc tctaaaggct
    31861 atcaagactg aacgaggaga acgaggcgaa atccagatcg agctttatgg cgattggact
    31921 tttgaacaag ctcagctttg gctagatgca ggtatctcac aagctattta tcaccaatct
    31981 cgtgatgctc ttcttgctgg tgaaacttgg ggtgaaaaag accttaataa ggttaaaaaa
    32041 ctcattgata tgggcttccg tgtatctgta acaggtggtc tagatgtaga tactctcaaa
    32101 ctctttgaag gtgttgatat ctttaccttt atcgcaggtc gtggaattac agaggctgcg
    32161 gatccagcag gagcagcgcg tgccttcaag gatgaaatca aacgaatttg ggggtaaatc
    32221 atggtacgtc caattggaat ttatgaaaag gcaaccccaa cacactttac ttggctagaa
    32281 cgtttaaatt ttgccaagga gttaggcttt gattttatcg agatgtctat tgacgaacgt
    32341 gacgagcgtt tagcaagact tgactggagt aaggaagaac gcttggaagt tgtcaaagaa
    32401 atctatgaaa ctggtgttcg tattccttct atctgttttt caggccatcg tcgctaccca
    32461 ttgggatcaa aagattcagt tctagaggaa aaatctctag aactcatgaa aaaatgtatc
    32521 gaattagctc aagacttggg agttcgtacg attcaattag ctggttacga tgtttactat
    32581 gaggaaaagt caccccagac acgccaacgt tttatcaaaa atttgagaaa agcctgtgac
    32641 tgggctgaag aagctcaggt ggtacttgct attgaaatta tggatgatcc tttcatcagt
    32701 agcatcgaaa aatatttggc tatagaaaaa gagattgact ctcccttcct ctttgtatat
    32761 ccagatattg gtaatgtgtc tgcatggcat aatgatatct atagtgagtt ttatcttggt
    32821 catcatgcca tcgcagctct ccatctcaag gatacttatg cagtgacaga aagttcaaag
    32881 ggccagttcc gagatgtacc tttcgggcaa ggttgtgtca aatgggaaga agctttcgat
    32941 attttaaagg aaaccaatta taatggacct ttcctaatcg aaatgtggtc tgaaaattgt
    33001 gaaacagtag aagaaacacg cgcagccatt caagaggcgc aagcttttct ctatccactc
    33061 attaagaaag caggtttgat gtaagatgaa tcaagtaatc aatgctatgc gtaaacgagt
    33121 ctgtgatgcc aatcaatcat tgccaaaaca tggacttgtc aaatttacct gggggaatgt
    33181 atctgaagtc aatcgcgaac tcggtgtcat tgttatcaaa ccatcaggcg tggattatga
    33241 cgaattgaca cctgaaaaca tggtagtgac tgatctagat ggtaagatcc tagaagggga
    33301 tttaagacca tcttccgacc tcccaactca tgtgcaatta tataaggctt ggtcagaaat
    33361 tggtagtgtg gttcacaccc attcgacaga agctgttgct tgggctcagg caggtcgtga
    33421 tattcctttc tacggaacaa cccatgcaga ttatttctac ggttcaattc cttgcgcccg
    33481 tagtttgacc aaggacgaag tagaagtggc ctatgaaaaa gatactggcc tggttatcgt
    33541 agaagagttt gaacatcgcg gacttaaccc ggttgaagta ccaggaattg ttgtacgcaa
    33601 tcacggtcca ttcacctggg gcaaaaatcc agagaatgct gtttatcact ctgtcgtact
    33661 agaggaagta tcaaagatga atcgctttac agaacaaatc aatccaagag ttggacctgc
    33721 tccccagtac atactagaaa aacactacca acgtaaacat ggaccaaatg cttattatgg
    33781 tcaaaagtaa gaacgatgaa ggaggagaaa aagataaatt tagctcctct ttttacattt
    33841 gatttttatt gagagtaaag ttggagttga agtaatttta aaagattttt tagaaatagc
    33901 gcttgatata tatatggtaa aataaaaaga attgctgtga tatcaataga tttgggggat
    33961 tttttaatat ggtactggat aaggcaagtt gtgatttgct tcaatatttg atggatcaag
    34021 aaacgtccaa aacgattatg gcgatttcga aagatttgaa agagtcaaga aggaaaattt
    34081 attatcacat tgacaaaatc aatgctgctc tgggtgacga ggcgcttcac atcattagta
    34141 ttccacgaat tggtattcac ttaacggaag agcagagaga tgcttgttgt aaactattat
    34201 cggaagtaga ttcgtacgat tatatcatga gtgcgcatga acgtatgatg ataatgttac
    34261 tatggatagg tatttctaaa gaacgtatta cgattgaaaa attgatagag ttaacagagg
    34321 tatctaggaa tactgttctc aatgatttga atagtattcg ttatcaacta actttggaac
    34381 aatatcaggt gatcttgcaa gtgagcaagt cacagggata ccaccttcat gcccaccctc
    34441 ttaataaaat tcagtatctt caatcgcttc tatatcatat ttttatggaa gaaaatgcca
    34501 cttttgtatc tattttagaa gataagatga aagagaggtt agatgatgag tgtttgcttt
    34561 ctgttgaaat gaaccaattt tttaaggaac aggttccttt agttgaacaa gatttaggga
    34621 agaaaataaa tcatcatgaa ataactttta tgttgcaggt tctaccttat ttgctgttaa
    34681 gctgtcataa tgttgaacag tatcaagaaa gacatcagga tatagagaaa gaattttctt
    34741 tgataagaaa aagaatagag tatcaggtgt ctaagaaatt aggagaacgg ttgtttcaaa
    34801 agtttgaaat ttctttgtca ggacttgaag tttctcttgt agctgttctc ctcctctcct
    34861 atcgtaaaga tttggatatt catgcagaaa gtgatgattt tcggcaatta aaacttgctt
    34921 tagaagaatt tatctggtat tttgaatcac aaatccgaat ggagattgag aacaaggatg
    34981 atttgttacg aaatttgatg atccactgta aagccttgtt atttagaaag acttacggta
    35041 ttttttctaa aaatcctcta acaaaacaaa ttcgatccaa gtatggagaa ttatttttag
    35101 tcactagaaa atctgcggaa attttagaag gagcatggtt tattcggcta acagacgatg
    35161 atattgccta tttgacgatt catattggag gatttttaaa gtatacacca tcgtctcaaa
    35221 aaaatatgaa aaaagtttat ctcgtttgtg atgaaggtgt tgcggtttcg agacttttgc
    35281 tgaaacaatg caaactttat tttccaaatg agcaaattga cactgtattt acaacagaac
    35341 aatttaagag tgtggaagat attgcacaag ttgatgtagt gattactact aatgatgatt
    35401 tggatagcag atttccgatt ttaagggtta atcctatcct tgaagcagaa gatattttga
    35461 aaatgctaga ctatcttaaa cacaatatat ttcgtaataa gagcaaaagt ttcagtgaaa
    35521 atctttctag tcttatttcg tcttatattg tagacagcaa gttggctagt aagttccaag
    35581 aagaggttca aacacttata aatcaagaaa tagtagttca agcttttttg gaagatattt
    35641 gaaggacagt ccaatgatga acacaaacct gtgtttttct tggtcttttt tagtgttttg
    35701 aagggtggta tactaatctc aaagataaca attatatcca aaggaggcaa catatgccaa
    35761 acgtcaaaga aattacaaga gagtcatgga ttttagccac tttcccagag tggggaacat
    35821 ggttgaacga agaaatcgaa gaagaagtcg tacctgaagg caactttgcc atgtggtggc
    35881 taggcaactg tggtacttgg attaagacac cagctggtgc taacgttgtc atggaccttt
    35941 ggtcaaaccg tggaaaatca accaaaaaag tgaaagatat ggttcgtggg caccaaatgg
    36001 caaatatggc aggtgttcgt aaattgcaac caaacttgcg tgttcagcca atggttatcg
    36061 atccatttgc tatcaacgaa ctagactatt acttagtttc acacttccac agtgatcata
    36121 tcgacccata cacagctgca gcaattctca acaatcctaa gttagagcat gttaagttta
    36181 tcggtcctta ccactgtgga cgaatctggg aaggatgggg ggttccaaaa gaacgtatca
    36241 tcgttgttaa accaggtgac actatcgaat taaaagatat gaagattcat gcagtagaat
    36301 catttgaccg tacttgcttg gtaactctcc cagtgaacgg tgctgatgag acaggcggtg
    36361 aacttgctgg cttggctgtt acagatgaag aaatggctca aaaggctgtt aactatatct
    36421 ttgaaacacc aggtggaacc atctatcatg gtgcagattc tcacttctca aactattttg
    36481 caaaacatgg taaagacttt aaaattgatg ttgctttgaa taactatggt gaaaatccgg
    36541 taggtatcca agacaaaatg acatctatcg accttcttcg tatggcagaa aatctgcgta
    36601 ccaaagtcat tatcccagtt cactatgata tctggtctaa cttcatggct tctactaatg
    36661 agattctaga actttggaaa atgcgaaaag atcgcttgca atacgatttc catccattta
    36721 tctgggaagt tggcggtaag tacacttatc ctcaagatca acacttagta gaataccatc
    36781 atccacgtgg ttttgatgat tgttttgaac aagactctaa cattcaattt aaagctttgc
    36841 tataatataa aaatattctt tggaggttat ccgtatgttg catgatacgg ataattttca
    36901 tataatagta aaatagaatg tgtgattcaa taatcacctc aaatagaaag gaaattctat
    36961 gtcaaatcta tctgttaatg caattcgttt tctaggtatt gacgccatta ataaagccaa
    37021 ctcaggtcat ccaggtgtgg ttatgggagc ggctccgatg gcttacagcc tctttacaaa
    37081 acaacttcat atcaatccag ctcaaccaaa ctggattaac cgcgaccgct ttattctttc
    37141 agcaggtcat ggttcaatgc tcctttatgc tcttcttcac ctttctggtt ttgaagatgt
    37201 cagcatggat gagattaaga gtttccgtca atggggttca aaaacaccag gtcacccaga
    37261 atttggtcat acggcaggga ttgatgctac gacaggtcct ctagggcaag ggatttcaac
    37321 tgctactggt tttgcccaag cagaacgttt cttggcagcc aaatataacc gtgaaggcta
    37381 caatatcttt gaccactata cttacgttat ctgtggagac ggagacttga tggaaggtgt
    37441 ctcaagcgag gcagcttcat acgcaggttt gcaaaaactt gataagttgg ttgttcttta
    37501 tgattcaaat gatatcaact tggatggtga gacaaaggat tcctttacag aaagtgttcg
    37561 tgaccgttac aatgcctacg gttggcatac tgccttggtt gaaaatggaa cagacttgga
    37621 agccatccat gctgctatcg aaacagcaaa agcttcaggc aagccatctt tgattgaagt
    37681 gaagacggtt attggatacg gttctccaaa caaacaagga actaatgctg tacacggcgc
    37741 ccctcttgga gcagatgaaa ctgcatcaac tcgtcaagcc ctcggttggg actacgaacc
    37801 atttgaaatt ccagaacaag tatatgctga tttcaaagaa catgttgcag accgtggcgc
    37861 atcagcttat caagcttgga ctaaattagt tgcagattat aaagaagctc atccagaact
    37921 ggctgcagaa gtagaagcca tcatcgacgg acgtgatcca gtcgaagtga ctccagcaga
    37981 cttcccagct ttagaaaatg gtttttctca agcaactcgt aattcaagtc aagatgcctt
    38041 gaatgttgtg gcagctaaat taccaacctt cctaggtgga tcagctgacc ttgctcactc
    38101 aaacatgact tatatcaaga cggatggact tcaagacgat accaatcgct tgaatcgtaa
    38161 cattcagttt ggtgttcgtg aatttgcaat gggaacaatc ttgaacggga tggcccttca
    38221 tggtggactt cgtgtatacg gtggaacttt cttcgtcttc tctgactatg tgaaggcagc
    38281 tgtccgcttg tcagccttac aaggacttcc tgtgacttat gtctttaccc atgattcaat
    38341 cgcagttggg gaagatggtc cgactcacga accggttgag catttagcag gtcttcgtgc
    38401 tatgccaaat ctaaatgttt tccgtccagc agatgcgcgt gaaacgcaag cagcttggta
    38461 ccttgcagtg acaagtgaga aaacaccaac tgcccttgtc ttgacacgtc aaaacttgac
    38521 tgttgaagat ggaacagact tcgacaaggt tgctaaaggt gcttatgttg tatatgaaaa
    38581 tgcagccgac tttgatacca tcttgattgc gacaggttca gaggttaatc ttgctgtctc
    38641 agctgctaaa gaattggcta gtcaaggcga aaaaatccgc gtagtcagca tgccatctac
    38701 agatgtcttt gataaacaag atgcagctta caaggaagag attcttccaa atgcagtccg
    38761 ccgtcgtgtt gcagtcgaaa tgggtgcaag tcaaaactgg tacaaatatg ttggtctcga
    38821 tggtgccgtt ctaggtatta ataccttcgg agcctctgcc ccagcaccaa aagtattggc
    38881 agaatatggc tttactgtag aaaatcttgt aaaaattgtt cgaaacttga aataatccta
    38941 aaaatcaggg cgtaagctct ggtttttctt accagaaaag taaggtacaa tcttgtaaaa
    39001 gtagctgaaa tttgatatag tagtcctatg taaaagacaa aggagaaagc aatgaatcca
    39061 aatattactt ttttaatcat gcttgtaggt atgatggcct tgatgttctt tatgcaacgt
    39121 tctcaaaaga aacaagctca aaagcgtatg gaaagcttaa ataaactaca aaaaggctat
    39181 gaagtgatta caatcggtgg actttatgga acagtcgatg aagtagatac ggagaaggga
    39241 acaatagttc ttgacgtaga tggagtttac ttgacttttg aactagctgc tatcaagaca
    39301 gtattaccgc tgaaagaaac agcttcacta gaaggcgcaa ttgaaaaata agacgggatc
    39361 acgaactccc gtttttctat aaaagaaagg aaatgggatg aaaaaattag tctttgtctg
    39421 tctgggaaat atttgccgta gccctatggc cgagtttgtt atgaaatcaa tgacagataa
    39481 ctacgaaatc caaagtcgag caacttcctc ttgggaacat ggcaatccga ttcataaggg
    39541 gactcaggga atttttcaag agtatgagat tccttatgac aagaacaaga catcgcttca
    39601 gattagtaag gaagattttg aagcctttga ttatattatc ggaatggacg cttcaaatat
    39661 ttctgactta cgtcagatgt gtccagtaga ctgtcaagat aagatttact cattttcatc
    39721 tgaaagtgtt ccagaccctt ggtatacagg agattttgaa gaaacctatc gacgtgttca
    39781 agagggctgt caagcttggt tagaacgttt agaaaaggag agttaaggtg gaaaatctta
    39841 cgaattttta cgaaaagtat cgtgtctatc tgactcgtcc acgattagag cttttggcag
    39901 tagttaccat tgttttctgt gctgtactcg tcttttttct aaatattcca ggaaaaggtg
    39961 tcttaaaact cgataatgga acgattgttt atgatggcag tcttgtccgt ggtaaaatga
    40021 atggtcaagg taccattacc ttccaaaatg gagaccaata tacaggtggc ttcaacaatg
    40081 gagccttcaa cggaaaaggt acctttcaat ctaaagaagg ctggacctac gaaggtgatt
    40141 ttgtaaatgg tcaggctgaa ggaaaaggga aactaacaac agaacaagaa gtcgtttatg
    40201 aaggaacttt taaacaaggc gtttttcaac aaaaataaag cctccttatc aaaggaggta
    40261 ttattagaat cgcaaggtaa gcgcttacct gcaaatccct ttctttccaa atccctcttc
    40321 caaccaagtt tgtgaaataa aaaatatttg aaataaattt cacaaacttc aaagataaaa
    40381 cctgataaga aaagaaaatg agaaaagttt cacaagagtt taaaaattct ttgtgaaatg
    40441 tttatgaaac tgtttacaaa gttgaaataa tgcgttataa taaacttgtg aaaaaattaa
    40501 caaaggatat cgttccttga aagctatgga ggaaaatatg gctgataaaa aaactgtgac
    40561 accagaggaa aagaaactcg ttgctgaaaa acacgtagat gagttggttc aaaaagctct
    40621 agttgccctt gaagaaatgc gtaaattgga tcaagaacaa gttgactaca tcgttgccaa
    40681 agcatcagta gcagctttgg atgcccacgg agaattggct ttacatgcct ttgaagaaac
    40741 aggacgtggt gtatttgaag ataaagcaac taagaacttg tttgcttgtg aacacgtggt
    40801 aaacaacatg cgtcacacta aaacagttgg cgttatcgaa gaagatgatg taacaggatt
    40861 gaccctgatt gctgaaccag ttggtgttgt ttgtggtatc actccaacaa caaacccaac
    40921 atcaacagcg atcttcaaat cattgatttc attgaagaca cgtaatccaa tcgtctttgc
    40981 cttccatcca tcagctcaag aatcatcagt tcatgcagct cgtatcgtcc gcgatgcagc
    41041 tatcgcagct ggtgctcctg aaaactgtgt acagtggatc actgaaccat ctatggaagc
    41101 aactagtgcc cttatgaacc acgaaggtat tgcaacaatc cttgcaacag gtggtaatgc
    41161 catggttaaa gccgcatact catgtggtaa accagctctt ggggtaggtg ccggaaacgt
    41221 tccagcttat gttgaaaaat cagcaaacat tcgtcaagca gcacacgata tcgtcatgtc
    41281 taaatcattt gataacggta tggtctgtgc atctgaacaa gcagttatca ttgataaaga
    41341 aatttacgat gaatttgtag cagagttcaa atcttaccac acttactttg taaacaaaaa
    41401 agaaaaagct cttcttgaag agttctgctt cggcgtcaaa gcaaacagca aaaactgtgc
    41461 tggtgcaaaa ttgaacgctg acatcgttgg taaaccagca acttggattg cagaacaagc
    41521 aggatttaca gttccagaag gaacaaacat tcttgctgca gaatgtaaag aagttggcga
    41581 aaatgagcca ttgactcgtg aaaaattgtc accagttatt gcagttttga aatctgaaag
    41641 ccgtgaagat ggtattacta aggctcgtca aatggttgaa tttaacggtc ttggacactc
    41701 agcagctatc cacacagctg acgaagaatt gactaaagaa tttggtaaag ctgttaaagc
    41761 tattcgtgtt atctgtaact caccttctac ttttggtggt atcggggacg tttacaatgc
    41821 cttcttgcca tcattgacac ttggatgtgg ttcttacgga cgcaactcag ttggggataa
    41881 cgttagtgcc attaacctct tgaatatcaa aaaagtcgga agacggagaa ataacatgca
    41941 atggatgaaa cttccttcaa aaacatactt tgaacgtgat tcaattcaat accttcaaaa
    42001 atgtcgtgac gttgaacgtg tcatgatcgt tactgaccat gccatggtag agcttggttt
    42061 ccttgatcgt atcatcgaac aactggacct tcgtcgcaat aaggttgttt accaaatctt
    42121 tgcggatgta gaaccggatc cagatatcac aactgtaaac cgtggtactg agattatgcg
    42181 tgccttcaga ccagatacca tcatcgcact cggtggtggg tctccaatgg atgctgccaa
    42241 agtaatgtgg ctcttctacg agcaaccaga agtggacttc cgtgaccttg tccaaaaatt
    42301 catggatatc cgtaaacgtg ccttcaagtt cccattgctt ggtaagaaga ctaaattcat
    42361 cgcgattcca actacatctg gtacaggatc tgaagtaaca ccatttgccg ttatctctga
    42421 taaagcaaac aaccgtaaat acccaatcgc tgactactca ttgacaccaa ctgtggcaat
    42481 tgtagaccct gctttggtat tgacagttcc aggatttgtt gctgctgata ctggtatgga
    42541 cgtattgact cacgcgacag aagcatacgt atcacaaatg gctagtgact acactgatgg
    42601 tttagcactt caagctatta aattggtctt tgaaaatctc gaaagctcag ttaagaatgc
    42661 agacttccac tcacgtgaga aaatgcataa cgcttcaaca atcgctggta tggcctttgc
    42721 caatgccttc ctaggtattt ctcactcaat ggcccataag attggtgcgc aattccacac
    42781 aatacacggt cgtacaaatg ctatcttgct tccatacgtt atccgttaca acggtacacg
    42841 tccagctaag acagcaacat ggcctaagta caactactac cgtgcagatg aaaaatacca
    42901 agatatcgca cgcatgcttg gacttccagc ttctactcca gaagaagggg ttgaatctta
    42961 cgcaaaagct gtctacgaac tcggtgaacg tattgggatc caaatgaatt ttagagacca
    43021 aggaattgac gaaaaagaat ggaaagaaca ttctcgtgaa ttagccttcc tggcttatga
    43081 agaccaatgt tcaccagcta acccacgtct tccaatggta gaccatatgc aagaaatcat
    43141 cgaagatgca tactatggct acaaagaaag accaggacgc cgtaaataat tgtttatcag
    43201 tctagaagca agacaaaaac tcaatttgag ggaaagatcc agtaattttt ctatgataaa
    43261 aggcatccta tcaaggtttt tgaacacctg ataggatgcc tttttatgat attgaggcct
    43321 ttttgccctt tttgaaaaac tagaatagaa acaaaatata taatagattg aaactggaat
    43381 agtacacttc tgcttctaaa aaattgttag aa
//
LOCUS       DAVIME010000014        42614 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVIME010000014 DAVIME010000000
VERSION     DAVIME010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.014"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(385..777)
                     /gene="rpsI"
                     /locus_tag="VV588_000793"
     CDS             complement(385..777)
                     /gene="rpsI"
                     /locus_tag="VV588_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU7083165.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(797..1243)
                     /gene="rplM"
                     /locus_tag="VV588_000794"
     CDS             complement(797..1243)
                     /gene="rplM"
                     /locus_tag="VV588_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU7083166.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            1600..1917
                     /locus_tag="VV588_000795"
     CDS             1600..1917
                     /locus_tag="VV588_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU7083167.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(2067..2879)
                     /gene="folK"
                     /locus_tag="VV588_000796"
     CDS             complement(2067..2879)
                     /gene="folK"
                     /locus_tag="VV588_000796"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU7083168.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(2922..3476)
                     /gene="folE"
                     /locus_tag="VV588_000797"
     CDS             complement(2922..3476)
                     /gene="folE"
                     /locus_tag="VV588_000797"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU7083169.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(3457..4779)
                     /locus_tag="VV588_000798"
     CDS             complement(3457..4779)
                     /locus_tag="VV588_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU7083170.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(4781..5755)
                     /gene="folP"
                     /locus_tag="VV588_000799"
     CDS             complement(4781..5755)
                     /gene="folP"
                     /locus_tag="VV588_000799"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU7083171.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(5850..6557)
                     /locus_tag="VV588_000800"
     CDS             complement(5850..6557)
                     /locus_tag="VV588_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7083172.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(6610..8028)
                     /locus_tag="VV588_000801"
     CDS             complement(6610..8028)
                     /locus_tag="VV588_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU7083173.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            8218..9030
                     /locus_tag="VV588_000802"
     CDS             8218..9030
                     /locus_tag="VV588_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU7083174.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            9369..10388
                     /gene="adhP"
                     /locus_tag="VV588_000803"
     CDS             9369..10388
                     /gene="adhP"
                     /locus_tag="VV588_000803"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU7083175.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKGKTDGGAHSAVVTAVSKVAFNQAVDSVRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVAPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            10622..11611
                     /gene="manX"
                     /locus_tag="VV588_000804"
     CDS             10622..11611
                     /gene="manX"
                     /locus_tag="VV588_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU7083176.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            11639..12442
                     /locus_tag="VV588_000805"
     CDS             11639..12442
                     /locus_tag="VV588_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU7083177.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            12466..13377
                     /locus_tag="VV588_000806"
     CDS             12466..13377
                     /locus_tag="VV588_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU7083178.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(13433..14767)
                     /gene="pepC"
                     /locus_tag="VV588_000807"
     CDS             complement(13433..14767)
                     /gene="pepC"
                     /locus_tag="VV588_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU7083179.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(14984..15706)
                     /locus_tag="VV588_000808"
     CDS             complement(14984..15706)
                     /locus_tag="VV588_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU7083180.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DINTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     KPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(16019..16249)
                     /locus_tag="VV588_000809"
     CDS             complement(16019..16249)
                     /locus_tag="VV588_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU7083181.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            complement(16259..17500)
                     /locus_tag="VV588_000810"
     CDS             complement(16259..17500)
                     /locus_tag="VV588_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU7083182.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVIFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSLVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(17522..17674)
                     /locus_tag="VV588_000811"
     CDS             complement(17522..17674)
                     /locus_tag="VV588_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083183.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            complement(17695..17973)
                     /locus_tag="VV588_000812"
     CDS             complement(17695..17973)
                     /locus_tag="VV588_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU7083184.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(17966..18229)
                     /locus_tag="VV588_000813"
     CDS             complement(17966..18229)
                     /locus_tag="VV588_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU7083185.1"
                     /translation="MSKMSMSIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            complement(18331..22722)
                     /locus_tag="VV588_000814"
     CDS             complement(18331..22722)
                     /locus_tag="VV588_000814"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU7083186.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VDKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     GAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(22826..24907)
                     /gene="fusA"
                     /locus_tag="VV588_000815"
     CDS             complement(22826..24907)
                     /gene="fusA"
                     /locus_tag="VV588_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU7083187.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(25332..25802)
                     /gene="rpsG"
                     /locus_tag="VV588_000816"
     CDS             complement(25332..25802)
                     /gene="rpsG"
                     /locus_tag="VV588_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU7083188.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(25822..26235)
                     /gene="rpsL"
                     /locus_tag="VV588_000817"
     CDS             complement(25822..26235)
                     /gene="rpsL"
                     /locus_tag="VV588_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU7083189.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            26652..30449
                     /gene="spuA"
                     /locus_tag="VV588_000818"
     CDS             26652..30449
                     /gene="spuA"
                     /locus_tag="VV588_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU7083190.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDLAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            complement(30549..31598)
                     /locus_tag="VV588_000819"
     CDS             complement(30549..31598)
                     /locus_tag="VV588_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU7083191.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SDGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHIPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            31655..31792
                     /locus_tag="VV588_000820"
     CDS             31655..31792
                     /locus_tag="VV588_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083192.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTNEVSNHTYGKATLTWFEEI
                     F"
     gene            complement(31869..33677)
                     /gene="glmS"
                     /locus_tag="VV588_000821"
     CDS             complement(31869..33677)
                     /gene="glmS"
                     /locus_tag="VV588_000821"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU7083193.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYFEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(33870..35249)
                     /gene="bglA"
                     /locus_tag="VV588_000822"
     CDS             complement(33870..35249)
                     /gene="bglA"
                     /locus_tag="VV588_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU7083194.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHCPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            complement(35349..37202)
                     /locus_tag="VV588_000823"
     CDS             complement(35349..37202)
                     /locus_tag="VV588_000823"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU7083195.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(37215..38474)
                     /gene="rseP"
                     /locus_tag="VV588_000824"
     CDS             complement(37215..38474)
                     /gene="rseP"
                     /locus_tag="VV588_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU7083196.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTVLPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGGKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(38496..39299)
                     /locus_tag="VV588_000825"
     CDS             complement(38496..39299)
                     /locus_tag="VV588_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU7083197.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(39308..40066)
                     /locus_tag="VV588_000826"
     CDS             complement(39308..40066)
                     /locus_tag="VV588_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU7083198.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(40297..40761)
                     /locus_tag="VV588_000827"
     CDS             complement(40297..40761)
                     /locus_tag="VV588_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU7083199.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(40850..41821)
                     /gene="ruvB"
                     /locus_tag="VV588_000828"
     CDS             complement(40850..41821)
                     /gene="ruvB"
                     /locus_tag="VV588_000828"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU7083200.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            41982..42074
                     /locus_tag="VV588_000829"
     CDS             41982..42074
                     /locus_tag="VV588_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU7083201.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
BASE COUNT        12387 a         9853 c         8249 g        12125 t
ORIGIN      
        1 cttccccatt ctatggaatc ttgcattatc cataatatag tagattgaaa ctagaatagt
       61 acacctctac ttctaaaaca ttgttagaat tcgatttgac tatcctcgat ttgtcctatt
      121 cttatttcat attactataa aaataaggta aacttttcaa aaaagcacga aaaaagcacc
      181 cataaggtaa acttttgagt gctttgaaac attgatataa tcgtattgat taacgttttg
      241 aggcaactga ccttgtcagg ttgcagccac atttgtaagc gactaaagtc gcaacaactg
      301 tgtcaattgc accaatttag taagaaagta taaaaaaaga acaccccgaa aggtgctctg
      361 tataagtata gtaattcttt cgaattaacg tttactaaat tgtgatgctt tacgagcttt
      421 cttaagacct ggtttcttac gttcaacttt acgtgagtca cgtgtaagaa gtcctgcgcg
      481 tttcaatgaa tcgcggaagt ctgggtctac ttgaagaagg gcacgagcga taccgtgacg
      541 gatagctcct gattgaccag cgtatccacc acctacaacg ttaacgaaaa cgtcgtatga
      601 acctacagtt gaagtaactg cgaatggttg gttgatgaca agacgaaggt cagcgtgtgg
      661 gatgtactct tcaacatctt ttttgttaac agtgatttta ccagttcctg gaacaaggcg
      721 aacgcgtgca acagcgtttt tacgacgtcc agtacctgca tattgtgctt gtgacatact
      781 ttatttgttc ctttccttag ataagtcctg aaatgtcaag aacttctggt tgttgtgcag
      841 catgagtgtg ctcagctcca acaaatactt tcaacttcat accttgagcg cgtccaagtg
      901 tattgtgtgg aagcatacct ttaactgatt tctcaatcaa acgtactgca tttttagaac
      961 gaagttcacc tgcagagatt tgtttcaatc cacctgggtg gtttgagtga gtgtagtaga
     1021 ttttatcagt tgctttttta ccagtcaatt taactttttc agcattgata acaatcacga
     1081 agtcacctgt atcagtgtgt ggtgtaaatg ttggtttgtt ttttccgcga agtacgctag
     1141 caactactgc agaaagacgt ccaagtggta catcagttgc gtcaactacg taccatttac
     1201 gttcaacttg gcctggttta gccataaatg ttgttttgtt catgatttct cctatatata
     1261 gttcgatttt tgtttacggt gatgggtgtt ccttcccatc gaaaagtatt tggaaggttc
     1321 cggggccttt caaatggggt aaacaatacc gcctactatc ataccaaatt tcacccctaa
     1381 aagtcaatag atatgaaaaa tatttttcgg taacttctca aagtaactga aagttatata
     1441 atcaagttaa tttgggaatt tacctattaa cttcggtaga tttttgggaa tttttttcct
     1501 tctttttccc tgtagttaaa atccttttca aaaaatcacc ttttcttgat ttttaatcct
     1561 atttgctgta tgataaggga aaagaaagga gacagagata tggcttttac caatacccac
     1621 atgcggtctg ctagttttgg cattgttacc agcttgcctg atgacatcat tgactctttt
     1681 tggtatatta tcgaccattt cttaaaaaat gtctttgaat tggaagaaga actcgagttt
     1741 caattgctta ataaccaagg aaagattacc ttccactttt caagtcaaca cctccctaca
     1801 gccattgatt ttgactttaa ccatcctttc gaccctcgtt atcccccaag agtactggtt
     1861 ttagacatgg acggtagaga aactatcctc ctcccagaag aaaatgacct attttaatac
     1921 tcaatgaaaa tcaaagagca aactaggaag ctagccgcaa gctgtacttg agtacggtaa
     1981 ggcgacgctg acgtggtttg aagagatttt cgaagagtat aaaaactcta gccttcagtt
     2041 gcaagtgact gaaaactaga gtttttctat tttttcaaag catcatacaa gttgcggatc
     2101 ggttgtttta atatcggatg gataaaatga ggcgcaattt cctgtaagga ctcaaggaca
     2161 aaaaggcgtt ccgctatata aggatgaggc aatatgaggt cgtctgtata aaggatctgg
     2221 tcctccacaa agagcaagtc caaatcaatc aaacgaggtc cccaatgcac ttctctcacc
     2281 cgtcccagct ctgactcaat ggctaacaag gtttctaaca agtcttgtgc tggtagccag
     2341 gtttccacct caaccacttg attggcaaag ctatcctgct ccactccacc ccaaggctcc
     2401 gtcgctaaga cactggactc tttgagaata tggatgccac gagctcgcag tttgtcaatg
     2461 gcttgcttca agtttgcttg cttatctccc atattgcttc ctagggcgat aaaggctcgt
     2521 tgcttgcggc gatgaatggt taccgagcaa gtatctagtg acaaatgcac cggtgcccaa
     2581 ggttttttca gttccaactt catttcttgg acaagaggat aagactcaaa ggtacgttcc
     2641 accagtttat aggctaccgt ttcaatcaaa tcttcactcg tttcctgaaa ccaagtcgtc
     2701 cactgctgac acaattctcc gtaatggaca gaggctgtta aatccaagtc tgtagctgcc
     2761 ttggtcatat cataggatag gatggctgaa acgacaaatt tctgccccaa ttctttctca
     2821 ctaggaaaaa gaccatgata ggcaaacatt tccaaatcct taatctgcag ttgatccata
     2881 atgattcctt tctagaaaaa tccgcttgaa acggattctt tttatagccc cattaaacga
     2941 taagcttggt cgcggaggtc cttatctgtt tcaaatagac cacgagctac tgtcgtcaag
     3001 gttgcagtgc ctggttttct aacaccacgc atactcatac acatatgttc cgcctcaatg
     3061 ataacaaagg ctcctttagc acctagatag tccatcaagg catcggccac ttcgatattc
     3121 aaacgttctt gaatttgtgg ttttttcgaa taaacttcaa ccgtacgggc tagcttagac
     3181 aagcctgcca cacgaccatc tggaatgtag gcaatgtgcg ctctaccata aaatggcaag
     3241 aagtggtgtt cacacatggt atggaaaaag atatcctttt ctaccaccat attatcgtca
     3301 ataatttcaa aggattttga caaatgttcc tctgctgttt gaccaagacc tgaaaaaatc
     3361 tcttgataca tacgggctac acgagcaggt gtttcctgca aaccctcgcg attagcgtcc
     3421 tctcctacag cctcgataat catttttaca gctgcttcaa tcttttgtgt atccattctc
     3481 gttcttcctc tccatcagat aggccctcac ttggctcaag aaatacaagg aacctgtgac
     3541 aatcctaact gtttgtttct cttctttttt atctgtcaaa ttctgctcta gaaaatcatg
     3601 ccaatcttgg tagctgagat ttctagactt agctgcctct ttcagcacgc tttcatccgt
     3661 cgcccgacta tccgcaaaat gtgttagagt aagctcggta tctggcatgg ctcccagcaa
     3721 gtccaacata tcctccaagg ccttggtttt gatacaagtg aagaggattt ccttatgata
     3781 atccgcaaaa cgttcttgca aggttaccaa caaggccttg atagcatggg gattgtgggc
     3841 tccatccaaa atcatcaagg gatctcttga cacgatttcc aaacgccctg gccaacttgt
     3901 ttcttccaag gcttgaccaa gaaagtcatt gcttgctagc tctcgaccat cttcttgaca
     3961 aaaagtatca agtaaagcta tggccatccc agcattctct atttggtaca aaccaagcag
     4021 gctagtctgg aagcgacctt gtctgacagc acttgtatag tcaaagactt cccctgtcac
     4081 cacactttct tgatgacgaa cctgataatc tgtcccgtag gcaagtctcg gcgaatcttt
     4141 cccttccgca atgcggtcaa tcacagtcaa ggcttctgga gcaatacgcc ctgttaccaa
     4201 gggcatccct tgtttgataa tacctgcctt ctgctctgct atggcctcca aggtgtcacc
     4261 aagtagggcc acatgatcca agccaatagt tgtaattcct gtcaaaatgg gctgacagac
     4321 attggtacta tccaaaagtc cacccatgcc aacttccatg atggccacat ctacttgctc
     4381 tgaggcaaag tagtcatagg ccagggctgt gataatctca aactcggttg tgccctgtaa
     4441 attggcgacc gcttctccct ccagcaaaga ctgatagtct gccatgagag cttctagcct
     4501 cgcttctgag atcgattccc cattgatgct aatctggtct gtgtaatgaa tgagataggg
     4561 cgagctaaac acgccaactc tcagccctag cttttctagc atctttttca aaaaagcaat
     4621 agtcgagccc ttgccgttag tccctccgat atggaggacc ttgagtttga gatggggatt
     4681 gccacgcaaa gctaacagtt ccaccattcg ttccaagcca aaatgcggtt gatccgtccg
     4741 gtagttagca atccactgat tgttttcaat ttctttcatc ttatttatat tgctttaaat
     4801 ctaaattttc cgcttcatca gccagacgaa tggcagatgc aatttcaact gccatcctgt
     4861 gactagctac gtcatgcacg cgcaccactt ctacaccctg tctcgcagcg atactagtta
     4921 catgagccga agccgtgtcc cgatttcgga aaccaagctc tgtctcagga ttgacttcaa
     4981 acccactttc ttcaaggata ttgatgacaa atcgcttgcg cgacactccg agaaagattg
     5041 gatagccctt ctgatgtagt ttatccagat cccgtaaaag gaggagattt tctttcttgg
     5101 tcagaccaaa gccaattcct ggatccaaca ggatattttc tggtgcaata ccagcttctg
     5161 ccgctctcgc tagtgctcgt tcaaagaaag ccaccatcaa gtcttcgatt ggcaatgttt
     5221 caaagtcagc taactcttct actgtaaaag tttgattaaa tccaaaatga gggaatatga
     5281 gcgagctagg gtgttgaggt cgcgccataa ctggattaaa catgatgacc acttgcgctc
     5341 tcgcttcagc taccacatga gccatttttt catcgcccat gagaccagtg atatcattaa
     5401 ctagattggc accagcagcc aaagcagcct ctgctacttg actcttccaa gtatcaatag
     5461 agatgaggac atcactttcc ttgcgaatcg ctttgatcac tggaacaaca cgctggattt
     5521 cctcttctat ctcaacatag ctactgcccg gccgagtcga ttctccgccg atatcgagca
     5581 tactggctcc ttctgctatc aatttacgag cctgctggag tgcctgctca agagcaaaaa
     5641 attgaccacc gtccgaaaag gagtctgggg ttacattgat aattccgcaa ataactgtct
     5701 ttgcatgatt ggctttactt gacatatcgg tcactccctc aaggattttc atcatattat
     5761 ttttctattt taccataaaa agaaaaagat ggacacgatt gcattcatct ttccctagta
     5821 gaaagaggtc ggtttctaca taaaagcttt taaacagaaa ttcctaatgt ccgactcata
     5881 atcaccacaa gagccaacaa acagaaagca atcccattaa caatcatgtg aagcaagatc
     5941 gacatttcca aacgttgggt cttgtaggcc gtccaagata gaactgtcga catacctcca
     6001 taaatcaata aagaaggtaa attacttggt tgatgcaata aagcaaacac aatcgtaccg
     6061 actacaaatc ccaagttctc cttgcctcgg aaaatctttt taggaacaat cccacggcac
     6121 aagatttcct cacaaatcgg agcaagcaag gctagcaaga agaaactgga aatcaacgaa
     6181 ctattttgaa ccatatcgtt aatctgagac tggttagctg ttgtcgtctc atttgacagt
     6241 tgcaacaaga tagaaccaag tatatttgac ccgacaataa ctaaataact caagcccaaa
     6301 cgtgccaaat ctttagctct aaaaaaagaa aaattaaaac tagctaactt ggttttacga
     6361 gctcccataa taaatagagc cagaaccaca attgaaaggc cagcaactat cagccctgac
     6421 tgtagcaggg ctacttcttt taaagtcaaa atagaggtaa ccactagggg aacctgatat
     6481 aaaaggacgg caagtaaaaa gaccaaaatc cagcctgcac gattcaacaa ttctttccac
     6541 atatttttct ctttcatcac ctatctcctt tgtattaaaa aaggggggaa atccccctgg
     6601 gtcattctat tataaggcca tgctgatgta gttaaggata aacaaggcat ccaaaatcca
     6661 aatcatggca tgaacatctt taacttgacc tttgacaagc ttagtcaaag tgtaagtcaa
     6721 gaaaccaact gcaatccctt gagtgataga gtagctgaat cccataaaga tagatgtgaa
     6781 gaaggcagga actgcttcag acatatcatc ccaatggata tttttcaagc taccaagcat
     6841 cataatccca acgataatca agattggagc tgtagccgct gttggtacga tcgctagaag
     6901 tgggctaaag aagcttgaaa tcgcaaaaca gatagctaca accaaggctg tcaaaccagt
     6961 acgtccacct gcaccgatac cagcagcaga ctcaacataa gtcgttacgt ttgaagtacc
     7021 tgcaatggca ccgactgtcg ttccaatcaa atcagagtaa agagccttat ccaatttggc
     7081 tgattggtga ttttcaccat ttgtcgctac aataccaact ttttcacctg taccgatcaa
     7141 ggtaccaatt gtgtcaaaaa tatctgtcaa tgagaaggca agaatggcca tcagagtttc
     7201 aggcaagcga gctgtatctg aaaccaaagc tcccaaacct tctgaaccaa gagctgcacc
     7261 aaagattgtc ttcaaatctt caaaagctgc accaacatgg ttattagcaa aatcgatact
     7321 agacaaatca accaaaccaa ctgcaatagc aagaacagtt gttgtcaaga tagagagaat
     7381 aattccccct ttaatccctt tgatgacaaa gaagatagta atggcaagtc ctgcaagagc
     7441 cactaaaaca gctggattat taaagctgac caatcctgga actgctgaag agtttgctgc
     7501 aatcgttgct tgagctttgt cagccccttc tcctacaaca gtatagttgc ctggatcaat
     7561 cgtgaatttc aaaagtccag cattcttaat ccctacatag gcaaggaaga caccgatacc
     7621 agctgaaata gctgagcgaa gagcattggg aatcgattca atgatcattt tacgaacatt
     7681 tgtcaaggta ataatcaatg aaataatccc acagatgaag accatagcta gggcttcttg
     7741 ccaagaataa ccaagcccga atacaactgt aaaggtaaag aaggcattga gtcccatacc
     7801 tggcgcttgg gcataaggta agttagcata aaaagccatc atcaaggtac ccgctactgc
     7861 accaataatc gtcgctagga agacgccctg agcaggcatt cctgtttgtg aaagtatttg
     7921 tgggtttaca aagagaatat agctcattgc aaagaaagtt gttaaaccag cgagaacctc
     7981 tgtacgaacg tctgtaccgt tctcttttag tttaaataat ttgtccatca tcaatctcct
     8041 tttaattttt acgaacaata atagaattat atcatttatc attcactttt tcaatgtatt
     8101 tgtttgattt gtttaagaaa ttaatccaat ttcatttttt gtttggaatc tgcttttctg
     8161 cctgctttct gttataatag aagacatctt atctgaaaac acactagaaa ggtccatatg
     8221 acgaaaaaaa ttattgcagt tgacctggat ggaaccctgc tcaactcaga cagtcaaatt
     8281 tctgacttta ccaaaagaac catcaaaaaa gttgctgaaa aaggccatca ggttattatt
     8341 acgacaggtc gcccttaccg tatgtcaaaa gatttttacc gtgaactggg cttagacact
     8401 cctatgatta acttcaacgg atcccttact catttaccag accaagtttg ggattttgaa
     8461 aagtgtttga ctgtagacaa aaaatatctg ctagatatgg ttcaacgttc agaggacatt
     8521 caagccgatt ttatcgctgg agaatatcgt aaaaaattct acattacaaa tcccaatgaa
     8581 gaaattgcca atcccaaact atttggtgta gaagctttcc agcctgaaga tcaattccag
     8641 cctgaattgg tgaccaagga ccctaactgt atcctcttgc agaccagagc cagtgacaaa
     8701 tatgccttgg caaaagaaat gaacgccttc taccagcatc aactttctat caatacctgg
     8761 ggaggtccgc tcaatatcct tgaatgtacc ccaaaaggtg tcaacaaggc ctttgctttg
     8821 gactacttgc tcaagataat gaatcgtgac aaaaaagatt tgattgcctt tggagatgaa
     8881 cacaatgata ccgaaatgct cgcttttgct gggaagggtt atgccatgaa aaatgccaat
     8941 ccagagctac tcccttatgc agatgagcaa atttccctta ccaacgacca agatggggtt
     9001 gccaaaaccc tacaagactt attcttataa cctatactga tactcaatga gaatcaaaga
     9061 gcaaactagg aagctagccg taggttgctc aaagcactgc tttgaggttg tagatgaagc
     9121 tgacgtggtt tgaagagatt ttcgaagagt atgaccagct tgcaagctgg tctttgtgct
     9181 cttttcacag tctcatcaac cagttaatcg attgttctac tttttgtctc caaaaccttg
     9241 gaaaaggctt tcttttgtga tatacttcac atataaatac aagagagctc gtcacactcg
     9301 actctgttga caaaaaatca atccagtccc gttgtccctg ttctcggtca atatcaagga
     9361 ggatagctat gaaagctgtt gttgtaaatc cagaaagcac tggtgttgct attgaagaaa
     9421 aagtactccg tccacttgaa actggggaag cacttgtaga agttgaatac tgtggtgttt
     9481 gccacaccga cctccacgtt gctcatggtg actttggtca agtcccagga cgtgttcttg
     9541 ggcacgaagg tatcggtatc gttaaagaga ttgctccaga tgtgaaaagc cttaaagtcg
     9601 gtgaccgcgt cagcgttgct tggttctttg aaggatgtgg cacttgcgaa tactgtacaa
     9661 ctggtcgcga aaccctttgc cgtacagtga aaaatgctgg ctactcagta gacggtggta
     9721 tggctgaaca atgtatcgta actgctgact atgctgtcaa ggttcctgac ggacttgatc
     9781 cagcccaagc ttcttctatc acatgtgctg gagtaacaac ctataaagct atcaaagaag
     9841 caaaagttga accaggccaa tgggttgttc tttacggtgc tggtggactt ggtaacctcg
     9901 ctgttcaata cgctaaaaaa gtattcaatg ctcatgttat cgcagtcgat atcaacaatg
     9961 acaaacttgc ccttgcaaaa gaagtaggcg ctgacattgt gattaacggc ctcgaagttg
    10021 aagatgtagc tggactcatt aaaggaaaaa ctgatggagg agctcattca gctgtcgtaa
    10081 ctgctgtgtc taaagttgcc ttcaaccagg ctgttgactc cgttcgtgct ggtggtcgcg
    10141 tcgtcgctgt tggtcttcct tctgaaatga tggaactcag tatcgttaaa acagtcctcg
    10201 atggaatcca agtcatcggt tctcttgtcg gaactcgtaa agacttagaa gaagccttcc
    10261 aatttggtgc agaaggtctg gtagccccag ttgttcaaaa acgtccagta gaagatgctg
    10321 ttgccatttt cgacgaaatg gaaaaaggtc aaatccaagg acgtatggta ctcgacttca
    10381 cccactaatc taatagaaac ctattttaaa agttggaagc ttcttctaac ttttttatat
    10441 taaattttta aataagaatt caagattact ccttaaaaac tcaacatatc aacatataaa
    10501 aataaaaatt ttttaatttt ttatgataaa tagttgcttt ttttatgaaa acggtttata
    10561 cttaaacagt cttaaagttt tcttaaatga aaactaaaac aaaaaaggag gaatgacaat
    10621 aatgagtatc ggaatcatta ttgcgagcca cggcgaattt gctgcgggta ttcatcagtc
    10681 aggatctatg atctttggtg aacaagaaaa ggttcaagtt gtgaccttta tgccaaatga
    10741 aggtcctgat gatctatacg ctaagtttaa taacgctgtt gctgcatttg acgcagaaga
    10801 tgaggttcta gttttggctg acctttggag tggttctcca tttaaccaag ctagtcgcgt
    10861 gatgggagaa aatcctgagc gtaagtttgc catcatcaca ggacttaact taccgatgtt
    10921 gattcaagcc tacacagagc gcctcatgga cgctgctgca ggtgtagaaa aagtcgctgc
    10981 taatatcatt aaagaagcca aggatggcat caaagctctt ccagaagagc taaatccagt
    11041 tgaagaagtt gcaagcgctg cagctgctcc agttgcccaa gctgctatcc cagaaggaac
    11101 tgttatcgga gacggtaaat tgaaaatcaa tcttgcccgt cttgacacac gtctacttca
    11161 cggtcaggtt gcaactgctt ggactccaga ttcaaaagca aatcgtatca tcgttgcttc
    11221 agataacgtg gctaaagacg accttcgtaa agaattgatt aaacaagcag ctccaggtaa
    11281 tgtcaaggct aacgtggttc caattcaaaa actgattgag atttcaaaag acccacgttt
    11341 tggagaaaca catgccctta tcttgtttga aacacctcaa gatgcccttc gtgccatcga
    11401 aggcggcgtg ccaatcaaga ctcttaacgt tggttctatg gctcactcaa caggtaaaac
    11461 attggtcaat accgttttgt ctatggacaa agaagatgtt gcgacatttg aaaaaatgcg
    11521 tgacttgggt gttgaatttg atgtccgtaa agtaccaaat gattctaaaa aagatttgtt
    11581 tgacttgatt aacaaagcca atgtcaaata agccattatt tatgaaagga ttttaaacat
    11641 gtctattatt tctatggttt tagtagtcgt tgtagccttc tttgcaggtc ttgaaggcat
    11701 cctcgaccag ttccaatttc accaaccact tgtagcctgt acccttattg ggcttgtaac
    11761 aggtcacttg gaagcaggga ttatcctcgg tggatcgctt caaatgattg cccttggttg
    11821 gtcaaatatc ggtgctgcta tcgctcctga tgctgcactt gcttctgtcg ctgctgccat
    11881 tatcatggtt cttggtggtg actttaccaa gactggtatc ggtgttgccc aagcggttgc
    11941 tatccctctt gccgtagctg gacttttctt gacaatgatt gttcgtacaa tttcagttgg
    12001 tttggttcat actgcagatg ctgccgctaa aaaaggtgac ttcggcgctg tggagcgtgc
    12061 gcatttcatt gcgctactct tccaaggact tcgtatcgcg cttcctgcag ctcttctcct
    12121 tatggtacca actgaaactg tacaaagtat ccttagtgcc atgccagact ggctcaaaga
    12181 tggtatggct atcggtggtg gtatggtcgt tgccgttggt tacgccatgg ttatcaacat
    12241 gatggcaact cgtgaagtat ggccattctt cgctcttggt ttcgttctcg ctgctgtgtc
    12301 agatattact ctaatcggat tcggtgctat cggtgttgct atcgctctta tctaccttca
    12361 cctttctaaa actggtggaa atggtggcgg aggagccgca acttctaacg acccaatcgg
    12421 cgatatccta gaagactact aagataagaa aggactgaaa acatcatgac tgaaaaactt
    12481 caattaacta aatcagatcg taaaaaagtt tggtggcgtt caaccttctt acaagggtct
    12541 tggaactttg aacggatgca aaacttgggc tgggcttata cactcattcc agctatcaaa
    12601 aaactctata ctaaaaaaga agatcaaatc gctgctcttg agcgtcacct tgagttcttc
    12661 aacactcatc catacgtagc tgctccagtc atgggggtta ctcttgcgct tgaagaagaa
    12721 cgtgctaacg gtgtggaaat cgatgacgct gctatccaag gggtcaaaat cggtatgatg
    12781 ggacctcttg ctggtatcgg tgacccagta ttctggttta cagtacgccc aatccttgga
    12841 tctctcggtg cttcacttgc ccttactggc aatatcttgg gtccactcct cttctttgtt
    12901 gcatggaact tgattcgtat gtcattcttg tggtatgttc aagagattgg atacaaggct
    12961 ggatcagaaa tcactaaaga tatgtctggt ggtatccttc aagatatcac taaaggagct
    13021 tctatccttg ggatgttcat tcttgctgtc cttgttcaac gctgggtaaa tattaaattt
    13081 gctttcgatg tttctaaagt tcaactagat gaaaaggctt atatccattg ggataaattg
    13141 ccagaagggt ctaaaggtat ccaagaagca ttcgcacaag taggacaagg attgtctcaa
    13201 actcctgaaa aagttactac tttccaacaa aacttggata tgttgattcc tggattatca
    13261 ggactactcc ttactttact ttgcatgtac ttacttaaga aaaaagtatc tccaatcact
    13321 attatccttg ccctcttcgc agtgggtatt gtggcacatg ttcttcacat catgtaatca
    13381 agcaactaaa aaggaaccag gttctaaaat ctgattcctt ttttctatgc ttttattcag
    13441 ccaaggctcc cattggatcc catggtgcaa gtacaattgg ttctgctcca taggcagctt
    13501 gttcttctgc tgtcagcaat tccttacgaa caacgatttg gtatgtgtat tcgtccatcc
    13561 aagcgtctga ggcaacaaag taaccatctg taccgacctt gtctccccat gagttttcaa
    13621 ccttccactt ggttgattta ccattttcgt ccaagtcaac acctgtcaag accatggcgt
    13681 gggtcatcaa gctttcgcta tagtccaaac gtccagcctt gtcttgagta agtttaatgt
    13741 ccatgcttga ttcaaagtca taaacatctg tcgcaaggat gccagcctta cggttactga
    13801 gctggccgac atcagaacca aaccaaacag tctcacctgc ttgcatttgg gcaatcgcca
    13861 attctttcaa gcgctccatt ggaacgttga tgtaacgaac tgcacggcta ccaaccacat
    13921 tccccaacat ctcaactgtg taagattttc cgtaaggttt atcagcagtt ggagcattga
    13981 taacagaaac gtagtcttct aaaggaagat tgacatattt cttgtaaaac tcttgtggtg
    14041 tgattccttt ttcacttttg tagttgttat ctttatcgcg ataagcaaag tcaaacttgc
    14101 gtggtggaag tcctaatgac atagcaagaa agttaaagat ttcttgcaag aggtcttctt
    14161 tcttagcttg aacagtcgct tgatctgcac cagaaacaag caagtcacgc aagatttgag
    14221 catcttgacg aagcaattta ttaaggatcg catttagctc acgactgctg ctagatgaaa
    14281 cagactcagg ataaactgac ttaggcacga caccgtattt ttcaaagagg gaaacgacca
    14341 tatcccattg accaccatct tgttgaggtg tttggagtaa gaagctaacc ttgcggctag
    14401 tcaattcttg gtctgaagtc gcaatgactt gctccaagaa ccagtttgat ttctcatact
    14461 tatcccagaa gaaagtgtgg gcttgtgaca actcaaagtt ctccaatttg tattgcgaga
    14521 tgagtttgtg gcggaaggtg ttgagagccg caaacatcca gcaacgacca gacgctttct
    14581 ggttagtgac cttgtccttg gttaaatcca atgagaaaac aggtgtgttg tctacatggc
    14641 tttggcgacg ttccagagct gcaaaaattc cgttgtggct agcagcattt tcaatcgctt
    14701 ggtattttac atttgcttca tagttggcaa atagtttatc agtaaatgat tcttgaatcg
    14761 cgttcataga ttcctccttt tattctacag tctattataa ctcttttcac aaaggaagca
    14821 actaaaaaac ataaaaggta aggacattct ccctcacctt tttcgaatat atactcttcg
    14881 aaaatctctt caaaccacgt caacgtcgcc ttgccgtact caagtacagc ctgcggctag
    14941 tttcctagtt tgctctttga ttttcattga gtattaaact aaattaaata atattagcgc
    15001 ggagaatttc taattcttcc ttggtcaagc gacgccattc ccctcgttcc aggttctcat
    15061 ctaatactaa agttcccata gtcaatcgtt gcaagtccac cacttccttg ccacagtagc
    15121 ccaccatacg cttgatctga tgaaacttcc cttctgcaat ggtcacacgg atttggcttt
    15181 gattcttttc tgtatctatg gatacaagct ccagtatagc gggtttacag gtaaagtctt
    15241 tgagaggaat accctcagca aatgtctcca catcttcttg ggtcatgatt cccttgactt
    15301 gtgccagata agtcttgtcc acatgacgct tgggcgaaag aagaacatga gccagctgac
    15361 catcattggt caagagcaaa agaccatgcg tgttaatatc caagcgtcct actgggaaaa
    15421 cttccttact ccgcgccaag tcatccaaca agtccagaac ggttctgtgc ttgggatcct
    15481 cagtcgctga gataactcct ttgggcttgt tcatcatgta gtagacaaac tcttcatact
    15541 ccaacacttg cccatcaaag cgaatctcat ctattttttc atcaatctgc aatttagctg
    15601 atttttcttt tttaccattt acagtcacgc gcccagcctt gagcaagttt ttgacctcag
    15661 tccgacttcc caccgcacag gcaactaaaa atttatctaa tctcatagaa ctattatatc
    15721 atatcaaaag gaggctggta caatgaccaa cctccttttc gtttcatact cttcaaaaat
    15781 ctcttcaaac cgcgtcaacg tcgccttgcc gtatatatgt tactgacttc gtcagttcta
    15841 tctgcaacct caaaacagtg tttttagctg acttcgtcag ttctatctgc aacctcaaaa
    15901 cagtgttttt agctgacttc gtcagttcta tctgcaacct caaagcagtg ctttgagcaa
    15961 cctgcggcta gtttcctagt ttgctctttg attttcattg agtatcagat ttaggaaatt
    16021 aacttcctcg tctccaaaaa atagctaaga caatcatggc acctaaaaca gctgggataa
    16081 tagctgttcc tgataaaact ggcccccaag ttccaaagag caagtgacct agaaaggctc
    16141 cgatccaacc gagaaacatt tttccaaaac atcccattcg ctctccacga ttggtcatag
    16201 cacctgctaa aaatcccact aggagaccaa cgaacatact tcctaacata ttatctcctt
    16261 aatttgccca attcccatta cggaaaagag gtacccgcgt tccatcctca cgaataccat
    16321 cgatatccat ttggttagaa ccaatcataa agtctacgtg aacatctgaa cggttaagcc
    16381 ctgcagcttc aagctcctct tcgctcatct ccgctccatc aacaaggcta gtcgcatagg
    16441 ctgcaccgat agccaagtgg tttgacgcat tttcatcgaa aagggtgtta aagaaggtaa
    16501 tgcctgactg agaaattgga cttggatctg gtaccaaggc acattcaccc aaggcacgcg
    16561 cacccgcatt ttcaaagaca aggtctttca taacctgatc acccttctca gcagtgatat
    16621 ctacgatttg tccatcctta aagatcacct taatgccttc aatgatattt ccgttgtagc
    16681 taagcggttt tgtagaagtg acataaccat ctgcacgacg gaagtcaggc gctgtgaaga
    16741 cctcttctgt cggcatattt ggcaagaatc cttcgccctg tgcattgaca gcaccagctg
    16801 attcccaaac gtggttcttt ggcaaaccaa gtgttaaatc tgttcctggc gctgtgtagt
    16861 gaagggctga aaattgctcc ttattaagca tatcggcctt gctcttgaga atggctgcat
    16921 gctcttccca ggccttaaca ggatctgctt cgtagacacg gcaagttttg aagatttggt
    16981 cccaaaggag atcgactgct tcttcgtcgc tcgcagcatt tgggaagact ttcttagccc
    17041 actcaagtcc agcagcggct gctacagtcc agctaacctt gttagattga gttgcgattc
    17101 gcattggctt catggcaagt cccatagctt tagcagaagc tgaaagcttg tcagcgtcca
    17161 ctccgttcaa ggcacctgga tcagatgaac gaactccaag acggctagcc ttgttctcca
    17221 agagatagtt catctcagca atcttgtatt ctggcacatt gtccaaacgc tccatcgggg
    17281 catggaggaa tttctcacgg ttaatcacat catctgtcca ctgaacgatg acctcatgcg
    17341 cacccaaggc ataagcttct ttcacgatta gatgtgccaa ttcacgttgc tccacatcaa
    17401 tagagagagc caaagtgtga ccaggttgca cgttaattcc gttcgcaacc aacaatttcg
    17461 catatttttc tagattttct ttaaaatttg gtaaaaccat cctgttttct cttttctatt
    17521 tttatttttc tttcaaagca gaaaagattc ctgctaaagc aatagcacct gacaagagtg
    17581 ctgtcgataa aagaattgta cgatcagcaa gttctaattg atattcaaat accttcttag
    17641 ccggcttatc ttccgcaaat attcttagtt tcatgagaac ccccttaaaa tagattaaaa
    17701 taaatcactg tgactgcctg tcctcagcaa atttaaaatc aattccgact tatctacttt
    17761 ataaaccaaa agccaatctg gctgggtatg gcattcacga actccttgaa aatgcttgga
    17821 tgccgtcaat gaatgatcac gatatctggc aggatgttct ttttcttgaa ccagaaaatt
    17881 caaaacttct tctaataatt ctgccttcaa accacgcttc atagccaact taaaatcttt
    17941 tttaaactgt ttatgataac gaatcttaag cacgtaagtc ctccatcaaa tctgagactg
    18001 attcaaaaga ctggctcata ttacgatttt ggtctaaatc cgttaacact tggagcaact
    18061 tccgattttc gtctagtcta acatcaaaag gtaatccctg atattgaatt gcctgacgaa
    18121 ggaaaatatt aatagctgtt gtcatatcca ttcccagatt actaaacacc tgttgggcct
    18181 gctccttaac ctcactatcc agacggatgc tcatactcat ctttgacata ctctcaccct
    18241 ctttccatag actattttaa caaaaaagaa agctaatgta aatctattgg atatacgtta
    18301 gcctcttcta atagattatt aagcaatttt ttaaaacaac tcatcaaaca aactcaactg
    18361 gttatcctct ggcatatttc caagaatacc catctcatcc atcttttcaa ccaaggttga
    18421 tgagagtcca ccacgcttgc gtagttctgt tttagagagg aattctccct cttcacgcgc
    18481 ccgcaccagt tgcttggcaa cgttctctcc cagaccatcc attgctacaa atggtgggat
    18541 aagggtatcc ccgtcgatga ggaactctgt cgcctgacta cggtagagat ctaatttgcc
    18601 aaacttgaaa cctcgttccc acatctcatt gacaatctca agagttgtat agagatcgat
    18661 ttccacatta gaggcttcat tgttcttccg tttttcagag atttcttcca ttctgcgctt
    18721 gatggcctcc aagcccgcac ccatggtctt gatatcaaaa gccttagcac gaatggagaa
    18781 gtaagcacag tagtaataaa taggatggtg aaccttgaag taagctacac gcaaggccat
    18841 cataacgtag gctgccgcat gggccttagg gaacatgtac ttaattttcc cacaggattc
    18901 gatataccac tctggcacct tattagcctt catggcttcg atatagccat ttctctcctc
    18961 ttctgaaatc tttagccaca aacccttacg tacccgttcc ataatggtaa aggccatctt
    19021 aggttccaga cccgcatgca tgaggtaaac catgatgtcg tcccgacaac cgataacagt
    19081 cgataggtcc gctattcctt gcttaatcag atcctgagca ttccccaacc aaacgtcagt
    19141 accgtgggac agaccagaca gctgaagcaa ttccgcaaag gttgtcggat gggtttcgtc
    19201 taccattcca cgtacgaaat ttgttccaaa ctctggaatc cccaacatac ccgtaggcgt
    19261 tccaatttgt tcaggtgtta cccctagcac atcagtccca gaaaagagtg ccatcacgcc
    19321 ttcgtcatcc ataggaattt cattagggtc aataccagac aaatcctgaa gttttcgaat
    19381 catggtcgga tcatcatgtc ccagtacatc gagtttgagg acgttctcat cgatatcgtg
    19441 gaagttaaag tgagtggtct gccattcagc cgtgacatca tctgctggat actggacagg
    19501 cgtaaaatcg tagacatcca tgtagttcgg aataacaacg attccccccg ggtgttggcc
    19561 tgttgtccgc ttgacacccg ccgctccttg agcgaggcgt tctacttctg catcacgata
    19621 aaacttgcca taatctcgct cgtaaccctt gacaaatcca taggcagtct tggcagctac
    19681 cgtaccaacc gttcccgcac ggaaggcata ttcttcacca aagatatcac gcacatccaa
    19741 gtgggcgcta ggctgatctt ctcccgagaa gttcaagtca atatcaggaa ccttatcccc
    19801 atcaaagcca aggaaggtct caaacggaat atcctgtccg tttttactga gtttgtgacc
    19861 acagtttgga cagtccttat ggggcatatc aaatcctgaa ccgtacgaac catctgtgat
    19921 aaactcactg tactgacact gaccacagac atagtgagga gagagaggat tgacctccgt
    19981 aatcccaatc atggtcgcaa cgaaactaga tccgacagac ccacgagaac caaccaaata
    20041 accccgttca ttagaacgtt gcaccagcat ctgcgatgcc agataaatca cagcaaatcc
    20101 attccccagt atggatgtta attctttttc aatccgcaaa tcaacaatat ctggcagcgg
    20161 atttccataa atctcaaaag ctttcttata ggtcaactca gcaactgttt cttcagcctt
    20221 gtcgatgaaa ggcgtataca agtcaccctt aacgacttca acgggttcaa atatttctgc
    20281 caaggcatta gtgttttcaa taaccagttt acgagccagt tcctctccca aaaaggcaaa
    20341 ttcatccaac atctcattag tcgttcgaaa atgagccttt ggaagtggtg ctggttgggc
    20401 atgttcacca tgaccgatag ttcgattaat catcgcaccc tgtcccaaac tacggacaat
    20461 aatttcacga taaatctctt cttccggttc gatatagtga acatttcccg tagccagaac
    20521 aggcttgcca aggcgatctc caacctctat caaactcttg ataatggtct ggagttcctc
    20581 catatccttg acctgctctt tggcaatcaa gggcgcatag atagccggtg gcatgacctc
    20641 gataaagtca taatacttgg ccacctcaac cgccccatcc acaccttgag aaacgaccac
    20701 gtcaaaaact tcaccctctg aacaggctga acctaaaatc aagccctctc gatgggcatc
    20761 tagaaccgtt ctcggaatcc gtggcactcc ttcaaaatac ttggtattag acaaggaaac
    20821 cagcttaaag atatttttta gacctacctg attcttgaca tagatggtcg catgcttgat
    20881 ccgagctttt ttgtaagaat ctggactgat tagatcaatg ttgagtctag ctaaatcggt
    20941 cacaccatgt ttttctgcta cctctttgat aaagatgaaa agcagacgac cagtcgcttc
    21001 cgcatcgtaa ttggccatgt ggtgatgttc caaggccaca ccaaaacgct tggtcaaagg
    21061 ccccaaacca tggcgtttat actcaggata gaggtttcta gcaaactcca gcgtatcaat
    21121 aactggctga ctaatctttg gaagaccatg acgctcataa ttagcattca taaagccaac
    21181 gtcaaaggta gcattgtggg caactaggac cgtatccttg caaaattctt ggaattcttg
    21241 caaaacttgt tctagtggtt tggcattttt gacatgatca tctgtaattc cagttaactc
    21301 tgtagtaaag gctgacaagg gatgcccagg attgataaat tcatcaaatt cagcaataac
    21361 attccccttg tacatcttag aggccgcaac ctgaatcaag tcattataga tagctgaaag
    21421 tcccgtcgtt tccacgtcaa agaccacgta ggttgcttct gacaagtcca tctccacttc
    21481 gttatagacg atagggacac ggtcctccac gatattggct tccatcccat agatcagctg
    21541 gattcccgct ttcttagccg ccttatagcc atgtggaaag gactggacat tcccatggtc
    21601 cgtgatagca accgccttgt gtccccactt agcagctgtt gcaacaatct cttcgacctc
    21661 tggcaaagca tccatagtcg acatgttagt atgagcatga aactcaaccc gacgctcacc
    21721 ttctggcatc aaatccttcc gctcatagtg aacaacttcc tgcagatcct gtacgttcat
    21781 agtcaaatcg cgtgtgaagt tattcatctc cacattccct cgaactcgga gccaagaatt
    21841 cttcttgatg agatcaaact tctgggcctc ttcctcgttt ttaacccact tttgcataga
    21901 aaaacttgaa gtgtagtccg tcattttaaa gttgattaaa acacgacctg ttctagtcac
    21961 tttttgctcc acatcaaaaa caaccccttc aaataccaga cgattttcct ctgtcgtcac
    22021 ttcgatcata ggagtaatct ccgccttatc cagcttgggt ttagctgcag cttttttcgc
    22081 ttgaaaatca aagactggtt tctcttccgc tggaggaggt gccatctgct ccagttgttc
    22141 catagcacgg agcgcttcct cattggcagc ttgaacaatc tgctcatttt cagcatgaaa
    22201 ggcctcttcc tgctcttggg tcaggacatc attcttatcg acttgacagt taaaagttgg
    22261 aaaaccaaac ttttcaagtt gtttggctaa attaggaaga tgattcttct taaaatgttc
    22321 cttatcaatc gcctcagatc cttcaataaa tagctgatta ccctcagcac gaacttgcaa
    22381 attttgataa agggacttaa aaccttgact agcacatgga ccttcagaga aagcctccct
    22441 atagtaggac tgcaagagct gatttgaaaa ttcttgagac cgagccttaa tttcaaaaac
    22501 agctttattg cctgtcttag aaaattcttc gctcaaacct ttctttaatt ctaaaaagat
    22561 ttcaatcggt aaaatattag aaaatacgaa atgaaactcc cataccttac taattttatg
    22621 aaccacaact cgctcaatat tggcctgtgc taaagcagga gcctgtctca tttcagcagg
    22681 catccccaat tgattcatca aaatttcaaa actatttgac attcattttc ctcacattat
    22741 tcttctacta ttttaccata tttagaggta ttttctaaag acaaaaggaa gccactaagt
    22801 gacttccttc tagagtgagg acggattagt cttcaccttt atttttctta ataatttctt
    22861 cttgtactga cttaggtaca tcttcgtagt ggtcaaatac catcatgaat gtaccacgtc
    22921 cttgagatgc agaacgaaga actgttgcgt aaccgaacat ttcagcaagt ggaacgtaag
    22981 cacgaacgat ttggctgtta ccgtgtgctt ccataccatc tacacgtcca cgacgagcag
    23041 ttacgtgacc cataacatca ccaaggtttt cttctggaac agtgattgtt acaagcatca
    23101 ttggttcaag gatagctggt tgtgctgatt tagcagcttc tttaagggaa agtgaagccg
    23161 caatcttgaa ggcagtttca gatgagtcga catcgtgata tgaaccatca taaagcttag
    23221 ctttaacgtc aaccattggg taacctgcaa gaacaccgtt agccatagat tctaccaaac
    23281 ctttttcaac cgctgggata aattcacgag gaaccacacc accgacgatt gcgttttcga
    23341 attcgaatcc tttaccttct tcgtttggag taaattcaat ccacacatca ccgaattgac
    23401 ctttaccacc agactgacgt ttgaagaatc cacgtgcttg agtagaagcg cggaatgttt
    23461 cacggtaaga tacttgaggc gcacctacgt tcgcttcaac tttgaactca cgacgcatac
    23521 gatcaacaag gacgtcaagg tgaagttcac ccatacctga gataactgtt tcaccagttt
    23581 caacgtttgt ttcaacgcgg aatgttggat cttcttcagc caatttttga agggcgatac
    23641 ccatcttgtc ttggtcagct ttagattttg gctcaaccat caattggata actggttctg
    23701 gaacgttgat tgactcaagg atgattttag atttttcatc tgtcaatgag tcaccagttg
    23761 tagtatcttt caaaccaacg gcagcagcga tatcacctga gtaaacagtg tcgatttctt
    23821 gacggctgtt agcgtgcatt tgaaggatac gtccgatacg ttcacgttta cctttagaag
    23881 tattcaatac gtatgaacct gattgaagaa cacctgagta aacacggaag aatgtcaaac
    23941 gacctacgaa tgggtcagtc atgatcttga aggcaagagc tgcaaatggc tcttcgtcag
    24001 atgctggacg agtttcttca gcgtctgtat ctgggttaat acctttgatt gctgggatgt
    24061 caagtggact tggaaggtag tcgataaccg catcaagcat caattgaaca cctttgtttt
    24121 tgaaggctga accacacaat actgggaaga attcaacgtt gatagtcgct ttacggatac
    24181 cagctttcaa ttcttcgtta gtgatttctt caccttcgag gtatttcatc atcaattctt
    24241 cgtcagtttc agcaactgct tcaatcaatt tttcacggta ttcttgagct tggtcaaggt
    24301 attcagctgg gatgtcttct tcaaggatat ccgtaccaag gtcgttagta tagatttcag
    24361 ctttcatctt gattaagtca atgataccac ggaagtcatc ttcagaaccg attggcaatt
    24421 ggattgggtg tgcatttgct tgaaggcgat cgtgaagtgt gcttacagag taaaggaagt
    24481 cagcaccgat tttgtccatt ttgttggcaa atacgatacg tggaactccg tactcagttg
    24541 cttgacgcca aactgtttca gtttgaggct caacacctga ttgtgagtca agaacggtaa
    24601 ccgcaccatc caatacacga agagaacgtt gtacttcgat tgtgaagtcc acgtgtcctg
    24661 gtgtgtcgat gatgtttacg cggtggttgt tccattgagc tgttgtcgca gcagatgtga
    24721 tcgtgatacc acgttcttgc tcttgctcca tccagtccat ttgtgacgca ccttcgtgag
    24781 tttcaccgat tttgtggatt ttaccagtgt agtaaagaat acgctcagta gttgttgttt
    24841 taccggcatc gacgtgagcc atgataccga tattacgagt tttttcaagt gaaaattcgc
    24901 gtgccatgag gtttgtttct cctatttatt tttgatttct attctattat aacacgattt
    24961 taataaaaac ggataggcag gacctacccg ttctcaatgt tttcatgcta ttgttggttt
    25021 caacttacga gatggtaagc tgagttatag ctaatactaa tcgatttagc taatttgaac
    25081 ccgggctaaa gttagttagc cgatgtgagc tggaacggga tgctgcgtga aaaagataaa
    25141 actccttgta ttcgtcgaat actgcgtcag tttcctattt tcaccttgca tccttaccgt
    25201 tcctagcatc atgatttagt tgagctcaag ctaaaagtct ggagaaaaag atgaatctca
    25261 ttggttgcaa ccgcaacctg cttcgattcc ctattttctc tgggactttc ttaacgcttt
    25321 cgcatcctat cttaccaacg gaagtgtgcg aatgcacggt tagcttcagc catacggtga
    25381 gtatcttcac gtttcttaac tgctgcacca gtgttgttag cagcatccaa gatttctttt
    25441 gcaagacggt cttgcattgt gtgttcacca cgaagacgag cgattgttac caaccaacga
    25501 agtccaagtg ttgtacgacg ttctggacga acttcaactg ggacttggta gttagaacca
    25561 ccaacacgac gtgcacgtac ttcaagtaca ggcatgatgt tttccatagc tgtttcaaat
    25621 acttcaagtg catcgttgcc agtagcttct ttgatttgct caaaagcacc gtaaacgatt
    25681 gaagcagcag taccacgttt accatcaagc ataacgcggt tgataagacg agtaactagt
    25741 tgtgaattgt atagcggatc tggcaatacg tcacgttttg gagctctatt tttacgactc
    25801 atttctcttt atcccctttc cttatgcttt tggacgttta gtaccgtatt tagaacgacc
    25861 ttgtttacga tcgttaacac ctgcagtatc aagtgcacca cggacgatat ggtaacgtac
    25921 ccctggaagg tcttttacac gtccaccgcg aagaagcacc acgctgtgct cttgcaagtt
    25981 gtgtccgata cctgggatgt aggcagtaac ttcgataagg ttgctcaaac gtacacgagc
    26041 gaatttacga agggctgagt taggtttttt aggtgtcatt gttccaacac gagttgcaac
    26101 accacgtttt tgtggtgaag aaacgtttgt ttgaactttt ttatgactat tgtaaccaac
    26161 gttcaaagct ggtgatttag atttttctac ttttgattta cgcggtttgc gaaccaattg
    26221 gttaattgta ggcatctaca ttctcctgtg tttttttatt tttggtgatg atacacttgg
    26281 tgacagatat catctgtgtg tacttttgca acatttgtca gcacgtccct gtacactctt
    26341 gagagaccaa aagtaaaaag taccgtctat tattgtaaca aaattttccc ttgtttgtca
    26401 agatattttt cttttttatt ggtaatgtta gagatcaatt tctgaataaa aatagctggg
    26461 aacacatcat cttcctaata atacggcttg gcttatgtga catttttatc tccgtcattt
    26521 atactgatat ataaaatagt acagaaaact tctcaaaagt aagaattttt ttcacaaatc
    26581 aaagaaaacg cttgcatatt gttttactac atgctatact gatatagaaa tttattgatt
    26641 ggagaatcat tatgagaaaa acaccatctc acactgagaa aaaaatggtc tacagcatcc
    26701 gttccctcaa aaatggaact ggttctgtcc ttatcggcgc aagccttgtc ttgcttgcca
    26761 tggctacacc aactatctca tccgacgaaa gtacaccaac cactaacgaa cccaacaaca
    26821 gaaatacaac cacccttgcc caacctctta ctgatacagc agctggctct ggtaagaacg
    26881 aaagtgatat ttcttcacct agaaatgcaa acgcttccct agagaaaaca gaagaaaaac
    26941 ctgcaacaga gccaactact tctactagtc cagtaacaac tgaaactaag gcagaagagc
    27001 ccatcgaaga taactacttc cgtatccatg tcaaaaaact tcctgaagaa aacaaggatg
    27061 ctcaaggact atggacttgg gacgatgttg aaaaaccatc tgaaaactgg ccaaacggag
    27121 ctttgtcctt caaggatgcc aagaaagatg actacggcta ttacctagat gtcaaattaa
    27181 agggagaaca agccaagaaa attagcttcc tcatcaacaa tacagctgga aaaaatctaa
    27241 ccggcgataa atctgtagaa aaactagttc caaaaatgaa cgaggcttgg ttagaccaag
    27301 attacaaggt tttctcttac gagccacagc ctgcaggaac tgttcgcgtc aactactacc
    27361 gcacagatgg caactatgac aagaaatctc tctggtactg gggagatgtg aaaaatccaa
    27421 gtagcgctca atggcctgac ggaacagact ttacggctac aggcaaatat ggccgctata
    27481 tcgacattcc tcttaatgaa gccgcaagag aatttggatt tttattacta gatgagagca
    27541 aacaaggaga cgacgtgaaa atccgtaaag aaaattataa gttcacagat ttgaaaaatc
    27601 atagccaaat tttcctaaaa gacgatgatg aatcgattta cacaaatcca tactatgtcc
    27661 atgatatccg tatgacagga gcccaacacg taggcacttc tagcattgaa agtagctttt
    27721 caacacttgt cggtgctaaa aaagaagata tcctcaaaca ctccaacatc actaatcacc
    27781 taggaaacaa ggtaactatt accgatgttg caatcgatga agctggtaag aaagtgacct
    27841 acagcggaga tttctctgac acaaaacatc cttatactgt tagctacaat tccgaccaat
    27901 tcactaccaa aacaagctgg cacctgaaag atgagacata cagctatgat ggcaaactgg
    27961 gagctgacct aaaagaagaa ggaaaacaag ttgatttgac cctttggtca ccaagtgctg
    28021 ataaggtttc tgttgttgtc tacgacaaga atgaccctga caaagtagtt ggaactgtcg
    28081 ctctcgaaaa aggggaaaga ggaacttgga aacaaactct agacagcaca aacaaactcg
    28141 gaatcacaga tttcactggc tactattatc aataccaaat cgagcgtcaa ggtaaaactg
    28201 ttcttgcact cgatccttac gctaaatctc ttgctgcttg gaatagcgac gatgccaaga
    28261 ttgacgatgc ccataaagtg gctaaagccg cctttgtaga tccagctaaa ctcggacctc
    28321 aagacttgac ttatggtaag attcacaatt tcaagactcg tgaagacgcc gttatctacg
    28381 aagctcatgt gcgtgacttc acttcagatc ctgccattgc aaaagacttg accaaaccat
    28441 ttgggacttt tgaagccttc attgaaaaac tagactatct caaagacttg ggtgtaaccc
    28501 atatccagct ccttccagtc ttgtcttact actttgtcaa tgaattgaaa aaccatgaac
    28561 gcttgtctga ctatgcttca agcaacagca actacaactg gggatatgac cctcaaaact
    28621 acttctcctt gactggtatg tactcaagcg atcctaagaa tccagaaaaa cgaatcgcag
    28681 aatttaaaaa cctcatcaac gaaatccaca aacgtggtat gggagctatc ctagatgtcg
    28741 tttataacca cacagccaaa gtcgatatct ttgaagacct agagccaaac tactaccact
    28801 ttatggatgc cgatggcaca cctcgaacta gctttggtgg tggacgcttg gggacaaccc
    28861 accatatgac caaacggctc ctagttgact ctatcaaata cctagttgat acctacaaag
    28921 tggatggctt ccgcttcgat atgatgggag accatgacgc cgcttctatc gaagaagctt
    28981 acaaggctgc acgcgccctc aatccaaacc tcatcatgct tggtgaaggt tggagaacct
    29041 atgccggtga tgaaaacatg cctactaaag ctgctgacca agattggatg aaacataccg
    29101 atactgtcgc tgtcttttca gatgacatcc gtaacaacct caaatctggt tatccaaacg
    29161 aaggtcaacc tgcctttatc acaggtggca agcgtgatgt caacaccatc tttaaaaatc
    29221 tcattgctca accaactaac tttgaagctg acagccctgg agatgtcatc caatacatag
    29281 cagcccatga taacttgacc ctctttgaca tcattgccca gtctatcaaa aaagacccaa
    29341 gcaaggctga gaactatgct gaaatccacc gtcgtttacg acttggaaat ctcatggtct
    29401 tgacagctca aggaactcca tttatccact ccggtcagga atatggacgt actaaacaat
    29461 tccgtgaccc agcctacaag actccagtag cagaggataa ggttccaaac aaatctcact
    29521 tgttgcgtga taaggacggc aacccatttg actatcctta cttcatccat gattcttacg
    29581 attctagcga cgcagtcaac aagtttgact ggactaaggc tacagatggt aaagcttatc
    29641 ctgaaaatgt caagagccgt gactatatga aaggtttgat tgcccttcgt caatctacag
    29701 atgccttccg acttaagagt ctccaagata tcaaagaccg tgtccacctc atcactgtcc
    29761 caggccaaaa tggtgtggaa aaagaggatg tagtgattgg ctaccaaatc actgctccaa
    29821 acggcgatat ctacgcagtc tttgtcaatg cggatgaaaa agctcgcgaa tttaatttgg
    29881 gaactgcctt tgcacatcta agaaatgcgg aagttttggc agatgaaaac caagcaggat
    29941 cagtcggaat tgccaacccg aaaggacttg aatggactga aaaaggcttg aaattgaatg
    30001 cccttacagc tactgttctt cgagtctctc aaaatggaac tagccatgag tcaactgcag
    30061 aagagaaacc agactcaacc ccttccaagc ctgaacatca aaatgaagct tctcaccctg
    30121 cacatcaaga cctagctcca gaagctagac ctgattctac taaaccagat gccaaagtag
    30181 ctgatgcgga aaataaacct agccaagcta cagctgattc acaagctgaa caaccagcac
    30241 aagaagcaca agcatcatct gtaaaagaag cggttcgaaa cgaatcggta gaaaactcta
    30301 gcaaggaaaa tatacctgca accccagata gacaagctga acttccaaat acaggaatca
    30361 aaaacgaaaa caaactccta tttgcaggaa tcagcctcct tgcgctcctt ggtctcggtt
    30421 tcttactaaa aaataaaaaa gagaactaaa ctagccctcc tatagaaaaa tcccccaagc
    30481 attatagctc gggggattaa ttttcgtaca atatttgttg tcctaataaa cttgattagg
    30541 attttttatt aagcctcttt catagcaaaa taagctcgta cttttggtgc aacttgtgtt
    30601 ccgaagagtt caatagctct cagaacctgg tcatgaggca tagaaccaag cggtatatga
    30661 agcatgaagc ggtccaatcc taaatcctct atcatgcgaa tcaatttttc ggccacctga
    30721 tctggattgc caacaaacat ggcgccattt ggccctacct gctccaaata ttgctcataa
    30781 cgcaattcct gccagtgcgg acggtctttg gaaatagcat ccaccacttg cttagtcgga
    30841 tggaaataat ctttcaccgc ctgctcacca tcttccgcaa tccaccccca agaatgggct
    30901 cccactttca agtctttgtc agcatggccc gcttcgcttc caatctcacg ataagcctga
    30961 atcaactttt taaaataacg tggattacca ccaataatag catatacaat cggtagacca
    31021 gcctgagcaa tcttcactgt tgattcgaca tgaccacctg tagctatcca caagggcaat
    31081 ttgtcctgaa ctggacgagg ataaacttct ttaccagcaa tcgtttgagt caatcgacct
    31141 tgccagtcta acttggtctt ttcattgact aactgaagca agtctaattt ctcatcaaaa
    31201 agagagtcgt agtctttcaa gtcataacca aacagaggga aagattccgt gaaagagccc
    31261 cttccagcca taatctccga tcgtccatct gacaaagcat cgatagtggc atactgttgg
    31321 aacaaacgaa tcgggtccat gcttgacaga atgctgactg cactggtcaa acggattttc
    31381 ttggtattga ctgccccagc ggccaggaca atctctgggg ctgatactgc aaaatccgcc
    31441 cgatggtgct cgccaatccc atatacgtcc aaaccaacct tgtcagccag ctcaatctct
    31501 gccaccaact ggcgaatgcg ttcagcatga ctgtaagttt gtccagtccc ttcaagctcc
    31561 gttatttccc caaatgttga aattcccaat tctaccattg tgattctcct tgtctatctc
    31621 tgtacttcaa tttgaaaaat tattctaata ctcaatgaaa atcaaagagc aaactaggaa
    31681 gctagccgca ggttgctcaa aacagtgttt tgaggttgtg gatagaacta acgaagtcag
    31741 taaccatacc tacggcaagg cgacgttgac gtggtttgaa gagattttct aagagtataa
    31801 cacgaatctt gagtacaagc aaccaatttg ctcacaagaa aaagcctaga taactagact
    31861 tttttagctt attctaccgt tactgacttg gcaaggttac gtggtttgtc cacatcgagg
    31921 ccacggtgga gggttgcaaa gtaagcgact aattgcgtcg gtacgaccat tgaaattggt
    31981 gagaggtatg gatgtacggt cgtaaggacg atatcgtcgg tatctttggc tacattctct
    32041 tctgcgatag tgaggacttt ggcaccacgg gctgcgacct cttggatatt tccacgagta
    32101 tggttggcaa gaactggatc tgacaagaga gccaaaacag gcgttccttc ttcaatcaag
    32161 gcaatggttc cgtgcttgag ttctcctgcc gcaaaacctt cacactggat ataagaaatc
    32221 tctttgagtt tgagacttgc ttccatggct acgtagtaat cttgaccacg tccgatgtaa
    32281 aaggcgttac gagttgtttc aagaagttca cgaaccttgg cttcaatggt ttctttctct
    32341 gaaagagttg attcgataga ctgagctacg attgacaatt catgaaccag gtcaaaggct
    32401 tgcgctttag cattaccatt tgcttctccg actgcttttg caaggaaggc aagggctgcg
    32461 atttgcgctg tataggcttt agttgatgcc acggcaattt caggacctgc gtgaaggagc
    32521 atggtatagt tggcttcacg tgagagggtt gaacctggaa cgtttgtcac tgttaagctt
    32581 ggaattccca tttcattagc cttgaccaaa acttgacgac tatccgctgt ttcaccagat
    32641 tggctgataa agatgaagag tggtttcttg ctgagaagtg gcataccgta gccccactca
    32701 gatgagattc caagttcaac tggtgtatct gtcaattctt ccaacatttt cttagaagca
    32761 aatcctgcat ggtaagatgt tccagctgca aggatgtaga tgcggtctgc gtcttgaaca
    32821 gccttaatga tatctgggtc tacgacaact tgaccagcct catctgtgta ggcttggatg
    32881 agtttccgca taacagttgg ttgctcgtca atttccttga gcatatagta agggtaagtt
    32941 cccttaccga tatctgacaa gtcaagttca gcagtgtagc tagcacgctc acgacgattt
    33001 ccatcatagt cttgaacttc cacactatca gccttgacga ttaccaactc ttggtcatgg
    33061 atttccatgt attggttagt ttcacgaatc atagccatgg cgtctgagca gaccatgtta
    33121 tagccttctc caagaccaat caaaagtggt gatttatttt tagctacgta gatgacttca
    33181 ggatcttgtg agtcaaccaa ggcaaaggca taagaaccac ggatgatgtg aagggctttt
    33241 ttgaaggctt caagaactga gagcccttct tcttccgcaa attttccaat caaatgaacg
    33301 gctatttcag tatctgtctg ccccttgaag tggtgacctg caaggtattc ttccttgatt
    33361 tcaaagtagt tctcaatcac cccattatgc accaagacaa aacgttctgt ctcagagcgg
    33421 tgtgggtgag cattgtcctc agttggtttt ccgtgagtag cccaacgagt atgtccgata
    33481 ccagttgttc cctcaacacc agctgtcttg gcagacaatt ctgcaatacg accaacagcc
    33541 ttcaccaaat ggttatcagc accatctagg acaaaaattc ccgcagaatc atagccacgg
    33601 tattcaagct tttcaagccc ttgaatcaaa atatcagttg catttgtgtt tccaacaaca
    33661 ccaacaattc cacacatagt atatacgaca caggcaagct gtgctttctc cttaaaattg
    33721 gtatagtcta attcatcttt tatagaatca gcaaaaacag tatatacttg tttctttcac
    33781 ttgtcaagag taaaaattgg tatagttcaa attaagctcc tgtaagcata aaaactctga
    33841 ccgattggga taatcagtca gagtcctttt taaaatccat tattatcgct taattctttg
    33901 aaccagtggc ctgatttctt cagacgacgt tcttgcgttt ccaagtctaa ttcgaccaaa
    33961 ccatagcgat ttttatagct gttgagccat gaccagcagt caataaaggt ccaaatcaag
    34021 tagcccttac agttggcacc atcttcaatg gcacggtgaa gttcacgaag atgacctttt
    34081 acaaagtcaa tacggtaatc atcttgaatc attccatctt gacggaattt ttcttcccct
    34141 tcaacaccca taccattctc agtcaacatc cactcaatat tgccataatt ttccttgata
    34201 ttttgggcga tgtcataaat cccttgctca taaatctccc aaccacggtg agaattgatt
    34261 ttacgtccag gcatcacata aggctcgtaa aaatgttctg gtaagagtgg actatctgga
    34321 tgcttagcaa atcgaggagc cataacacgc aaaggttgat agtagttcac accaaggaag
    34381 tccaccgtat tatcacgaat gagttccaac tcttcctctg tagcatcagg taaaagaccg
    34441 tgttcatgca agatttctac caactcctgt ggataagtcc ccaagacaga tggatctaag
    34501 aaagattggg cctgaaaaag ggccgcaata cgagctgcct tgacatcagc aggatgctgg
    34561 ctacgtggat aagccggtgt caagttgagg acaatcccaa tcttggaatc aggcaaaagt
    34621 tcatggcaag ccttaacagc ccggctgctg gccaattgtg tatgataggc taccttaaca
    34681 gctgcctctg catccacctt atgtggacaa tgggcatcat aaaaataacc aaattctaca
    34741 ggaacgatgg gctcgttaaa ggtaatccat tgatccacta aatctccata agtctcaaaa
    34801 caaaaacgag catagtcttc ataggctgag actgtcgcct tattttccca accatcacca
    34861 tcctcttgaa gggcaaaagg taaatcaaaa tgatagagat tgactaacag acgaattcct
    34921 ttagccttaa tagcctcaaa gaccttacga taaaaatcca caccttgagg gttgactttc
    34981 ccacagcctt gtggaaaaat ccgtgaccac tgaatagaag tccgaaagac tgtgtgacca
    35041 gtctctaaca aaagctcaat atcccgctcc caattttcat aaaaagtcga tgtcttatct
    35101 gaaccaatcc cattatagta acgatttggc tccacttgga accagtaatc ccagagattg
    35161 tctcccttac cgtcaccagc tacacgtcct tctgtctgcg gtccagaagt agaggatccc
    35221 cagacaaaat cctttggaaa tcttagcata acatttacct ctttatctac tcatttctcc
    35281 cattatacag aaaaaacaag gtaaaaacta gttacatttt ttccttgttt ttcttctgat
    35341 tatagttttt atttcttgct taggatttca agcgtttcaa gcacgttatc tgcatgaacc
    35401 tcaatggtgt caccagttgc cttgatctta acttctacaa tgccatcggc cgctttttta
    35461 ccaacagtga tacggattgg aagaccaatc aagtcactat cgctaaattt aacaccgaca
    35521 cgttcgttac ggtcatctgt caagacttca taaccagctc ccatcaagct tgcttcaagt
    35581 ttttctgtca aggcttgcgc ttcttcatcc ttgacattaa cagtaatcaa atgcacatca
    35641 aatggtgcca attctttagg gaaattgatt ccccaagcgt aacggtattc accttttggc
    35701 gttttgttaa caaagaggcg agcgtgttgc tccatcactg ctgaaagaag acggctgaca
    35761 ccgataccgt aacatcccat gatgattggc acagcacgac cattttcatc caagacatct
    35821 gctcccatgc ttgctgaata gcgagttccg agtttgaaaa tatgaccgat ctcaatacca
    35881 cgcgcaaagt taaggacacc ttgtccatct ggggaaattt caccctcacg aacttcacgg
    35941 atatccacat attctgcagt aaaatcacgg cctgggttca caccagtcaa gtggtagcca
    36001 tcttcgttag caccgacaac tgcattgcga acatcttgca ccttacgatc tgcaataatt
    36061 ttaatattct ctggcaaacc aactggtcca agtgaaccaa atcctgcttg aacaacattc
    36121 gccacttctt cttcgctagc aacgtcaaag aaatctgctc ccaagtgatt tttcaacttg
    36181 acttcgttga gttggtcatt tccaactaga agggctgcaa caagctcacc atctgcaatg
    36241 tagaagaggg ttttaatcgt ttgttcttct ggaacattga ggaaagctgc aacttcatca
    36301 attgatttaa catctggcgt tgcaacacga gtaacttctt cttcagcgac aacacggttg
    36361 cttggtttgt actcgtttgt tgccatttct aagttagctg catagctaga ctcacttgag
    36421 taagcaatgg tatcttcacc agagactatc catttgagca attctgcctt gatttcttct
    36481 tgcacttctg caggaatttc gtcaaatgag gcaactgact tgtccaagac aacccagcgg
    36541 tcaaggtctg tacgagcaga tgtaatggcc ataaattctt ggctatcctt accacccatg
    36601 gctccaccgt caccaataat agccttgaag tctaaaccac tacgagtgaa aatacgctca
    36661 taagctgctt tgtactcatc ataaacacta tccaaactat catagttagc gtggaaacta
    36721 taagcatcct tcatgataaa ctcacgtgta cgaagaagtc cattacgcgg gcgtttttca
    36781 tcacgatact tgggctgaat ttgataaagg ttgagtggca attgcttgta agatttaaca
    36841 gaatcacgga caatagctgt aaaggtttct tcgtgagttg gacctaagat aaagtctgat
    36901 ttttcacggt tttttagttt gtaaaggtct tcaccatagg tttcgtaacg acctgattca
    36961 cgccacaatt ctgcactaag aagggctgga gccaacatct caacagcacc aatcttttcg
    37021 aattcttggc gcatgatgtt tttagctttt tcaatcacac ggttggcaag tggtagataa
    37081 gaataaacac ctgctgaaac ttggcgaaca taaccagcac gcaacataag agcatggctg
    37141 ataacttgag catcgcttgg catttcgcga agcgttggga taggcatttt actttgtttc
    37201 ataatattcc tcgattatct aaaaaagagt cgcataatgt cattccaagt cacagcaatc
    37261 atcaagacaa ccatgatgac cactccggcc aaggtgacat aggtttcaat ttcttgtttc
    37321 aatggtttgc ggcggatggc ttctaggata ttgagcacaa tcttaccacc atccaaggct
    37381 ggaatcggaa taagattaaa aatcccaata ttgatggaaa tcattgccaa gaagtacaag
    37441 atattttcaa ttccattttt agcagcatca ctacttgcct taaagatagc aacaggtcca
    37501 cccaacttgt tcaaatctgg ttggaaaatc agatttttca gagctgagag aattcggaga
    37561 gctgagtcag cagcagttgt aaaaccacct acaaacatgg atagaaaatc tgacttaccc
    37621 cccggttgaa cacctagaag gtaacgacct tgactatctt tgggtgtaac agtgacttgt
    37681 ttgtcactcc ccttttcaga aatagtcaca tccaaagtcg gtgccgtctt atctttggtt
    37741 tctgtttcca cagcttggat caagctttcc cagttgctaa cctcatgtga gccaatcttg
    37801 gtaatttgtg ccgtttctgg tactcctacc ttggccaagg caccttgggg catgatatgg
    37861 aactgattgg tatcaacatc tctgacacca ccctgcataa agattaaaac ccaaaaaaca
    37921 acgacaccta agataaaatt gttcatagga cctgcaaaat tggtaatcag tttgccccag
    37981 atagtcgcat tttgatattg aacatctaaa ggtgcaatcc gaacctcagt accatctgct
    38041 tccacaaccg ttgcatcgtg atccactgca aatgtttttt cttcttccag aaccaatcct
    38101 ttgataaaga gcttgtcttc aaaatcaaac tgggtcacct gcatagggag gactgtttga
    38161 tccaattttt tacctgagag attgatgcgt ttaaccttac catcatcagc aagtgtcaaa
    38221 ctaacaggcg ttcctgtctt gatttcagtt gtatcatcac cccaaccggc catgcggaca
    38281 tagccaccca gaggcaagat tcgaatggta taggccgttc catccttgcc aatgtgagca
    38341 aaaattttag gtcccatacc gatggcaaat tcacgtacta aaatccctga tttcttggca
    38401 aagtagaagt gcccgaactc gtgcaccact acaataatcc caaaaactag aataaaggtt
    38461 aaaattccaa gcatagtgtt tcctccgtct tttgattaaa agagtccaaa taagtgcatg
    38521 attggaaata caagcaacat actatcgaaa cgatccaaaa caccaccatg tccagggata
    38581 aatttcccag aatccttaac accaaaatga cgtttgatcg aactttctag taaatcacca
    38641 aattgtccag caatgctaaa gaaaatagca aagactgaca tcttgtaaat tccatatgga
    38701 agagcaactg tactgtcaac tatcataaag ataatggtta ctaaaattgc tcctaaaata
    38761 ccacccaagg caccctcaag ggttttatta ggcgataccc ttggtgctaa ctttcgtttc
    38821 ccatagttca tcccaacaag ataggcacca ctgtctgtcg cccagacgat acacaaggct
    38881 aagagagcct tgtccaaacc tgcaacacga gcatctagta aagcattaaa tccaaagccc
    38941 acgtagaagc tcatagcaag agggaaaacc gcatcctcaa tcgtataaga cttgctaaaa
    39001 acggtcgttc ctaacatgat tgaaatcaaa acactatagg caaccacatt cccatcaact
    39061 ggcaaaaaag tcaggtaatt ctccaaggga atggtcaatg caaaggttgc aaagagggtc
    39121 aagaggccct ccatcgtcat ggtctctaga cctctcatct tcaaaagttc atgcatggct
    39181 agcatggcta tgattccgat tgctatctga agcaagaggc ccccaatcat taaaattggt
    39241 aggaaaatag ccagggcaat ccctgcaaac aaggttcttt tctgtaaatc ctgggtcata
    39301 tttcctccta aactcctcca aatcggcgat gacgacgatt ataggcaaga atagcttcct
    39361 gcaaggccgc ttcgtcaaaa tcaggccata aggtgtccgt aaaataaagc tcactatagg
    39421 ctccctgcca tggaaggaaa ttgctcaaac gtaattctcc actagtacgg ataatcaagt
    39481 ctgggtctcg taagtcctta ggcaaatgct gagtaaagag atagttacca atcaattcct
    39541 ctgtgatgtc acctgggttg attttggcat ctaaaacatc ctgggaaatc aacttaagcg
    39601 cctgtgtaat ctcagcacgt ccaccatagt taagagcaaa attaagaatc aatcctgtgt
    39661 tgttcttagt caattcctca gccttggtta aagcttcaaa ggtttgctta ggcaggcggt
    39721 ctgtctcccc aatcatttga atcttaacat tattcgcatg tagttccggg acataattat
    39781 cataaaactc tactggcaag ttcatgataa acttgacttc ctgatctgga cgggtccagt
    39841 tttccgtaga aaaagcatag accgtaataa ccttgacgcc cagtttgttg gctgccttgg
    39901 tcacggtttg caatgcttcc atgcccgcct tatgtccaaa aactcgcggt tgcatacgtt
    39961 ttttagccca acggccattg ccatccatga tgatgccgat atgagcagga acctgtgtcg
    40021 gaacctctac ttccacagcc ttatctttct taaaaaatcc aaacatgatc ttattcctat
    40081 tcaaaaatct atcgtttcat tataccatat ttccccattt tcttctatca ctaagctatt
    40141 tattctcagg caccatgccc atttttcaaa aaaataagcc gcctgattgg gcgactttat
    40201 ttttataggg agattattat gaaaaagttt taggagttta agttaaggtc ttcttaactt
    40261 atgaacttag tgtacactcc ctagcttaaa gtttccttaa gtatttttaa aaatcaaatt
    40321 tttccatttc tcctgccaat ttttcttgga taaacgtgtt tgatagagtt ccattcggtc
    40381 ttcattttct aagaaatgag gagttggacg aacttgaaaa ttcaaaatat cctccaaacc
    40441 ataaggtgca tagagttcaa aatctgattc ttcattcaag cgcagtccaa ctgccgtaca
    40501 ccgttctgga tacttactca tagcatcacg agaactggta taggaagcag tgtgaggact
    40561 gtgctggtgc atatagacct gatttttcaa ttcccactgg tactgaggaa aatcctctct
    40621 cagctttttc tccagtaata aggtttcctc ataagaaaaa tctggatcaa agaaaatcac
    40681 atctatatct gtttcatgat caaaagggga tttgtctgac aaaagattcc agatgaaatt
    40741 tctgacagaa cctgctgcca actacgagtc tttcaaacca aggtctcgga tgatcgtcag
    40801 aatggccatc atatctggat tttctctaaa agcctctaag atttcttgct tatttttcac
    40861 tgtattcata acctaagtgc tcatatgcct tagcagtcgc cacccgtcca gaccgtgtcc
    40921 gcatgataaa acctttttga atcaagtaag gctcatacat gtcttcaact gtctcacgct
    40981 cttcggcgat attgacagaa agagttccta gaccaacagg tcctccactg tacatctcaa
    41041 tcatggtacg aaggattttt tgatccacat agtccaaacc ttcatggtca acatccagca
    41101 tagtcaaagc cttatcggta ataatatcat cgattacccc attccccatt atctgggcaa
    41161 aatcgcgcac gcgcttgagg agacgattgg caatacgagg ggttccacga ctacgtaggg
    41221 ccaactcaga tgctgcctca tgagtgattt ccatctcaaa aatatctgcc gtccgctcga
    41281 caatttctgt caagtcagca tgggcataat actccatatg acctgtaatc ccaaaacgtg
    41341 cccgtagtgg atttgagagc ataccagccc gagtcgtcgc accaatcaag gtaaaaggag
    41401 gcaactccaa atgaacactg cgactgcctt caccagcccc aatcataata tcgatgtaga
    41461 agtcctccat ggcactataa agcacttctt ccactgacat gggtaagcga tgaatctcgt
    41521 caataaagag gacatctcca ggctctaact cattcaaaat cgctaccaaa tcacccgctt
    41581 tttcgataac aggaccagac gtttgcttga gattgactcc cagttcattg gcaatgacaa
    41641 aagccatggt tgttttccca agccctggag ggccaaataa gagcacatga tccagcgctt
    41701 catcccgcat tttagcggct tcgataaaga tctgaagctg atccttaacc ttatcctgac
    41761 caatatattc acgtaaatac tgaggacgga gcgtgcgttc tactaactcc tcatcaccca
    41821 tcatctcatt atctaaaatt ctactcatgg ctctattata tcaaaaaaac aagccacaaa
    41881 caaaaaagcc acctgattgg gtgactccta agtttagcac ttatgtggta taatattata
    41941 cggcacttct acaccgccta cgaaaggagg tgagatagcc catgatggaa ttagtactca
    42001 aaactatcat cggaccaatt gtggtcggtg tcgttcttcg tatagtcgat aaatggctaa
    42061 acaaggacaa atagtgtcaa aaaagacctc aagcttattt ggtcgtgagc ttggggtctt
    42121 ttctagccta tgatatagaa ctagtactca attccttttt attatcccat agttcacgaa
    42181 ttttgtcaaa ggtttacatt ttcttcaacc gctgtacgac aagacggtta agattaagag
    42241 aacgttaggg attctatcaa tttcatagaa attttgattt cgtaaacgaa gagacaatct
    42301 tacatgtcac ttctcattta atacgccact actagacaag caaaatcatt attacagtag
    42361 ttccagttct tcaattaaca gtcacttaca atcaaattga gtttgaacta gctgaagcga
    42421 ccacagacct atttcttagt tatattcgct aaaaaagtcc ccgccaattc cccgaccaaa
    42481 atccgaaaaa taccgaaaaa tatcgaaaaa ttatttttag aatagtcccc aaaagcctga
    42541 aatagagcta aaaaactcca cctgattggg tggagttaag ggagattatt atgaaaaaga
    42601 aaagtttagg attt
//
LOCUS       DAVIME010000015        41973 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVIME010000015 DAVIME010000000
VERSION     DAVIME010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.015"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            109..543
                     /locus_tag="VV588_000830"
     CDS             109..543
                     /locus_tag="VV588_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7083202.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            555..1745
                     /locus_tag="VV588_000831"
     CDS             555..1745
                     /locus_tag="VV588_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU7083203.1"
                     /translation="MIKKVTIEEIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1756..2247
                     /locus_tag="VV588_000832"
     CDS             1756..2247
                     /locus_tag="VV588_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU7083204.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2262..3041
                     /locus_tag="VV588_000833"
     CDS             2262..3041
                     /locus_tag="VV588_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU7083205.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3028..3846
                     /locus_tag="VV588_000834"
     CDS             3028..3846
                     /locus_tag="VV588_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU7083206.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3846..4139
                     /locus_tag="VV588_000835"
     CDS             3846..4139
                     /locus_tag="VV588_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU7083207.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4161..6062
                     /locus_tag="VV588_000836"
     CDS             4161..6062
                     /locus_tag="VV588_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU7083208.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYLVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLNSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6122..7123
                     /locus_tag="VV588_000837"
     CDS             6122..7123
                     /locus_tag="VV588_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU7083209.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7233..7568)
                     /locus_tag="VV588_000838"
     CDS             complement(7233..7568)
                     /locus_tag="VV588_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083210.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7579..7821)
                     /locus_tag="VV588_000839"
     CDS             complement(7579..7821)
                     /locus_tag="VV588_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083211.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7837..8031)
                     /locus_tag="VV588_000840"
     CDS             complement(7837..8031)
                     /locus_tag="VV588_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7083212.1"
                     /translation="MNRVKEFRKELGISQLELAKNIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8197..9147
                     /gene="rsmH"
                     /locus_tag="VV588_000841"
     CDS             8197..9147
                     /gene="rsmH"
                     /locus_tag="VV588_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU7083213.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DRKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            9159..9476
                     /gene="ftsL"
                     /locus_tag="VV588_000842"
     CDS             9159..9476
                     /gene="ftsL"
                     /locus_tag="VV588_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU7083214.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            9480..11732
                     /gene="pbpX"
                     /locus_tag="VV588_000843"
     CDS             9480..11732
                     /gene="pbpX"
                     /locus_tag="VV588_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU7083215.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11734..12714
                     /locus_tag="VV588_000844"
     CDS             11734..12714
                     /locus_tag="VV588_000844"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU7083216.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLFAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            13277..15382
                     /locus_tag="VV588_000845"
     CDS             13277..15382
                     /locus_tag="VV588_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU7083217.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMSQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFNILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGNFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(15678..16160)
                     /locus_tag="VV588_000846"
     CDS             complement(15678..16160)
                     /locus_tag="VV588_000846"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU7083218.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16255..17739)
                     /locus_tag="VV588_000847"
     CDS             complement(16255..17739)
                     /locus_tag="VV588_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU7083219.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPGGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMSERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            17892..19499
                     /locus_tag="VV588_000848"
     CDS             17892..19499
                     /locus_tag="VV588_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU7083220.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            19664..19831
                     /locus_tag="VV588_000849"
     CDS             19664..19831
                     /locus_tag="VV588_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU7083221.1"
                     /translation="MKKRILSAGLTFTSDLLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(19824..20674)
                     /locus_tag="VV588_000850"
                     /pseudo
     CDS             complement(19824..20674)
                     /locus_tag="VV588_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            20927..22372
                     /gene="cps4A"
                     /locus_tag="VV588_000851"
     CDS             20927..22372
                     /gene="cps4A"
                     /locus_tag="VV588_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU7083222.1"
                     /translation="MSRRFKKSSSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     IDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVLEIDDSSLAVVKAAIQDVMEGR"
     gene            22374..23105
                     /gene="cps4B"
                     /locus_tag="VV588_000852"
     CDS             22374..23105
                     /gene="cps4B"
                     /locus_tag="VV588_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEU7083223.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRIIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            23114..23806
                     /gene="cpsC"
                     /locus_tag="VV588_000853"
     CDS             23114..23806
                     /gene="cpsC"
                     /locus_tag="VV588_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU7083224.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRDQGDKPGLTNQDLQAGSYLVKDYREIILSQNVLEKVATNLKLD
                     MPTKTLASKVKVTVPTDTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLQIP
                     LLGVVPDLNKMK"
     gene            23816..24505
                     /locus_tag="VV588_000854"
     CDS             23816..24505
                     /locus_tag="VV588_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEU7083225.1"
                     /translation="MPTLEISQAKLDFVKKAEEYYNALCTNLQLSGDDLKVFSITSVK
                     LGEGKSTTSTNIAWAFAHAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEVGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            24521..25888
                     /locus_tag="VV588_000855"
     CDS             24521..25888
                     /locus_tag="VV588_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU7083226.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGCFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            25919..27091
                     /locus_tag="VV588_000856"
     CDS             25919..27091
                     /locus_tag="VV588_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU7083227.1"
                     /translation="MKQSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNGAICYNIDVPNIGPARAIAYDIAAVNKAIELSKGNKDEAPIF
                     YILACRIGPFISGLKKKIRSIGGRLLVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKHA
                     DLLVCDSKNIEKYIREDYKQYQPKTTYIAYGTDTTPSSLKSEDAKVRNWYREKGVSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSNKDFVLITNVEQNKFYDQLLKETGFDKDLRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWKKDELAHVIEEVERFDEGDITELDEKSSQRIADAFTWEKIVSDYEEVFTV"
     gene            27088..28371
                     /locus_tag="VV588_000857"
     CDS             27088..28371
                     /locus_tag="VV588_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU7083228.1"
                     /translation="MKILHYTLGFQPSRTGGLVKYAEDLMTQQATDGHEVIALYPGEI
                     SIIFRQVRIKKAENRKFQCYKIINSLPLALFGGISEPDEFMKSCDKASYRKFLKNIKV
                     DVIHIHSLIGLHKEFIEVAKELGIKTVFTSHDYYGLAPVPHFYFNGVDYSSNNTNLAW
                     NIMSSNALSVKKLRFFQVSFYPTIRKLMKMLGKNPKSKKNLVIRDITEAIDYSALRSY
                     YKAMFGLIDAYLFNSQLAKEVYEANHIIPKNNIIVSISNSSISNHNIRVSSGEKTVVA
                     YIGPDEEYKGYFDFLDIVNDLDQEKYDIKTYGHFPNEDCPPYIQQNGYFTKDTVGSVY
                     SNIDILIVPSRWKETFGLISIEALSYDVNVFVSKNVGSKDLVSEEHIFHNKDDLLKKI
                     QYVKFENVKFKTMKEHMVEIINYYERITNDNQKIN"
     gene            28349..29038
                     /locus_tag="VV588_000858"
     CDS             28349..29038
                     /locus_tag="VV588_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HEU7083229.1"
                     /translation="MIIKRLIKTITGKEIDLHPDIPITYILQRGFQYGLGLSRGLLRG
                     IGLGKKGKRLFIGRGVTLLAKRKLYVGNNIRIGKYVSIDCLSKDGIQIADNVKIGDYS
                     QIIGTGSVKNMGIGLKIGKNSSFSEYSLFGSAGGITIGGDVIAGQNVRFHAENHSYEV
                     LHIPIREQGVNRKGISVGDNCWIGAGAVFLDGSSIGSGCIVATNAVVTKKFPDNVIIG
                     GVPAKILMERK"
     gene            29082..30317
                     /locus_tag="VV588_000859"
     CDS             29082..30317
                     /locus_tag="VV588_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU7083230.1"
                     /translation="MKIAVVGTGYVGLSISVLLAQHHHVVAVDIVKEKVELINKRISP
                     IQDDFIERYLSESNLDLVATIDAETAYKDASFIVVATPTNYDLERNFFDTSTVESVIQ
                     QVQNMNSTATIVIKSTVPVGFTDSIRKKLGISNLLFSPEFLRESRALYDNLYPSRIIV
                     GTDLSNQKLVEKAQVFSNLLVQGAIKKDIPILTMGFTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEIKGLDTQKIIEGVSLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYKNVPE
                     ELIGAIVRSNTTRKDFIANQVLKVVNYNIPEDDIPTKQMEKEVVIGIYRLTMKSNSDN
                     FRQSSIQGVMKRIKDRGVKVIIFEPTLKDSDTFFGNAVINDLEEFKVKCDVIIANRYD
                     ETLNDVKDKVYTRDIFRRD"
     gene            30268..31449
                     /locus_tag="VV588_000860"
     CDS             30268..31449
                     /locus_tag="VV588_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU7083231.1"
                     /translation="MTLRIKYIHEIFLEEIDKNMKKVLIVRSGPYQVNPEGYNLQELG
                     LASAISQQGYQCDVMYYHKTKNYDQLYEKNGEQIKIFWRRGIRLFRSGIYPQILREKF
                     LNQYDKIIISEYSQIMAVLLSRIHSNVYIYNGPYYNLFKIPIIEPIYDFLFVEMLNKR
                     TKTVFCKTEKAECYLKNKGFNDCKVVGVGLDIEKFEQEEEPTEDTIELLRRMENKQNI
                     LYVGSLSKRKNTAQLIRIFNILKSKSGKKNELQLVLIGKDEDNIVEKINYSRFKDDII
                     YQPYLKNSQLQFIYPSSQLLVLPSVQEIFGMVLLEAMYFKLPVVSSASAGGETLIQDG
                     INGKIVNDFNDEHWVDCIENLLNNPLELKRLGECAHKRITEQFMWSSIARKIIETFDE
                     R"
     gene            31458..32300
                     /locus_tag="VV588_000861"
     CDS             31458..32300
                     /locus_tag="VV588_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU7083232.1"
                     /translation="MNFCFVILHYRTSNDTIECIKSIQKLEGDYKIVIVDNASQNGSI
                     ERVEALFANNDEIVIIKNTKNLGFAAGNNIGYAYARTQIKADMIAVLNNDIVIKQKDF
                     INRIFELYRNSQFHIAGPDIVSLVDGHHQSPVVEKINSISKANKELFKYRILRIINKI
                     GLYELMTRQPKKELNRISVADPMRYQENVILHGSFVIFSPLYVSEEECAFRPDTFMYM
                     EEPILYEYCMLKNYKTVFDPSIVIYHKEDSSTNSLYNAAYAKREFVFKNMIRSLKIYR
                     SLLK"
     gene            32342..33610
                     /locus_tag="VV588_000862"
     CDS             32342..33610
                     /locus_tag="VV588_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEU7083233.1"
                     /translation="MLALTIGTVVFVKKTYRTFLNPIILFVILWFIITTLSSLKLFQL
                     FEISTHTQQIILLGTSLFVIGGGIAIWFRDKFYFKVGGNSYFTTDFEINYNLFFLLGI
                     ICLFYYLPDFFSSLVSLIRGGNLNLVRQSAQDAVDTSGLKNFIGTFIVSPSAMVLEIL
                     GVLDFWSNKKGRKLFYLSLAVIFVRVIADAGRTPLFNVVIYLLLTVLANRFSEKTEKK
                     RKVSKIKIVNYGMLGSIILWLSTLSRTTTSVYRILYFYFAMSPILLEKWSSVLDSEKL
                     VTKGLVSLNGFFFSISYVLKNLFRIDYSQRVLEAYTMIANTDAIWYNIAPGLTKANAY
                     VSLFWFFYADGRLLGVLIGSLLYGTFCGYIFCRYIQQQNKKNLAMLLFIYQGVFFSFI
                     RFPFSKSNYAIAFVLLLFFAFKKKGIEKSV"
     gene            33603..34610
                     /locus_tag="VV588_000863"
     CDS             33603..34610
                     /locus_tag="VV588_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083234.1"
                     /translation="MFNINDQSIIYVACPYFNKTGGTELVHQLVYSINHFGGKAIVAY
                     YGSESAPNKVNPAFREYVSTFVDIKDVIDSLDNIIILPEINPDLAANLESIQKAVWWM
                     SVDNYLKRNGILGSLEHFGLLRTIKLFVKGNIKIGGYRIDKEIPHLYQSEYAKQFLLA
                     KGVKKYYRLSDYLNESYIQRSISTDTKKDVILYNPKKGIEFTRELIKQAPELTFSPIE
                     NMSTEQVKKLLSKSKVYIDFGNHPGKDRFPREAAISGCCVITGKRGSAKYYKDIPIPD
                     SYKFEDTVENIPNIIETLKSCLKNYDKHTVDFEKYQQYIKSEHDLFERDVKELFTRNR
                     G"
     gene            34615..36057
                     /locus_tag="VV588_000864"
     CDS             34615..36057
                     /locus_tag="VV588_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEU7083235.1"
                     /translation="MSTRNSLIKNSLYNVAYRMLNIIFPLVSATYTARIILASGVGEV
                     SFAQNVVSYFTTIAAMGIPNYGIREIAKTRNKAEATNKVFSELFLINGLSTLLCSIVY
                     LILILTFNSIFDNTSMYLAVGLTLVFNFLNIDWFYQGKEDYAYITKRSFSIKLISLFS
                     LFIFVRDTDDAVNYALISSLAIGGNNIFNLVNLRKYNIRFSFNNIKIRRHLKPIFVLL
                     GSVIAIEIYTMLDTTMIGAMVGTTEVGYYTNSMKLVKLLITVITAIGGVLLPRLSDYY
                     SKGEFEKLNHIVDKVFRIMLFLFLPAQVALILVAPVIMPILFGDSFIPAVLTLQLTSL
                     LICTLGFSNLFGTQILLTFGDERKLLISTILGALSNIALNLILIPVMAQNGAALASVI
                     SETIVTLTAYYYAKKRVTIRFDLGFYLPTVVSTIIMGGAIYVVMQLYIGDIEKMLFST
                     LLGGVVFLLINVFMKNPIIYEFTGIIKRKR"
     gene            36060..37160
                     /gene="glf"
                     /locus_tag="VV588_000865"
     CDS             36060..37160
                     /gene="glf"
                     /locus_tag="VV588_000865"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEU7083236.1"
                     /translation="MYDYLIVGAGLSGAIFAHEATKRGKKVKVIDKRDHIGGNIYCEN
                     VEGINVHKYGAHIFHTSNKKVWDYVNQFAEFNNYINSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKIAEQTAGMKDVEPKNLEEQAIKLIGPDIYEKLIKGYTEKQWGRSA
                     IELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASANKVVFTGMIDQYFDYKHGELEYRSLRFEHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGMQPKTVITHEYPADWKRGDEPYYPINDEKNNAMFAKYQEEAAQNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFSN"
     gene            37187..38056
                     /gene="rfbA"
                     /locus_tag="VV588_000866"
     CDS             37187..38056
                     /gene="rfbA"
                     /locus_tag="VV588_000866"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU7083237.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLTLAQPLKKN
                     EYGQYLLRLIGEA"
     gene            38057..38650
                     /locus_tag="VV588_000867"
     CDS             38057..38650
                     /locus_tag="VV588_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU7083238.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDL"
     gene            38663..39712
                     /gene="rfbB"
                     /locus_tag="VV588_000868"
     CDS             38663..39712
                     /gene="rfbB"
                     /locus_tag="VV588_000868"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU7083239.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            39778..40629
                     /gene="rfbD"
                     /locus_tag="VV588_000869"
     CDS             39778..40629
                     /gene="rfbD"
                     /locus_tag="VV588_000869"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU7083240.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            40692..41162
                     /locus_tag="VV588_000870"
     CDS             40692..41162
                     /locus_tag="VV588_000870"
                     /inference="COORDINATES: protein motif:HMM:NF013739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HEU7083241.1"
                     /translation="MYDYLVVGAVFAHEAALEGKKVKVIEKRNHIAGNIYTREEEGIQ
                     VHQYGAHIFHTSDKEIWDYVNQFAEFNRYTNSPVANYKGEIYNLPFNMNTFNKLWGVV
                     TPAEVQAKIDEQRAILNGKTPENLEEQAISLVGTDIYEKLIKDYTEKQWGQTNY"
     gene            41128..41304
                     /locus_tag="VV588_000871"
     CDS             41128..41304
                     /locus_tag="VV588_000871"
                     /inference="COORDINATES: protein motif:HMM:NF015247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083242.1"
                     /translation="MQRNSGGKPTTELPSFIIRCLPVHLTYDNNYFNDTYQGIPIGGY
                     TQIVEKCWIMKILM"
     gene            41280..41865
                     /locus_tag="VV588_000872"
                     /pseudo
     CDS             41280..41865
                     /locus_tag="VV588_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT        13207 a         6979 c         9108 g        12679 t
ORIGIN      
        1 atgaaagcgc taatattttt ttaaaaaaac tattgacaag ataaaaataa aggattacaa
       61 tggggaatat aaagtaaacc ggtaaaccta aacaagaaag gagaaaagat gaaaattgta
      121 cttgtagggc atggacattt tgctacaggg atttatagtt ctttacaatt gattgcaggt
      181 aatcaagaaa atgtggaggc gattgacttt gtggaaggaa tgtcagcaga tgaactcaag
      241 caaaaaatct tacttgcaat ttcaaatgaa gaagaagttt taatcctaag tgatctcttg
      301 ggaggatcgc cattcaaggt ttcttctacc ataatgggag aaaatccagc caaaacaatg
      361 aatgttctct cgggtttgaa cttagccatg ttaatggaag cagtttttgc tagaatggct
      421 catagctttg atgaggttgt taataaatca gtagtggcgg cccagggcgg agtcgtaaat
      481 ggtaaagaat tgttttcaac ggatgcagag gaagaggaag aagatttcga atcgggtatt
      541 taaagggtga aagaatgata aaaaaggtta cgattgaaga aataaaatcg cctgagcgct
      601 tcttagaagt accacttctg acgaaagaag aagtcggcca ggcaatcgat aaggttattc
      661 ggcagttaga actcaacctt gactatttca aggaagattt cccgacgcca gctacctttg
      721 ataatgtcta tccaatcatg gataacacgg aatggaccaa tggtttctgg acaggagaac
      781 tgtggttggc ttatgaatac agtcaacagg atgcatttaa aaacatcgct cataaaaatg
      841 ttctttcttt cctggatcgt gtcaataaga gagtagaatt ggctcaccat gatctcggct
      901 tcttgtacac accgtcttgt atggctgaat ataagataaa tggagatgga gaggctagag
      961 aagcagcctt gaaagctgca gataagttga ttgaacgcta tcaagaaaaa ggtggtttta
     1021 ttcaagcttg gggagacttg ggcaagaaag agcattaccg tttgattatc gattgcttgc
     1081 tcaatatcca actcttattc tttgcttatc aagaaacagg cgatcaaaaa tactacgata
     1141 ttgcagaaag ccatttctat gcttcagcta ataatgtaat ccgtgatgac gcttcgtcct
     1201 tccacacctt ctattttgat cctgagacag gtcaaccctt taaaggtgta acgagacaag
     1261 ggtatagtga tgattcatgc tgggcacgtg gtcagtcatg gggagtttat ggtattcctt
     1321 tgacttatcg tcacttaaaa gacgagtcct gctttgactt gtttaagggt gtgaccaatt
     1381 atttcttgaa tcgtctgcca aaagatcatg tgtcctattg ggatttgatt tttaatgatg
     1441 gtagtgatca atcacgagat tcttcagcaa cagctatcgc cgtctgtggg attcatgaaa
     1501 tgctaaaaca tctcccagag gtggatgctg acaaagatat ttataaacat gctatgcatg
     1561 ccatgcttcg ttccttgatc gaacattatg caaatgatca atttacccct ggtgggacaa
     1621 gtctcctcca cggtgtgtac tcatggcatt caggtaaagg agtggatgaa ggcaatatct
     1681 ggggtgacta ctattaccta gaagccctta tccgtttcta caaagactgg aacctatatt
     1741 ggtaggagga gaaatatgac aatgccaaat attattatga cccgtatcga tgaacggttg
     1801 attcatggac aaggacaact ttgggtaaaa tacctaggtt gtaatacggt cattgttgcc
     1861 aatgacgaag taagcacgga caagatgcaa caaactctga tgaaaacagt tgtgccagac
     1921 tcagttgcca tgcgtttctt ccctttgcaa aaggtgattg atatcattca caaggctaat
     1981 cctgctcaaa cgatctttat cgttgtaaag aatgtgaagg atgctttaac cttggtagaa
     2041 ggtggtgtcc ctatcaaaga aatcaatatt gggaacattc acaatgctac tggtaaagag
     2101 caagtgacac gctccatctt cctgggtgaa gaggacaagg cggccctcaa ggaattgagc
     2161 caaactcatc aagtaacatt taatacgaaa acaactccaa caggaaatga tggagctgtt
     2221 caagtcaaca ttatggacta tatttaaaag aggagatcgt tatgtcgatt aatgtatttc
     2281 aagcgatttt aattggatta tggacagctt tctgttttag tggaatgctg ttaggaattt
     2341 acaccaatag atgcattgtt ctgtcatttg gtgtcggaat tattctaggt gatctgccta
     2401 ctgctcttgc aatgggagct attggtgaat tggcttatat gggattcggt gttggtgctg
     2461 gaggtactgt tccaccaaac ccaatcggac ctggtatctt tggtaccttg atggctatca
     2521 ctagtgctgg taaagtcagt ccagaagcgg ctcttgccct ctctactccg attgctgtgg
     2581 cgattcaatt cttacaaact ttcgcctaca ctgtacgtgc tggtgcgcct gaaacagcga
     2641 tgaagcactt gaaaaaccat aatttgaaga aatttaagtt cactctaaat gcaacaattt
     2701 ggttgtttgc ctttattgga tttaccttgg gttgcttggg tgccctttca atggatacct
     2761 tgttgaaact cgtagactac attccaccgg tattgcttac aggtttgaca gttgctggta
     2821 aaatgctccc agctatcggt tttgcgatga tcttgtcagt gatggctaag aaagagttga
     2881 ttccctttgt cttgttggga tatgtttgtg cagcttatct aaacatccca acaattggta
     2941 ttgcaattgt aggtactatc tttgctttga ttgaatttta taacaagcca aaaacagcgg
     3001 atcatgtggt agaggaggaa gcacacgatg actggatcta acaaattaac aaaacgtgat
     3061 tatcttaaaa cgtctttgcg ggcattcttt tgtcaaaatg gatttaacta tagtaactat
     3121 caagggttgg gatatgccaa tgtgatgtat cctgctttga aaaaacacta tggagaggat
     3181 caggaaggtt tctaccaagc cttggaagaa aactgtgaat tctataatac caacccacac
     3241 ttcctgcctt ttattaccag cttgcatctt gtaatgttgg aaaatggccg tccggcaaaa
     3301 gaaacacgta gcatcaagat ggccttgatg ggaccattgg caggtattgg ggattctctt
     3361 tctcaattct gtttagctcc attgttctca accatcgcag cttcgtttgc tcaagaaggc
     3421 ttggttgtcg gtccaatctt gttcttcctt gcgatgaata cgattttaac agcgattaaa
     3481 ttgtcaactg gtctgtatgg atacaaacta ggaacaactg tgattgataa actaagcgaa
     3541 cagatggcaa cgatttctcg tattgccaat attatcggtg taaccgtaat tgctggtttg
     3601 gcagcgacat ctgttaagat tatggtgccg attacctttg ctgcagggga agttaaagca
     3661 gacgctaaac aaagtatcgt aagtattcag ggaatgcttg ataaggttgc tccagctctt
     3721 ctaccagccc tatttacact tttagtttac tacttgatca aagaaaagaa atggacaaca
     3781 tataaactcg ttattttaac agttatcatc ggaattatcg gaagctggct taagattata
     3841 gcttaatgga tacaacattg ttttatggaa tagtgattgt cttggcagtg agtccccttt
     3901 tactgtcaag ctttcattct attcgtcagc aaaagttgct tcgcaaacag atggagcaac
     3961 gacaagagta tttagcttct ttaacatctg gtgatgaagt gttgttattg tctggaattc
     4021 atggaaaaat catttctatc aaagatgact tggtctcctt gcagattgca aaaggtgtgg
     4081 tcatctatgt agaaaaggaa agtgtaatgg gaaagacaaa agaactgctt tttaagtagt
     4141 tctttttctg gtaatagata atgaaagaag aaagaagaca attttttgaa agaatcgatg
     4201 gaaaccaatg tcgtgattat atcttgtccc actgttcaaa agactatgag aaagtcaaga
     4261 gttcccttga acgcttgatg gacaatcgtt ttatgtttga tagtccttgg gatatggagc
     4321 cttgttcaaa aatccatcaa atccagccga tggtatggga tcaagtattt gaagatgatc
     4381 cagaatgggc ttatatgctc aatcgacaag aatatctctt gcagtttatg atagggtatc
     4441 tggtagaagg agataagagc tatattcaaa agtgcaagtt ctttctattt gattggattg
     4501 agcaggtgag agaattttct cctcaatcct tgatgactag aaccttggat acgggtattc
     4561 gttcctttac ttggttgaaa ctactcttgc tcctcttgaa atttgacttg ctagaggaga
     4621 aagaactaga gaaaattttg gtcagtctag aaaagcagat tgactttatg aaaagccact
     4681 atcgcgccaa gtacaccctt agtaactggg ggattttaca aacaattccg atgcttgcta
     4741 tctattattt cttttcagat aagatggatc tagaagaagc ttaccatttt gcttcagagg
     4801 agttgaaaca gcaaattgag acacagattt taggagatgg aagccagttt gaacagtcga
     4861 ttctctatca tgtagaggtt tataaagcct tgctggattt gtgtctcttg cttccagact
     4921 tgcaagatag ttaccgagag ttgctggaaa agatggcgac ctatattcaa atgatgacag
     4981 gcttagatgg acgaactttg gcttttggtg atagcgattc tacagaaacg acagaaattt
     5041 tgagcctgtc tgctgtggtt ttgaacaagg aagaccttct taacggtctg gatgttaaag
     5101 tcgatttgct tagcctcttg ttcctggggc gagaaaaggt caagcgactg caggaatttg
     5161 aaaggagagc ttggcagcct aagtccatga tctttgaaga ctctggacat gtctgcatta
     5221 aggatgaaca tcgttatcta tttttcaaaa atggtccgct aggaagtgcc catagccata
     5281 gtgacgagaa tagtttttgc ttacagtatc aaggccaacc tattttcata gatgctgggc
     5341 gttattctta tcgggagata tatgaacgtt atctcttaaa tagtgcttgg agtcattcga
     5401 cctgcattgt agatgggaaa gctccggaaa gaatcacggg atcctgggaa tatgaatact
     5461 atcctcactc cctgttttgt caccataaag aaagggaggg agtgcattat attgaggggg
     5521 cttattggtc agcagaacct gatttgcctt atcttcacaa gagaaaaatc ctcatgttgg
     5581 tagaggatgt ctggctcttg gtagatgaca tcaggtgtca aggtcagcat gaggcgttga
     5641 ctcagtttat ccttgacaag gatgtgacct atcaagatgg gaaaatcaat cagttgagac
     5701 tatggagtga agttgatttt gatttggaag ataccatcat ttctcctaaa tacaatgagc
     5761 ttgaaagaag tagcaaactc accaagcgcc aattctttga gaatcagatg ctggattata
     5821 ccatcattgc gcatgagagt tttgaaatca tccgtcattc tgtctaccag acagatgatc
     5881 gtgaagtgga aaatgctctg gcttttgaag tgaaaaatga cgaaacagac aagctgattc
     5941 tgttattaag cgaggatatt ggtgtaggtg aaaaattgtg cctcgttgac ggaacaaaaa
     6001 tgcgtggaaa atgtctagta tatgataaaa taaatgagag aatgattcgc ttgcagtgct
     6061 agaaataggc attttgaata gtgaatatgt tataataagt attagtagga ggtgttttag
     6121 attggagaag aaactgacca taaaagacat tgcggaaatg gctcagacct cgaaaacaac
     6181 cgtgtcattt tacctaaacg ggaaatatga aaaaatgtcc caagagacac gtgaaaagat
     6241 tgaaaaagtt attcatgaaa caaattacaa accgagcatt gttgcgcgta gcttaaactc
     6301 caaacgaaca aaattaatcg gtgttttgat cggtgatatt accaacagtt tctcaaacca
     6361 aattgttaag ggaattgagg atatcgccag ccagaatggc taccaggtaa tgataggaaa
     6421 tagtaattac agccaagaga gtgaggaccg gtatattgaa agcatgcttc tcttgggagt
     6481 agacggcttt attattcagc cgacctctaa tttccgaaaa tattctcgta tcatcgatga
     6541 gaaaaagaag aaaatggtct tttttgatag tcagctctat gaacaccgga ctagctgggt
     6601 taaaaccaat aactatgatg ccgtttatga catgacccag tcctgtatcg aaaaaggtta
     6661 tgagcatttt ctcttgatta cagcggatac gagtcgtttg agtactcgga ttgagcgggc
     6721 aagtggtttt gtggatgctt taacagatgc taatatgcgt cacgccagtc taaccattga
     6781 agataagcat acgaatttgg aacaaattaa agaattttta caaaaagaaa tcgatcccga
     6841 tgaaaaaact ctggtattta tccctaactg ttgggcccta cctctagtct ttaccgttat
     6901 caaagagttg aattataact tgccacaagt tgggttgatt ggttttgaca atacggagtg
     6961 gacttgcttt tcttctccaa gtgtttcgac gctggttcag ccctcctttg aggaaggaca
     7021 acaggctaca aagattttga ttgaccagat tgaaggccgc aatcaagaag aaaggcaaca
     7081 agtcttggat tgtagtgtga attggaaaga gtcgactttc taaaatgaag gaaaatgact
     7141 tgcaatctct gttaagaaat aaaataatcc cacctagaac aagctaggtg ggattatttg
     7201 cctatgaaat gagaaattat gggagcaagc tcctaaatca actgtttttg atctacttct
     7261 ttaactactt gataaaagtt atagaagtag gccaaacttg aaatgatggt tacgactagg
     7321 aatattgaaa atttccattg gacagggttg gttaaaagtt gtggaaagga tatgaggaga
     7381 aagaagaggg ctgcgttgag gacaggtatc cgttttgatt gtattttctc aagtccttta
     7441 ttgagcgcag gaagaaagag gagtaggagt agtaaaactg tatgagaaac agctcctgaa
     7501 ataagggcaa agaaaaggaa aatactgata aaaacatgaa tgatcagtag tctagctagt
     7561 gatttcataa ggtacctcct aatcctggtc ttttttagct cttgcaatac gaagtgagtc
     7621 gacaatatgt atcatcactc cgaaaaagaa agctcccagt atagttttaa aaatatgttt
     7681 tgtatttaga agagaactga taaaatttgg attttcactt gttagggtat caatgagtgg
     7741 aattataaaa aatatcactg ttccataaat cgaacctgct ttcagaccag gataacgtaa
     7801 ctgtttcttt tcttttttca tgagtttgct ccttttttaa aaatcttcct cccaaaagag
     7861 actgttgagg tcagtttgga ggctgcgggc gagattgaga cagagttcca aggttggatt
     7921 gtacttgtcg ttttcaatca tattgatagt ctgtctcgag acaccgatat tcttggcgag
     7981 ctcgagctgg gaaatgccca gttccttgcg aaattctttc acacgattca tctgttcttc
     8041 tttctgattt atgtcgtata tatttgacta tattatagtc ttttaaacat aaagtgtcaa
     8101 gtatttttga catatttttt gaagaaatag tagtctcctt gtcctatttg tctgacaagt
     8161 gcaagctggt cggatttgtg gtaaaataga taagatatga caaaagaatt tcatcatgta
     8221 acggtcttac tccacgaaac gattgatatg cttgacgtaa aacctgacgg tatctacgtt
     8281 gatgcgactt tgggtggagc aggccatagc gagtatttat taagtaaatt aagtgaaaaa
     8341 ggccatctct atgcctttga ccaggatcag aatgccattg acaatgcgca aaaacgcttg
     8401 gcaccttaca ttgagaaggg aatggtgacc tttatcaagg ataacttccg tcatttacag
     8461 gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa tttgttatga cttgggagtg
     8521 tctagtcctc aattagacca gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg
     8581 gacatgcgga tgaatcagga tgctagtctg acagcgtatg aagtggtgaa caattatgac
     8641 tatcatgact tggttcgtat tttcttcaag tatggagagg acaaattctc taaacagatt
     8701 gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg agacaacgac tgagttagca
     8761 gagattatca agttggtcaa acctgccaag gaactcaaga agaagggtca tcctgctaag
     8821 cagattttcc aggctattcg aattgaagtc aatgatgaac tgggggcggc agatgagtcc
     8881 atccagcagg ctatggatat gttggctctg gatggtagaa tttcagtgat tacctttcat
     8941 tccttagaag accgcttgac taagcaattg ttcaaggaag cttcaacagt tgaagttcca
     9001 aaaggcttgc ctttcatccc agatgatcgc aagcccaaga tggaattggt gtcccgtaag
     9061 ccaatcttgc caagtgcgga agagttagaa gccaataacc gctcgcactc agccaagttg
     9121 cgcgtggtca gaaaaattca caagtaagag ggaaaaagat ggcagaaaaa atggaaaaaa
     9181 caggtcaaat actacagatg caacttaaac ggttttcgcg tgtggaaaaa gctttttact
     9241 tttccattgc tgtaaccact cttattgtag ccattagtat tatttttatg cagaccaagc
     9301 tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca gatagaggaa aagaagaccg
     9361 aattggacga tgccaagcaa gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa
     9421 ttgccaattc acacgatttg caattaaaca atgaaaatat tagaatagcg gagtaagata
     9481 tgaagtggac aaaaagagta atccgttatg cgaccaaaaa tcggaaatcg ccggctgaaa
     9541 acagacgcag agttggaaaa agtctgagtt tattatctgt ctttgttttt gccatttttt
     9601 tagtcaattt tgcggtcatt attgggacag gcactcgctt tggaacagat ttagcgaagg
     9661 aagctaagaa ggttcatcaa accacccgta cagttcctgc caaacgtggg actatttatg
     9721 accgaaatgg agtcccgatt gctgaggatg caacctccta taatgtctat gcggtcattg
     9781 atgagaacta taagtcagca acgggtaaga ttctttacgt agaaaaaaca caatttaaca
     9841 aggttgcaga ggtctttcat aagtatctgg acatggaaga atcctatgta agagagcaac
     9901 tctcgcaacc taatctcaag caagtttcct ttggagcaaa gggaaatggg attacctatg
     9961 ccaatatgat gtctatcaaa aaagaattgg aagctgcaga ggtcaagggg attgatttta
    10021 caaccagtcc caatcgtagt tacccaaacg gacaatttgc ttctagtttt atcggcctag
    10081 ctcagctcca tgaaaatgaa gatggaagca agagcttgct gggaacctct ggaatggaga
    10141 gttccttgaa cagtattctt gcagggacag acggcattat tacctatgaa aaggatcgtc
    10201 tgggtaatat tgtacccgga acagaacaag tttcccaacg aacgatggac ggtaaggatg
    10261 tttatacaac catttccagc cccctccagt cctttatgga aacccagatg gatgcttttc
    10321 aagagaaggt aaaaggaaag tacatgacag cgactttggt cagtgctaaa acaggggaaa
    10381 ttctggcaac aacgcaacga ccgacctttg atgcagatac aaaagaaggc attacagagg
    10441 actttgtttg gcgtgatatc ctttaccaaa gtaactatga gccaggttcc actatgaaag
    10501 tgatgatgtt ggctgctgct attgataata atacctttcc aggaggagaa gtctttaata
    10561 gtagtgagtt aaaaattgca gatgccacga ttcgagattg ggacgttaat gaaggattga
    10621 ctggtggcag aatgatgact ttttctcaag gttttgcaca ctcaagtaac gttgggatga
    10681 ccctccttga gcaaaagatg ggagatgcta cctggcttga ttatcttaat cgttttaaat
    10741 ttggtgttcc gacccgtttc ggtttgacgg atgagtatgc tggtcagctt cctgcggata
    10801 atattgtcaa cattgcgcaa agctcatttg gacaagggat ttcagtgacc cagacgcaaa
    10861 tgattcgtgc ctttacagct attgctaatg acggtgtcat gctggagcct aaatttatta
    10921 gtgccattta tgatccaaat gatcaaactg ctcggaaatc tcaaaaagaa attgtgggaa
    10981 atcctgtttc taaagatgca gctagtctaa ctcggactaa catggttttg gtagggacgg
    11041 atccggttta tggaaccatg tataaccaca gcacaggcaa gccaactgta actgttcctg
    11101 ggcaaaatgt agccctcaag tctggtacgg ctcagattgc tgacgagaaa aatggtggtt
    11161 atctagtcgg gttaaccgac tatattttct cggctgtatc gatgagtccg gctgaaaatc
    11221 ctgattttat cttgtatgtg acggtccaac aacctgaaca ttattcaggt attcagttgg
    11281 gagaatttgc caatcctatc ttggagcggg cttcagctat gaaagactct ctcaatcttc
    11341 aaacaacagc taaggctttg gagcaagtaa gtcaacaaag tccttatcct atgcccagtg
    11401 tcaaggatat ttcacctggt gatttagcag aagaattgcg tcgcaatctt gtacaaccca
    11461 tcgttgtggg aacaggaacg aagattaaaa acagttctgc tgaagaaggg aagaatcttg
    11521 ccccgaacca gcaagtcctt atcttatctg ataaagcaga ggaggttcca gatatgtatg
    11581 gttggacaaa ggagactgct gagacccttg ctaagtggct caatatagaa cttgaatttc
    11641 aaggctcggg ctctactgtg cagaagcaag atgttcgtgc taacacagct atcaaggaca
    11701 ttaaaaaaat tacattaact ttaggagact aatatgttta tttccatcag tgctggaatt
    11761 gtgacatttt tactaacttt agtaggaatt ccggccttta tccaatttta tagaaaggcg
    11821 caaattacag gccagcagat gcatgaggat gtcaaacagc atcaggcaaa agctgggact
    11881 cctacaatgg gaggtttggt tttcttgatt acttctgttt tggttgcttt ctttttcgcc
    11941 ctatttagta gccaattcag caataatgtg ggaatgattt tgttcatctt ggtcttgtat
    12001 ggcttggtcg gatttttaga tgactttctc aaggtctttc gtaaaatcaa tgaggggctt
    12061 aatcctaagc aaaaattagc tcttcagctt ctaggtggag ttatcttcta tcttttctat
    12121 gagcgcggtg gcgatatcct gtctgtcttt ggttatccag ttcatttggg atttttctat
    12181 attttcttcg ctcttttctg gctagtcggt ttttcaaacg cagtaaactt gacagacggt
    12241 gttgacggtt tagctagtat ttccgttgtg attagtttgt ttgcctatgg agttattgcc
    12301 tatgtgcaag gtcagatgga tattcttcta gtgattcttg ccatgattgg tggtttgctc
    12361 ggtttcttca tctttaacca taagcctgcc aaggtcttta tgggtgatgt gggaagtttg
    12421 gccctaggtg ggatgctggc agctatctct atggctctcc accaggaatg gactctcttg
    12481 attatcggaa ttgtgtatgt ttttgaaaca acttctgtta tgatgcaagt cagttatttc
    12541 aaactgacag gtggtaaacg tattttccgt atgacgcctg tacatcacca ttttgagctt
    12601 gggggattgt ctggtaaagg aaatccttgg agcgagtgga aggttgactt cttcttttgg
    12661 ggagttgggc ttctagcaag tctcctgacc ctcgcaattt tgtatttgat gtaagaatgg
    12721 caccctgatg tttcagggtg tttttgtgtt taaatacaca atgaaaatca aagaacaaac
    12781 tagaaagcta actttaggct gctcaaaata taatatattg aaactagaat agtacacctc
    12841 tacttctaaa acattgttag aaatcgattt gactgtcctg aacgatttat cctgttctta
    12901 tttcatttta ctatacagtt tcgaggttgt agataaggcg aagctgatgt ggtttgaaga
    12961 gattttcgaa gagataaaaa atattggtca attaaagtca aaatccttga ccttttctga
    13021 ctaatgtagt atattatgaa cgtaaggtaa atgaaagcct tactagaaca cttatttaaa
    13081 gtaaaataga aagaggtggg gtctatgttt aatctagaaa tcttcagaag taaagatggt
    13141 ctactcctgc ttgaaaaaga aaaaccagaa atagtacgta gggtagcggt ttagctagtc
    13201 taaatttttt aaaacaaagg tcaaagatag tcaatatcag taatcataac taagtaaaca
    13261 aaaagaggta aagaatatga ataacaactt taataatttt aataacatgg atgatttatt
    13321 taaccaattg atgggtggta tgcgaggata cagttctgaa aatcgccgtt acttaattaa
    13381 tgggcgcgaa gtcacacctg aggaatttgc tcactatcgt acgactggtc aattaccagg
    13441 aaatgcagaa actgatgtgc aaatgtcaca acaggcatca ggtatgaaac aagacggtgt
    13501 ccttgcaaaa ctaggtcgaa acttgacagc agaagcgcgt gagggtaagt tggatcctgt
    13561 tatcggacga aacaaggaaa ttcaagaaac atctgaaatc ctctcacgcc gcaccaagaa
    13621 caatcctgtt ttggtcggag atgcaggtgt tggtaagaca gcagttgtcg aaggtctagc
    13681 gcaagccatt gtgaacggag atgttcctgc tgctatcaag aacaaggaaa ttatttctat
    13741 tgatatctca ggtcttgagg ctggtactca ataccgtggt agctttgaag aaaatgtcca
    13801 aaacttagtc aatgaagtga aagaagcagg gaatattatc ctcttctttg atgaaattca
    13861 ccaaattctt ggtgctggta gcactggtgg agacagtggt tctaaaggac ttgcggatat
    13921 tctcaagcca gctctctctc gtggagaatt gacagtgatt ggggcaacaa ctcaagacga
    13981 ataccgtaac accatcttga agaatgctgc tcttgctcgt cgtttcaacg aagtgaaggt
    14041 caatgctcct tcagcagaga atacttttaa cattcttcaa ggcattcgtg acctctatca
    14101 acaacatcac aatgtcatct tgccagacga agtcttgaaa gcagcggtgg attattctgt
    14161 tcaatacatt cctcaacgta gcttgccaga taaggctatt gaccttgtcg atgtaacagc
    14221 tgctcacttg gcggctcaac atccagtaac agatgtgcat gctgttgaac gagaaatcga
    14281 aacggaaaaa gacaagcaag aaaaagcagt tgaagcagaa gattttgaag cagctctaaa
    14341 ctataaaaca cgcattgcag aattggaaaa gaaaatcgaa aaccacacag aagatatgaa
    14401 agtgactgca agtgtcaacg atgtggctga atctgtggaa cgaatgacag gtatcccagt
    14461 atcgcaaatg ggagcttcag atatcgaacg tttgaaagat atggctcatc gcttgcaaga
    14521 caaggtgatt ggtcaagata aggccgtaga agttgtagct cgtgctatcc gtcgtaaccg
    14581 tgctggtttt gatgaaggaa atcgcccaat cggcaacttc ctctttgtag ggtctactgg
    14641 ggttggtaag acggagcttg ctaagcaatt ggcactcgat atgtttggaa cccaggatgc
    14701 gattatccgt ttggatatgt ctgaatacag tgaccgcaca gctgtttcta agctaattgg
    14761 tacaacagca ggctatgtgg gttatgatga caatagcaat accttaacag aacgtgttcg
    14821 tcgcaatcca tactctatca ttctcttgga tgaaattgaa aaggctgacc ctcaagttat
    14881 tacccttctc ctccaagttc tagatgatgg tcgtttgaca gatggtcaag gaaatacagt
    14941 aaacttcaag aacactgtca ttattgcgac ctcaaatgct ggatttggct atgaagccaa
    15001 cttgacagaa gatgcggata aaccagaatt gatggaccgt ttgaaaccct tcttccgtcc
    15061 agaattcctc aaccgcttta atgcagtcat cgagttctca cacttgacta aggaagacct
    15121 ttctaagatt gtagatttga tgttggctga agttaaccaa accttggcta agaaagacat
    15181 tgacttggta gtcagtcaag cggctaaaga ttatatcaca gaagaaggtt acgacgaagt
    15241 catgggggtt cgtcctctcc gtcgagtggt tgaacaagaa attcgtgata aggtgacaga
    15301 cttccactta gatcatttag atgctaaaca tctggaagca gatatggaag atggcgtttt
    15361 ggttattcgt gagaaagcct aagatagaat tttgaggata aaaaagaagg agccagctga
    15421 aaaaaactgg ttccttttga ggtacgacgg gcatgtcgta cagtagaagt gtactattct
    15481 agtttcaatc cactatagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag
    15541 tccttgaaaa acgtggattg gtttcgtgtt tggattatta ccttgaacga catgcgttaa
    15601 aagttagttg aaccgccgta tgccgaacgg cacgtacggt ggtgtgagag gggctagaga
    15661 ttatccccta ctcgatttta aatcacatga cgttcaaagg catcatctga aatcccttgt
    15721 tccaagatga gttttgccca ttctttagca gagaagaggc tgtggtcctt gtagtttccg
    15781 caagattcga tggttgtccc tgggacatct tcccaagtag tagtttcagc gatttccttg
    15841 agcgaatcct tgataacagc tgcgatttta gcactggtgt gacgtcccca cataatcatg
    15901 tggaagcctg tgcggcaacc aaatggtgaa cagtcaatca tgccgtcaat gcgggtacgg
    15961 atgagtttgg ctaagaggtg ctcgatagtg tgaaggccgg cagtagggat agagtcttcg
    16021 tttggttgca ccaagcgaat atcataattg gagatgatgt ctccttttgg tcctgtttct
    16081 tccccaatca agcgaacata gggtgctttg acaatggtgt ggtcaagttc aaaactttcg
    16141 acaataactt cttttgacat ggtaaatcct ttcagttttc ttctctcatt atatcataaa
    16201 ggttgttcct gagacagaga gaaaacctct ccgaggctag agaggttgaa atctttactt
    16261 acgatataag cggtcgtatt ggtagtatgg gtcaaaggtt acgttgatac ccagtttacg
    16321 aaggacattc ttgtcttcat cagtcaagat gatggttgag tgggcttcgc ttcctttgag
    16381 gttgcctagt tcttccatag cgcgggcagc atcaggattt tctgtagctg tgatagcaag
    16441 tgcaatcagg atttcatttg aatgaaggcg tggattgcgg ctaccgagat gatcgatttt
    16501 aagaccttgg attggcttaa caacttcagg ttcgattagt tttacttctt tagcgatgtc
    16561 agctgatttt ttgatggcgt tgatcaaggc agcggctgta ggaccaaaga gttctgagtt
    16621 cttaccagtg acgatttccc catttggcaa ttcaaaggct agggctggtc caccagtttc
    16681 ttctgctttt tggcgcgcaa cgacagcaac cttacggtct gcaggtgtga taccgaggtc
    16741 gttcatgagc aactcaattt tcttgacggc agcttcgcca actttttcag ctttgaagtc
    16801 aagaactgtt tgatagtaac ggcggatgat ttcttgttta gaagcttcga cagcggcctc
    16861 gtcatctgta atagcgaaac caaccatgtt gacacccata tctgtcggtg aagcgtatgg
    16921 tgattttccg agaatacgtt ccgacatgcg tttgagcact gggaagattt cgatatcacg
    16981 gttgtagttg acagtggttt ctccataggt ttgaagatgg aaggggtcaa tcatgttgac
    17041 atcatcaagg tcagctgtgg cagcttcata agccaagtta actggatgat gaaggggaag
    17101 attccaaaca gggaaggttt caaatttagc gtagccagat ttgatgccat tgatttggtc
    17161 gtggtacata ttggacatac acgttgccaa ttttccagaa ccgggtccag gagcggttac
    17221 gacaatcaag ttgcgactgg ttttgatgta gtcgtttttg cccatgcctc ctggggaaat
    17281 gatgtgatcc atatccgtag gatatccttt gattggataa tgaagataag aatcaattcc
    17341 gtttttctca agttggttgc ggaaggcatc tgcagcgggt tggccagcgt attgtgtaat
    17401 gacaacggaa ccaacaaaaa tccctaattc attgaatttg tcaatcaaac gaagaacttc
    17461 ttggtcataa gaaatgccta agtcgccacg tgctttggaa tgttcaatgt tgctagcatt
    17521 aatggcaatc acaacctcaa cctgctcttt caattcttgc aagagcttga ttttgttgtc
    17581 aggttcataa ccaggaagga cacgagcagc gtggaaatct tctaacattt taccgccaaa
    17641 ctctaagtag agcttgccgt caaattggtt aatgcgctcc aaaatatggt cgcgttgtaa
    17701 attcaaatac tgttcagaac taaaagcttg ttttttcatt tttttacctc tggactctat
    17761 tataataaaa aattggaagt taggaaacta cggagctaaa aaagaaatta aaaagattaa
    17821 gtaaacgctt gcacaaaatt ttaaaaagtg ctatcataga ctatagatta ttaaaataat
    17881 gaggtaaaca gatgcaagaa aaatggtggc ataatgccgt agtctatcaa gtctatccaa
    17941 agagttttat ggatagtaat ggagatggag ttggtgattt gccaggtatt accagtaagt
    18001 tggactatct agctaagtta ggaatcacag cgatttggct ttctcccgtt tatgacagcc
    18061 ctatggatga taatggctac gatattgctg attatcaagc gattgcggct atttttggaa
    18121 ccatggagga catggatcag ctgattgcag aagctaagaa gcgtgatatc cgtatcatca
    18181 tggacttggt ggtcaatcat acctcggatg agcatgcttg gtttgtcgaa gcctgtgaaa
    18241 atactgacag ccctgagcga gactactata tctggcgcga tgaacccaat gacctagatt
    18301 ctatctttag tgggtctgct tgggaatacg atgaaaagtc aggtcaatac tatctccact
    18361 ttttcagcaa gaaacagccg gatctcaact gggaaaatga aaaacttcgc cagaaaattt
    18421 atgagatgat gaacttctgg attgataaag gtattggtgg tttccgtatg gatgttattg
    18481 acatgattgg caaaattcct gacgagaagg tagtcaataa tggtcctatg ctccatccct
    18541 atctcaagga aatgaatcag gcgacctttg gagataagga gctcttgaca gtaggggaga
    18601 cttggggagc aacgccagag attgccaagc tctactctga tccaaagggg caagaattgt
    18661 ctatggtctt ccagtttgaa catatcggtc ttcagtatca ggaaggtcag cctaaatggc
    18721 actatcaaaa agagctgaat atcgctaagt taaaagaaat cttcaacaaa tggcagacag
    18781 agttaggagt tgaggacggc tggaattccc tcttctggaa caaccatgac ctccctcgta
    18841 ttgtctcaat ctggggaaat gaccaagaat accgcgaaaa atctgccaaa gcctttgcaa
    18901 tcttacttca tctcatgaga ggaactcctt atatctacca aggtgaggag attgggatga
    18961 ccaactatcc gtttgaaaca ctggatcaag tagaagatat tgaatccctc aactatgcgc
    19021 gtgaggctct tgaaaaaggt gttccgattg aagaaatcat ggacagtatc cgtgttattg
    19081 gacgtgacaa tgcccgtacc cctatgcaat gggacgagag caaaaacgct ggtttctcaa
    19141 caggtcaacc ttggttggcg gttaatccaa attacgagat gatcaacgtc caagaagcgc
    19201 tggcaaatcc agattctatt ttctatacct atcagaaact ggtccaaatt cgcaaggaga
    19261 atagctggct aattcgagct gactttgaat tgcttgatac ggctgataag gtctttgctt
    19321 atatacgtaa ggatggcgac cgtcgcttcc tagttgtggc taacttgtct aatgaagagc
    19381 aagacttgac agtagaagga aaagtcaaat ctgtcttgat tgaaaacacc ctagctcaag
    19441 aagtctttga aaaacaaatc ttagttccat gggatgcttt ctgtgtggaa ttactataaa
    19501 tattttttgc agaaaaattt aaaattgaaa tcgtataaaa acaagggagg actgtataaa
    19561 aggcagaaat cctttgtttt ttataaccaa ggtttataaa ccttcattct cgaaattcaa
    19621 ttaactttac aaattcccac tattaaggag aaagaagacg aacataaaga agcgtatcct
    19681 tagtgcaggc ctgactttta catctgattt gcttttagct gcttgcggcc aatcaggttc
    19741 agatacaaaa acttactcat caacctttag tggaaatcca actacattta actatctatt
    19801 agactattac gctgataata tagtcaattg aaacaagaac aggacaaaag agcctcataa
    19861 aaggtattgc aacttggtaa tacctttttg aggtgctttt tgatatgagc ccatgttttc
    19921 tcaataggat tgtactcagg cgagtaggga ggaagaggta aaagtttatg cccaaactct
    19981 tcacacaaga gttctagctt ccccattcta tggaatcttg cattatccat aataataacc
    20041 gatggtgtgg ttaatgttgg taagagaaac ttctgaaacc aagcttcaaa aaagtcgctc
    20101 gtcatcatct cttcgtaagt cattggagcg attaactcac cattcatttg ttagacctgc
    20161 aaccaaagaa atcctctgat atcttcttcc agatacttta cctcttctta actgaccttt
    20221 taatgagcga ccatattctc gatgaaaata agtatcgaat cctgtttcat caatctaaac
    20281 aggtgctagg tgctttaaac tattaaaatt cttaagaaat aaggctactt tttctgggtc
    20341 ttgttcatag taggtgtggt tctttttttc gagtgtagcc catagctttg agcgcatagt
    20401 ggatggtagt tggatgacag gcaaattcag aagctatttc agtcaaataa gcgtctggat
    20461 tattagtaag atagttttta agtctatctc tatcaacttt tcttggtttt gttcctttta
    20521 cttggtggtt tagctctcct gttttctctt ttagctttaa ccagccataa atggtattac
    20581 gtgagatttg gaaaacgtgt gatgcttctg ttatactacc tgttcgctca caataagaga
    20641 gaactttttt acgaaaatct attgaatatg ccataaaaag attataccac attgtgtact
    20701 atattatatt gaaactagaa tagtacacat ctgcttctaa aatattgtta gaaaacgatt
    20761 tgactgtcct gatcaatttg tcatgttctt atttcatttt actatatttt tggttcgcgg
    20821 gaagtctact aagatactta aagatgcaga tagtgaaaat aaaggtgtag acattaccgt
    20881 aaaaaagtga tataatcgta tgatgttcaa tgtataggtg ttaatcatga gtagacgttt
    20941 taaaaaatca agttcacaga aagtgaagcg aagtgttaat atagttttgc tgactattta
    21001 tttattgtta gtttgttttt tattattctt aatctttaag tacaatatcc ttgcttttag
    21061 atatcttaat ctagtggtaa ctgcgttagt cctactagtt gccttggtag ggctactctt
    21121 gattatctat aaaaaagctg aaaaatttac tatttttctg ttggtgttct ctatccttgt
    21181 cagctctgtg tcgctctttg cagtacagca gtttgttgga ctgaccaatc gtttaaatgc
    21241 gacttctaat tactcagaat attcaatcag tgtcgctgtt ttagcagata gtgagatcga
    21301 aaatgttacg caactgacga gtgtgacagc accgactggg actgataatg aaaatattca
    21361 aaaactacta gctgatatca agtcaagtca gaataccgat ttgacgatcg accagagttc
    21421 gtcttacttg gcagcttata agagtttgat tgcaggggag actaaggcca ttgtcttaaa
    21481 tagtgtcttt gaaaatatca tcgagtcaga gtatccagac tatgcatcga agataaaaaa
    21541 gatttatacc aagggattca ctaaaaaagt agaagctcct aagacgtcta agaatcagtc
    21601 tttcaatatc tatgttagtg gaattgacac ctatggccct attagttcgg tgtcgcgatc
    21661 agatgtcaat atcctgatga ctgtcaatcg agataccaag aaaatcctct tgaccacaac
    21721 gccacgtgat gcctatgtac caatcgcaga tggtggaaat aatcaaaaag ataaattaac
    21781 ccatgcgggc atttatggag ttgattcgtc cattcacacc ttagaaaatc tctatggagt
    21841 ggatatcaat tactatgtgc gattgaactt cacttctttc ttgaaaatga ttgacttatt
    21901 gggaggggta gatgttcata atgatcaaga gttttcagct ctacatggga agttccattt
    21961 cccagtaggg aatgtccatc tagactctga gcaggctcta ggttttgtac gtgaacgcta
    22021 ctcactagcc gatggagacc gtgaccgtgg tcgcaaccaa caaaaggtga ttgtggctat
    22081 ccttcaaaaa ttaacgtcaa ccgaagcact gaaaaattat agtacgatca ttaatagctt
    22141 gcaagattct atccaaacaa atatgccact tgagactatg ataaatttgg tcaatgctca
    22201 gttagaaagt ggagggaatt ataaagtaaa ttctcaagat ttaaaaggga caggtcggac
    22261 ggatcttcct tcttatgcaa tgccagacag taacctctat gtgttggaaa tagatgatag
    22321 tagtttagct gtagttaaag cagctataca ggatgtgatg gagggtagat gaaatgatag
    22381 acatccattc gcatatcgtt tttgatgtag atgacggtcc caagtcaaga gaggaaagca
    22441 aggctctctt ggcagaatcc tacaggcaag gggtacgaat cattgtctct acctctcacc
    22501 gtcgcaaggg catgtttgaa actccggaag agaagatagc agaaaacttt cttcaggttc
    22561 gggaaatagc taaggaagtg gcgagtgact tggtcattgc ttacggagct gaaatttact
    22621 acacaccaga tgttctggat aagctggaaa aaaagcggat tccgaccctc aatgatagtc
    22681 gttatgcctt gatagagttt agtatgaaca ctccttatcg cgatattcat agcgccttga
    22741 gcaagatctt gatgttggga attactccag tcattgccca cattgagcgc tatgatgctc
    22801 ttgaaaataa tgaaaaacgc gttcgagaac tgatcgatat gggctgttac acgcaagtaa
    22861 atagttcaca tgtcctcaaa cccaaacttt ttggcgaacg ttataaattc atgaaaaaaa
    22921 gagctcagta ttttttagag caggatttgg ttcatgtcat tgcaagtgat atgcacaatc
    22981 tagacggtag acctcctcat atggcagaag catatgacct tgttacccaa aaatacggag
    23041 aagcgaaggc tcaggaactt tttatagaca atcctcgaaa aattgtaatg gatcaactaa
    23101 tttaggagaa atgatgaaag aacaaaacac gatagaaatc gatgtatttc aattatttaa
    23161 aaccttgtgg aaacgcaagc taatgatttt aatagtggca cttgtgacag gtgcgggggc
    23221 ttttgcatat agcactttta ttgttaagcc agaatatacg agtaccacgc gaatttacgt
    23281 agtgaatcgc gatcaaggag acaagccggg gctgacaaat caggatttgc aggcaggatc
    23341 ttatctggta aaagactacc gtgagattat cctttcgcag aatgtattgg aaaaagtagc
    23401 gacaaatttg aagttggata tgccaacaaa aacgttagcc agcaaagtta aagtgactgt
    23461 accaactgac actcgtatcg tctcaatctc tgtcaaagat aaacaaccag aagaagccag
    23521 tcgtatcgct aattctctac gagaagttgc tgcagaaaag atcgtcgctg taacgcgagt
    23581 atctgatgta acgacacttg aagaagcgcg accagctacg actccctctt ctccaaatgt
    23641 tcgacgcaat tccttgtttg gttttcttgg aggagcagtc gtaacagtaa ttgctgttct
    23701 tttgattgag ttgctcgaca cccgtgtgaa acgtcctgaa gatgtcgaag atgtactgca
    23761 aattccactt ttaggggtcg ttccagattt gaacaaaatg aaataggagg aagttatgcc
    23821 aacattagaa atctcacagg caaaattgga ttttgtaaaa aaggcagagg aatattataa
    23881 cgctttgtgc acgaacctac agttaagtgg agatgatttg aaagtatttt ctatcacttc
    23941 tgtgaaacta ggagaaggaa aatcaacgac ttccaccaat atcgcttggg cttttgcgca
    24001 tgcaggttac aaaacgctgc tgattgatgg agatattcgc aattctgtta tgttaggtgt
    24061 ctttaaagca agggataaga ttacaggcct gacagaattt ttatcaggaa ctacagacct
    24121 atcacaaggg ctttgtgata ccaatgtcga aaatctcttt gtaattcagg ctggctctgt
    24181 gtcaccgaat ccgacagctc ttcttcaaag taagaatttc agtacaatgc ttgaaacctt
    24241 gcgtaaatat tttgactaca tcattgtaga tactgctcct gtcggtgtcg tgattgatgc
    24301 ggctattatt acgcgaaaat gcgatgcttc tattttagtg acggaggtag gtgaaataaa
    24361 tcgacgggat attcaaaaag caaaagaaca gttggaacac acaggaaagc cgtttttggg
    24421 agttgtgttg aataaattcg atacttcagt agacaaatac ggttcttatg gaaattatgg
    24481 agattacggg aaaaataaaa aataggtcgg gggattagag atgaatggaa aaatagtaaa
    24541 gtcttcattg gccataatcc agagttttct tgttatttta ttgacttatc tacttagtgc
    24601 tgtgagagaa gcggagattg tttcaacaac agctattgca ctttatatcc tccattattt
    24661 tgtcttttat atcagtgatt atggacagga tttctttaaa agaggatatt tgattgaact
    24721 tgtccagaca ttgaaatata tcctattctt tgcactagcg attagtattt ctaatttttt
    24781 cttagaggat cgatttagta tttccagacg aggcatgatt tacttcctca cattacatgc
    24841 tctcttagtc tatgtgctaa acctatttat caagtggtat tggaagcggg cttatcccaa
    24901 ctttaaagga agtaagaaga ttctcctact tacagcaact tctcgtgtcg aaaaggtact
    24961 ggatagatta atagaatcaa atgaggttgt tggggagttg gtagccgtca gtgtcttaga
    25021 taaaccagat tttcagcatg attgtttaaa ggtagtagca gagggggaga tagtaaactt
    25081 tgcgactcat gaggtggtcg atgaagtctt tatcaatctt ccaagtgaaa aatacaatat
    25141 tggagagctt gtctctcagt ttgaaacgat gggaattgat gtaacagtta atctaaatgc
    25201 ttttgatcgt agtttggcac gtaacaagca aattcgtgag atggcaggat taaacgttgt
    25261 gactttttct acaacatttt ataagactag tcatgtaatt gctaagcgga ttattgatat
    25321 catgggtgca ttggtagggc tgatactatg tggtttagtc agtattgtac tggttccttt
    25381 gattcgaaag gatgggggct ctgctatttt tgctcagacg cgtataggaa aaaatggtcg
    25441 tcagttcact ttttataagt ttcgctctat gtgtgtagat gccgaggcga aaaaaagaga
    25501 actcatggaa caaaatacca tgcagggtgg aatgtttaag gtggacgatg atcctcgtat
    25561 cacgaaaatt ggttgtttta tacggaagac tagcttggac gagctaccac agttttataa
    25621 tgttctaaag ggagatatga gtttggttgg cacacggcca ccaacagtgg acgagtatga
    25681 gcactatacc ccagaacaaa agcgtcgtct gagttttaaa cctggcataa cagggttatg
    25741 gcaggtcagc ggacgaagtg agattaagaa ttttgatgaa gttgtcaaat tagatgtagc
    25801 ctatatagac gattggacaa tttggaaaga tattgaaatt ttattgaaga cagttaaagt
    25861 tgtattgatg aaggatggag cgaagtgatt tttgcccttc ggtcttgtta ggagagatat
    25921 gaaacagtca gtttatatca ttggttcaaa ggggattcct gccaagtatg gaggatttga
    25981 aacctttgtt gagaaattaa cagaatatca aaaagatggt aacatccaat actatgttgc
    26041 ttgcatgcgc gaaaattctg caaagtcagg atttacagca gacacatttg agtacaacgg
    26101 tgctatttgt tacaacattg atgtgcctaa tattggtcct gctagagcca ttgcttacga
    26161 tattgcagcg gtcaataagg ctattgaatt gtctaaggga aacaaggacg aggctcccat
    26221 tttttacatt ctagcttgtc gtatcggacc ttttatttct ggacttaaga aaaaaattcg
    26281 ttcgatcgga ggccgtttgc tggtaaatcc agatggtcat gagtggcttc gagctaaatg
    26341 gagcttgcca gttcggaagt attggaaatt ttcggaacag ttgatggtca aacatgcaga
    26401 tttattagtc tgcgatagca aaaatatcga aaaatatatt cgagaggact ataaacagta
    26461 tcagcccaag acgacctata tcgcttatgg tacagatact accccttcaa gtctgaaatc
    26521 agaagatgcc aaagttcgaa actggtatcg tgaaaaggga gtaagcgaaa atggctatta
    26581 tctagtggtg ggacgattcg ttcccgaaaa caactatgaa accatgattc gtgaatttat
    26641 caagtctaag tccaataagg actttgtcct tattacaaat gtggaacaga ataaatttta
    26701 cgatcagttg ctcaaggaaa caggtttcga caaggatcta agagtcaaat ttgtgggaac
    26761 agtctatgac caagaattgc tcaagtatat ccgtgaaaat gctttcgcct atttccatgg
    26821 acatgaagtt gggggtacca atccatcgct tcttgaagct ttagcatcca ctaaactcaa
    26881 cttgttgttg gatgtcggct ttaaccgtga agttggtgaa gacggagcca tttattggaa
    26941 aaaagatgag ctagcgcatg taatcgaaga agtggaacga tttgatgaag gtgatattac
    27001 ggaattagac gaaaagtcta gccaacgaat tgcggatgca tttacgtggg aaaagattgt
    27061 gtcagattat gaggaagtgt ttactgtatg aaaattttgc attatacttt aggctttcaa
    27121 ccatcacgta caggtggtct tgtcaagtat gctgaggatt tgatgactca acaagctaca
    27181 gatggacatg aagtaatcgc attatatcca ggagaaatct caattatatt taggcaggtt
    27241 agaataaaaa aagcagagaa tcgaaaattc caatgctata aaataataaa cagcctaccc
    27301 ttggctctat ttggtggtat ttcagaacca gatgaattta tgaagagttg tgataaagct
    27361 tcttatagga aatttttgaa aaatattaag gtagatgtaa ttcacattca ctcgcttata
    27421 ggattacata aggaatttat tgaagttgca aaagaattag gaattaaaac tgtatttaca
    27481 agccatgatt attatggttt agcgccagtt ccgcattttt attttaacgg agtagattat
    27541 agtagtaata atactaattt agcatggaac atcatgtcct ctaatgctct tagtgtaaaa
    27601 aaacttcgat tctttcaagt ctctttttac ccaacaattc ggaaattgat gaaaatgctt
    27661 gggaaaaatc caaagtccaa gaaaaactta gtaattcgtg atatcacgga ggctattgat
    27721 tatagtgctc tccgctctta ttataaagca atgtttgggt taatagatgc ttaccttttc
    27781 aatagtcagt tagctaagga agtttatgaa gctaatcata taatacctaa aaacaatatc
    27841 atagtgtcca tttctaacag ctcaataagt aatcataata ttcgtgttag ttccggtgag
    27901 aaaacagtgg tagcttatat tgggcctgat gaggaatata aggggtattt tgattttcta
    27961 gatatagtta atgatttaga tcaggaaaag tatgatatta aaacatatgg acattttcca
    28021 aatgaagatt gtccacctta tatccaacag aacggttatt tcacaaaaga cacggttgga
    28081 agcgtttatt ccaatataga tattttgatt gtgccgagta ggtggaagga aacatttggt
    28141 ttgattagta tagaggcgct atcgtatgat gtgaatgttt ttgtgagcaa aaatgtgggc
    28201 tctaaagatt tggtttcaga agaacatatc tttcataata aagacgattt gttaaaaaaa
    28261 attcaatatg taaaattcga gaatgtaaaa ttcaaaacga tgaaagagca tatggtggag
    28321 attataaatt actatgaaag gattacaaat gataatcaaa agattaatta agacaattac
    28381 aggtaaagaa attgatcttc accctgatat cccaataact tacattcttc agagaggttt
    28441 tcaatacggt ttgggtctta gtcgagggtt gttacgtggt attggtctag gaaaaaaagg
    28501 caaacgatta tttattggac gtggggtaac ccttctcgca aaacgcaagt tatatgttgg
    28561 aaacaatatc cgaatcggca aatatgtgag catagattgc ctttcaaagg atgggatcca
    28621 aattgcggat aatgttaaga taggagatta ctcgcaaata attggtacag gttcagtaaa
    28681 aaatatgggt attgggctca aaattggaaa gaactcttct ttctcagaat atagtttatt
    28741 cggttctgca ggtgggatta ctatcggagg agatgttatt gctggacaaa atgtacgttt
    28801 tcatgctgag aatcatagct acgaagtgtt gcatatacca atcagagagc aaggtgttaa
    28861 tcgtaaaggg atatccgttg gtgacaattg ctggattggg gcaggagctg tttttttaga
    28921 tggatctagt atcggttcag gttgtatcgt tgcaacgaat gcggttgtta ctaagaaatt
    28981 tccagataat gtaattattg gtggagtgcc agctaaaatt ttaatggaaa gaaagtagta
    29041 ttaaattaat tgtataaatg gagggaaatg atatgtctaa aatgaagatt gctgtagttg
    29101 ggacaggtta tgttggttta tccatttctg tgttacttgc acaacaccat catgtagtag
    29161 cagtagatat tgtaaaagag aaagtagaat taattaataa aagaatttca cctattcagg
    29221 atgattttat tgaaagatat ctttcagaaa gtaatttaga tttagttgca acaatagacg
    29281 ctgaaacagc ttataaagat gcctctttta tcgtagtagc gacaccaaca aattatgact
    29341 tagaaagaaa tttttttgat acatcaacag ttgaatcggt cattcaacaa gttcagaata
    29401 tgaattctac agcaactata gtaataaaat caacagtccc cgtgggcttt accgattcaa
    29461 ttcgtaaaaa attaggaatt tcaaatcttc tattcagtcc tgaatttttg cgtgaatcaa
    29521 gggcacttta tgataactta tatccaagtc ggatcatagt tggaacagat ttaagtaatc
    29581 aaaaattagt tgaaaaagcc caagttttct ctaatctttt agtgcaaggt gccattaaaa
    29641 aagatatccc tattttaact atgggattta ctgaagctga agcagttaaa ttatttgcta
    29701 atacctactt agcattgcgg gtatcatatt ttaatgaatt agatacttat gcagagatca
    29761 aagggttaga tactcaaaaa ataattgaag gtgttagttt agatcctcgt atcggaaccc
    29821 attataataa tccgagcttt gggtatggtg gatattgctt accaaaggat actaagcaac
    29881 ttttagccaa ttataagaat gtcccagaag agcttattgg agctatagta cgaagcaata
    29941 caacacgtaa agattttatt gctaatcaag ttcttaaagt ggtgaattat aatataccag
    30001 aagacgatat tcctactaaa cagatggaga aagaagttgt tattggaata taccgattaa
    30061 ctatgaaaag taacagtgat aactttcgtc agagttcaat acaaggagtt atgaaacgta
    30121 ttaaggatag aggagttaaa gtaatcattt ttgagcctac tctaaaagat agtgatacat
    30181 tctttggaaa cgctgttata aatgatttag aagagttcaa agtaaagtgt gatgtgatta
    30241 ttgcaaatcg ttatgatgaa acgttgaatg acgttaagga taaagtatat acacgagata
    30301 tttttagaag agattgataa aaatatgaaa aaagtattaa ttgttcgaag tggaccttac
    30361 caagtcaatc cggaaggata taatcttcaa gaacttggtt tagcctccgc tatcagtcag
    30421 caaggctacc agtgtgatgt catgtattat cacaaaacaa agaactatga tcaattatat
    30481 gagaaaaatg gggaacaaat taaaatattc tggaggaggg gaataagatt atttagaagt
    30541 ggaatttatc cccagatttt aagagagaaa tttttgaatc agtatgataa gataattatt
    30601 tctgagtaca gccagattat ggcagtttta ttgtctagaa ttcattccaa tgtatatatt
    30661 tataatggcc catactataa tctatttaag attcccatta ttgaacctat atacgatttt
    30721 ctttttgtag aaatgctcaa taagagaacc aaaacagttt tctgcaagac agaaaaagca
    30781 gagtgttatc ttaaaaacaa aggattcaat gattgtaaag tagtgggcgt aggtctagat
    30841 attgagaagt ttgaacaaga agaggaacct acagaggata ctatagagct tttaagaaga
    30901 atggagaata aacaaaatat tctttatgta ggttcactat caaaaagaaa aaacacagct
    30961 cagttaatta gaatttttaa tattttaaaa tctaaaagtg gtaagaaaaa tgaacttcaa
    31021 ttggtattga ttggtaagga tgaggataat attgttgaaa aaattaacta ttcacggttt
    31081 aaagatgata ttatttatca accttattta aagaattctc agcttcaatt tatttaccca
    31141 tcatcacaac tacttgtgct cccgtcagtt caagagattt ttggtatggt attacttgag
    31201 gcaatgtatt ttaagttgcc tgttgtttcc agtgcaagtg ctggaggaga gacactgatt
    31261 caagatggta taaacggtaa aattgtgaat gattttaatg atgaacactg ggtggattgt
    31321 atagaaaatc tattaaataa cccattggaa ttgaaacggc ttggagaatg tgctcataag
    31381 cgcattacgg aacagtttat gtggtcttca attgcgagaa aaataattga gacatttgat
    31441 gaaaggtaag acttgctatg aatttttgtt ttgtgatttt gcattatcgt accagcaatg
    31501 acactataga gtgtatcaaa tcgattcaaa agcttgaggg agattataaa attgtaattg
    31561 ttgataatgc ttctcaaaat ggcagtatag aaagggtaga agccttattt gcaaataatg
    31621 acgagatagt tataataaaa aacacgaaaa acttaggatt tgctgctgga aataatattg
    31681 gatacgccta cgctaggact caaataaaag ctgatatgat tgctgtactt aataatgata
    31741 ttgttattaa gcaaaaagat ttcatcaatc gtatatttga actctataga aattctcagt
    31801 ttcatatcgc tggtccagac attgtctctc ttgtagatgg tcatcatcaa agtcctgttg
    31861 ttgagaagat taattctata tctaaggcta ataaagaact ttttaaatat agaatcttga
    31921 ggattattaa taaaatagga ttatatgagc tgatgactag acagccaaaa aaagaattaa
    31981 atagaataag tgttgcagac cctatgagat atcaggaaaa tgttatttta catgggagtt
    32041 ttgtaatttt ttcaccgttg tatgtttcag aggaggagtg tgctttcaga ccggatacat
    32101 tcatgtatat ggaagagcct attctatatg aatattgcat gcttaaaaat tataagacag
    32161 tatttgatcc ttctattgta atttatcata aagaggactc atcaacaaat tcgttgtata
    32221 atgcagcata tgcaaaaaga gagtttgttt ttaaaaatat gattagatct ctaaagattt
    32281 atagaagtct attgaagtag taaactaagg aaaggataat aattagaaat tgaatcttag
    32341 tatgttagcc ttgacaatag gaacagtggt atttgttaaa aaaacgtata ggacgtttct
    32401 caatcccata attttatttg taattttgtg gtttattata acaactttgt caagtttaaa
    32461 actattccaa cttttcgaga ttagtactca cacacaacaa attattttgc ttgggacttc
    32521 tctatttgtt atagggggag ggatagcaat ttggtttcgg gataaatttt attttaaagt
    32581 tggcggtaac tcatatttta caacagactt tgaaattaat tataatttgt tctttttgct
    32641 aggtatcatt tgccttttct attatttgcc agatttcttt tcctcactgg tatcattaat
    32701 aagaggtggg aatttaaact tagttagaca atctgcgcag gatgcagtag ataccagtgg
    32761 attaaagaat ttcattggaa catttattgt tagtcctagt gccatggtat tagaaatatt
    32821 aggagtatta gatttctgga gcaataaaaa aggtagaaaa ctattttatc ttagtttagc
    32881 tgtcattttt gtaagagtta ttgcagatgc tggtagaaca cctctattta atgttgtcat
    32941 atatttatta cttactgttt tagcaaatag gttctctgaa aaaactgaaa agaagagaaa
    33001 agttagtaaa attaagatag taaattatgg tatgctaggt tcaattatct tatggctatc
    33061 aactttatct aggacaacaa cctccgttta taggattctt tatttttatt tcgcaatgtc
    33121 cccaatatta ttagaaaagt ggagtagtgt acttgattct gaaaaattag taacaaaggg
    33181 tttggtttcg ttgaacggtt tctttttttc aatctcatat gtacttaaaa atctgtttag
    33241 aatagattat tcgcaaagag tattagaagc atacacaatg attgcgaata ctgatgcaat
    33301 ctggtataat attgcacctg gtttgaccaa ggcaaatgca tatgtctctc tgttttggtt
    33361 cttttatgcg gatggacgtt tactaggagt tttaatagga tcccttctat atggtacctt
    33421 ttgtggttat atcttttgca ggtatatcca gcaacaaaat aaaaagaatt tggctatgtt
    33481 actatttatt tatcaaggtg tttttttctc ttttattaga tttccgtttt caaaatcaaa
    33541 ttatgcaatt gcattcgtac tcttattatt ttttgctttt aagaagaaag gaatagagaa
    33601 aagtgtttaa tatcaatgac cagtctatta tttatgttgc atgtccttat tttaataaaa
    33661 caggtggaac ggagcttgtc catcaattag tttattctat taatcatttt ggggggaaag
    33721 ctatcgttgc ttattatggt agtgaaagtg ctccaaataa ggtgaatcct gcgtttagag
    33781 aatatgtttc tacgtttgtt gatataaaag atgttattga ctctcttgat aatattatta
    33841 ttttaccgga aattaatccg gatttagctg ctaatctaga gtctattcaa aaagcagtat
    33901 ggtggatgag cgttgacaat tatttgaagc gtaatggtat tttaggttcc ttggaacatt
    33961 ttggactttt acgaacaatt aaattatttg taaaaggaaa tattaaaata ggtggatata
    34021 gaatagataa agagattccc catctttatc aaagtgaata cgccaagcaa tttcttctag
    34081 ctaaaggtgt caaaaagtac tatagattgt ctgattattt aaacgagtct tatattcagc
    34141 gatctatttc aacagacact aaaaaagatg ttattcttta caatcctaaa aaagggattg
    34201 aatttactcg tgagctaatt aaacaggctc cagaattaac gttctctcca attgagaata
    34261 tgtcaactga acaggtgaaa aaattacttt caaaaagcaa agtatatatt gattttggca
    34321 accatcctgg gaaagataga ttcccacggg aggcagcgat atcaggttgt tgtgtgataa
    34381 ctgggaaacg aggttctgca aaatattata aggatattcc tattccagat tcatacaaat
    34441 ttgaagacac tgttgaaaat atccccaaca ttattgagac cctgaaatca tgcttaaaaa
    34501 attatgacaa acatactgtt gactttgaga aatatcaaca atatattaaa tctgaacatg
    34561 atttatttga aagagatgtg aaagaattat tcactaggaa taggggttaa ggttatgtca
    34621 accagaaatt cacttattaa aaattctctt tataatgttg cttatagaat gttaaatatc
    34681 atatttccat tagtatccgc aacatatact gcacggataa ttttagctag tggagttggg
    34741 gaggtctcgt ttgcacaaaa tgttgtttct tactttacaa cgatagctgc tatgggtatt
    34801 ccaaattatg gtatacgaga aattgctaaa actagaaata aagcagaggc tacgaataaa
    34861 gttttttcag agctatttct gattaatgga ttgtctacat tactgtgttc tatagtatat
    34921 ttaattctga ttttgacatt caatagcatt tttgataata catcaatgta tcttgctgtg
    34981 ggtttaacat tagtgtttaa cttccttaat atcgattggt tctatcaagg aaaagaggac
    35041 tatgcataca tcacgaaacg tagtttcagt ataaaactta tttctctttt tagtttattt
    35101 atttttgtta gagatactga cgatgcagtt aactatgcat tgatttctag cttagcaatt
    35161 ggcgggaata atatttttaa tcttgttaat ttaaggaaat ataatattag atttagtttt
    35221 aataatatta agattagaag acacttaaaa cctatttttg ttttgttggg ttcagtgatt
    35281 gctattgaaa tctatactat gctggatacc actatgattg gtgctatggt aggaacgact
    35341 gaggtaggtt attatacaaa ttctatgaag ctagttaaat tgctgataac tgtgattacc
    35401 gctattggag gagtgctttt accacgacta agtgattatt attctaaggg agaatttgaa
    35461 aaattaaatc acatcgttga taaagttttt agaatcatgt tgtttctttt tttaccagcc
    35521 caagttgcat taattctagt tgcaccagta attatgccga ttttatttgg tgatagtttt
    35581 ataccagcag tgttaacact tcaacttact tctttgctta tatgtacatt agggtttagt
    35641 aatttatttg ggactcaaat attactaaca tttggagatg agcgaaagct tttgattagc
    35701 acaattttag gagcgcttag taatatcgct ttgaacctaa ttctgattcc agtaatggct
    35761 caaaatggag cagcgttggc atctgtgatt agtgaaacaa ttgttacttt aacagcatac
    35821 tactatgcga aaaaacgtgt gacaattagg tttgacttag gattttattt gccaactgtt
    35881 gtttcaacaa taatcatggg tggagctata tatgtagtaa tgcaattgta tattggggat
    35941 atagaaaaaa tgttattttc aactttgtta ggaggtgttg tattcctttt aattaacgtt
    36001 tttatgaaga atcctattat atatgaattt acaggtatta taaagagaaa gagataatta
    36061 tgtacgacta tttaatcgtt ggagcgggtt tgtctggagc aatcttcgca cacgaagcta
    36121 caaagcgtgg aaaaaaagta aaagtgattg ataaacgcga tcacattgga gggaacatat
    36181 actgtgagaa tgtagaaggt atcaatgttc ataaatatgg tgcccatatc ttccatactt
    36241 ctaataaaaa agtctgggac tacgtcaatc aatttgctga gtttaacaac tatatcaact
    36301 cacctgtcgc aaactataag ggaagtcttt ataaccttcc tttcaatatg aataccttct
    36361 atgctatgtg gggcacaaaa actccacaag aagtgaagga taagattgct gagcagacag
    36421 ctggtatgaa ggatgttgag ccgaaaaatc tggaagaaca agctatcaag ttgattggtc
    36481 cggatatcta tgaaaagttg atcaagggtt atacagaaaa gcaatgggga cgctcagcga
    36541 tagaacttcc tccatttatc ataaaacgcc ttccagttcg tttaaccttt gataataact
    36601 attttaatga ccgttaccaa gggattccta ttggtggtta caatgtcatc atcgaaaata
    36661 tgctgaaaga tgtagaagtt gaacttggag tagacttttt tgctcatcgt gaagagttgg
    36721 aagcatctgc taacaaagtt gtcttcacag gaatgatcga ccaatatttt gactacaagc
    36781 acggagagtt agaataccgt agccttcgtt ttgagcatga gattttagac gaggaaaatt
    36841 atcaagggaa tgctgtagtg aactatacag agcgtgagat cccttatact cgtatcatcg
    36901 aacacaaaca ttttgaatat ggaatgcagc caaagacagt tatcacgcat gaatatccag
    36961 ctgactggaa gcgtggggac gagccctact atcctattaa cgatgagaaa aataatgcta
    37021 tgtttgctaa ataccaagaa gaagcagcgc agaatgataa agttatcttt tgtgggcgtt
    37081 tagcagatta taagtattac gatatgcatg tggtgattga acgggcgctt gaggttgtgg
    37141 agaaagaatt tagtaattga aaaacaacga agaaaggttg cttattatga aaggtattat
    37201 tctagcaggt ggttcgggaa ctcgcttgta tcctttgact cgagccgcat caaaacaact
    37261 tatgccggtt tatgataaac cgatgattta ctacccactt tcaacattaa tgttggctgg
    37321 gattagggat attttgatta tctcaactcc tcaagatttg cctcgtttta aagagcttct
    37381 tcaagatggt tccgagtttg gtattaaact ttcttatgct gagcaaccaa gtccagatgg
    37441 tttggcacaa gcctttatca ttggggaaga gtttatttct gatgatagcg ttgcgctaat
    37501 cttaggtgat aatatctacc atggttctgg gctttccaag atgctacaaa aggcagcgag
    37561 taaggagtcg ggagcaactg tttttggcta ccatgtcaag gatccagagc gctttggtgt
    37621 ggttgagttt gatcaggata tgaaggctat ttctattgaa gaaaagccag agcaacctcg
    37681 ttcaaactat gcagttacag gtctctattt ctatgataat gatgtagtag agattgccaa
    37741 gagtattaaa ccaagtcctc gtggtgaact ggaaattaca gatgtaaaca aagcttacct
    37801 agatcgtggt gatttgtctg ttgagcttat gggacgtggc tttgcttggc tggatactgg
    37861 aactcatgaa agtttactag aggcttcaca gtacatcgaa acagtccaac ggatgcaaaa
    37921 tgttcaggta gcaaacttag aagaaattgc ctatcgcatg ggttatatca gtcgtgaaga
    37981 tgtattgacc ttagcccaac cacttaagaa aaatgaatac ggacagtatc tgctccgttt
    38041 gattggagaa gcatagatga cagataattt tttcggtaag acgcttgcgg cacgcaaggt
    38101 tgaagctatt ccaggcatgt tggagtttga tatccccgtt catggagata atcgtggctg
    38161 gtttaaagaa aatttccaaa aggaaaaaat gcttccactt ggatttccag agtctttctt
    38221 tgcagaagga aaattgcaaa acaatgtatc cttctcacgt aaaaatgtcc ttcgaggact
    38281 ccacgcagag ccttgggata agtacatctc tgtagcagat ggagggaaag ttctgggttc
    38341 ttgggttgat ctacgcgagg gtgaaacctt tgggaatacc tatcagacag taattgatgc
    38401 aagcaaggga atctttgttc ctcgaggcgt agctaatggc ttccaagttc tatcagatac
    38461 agtgtcatat agctatctgg tcaatgatta ctgggctctc gagctcaaac ccaagtatgc
    38521 ctttgtgaac tacgctgatc caagccttgg tattgaatgg gaaaatattg cagaagcaga
    38581 ggtttcagaa gcagataaac atcatcccct acttaaggat gtaaaacctt tgaaaaaaga
    38641 agatttgtaa aaaggaaaga atatgactga atacaaaaat attatcgtga caggtggagc
    38701 tggctttatc ggttctaact ttgtccatta tgtttacgag aactttccag gtgttcacgt
    38761 gacagtccta gataagttga cttatgctgg aaatcgcgcg aatattgagg aaattttagg
    38821 taatcgtgtt gagttagttg ttggtgacat tgctgatgcg gagttggtag acaagttggc
    38881 tgctcaagca gatgctatcg ttcattatgc agcggaaagc cacaatgata attcgctcaa
    38941 tgatccatcg ccatttattc atactaactt catcggaacc tatactcttt tagaagctgc
    39001 tcgtaagtat gatattcgct tccaccatgt atcgacagat gaagtttatg gggatctccc
    39061 tttacgcgaa gatttgccag gtcatggtga aggaccaggt gagaaattta ctgctgaaac
    39121 aaaatacaac ccaagctctc cgtactcatc aaccaaggca gcctcagatt tgattgtcaa
    39181 agcctgggtg cgttcttttg gagtcaaggc aacgatttcc aactgttcaa ataactacgg
    39241 tccttatcaa catatcgaaa aattcatccc acgtcagatt actaacatcc taagtggaat
    39301 taagccaaaa ctttacggtg aaggtaagaa tgttcgtgac tggattcata ccaatgacca
    39361 ttcttcagga gtttggacaa tcttgacaaa agggcaaatc ggtgaaacct acttgattgg
    39421 ggctgatggt gagaagaaca ataaggaagt tttggaactt atccttaagg aaatgggaca
    39481 agctacggat gcctatgatc atgtgactga ccgtgcagga catgaccttc gctatgcgat
    39541 tgatgccagc aagctccgtg atgagttggg gtggaaacct gaatttacca actttgaagc
    39601 tgggctcaag gcaacaatca agtggtatac agataaccaa gaatggtgga aagcagaaaa
    39661 agaagctgtt gaagccaatt atgctaagac tcaggagatt attacagtat aaaaagcagg
    39721 aaatagctgc tttttattgc tatattgaga agagttacat attagaaagg tctagagatg
    39781 attttaatta caggggcaaa tggccaatta ggaacggaac ttcgctattt attggatgaa
    39841 cgtaatgaag aatacgtggc agtagatgtg gctgagatgg acattaccaa tgaagaaatg
    39901 gttgagaaag tttttgaaga ggtgaaaccg actttagtct accactgtgc agcctacacc
    39961 gctgttgatg cagcagagga tgaaggaaaa gagttggact tcgccatcaa tgtgacgggg
    40021 acaaaaaatg tcgcaaaagc atctgaaaag catggtgcaa ctctagttta tatttctacg
    40081 gactatgtct ttgacggtaa gaaaccagtt ggacaagagt gggaagttga tgaccgacca
    40141 gatccacaga cagaatatgg acgcactaag cgtatggggg aagagttagt tgagaagcat
    40201 gtgtctaatt tctatattat ccgtactgcc tgggtatttg gaaattatgg caaaaacttc
    40261 gtttttacca tgcaaaatct tgcgaaaact cataagactt taacagttgt aaatgaccag
    40321 tacggtcgtc cgacttggac tcgtaccttg gctgagttca tgacctacct agctgaaaat
    40381 cgtaaggaat ttggttatta tcatttgtca aatgatgcga cagaagacac aacatggtat
    40441 gattttgcag ttgaaatttt gaaagataca gatgtcgaag tcaagccagt agattccagt
    40501 caatttccag ccaaagctaa acgtccgcta aactcaacga tgagcctggc caaagccaaa
    40561 gctactggat ttgttattcc aacttggcaa gatgcattgc aagaatttta caaacaagaa
    40621 gtgagataag tagtagaatg attttctagt ctaataaaag aggcagataa tgaactccaa
    40681 aggagcttaa gatgtacgat tatcttgttg ttggtgcagt ctttgcccat gaagcagcct
    40741 tagaaggaaa aaaagtaaaa gttattgaaa aacgaaatca tatcgcgggt aatatctata
    40801 ctcgtgaaga ggaaggaatt caagttcatc aatatggtgc tcatatcttc catacttctg
    40861 ataaggagat ctgggattat gtaaatcagt ttgcagagtt taaccgttat accaattctc
    40921 ctgttgcaaa ctataagggt gagatttata accttccttt taatatgaat accttcaata
    40981 aactctgggg agttgtaacg ccagcagaag tacaggctaa gattgatgaa caacgtgcta
    41041 ttttaaatgg taaaactcct gaaaatttgg aagaacaggc gatttctctt gtaggtacag
    41101 acatctacga aaaattaatc aaagactata cagagaaaca gtgggggcaa accaactact
    41161 gaacttccat cctttattat tcgctgttta ccagtacacc tgacctatga taacaactat
    41221 tttaacgata cctatcaagg gattccaatt ggtggataca ctcaaatagt tgaaaaatgt
    41281 tggatcatga aaatattgat gtagaaacaa atgttgattt ctttgtgaac aaagagcaat
    41341 atctgaaaga ttttcctaag attgtcttta ctggtatgat tgatgaattc tttgactata
    41401 agttgggcga actagagtac cgtagtcttc gttttgaaaa tgagaccttg gatatggaaa
    41461 attaccaagg aaatgcagtt gtgaactata cggatgcaga aaccccatat actcgcatta
    41521 ttgaacacaa acattttgag tttgggagtc aagcaaagac tatcattact aatagaacat
    41581 tctaaaacat gggaaaaagg tgatgagcct tattatccag ttaataatga tcgtaataat
    41641 catttgtata aatcatataa aaaacttgct gatgagcaag ggaatgttat ctttggtggc
    41701 cgcttaggac actatcgtta ttacgatatg caccaagtaa ttggagcagc tttgcagtgc
    41761 gtgagaaatg agttagattc atactcaatg aaaattaaag agcaaactag gaagctagcc
    41821 gcaggttgct caaaacactg ttttgaggtt gcagatggaa gctgacgcgg tttgaagaga
    41881 ttttcgaaga gtataaacaa gtaaaactga ctaccagtta ttatttagaa atagtattaa
    41941 aaattccttg actatatgat atcccaaatc att
//
LOCUS       DAVIME010000016        39998 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVIME010000016 DAVIME010000000
VERSION     DAVIME010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39998
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.016"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            650..2803
                     /locus_tag="VV588_000873"
     CDS             650..2803
                     /locus_tag="VV588_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU7083243.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLFSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNSLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2816..4165
                     /locus_tag="VV588_000874"
     CDS             2816..4165
                     /locus_tag="VV588_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU7083244.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQSEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQFFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4335..5042
                     /locus_tag="VV588_000875"
     CDS             4335..5042
                     /locus_tag="VV588_000875"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU7083245.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIVG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5244..8969
                     /locus_tag="VV588_000876"
     CDS             5244..8969
                     /locus_tag="VV588_000876"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU7083246.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVCVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9062..10504
                     /locus_tag="VV588_000877"
     CDS             9062..10504
                     /locus_tag="VV588_000877"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU7083247.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10541..11563
                     /locus_tag="VV588_000878"
     CDS             10541..11563
                     /locus_tag="VV588_000878"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU7083248.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11560..12105
                     /gene="purN"
                     /locus_tag="VV588_000879"
     CDS             11560..12105
                     /gene="purN"
                     /locus_tag="VV588_000879"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU7083249.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12189..12698
                     /locus_tag="VV588_000880"
     CDS             12189..12698
                     /locus_tag="VV588_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU7083250.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12723..14270
                     /gene="purH"
                     /locus_tag="VV588_000881"
     CDS             12723..14270
                     /gene="purH"
                     /locus_tag="VV588_000881"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU7083251.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDATYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14392..15654
                     /gene="purD"
                     /locus_tag="VV588_000882"
     CDS             14392..15654
                     /gene="purD"
                     /locus_tag="VV588_000882"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU7083252.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKTFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            15845..16336
                     /gene="purE"
                     /locus_tag="VV588_000883"
     CDS             15845..16336
                     /gene="purE"
                     /locus_tag="VV588_000883"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU7083253.1"
                     /translation="MTKPIISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTP
                     DLMFKHAEEAYSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYS
                     IVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSN
                     ELI"
     gene            16323..17414
                     /gene="purK"
                     /locus_tag="VV588_000884"
     CDS             16323..17414
                     /gene="purK"
                     /locus_tag="VV588_000884"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU7083254.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALAESADCVLEEFVNFALEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVAENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            17424..17651
                     /locus_tag="VV588_000885"
     CDS             17424..17651
                     /locus_tag="VV588_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU7083255.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            17714..19012
                     /gene="purB"
                     /locus_tag="VV588_000886"
     CDS             17714..19012
                     /gene="purB"
                     /locus_tag="VV588_000886"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU7083256.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19067..23005)
                     /gene="strH"
                     /locus_tag="VV588_000887"
     CDS             complement(19067..23005)
                     /gene="strH"
                     /locus_tag="VV588_000887"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU7083257.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKADVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYDDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKIISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAVTHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEDIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKVLPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23318..24034)
                     /locus_tag="VV588_000888"
     CDS             complement(23318..24034)
                     /locus_tag="VV588_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU7083258.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIEFISCDRDH"
     gene            24382..26169
                     /locus_tag="VV588_000889"
     CDS             24382..26169
                     /locus_tag="VV588_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU7083259.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYIAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEERGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26166..26642
                     /locus_tag="VV588_000890"
     CDS             26166..26642
                     /locus_tag="VV588_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU7083260.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26670..27575
                     /locus_tag="VV588_000891"
     CDS             26670..27575
                     /locus_tag="VV588_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU7083261.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27562..28377
                     /locus_tag="VV588_000892"
     CDS             27562..28377
                     /locus_tag="VV588_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU7083262.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28384..28788
                     /locus_tag="VV588_000893"
     CDS             28384..28788
                     /locus_tag="VV588_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7083263.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29087..30247
                     /locus_tag="VV588_000894"
     CDS             29087..30247
                     /locus_tag="VV588_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU7083264.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATILVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEY"
     gene            30369..31406
                     /locus_tag="VV588_000895"
     CDS             30369..31406
                     /locus_tag="VV588_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU7083265.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSITPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31613..32467
                     /locus_tag="VV588_000896"
     CDS             31613..32467
                     /locus_tag="VV588_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU7083266.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKEELLTIVQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            32617..32874
                     /locus_tag="VV588_000897"
     CDS             32617..32874
                     /locus_tag="VV588_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU7083267.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33042..33170)
                     /locus_tag="VV588_000898"
     CDS             complement(33042..33170)
                     /locus_tag="VV588_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HEU7083268.1"
                     /translation="MDRTDEVSNHIYGKVKLMWFEEIFEEYKFLHNKTHITKVLMN"
     gene            complement(33204..33296)
                     /locus_tag="VV588_000899"
                     /pseudo
     CDS             complement(33204..33296)
                     /locus_tag="VV588_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33332..33628)
                     /locus_tag="VV588_000900"
                     /pseudo
     CDS             complement(33332..33628)
                     /locus_tag="VV588_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(33618..33779)
                     /locus_tag="VV588_000901"
     CDS             complement(33618..33779)
                     /locus_tag="VV588_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU7083269.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            33849..34613
                     /locus_tag="VV588_000902"
     CDS             33849..34613
                     /locus_tag="VV588_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU7083270.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            35226..36605
                     /locus_tag="VV588_000903"
     CDS             35226..36605
                     /locus_tag="VV588_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU7083271.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36619..37284
                     /locus_tag="VV588_000904"
     CDS             36619..37284
                     /locus_tag="VV588_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU7083272.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37398..37493
                     /locus_tag="VV588_000905"
                     /pseudo
     CDS             37398..37493
                     /locus_tag="VV588_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            37639..38178
                     /locus_tag="VV588_000906"
     CDS             37639..38178
                     /locus_tag="VV588_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU7083273.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            38245..38655
                     /locus_tag="VV588_000907"
     CDS             38245..38655
                     /locus_tag="VV588_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU7083274.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            38771..>39998
                     /gene="pavB"
                     /locus_tag="VV588_000908"
     CDS             38771..>39998
                     /gene="pavB"
                     /locus_tag="VV588_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU7083275.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETPGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVALD
                     GNVAGKEKQALIDQFRA"
BASE COUNT        11029 a         7804 c         9344 g        11821 t
ORIGIN      
        1 ttaattagaa aaaaattttt aaagtcttcg gagaagaaaa cagaaaaatc tgttaaaaaa
       61 taatcaaaac tataaatgat gaatctgaat caaaattatt ttgcgcatgt aaagaggagt
      121 cttatagtaa cgagtcaaaa aaggagtaac tatgaatcgt aatttagaac ggtgttatct
      181 attctgacta ggaatagatc ataccagagg tagcttagaa atagcagaga cattagaaat
      241 tgaagtaata aataggatgt cgtaagtgtt actatcaatg atttatttgt ttcaagcttg
      301 cctagggtga cagtaaaaaa tcaatttcct ttcaatagca tatttttagt gggcaggact
      361 cttgttctgc ctattttttt atccaaaaag tgcagttggg agggagatag gctcatttgg
      421 gaaggaagtc cagtttttgt ttagtgattg gggtaagata gttgttatca gatgagttta
      481 tactcttcga aaatcaaatt caaaccacgt caacgtcgcc ttgccgtata tatgtgactg
      541 acttcgtcag tcctatctac aacctcaaaa cagtgttttg agcagcctgc ggctagtttc
      601 ctagtttgct ctttgatttt cattgagtat tagggaaaag gagatgaata tgaaatttgg
      661 gaaacgtcac tatcgtccgc aagtggatca gatggactgc ggtgtagctt cattagccat
      721 ggtttttggc tactatggta gttattattt tttggctcac ttgcgagaat tggctaagac
      781 gaccatggat gggacgacgg ctttgggctt ggtcaaggtg gcagaggaga ttggttttga
      841 gacgcgagcc attaaggcgg atatgacgct ttttgacttg ccggatttga cttttccttt
      901 tgttgcccat gtgcttaagg aagggaaatt gctccactac tatgtggtga ctgggcagga
      961 taaggatagc attcatattg ccgatccaga tcccggggtg aagttgacta aactgccacg
     1021 tgagcgtttt gaggaagaat ggacaggagt gactcttttt atggcaccta gtccagacta
     1081 taagccttat aaggaacaaa aaaatggtct gctctctttt atccctatat tagtgaagca
     1141 gcgtggcttg attgccaata tcgttttggc aacactcttg gtaaccgtga ttaacattgt
     1201 gggttcttat tatctgcagt ctatcattga tacctatgtg ccagatcaga tgcgttcgac
     1261 actagggatt atttctattg ggctagtcat cgtctacatc ctccagcaaa tcttgtctta
     1321 cgctcaggag tatctcttgc ttgttttggg gcaacgcttg tcgattgacg tgattttgtc
     1381 ctatatcaag catgtttttc acctccctat gtccttcttt gcgacacgca ggacagggga
     1441 gatcgtgtct cgttttacag atgctaacag tatcatcgat gcgctggctt cgaccatcct
     1501 ttcgattttc ctagatgtgt caacggttgt cattatttcc cttgttctat tttcacaaaa
     1561 taccaatctc tttttcatga ctttattggc gcttcctatc tacacagtga ttatctttgc
     1621 ctttatgaag ccgtttgaaa agatgaatcg ggataccatg gaagccaatg cggttctgtt
     1681 ttcttctatc attgaggaca tcaacggtat tgagactatc aagtccttga ccagtgaaag
     1741 tcagcgttac caaaaaattg acaaggaatt tgtggattat ctgaagaaat cctttaccta
     1801 tagtcgagca gagagtcagc aaaaggctct gaaaaaggtt gcccatctct tgcttaatgt
     1861 cggcattctc tggatggggg ctgttctggt catggatggc aagatgagtt tggggcagtt
     1921 gattacctat aataccttgc tggtttactt taccaattct ttggaaaata tcatcaatct
     1981 gcaaaccaag cttcagacag cgcaggttgc caataaccgt ctaaatgaag tgtatctagt
     2041 agcttctgag tttgaggaga agaaaacagt tgaggatttg agcttgatga agggagatat
     2101 gaccttcaag caggttcatt acaagtatgg ctatggtcga gacgtcttgt cggatatcaa
     2161 tttaaccgtt ccccaagggt ctaaggtggc ttttgtgggg atttcagggt caggtaagac
     2221 gactttggcc aagatgatgg ttaattttta cgacccaagt caaggggaga ttagtctggg
     2281 tagtgtcaat ctcaatcaga ttgataaaaa agccctgcgc cagtacatca actatctgcc
     2341 tcaacagccc tatgtcttta acggaacgat tttggagaat cttcttttgg gagccaagga
     2401 ggggacgaca caggaagata tcttacgggc ggtcgaattg gcagagattc gagaggatat
     2461 cgagcgcatg ccactgaatt atcagacaga attgacttcg gatggggcag ggatttcagg
     2521 tggtcaacgt cagagaatcg ctttggcgcg tgctctcttg acagatgcgc cggtcttgat
     2581 tttggatgag gcgactagca gtttggatat tttgacagag aagcggattg tcgataatct
     2641 catagctttg gacaagacct tgattttcat tgctcaccgc ttgactattg ctgagcggac
     2701 agagaaggta gttgtcttgg atcagggcaa gattgtcgaa gaaggaaagc atgctgattt
     2761 gcttgcacag ggtggctttt acgcccattt ggtcaatagc tagaaagagg agaggatgaa
     2821 accagaattt ttagaaagtg cggagtttta taatcgtcgt taccataatt tttccagtag
     2881 tgtgattgta cccatggccc ttctgctcgt gtttttactt ggctttgcaa ctgttgcaga
     2941 gaaggagatg agtttgtcca ctagagctac tgtcgaaccc agtcgtatcc ttgcaaatat
     3001 ccagtcaact agcaacaatc gtattcttgt caatcatttg gaagaaaata agctggttaa
     3061 gaagggggat cttttggttc aataccaaga aggggcagag ggtgtccaag cggagtccta
     3121 tgccagtcag ttggacatgc taaaggatca aaaaaagcaa ttggagtatc tgcaaaagag
     3181 cctgcaagaa ggggagaacc actttccaga ggaggataag tttggctacc aagccacctt
     3241 tcgcgactac atcagtcaag caggcagtct tagggctagt acatcgcaac aaaatgagac
     3301 catcgcgtcc cagaatgcag cagctagcca aacccaatcc gaaatcggca acctcatcag
     3361 tcaaacagag gctaaaattc gcgattacca gacagctaag tcagctattg aaacaggtgc
     3421 ttccttggcc ggtcagaatc tagcctactc tctttaccag tcctacaagt ctcagggcga
     3481 ggaaaatccc caaactaagg ttcaggcagt tgcacaggtt gaagcacaga tttctcagtt
     3541 agaatctagt cttgctactt accgtgtcca gtatgcaggt tcaggtaccc agcaagccta
     3601 tgcgtcaggg ttaagcagtc aattggaatc ccttaaatcc caacacttgg caaaggttgg
     3661 tcaggaattg acccttctag cccagaaaat cttggaggca gagtcaggta agaaggtaca
     3721 gggaaatctt ttagacaagg ggaaaattac ggcgagtgag gatggggtgc ttcatcttaa
     3781 tcctgagacc agtgattcta gcatggttgc agaaggtgcc ctactagccc aactttatcc
     3841 atctttggaa agagaaggga aagccaaact cacagcctat ctaagttcaa aagatgtagc
     3901 aagaatcaag gtcggtgatt ctgttcgcta tactacgact catgatgccg ggaatcaatt
     3961 ttttctagat tctactatta caagtattga tgcgacagct actaagactg agaaagggaa
     4021 tttctttaaa atcgaggcgg agactaatct aacttcggag caggctgaaa aacttaggta
     4081 cggggtggaa ggccgtctac agatgattac gggcaagaaa agttatctac gttattattt
     4141 ggatcaattt ttgaacaaag agtaatgttc gtgtttttag agttaaataa tttttaaact
     4201 gtgagaaaga ttcttcttgc agttttttct ttacaatttt tgaaaaacat atgctattta
     4261 ttcggttaaa ttcttgtgtt ttttggtttt ttgtggtaaa atgtgctcaa gtaatacgaa
     4321 aggcgaactt taaaatgtca aaacaattga tctattcggg aaaagctaaa gatatctata
     4381 caactgagga tgaaaatctt attatttcaa cttacaagga ccaggcgact gctttcaacg
     4441 gtgtcaagaa ggagcagatt gtaggtaagg gagtcttgaa taatcagatc tcatctttta
     4501 tttttgagaa attaaatgcg gctggtgtgg cgactcactt tgtggagaaa ctttcagaca
     4561 cggaacaact caataaaaag gttaagatta ttcctttgga agtcgtgctc cgcaactata
     4621 ctgctggttc cttttcaaaa cgttttggtg tggatgaggg aatcgccttg gagactccga
     4681 ttgtcgaatt ttactacaaa aatgatgatt tggatgatcc atttatcaat gatgagcatg
     4741 tgaaattcct acagattgcg ggtgaccagc agattgccta cttgaaggaa gaaacgcgtc
     4801 gtatcaatga actattgaaa gtctggtttg ctgagattgg gcttaaattg attgacttta
     4861 agctagagtt cggttttgac aaggatggca agattatctt ggcagacgaa ttttcaccag
     4921 ataactgccg cttgtgggac gctgatggca accacatgga taaggatgtt ttccgtagag
     4981 gattgggaga actaaccgac gtttatgaga ttgtttggga aaagttgcag gaattgaaat
     5041 aatctgtttg caacggaaaa ccttcgtctc tcaactaaaa ggactcaggc tgaaaaggtc
     5101 ccccagacct tttcactctg tagagaacta ggtgaactaa cagatgttta cgaaattgtc
     5161 tgggaaaagt tgcagggttt aaaataacaa cctcaaggct gtttgggaat attgcaagag
     5221 ctgaaataaa ggaataagaa ttgatggata aacgtatttt tgttgaaaaa aaggctgatt
     5281 ttcaggtcaa gtcagagagt ttggttagag agctccagca caacttggga ctgtcaagct
     5341 tgaaaagtat tcgtattgtg caagtatatg atgtatttga cttggctgag gacttgtttg
     5401 cacctgcaga gaagcacatt ttctctgagc agggaaccga ccatgtttta gatgaagtat
     5461 ctgtgcaggc ggatcttgct aactatgctt tctttgccat tgaaagtctg ccagggcagt
     5521 ttgaccagcg tgcagcttcg tcacaggaag ccttgctttt gttgggaagt tcgagtgacg
     5581 tgacagtcaa cacagcccaa ctttacttgg tgaataaaga tattgatgcg actgagttgg
     5641 aagctgtcaa aaactacctg ctcaatccag ttgattctcg tttcaaggat atcacgacag
     5701 ggattgccaa gcaggagttt tcagagtcag acaagaccat tccaaaattg actttctttg
     5761 aaagctatac agcagaagac tttgctcgct acaaggccga gcaagggatg gccatggaag
     5821 tggatgattt gctctttatc caagactact ttaagtcaat cgggcgcgtg ccaactgaga
     5881 ctgaactcaa ggttttggac acttactggt ctgaccactg ccgtcatacg acttttgaga
     5941 cagagttgaa acacatcgac ttttcagctt ctaaatttca aaagcaattg cagtcaacct
     6001 atgacaagta tattgccatg cgcgaggagt taggtcggtc tgaaaaacca caaaccttga
     6061 tggatatggc gactattttc ggtcgttatg agcgtgctaa tggacgattg gatgatatgg
     6121 aagtctctga cgaaatcaat gcctgctcag ttgaaattga agtggatgtt gatggtgtca
     6181 aggaaccttg gctcctcatg tttaaaaatg aaacccacaa ccatccaaca gaaattgagc
     6241 catttggtgg agcggctacc tgtatcggtg gagctattcg tgatccgttg tcaggccgtt
     6301 cctatgttta ccaagccatg cgtatttcag gtgctggtga tattacagca ccgatttcgg
     6361 aaactcgtgc tgggaaattg ccacaacaag tcatttctaa aacagcagct catggttatt
     6421 cttcatatgg taaccagatt gggcttgcca caacctacgt tcgtgaatac ttccacccag
     6481 gctttgtagc taaacgtatg gaacttggtg ccgttgttgg tgcggctccc aagggcaatg
     6541 ttgtccgtga aaaacctgaa gcaggtgatg tgatcatcct tctcggaggc aaaacaggtc
     6601 gtgatggtgt cggtggtgcg acgggctctt ctaaggttca aacagttgag tctgtagaga
     6661 ctgctggtgc tgaggttcaa aaaggaaatg ccatcgaaga acgcaagatt cagcgcctct
     6721 tccgtaatgg caatgtcact cgtctgatca agaagtccaa tgactttggg gcaggcggcg
     6781 tctgtgtggc tatcggtgaa ttggcagacg gtcttgaaat cgacctcaac aaggtgcctc
     6841 ttaaatacca gggcttgaat ggtacagaaa ttgccatctc tgaatcacaa gaacggatgg
     6901 cggtcgtggt tcgtcctgaa gatgtggata ccttcgttgc cgaatgtaac aaagaaaata
     6961 ttgatgctgt tgtggtggcg acagtaactg aaaaaccaaa tcttgtcatg cactggaatg
     7021 gtgagacaat cgttgacttg gagcgtcgtt tccttgacac caatggtgtg cgcgtggttg
     7081 tcgatgccaa agttgtggac aaggatgtca aactcccaga agagcgtcaa acatctgctg
     7141 aaacactgga atcagatacc cttacggttc tatctgacct caaccatgca agtcaaaaag
     7201 gattacagac tatctttgac tgctctgttg gacgctcaac ggttaatcac ccacttggtg
     7261 gtcgttacca actcacacca actgaggcat ctgtgcagaa attgccagtt caacacggtg
     7321 tgactcatac tgcgtcggtc attgctcaag gtttcaaccc atatgtagct gaatggtctc
     7381 cataccacgg tgctgcttat gcggttatcg aagcaactgc tcgtttggtg gctgctggtg
     7441 ccaactggtc caaggctcgt ttctcttacc aagagtattt cgagcgtatg gataaacaag
     7501 cagagcgttt cggtcagcca gtagctgctc ttctaggttc tattgaagca caaattcagc
     7561 ttggcttgcc atctatcggt ggtaaggact ccatgtctgg tacctttgaa gaattgaccg
     7621 ttccgccaac cttggttgcc tttggggtga cgacggcaga tagccgtaag gtgctctctc
     7681 cagaatttaa agctgttggg gaaaatatct actacatccc aggtcaagcc ctctctgcag
     7741 agattgattt tgacttgatt aagaaaaatt ttactcagtt tgaagccatc caagctgacc
     7801 ataaagtgac atctgcatca gctgtcaaat acggtggtgt agttgaaagt ttggctcttg
     7861 ctacctttgg aaactatatt ggtgcagagg tgaccttgcc tgaacttaaa acagctttga
     7921 cagctcaatt aggcggcttt gtcttcacat ctcctgaaga aattgctgga gtagagaagg
     7981 ttggacaaac gaaagcagac tttacactga ctgtcaacgg tgtgaagcta gatggacaca
     8041 agcttgacag tgcatttcaa gggacattgg aagaagttta cccaacagaa tttacccaag
     8101 cgaaagaact agaagaagta ccagctgtgg catcagatgt tgtgattaaa gccaaagaaa
     8161 aggttgaaaa acctgtggtt tacatcccag tctttccagg aaccaactca gaatatgatt
     8221 cagctaaggc cttcgaaaaa gaaggtgcag aggtcaattt ggtgccattc gtgaccttga
     8281 atgaagaagc tattgtcaag tcagttgaaa ctatggttga caatatcgac aagactaata
     8341 ttctcttctt tgctggtgga ttctcggctg cggatgaacc agatggttca gctaagttta
     8401 tcgtcaatat cctgcttaat gaaaaagtgt gtgtggctat tgatagcttt atcgcccgtg
     8461 gtggtttgat tatcggtatt tgtaatggat tccaagcctt agtcaaatcg ggtctcctac
     8521 cctacggaaa ctttgaagct gctaacagta ctagcccaac cctcttctac aatgatgcca
     8581 accaacacgt ggccaagatg gtggaaactc gcattgccaa taccaactca ccatggttgg
     8641 ctggtgtgca agtgggcgat atccacgcta ttcctgtttc gcacggtgaa gggaagtttg
     8701 tcgtgacggc tgaggaattt gcagagctcc gtgacaatgg acaaattttc agccaatacg
     8761 ttgactttaa cggtaaacca agtatggatt ctaagtacaa tccgaatggt tctgtccatg
     8821 ccatcgaagg aattaccagc aagaatggtc aaatcatcgg taagatgggc cactcagaac
     8881 gttatgagga tggtcttttc caaaatatcc caggcaataa agaccaacac ctgttcgcat
     8941 cagcggttaa acatttcact ggaaaataag acttacagat tttctaatag atagtatcag
     9001 taatgtaaaa gtcatgtaaa tctagctctt gatgattaca aatgaaaatt aggtataaaa
     9061 aatgacatac gaagtaaaat ctcttaatga agaatgtggt gttttcggta tttggggaca
     9121 tccagatgct gctaagttga cctattttgg actccacagt cttcaacacc gtggtcagga
     9181 gggggcagga atcctctcca atgatcaagg acaactgaag cgccatcgtg acatggggct
     9241 tttatcagaa gttttcagaa atccagccaa tttggataaa ttgacaggag ctggtgcgat
     9301 tgggcatgtg cgttatgcga ctgctggcga agcttctgtt gataacatcc aacccttcct
     9361 cttccgtttt cacgatatgc agtttggttt ggctcataat ggaaatctga ccaatgcagc
     9421 ctctctcaag aaagaactgg aacaaagagg agcaattttc agcgcgactt cggactctga
     9481 aatcttggct cacctcattc gtcgcagtca taatcctagc ctgatgggca aaatcaagga
     9541 agcgctcagc cttgtcaaag gtggttttgc ctatatcttg ctgtttgagg acaagttgat
     9601 tgcggctctt gaccctaatg gctttcgtcc gctttctatc gggaaaatgg ccaacggagc
     9661 ggtggttgtt tcctctgaaa cctgtgcttt tgaggtcatt ggtgccgagt ggattcgtga
     9721 tttgaagcca ggtgagattg tgatcattga tgacgagggc attcagtatg acagctatac
     9781 agatgatacc cagttggcga tttgttctat ggagtatatc tactttgccc gccctgattc
     9841 taatatccac ggtgtcaatg tccatacggc acgtaagaga atgggagcgc aattggcgcg
     9901 agaatttaag catgaggcag atattgtagt tggtgtgccc aattcttccc taagcgcggc
     9961 tatgggattt gcggaagaat caggcttacc aaatgaaatg ggtctgatca aaaaccaata
    10021 cacccagcga acttttatcc aaccgactca agaattgcgg gagcaaggag tgcggatgaa
    10081 actgtctgct gtttcgggtg ttgtcaaagg caaacgtgtg gttatggtgg atgattccat
    10141 tgtacgtgga acaacctctc gtcgtatcgt tcagctcttg aaagaagcgg gtgcgactga
    10201 ggttcacgtt gccattggaa gtcctgcact agcgtatcca tgtttctacg ggattgatat
    10261 ccagacccgt caggagctga ttgcagccaa tcatacggtc gaagaaactc gccaaatcat
    10321 tggtgcggac agtctgactt atctttcaat tgatagcttg attgagtcga ttggtatcga
    10381 aacagatgcg ccgaacggtg gtctctgtgt cgcttacttt gacggtgact acccaacgcc
    10441 tctctatgac tacgaagaag actatcgtag aagtttggaa gaaaagacca gtttttacaa
    10501 gtaggcgaca gattctccat taaagaaaag gaaaaaacaa atgacaaata aaaatgcata
    10561 tgcccagtcg ggtgtggatg ttgaagcggg ttatgaagtt gttgaacgga ttaaaaagca
    10621 cgtggcccgt acggagcgtg caggtgtcat gggagctctt ggtggctttg gtggtatgtt
    10681 tgacctttcc aagactgggg ttaaagaacc cgtcttgatt tcagggactg acggtgtcgg
    10741 aaccaagctc atgttggcta tcaagtacga caagcacgat accatcgggc aggactgtgt
    10801 ggccatgtgt gtcaacgaca tcattgctgc aggtgcggaa cccctctatt ttctcgacta
    10861 cgtagcgaca gggaagaatg aaccagctaa gctagaacaa gtggttgctg gtgtggcaga
    10921 aggttgtgtg caggctggtg ctgccctcat cggtggggaa acggctgaaa tgccgggcat
    10981 gtacggcgaa gacgactatg acttggctgg ttttgcggtc ggtgtggctg aaaaatctca
    11041 aatcattgac ggttcaaagg tggtagaggg agatgttctt ctcggacttg cttcaagtgg
    11101 gattcactca aatggttact ctttggttcg tcgtgtcttt gcggattaca caggtgagga
    11161 agtcctacca gaattggaag gcaagaaact taaggaagtt ctacttgagc cgactcgtat
    11221 ctatgtcaag gctgtcttgc cgctcatcaa agaagagttg gtcaacggca ttgcccacat
    11281 cacaggtggt ggctttatcg aaaatgtccc tcgtatgttt gcagatgacc tagctgctga
    11341 aattgatgaa agcaaagttc cagtgcttcc aattttcaaa gcccttgaaa aatatggtca
    11401 gattaaacac gaagaaatgt ttgaaatctt caatatgggt gtgggactta tgttggcggt
    11461 cagccctgaa aatgtagagc gtgtaaaaga attgttggat gaagcagtct atgaaattgg
    11521 tcgcatcgtc aagaaagaaa acgaaagtgt cattatcaaa tgaaaaaaat agcggttttt
    11581 gcctctggta atggctcaaa ttttcaggtg attgccgaag aatttccagt ggagtttgtc
    11641 ttttcagacc atcgtgatgc ctatgtgctt gagcgtgcaa agcagctcgg cgttctgtcc
    11701 tatgcttttg aactcaagga gtttgagagc aaggcagact acgaagcagc ccttgtcgaa
    11761 ctcttggaag aacaccagat tgacttggtt tgcctagcag gctacatgaa aatcgttgga
    11821 ccaaccttat tgtcggctta tgaaggtcgg attgtcaaca ttcatccagc ctacttgcca
    11881 gaatttccag gagctcatgg gattgaggat gcttggaatg ctggcgtggg tcagtctggt
    11941 gtgaccattc actgggtgga ttcgggtgtg gatacaggcc aggtcatcaa acaggttcgt
    12001 gtgccacgac tagctgatga taccattgac agatttgaag ctcgcatcca tgaagcagag
    12061 tacaggctgt atccggaagt agtgaaggct ctatttacag attgactttt tgatgattca
    12121 tatgatatct ttgattttaa attggagtca gtgtttgttg aagacggctt caaacggagg
    12181 tatttgtaat attagaatct aaaaaaacaa ctcgatatgt attttatgtc tatctgatgt
    12241 tattaacttg gggaatctta tttaagtttg aaacaaatcc tgaatttata gcatttttct
    12301 tagctccaag gtatatcaat tggattccat tttcagaacc actaatagtc gatggaaaaa
    12361 ttgtttttgc tgaaatgtta tttaatctga tttcctttat tccattaggt gtttgtttcc
    12421 ctttgataaa aactaattta tctagtttaa gaatagtcgg gacaggtttc ttgattagtt
    12481 tattgtttga gtgcttacag tatattttag caataggtat aacagatata acggatttga
    12541 ctttaaatac gctaggtgtc tgtgtaggct tactgattta tcaaattttt ataagagtgt
    12601 tcaaatcaca gactagaaaa tggatcaata tcttaggtat gcttagcctt ggttttgctt
    12661 atcttgtttt actgttactg catttaattg gtgtttaact aatgattaaa aaggagaata
    12721 taatgactaa acgcgtctta atcagcgtct cagacaaagc gggcattgtt gaatttgccc
    12781 aagaactcaa aaaacttggt tgggagatta tctcgacagg tggaactaag gttgcccttg
    12841 ataatgctgg ggtggatacc attgctatcg atgatgtgac tggtttccca gaaatgatgg
    12901 acggtcgtgt gaagaccctc cacccaaata tccacggggg gcttctcgct cgtcgtgact
    12961 tggatagcca cttggaagcg gctaaggaca acaagattga gctcattgac cttgtggtgg
    13021 tcaaccttta cccatttaag gaaactatcc ttaaaccaga tgcgacttat gctgatgcag
    13081 ttgaaaatat cgatattggt gggccatcta tgcttcgttc agcagcgaaa aatcatgcca
    13141 gtgttacagt tgtggtagat cctgctgact acgctgtggt tttggacgaa ttggcagcaa
    13201 acggcgaaac ctcttatgaa actcgccaac gtttagcagc caaagtattt cgtcacacag
    13261 cggcttatga cgccttgatt gcagaatact tcacagctca agtgggtgaa agcaagcctg
    13321 aaaaactcac tttgacttat gacctcaagc aaccaatgcg ttacggtgag aatcctcaac
    13381 aagacgcgga cttttaccag aaagctttgc ctacagacta ctccattgct tcagccaaac
    13441 agctcaacgg gaaagaattg tcatttaata atatccgtga tgcagatgct gctatccgta
    13501 tcatccgtga cttcaaagat agtccaaccg ttgtggctct caaacacatg aatccatgtg
    13561 gaattggtca agctgatgac atcgagactg cttgggacta cgcttatgag tctgacccag
    13621 tgtctatctt tggtgggatt gtcgtcctca accgtgaggt ggatgctgcg acagctgaga
    13681 agatgcacgg cgttttcctc gaaatcatca ttgcaccaag ctatacggat gaagcgctag
    13741 ccattttgat caataaaaag aaaaacttgc gtatccttgc cttgccattt aatgctcaag
    13801 aggctagcga agtggaagca gaatacacag gtgtagtcgg tggacttctc gtgcaaaatc
    13861 aagacgtggt caaggaaagc ccagctgact ggcaagtggt gaccaaacgt cagccaaccg
    13921 agacagaagc gactgctctt gagttcgctt ggaaggctat caagtacgtc aaatcaaatg
    13981 gtattatcgt gaccaacgac cacatgacac ttggtgttgg tccaggtcaa accaaccgtg
    14041 tggcttctgt tcgccttgcc attgaccaag ccaaagatcg tctggacggg gcggtccttg
    14101 cttcagatgc cttcttccca tttgcggata acgtggaaga aatcgctaaa gcaggaatta
    14161 aggccatcat ccagcccggt ggctctgtcc gtgaccaaga atccatcgaa gcagcggata
    14221 aatacggctt gactatggtc tttacaggtg tgagacattt tagacattaa gaagataaaa
    14281 gggaagaaaa cagtttcttt ccttttttgg cttaaaatgc taactgaaac aagattaaaa
    14341 cgaacttttt tgatataata ttggtaaata attcgcaaaa gaggttgagg aatgaaactg
    14401 cttgttgtcg gttcgggtgg tcgtgagcat gcgattgcta aaaagttact tgaatcaaaa
    14461 gatgtggaaa aagtctttgt agctcctggg aatgatggga tgactctgga tggtttggaa
    14521 ttggtaaata tctctatttc cgaacattct aaattgattg acttcgcaaa gaccaatgat
    14581 gttgcttgga cctttatcgg tccagatgat gcccttgctg ctggtatcgt ggatgatttt
    14641 aaccaagctg ggcttaagac ctttggtccg actagggctg cagcggagct ggagtggtcc
    14701 aaggattttg ccaaggaaat catggtcaaa tatggtgttt cgacagcagc ctatggcaca
    14761 ttttcagatt tcgaggaagc aaaggcttat atcgaaaagc atggtgcgcc tatcgtagtc
    14821 aaggcggatg gcttggcgct tgggaagggt gtcgtcgttg ctgagacggt tgagcaagcg
    14881 gtcgaagccg ctcatgagat gcttttggac aataaatttg gtgactcagg tgcgcgcgtg
    14941 gttattgagg aattccttga aggagaggaa ttttcactct ttgcctttgt caatggtgat
    15001 aagttctaca tcatgccaac ggctcaggac cacaaacgtg cctacgatgg cgacaaaggg
    15061 cctaacacgg gtggtatggg tgcctatgcg ccagttccac acttaccaca gagtgtagtt
    15121 gatacagcgg ttgacaccat tgtcaagcca gttctagaag ggatgattaa agaaggtcgc
    15181 ccttatctgg gagttcttta cgcagggctt atcctgacag ctgatggacc gaaagtcatc
    15241 gagttcaacg ctcggttcgg agatccagaa actcagatta tcttgcctcg cttaacctct
    15301 gactttgctc aaaatatcac agatatcctg gatagcaagg agccaaatat catgtggacg
    15361 gacaagggtg tgactctggg tgtggttgtc gcatccaagg gctacccgct agactatgaa
    15421 aggggcgttg agttgccagc caagacagaa ggcgatgtca tcacctacta tgcaggggct
    15481 aagtttgcgg aaaatagcag agcactgctc tcaaacggcg gacgagttta tatgctcgtt
    15541 accacagcag ataccgtcaa agaagcccaa gccagcatct accaagaact atcccaacaa
    15601 aaaatagaag gactcttcta ccgaacagat atcggaagca aggcaattaa gtaaagatat
    15661 aagaataacg cgccgtagtc gccaaacacg ataatggtcg tcgtggtgaa aagaccagaa
    15721 cagtgaatgt tctggtcagg gggaaatttg gagaccgtag gctcaaagtt taggaatgaa
    15781 accgaaggtt tgcttccgcc tccatcacct aagatcatta ttaaaaaaga agaaaaggaa
    15841 aattatgacc aaaccaatta tttccatcat catgggctca aaatccgatt gggcaaccat
    15901 gcaaaaaaca gcagaagtct tagaccgctt cggtgtagcc tacgaaaaga aagttgtttc
    15961 tgcccaccgt acacctgatc tcatgttcaa acatgcagaa gaagcatata gccgtggtat
    16021 taaggtcatc atcgcaggtg ctggaggcgc agcccacttg ccaggaatgg tagctgccaa
    16081 aacaaccctt cctgtcatag gggtacctgt caagtctcgt gctcttagtg gagtggattc
    16141 actctattct atcgttcaga tgccgggtgg ggtgcctgtt gcgaccatgg ctatcggtga
    16201 agctggagcg actaacgcag ctctctttgc cctccgtctc ctctctgtag aagataagtc
    16261 cattgcggat gcacttgcca actttgctga agaacaagga aaaatcgcag aggagtcgtc
    16321 aaatgagctc atctaaaaca atcggaatta tcggtggcgg tcaactgggt cagatgatgg
    16381 ccatttctgc tatctacatg ggccacaagg ttatcgcgct ggatcctgcg gcggattgcc
    16441 cggtctctcg tgtggcggaa atcattgtgg caccttataa cgatgtagac gccctccgtc
    16501 agttggcaga ccgttgcgat gtcctcactt acgagtttga aaatgtcgac gctgacggtt
    16561 tggatgccgt tatcaaggat ggacaactcc ctcaagggac agacctgctc cgcatttcgc
    16621 aaaatcgtat ttttgaaaag gactttttgt caaacaaggc tcaagtcact gtggcaccct
    16681 acaaggtcgt gacttctagc ctagacttgg cagatatcga cttgtcgaaa aactatgtcc
    16741 tcaagactgc gactggtggc tacgatggtc atggacaaaa ggttattcgt tcagaagtag
    16801 acttggaagc agcctatgcg ctagcagaat cagcagactg cgtcttggaa gaatttgtca
    16861 actttgccct tgagatttct gtcatcgtgt caggaaatgg caaggaggtg acgtttttcc
    16921 cagttcagga aaatatccac cgcaacaata tcctgtctaa gaccatcgta ccagcccgca
    16981 tttctgaaag tctagtagac aaggctaaag ctatggcagt gcgaatcgca gaacaactca
    17041 acttgtctgg aactctctgt gtggaaatgt ttgcgactga tgatgacgtt attgtcaatg
    17101 aaatcgcccc acgaccacat aactctgggc actattctat tgaagcctgt gatttctctc
    17161 agtttgacac ccatattctc ggtgttctcg gagcaccatt accagtcatc aaactccatg
    17221 cgccagccgt tatgctcaat gtcctaggtc aacacgtcga ggctgctgaa aagtatgtcg
    17281 cagaaaatcc aagcgcccac ctccacatgt atggtaaaat agaagcaaag cataatcgta
    17341 agatgggaca tgtgaccttg tttagtgatg taccggatag tgtggatgag cttggggaag
    17401 ggattgattt ttaggacaag tctatgatac aaattatcgt taatacattt attgaaaagg
    17461 ataagactgg agcagttgtt gaagtgttgt atgccagtgc tgaccaagat aaggtacaag
    17521 ctaaatatga agaactagct gcacaatacc ccgaaaatta tttagctatc tatgatgtac
    17581 cgctggatac ggatttgaat acactagatc attacccgtc tgtgtttatt ggaaaagagg
    17641 agtttgagta gaaatcttgg tttacctaga tagcttattc ccaacagctt aagaagaaag
    17701 gaaaaattaa cacatgatca accgttactc tcgccctgag atggcgaata tttggagtga
    17761 agaaaataaa taccgtgctt ggcttgaggt ggaaatcctc tctgacgagg catgggctga
    17821 gttgggggaa atccctaagg aagatgtggc tttgattcgc aagaaggcgg actttgacat
    17881 cgaccgtatt ttggaaattg agcaggagac gcgccacgat gtggtggctt tcacgcgtgc
    17941 ggtttctgag actcttggtg aagagcgcaa gtgggttcac tatgggttaa cttctaccga
    18001 cgtggtggat actgcttatg gttacctcta caagcaggcc aacgacatca tccgtcgtga
    18061 ccttgaaaac ttcactaata tcatcgctga caaggccaag gagcacaagt tcaccatcat
    18121 gatggggcgt actcatggtg tgcacgctga gccgacaacc tttggtctta aattggcaac
    18181 ttggtacagc gaaatgaaac gcaatatcga gcgcttcgag catgcggctg ctggtgtaga
    18241 agctggtaag atttctggtg cggttgggaa ctttgccaat atcccaccat ttgtagagga
    18301 gtatgtctgc gataaacttg gcatccgtgc ccaagaaatc tctacacaag tccttcctcg
    18361 tgaccttcac gctgagtact ttgcggttct tgccagcatt gcgacttcaa tcgaacgtat
    18421 ggcgactgag attcgtggtc tacaaaaatc tgagcaacgc gaagtagaag agttctttgc
    18481 taaagggcaa aaagggtctt cagcaatgcc tcacaaacgc aacccaatcg gttctgaaaa
    18541 tatgactggt ctggcgcgtg tcattcgtgg tcacatgatt acggcttatg aaaacgtcgc
    18601 tctctggcac gaacgcgata tttctcactc atcagctgag cgtatcatca caccagatac
    18661 gaccattttg attgactaca tgctcaaccg ttttggaaat atcgtcaaga acttgacagt
    18721 cttcccagaa aatatgatcc gaaacatgaa ctcgactttt ggtcttatct ttagccaacg
    18781 ggctatgttg acattgattg aaaaaggcat gacccgtgag caagcctatg acttggtgca
    18841 accaaaaaca gcctactctt gggacaacca agtagacttt aaaccacttc ttgaggcaga
    18901 ttcagaagta acatcacgtc tcacacaaga agaaatcgat gaaatcttca acccagttta
    18961 ttacaccaaa cgagtggatg atatctttga acgtcttgga ctaggtgatt aattaaaaaa
    19021 taaacagcga gcttcaatct cgctgtttat tttttatcga aaagacttag tcttcttttc
    19081 ttttagtgag tccataggct gctagtgtgg acatgagtcc tgcgactact agtcctgcag
    19141 aatcgtgagt tcctgtttca ggaagttttt tctctgttac cacaggagct ggatcttgag
    19201 gaagaacttt gctttcctca gcaggagcag ttgatggagc tggttggctt gggatttcta
    19261 gttttggttt ttcttcagca atagcggctt gtccgttttc atcgcctaca tgtgttacca
    19321 tagttccgac ttcgactatt tgagtaacgg cttcctgtgc tacgacacta tttacaagtg
    19381 ttttcacttc cttaccatcg gcagaagtgc tcacagagta gaagttgcta cgatgtccat
    19441 tgacgccctt agtaatgact tgtgtttttc ctttgagtaa gagtggattt tcacgagtca
    19501 ctgtggtaaa tggaatgtct tcttcttgga tatccagtct aggttttacc tcagtagttg
    19561 gtgcaagacc actttcatca cccttgtgag ttacaggagc gccaacttca accacttggt
    19621 ttataacttc tttggttacc tggctatcaa ggactgtttc tgttgttttt ccattttcag
    19681 tgagtacaga gatgtaatga gttcgttcac ctttgactcc tgctgtgata atattttcct
    19741 gaccggctgg gaggttagga ttttctttct tgataacttc aaatggaatt tcttcagttc
    19801 ttgtgatgag ttctggtctg gtttcaacat tggcagccac ttcattttca tctaggcttc
    19861 ctgaatgagt tacagctggt ttgaggcctt gaagagcggc ttttaggttg gctacaagtg
    19921 tgtcaagctc agcttgttta ttacggttga ggttgtaatt tagagctgtt ttagctgcgt
    19981 caagggcctc aagactttct ttactatatc cttctaagtt tgtaggaatt ttagctaatt
    20041 cttcgcggag agcattataa ttagcacgga agtagtcttt gttgtggtct gcaaaggcag
    20101 tcatgagttc aaagatttcc tcttccttgt attcagcgct tggtctatct gcccagattg
    20161 aaagcatact tccgactgtt ggaagatcta cttcaggata tttggtagaa gctagttgat
    20221 tgaatggtgt ttttccagta ttctcaatag ctttcttgag gaaaccacca ccatcttctg
    20281 gtttttgacc aagaatgtag taccagtcac cgttggtatt caagaattta tagcctttgc
    20341 ttgctaggta ttgaggtgat gcgaggttat atccccacca gcctttagac cagtaagaaa
    20401 tcaagacatc tttgtcaaac tgaacatcgt ccttgtcttc atagtagaag ccatcgttga
    20461 aggccattgg ttgaagccct ctttctttgg ccatagctgc gagggtgttg gcatattcgg
    20521 caaatttgcc atagagttga taccacttga ggtagtacca gccttgggca ctagtcgcat
    20581 cgttggcgta ttcgtcagta ccaaagttga aaatctttgt tttacctgca aagaagtcca
    20641 tgtatttacc gatgagggct tttacaaagt tcatcgcttc ttcgtttttc aagtccatag
    20701 ttgtttttga aactttatca aagtgggctt gaggattttt aatacctaat ttttccatgg
    20761 caaccagcat agcatccatg tgacctggac tgttaatagc tgggatgaga cctatgtcct
    20821 tagatttagc gtattcaatt agctctgtca cttctgcctg tgttagtgca gtaccgtttg
    20881 gatcgtcgta gtaagcttta gttccttcga taatagcttt tttaacgtca tcactagcat
    20941 aggtttttcc gttggcagta atggtcatat catcgagtag aaagcgaagt ccgtcatttc
    21001 ctagaaggag atggacatca gaatatccga gctcactggc cttgtctacg atgcgtttga
    21061 gctggttcag agtaaagtat ttgcgtccag catcgattga gattatcttg tttttggcaa
    21121 gtttttcaac ctcacgttta gcttcttctt ctttttgagc ttcaggcgtg agggtcaagt
    21181 tgttgacagt ttcttgaagt ttagcaatgg cttgatcaat cgtatcttgt tgggcacggc
    21241 taaggttgct atcgagagag cgaatagctt tttcagcttc ttttacggcc gtgacgcttt
    21301 ctgcagtata acggttcagg tcttttggta cctcgttaag tgcttgctct gcagattcat
    21361 aatcagctgc gaagtattca gcgttggcat ttgcaaaatg acgcatgagt ttgaagaggc
    21421 gtgatggtga ataacgtgca gatggagtgt cagcccaagc agctaccata ccaccgatga
    21481 ttgggatatc agctccttct gtttttggta cagaagtgat tggtgtgttt ttaataccat
    21541 tgagcccctg atcgagattg taccagcctt ggccatcagc gtttcgtcca agaacgtagt
    21601 accaagcatc attggtatta aggatttggt gacctttttc agctagtagt ttagaagaag
    21661 cgacatcgta gcctccccaa ccaccagtcc acatagaaac gatgatgtct ttgtcaaaac
    21721 taccaaagct tgtgtcgcta ttgtagtaga taccgtcgtt aaaggccatt ggtttgagac
    21781 cgtgcgattt tacaatacga gcgaggtcat tggcgtaggc aataaatttt tcatagcctt
    21841 ttacagggta gccttcgttt ggatagtatt tatcagcttg aagcacactc caacctttag
    21901 catctgtcgc atcattggca tattcatcaa gtccgatgtt gaagatttca gtctttttcg
    21961 cgaaataagc agcatacttg tcgataaggg cttttgtaaa agcgacagct tgttcgttgt
    22021 caagatcgac agtacgggct gattccttcc caaaatagct aaagttaggg ttttggattc
    22081 ccaattcttt catggcattg agaatcgcat ccatgtgccc aggactattt actgtcggaa
    22141 tgagaccgat acctttatct ttggcatagt taatcagatc tgtcatttga ctttctgtta
    22201 agtgattgcc gtttggatcg tcgtaataat catttgtacc tttttcaatg gcgcgtttga
    22261 catcgtcact ggcataggtc ttgccgttag ctgtgatgct catatcgtcc aacatgaaac
    22321 ggagtccatc atttccgact aataggtgta aatcagtgta gccataatgt ttcgctttat
    22381 cgatgatttc cttgagctgt tctggtgaga aatatttacg tccagcatca atagaaacaa
    22441 ttttcttttt cgctagtttt tcatttacag ttgcagcacg ttcctttcct gcctctgttt
    22501 ccggtttgtc agcctctgct ttcgcttcat cttttttagc tggtttatcc ttgtcagtct
    22561 tgtctgtatt tgactcttta gaatcaacct ctttcgcttc ttccttttta gggctagctt
    22621 cttctgcctt tttattagca gtttcttttt cagcagaagt tggagttacc acgtctgctt
    22681 tatcactagg agttgaacta acttcctctt gtggtttttc ttctgttttt ggaagactag
    22741 ctaccttatc agtagctgga gtttctgttt ctacagtttt tggagcttct ggttgaagct
    22801 ctgctttagg tgtttcctca gtccgatttt cggatgattg aggggaatca gaaaccgtat
    22861 ggatggtcgg ttggttttct gtagtagtag gagtaactcc atcggctgca acagtctgtg
    22921 cttggaaggc aaatccaatt agaacagaag ctgctcctac agcgtattta cgaatagaaa
    22981 aacgctgttg tttttcatgt ttcattgcaa aacctcctga ttgcattgtt atattgatag
    23041 cgattatata aatcaacgcc tttattttat ttcttatatt aacgagagtc aagaggagat
    23101 gacaaaaaac tataataagt ataaaaaaat ataaaattta aacttaagat ttcagattgg
    23161 tcgaaaatac atatatatat ctagtataat ttttggttct atttctataa aatattccac
    23221 aaattataga atcttccaaa aataggtaag cgctaccttt ttggtgtggt ataataagca
    23281 tagaaaaagc ccgagcgatt aggctcaggc tttcttctta gtgatcacgg tcacatgaga
    23341 tgaattcaat cttgtagtaa tcagatcgtt tgtaagtttc actgtattct aaaacttggc
    23401 cagttgattc gagtttggtg attttagttt gtaggacagt agggaattgt tcatcgactc
    23461 cgaggactga agccgcatgt tctggagttg gaaagactat ttcgttgatt tcttcaaagt
    23521 gttcatcatt catgtgaatg tggtagtcta acttgaaacg attatagata gaactatagt
    23581 attcaaggtt tggataattt gcgttgatat attgttctgg gatgtaggat gtatggtaga
    23641 tataaacgac accgtttgat tcgcggatac gttcaatctt gtagtagaat tgatcgccgc
    23701 gtagacccaa tttttccaag taaacaagct tgtttccgcg ttcaattgaa agaacagtta
    23761 ccttatcatc tttagcattg aagagttcaa tatctgaaaa ctctacaagc ttgtgtttgc
    23821 gtgcacgtga aacgaaggtt ccttttcctt gttggcggac aatatagcca tctttggcaa
    23881 ggtcgtttaa ggcgcgaaca actgtgatag agctgacatc gtacattgaa atgagttctg
    23941 cttcagtgta aaatttatct ccactgctaa actgcccaga gatgatttta ttttttaatt
    24001 cgtcttttat gtattgatat ttgggaattg ccatattttt acctctattt tccttctcca
    24061 tagaaaattt taccataaaa gcgaaaaaaa tagtagtctt ttgaataaaa aattagaata
    24121 atagtttgaa aaattaagcg atatagggat tgctcatatt ttatcaatgt attctataca
    24181 aaattatttt aggtcctata ttccgaattt aaagagcgtt tgaaatgggt ctaaaaatgt
    24241 ttgaaactaa ttgaatgtgt gtataatagt aaaaatgcag taaatatccc gacaatttct
    24301 attgacaatt caaacagatt ggtttataat taatataaca acaaatgaaa gcgcaaactt
    24361 tcgcggtcgg aaggtagttt tatgacacga tttgagatac gagatgattt ctatctcgat
    24421 ggaaaatcat ttaagatttt atctggtgcc attcattatt ttagggttcc tccagaggat
    24481 tggtatcatt cgctctataa cttgaaggct cttggtttta atacggtaga gacttatatt
    24541 gcttggaatt tacacgagcc tcgtgaaggt gagtttcatt ttgacggtga tctggattta
    24601 gagaaatttc tccaaatagc gcaggatttg ggtctctacg caattgtgcg tccgtctcca
    24661 tttatctgtg cggaatggga attcggtggc ttaccagctt ggctcttgac caagaacatg
    24721 cgaattcgct catccgaccc agcatatatc gaggcagttg gtcgctacta tgatcagtta
    24781 ttgccaagac tggtgcctcg tttgttggac aatggtggca atattctcat gatgcaggtt
    24841 gaaaatgagt atggttctta cggagaagat aaggcttacc tgagagcgat tcgacagcta
    24901 atggaagagc gtggcgtaac ctgtcctctc tttacatcag atggtccatg gcgagctact
    24961 ctgaaagctg gaaccttaat tgaagaggac ctctttgtaa caggaaactt tggttctaag
    25021 gcaccttaca acttttcgca gatgcaggaa ttctttgatg aacatggtaa gaaatggcca
    25081 ctcatgtgta tggagttctg ggatggttgg tttaatcgct ggaaagaacc gattatcaca
    25141 cgggatccta aggaattggc agatgcagtt cgagaggttt tggaacaagg ctctatcaat
    25201 ctttacatgt tccacggtgg tacaaacttt ggtttcatga atggttgctc ggctcgagga
    25261 actttggacc tgccacaagt tacgtcttat gattacgatg cccttctgga tgaagaagga
    25321 aatccaactg ctaaatatct tgcagtcaag aagatgatgg caacacattt ttcagagtat
    25381 ccgcagttgg aaccactcta caaagagagt atggagttgg atgctattcc actagttgaa
    25441 aaagtttctt tgtttgaaac cttagatagc ttgtcaagtc ctgtagaaag tctctatcct
    25501 caaaagatgg aggagctggg acaaagttat ggctacctac tttatcgaac agaaacaaac
    25561 tgggatgcag aagaagaaag acttcgtatc attgatggtc gagatagggc ccagctgtat
    25621 gtcgatggtc agtgggttaa aactcaatat cagacagaga ttggggaaga tattttttat
    25681 caaggtaaaa agaaagggct atctaggtta gatatcttga tagaaaatat ggggcgtgtc
    25741 aactatgggc ataagttctt agcggatacg caacgtaagg gaattcggac aggggtctgt
    25801 aaggatctgc atttcttact aaactggaaa cactatccac ttccactaga caatcctgag
    25861 aaaattgatt tttcaaaagg atggactcaa ggacaaccag ccttttacgc ttatgacttt
    25921 acagtcgaag agccaaaaga tacttaccta gacttgtctg agtttggtaa gggagttgcc
    25981 tttgtcaatg ggcagaatct aggacgtttt tggaacgttg gcccaactct ctcactttat
    26041 atccctcata gctatctcaa ggaaggtgcc aaccgcatca ttatctttga aacagaaggt
    26101 caatataaag aagagattca tttaactcgt aaacctacac taaaacatat aaagggggaa
    26161 aacttatgac aattgtagga tgccgtattg atggacgttt gatccacgga caagtagcca
    26221 atctttgggc tggaaaacta aatgtttcac gcattatggt tgtagacgac gaagttgtca
    26281 acaacgatat tgaaaagagt ggtttgaaac ttgcgacacc accaggtgtg aaattgagta
    26341 ttttgccagt tgagaaagct gcagccaata ttcttgctgg taaatacgat agccaacgtc
    26401 tctttatcgt ggctcgtaaa ccagaccgct tccttggctt ggtagaagca ggtgtaccac
    26461 ttgaaaccct taatgttggg aatatgtctc aaacaccaga aactcgttct attacacgtt
    26521 ctatcaacgt agtagacaag gatgtggaag acttccacaa actggcagaa aaaggtgtta
    26581 aacttactgc tcagatggtt ccaaatgatc caatttcaga ctttttgagc ttattaaaat
    26641 aggaaaaaaa tttttaggag gtcattgtta tgatacaatg gtggcaaatt ttacttctca
    26701 ctttgtactc agcttatcaa atctgtgatg agttgacgat cgtttcatct gcaggttccc
    26761 ctgtatttgc tggtttcatt actggtttaa tcatgggaga tgtgactact ggtttactta
    26821 tcggtggtaa cttgcaactg ttcgttcttg gggttggtac cttcggtggt gcttctcgta
    26881 tcgacgcaac ttctggtgcg gttcttgcga cagccttctc tgtttcacaa ggaattgatg
    26941 caccgcttgc cattactaca atcgctgtac cagtagcagc tctcttgact tacttcgacg
    27001 ttcttggtcg tatgactact accttcttcg ctcaccgtgt ggatgctgca atcgaacgct
    27061 ttgactataa aggtattgaa cgcaactact tgcttggtgc gattccgtgg gctctatctc
    27121 gtgcccttcc agtcttcttt gcccttgctt ttggtggtgc ctttgtacaa tcagtagtag
    27181 acttcgttga agcctacaaa tgggttgcag atggcttgac acttgcagga cgtatgcttc
    27241 caggtcttgg atttgcaatc ttgcttcgtt accttccagt taaacgtaac cttcactacc
    27301 ttgctatggg atttggtttg acagctatgt tgactgttct ttactcatat gtaacaggtc
    27361 ttggtggcgc tgttgctggt atcgtaggta ctcttcctgc tgaagttgct gaaaaaattg
    27421 gtttcgtgaa caacttcaaa ggtttgtcta tgattggtat ttctatcgta ggtattttcc
    27481 ttgcagtgct tcacttcaaa aatagccaaa aagtagctgt agcagcacct tctacaccat
    27541 cagaaagtgg ggaaatcgaa gatgacgaat tctaattaca aacttacaaa agaagatttt
    27601 aatcaaatca acaaacgtag cttgtttact ttccaattag gttggaacta cgaacgtatg
    27661 caagcttctg gttaccttta catgatcttg cctcagttgc gtaaaatgta tggtgatgga
    27721 actcctgaat tgaaagaaat gatgaaagtt catactcaat tcttcaatac ttcaccattc
    27781 ttccatacca ttatcgctgg ttttgacctt gccatggaag aaaaagatgg tgtaggttca
    27841 aaagacgctg ttaacggtat caagacaggt ttgatgggac cattcgctcc tcttggggat
    27901 acaatctttg gttcacttgt acctgctatc atggggtcag tcgcagcaac tatggctatc
    27961 gctggccaac cttgggggat cttcctttgg attgcagttg cagtagcgta tgacatcttc
    28021 cgttggaaac agttggaatt tgcttacaaa gaaggggtta accttatcaa caacatgcaa
    28081 agtaccttga cagctttgat tgacgctgca tctgtacttg gtgtcttcat gatgggtgct
    28141 cttgtagcaa cagtgattaa ctttgaaatt tcttacaagt tgccaatcgg tgaaaagatg
    28201 attgatttcc aagacatctt gaaccaaatc ttcccacgtt tgcttccagc aatctttact
    28261 gcctttatct tctggttgct tggtaagaaa ggtatgaact ctactaaagc tatcggtatt
    28321 attatcgtac ttgctttggc tctttctgcc cttggtcact ttgcacttgg aatgtaattc
    28381 cttatgacta aatcattaat tttggtgagc catggtcgct tctgtgagga gcttagaggt
    28441 agcacagaaa tgattatggg cccacaagac aacatttaca cagtagctct tcttccagaa
    28501 gatggcccag aagaatttac tgctaaattt gaagctgtta ttgaaggatt ggatgatttc
    28561 ctagtttttg cggatcttct cggtgggaca ccttgtaatg tggtgagtcg cttgatcatg
    28621 gaaggtcgtg atattgacct ttacgcaggg atgaatcttc caatggtgat tgaatttatc
    28681 aatgcgagcc ttacaggcgc agatgcggac tacaagagcc gtgctgcaga aagcattgtg
    28741 aaagttaatg acctgttagc gggcttcgat gatgacgaag atgaataata ctcttcgaaa
    28801 atctcttcaa actacgtcaa cgtcgcctta ccgtaggtat atgttactga cttcgtcagt
    28861 cttatccggc aacctcaaaa cggtgttttg agctgacttc gtcagtctta tccggcaacc
    28921 tcaaagcagt gctttgagca gcctgcggct agtttcctac agattttagt tggaactcga
    28981 ttcaattcat gtgacaacgt gaaaatcgtt agagcatttt atatagaata tacatgggaa
    29041 tggagcttac tcccattcct atatttaata gaaaaagagg aactcaatgc tacattatac
    29101 aaaagaagac ttgctcgaat tgggtgcaga aatcactacg cgtgaaatct accaacagcc
    29161 tgatgtatgg agagaagctt ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt
    29221 cctacaagaa atcgctgata aacatgacta tattaaggtt atcttgacag gtgctgggac
    29281 ttctgcttat gtgggagaca ccttgctacc ttactttaag gaagtctatg acgaacgcaa
    29341 atggaatttc aatgctattg cgacaacaga tatcgttgcc aatccagcaa cctatttgaa
    29401 aaaagatgtg gcaactatcc ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt
    29461 ggcgactgtt gatttggcca aatccttggt ggatgagctt tatcaagtga cgattacttg
    29521 tgcaacagat ggtaaattgg ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt
    29581 gcaaccagct gtctctaatg atgctggatt tgccatgact tctagcttta cgtctatgat
    29641 gttgacagct ctcttggtct ttgatcctac agaatttgct gttaagtctg aacgttttga
    29701 agttgtatct agtcttgccc gtaaagtttt agacaaggca gaagatgtca aagagctcgt
    29761 tgatttagac tttaaccgtg tcatctatct aggcgctggt cctttctttg gacttgctca
    29821 tgaagctcag ctcaagattt tggaattaac tgctggtcaa gttgcgacca tgtatgaaag
    29881 cccagttggc ttccgtcacg gtccaaaatc tcttatcaac gacaatacag ttgttttggt
    29941 ctttggtaca acgacagact acactcgtaa gtacgacttg gacttggttc gtgaagttgc
    30001 tggtgaccag attgctcgtc gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa
    30061 tgtcaaagaa gtggcccttg gttgtggcgg tgtcttgaat gatatttacc gtgtcttccc
    30121 ttacatcgtt tatgcccaac tctttgccct attgacttca ctcaaggtag aaaataaacc
    30181 agatacaccg tctcctacag gtacagtaaa ccgtgtagta caaggtgtca taattcacga
    30241 atattaaaag taagacagtg tttatgaatt cttgacaaga ggatttgtaa attatcagat
    30301 aaaccataga ttgtcagtac gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg
    30361 agaacagaat gaaagcatac acagagcgtg tatttggaaa tgttgagggc gaggatgtct
    30421 tggcctatcg atttgagaca gacggtggct accaacttga ggttatgact tatggcgcga
    30481 ccatcttgcg ctatgtcgca cctgacaagg ctggaaattt tgccaatgtt atcttgggat
    30541 ttgatgactt tgatagttat gtaggcaata gtcccaagca tggagcaagt gtaggtcctg
    30601 tagcgggtcg tattgcaggt gcgacctttg agctcaatgg taagacctat gaccttgagg
    30661 ttaataatgc tagcaactgt aatcacagtg gttcaactgg ttgggattcc agcttgtttg
    30721 aagttgaaga agtaagcgat catggcttga ctctctacac agaacgtaca gatgggacag
    30781 gagggttccc tggaaatctc aagatttgga tcagttatca cttggaagaa actggtgcct
    30841 atgaaattag ctacaaggta acgaccgatc aggatacgct ggtcaatcca accaaccaca
    30901 gctatttcaa cttgtctggt gatttcacgc agacgattga ccgtcatgtc ttccaactaa
    30961 acacagaggg catttactca atcactcctg acggtgttcc tgccaaaact ccagaagcca
    31021 accgtgatgt ggtcaaacac atctacaatg gtaccttgtt gaaggatatc tttgcagaag
    31081 aagatgagca aatccagctg gcatcaggtt tggatcaccc atttgccctt cctgtaggcc
    31141 atgacaatgc tggattcctt tatgaccaaa attcaggtcg cttcctgctt ttcaagacag
    31201 aagctccttg ctttgtggtc tacacagcaa actttgtgga tgaaagtgtc atcataggag
    31261 gtcagccaat gctacagcac aatgggattg ctcttgaagc gcaagcttta ccagatgcca
    31321 ttcacagtga ccttaaaggc caagtcattc ttaaagctgg tcaaaccttc accagtaaga
    31381 cacgttatga acttgttgtg aaataaaaaa gctggtcaaa aagtctttaa aattaaaata
    31441 acgcatattg tcaggtgatg aaaagtttga tactatgcgt tttattatga aatgatttac
    31501 tttatcttat cctgaaatgg tgttattttt gagttatctg gcttgacttt cttgatggaa
    31561 attatataat agttgtaata acaataatta caacgagaaa agaggaccat ttatgaccta
    31621 tgaatacaag agtcacattt atttggcaga gacagtttta aatgtaaagg atttggccag
    31681 tcaaacagcc ttttatcagc aagttattgg tttagaaatc ttatctcaaa ctgagacaga
    31741 gtccattcta ggccttggtg gaaaagtctt ggtacagctg attcaagcac aagagagcgg
    31801 agaagtgagg gaacattatg gtctttacca tttggccatt ctcttgccca cacgcaaggc
    31861 tttggctgat gtcttgaaac acctgacaga tttacagatt cctcttgtcg gcggtgcaga
    31921 ccatggttac agtgaagcta tttacttgga agatttggag ggaaatggca ttgaactcta
    31981 tcgagataag ccagtttcca catgggatat tcgagaagat ggacgcatta tcggagtgac
    32041 ggaggctctt gcggcgcagg acatttatga gttgggggaa agagtagagc cctttatcct
    32101 ggcagaaggt acaagaatgg ggcatattca tctttccgtc aaggatagtc gaaagtccag
    32161 ccagttttat caaaaggtgt tagggctaga ggataaattc agtgtgccta gcgctagttg
    32221 gattgcggct ggagattacc atcatcattt agcagttaac gaatggggag gaaaaggtct
    32281 ggcttcgcgt aagcaaggct taccaggttt agcctactat gtcatcgaag tcgcacataa
    32341 agaagaactg ttaacgattg tccaacgagc acaagaagtt gacgcaccaa tcaaatggat
    32401 gacatcgagc caattggaaa tcacagactc agatggcatc gtgacccgta ttcgtttagc
    32461 aaggtaaaat taggaatttc taataagtta taagtattgc tagtttgctt tttgaacggt
    32521 ctttggtaac agaactgcgt gagctggatg ggtgagaatt ttgacaaaga agctgattag
    32581 agatataatg aagaaaaatc gagcaaggaa aaagaaatga caaattcaaa gtatattact
    32641 tgtttgaaac gttcagaggg ccagttgtgt gggattcaaa agatgattga aggagatcgt
    32701 gactgtgctg atattgtgac gcaactgaca gcagtgagat ctagtgtaga gcgcgtgatt
    32761 gagatgataa ttaccgaaaa tcttactgaa tgtatcaatc agccactaga tgattctgaa
    32821 gctcaaaagg aacgcctaga aaaggctatc cgatacttga ttaaacggaa ataaatgaat
    32881 gttttgagac gatatgtgca aaggtctatt aactattaga atagtttaat gtgagtcaaa
    32941 agaagttgta aaaaatcttt aaaattaaaa aaacgcatag tatcaggtgt tgaatgtact
    33001 gacccccaaa agttagattt tttctgtcta acttttgggg gtcagttcat aagaaccttg
    33061 gtaatatgcg ttttattatg tagaaactta tactcttcga aaatctcttc aaaccacatc
    33121 agcttcacct tgccgtagat atggttactg acttcgtcag ttctatccac aacctcaaaa
    33181 cagtgttttg agctgacttc gtcagttcca tccacaacct taaaacagtg ttttgagcag
    33241 cctgcggcta acttcctagt ttgcacttta attttcattg agtattactt catcttctca
    33301 tgaaattgag tttttgccca gctcctcttg attattctac ttgaccgggc caagtattca
    33361 taccaccttc tacgttggta acggtgaggc cttgggagct gagaaattgg caggtagatg
    33421 cagagcggac tcctccttga caaataacat agtattcatg gtcaggtttg agttctttgt
    33481 agccttgctc taaggtactt aatggaagat ttttggcacc tggtgcatgt cctgcttgga
    33541 attcatgtgc ttcacggaca tcgataagtt ctagattttc attttagtat tttccataaa
    33601 agtcagccat gctgatacta gtttccatat tctactcctt ctgggttagc cattttgtat
    33661 agtgaataag cgccgtcaag gttttggacg gtaaatcctg cttgcttgag gataggctct
    33721 gcgatatagc tgcgcaaacc actgtggcag ctgacgatgt aggcttgttt tttgtccagt
    33781 tcatcagctt cctccttgac actttgtcag tttttgatac aatagtacaa aattagagga
    33841 ggtgggctat gattcagaaa catgcgattc ccattttaga gtttgatgat aatcctcagg
    33901 cggttatcat gcccaatcac gaggggttgg atttgcagtt gccaaagaag tgtgtctatg
    33961 cttttttagg tgaggagatt gaccgctatg cgagggaagt aggggcgaac tgtgttggcg
    34021 aattcgtttc tgctaccaag acctatccag tctatgtcat caactacaag ggtgaggagg
    34081 tctgtctggc tcaggctcct gttggctccg ctccagcagc ccagtttatg gattggttga
    34141 ttggctatgg tgtggagcag attatctcta ctgggacctg tggtgtccta gctgatatag
    34201 aggaaaatgc ctttctagtc cctgttcgcg ctttgcgaga tgagggagcc agttaccact
    34261 atgtggcacc ttgtcgttat atggaaatgc agccagaggc tattgctgct attgaggaag
    34321 ttttggaaga cagagggatt ccttatgaag aagtcatgac ctggacgaca gacggttttt
    34381 accgagaaac ggctgaaaag gtggcttatc gtaaggaaga aggctgtgct gttgtggaga
    34441 tggagtgttc tgctcttgcg gcagtagctc aattgcgtgg ggttctctgg ggtgaattgt
    34501 tgttcacagc agattctcta gcggacttgg accagtacga cagtcgtgac tggggctcgg
    34561 aagcttttaa taaggcgcta gaactgagtt tagcaagtgt tcaccacctt tagttgtaca
    34621 ggcaaaggat ttgttttatc ataaaatgtc tagctcatac ttttcaaaaa tatgtttaaa
    34681 cgaggtcacc ttcctcttgt cctaggcatg ttgaggttgg gaaaaatctt taaaatcaga
    34741 aaaacgtatc atatcaggtg atgaaaattt tgatactatg cgttttatgt tggtaagatt
    34801 tagagtgaga tgaaatgata ctcttcgaaa atctcttcaa accaggtcag cttcaccttg
    34861 ccgtaggtat atgttactga cttcgtcagt cttatccggc aacctcaaaa cggtgttttg
    34921 agctgacttc gtcagttcta tccacaacct caaaacagtg ttttgagcaa cctgtgacta
    34981 gctttctaag cgatgccttg gttctcattg cctataatca aaaagagaaa ttttctcctg
    35041 aaaagcatat agagtagctg gcgttaaaag ctcctgtctt gcttttttga cctatagtca
    35101 catctatcaa gtattgttct tgcctaagct atcaataaaa aggtggcatt ttttaggctt
    35161 ggtgttagtg aattttgcct tatcctatct aagtcatttc gagcttttta tggtacaatg
    35221 gaaacatgtt attcaaatta tctaaggaaa aaatagagct aggcttatct cgtttatcgc
    35281 cagcccgtcg tatttttttg agttttgcct tggtcatttt actaggctct cttcttttga
    35341 gcttgccctt tgtccaagtt gaaagctcac gagcgactta ttttgatcat cttttcactg
    35401 ctgtctctgc agtctgtgtg acaggtctct caacccttcc agtagctcac acctataata
    35461 tctggggcca aataatctgt ttgctcttga ttcagatcgg tggtctaggg ctcatgactt
    35521 ttattggggt tttctatatc cagagcaagc aaaagcttag tcttcgtagc cgtgcaacta
    35581 ttcaggatag ttttagttat ggagaaactc gatctttgag aaagtttgtc tattctattt
    35641 ttctcacgac ctttttggtt gagagcttgg gagctatttt gcttagtttt cgccttattc
    35701 ctcaacttgg ctggggacgt ggtcttttta gttccatttt tctagcgatc tcagccttct
    35761 gtaatgccgg ttttgataat ttagggagca ccagtttatt tgcttttcag accgatttac
    35821 tggtcaatct ggtgattgca ggcttgatta ttacaggcgg ccttggtttt atggtctggt
    35881 ttgatttggc tggtcatgta ggaagaaaga aaaaaggacg tctgcacttt catacgaagc
    35941 ttgtactatt gttgactata ggtttgttgt tatttggaac ggcaactact ctctttcttg
    36001 agtggaacaa tgctggaacg attggcaatc tccctgttgc cgataaggtt ttagttagct
    36061 tttttcaaac agtgacgatg cgaacagctg gcttttctac gatagattat actcaggctc
    36121 atcctgtgac tcttttgatt tatatcttac agatgtttct aggtggggca cctggaggaa
    36181 cagctggggg actcaagatt acgacatttt ttgtcctctt ggtctttgca cgaagtgagc
    36241 ttctaggctt gcctcatgcc aatgttgcga gacgaacgat tgcgtcgcga acggttcaaa
    36301 aatcctttag tgtctttatt atctttttga tgagcttctt gataggattg attctgctag
    36361 ggataacagc caaaggcaat cctcccttta tccacctcat atttgaaacc atttcagctc
    36421 ttagtacagt tggtgtaacg gcaaatctga ctcctgacct tgggaaattg gctctcagtg
    36481 ttatcatgcc acttatgttt atgggacgaa ttggtccctt gaccttgttt gttagcttgg
    36541 cagattacca tccagaaaag aaagatatga ttcactatat gaaagcagat attagtattg
    36601 gttaagaaag gaaagagcat gtcagatcgt acgattggaa ttttgggctt gggaattttt
    36661 gggagcagtg tcctagctgc cctagccaag caggatatga atattatcgc tattgatgac
    36721 cacgcagagc gcatcaatca gtttgagcca gttttggcgc gtggagtgat tggtgacatc
    36781 acagatgaag aattattgag atcagcaggg attgatacct gcgataccgt tgtagtcgcg
    36841 acaggtgaaa atctggagtc gagtgtgctt gcggttatgc actgtaagag tttgggggta
    36901 ccgactgtta ttgctaaggt caaaagtcag accgctaaga aagtgctaga aaagattgga
    36961 gctgactcgg ttatctcgcc agagtatgaa atggggcagt ctctagcaca gaccattctt
    37021 ttccataata gtgttgatgt ctttcagttg gataaaaatg tgtctatcgt ggagatgaaa
    37081 attcctcagt cttgggcagg tcaaagtctg agtaaattag acctccgtgg caaatacaat
    37141 ctgaatattt tgggtttccg agagcaggaa aattccccat tggatgttga atttggacca
    37201 gatgacctct tgaaagcaga tacctatatt ttggcagtca tcaacaacca gtatttggat
    37261 accctagtag cattgaattc gtaaagaggg atgacccctc ttttttgatg cccaagatgg
    37321 caaatagaga cagaagcccc ttgtcttcta gtaaaagttc ttcaaaggct ggactttatg
    37381 gtaaaataga aggaagtgac aagagagagt aatactcaat gaaaatcaaa gatcaaacta
    37441 ggaaactagc tgcgggctgc tcaaaacact gttttgaggt tgtggataga actgacgaag
    37501 tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt aacatctata
    37561 cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa gagtataaga aaaaatcagt
    37621 cccctaaagg agcagattat gaagttattg tctatcgcca tttctagcta taatgcagca
    37681 gcctatcttc attactgtgt ggagtcgcta gtgattggtg gtgagcaagt tgggattttg
    37741 attatcaatg acgggtctca ggatcagact caggaaatcg ctgagtgttt agctagcaag
    37801 tatcctaata tcgttagagc catctatcag gaaaataaat gccatggcgg tgcggtcaat
    37861 cgtggcttgg cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg
    37921 gatcctcgtg cctacttgaa aattcttgaa accttgcagg aacttgagag caaaggtcaa
    37981 gaggtggatg tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag
    38041 agtatgagtt acgattcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga
    38101 aatttctcca aaggccagta taccatgatg cactcgctga tttatcggac agatttgttg
    38161 cgtgctagcc agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt
    38221 acgccccttc agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg
    38281 attgggcgtg aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa
    38341 ctcaaggtca atcgactctt gatagaccaa cttgatttgt cccaagtgag tcatcccaaa
    38401 atgcgagaat atctgctgaa tcatattgaa ctcacgacgg tgatttccag taccctgctc
    38461 aaccgatctg gaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag
    38521 cagaaaaatc cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa
    38581 cattctgtct tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt
    38641 tatggattta attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt
    38701 cttagtcctt tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa
    38761 ggagaatcct atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct
    38821 cagtgtcggt gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc
    38881 aagttctgta cgtgccgatg ggctcaatcc aaccccaggt caagtcttac ctgaagagac
    38941 accgggaacg aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc
    39001 gaaacctgag ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga
    39061 agtgagcgag gaaacaagcc cttctagtct ggatacactt tttgaaaaag atgaagaagc
    39121 tcaaaaaaat ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga
    39181 tgggacacaa gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga
    39241 aaatacaaaa gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg
    39301 tcctttcact gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat
    39361 gttaactcgt ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc
    39421 taaaaatcct gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt
    39481 agacttaaat ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc
    39541 taatggtact caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc
    39601 tgacttgact aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc
    39661 taaagaaaca gttcaaaaag ccgttgcaga caacgttaaa gacagtatcg atgttccagc
    39721 agcctaccta gaaaaagcca agggtgaagg tccattcaca gcaggtgtca accatgtgat
    39781 tccatacgaa ctcttcgcag gtgatggcat gttgactcgt ctcttgctca aggcatctga
    39841 caaggcacca tggtcagata acggcgacgc taaaaaccca gccctatctc cactaggcga
    39901 aaacgtgaag accaaaggtc aatacttcta tcaagtagcc ttggacggaa atgtagctgg
    39961 caaagaaaaa caagcgctca ttgaccagtt ccgagcaa
//
LOCUS       DAVIME010000017        36278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVIME010000017 DAVIME010000000
VERSION     DAVIME010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.017"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            225..1706
                     /locus_tag="VV588_000909"
     CDS             225..1706
                     /locus_tag="VV588_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU7083276.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2068..3069
                     /locus_tag="VV588_000910"
     CDS             2068..3069
                     /locus_tag="VV588_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU7083277.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3220..4137
                     /locus_tag="VV588_000911"
     CDS             3220..4137
                     /locus_tag="VV588_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7083278.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4148..5038
                     /locus_tag="VV588_000912"
     CDS             4148..5038
                     /locus_tag="VV588_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU7083279.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5067..6683
                     /locus_tag="VV588_000913"
     CDS             5067..6683
                     /locus_tag="VV588_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU7083280.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6693..8012
                     /locus_tag="VV588_000914"
     CDS             6693..8012
                     /locus_tag="VV588_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU7083281.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8222..8294)
                     /locus_tag="VV588_000915"
     tRNA            complement(8222..8294)
                     /locus_tag="VV588_000915"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8259..8261),aa:Lys,seq:ctt)
     gene            complement(8559..9830)
                     /locus_tag="VV588_000916"
     CDS             complement(8559..9830)
                     /locus_tag="VV588_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU7083282.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10100..10300
                     /locus_tag="VV588_000917"
     CDS             10100..10300
                     /locus_tag="VV588_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083283.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10504..10683
                     /locus_tag="VV588_000918"
     CDS             10504..10683
                     /locus_tag="VV588_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083284.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10820..10999
                     /locus_tag="VV588_000919"
     CDS             10820..10999
                     /locus_tag="VV588_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU7083285.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            11036..11488
                     /locus_tag="VV588_000920"
     CDS             11036..11488
                     /locus_tag="VV588_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU7083286.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11779..12249
                     /locus_tag="VV588_000921"
     CDS             11779..12249
                     /locus_tag="VV588_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU7083287.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12305..12847
                     /locus_tag="VV588_000922"
     CDS             12305..12847
                     /locus_tag="VV588_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083288.1"
                     /translation="MLEKVKQFFRSRSAKTEPSVDILPRNRFEDLDFERVLKSGARRL
                     VNEEGRYAEDGKITELEFPEDFAEFEFLVGFKTEEEEQFQQLLARLNSIDNAIQSYLE
                     SEMQQPIPQYAKDLGYTQKRWEKTFYFHPWILSGEENPPNLRYVADYVNDEFTVYFAK
                     KHGRWQAYWDAECQKVIEES"
     gene            12897..13061
                     /locus_tag="VV588_000923"
     CDS             12897..13061
                     /locus_tag="VV588_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEU7083289.1"
                     /translation="MELLNSRMDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPG
                     GGKSVRENLI"
     gene            13171..14205
                     /locus_tag="VV588_000924"
     CDS             13171..14205
                     /locus_tag="VV588_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU7083290.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14207..16450
                     /locus_tag="VV588_000925"
     CDS             14207..16450
                     /locus_tag="VV588_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008288790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEU7083291.1"
                     /translation="MNTLLTLRGKSFTPKSAKGRGPITIPADSIVTLNHLNELYTSLE
                     RVKEYWSNNTIIDGVLISVYYNRVLAKSNRIDGFFNVGGGNAIPNETIVGAKFSNDKS
                     RHIITHYISKEVLDKTIEHTKKVITIFKDYFASAPMTSMVFSDSSKFNQIDYSKYGLS
                     KSKFKQYLRDACFVKGFGIEQADMSTIRNSIVTIYDVKTNLLTLLKQLDIDVSEANIM
                     DQTTVLLDEKNIELLLLKAPYLVSMIVEDFSSLSPENFYNDGNTFYNNLPFPTNEPII
                     GVIDTLFDDRVYFNEWVEYHDLISPDISKGSQDYKHGTAVSSVIVDGASLNPKLDDGC
                     GRFRVRHFGISLQSGFNSFTIIKQIREIVSQNPDIKVWNLSLGSNDEIRENFISVEGS
                     LLDEIQFDNDVIFIIAGTNGIAPDGQRKKIGAPADSLNSIIVNSVDFSNQVVSYSREG
                     VVLSFFIKPDVSYYGGGNGDFINVCEPLGLARVAGTSFAAPFIARKMAYLIHIMGLSR
                     EEAKALLIDSAIPWNDKKTFADISLLGYGVVPIKIEDILSTPDDEIKFIVSDVSRAYE
                     TYNYDFPVPISKEHYPYVAKATMCYFPKCSRNQGVDYTNTEMQLSLGVLDKKGIKTIN
                     NDNQYSENAPGYVREKSARNIFRKWDNVKHLGEKFSSRKKAKPILNPSNPQWGMSVKT
                     IERLRNDDGYGIRFGVVVTLKELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSL
                     NEEIEFE"
     gene            16501..17520
                     /locus_tag="VV588_000926"
     CDS             16501..17520
                     /locus_tag="VV588_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU7083292.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYKDFYEFQNRTYISRKENEEEYSN
                     LIYESLFSDTVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEIVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDNMRTSLPVINQPAIDKKYNENLYQHDIVNILTLNYT
                     NVIDKLYNESAKSFSNQLRTNNYKFHIAPPIHAHGTVDICTVLGVSDETQISNSFDEE
                     QKESLIKNLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDGYIWNQIAEQSIRSS
                     VPVIIYHYVPHFDAGNPTRVKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIF
                     NLMER"
     gene            17533..18483
                     /locus_tag="VV588_000927"
     CDS             17533..18483
                     /locus_tag="VV588_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU7083293.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     IFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVVAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18485..19228
                     /locus_tag="VV588_000928"
     CDS             18485..19228
                     /locus_tag="VV588_000928"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU7083294.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19239..21035
                     /gene="pepF"
                     /locus_tag="VV588_000929"
     CDS             19239..21035
                     /gene="pepF"
                     /locus_tag="VV588_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU7083295.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(21095..21367)
                     /locus_tag="VV588_000930"
                     /pseudo
     CDS             complement(21095..21367)
                     /locus_tag="VV588_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            21355..21537
                     /locus_tag="VV588_000931"
                     /pseudo
     CDS             21355..21537
                     /locus_tag="VV588_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
     gene            complement(21661..21750)
                     /locus_tag="VV588_000932"
                     /pseudo
     CDS             complement(21661..21750)
                     /locus_tag="VV588_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21747..22280)
                     /gene="queF"
                     /locus_tag="VV588_000933"
     CDS             complement(21747..22280)
                     /gene="queF"
                     /locus_tag="VV588_000933"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU7083296.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQINREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISINPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(22585..22899)
                     /gene="trxA"
                     /locus_tag="VV588_000934"
     CDS             complement(22585..22899)
                     /gene="trxA"
                     /locus_tag="VV588_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU7083297.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(22916..23137)
                     /locus_tag="VV588_000935"
     CDS             complement(22916..23137)
                     /locus_tag="VV588_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU7083298.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(23236..23616)
                     /locus_tag="VV588_000936"
     CDS             complement(23236..23616)
                     /locus_tag="VV588_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU7083299.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(23759..24712)
                     /locus_tag="VV588_000937"
     CDS             complement(23759..24712)
                     /locus_tag="VV588_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU7083300.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(24780..25991)
                     /gene="sstT"
                     /locus_tag="VV588_000938"
                     /pseudo
     CDS             complement(24780..25991)
                     /gene="sstT"
                     /locus_tag="VV588_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012962425.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            26130..26690
                     /locus_tag="VV588_000939"
     CDS             26130..26690
                     /locus_tag="VV588_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEU7083301.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQVLHFVPNRNITVVSNFSRTD"
     gene            26747..27655
                     /locus_tag="VV588_000940"
     CDS             26747..27655
                     /locus_tag="VV588_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU7083302.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            27607..28197
                     /locus_tag="VV588_000941"
     CDS             27607..28197
                     /locus_tag="VV588_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU7083303.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            28200..29306
                     /gene="yqeH"
                     /locus_tag="VV588_000942"
     CDS             28200..29306
                     /gene="yqeH"
                     /locus_tag="VV588_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU7083304.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPSLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            29520..29831
                     /gene="yhbY"
                     /locus_tag="VV588_000943"
     CDS             29520..29831
                     /gene="yhbY"
                     /locus_tag="VV588_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU7083305.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            29883..30512
                     /locus_tag="VV588_000944"
     CDS             29883..30512
                     /locus_tag="VV588_000944"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU7083306.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVAYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            30512..31105
                     /gene="yqeK"
                     /locus_tag="VV588_000945"
     CDS             30512..31105
                     /gene="yqeK"
                     /locus_tag="VV588_000945"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU7083307.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            31106..31606
                     /locus_tag="VV588_000946"
     CDS             31106..31606
                     /locus_tag="VV588_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU7083308.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            31619..31972
                     /gene="rsfS"
                     /locus_tag="VV588_000947"
     CDS             31619..31972
                     /gene="rsfS"
                     /locus_tag="VV588_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU7083309.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            32075..32821
                     /locus_tag="VV588_000948"
     CDS             32075..32821
                     /locus_tag="VV588_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU7083310.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            32831..33928
                     /locus_tag="VV588_000949"
     CDS             32831..33928
                     /locus_tag="VV588_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU7083311.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            34166..34396
                     /locus_tag="VV588_000950"
     CDS             34166..34396
                     /locus_tag="VV588_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU7083312.1"
                     /translation="MEGVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            34665..36278
                     /locus_tag="VV588_000951"
     CDS             34665..36278
                     /locus_tag="VV588_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU7083313.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
BASE COUNT        11377 a         6433 c         7902 g        10566 t
ORIGIN      
        1 ataattttta aaattaaaaa tataatcttt agacttgaat ttgattctgt attcacgccc
       61 tcaatagacg gtaaaataag aaaattgttt atatattgtc tccgtagtgt tattatacga
      121 aataaaagat tttaggaaaa gtcgttatat catgctatac ctattctttg tggtataatt
      181 gcaagaggtt taatccgata atttataaag agagaaagat attcatgaga gatttattat
      241 ctaaaaaaag tcataggcaa ttagaattat tagaattatt atttgaacat aaacgttggt
      301 ttcatcgttc tgaactagca gagttattaa attgtacaga acgtgcagtc aaagatgatc
      361 tatcccatgt taaatctgct tttcctgact tgatttttca ttcttctact aatggtatac
      421 gcattattaa taccgatgat agtgatattg aaatggttta ccatcatttc tttaaacatt
      481 caactcattt ttcgatttta gaattcatct tctttaatga aggttgtcaa gctgagagta
      541 tttgtaaaga attttatatc agttcatctt cgctctatcg tattattagc caaatcaata
      601 aagtgattaa aaggcaattt caatttgaag tcagtctgac ccctgttcaa atcattggaa
      661 atgagagaga cattcgttac ttttttgcac aatatttttc agaaaaatat tatttcctag
      721 aatggccatt tgaaaatttt tcatcagagc cactatctca attgttagaa ttggtttata
      781 aggaaacaag ctttccaatg aatttgtcaa cgcatagaat gctaaagttg ctcctagtta
      841 cgaacctata tagaataaag tttggtcatt ttatggaagt agataaagat tcttttaacg
      901 accaaagttt ggatttttta atgcaggcag aaggaataga aggtgttgct cagagttttg
      961 aatcagaata caatatctct ttagatgaag aagttgtttg ccaattattt gtgtcttact
     1021 ttcaaaaaat gtttttcata gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt
     1081 atgttgaaaa atcttaccat ctattgagtg attttattga tcagatttca gtcaagtatc
     1141 agattgaaat ggagaataag gataatctga tttggcatct gcataatacc gcacatctgt
     1201 atcgtcaaga gttgtttact gagtttattt tatttgatca aaaagggaat acaatcagga
     1261 actttcaaaa tatttttcca aaatttgttt cagatataaa aaaagagctt tctcactatt
     1321 tagagactct tgaggtttgt tctagttcaa tgatggtaaa tcatctatct tataccttca
     1381 tcactcatac caaacatttg gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt
     1441 tagttatgag taattttgat cagtatcatg caaaattcgt tgcagagaca ctttcttatt
     1501 actgtagcaa taattttgaa ctggaagttt ggactgaatt agaattatca aaggaatctt
     1561 tagaagattc accttatgat atcattattt ctaattttat tattcctcct attgaaaata
     1621 agagactcat ctattcaaat aatataaaca cggtctcact catatacttg ttaaatgcca
     1681 tgatgtttat tcgattagat gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg
     1741 aactgtacct caaaagttag acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa
     1801 agaccttcaa tcatttaagc aaaatgtaca tctagattta tagccctcta aaactcttgc
     1861 tttttttgta gaagatacga aaaaagccat aaaaccaagg cttttcctgt tttatgtaga
     1921 tgtttacaca tgaaaattga agtattttca aaagctaatt ggagtgattt tattcatgat
     1981 gggataaatg atctggccaa aaatgattga gaaatagttg cttaaaaagc atttgcatga
     2041 tactatatat tgaaaggagg tgataatatg gtagaacaaa gaaaatcaat taccatgaaa
     2101 gatgttgctt tagaagcagg agttagtgtt ggaactgttt cacgtgtaat taataaagaa
     2161 aaaggcatta aagaagtaac tttgaaaaaa gtggaacaag cgattaaaac tttgaattac
     2221 attccagatt actatgctag aggaatgaaa aaaaatcgaa cagaaacgat tgcaatcatt
     2281 gtaccaagta tctggcatcc cttcttttca gaatttgcta tgcatgtgga aaatgaagtc
     2341 tataagagaa ataacaaatt actcttatgt tctataaatg gtacaaatag agagcaagac
     2401 tatctggaga tgttgcgtca taataaagtt gatggagtgg ttgccattac ctatagtcca
     2461 attgaacatt acttgacgtc aggaattccc tttgttagta ttgaccgcac atactcagat
     2521 attgccattc cttgtgtttc atcagataat gatgcaggtg gaagagaagc agctaaacaa
     2581 ttaattagta aaggatgtca gcatttagcc tttgtgggcg gacataatac aaccattaat
     2641 gaaaccaaac gtcgtagaat ttcatttgaa aagtatgtcc aagagcataa aatacctctt
     2701 agtatttttg atttggatga gacagttact gactattatg gaaagctaga gagtttcttg
     2761 gaagaaaatt cttctataga tggaattttt acaatcaacg attttacagc tttggatgtg
     2821 attgaaatac tagaaaaaaa tggcaaacgt attcctcatg atgtccaaat tattggatac
     2881 gatggaatta aaatggctgg agatagagat tatctacttt caactattga acaaccattg
     2941 gaagaaatgg caaaagaagc ggttcgtatt ttgtttgata taattgatgg aaagactgtt
     3001 aatttgcaga caatcctacc agtaaaattt gttgaaggaa aaacaacaaa aaatgaaaat
     3061 aagtcttgac agaaagcgct atcaatgata gaatgaattc agataaaaag atttattttt
     3121 aaaacaaaaa tgaaacgttt caaaaaaaga aataaaaaga cagcgccaag cgctatcttt
     3181 tatagaaaaa atgaaacgtt tcaaaaaaag gaggttgcta tgaatagcaa agcgaagcaa
     3241 gtttctcttt gggaaagaat caagaaacaa aaactcttgt tattgatgac tgtccccggt
     3301 ttagttttaa cctttatctt taaatacatc cctatgtatg gggttttaat cgcatttaaa
     3361 gattacaatc ctttaaaagg aattttaggg agtgattgga ttggtttttc tgagtttaca
     3421 aaattcatat cctctcccaa ctttggtatc ttgttagcca acacattaaa attaagtatc
     3481 tatggtttat tgcttggctt tttaccacca atcattcttg cgattatgct caatcaactc
     3541 ttgagtgaaa aagtcaaaaa acgaattcag ctcattttat acgcaccaaa ctttatctca
     3601 gtcgttgtta ttgtcggtat gattttcctc ttcttttcag tgggaggacc aatcaacaat
     3661 tttctttcta tgtttggaat gaaggctgac ttcttgacaa atccagactt ctttagaccc
     3721 ttatacatct ttagtggtat ctggcaagga atgggctggg cttcaacgct ctacacggca
     3781 acattggtaa atgtagatcc agccttagta gaagcagctc gactggatgg agccaatatc
     3841 ttccaacgaa tctggcacat tgatattcca gctcttaagc ctattatggt tatccaattt
     3901 gttttagctg caggtggaat tatgaatgtc ggatatgaaa aagcattctt gatgcagaca
     3961 tcgttaaatt tgccaacttc tgaaattatc tcgacatatg tctataaagt tggtcttgta
     4021 tcaggagact attcttactc aacagcggtt ggtttgttta atgcagtgat taacgtagta
     4081 ttgcttgttg cagttaacca aatcgttaaa cgcatgaata atggtgaagg aatttaagga
     4141 ggaaagtatg aaaaattcga ttatggatac aaaatttgat agacgtatct tactcttaaa
     4201 taaaatcatt attgtcttta tcgttttgat gactttgctt cctttacttt atatcgtcgt
     4261 agcatccttt atggatccta aggttctggt tagtagaggg attagcttta atccagccga
     4321 ttggactgta gaaggttacc agcgtgtatt cagtgaccaa tctattctaa gaggttttat
     4381 caattctcta ctatactctt ttggatttgc agctttaaca gtattgctat ctgtgtttac
     4441 agcttatcct ctttctaaga aagacttggt tggacgtcgt tggattaact acttcttgat
     4501 tgtgactatg ttctttggtg gtggtttagt cccaacttac ttgctcgtaa aagaattggg
     4561 aatgctcaat actccatggg ctatcattgt tccaggtgct gtcaatgttt ggaatattat
     4621 tcttgctagg gcctatttcc aaggattgcc tgaagaatta gttgaagctg ctgtcattga
     4681 tggagcgaat gacttgcaga ttttctttaa aatcatgctt cctcttgcaa aaccaattat
     4741 gtttgttctc ttcctctatg cttttgtagg acagtggaac tcatactttg atgcaatgat
     4801 ttatatcaag gatccaaact tggaaccatt gcaacttgta cttcgtaaaa ttctcattca
     4861 gagccaacca ggtcaagaca tgattggagc acaagcggct atgaatgaaa tgaaacgttt
     4921 agctgaattg attaaatacg caactattgt catttccagc ttgccattga ttgttatgta
     4981 tccattcttc caaaaatact ttgataaagg aattatggct ggttcactta aaggataaaa
     5041 aaagaaaaaa taaaaggagt tttctcatga aattcaaaac attctcaaaa tcagcagttt
     5101 tgttgacagc tagtttagca gtacttgcag cctgtggctc aaaaaataca gcttcaagtc
     5161 cagattataa gttggaaggt gtaacattcc cgcttcaaga aaagaaaaca ttgaagttta
     5221 tgacagccag ttcaccgtta tctcctaaag acccaaatga aaagttaatt ttgcaacgtt
     5281 tggagaagga aactggcgtt catattgact ggaccaacta ccaatccgac tttgcagaaa
     5341 aacgtaactt ggatatttct agtggtgatt taccagatgc tatccacaac gacggagctt
     5401 cagatgtgga cttgatgaac tgggctaaaa aaggtgttat tattccagtt gaaaatttga
     5461 ttgataaata catgccaaat cttaagaaaa ttttggatga gaaaccagag tacaaggcct
     5521 tgatgacagc acctgatggg cacatttact cattcccatg gattgaagag cttggagatg
     5581 gtaaagagtc tattcacagc gtcaacgata tggcttggat taacaaagat tggcttaaga
     5641 aacttggtct tgaaatgcca aaaactactg atgatttgat taaagtccta gaagctttca
     5701 aaaacgggga tccaaatgga aatggagagg ctgatgaaat tccattttca tttattagtg
     5761 gtaacggaaa cgaagatttt aaattcctat ttgctgcatt tggtataggg gataacgatg
     5821 atcatttagt agtaggaaat gatggcaaag ttgatttcac agcagataac gataactata
     5881 aagaaggtgt caaatttatc cgtcaattgc aagaaaaagg cttgattgat aaagaagctt
     5941 tcgaacatga ttggaatagt tacattgcta aaggtcatga tcagaaattt ggtgtttact
     6001 ttacatggga taagaataat gttactggaa gtaacgaaag ttatgatgtt ttaccagtac
     6061 ttgctggacc aagtggtcaa aaacacgtag ctcgtacaaa cggtatggga tttgcacgtg
     6121 acaagatggt tattaccagt gtaaacaaaa acctagaatt gacagctaaa tggattgatg
     6181 cacaatacgc tccactccaa tctgtgcaaa ataactgggg aacttacgga gatgacaaac
     6241 aacaaaacat ttttgaattg gatcaagcgt caaatagtct aaaacactta ccactaaacg
     6301 gaactgcacc agcagaactt cgtcaaaaga ctgaagtagg aggaccacta gctattctag
     6361 attcatacta tggtaaagta acaaccatgc ctgatgatgc caaatggcgt ttggatctta
     6421 tcaaagaata ttatgttcct tacatgagca atgacaataa ctatccaaga gtctttatga
     6481 cacaggaaga tttggacaag attgcccata tcgaagcaga tatgaatgac tatatctacc
     6541 gtaaacgtgc tgaatggatt gtaaatggca atattgatac tgagtgggat gattacaaga
     6601 aagaacttga aaaatacgga ctttctgatt acctcgctat taaacaaaaa tactacgatc
     6661 aataccaagc aaacaaaaac tagaggttga ttatgggaga taagaaatac acagtagaaa
     6721 aagccaatcg ttttatagca gaaaataaac atctcgttaa tactcaatat aagcctgaag
     6781 aacatttttc agctgagatt ggttggatca atgatccaaa tggatttgtc tattttcgtg
     6841 gagaatacca tctcttttat caattctatc catatgatag tgtttggggg cctatgcact
     6901 ggggacatgc taaaagtaag gacttggtga cttgggagca cttgccagtg gcacttgctc
     6961 ctgaccaaga ttatgaccga aatggttgtt tctcaggctc tgccattgtc aaggatgatc
     7021 gcctctggct catgtacact ggacatatcg aagaagaaac cggtgtccgc caagtgcaaa
     7081 atatggcatt ttcagatgac gggattcact ttgaaaagat tgaacaaaat ccagttgcaa
     7141 ctggatcaga cttgccagat gagttgattg ctgctgattt tcgtgatcca aaactctttg
     7201 aaaaagatgg acgctattac tccgtagtag ctgccaaaca caagaataat gtgggctgta
     7261 tcgttctact agggtccgat aacctagtag aatggcagtt cgaatccatc tttttaaaag
     7321 gggtagaaca ccaaggcttt atgtgggaat gcccagatta cttcgagtta gatgggaaag
     7381 attgccttat tatgtcaccc atgcgttatc agcgtgaggg agactcatat cataacatca
     7441 actcatcgct tttgttcacg ggtaaggtag attggggaga aaaatgtttt atcccagaat
     7501 cagttcaaga aattgatcat ggccaagact tctatgcgcc tcaaacattg ttggacgatc
     7561 aaaatcgtcg tatcctgatt gcttggatgc agacatgggg gcgtaccctt ccaacccatg
     7621 accaagaaca caaatgggca tgtgccatga ctttacctag aattttaaga ttggaagatg
     7681 gcaaactaag acaattccct gttaaaaaag gccaatatca aatccaaata gataaagatt
     7741 gtcattacca cttaggaaat gatatagatt atcttgaatt tggttatgat agtaatgcgc
     7801 agcaagttta cattgatcgt agccatctta ttcaaaaaat tctaggtgaa gaagaacagg
     7861 acactagtcg acggtatgta gatattgaag ctaaagaatt ggaagttgtt ctagataaaa
     7921 attccatcga gatttttgtc aatcaaggtg aagcaagctt gactgcaact tattacttaa
     7981 cggtgccagc tgagctatca cgaattgatt aaaaattaag ttatttctcc taaagaaaaa
     8041 gttctctttc taaaatagtg gaaagaggac tttttgtgtt ttgggtatat aagcttagtt
     8101 tatggtattt gtaaaattgg tgttggatta tgatttaagc tagttttcta aagaatttga
     8161 aaaaaatttt atttaagcaa aaaaaaccct tggttccaag gcttttcctg ttgtatttat
     8221 atgcccccta cagggatcga acctgtgacc cacggattaa gagtccgctg ctctgccagc
     8281 tgagctaagg aggcaaagaa aaaagctgta ttggtgccga aacttcacgg tttgtattga
     8341 acccgcgcaa ttaagcaggt gggcaactcg ctctaactga agctgtttcc gtgtgagacg
     8401 gcctacatgc tgttagaaga cttttgtttc cctaataata caaaaaatag tcggtcaaca
     8461 cttaagtgtg aagtcgtaca ccacagcgtt tctatactta tatgatacca ctttttcaaa
     8521 aaaaatcaag aggaaagtgc aattttttga aaaggatttc agatttttcg caaacggtcg
     8581 atagcttcct ttctttgagc caaagcccgt tcatatttac cagtatcttc tgcttggaaa
     8641 tagtgatgat tacgaatttt ttctggcaga tagtcttgct tgacccaatt tccaggatag
     8701 ttgtgtggat agagatagtc ttgggcattc cccagttcct tgcttccact gtagtgccca
     8761 tcacgtaggt gtcgcggaat aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta
     8821 tccatagcta cataggctga gttggatttt ggagaaaggg ccaaatcaat cacgacattg
     8881 gcaatgagaa tgcgggcttc tgggaaccca atcttctggg cagcatccag agcagtcacg
     8941 gtatgaatct gggcctcagg attggctaag ccgatatctt cataggcgat aacagtcaag
     9001 cgacgagcga gactaggcag atccccagcc tcaatcaagc gggcagtata gtggagactg
     9061 gcatccacat ctgagccacg aatagacttt tgcagggcag atagaacatc atagtgaccg
     9121 tctccatcct tgtccatagt gatgtagctt ctctgaagac tattttccat gatgtctaag
     9181 gtgatgtggc gaatgccctc gtcattctca ggggtagaga gaacagctaa gtccagtgag
     9241 ttaaaggcag agcgaaggtc tccgtttgta gaggttgcga tgaaatccag cgcatcctca
     9301 tctagttcta ttggaaaatc aaaaccacgt tcagggttac ttagagctat ctgcagggcc
     9361 tctttgacgt cttggttaga cagaggttcc aactcgaaaa tttgaactcg gctacgaatg
     9421 gcaggagtga cagagaagaa aggattttca gtcgttgctc caatcatgat gaccagtcca
     9481 ctttccaaga gaggcaagag gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct
     9541 agcaatagga cgagaccacc agaaaattta gcttcttccg agatttcttg cagtcgcttt
     9601 ttactatcaa ctgtcgcatt gaaagttcga aaggcatact tggtcgttcc agcgatggca
     9661 gaggcaatac tggttttgcc gattccagga gggccatata gaatcatgga ggacaggcgg
     9721 ttggcttcca ccatgcggcg gatgattttt ccaggtccga ccagatgctc ctgaccgatg
     9781 acctggtcga tggttttagg gcgcatgcga agcgcgagat tgtctggcat agcagtcctt
     9841 tctagcgtgg atttgagtag aatgactcat ctactatatc ttactatgtc cattctagcc
     9901 tattagttgt gatatttcaa tggttttgta ataatcaggg agtgagatag aatctttttt
     9961 actatttaat ttaatgagga gaggtatcag catgagagat ttgattttcc ttaaagctca
    10021 aaataggata gttgagccta aagaagtgga agtgctgact tgagaaataa tattgctgaa
    10081 tgtcattgta tgaactataa tgaaaagaga ggtgataagc aatggaaatg atggaccaag
    10141 tcaggaaatt ttgattttta caaaacaaat tcgtcattgg attcttagtg atcaagttat
    10201 ttcagggaaa agaaaacttt tcttccggga agatactcca aaagagattt tagatttgta
    10261 cgaaaacatt aaatctaaac ttgattttgc ttaccaataa gtttattcta ataatgggtt
    10321 gaaaaaatat gaaaaataga ataattgatg tttttgaagt agtaaatcgc atccttgtaa
    10381 taactgttga aaatcctgat ttcgaagact tgagagttaa tcatactcaa tgaaaatcaa
    10441 agagcaaact aggaaactag ccgcaggctg tacttgagta cggtaaggcg acgttgacgt
    10501 ggtttgaatt tgattttcga agagtatcag tttgtaaaaa ttggagataa aaaatataga
    10561 gtacgcagtg ttcctatgat tcattcaact ccgcctcaat ctgtcttaga tcgagatact
    10621 tttacaattg actatacaga tgatgaattg ctcgataaag aagcagtttt tactactcat
    10681 tagaaaaata ggtctgaata aattggcttc ccttagaacc acatctaggg gcttttatgt
    10741 ataatagaat aataagtatc actcctttac aatacgtgta acacgtgtta taatggtgtt
    10801 gtcaggaggt aaaagcgcta tgcctatgac acaaaaagag atggttaaac tccttacggc
    10861 ccatggttgg ataaagacta gaggcggtaa aggctcccat attaaaatgg agaagcaagg
    10921 ggaaagactt atcacaatcc ctcatggtga gctgaataag tacactgaaa gagggataag
    10981 aaagcaagct gggttgtaaa attcagcccc tgttttttga tatggaggta gtgaaatgtt
    11041 agttacgtat ccagctttat tttattatga cgacacagac ggaacagaag cgacttattt
    11101 tgtccatttc ccagattttg aatactcagc tacacaagga gaggggattt ctgaggcttt
    11161 ggctatgggg tcggagtggc tagggataac tgttgcagat ttgatagaga gtgatggaga
    11221 gttacctcag ccatcagata tcaatagctt gtctttaatt gataatgatc cttttaaaga
    11281 tgatgaagat ttcgtgtcaa cctatgacct tgataaatct tttatttcta tggtatctgt
    11341 tgatgtatca gaatacctag gaagtcagga acccataaaa aagactttga ccataccaaa
    11401 atgggcagat aagttgggac gagaaatggg acttaacttt tctcagactt tgacagacgc
    11461 tattgcagat aagaaagttc aagcctaaga ttaagcgtgg tatcgtggta atagtcaata
    11521 aaaaagcacg tccacttgtg ctagttactc gcctattgat tttatagatt tattagccct
    11581 ttcgagggct ttttatattg atttttatga gaaatgaaga aatcagactt ttaagaaaat
    11641 cactgatacc aagggtttaa atgaggtaat atggtataat taggacataa aataattttg
    11701 tggtaagatg gtagtatcta ttttagcata tttccgagca atcggggcga ttaaagagtc
    11761 gcatagaaag aggacaaaat ggcaacatac ggatttttag atgttttaga ggaagagttg
    11821 gacaagaact ttccctttga ctttgagatt agctgggaca aacgcaacca tgcggtagaa
    11881 gtgagttttc tattggaagc gcaaaatgct gcaggtgtgg agatggtgga tgaagacgga
    11941 gaggtttcat cagatgacat tctttttgag gaagcggtcc ttttctacaa tcctgccaag
    12001 tcaacagtca atgaggaaga ctatttgact gttattcctt acctgcctaa aaaaggattt
    12061 tcccgtgaat ttttagctta ttttgcgctt ttccttaaag atactgctga ggttgggcta
    12121 gatgtcctca tggacttttt ggaagaccca gaagcagagg aatttatcat ggaatggaac
    12181 caagaagtct ttgaagaagg aaaagttggc ttggaagagg gagaatttta tccttatcca
    12241 aggtattaga aaagattcta agtggacatt tttaaataat gaattcaagg agaaggggga
    12301 gattatgcta gaaaaagtca aacagttttt caggagcagg tcagctaaaa ctgagccgtc
    12361 agttgatatt cttccccgca atcgctttga ggatctagat ttcgagagag tattgaagtc
    12421 aggagctcgt cgccttgtta atgaggaagg acgctatgct gaggatggga aaatcacaga
    12481 acttgaattt cctgaagatt ttgcggaatt tgaatttcta gttggtttta agacggagga
    12541 agaagagcag tttcagcaac tattagctcg tttaaatagt attgacaatg ctattcagtc
    12601 ctatttggaa agtgagatgc aacaacccat ccctcagtat gccaaggatc tcggctatac
    12661 tcagaagagg tgggagaaaa ccttttactt ccatccttgg atattaagtg gtgaggaaaa
    12721 cccgcctaat cttcgctatg ttgcagatta tgtaaatgat gagtttacgg tttattttgc
    12781 taaaaaacat ggcagatggc aagcatactg ggatgcagag tgccaaaaag taatcgaaga
    12841 aagctagctc gtattttcct agagagtaat tgttatcata gaaaagagta aatatcatgg
    12901 aattattgaa tagcagaatg gatttccaag gttgcaagat tgccctcttt tgtggggata
    12961 agctactgac gattttgcgt gatgacaagg acgatatccc ttgtcccaac atgtgggagt
    13021 tgccaggtgg gggaaagagt gtcagggaaa atctgatata gttttgcatt aaaagaatat
    13081 cctttcaagg ttattctttt ttaattttgt cccaaaataa ttgactttgt cccaaaaata
    13141 tagtattatt tgtataagga ggaatgaatc atgaaaaaat cagatgttct tgatttaata
    13201 aagtatcatt atgagggcag agagacagaa tttagaaatc aatccatagc aattgctcgg
    13261 aacttcaata aacatggtga tacacaaata gcacaatata ttatggggtt aatgtctcaa
    13321 agtgatagat tcatgccaca aatagaaaat cctagtgagt atttgactcc tgctaaacta
    13381 gatattggtc ctctcccatt gcctctttca attatgaatg atttaaaagg aataataaac
    13441 gctgtcaatc atcatattgg aataaataaa tttttatttg tgggatctcc aggtactgga
    13501 aaaactgaaa gtgtaaagca ggtggctaga cttattggca aggaattact tgtagtagat
    13561 ttcagtcact tagtagatag taagctaggg caaacagtca aaaacttagc aactcttttt
    13621 aatgaaatca ataatcttcc tttcaagcaa aattatatca tcctatttga tgaaattgat
    13681 tccatagtgt tggatagggt taatcagaat gatttaagag aaatgggacg agtgacttct
    13741 gcctttttaa aggagttgga taggctgtca ccagaaattg tattaattgc aacaacaaat
    13801 ctttttgaaa atcttgataa agcagttacg agaagattcg atgccataat tgactttgac
    13861 cgttatactg atgaagataa agtagaagta gctactatta ttttaaatga gttattaaag
    13921 caatttaaga atgtagctag agatttaaaa ttatttaaaa aaattatcaa tagtgccaat
    13981 gtaataccga atcctggtga tttgagaaac tcaataagaa cgtcattggc atttagtgac
    14041 ccatcagatc cgcatgatta ccaaaaacgc ctgctaagaa gtttgcataa tggtagaaat
    14101 ttatctattt ctaaattatc gaagctaggt tttactgtta gagaaattga gattttgaca
    14161 ggtatttcta agagtagtgt atcacgagag ttaagcgagg attaaaatga atacattatt
    14221 gacattacga ggtaaaagtt ttacaccaaa gtcagcaaag gggaggggac cgataacgat
    14281 tcccgcagat tctattgtta cgctaaacca tttaaatgaa ctttatacat cccttgaacg
    14341 agtaaaagaa tattggtcta ataacacaat cattgatgga gtacttatta gtgtgtatta
    14401 taatcgtgtc ctagctaaga gcaatcgtat cgatggtttt tttaatgtgg gtggcggaaa
    14461 tgcaattcca aatgaaacga ttgtgggtgc aaaatttagt aatgataaga gtaggcatat
    14521 tattacacac tacatttcaa aggaagtgtt agataagaca attgagcata ctaaaaaagt
    14581 tataacaata ttcaaagatt attttgctag tgctcccatg acgagtatgg tgttctccga
    14641 ctcttcaaaa tttaatcaaa ttgattattc taagtatggt ctgtcgaaat caaaattcaa
    14701 acaatactta agagacgctt gctttgtcaa aggatttggt attgaacagg cagatatgtc
    14761 tactatacgt aattctattg taacaatcta cgatgtaaaa actaatctct taacattact
    14821 taaacaactt gatattgatg tttcagaagc taacatcatg gaccagacaa ctgttttact
    14881 tgacgaaaaa aatattgagt tactactgct aaaagcacct tatctagtat caatgatagt
    14941 agaagatttt tctagcctgt caccagagaa tttttataat gatgggaaca ctttttataa
    15001 taatctccct tttccaacta atgaacctat tattggtgtc atcgatacgt tgtttgatga
    15061 tagagtttat ttcaatgagt gggtagagta tcatgattta atttcaccag atattagcaa
    15121 aggaagtcaa gactataagc acggtacagc agtttcctcg gtaatagtag atggagctag
    15181 tttgaatcca aaactagatg acggatgtgg aagatttaga gtcagacatt ttgggatatc
    15241 tttacagagt ggtttcaatt ccttcacaat tatcaaacag attagagaaa ttgtgtctca
    15301 aaatcctgat attaaggttt ggaacctttc gcttggatca aatgatgaaa ttagggaaaa
    15361 ctttatttct gtcgagggtt cgttgttaga cgagattcaa tttgataacg atgtaatttt
    15421 tattattgca ggcactaatg ggattgcccc tgatggacaa cgaaaaaaga ttggagcacc
    15481 agcagattca ctcaattcaa ttattgtaaa ttctgttgat tttagcaatc aagtcgtttc
    15541 ttattcacgc gaaggagttg tcctgtcttt ctttatcaaa cctgatgttt catactatgg
    15601 cggggggaac ggagacttca taaatgtttg tgaaccacta gggctggctc gagtagctgg
    15661 gaccagtttt gcggctccat ttattgctag aaaaatggct tacctcattc atattatggg
    15721 attaagtcgt gaagaagcaa aggctttatt aattgattca gcgataccat ggaatgataa
    15781 aaaaacattc gcagacattt ctttacttgg atatggggtt gtgccaatca aaatagaaga
    15841 tattttgtct acacctgatg atgaaattaa atttatagtc tcagatgttt ctagagcata
    15901 tgaaacttat aattatgatt tcccagttcc aatttctaaa gaacactatc catatgtagc
    15961 aaaggccact atgtgctatt ttccaaagtg ttctagaaat caaggagttg actatactaa
    16021 tacggaaatg caacttagtt tgggagtttt agataagaaa ggcattaaaa caattaataa
    16081 cgacaatcaa tattctgaaa atgcaccagg atatgtgaga gaaaagtcgg cacgaaatat
    16141 ttttaggaaa tgggataatg tcaaacattt aggagaaaaa ttttcttctc gtaaaaaagc
    16201 taagccgatt ctgaatcctt ctaatcctca atggggaatg agtgtaaaaa caattgaacg
    16261 gttaagaaat gatgatggtt atggtatccg ttttggagta gttgttactc taaaggagtt
    16321 gaatggtgtc aatagaatcg aagattttat tcaacaagcc gaattacgcg gttggctagt
    16381 taatagattg caagtagaag ctcaagtaga cctctttaat agtttaaatg aagaaattga
    16441 atttgaatag tggatatttt atccttattc tagatcttag gaacacaaga gggcaaagat
    16501 atgaatatta cttatatagt tggaaatggt ttggatttgc aatatggttt gaaaacaaga
    16561 tataaagatt tctatgaatt tcaaaatagg acttacataa gtaggaaaga gaacgaggaa
    16621 gaatattcaa atctcattta tgagtctcta ttttctgata cagtaaatga ttatgaaaat
    16681 tggtcagatt ttgaattgtc aattggtaaa ttaacaaaag ataacgacct catctcctca
    16741 agtatagaaa taaaggagaa atttatagat gattttagtg aaatagttga tgatttaaga
    16801 gaatatctac gcatacaaca agaaaaaaat cttgagaaag gtaatgcaat tgactttata
    16861 agcactctag ataatatgag gacctctctc cctgtaatta atcaacctgc tatcgataaa
    16921 aaatataatg aaaatctata tcaacacgat atcgtgaata tattaactct taattacaca
    16981 aatgtaatcg ataaattata taatgagtca gcaaaatcat ttagcaatca attacgaact
    17041 aataattata aatttcacat tgcgcctcca attcatgcac atggaacggt agatatttgc
    17101 acagttttag gagttagtga cgagacacag atttcaaata gttttgatga agaacaaaaa
    17161 gaatccttaa taaaaaattt agttttgaag aactatagag aaaatatgga tgttaaaaat
    17221 agcgatatta taaaaaattc tgacatcata attctttatg gggtttcttt gggagagact
    17281 gatgggtata tctggaatca gattgctgaa caatcaatca gaagttctgt tcctgtcata
    17341 atttaccatt atgtacctca ttttgatgca ggaaacccca ctagagtaaa acgcttatat
    17401 agaaatgtag aagacaaatt catacaaaat agtggaattg atttagagtt agagaagaaa
    17461 ttaagagata accttattgt tgttattgga aagactattt ttaatctgat ggaaaggtaa
    17521 gcaaaataca taatggaaac atggcaagag ttaaaagtta cagtgaagcg tgagggagag
    17581 gagttggttt ccaatctctt gattgagctg ggagcgcaag gagtcgcaat cgaagacagt
    17641 atggactatg tgggaaatgt tgaccgcttt ggcgagattt tcccagaggt ggagcagcaa
    17701 gaagaaatcg tagtgacagc ctactaccct gacacggtgg atgtgacagt ggttgaggcg
    17761 gatttgcagg ctcgtctagc agaattgaca gattttatgg atttgggaga gttaaaaata
    17821 ggtacgactg ccttggctga ggaagactgg gcagacaact ggaagaaata ctatgaacct
    17881 gctcgcatca ctcatgattt gaccatcgtt ccctcttgga cagactatga ggcgactgcg
    17941 ggagaaaaaa ttatcaagct ggatcctggc atggcttttg gtacgggaac ccacccaact
    18001 accaagatga gcatttttgc cttggaacag gttcttcgtg gtggcgaaac ggtgctagat
    18061 gtgggaactg gttcaggggt tctctctatt gccagctcgc ttctgggggc taaagaaatt
    18121 ttcgcctatg acctggatga tgtggcagtt cgtgtggctc aggaaaatat tgagctcaac
    18181 cctggaatgg aaaatatcca tgtagtggca ggcgatttgc ttaaaggcgt ggagattgaa
    18241 gcagatgtca tcgtggcaaa catcttggcg gatatcctca ttcatctgac agaggatgct
    18301 tatcgcttgg ttaaggatga aggttacctg atcatgagtg gcattatcaa ggataagtgg
    18361 gacatggtgc gcgagttggc tgaatcagct ggatttttcc tcgaaactca catggttcaa
    18421 ggggaatgga atgcctgtgt ctttaagaaa accaaggata tctctggtgt gattggaggc
    18481 tagcatgcag cagtattttg taaaaggcag tgctatctct cctgtcacta tcgagaacaa
    18541 ggaaaccagt aagcatatgt ttcaggttat gcgcttgaaa gaagaggatg aggttacctt
    18601 agtctttgat gatggcatca agcgcttggc gcgcgtgctg gatatggaaa atcgtcagtt
    18661 tgagttggtc caagaattaa atgacaatgt ggaactacca gtccaagtga ccatcgcatc
    18721 tggatttccc aagggagaca agctggagtt catcgctcaa aaagtaaccg aactgggtgc
    18781 tagccaaatc tgggcctttc ctgcagactg gtcagttgcc aagtgggatg gcaagaaatt
    18841 gggtaaaaaa gttgaaaaac tagaaaaaat tgcccttgga gcagccgagc aaagcaagcg
    18901 taatattgta ccaagtatta aacttttcga gaaaaaagca gattttctag ctcagctgga
    18961 ccagtttgac tctatcatag tagcctatga agaatcagct aaagaaggag aagccgctgc
    19021 gcttctgcaa gcagtcactg gtcttgaaac aggagccaaa ctgctcttta tctttggtcc
    19081 agaaggcggt ctctcacctg cagaaatcga aagttttgaa gctaagggag ccgttttggc
    19141 aggcctaggt cctcgtattt tgcgagcaga aacagcaccg ctttacgctt tatcagccct
    19201 tagtgtttta gtagaattag agaaataaga ggaagaaaat ggaacaaaaa caccgttcag
    19261 aatttccaga gaaggaactc tgggacttaa cagccctata ccaagaccgt gaggatttct
    19321 tgcgtgcaat cgagaaagct cgcgaagaca tcaaccagtt tagccgtgat tacaagggca
    19381 atcttcacac ttttgaggat ttcgagaagg cctttgcgga attggaacag atctacattc
    19441 agatgagcca tattggcaac tatgctttta tgcctcagac gacggactat agcaatgacg
    19501 aatttgccaa tattgcccaa gctgggatgg aatttgaaac agctgccagc gtagccttga
    19561 ccttctttga cgatgccttg gtggcagcag acgaggaagt cttggaccgt ttgggtaaat
    19621 tgccacattt aacagctgcc attcgtcagg ctaaaatcaa aaaagcccac tacttagggg
    19681 cagatgtgga gaaggccttg acaaatctcg gtgaagtttt ctatagtccg caggacattt
    19741 atactaagat gcgagctggg gattttgaaa tggctgactt tgaagcccat ggcaagacct
    19801 ataaaaacag ctttgtcacc tatgagaatt tctaccaaaa tcacgaggat gctgaggttc
    19861 gtgagaaatc cttccgttcc ttctcagagg gacttcgtaa gcaccaaaat acggctgcag
    19921 cagcctatct ggctcaggtc aagtctgaaa aactcttggc tgatatgaag ggatacgact
    19981 ctgtctttga ctatcttcta gctgaacaag aagtggaccg tgtcatgttt gaccgccaga
    20041 ttgacctcat catgaaggac tttgcaccag tcgctcagag atacctcaag catgttgcca
    20101 aggtaaatgg tcttgaaaag atgacctttg cagactggaa attggacttg gacagcgccc
    20161 tgaatcctga agtgactatt gacgatgcct atgatttggt catgaagtcg gtagaacctt
    20221 tggggcaaga atattgtcag gaagttgctc gttaccaaga agagcgctgg gtggattttg
    20281 ctgctaacag tggcaaggat tccggtggtt atgcggcgga cccatatcgc gtacaccctt
    20341 atgtactcat gagctggaca ggccgtttga gcgatgtcta taccttgatt catgaaatcg
    20401 ggcattctgg tcaattcatc ttttcagaca atcaccaaag ctatttcaac gcccacatgt
    20461 cgacctatta tgttgaagca ccgtcaacct tcaatgaatt gctactcagt gattacttag
    20521 agaaccagtc taatgaccca cgtcaaaaac gcttcgctct ggctcatcgc ttgacagaca
    20581 cctacttcca taatttcatc acccacctct tggaagccgc cttccagcgt aaggtgtata
    20641 cattgattga agaaggggag acctttggag caagcaagct caacagcatt atgaaggaag
    20701 ttttgacaga tttttggggc gatgccattg aaatcgacga cgatgcagct ttgacttgga
    20761 tgcgccaagc tcactactat atgggcttgt atagttacac ttactctgct ggtcttgtca
    20821 tctcgacagc tggttacctt catcttaaaa actcagaaac tggagctgaa gactggctca
    20881 atctcctcaa atcaggtggt agcaagacac cacttgagtc agccatgatt atcggtgctg
    20941 atatttcaac agacaaacca ctccgtgata ccatccaatt cttgtctgac acagttgacc
    21001 agattatcgc ctacagtgct gagttggggg agtaagggga tagagaagtt gttatagaat
    21061 gggtatggac agttatttgc ttaaaagtcc atgtttaaat cccccattcc ttttcgagga
    21121 attctttgcc cttctctgta atggtaagtg aacgtggcgt ttgtgcaggg atgaccaatt
    21181 gtttttcact gaaaaattct aaaagagcat tgccgagagc tccgccgaca tgatttttac
    21241 gttcgctcca atccaaacat ttagggcaaa atttccgttt tttctttttc aattcatccg
    21301 tatcaatgtg taattttctt tggaaataag acttcccagc ttcagtgagt tggaagtctt
    21361 tttctgatcg gattgaagat tactggactt tcagtaaacc cagctcgtag cttggcacca
    21421 gctgtcttgg tgggcggcgc agcccttcaa caagtttgga ttttcatcct tgcaccaatc
    21481 gctggtggag ttcttgcagc ccttgttgca aaaaatttcc ttggaacaga agaataattg
    21541 aaactcaaaa agccttgctc ctcatcttga ggaacagggc tttttcgtat gatactcttc
    21601 gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtatggttac tgacttcgtc
    21661 agttctatcc acaacctcaa aacagtgttt tgagtaacct gcggctaact tcctagtttg
    21721 ctctttgatt ttcattgagt atgactttag cggttgtcaa ttttctctgg ataaaggtcg
    21781 tgttggaaga ggcgttgttc tgccaagccc tcatacttag ttccttgctt accgtagttg
    21841 tagtaggggt tgattgaaat gccaccgcgc ggagtgaatt tcccccagac ttctaaatag
    21901 cgagggtcta gcaagttgac caagtctttc ccgatggtgt tgatacagtt ttcgtggaaa
    21961 tctccgtggt ttcggtagct aaatagatat agtttgaggg attttgactc gacacagagt
    22021 ttgtcaggaa tgtaggaaat atgaatcgtc gcaaagtctg gctgagcagt gatttgtccc
    22081 agcagagaca tatcgaggat atggtgacga atgccctgtt ccttagcgat ttctctatta
    22141 atttgaattt cgaggtgatg acgttggccg taggcaaagg tgacagcttc gactgtttca
    22201 tagtgttgca tggcccagaa aaggcaggtt gttgaatctt gaccaccact aaagacgacc
    22261 aaggctgatt gacgtttcat agtactcctt ccaaaatggg aaatgttcag agcatgcaaa
    22321 aagctcccat tagggagcta aaaaatacca aatcgagttt ttttagcgat ggcatatccc
    22381 aaacatcgta atattctact tatatagtaa aatgaaataa gaacaggaca aatcgatcag
    22441 gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa
    22501 tctgctatag tctagcatat tttttgaaaa atggcaaagg gcaagaaaaa agagaccaaa
    22561 gaaagtactt ggtctctcgt ttgattagct caattcagca atgatggcct tgatttgttc
    22621 tgctgtgtga acacctgcaa cttgtttgac aacttggccg tcttttttga agagaagagt
    22681 tggaatagac atgattccaa aagcacgagc tgtgtttgga ttttcatcaa cgtccatttt
    22741 aacgattttc aagacatctt ctgaaagttc ttcagacaat ttgtccaaga ttggaccttg
    22801 catacgacat ggaccacacc aagttgccca gaagtctact aagaccaaac cgtcttttgt
    22861 ttcttgttcg aatgttgcat ctgtaattgc ttttgccatt gtatttctcc tttttttagt
    22921 tatattggct taaatcttgt ttcatgagat agaagaagat atctccataa gtcccatggt
    22981 agtccaaatt atgacccttg taagttaatt tttggacagg gtagtagtct gcgacgccga
    23041 taaggcaagc ttgttgcgaa cgttcaaagt cttcataaga ctcgaaagtc acagttcttt
    23101 cgttcttgct ggcatctata taggtaattt caatcatgtt taaaactcct ttgtttaatg
    23161 ctaactttat tttactcctt ataaaagaga atgtcaagaa aaatgattgc gcacgcaact
    23221 ttttttaaaa tcatcttaaa tcaagaaatc caaacctgct tccaagcttt cttcgacagt
    23281 cttttgtagc gaggccagtg tcttttgccc atcatttgtc aggcagataa aactagagcg
    23341 tctatcttga tggcaacaca tgcgactgag tagaccgcaa tttttagctt ccaagcgagc
    23401 caccatccta gaaactgcgc tcgggctcag atgaagctta tctggcaggt caatctggcg
    23461 tagagatttt tcttcagcca agtccagata gtagagcagg tagaactctt tcaaggtcag
    23521 actttgctcg ctctgttggg caatggtctc ttccaagaga ctttcaattt ctttctgacg
    23581 ccgattgaag tcaaaccatt tttccaaata ggtcatagtg tctcctttct ttttagagtc
    23641 ataaatagaa gaaagtccat taacgggcag tctctgcgtc acaagatgat tgcgcatgca
    23701 ataattatac tacttttcaa gaatgctggc aagctctgtt ttttagtggt tttatttttt
    23761 actgtctata tttttggtaa aaatcaactt ttacttggat gaaggttttg gcttcacgta
    23821 ggagttgaag aagggtggcg cgggtttcaa actcttctct tgttttgggc agactgcggt
    23881 tccggaagac ttccagataa cgttcaattt catctagcaa atcagaagca ggattggtct
    23941 ggctcagttg acctgcaatt tttgaaaaga gttgcgctaa gatcaggctt tcactggcgg
    24001 caaggtgaca agtgttaatc tgttgggcca tgtttctcag gatacgactt tgtcgctgtc
    24061 tcatctcaaa gtagtggata tggtagtcgg tctggtgaaa gaggtggtca gagtgatcca
    24121 aatagaccag tctgagggct tctttcaaaa gcgtgtctaa ttctgctacc agctgtgctc
    24181 ggttgcgtcc gtctcctctg gataaatagt atttgaagcg ctggaggata tcttttaact
    24241 tttcttccac cagcgtgtgg tagtgctgga tttcctcttc tcgtgaaggc atatagagat
    24301 taacaagcaa ggcaaatcct gtaccaatag caaagagaag gaattcgttg actaggaggt
    24361 ctggagaggt tgactcttga accaagagat ggctaaccaa aaccgtgctt ggtgtgatgc
    24421 caatttccca gcccatcttg taggctaaag gaacgtagaa ggccagatag aggccgagac
    24481 tccagatatg aaatccgctc aagtgaaaag ctagaacacc gatagccaga gctagaagca
    24541 tagaaaaaag acgattgcga gccagtttta aagtacttct acgcgtatca gataggctca
    24601 agagagcgat aattccagcc gaaactgctg acgaaagatt gagaaaataa gcaagcaggc
    24661 aggcaagaca ggtagctaag atgagcttgg tcgtacgttg gctaatagac ataagaattt
    24721 cctaataagt tagaataaaa gcgtaaaaga caagacatga gcaggcttgc cttgatgagt
    24781 tattttttac gggttgctgc gtattcggca acggcggtaa agaggacatc tgtagaagaa
    24841 ttaagggctg tttcacatga gtcttggatg acaccaatca caaaaccaac cccaacaact
    24901 tgtatggcaa tatcgttaga aataccgaaa aggctacaag caactgggat aagaaggagg
    24961 gaacctccgg caatacctga agcaccacag gctgagatag ctgctaccac actgaggaca
    25021 aaggctgtgg caaagtcaac aggaattcca agagtgttaa ctgcagcaag ggtcaaaagg
    25081 ttaatggtaa tcgctactcc agccatattg atagtagaac cgagtgggat agaaacagaa
    25141 taggtatctg ggttgagtcc aaggtcatgg cagagtttca tgttgacagg aatgttagtc
    25201 gcagaactac gagtgaaaaa ggctgtcaca ccgctgacac ggaggcagtt ccaaactaga
    25261 gagtaaggat tgcgtctcat aaagaagaag gcaatcaaag ggttgaccac aggggcaaca
    25321 aaaagcatag tcgttactaa tggaaccaat aaaataccgt agttggcaag gcttccgact
    25381 cccttgtcag aaatggtttt aaaaacaaga ccaaggattc caaatggagc cagattgatg
    25441 atccattcga caattttaga agtcacgtca gcgatagttt ttagcaattc tttactattt
    25501 ttactggctt ctctcatagc gattccaaaa atgactgccc aagataagat tccaatatag
    25561 ttagcagtaa acagggcgcg ttgactgggc tgtcaaccag tttgagcaag aggttgctga
    25621 ggatctgccc aaccccatct ggtggtgcaa tttcagtatt ggcactattt agggtaattt
    25681 caatagggac gatgaaactt gctagtacag ctacaagagc agcggcgaaa gtccctatca
    25741 taggatatac aagaaaacaa cagttttcat attgctatct tgtccctttt gatgttggga
    25801 aagggcattg gcaacgaggg caaagactag gataggagca acagctttta gacctccaac
    25861 gaataaatcc ccgagtagcc caatccctga gagattagga agggtcagtc ctaggattcc
    25921 ccacaaagca taccaatcaa gatacgcttg acaaggcttg ccttattcca agcatgaatg
    25981 attcttttca taataatctc ctttttgtgt agtgattatg attatagtat aaatgataga
    26041 caaaatcaag aattttctgt ctattttttg aatatttatg gagaatgaga ctgatgaaaa
    26101 tatggtataa tgaaataaag gagttttata tgcaaaaatt tattcaggct tatattgaaa
    26161 agctagatgt gacaaccatt atcgagaata ttctaaccaa ggtcatttct cttttactgc
    26221 ttttgattgt attttatatt gctaaaaaaa tgcttcatac catggtgcag agaattgtca
    26281 aaccttctct aaaaatgtct cgtcatgatg ttggacgcca aaaaaccatc tcacgtttac
    26341 tagaaaatgt gtttaattat acgctatatt tctttttact ctactgcatt ttgtcgattt
    26401 taggtttgcc agtttctagt ttgctggctg gagctggtat tgctggggta gcgattggta
    26461 tgggagccca aggctttctg tctgatgtca tcaatggctt tttcatcctc tttgaacgtc
    26521 aactggatgt gggagatgag gtcgttctga caaatggacc gattactgta tcgggtaagg
    26581 ttgtcagtgt gggaattcgt acgacacagc ttcgtagcga ggagcaagtc cttcactttg
    26641 tccctaaccg aaatatcaca gttgttagca atttctcacg cacagactag acctgttatt
    26701 ttaagtaatt tgtggtacaa tagagggagt ttaataagga gaaaagatgg ttttagaaaa
    26761 gcagttgggc aatggttgta cctggataga cctagaccta ggaaagttga ataaactaga
    26821 agacctttct gaaatttacg gtttggacaa ggaaaccatt gaatacgcac tggatagaaa
    26881 cgagcgcgcc cacatggact accaccgtga aagtgggacg gttaccttta tctataatgt
    26941 cctagacgta aaaaaggaca aggcctacta tgagactttt cccatgacct ttattgtcga
    27001 gcatcgtcgc ctgattacca ttagtaatac caagaacgcc tatgtcattg aacagatgac
    27061 tcgttatctg gagagccatg acacgctttc gatttataag tttctctttg ccagtctgga
    27121 aattatcagc aatgcctact atcctgtcat tgagcagatg gacaagagta gggatgaggt
    27181 caatgacctc ttgcgccagc gaactaccaa gaaaaacctc tttgccctgt ctgatttgga
    27241 gactggtatg gtttatctga cggcagctgc caaacaaaat cggattttgt tagagcatat
    27301 tcaaggtcat gccttgtatc gtagttttga tgagattgag agagaacagt ttgatgatgc
    27361 catgattgag gctcatcagc tggtatccat gacagaccta atctctcaga ttttacagca
    27421 gctttcagcc tcttacaaca atattctaaa caataatctg aatgacaatt tgacaacctt
    27481 gactatcatt tcagtcttgc tagctgtttt ggcagtcgtg acaggctttt tcggaatgaa
    27541 tgttccctta cctttaacag atgagcccca tgcttggctc tatatcagtt tggctagtgc
    27601 aggtttgtgg attgttttat ccttgttact aaggaaaatt gcgaaaaaaa gttaagaaaa
    27661 ggagccagaa tggcgattga aaattatata ccagattttg ctgtggaagc agtctatgat
    27721 ctgacagtcc caagcctgca ggcgcaggga atcaaggctg ttttggtcga tttggataat
    27781 accctcattg cttggaacaa ccctgatgga acgccagaga tgaagcaatg gctacatgac
    27841 cttcgggacg cgggtattgg cattatcgta gtgtcaaata acaccaaaaa acgcgttcaa
    27901 cgagcagttg agaaatttgg gattgattac gtttattggg ccttgaagcc cttcacattt
    27961 ggtattgacc gtgctatgaa ggaattccac tatgacaaaa aggaagtggt catggttggt
    28021 gaccagctca tgacagatat acgagcagcc caccgtgcag ggattcggtc aattttagtc
    28081 aaacccttgg tccaacatga ctcaatcaaa acgcagatta accgaactcg tgagcgtcgt
    28141 gttatgagaa aaatcactga aaagtacgga ccgattacat ataaaaaagg aatttaacta
    28201 tggaagaaat tctctgtatt ggttgtggag caaccattca gacgacagat aaagctggtc
    28261 ttggttttac cccccagtcg gcacttgaaa aaggtttgga gactggcgaa gtctattgcc
    28321 aacgctgttt ccgtctccgc cactacaatg aaatcacaga tgtccagttg acgaacgatg
    28381 atttcctcaa gctcttgcac gaggtgggag acagtgatgc tttagtggtc aatgttattg
    28441 atatctttga ttttaatgga tctgtcatcc caggtttacc acgtttcgtc tcgggcaatg
    28501 atgtcctctt ggtaggaaat aaaaaagata tccttcctaa gtcagttaag tctggtaaga
    28561 ttagccagtg gctcatgaaa cgtgcccatg aagaaggtct tcgtccagtc gatgtggtcc
    28621 taacttcagc acaaaataaa catgccatta aggaagtcat tgacaagatt gaacactacc
    28681 gtaagggccg cgatgtctat gtggtcggtg tgaccaacgt tggaaaatca actctaatca
    28741 atgctattat ccaagaaatc acgggtgatc agaatgtcat cactacttca cgcttcccag
    28801 ggacaacctt ggacaaaata gagattccgc ttgacgacgg atcttatatt tacgatacgc
    28861 cgggaattat ccaccgccac cagatggctc actacttgac ggccaaaaac ctcaagtatg
    28921 tcagtcctaa aaaggaaatc aagcctaaga cctatcagct taatcctgag caaaccctat
    28981 ttttaggtgg tttgggacgc tttgacttta tagcaggaga aaagcaagga tttactgctt
    29041 tctttgataa tgaactcaaa ctccatcgta gcaagcttga aggagctagt gctttctacg
    29101 ataagcacct gggaactctt ctgacaccac caaatagcaa ggaaaaagaa gatttcccaa
    29161 gtctagtcca gcatgtcttt accattaaag ataagacaga cctagtcatc tcaggcctag
    29221 gctggattcg tgtaacaggc atagcaaaag tcgccgtctg ggcaccagaa ggcgtcgccg
    29281 tcgtcacacg aaaagcaatt atttaaaaca aaatcgctga gcgaacaaag tgagctcata
    29341 tagcgatagt tattgccgtg gtgtgattgc caatctgtag attggcaagg ggcacaattg
    29401 agaccaaggc tcaattgtga ggtcaggaaa tccatttttc aaagatgaaa tctttggaaa
    29461 attagttccg accgtccctc accacctaaa ataactatcc aaaaacaagg aagaaaatta
    29521 tgtcattaac atcaaaacaa cgtgccttcc tcaacagcca ggcacacacc ctcaaaccta
    29581 tcatccaaat cgggaaaaat ggactcaacg accaaatcaa aaccagcgtc cgtcaagctc
    29641 ttgatgcgcg tgaattaatc aaggttactc tcttacaaaa cacagatgaa aacatccacg
    29701 aagtagctga aattttggaa gaagaaatcg gtgtggatac agtccaaaaa ataggacgca
    29761 tcttgatttt gtttaaacaa tctagcaaga aagaaaatcg caagatttct aagaaagtca
    29821 aagaaatcta agaccgaaac tccaaataac tgtttttata gagaaataaa ggggactagc
    29881 ctatgacaat cgaactattg actcccttta ccaaggtaga gttggagcca gaaatcaagg
    29941 agaaaaaacg caaacaagtt gggattttag gggggaattt taaccctgtt cacaatgccc
    30001 atctcattgt tgcggatcaa gtacggcaac agttgggact ggatcaagtt cttctcatgc
    30061 ctgaatacca acctcctcac gttgataaaa aggaaaccat ccctgaacac catcgtctca
    30121 agatgcttga gttggcaatt gaggggattg acggcctagt cattgaaacc attgagttgg
    30181 agcgcaaggg tatttcctac acctacgata ccatgaagat tttgacagag aagaatccag
    30241 atacggatta ttactttatc atcggtgccg acatggttgc ctatctgcct aagtggtacc
    30301 gaattgatga actggttgac atggttcagt ttgtgggggt tcagcgtcca cgctacaagg
    30361 tagggacttc ctatccagtt atctgggtgg acgtaccgct catggatatc tcgtccagca
    30421 tggtgcggga cttccttgcc caaggtcgga aacccaactt tctcctacct cagccagtgc
    30481 tagactacat cgagaaggag gggctctact gatgtcctat caagactata tcaactgctc
    30541 ccgtgaggcc ttgttggaaa aaatggcaga gcttctacct gagaaacgtc taacccattg
    30601 tctaggtgtg gagcgtgccg ctatggaatt agctcagcgc tttggtgtag atgttgagaa
    30661 agcaagtcta gcaggtcttc ttcatgacta tgctaaaaag ttgtcagatc aggaatttct
    30721 agccttgatt gaccgttacc agctagaccc tgacctcaaa aactggggca ataatgtctg
    30781 gcatggtatg gtcggaattt acaaaattca ggaagatttg gatttgcatg attcagaaat
    30841 cctgcgagcc attgaagtcc atacagtcgg tgctggtcaa atgacagacc tagataaggt
    30901 catctacgtc gcagactata tcgagcacaa tcgagccttt cctggagtag atgtggcgcg
    30961 tgagattgca agtctatcgc tcaataaggc ggtggcctac gaaacagctc gtaccgtgga
    31021 gtatctagct catcagggat tccccatata tccccaaacc cttgaaacct ataacgcctt
    31081 tgtgcactat ttgaaagaga actaaatgaa gacggctttt ataatcattg atgttcagaa
    31141 tgttttagta gaaactgggt tccagacaaa aagtctattg ggaaaaattt cttatttaca
    31201 aaaccaggct agaagcaaga atattgaaat tatctatgtt caacatattg agaactctga
    31261 agctcaaaca tcagaagatt ggcagttatc tgcgctttta aatcgaaaac ctgctgaaaa
    31321 ggtctttcag aagaagtata acagtatttt caaagaaact ggcttaaaag aatacttgga
    31381 taagcagggg attgaaaaat tagttttatg tggtatgcag acagaatatt gtgtggatac
    31441 ctctgtcaag gttgcctttg aatatggcta tcagcttatt gttccagaag gtgctgtcac
    31501 aacctttgat ggggatgaca ttccagcaga aacgattaat gaattttatg aggacatttg
    31561 ggaggagcgc tttgcagatg tcctagatta caaacatatt ttctaaaaag aggattaaat
    31621 gaacgaaaaa gaattactag aactagtcgt gaaagcggct gatgagaaac gtgcggagga
    31681 tatcctcgca cttgatgtac aagatttgac tagtgtgacg gactactttg tcatcactag
    31741 ctcaatgaat agccgtcagt tggacgctat cgcagctaat atccgtgaaa aagtagctca
    31801 agcgggcttt aaaggtagcc atgtcgaagg cgatgcagct ggaggctggg tcttactgga
    31861 cctcggtgct gttgtcgtgc atatcttttc agaagaaatg cgtgcccatt ataatctaga
    31921 gaagctatgg catgaggcga attcagtaga tatttcagaa gctcttgctt agaagatgaa
    31981 ctcagttgta gtcaactggg tttctttgct tattttagaa aaattgatag aaaggtaaag
    32041 ggctagtggt gtttaccatg gagctcttag tatcatgatt atggcgactt atgaaacctt
    32101 tgcggcggtc tatgatgcgg tcatggacga tagtttatac gacaaatgga caaatttttc
    32161 tctgcgtcat ttgcctaaga ccaaggagaa aaagaaactc ttggaactgg cttgtgggac
    32221 aggaattcaa tcagtgcgct tctctcaggc tggttttgat gtgactggac ttgacttgag
    32281 tgcggatatg ttgaagattg cggagaagag agcaacttca gccaagcaaa agattgcttt
    32341 tatagaaggt aatatgctga atttgtccaa ggcagggaaa tacgattttg tcacgtgtta
    32401 ttcggactct atctgctata tgcaggatga ggtggaagta ggggacgtct ttaaggacgt
    32461 gtacaatgcg ctgaatgaag agggagtttt catctttgac gtgcactcga cctaccagac
    32521 agatgaagta ttccctggct attcctacca tgaaaatgcg gaagattttg ccatgctttg
    32581 ggatacatat gaggacgaag ctcctcactc catcgtgcat gagctgactt tctttatcaa
    32641 ggaggctgac ggttccttta gtcgccacga tgaagtacat gaggagagga cctatgagat
    32701 cttgacctat gatatcttac tggaacaggc tggattcaag tccttcaaac tctatgcaga
    32761 ctttgaggat aaggaaccaa cagaaactag cacccgttgg ttttttgtgg cgcagaagta
    32821 ggagattagc atgaccatca caggtattat cgcggagttc aatccttttc ataatggcca
    32881 taaatacctg ctggatcagg cagagggact gaaaattgtt gccatgtcag ggaatttcat
    32941 gcagcgtgga gagcctgcta ttgtggataa gtggacaagg gcccagatgg cgctggaaaa
    33001 tggcgcagac ttggtagtgg aattgccctt tttagtcagt gttcaggcag ctgatttctt
    33061 tggtcaagga gctgtggata tcttggatcg cttgggcatt gatagtctag tttttgggac
    33121 agaggaagtt cgagattatc agaaaatcgc tgacttatac acagagaaag gtgctgagat
    33181 ggagaaattt gtggaaaatc tgcctgattc cctttcctat ccccagaaaa cccaatctat
    33241 gtggaaggaa tttgctggtc ttgatttttc aggtaatacc cccaatcatg ttcttgctct
    33301 ggcctatgca aaggcggttg caggacgaaa tatcaagctg catccgattc agcgtcaggg
    33361 ggcaggttac cattctgtga ataaagatgt ggactttgcc tcggcgacag ccctccgtca
    33421 acatcagaag gaccaagatt tcttagaacg ttttatgcct tctgttgccc tatttgagca
    33481 ggccagtaag gtgatctggg aagactattt tcccttgctc cgctatcaaa tcttgtcaaa
    33541 tcccgaccta accaccatct atcaggtcaa tcaagaaatg gctgtgcgca ttaaagaagc
    33601 tattaaaaca gcccagtctg tggaagaatt ggtcgagtta gtgactacca aacgttacac
    33661 caaggcgcgt gtcagacgcc tattgaccta tattttggtg caggctaggg aaaatgtctt
    33721 gccagaagcc attcatgtcc ttggatttac tgaaaaaggc aggcaacatc tcaagtctct
    33781 gaaaggacag gtcaatctag tcagccgaat tggcaaagaa ccttgggatg ctatgaccca
    33841 aaaagcagac cagatttacc aactaggaaa gccaagtata gcagagcaaa attttggaag
    33901 agtgccgatt agaatagaaa caaactaagt ctactaaaag gtaggctttt tgagattttt
    33961 tacgaataat actcttcgaa aatcaaattc aaatcgcgtc aacgtcgctt tgccgtactc
    34021 aagtacagcc tgaggctagt ttcctagttt gctctttgat tttcattgag tataaataga
    34081 tagaaaagaa aatcttgtac aggttcctga caatttcttt cttttcgtgt ataatagtgg
    34141 aaaagagcta aaacgaggta tggttatgga aggagttctt tactcaacat tccgaaatca
    34201 tttaaaggat tacatgaaga aggtaaatga tgaatttgag cctttgacgg tggtcaataa
    34261 aaatccagat gaggacattg tagttctttc aaagagcgaa tgggacagta ttcaggaaac
    34321 cctgagaatc gcccaaaata aggagttatc agacaaggtt ttgcgaggaa tggataaaat
    34381 tcgcgcagga cactagtcta atttacagag aatacctgag tgaaatcttg ctgttgttag
    34441 aaacaaactt cttgtattgc ataatcatta ggaagtctac tgcaaagtag gctttttctc
    34501 aagtctctac taaactacta tttctaaaca acaagtttat tttggtaaat gtgttccaaa
    34561 ttccccaaaa catattctat tttaggtttg tgaaaatcac ttttttatgg tagaatgtaa
    34621 aagaatgtat gtcattcgga ataacaataa aatgaggtaa aaacatggaa atcatgtcgc
    34681 ttgcgattgc tgtttttgcc gtcatcattg gtttagtcat tggatatgtc agcatctcag
    34741 ctaagatgaa atcatctcag gaagctgcag agttgatgct tttaaatgct gaacaagaag
    34801 caactaattt acgtggacaa gctgagcgtg aagcggattt acttgttaat gaagccaaac
    34861 gtgaaagcaa gtctcttaaa aaagaagcac tattggaggc caaagaagaa gccagaaaat
    34921 accgtgaaga agtggacgct gaattcaaat cagaacgtca agaactcaaa caaatcgaaa
    34981 gtcgtttgac agagagagct actagccttg accgtaagga cgacaatttg acgagtaaag
    35041 aacaaacact tgaacaaaaa gaacaaagta tttctgatag agcgaaaaac cttgatgcgc
    35101 gtgaagagca attagaggaa gtcgaaagac aaaaagaagc agaactagag cgtattggtg
    35161 ctctgtctca ggcagaagca cgagatatta tcttggctca gacagaggaa aacttgacca
    35221 gggagattgc cagtcgcatt cgcgaagctg agcaagaggt caaggaacgt tctgacaaaa
    35281 tggccaagga catcttggtt caagctatgc aacgtatcgc tggtgaatat gtagcggagt
    35341 caacaaactc aacagttcat ctgccagacg atactatgaa gggacgcatt attggtcgtg
    35401 aaggtcgtaa cattcgtacc tttgaaagtt tgacaggggt cgatgtgatt atcgacgata
    35461 caccagaagt ggtgaccttg tcaggatttg atccgattcg tcgtgagatt gcccgtatga
    35521 ctatggaaat gttgctcaaa gatggtcgta tacatccagc tcgtatcgaa gagttggttg
    35581 agaaaaaccg tcaagagatt gacaataaga ttcgtgaata cggtgaggct gctgcctatg
    35641 aaattggtgc gccaaacctt catccagact tgatgaagat tatgggacgt ttgcagttcc
    35701 gtacttcata tggacaaaat gttttgcgcc attcgattga ggttgctaag ttggctggta
    35761 tcatggcgag cgaacttggt gaaaatgcgg ctcttgcccg tcgtgctgga ttccttcacg
    35821 atatcgggaa agccattgac catgaggttg aaggtagcca cgttgaaatc ggtatggaat
    35881 tggcccgtaa gtacaaggaa cccccagttg tggtgaatac gattgctagt caccacggag
    35941 atgttgaagc tgagagcgtg atagcagtta tcgtcgctgc agcagatgcc ttgagcgcag
    36001 cccgtccagg tgctcgtagt gagtctcttg aaagctacat caagcgtctc catgatttgg
    36061 aagaaattgc taacggcttt gaaggagtgc aaactagctt tgcccttcaa gcaggacgtg
    36121 aaattcgtat catggtcaat ccaggaaaaa tcaaggacga caaagtcaca atcttggctc
    36181 acaaagttcg taagaaaatt gaaaacaatc tcgattatcc aggaaatatc aaggtaaccg
    36241 tgattcgcga gcttcgtgca gtagattatg ctaaataa
//
LOCUS       DAVIME010000018        34953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVIME010000018 DAVIME010000000
VERSION     DAVIME010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.018"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            973..1425
                     /locus_tag="VV588_000952"
                     /pseudo
     CDS             973..1425
                     /locus_tag="VV588_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
     gene            1444..2781
                     /locus_tag="VV588_000953"
     CDS             1444..2781
                     /locus_tag="VV588_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU7083314.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2860..3744
                     /locus_tag="VV588_000954"
     CDS             2860..3744
                     /locus_tag="VV588_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7083315.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3744..4577
                     /locus_tag="VV588_000955"
     CDS             3744..4577
                     /locus_tag="VV588_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU7083316.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLITIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4596..6689
                     /gene="nanB"
                     /locus_tag="VV588_000956"
     CDS             4596..6689
                     /gene="nanB"
                     /locus_tag="VV588_000956"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU7083317.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6702..7805
                     /locus_tag="VV588_000957"
     CDS             6702..7805
                     /locus_tag="VV588_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU7083318.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7979..8677
                     /locus_tag="VV588_000958"
     CDS             7979..8677
                     /locus_tag="VV588_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU7083319.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8696..10213
                     /locus_tag="VV588_000959"
     CDS             8696..10213
                     /locus_tag="VV588_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU7083320.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            10338..11666
                     /locus_tag="VV588_000960"
     CDS             10338..11666
                     /locus_tag="VV588_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7083321.1"
                     /translation="MKFRKLACTVLAGAVVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTNEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11918..12784
                     /locus_tag="VV588_000961"
     CDS             11918..12784
                     /locus_tag="VV588_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7083322.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12800..13639
                     /locus_tag="VV588_000962"
     CDS             12800..13639
                     /locus_tag="VV588_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU7083323.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13912..14364
                     /locus_tag="VV588_000963"
     CDS             13912..14364
                     /locus_tag="VV588_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU7083324.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCYEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14497..14805
                     /locus_tag="VV588_000964"
     CDS             14497..14805
                     /locus_tag="VV588_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083325.1"
                     /translation="MDGQGITVDEMAWIIRGIVNALIGRYIKLGAYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFAYNIAAAWDAHDKIPNNGRINF
                     "
     gene            15089..15733
                     /locus_tag="VV588_000965"
     CDS             15089..15733
                     /locus_tag="VV588_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU7083326.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15902..16819
                     /locus_tag="VV588_000966"
     CDS             15902..16819
                     /locus_tag="VV588_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU7083327.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16837..17721
                     /locus_tag="VV588_000967"
     CDS             16837..17721
                     /locus_tag="VV588_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU7083328.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGLVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17737..18588)
                     /locus_tag="VV588_000968"
     CDS             complement(17737..18588)
                     /locus_tag="VV588_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU7083329.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18788..20845
                     /gene="pbp2b"
                     /locus_tag="VV588_000969"
     CDS             18788..20845
                     /gene="pbp2b"
                     /locus_tag="VV588_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU7083330.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANDGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSELTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20856..21452
                     /gene="recR"
                     /locus_tag="VV588_000970"
     CDS             20856..21452
                     /gene="recR"
                     /locus_tag="VV588_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU7083331.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21628..22671
                     /locus_tag="VV588_000971"
     CDS             21628..22671
                     /locus_tag="VV588_000971"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU7083332.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22755..24128
                     /locus_tag="VV588_000972"
     CDS             22755..24128
                     /locus_tag="VV588_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU7083333.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            24115..24726
                     /locus_tag="VV588_000973"
     CDS             24115..24726
                     /locus_tag="VV588_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU7083334.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGQREQYLD"
     gene            24817..25521
                     /locus_tag="VV588_000974"
     CDS             24817..25521
                     /locus_tag="VV588_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU7083335.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25740..27113
                     /gene="ftsA"
                     /locus_tag="VV588_000975"
     CDS             25740..27113
                     /gene="ftsA"
                     /locus_tag="VV588_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU7083336.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            27130..28389
                     /gene="ftsZ"
                     /locus_tag="VV588_000976"
     CDS             27130..28389
                     /gene="ftsZ"
                     /locus_tag="VV588_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU7083337.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28394..29065
                     /locus_tag="VV588_000977"
     CDS             28394..29065
                     /locus_tag="VV588_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU7083338.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            29075..29614
                     /locus_tag="VV588_000978"
     CDS             29075..29614
                     /locus_tag="VV588_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU7083339.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29614..29877
                     /locus_tag="VV588_000979"
     CDS             29614..29877
                     /locus_tag="VV588_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU7083340.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29934..30659
                     /locus_tag="VV588_000980"
     CDS             29934..30659
                     /locus_tag="VV588_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU7083341.1"
                     /translation="MEWIKKVEDSYAPFLTPFINPHQEKLLKILAKTYGLACSSSGEF
                     VSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHLTHAKILGTVINQLGIERKLF
                     GDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEERPFTEKIDKLEQYRELDLSV
                     SSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDKSDYTVQVGDLISVRKFGRLR
                     LLQDKGQTKKEKKKITVQLLLSK"
     gene            30668..31456
                     /gene="divIVA"
                     /locus_tag="VV588_000981"
     CDS             30668..31456
                     /gene="divIVA"
                     /locus_tag="VV588_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU7083342.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31804..34596
                     /locus_tag="VV588_000982"
     CDS             31804..34596
                     /locus_tag="VV588_000982"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU7083343.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKIIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFADAVAEGFEEK"
BASE COUNT        10806 a         6146 c         7557 g        10444 t
ORIGIN      
        1 tttaaatttt aataaaaatt ttttaaaata aattaaaaaa cgatcctaaa agggtcgttt
       61 ttttgctaaa gttttaaaaa taaacaataa ttaagattat agtgcgttga atctatatta
      121 ggacataaca attcttaaat cattgttaga aattagtttg aatttcccaa tcaatttgtt
      181 cgatttttac atcattgcat tatatcatgt gactattaac cttgttttct cctaaaattg
      241 attttcttct tttcttatct tgtccactcg aaacaagtat tgtaagaatt tgattatttt
      301 tgaaagtact tttaatatat ttgagatagt taaaaaagat ttgaaactaa attccaaatt
      361 agaaaaagac ttgaaatgct aaaaaaaaaa agtatactct aattgaaaac ggtaacaaaa
      421 ctaatttaga gaatgaaata tagagtattt ctctcttaaa agtttttggt gaaacgagat
      481 gtagaaagga gatttagcca aagagtctat tagtgctaga ataatagatt agaattattt
      541 tagaaaaacg aagtgagcag cttataaatt caagtcccca aatagattca tactagtatc
      601 ttttgcaaaa aataaagggc gacttccttc atgaatatca atttcatcta taaggaaggt
      661 agctaattga actaacttat ttattctgtt tgtcgctaga aaaatcagac ctccttgtga
      721 agattgagga gatacttaat gaaaatcaaa gaagaaacta gcaagctagt agcagattgc
      781 ccaaaacacc gctttgaggt tgtagataag actgacgtat ataatccaag gtgaagcgac
      841 tgtggtttga agagattttc aaagagtata ggctagagag tagtgttttt atgtccttct
      901 agtagaaaat gctagacaga agaatgggga acttggatag gaaaaataga ttgagaaagg
      961 aggttagaag agatgattat tacaaaaatt agccgtttag gaacttatgt gggagtaaat
     1021 ccacattttg caacattaat agattttcta gaaaaaacag gactagaaaa tttaacagaa
     1081 ggttcgattg ttatcgatgg taatcgattg tttgggaatt gatttactta tctagcagat
     1141 ggtcaagcag gggctttctt tgaaacacac caaaaatatt tggatattca tttagttttg
     1201 gaaaacgaag aagccatggc tgttacatcg ccggaaaatg taagcgttac ccaagaatat
     1261 gatgaagaga aagatattga attatacaca gggaaagtgg aacagttggt tcatttgaga
     1321 gctggcgaat gcctcatcac ttttccagaa gatttacatc aacccaaggt tcgtataaat
     1381 gatgaacctg tgaaaaaagt tgtctttaaa gttgcgattt cttaatgtag aaagagaaga
     1441 acgatgaaaa aaatgagaaa gtttttatgt ctagctggaa ttgcgctagc ggctgttgcc
     1501 ttggtagctt gttcaggaaa aaaagaagct acaactagta ctgaaccacc aacagaatta
     1561 tctggtgaga ttacaatgtg gcactccttt actcaaggac cccgtttaga aagtattcaa
     1621 aaatcagcag atgctttcat gcaaaagcat ccaaaaacga aaatcaagat tgaaacattt
     1681 tcttggaatg acttctatac taaatggact acaggtttag caaatggaaa tgtgccagat
     1741 atcagtacag ctcttcctaa ccaagtaatg gaaatggtca actcagatgc tttggttccg
     1801 ctaaatgatt ctatcaagcg tattggacaa gataaattta acgaaactgc cttaaatgaa
     1861 gcaaaaatcg gagatgatta ctactctgtt cctctttatt cacatgcaca agtcatgtgg
     1921 gttagaacag atttgttaaa agaacataat attgaggttc ctaaaacttg ggatcaactc
     1981 tatgaagctt ctaaaaaatt gaaagaagct ggagtttatg gcttgtctgt tccgtttgga
     2041 acaaatgact taatggcaac acgtttcttg aacttctacg tacgtagtgg tggaggaagc
     2101 ctcttaacaa aagatcttaa agcagacttg acaagccaac ttgctcaaga tggtattaaa
     2161 tactgggtta aattgtataa agaaatctca cctcaagatt ctttgaactt taatgtcctt
     2221 caacaagcta ccttgttcta tcaaggaaaa acagcatttg actttaactc tggcttccat
     2281 atcggaggaa ttaatgccaa cagtcctcaa ttgattgatt cgattgatgc ttatcctatt
     2341 ccaaaaatca aagagtctga taaagaccaa ggaattgaaa cctcaaacat tccaatggtt
     2401 gtttggaaaa attcaaaaca tccagaagtt gctaaagcat tcttagaagc actttataat
     2461 gaagaagact acgttaaatt ccttgattca actccagtag gtatgttgcc aactattaag
     2521 gggattagcg attctgcagc ctataaagaa aatgaaactc gtaagaagtt taaacatgct
     2581 gaagaagtaa ttactgaagc tgttaaaaaa ggtactgcta ttggttatga aaatggacca
     2641 agtgtacaag ctggtatgtt gactaaccaa cacattattg aacaaatgtt ccaagatatc
     2701 attacaaatg gaacagatcc tatgaaagca gcaaaagaag cagaaaaaca attaaacgat
     2761 ttatttgagg ctgttcagta gatgtaaaag actagaaaat aggtgggcta gtgagctgaa
     2821 aagctctagc ccaatcttgt aaaagaaggg agaaggagaa tggttaaaga acgtaattta
     2881 actcgctgga tatttgtttt gccagctatg attatcgtag gattactctt tgtttatccg
     2941 tttttctcga gtatttttta tagctttacc aataagcatt tgattatgcc taattataaa
     3001 tttgttggtt tggctaacta taaagctgtg ctatcagatc ccaacttctt taatgcgttc
     3061 tttaattcaa ttaagtggac cgttttctca ttagttggtc aagttttagt agggtttgta
     3121 ttggctttag ctcttcacag agtacgccac ttcaagaaat tatataggac cttattgatt
     3181 gttccttggg catttcctac catcgttatt gccttttctt ggcagtggat tctaaacggg
     3241 gtttatggct acttacctaa tctaatcgta aaattaggtt taatggaaca tacacctgca
     3301 tttttgacag atagtacatg ggcattccta tgtttggtgt ttatcaacat ttggtttgga
     3361 gcaccaatga ttatggttaa tgtgctttca gctttgcaaa cagtaccaga agaacaattt
     3421 gaggctgcta agatagatgg tgcttcaagt tggcaggtgt tcaagtttat cgtctttcca
     3481 catattaaag tggttgtagg acttctagtt gttttgagaa ctgtatggat ctttaataac
     3541 tttgacatta tctacctcat tactggtggt ggaccagcca atgctacaac gacgcttcca
     3601 atttttgctt acaacctggg ttggggaact aaattgttgg gtcgtgcttc agcagttaca
     3661 gtattgctct ttatcttctt ggtggcgatt tgctttatct actttgctat catcagtaag
     3721 tgggaaaagg agggtagaaa ataatgaaga agaaatccag tatttattta gatattctct
     3781 cacatgtact tttagttggt gcgaccatcg ttgcaatttt cccattggta tggattatca
     3841 tatcttctgt caaagggaaa ggggaattaa ctcagtatcc aacacgattt tggcctgaac
     3901 agtttacatt agattatttc actcatgtta tcaacgattt gcacttcatt gataacattc
     3961 gaaacagttt aatcattgcc ttggctacaa ccctcattac gattattatt tctgctatgg
     4021 cagcctatgg tattgttcga ttctttccta aattgggagc aatcatgtcg agactactcg
     4081 tcattaccta tattttccca ccaattttgt tagcaattcc ctattcaatt gccattgcta
     4141 aagttgggtt aacaaatagt ttatttggct tgatgatggt ttatctatct tttagtgttc
     4201 catatgcagt ttggctctta gttggatttt tccaaacagt tccaattgga attgaagaag
     4261 cggctagaat tgatggtgca aataaatttg ttacgtttta taaagttgtg ctaccgattg
     4321 tagcaccagg tattgtagca acagctattt atacatttat caatgcttgg aatgaattcc
     4381 tgtatgcctt gattttgatt aacaatacag gaaagatgac agtagcagta gcccttcgtt
     4441 cacttaatgg ttcagaaata ctagactggg gagatatgat ggcagcgtct gttattgtag
     4501 ttcttccatc aattattttc ttctctatca tccaaaataa gattgcaagt ggattatcag
     4561 aaggatctgt gaagtagacg aaagaaggaa aaaaaatgaa taaaagaggt ctttattcaa
     4621 aactaggaat ttctgttgta ggcattagtc ttttaatggg agttcctact ttgattcatg
     4681 cgaatgaatt aaactatggt caactgtcca tatctcctat ttttcaagga ggttcatatc
     4741 aactgaacaa taagagtata gatatcagct ctttgttatt agataaattg tctggagaga
     4801 gtcagacagt agtaatgaaa tttaaagcag atgaaccaaa ctctcttcaa gctttgtttg
     4861 gcctatctaa tagtaaagca ggctttaaaa ataattactt ttcaattttc atgagagatt
     4921 ctggtgagat aggtgtagaa ataagagacg cccaaaaggg aataaattat ttattttcta
     4981 gaccagcttc attatgggga aagcataaag gacaggcagt tgaaaataca ctagtatttg
     5041 tatctgattc taaagataaa acatacacaa tgtatgttaa tggaatagaa gtgttctctg
     5101 aaacagttga tacatttttg ccaatttcaa atataaatgg tatagataag gcaacactag
     5161 gagctgttaa tcgtgaaggt aaggaacatt acctcgcaaa aggaagtatt gatgaaatca
     5221 gtctatttaa caaagcaatt agtgatcagg aagtttcaaa tattcccttg tcaaatccat
     5281 ttcagttaat tttccaatca ggagattcta ctcaagctaa ctattttaga ataccgacac
     5341 tatatacatt aagtagtgga agagttctat caagtattga tgcacgttat ggtgggactc
     5401 atgattctaa aagtaagatt aatattgcca cttcttatag tgatgataat gggaaaacgt
     5461 ggagtgagcc aatttttgct atgaagttta atgactatga ggagcagtta gtttactggc
     5521 cacgagataa taaattaaag aatagtcaaa ttagtggaag tgcttcattc atagattcat
     5581 ccattgttga agataaaaaa tctgggaaaa cgatattact agctgatgtt atgcctgcgg
     5641 gtattggaaa taataatgca aataaagccg actcaggttt taaagaaata aatggtcatt
     5701 attatttaaa actaaagaag aatggagata acgatttccg ttatacagtt agagaaaatg
     5761 gtgtcgttta tgatgaaaca actaataaac ctacaaatta tactataaat gataagtatg
     5821 aagttttgga gggaggaaag tctttaacag tcgaacaata ttcggttgat tttgatagtg
     5881 gctctttaag agaaaaacat aatggaaaac aggtccctat gaatgttttc tacaaagatt
     5941 cgttatttaa agtgactcct actaattata tagcaatgac aactagtcag aatagaggag
     6001 agagttggga acaatttaag ttgttgcctc cgttcttagg agaaaaacat aatggaactt
     6061 acttatgtcc cggacaaggt ttagcattaa aatcaagtaa cagattgatt tttgcaacat
     6121 atactagtgg agaactaacc tatctcattt ctgatgatag tggtcaaaca tggaagaaat
     6181 cctcagcttc aattccgttt aaaaatgcaa cagcagaagc acaaatggtt gaactgagag
     6241 atggtgtgat tagaacattc tttagaacca ctacaggtaa gatagcttat atgactagta
     6301 gagattctgg agaaacatgg tcgaaagttt cgtatattga tggaatccaa caaacttcat
     6361 atggcacaca agtatctgca attaaatact ctcaattaat tgatggaaaa gaagcagtca
     6421 ttttgagtac accaaattct agaagtggcc gtaagggagg tcaattagtt gttggtttag
     6481 tcaataaaga agatgatagt attgattgga aataccacta tgatattgat ttgccttcgt
     6541 atggttatgc ctattctgcg attacagaat tgccaaatca tcacataggt gtgctgtttg
     6601 aaaaatatga ttcgtggtcg agaaatgaat tgcatttaag caatgtagtt cagtatatag
     6661 atttggaaat taatgattta acaaaataaa ggagaaaaaa catggttaaa tacggtgttg
     6721 ttggagcagg gtattttgga gctgaattgg ctcgctacat gcaaaagaat gatggagcag
     6781 agattactct tctctatgat ccagataatg cagaggcgat tgcagaagaa ttgggagcaa
     6841 aagtagcaag ttccttagat gagttggttt ctagcgatga agtagattgt gttatcgtcg
     6901 caactccaaa taatcttcat aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg
     6961 ttttctgtga aaaaccaatt gcgctttctt atcaagattg tcgcgagatg gtagatgcgt
     7021 gtaaagaaaa caatgtaacc tttatggcag gacatattat gaatttcttt aatggtgttc
     7081 atcatgcaaa agaactcatt aatcaaggag ttatcggaga cgttctatat tgtcatacag
     7141 ctcgtaatgg ttgggaagaa caacaaccgt cagtatcatg gaaaaaaatt cgtgaaaaat
     7201 caggtggtca cttgtatcac cacatccatg aattggattg cgttcaattc cttatggggg
     7261 gcatgcctga aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg
     7321 gtgatgaaga tgatatgatt tttgtcaata tggaattttc taataagcgt tttgccttgt
     7381 tagaatgggg ttcagcttat cgttggggtg aacattatgt cttaatccaa ggaagcaaag
     7441 gtgccatccg cttagactta ttcaactgta aaggaactct taagctagat gggcaagaaa
     7501 gctatttctt gattcacgaa tcgcaagaag aagatgatga tcggactcgt atctatcata
     7561 gtacagagat ggatggagca attgcttatg gtaaaccagg taaacgtact ccattatggc
     7621 tatcatctgt cattgataaa gaaatgcgct atctgcatga gattatggaa ggagccccag
     7681 tatcagaaga atttgcaaaa cttttgacag gtgaagctgc cctagaagca attgctactg
     7741 cagatgcttg tacccagtct atgtttgaag atcgcaaagt aaaattgtca gaaattgtaa
     7801 aataaatttt ggtattctcc tatttatagg tcgacttgct cctctgaaag tacttttaga
     7861 ggagctgttt gactttgcta gtttttgaaa ctgaaatcta ttatactaca aactattgaa
     7921 agcgttttaa ttttaaggta taataatctc atagaaataa agaaaaggag gaaagaggat
     7981 gccacagatt agcaaagaag ccttgattga gcaaatcaaa gatggaatca tcgtttcttg
     8041 tcaggctctt cctcatgaac cgctttatac agaagcggga ggggtgattc ccttgctggt
     8101 caaagcggct gagcaaggtg gagcagtcgg tatccgagca aacagtgttc gcgatatcaa
     8161 ggaaattaag gaagtcacta aacttccaat cattgggatt atcaaacgtg attatccacc
     8221 tcaggaaccc ttcatcacgg ctactatgaa agaagttgat gaattggcag aactggacat
     8281 cgaggtgatt gctctggatt gtaccaagcg tgaacgctac gatggtttgg aaattcaaga
     8341 gttcattcgt caggttaagg agaaatatcc taatcagctt ttgatggctg atactagtat
     8401 cttcgaagaa gggctagcag ctgtagaagc aggaattgac tttgtcggaa caaccttatc
     8461 aggctacaca tcctacagtc caaaagtaga cggtccagat tttgaattga ttaagaaact
     8521 ctgtgatgcc ggtgtagatg tcattgcaga aggaaaaatt catacaccag aacaagccaa
     8581 acaaatcctt gaatatggag tgcgaggcat cgttgttggt ggcgccatta ctagaccaaa
     8641 agagattaca gaacgcttcg ttgctagtct taaataagat gtgagaggga gttttatgtt
     8701 taaagtttta caaaaagttg gaaaagcttt tatgttacct atagctatac ttcctgcagc
     8761 aggtctactt ttggggattg gtggtgcact ttcaaaccca accacgatag caacttatcc
     8821 aatactagac aatagtattt ttcaatcaat attccaagta atgagctctg caggagaggt
     8881 tgtattcagt aatttgtcac tacttctctg tgtgggatta tgtattggct tagcgaaacg
     8941 agataaagga accgctgcgt tagcaggagt aactggttac ttagttatga ctgcaacgat
     9001 caaagctttg gtaaaacttt ttatggcaga aggatctgca attgatactg gagttattgg
     9061 agcattagtt gtcggaatag ttgccgtata tttgcacaac cgatataaca atattcaatt
     9121 accttccgct ttaggattct ttggaggttc acgcttcgtt cctattgtta catcgttctc
     9181 ttctatcttg attggctttg tcttctttgt tatttggcca cctttccaac aacttcttgt
     9241 ttctacaggt ggatatattt ctcaggcggg tccaattgga acttttctat atggattttt
     9301 aatgagactt tctggagcag taggcttaca tcatataatt taccctatgt tttggtatac
     9361 tgaacttggt ggtgttgaaa ctgttgcagg acaaacagtg gttggagctc aaaaaatatt
     9421 ttttgctcaa ttagccgatc cggcccattc tggattattt acagaaggaa caaggttttt
     9481 tgcaggtcgt ttctcaacaa tgatgttcgg tttaccggct gcctgtttag cgatgtacca
     9541 tagtgttcct aaaaatcgtc gtaaaaaata cgcgggtttg ttttttggag ttgctttaac
     9601 atcttttatt accggtatta cagaaccaat tgaatttatg tttctattcg tcagtccggt
     9661 tctatatgtt gttcacgcat tccttgatgg tgttagcttc tttattgcag acgtcttaaa
     9721 tatttcaata ggaaacacat tttcaggagg tgtaatcgat ttcactttat ttggaatttt
     9781 gcaggggaac gctaagacga attgggttct tcagattcca attggactta tttggagtgt
     9841 tttgtattat attattttta gatggttcat tactcaattc aacgttctaa cgccaggacg
     9901 aggagaagaa gtagattcta aagaaatttc tgaatccgca gattcaactt caaatactgc
     9961 agattattta aaacaggata gcctacaaat tatcagagcc ttgggtggat caaataatat
    10021 agaagatgta gatgcttgtg tgacacgttt acgtgtagct gtaaaagaag ttaatcaagt
    10081 tgataaagca cttttaaaac aaattggtgc agttgatgtc ttagaagtga agggtggcat
    10141 tcaagcaatc tatggagcaa aagcaatctt atataaaaat agtattaatg aaattttagg
    10201 tgtagatgat taagtactta ctgacttaat aaaaaacaga ggagagtgat ggatgagtag
    10261 gatgaaatga aatcgtatac aagaaataaa gaactcatta tccaagttgg atacgcttat
    10321 tacataggag aatacaaatg aaatttagaa aattagcttg tacagtactt gcgggtgctg
    10381 tggttcttgg tcttgctgct tgtggcaatt ctggcggaag taaagatgct gccaaatcag
    10441 gtggtgacgg tgccaaaaca gaaatcactt ggtgggcatt cccagtattt acccaagaaa
    10501 aaactggtga cggtgttgga acttatgaaa aatcaatcat cgaagcgttt gaaaaagcaa
    10561 acccagatat aaaagtgaaa ttggaaacca tcgacttcaa gtcaggtcct gaaaaaatca
    10621 caacagccat cgaagcagga acagctccag acgtactctt tgatgcacca ggacgtatca
    10681 tccaatacgg taaaaacggt aaattggctg agttgaacga cctcttcaca gatgaatttg
    10741 ttaaagatgt caacaatgaa aacatcgtac aagcaagtaa agctggagac aaggcttata
    10801 tgtatccgat tagttctgcc ccattctaca tggcaatgaa caagaaaatg ttagaagatg
    10861 ctggagtagc aaaccttgta aaagaaggtt ggacaactga tgattttgaa aaagtattga
    10921 aagcacttaa agacaagggt tacacaccag gttcattgtt cagttctggt caagggggag
    10981 accaaggaac acgtgccttt atctctaacc tttatagcgg ttctgtaaca aatgaaaaag
    11041 ttagcaaata tacaactgat gatcctaaat tcgtcaaagg tcttgaaaaa gcaactagct
    11101 ggattaaaga caatttgatc aataatggtt cacaatttga cggtggggca gatatccaaa
    11161 actttgccaa cggtcaaaca tcttacacaa tcctttgggc accagctcaa aatggtatcc
    11221 aagctaaact tttagaagca agtaaggtag aagtggtaga agtaccattc ccatcagacg
    11281 aaggtaagcc agctcttgaa taccttgtaa acgggtttgc agtattcaac aataaagacg
    11341 acaagaaagt cgctgcatct aagaaattca tccagtttat cgcagatgac aaggagtggg
    11401 gacctaaaga cgtagttcgt acaggtgctt tcccagtccg tacttcattt ggaaaacttt
    11461 atgaagacaa acgcatggaa acaatcagcg gctggactca atactactca ccatactaca
    11521 acactattga tggatttgct gaaatgagaa cactttggtt cccaatgttg caatctgtat
    11581 caaatggtga cgaaaaacca gcagatgctt tgaaagcctt cactgaaaaa gcgaacgaaa
    11641 caatcaaaaa agctatgaaa caatagtcct tagttattct ataaaaagta gttttttaaa
    11701 gaacctaaga gtgtataccc ccttttccct ctacacagat agtgtaagaa aagggggctt
    11761 ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa gttcttacat aagcgaatca
    11821 taaaaaattt cattttgatt ttaaaacagt tcaagaaagt caaaaaatta ttctatttga
    11881 aagagaggtg ccgactgtga aagtcaataa aatccgtatg cgggaaacag tgatttccta
    11941 cgctttccta gcaccagtat tattcttctt tgtcatcttt gtgttggctc cgatggtgat
    12001 gggcttcatt acaagtttct ttaactactc aatgactaaa tttgagtttg taggcttgga
    12061 taactatatc cgtatgttta aagatcctgt ctttacaaaa tctctgatta acacagttat
    12121 tttggttatt ggatctgtac cagttgttgt tctattctca ctctttgtag catctcagac
    12181 ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc gtcttcttcc ttcctgttgt
    12241 aacgggtagt gttgccgtga cagttgtttg gaaatggatt tatgacccac tatcagggat
    12301 tctaaacttt gtccttaagt caagccacat catcagccaa aacatttctt ggttgggaga
    12361 taaaaactgg gcattgatgg cgattatgat tattctcttg accacttcag ttggtcagcc
    12421 catcatcctt tatatcgctg ccatggggaa tattgacaat tcactggttg aagcggcgcg
    12481 tgttgatggt gcaactgagt ttcaagtttt ttggaagatt aaatggccaa gccttcttcc
    12541 aacaactctt tatattgcaa tcatcacaac aattaactca ttccagtgtt tcgccttgat
    12601 tcagcttttg acatctggtg gtccaaacta ctcaacaagt accttgatgt actaccttta
    12661 cgaaaaagcc ttccaattga cagaatacgg ctatgccaac acaattggtg tcttcttggc
    12721 agtcatgatt gctatcgtaa gctttgttca atttaaagta cttggaaacg acgtagaata
    12781 ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa ccattaacag cctttactgt
    12841 tatttcaaca atcattttgc tcttgttgac tgtgctgttc atctttccat tctactggat
    12901 tttgacaggg gcattcaaat cacaacctga tacaattgtt attcctcctc agtggttccc
    12961 taaaatgcca accatggaaa acttccaaca actcatggtg cagaaccctg ccttgcaatg
    13021 gatgtggaac tcagtattta tctcattggt aaccatgttc ttagtctgtg caacctcatc
    13081 tctagcaggt tatgtattgg ctaaaaaacg tttctatggt caacgcattc tatttgctat
    13141 ctttatcgct gctatggcac ttccaaaaca agttgtcctt gtaccattgg tacgtatcgt
    13201 caacttcatg ggaatccacg atactctctg ggcagttatc ttgcctttga ttggatggcc
    13261 attcggtgtc ttcctcatga aacagttcag tgaaaatatc cctacagagt tgcttgaatc
    13321 agctaaaatc gacggttgtg gtgagattcg taccttctgg agtgtagcct tcccgattgt
    13381 gaaaccaggg tttgcagccc ttgcaatctt taccttcatc aatacttgga atgactactt
    13441 catgcaattg gtaatgttga cttcacgtaa caatttgacc atctcacttg gggttgcgac
    13501 catgcaggct gaaatggcaa ccaactatgg tttgattatg gcaggagctg cccttgctgc
    13561 tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc ttcacacagg gtattactat
    13621 gggagcggtc aaaggataat actctgcgaa aatcgaatgc aaactacgtc agcttcacct
    13681 tgccatactt aagtattgcc tgtggttagc ttcctagttt gttcttcaat tttcattgag
    13741 tataggaaaa tcaatctatc aagatacaga agtatatttt atagatttag agaatataga
    13801 agttataagt gtctacaaaa tggagggtat gcagttactt tatgaagttt tgtcagacac
    13861 ttatcaactt aagaatggtt ttagttaact atcagaaacg aaggaaagag tatgattttt
    13921 gacgatttga aaaacatcac cttttacaaa gggattcatc ccaatttaga caaggctatc
    13981 gactacctct accaacatcg taaagattca ttcgaattag gaaagtatga gattgatgga
    14041 gataaagtct ttctagttgt tcaggaaaat gtcctcaatc aagttgagaa taatcaattt
    14101 gaacaccata agaactatgc agatttgcat ttgctgatag aagggcatga atattcgagc
    14161 tacggttcac gtatcaaaga cgaggcagta gcattcgacg aagcgagtga cattggcttt
    14221 gttcattgtt atgaacacta cccactctta ttgggttatc acaattttgc gattttcttc
    14281 ccaggtgagc cacatcagcc aaatggttat gcaggcatgg aagaaaaggt tcgaaaatat
    14341 ctctttaaaa tcttgattga ttaaaaatag gatgaattgt ttttttgtaa agctttgata
    14401 atactctacc atgaaattga tctttgtgag gtagagaaat gagaataaaa tatttaaaaa
    14461 ttggtatctt ctaagtatgc tgcaagagct agtttcttgg atggacaggg aattacagtt
    14521 gatgagatgg cttggataat taggggcatt gtgaatgcat tgattggtag atacataaaa
    14581 ttaggtgctt atgcggctaa gtatggtatt agtatggcac gctcgatctt aagtagggca
    14641 gctgcaactg cagcagcaag agtaggatta tcgaccaaga tttctggatg gattttacga
    14701 gtagctgtga atgtagctga tgtatatggt aattttgcct acaatattgc tgcagcttgg
    14761 gatgcacatg ataaaatccc taacaatggt cgtataaact tttaaaatgc gagaatgaaa
    14821 gcactttgta tttttttatt gaatatgtta gcttggacag tgcttgcaat gataattcgt
    14881 ggagggctag atggatttaa tgagcatact tggagtacta ttttaattgc ttcgctgttc
    14941 ggggtatatg attataagcc catagataaa aatagaaaaa agtccaaaag aaaaaagaaa
    15001 aaatagattt gttcatggta gggacttatg aaagctttac tgacaaaaaa gaaaacagtt
    15061 tacaaagaaa aatgatggag gagcaaacat ggcacaaaaa ggagtaagcc ttatcaaggc
    15121 agcatttgat acagacaact ttctcatgcg ttttagtgag aaagtcttgg acatcgtgac
    15181 agccaatctt ctttttgtcg tctcttgttt gcccatcgtg acgattggag tggctaaaat
    15241 cagcctctac gagaccatgt tcgaagttaa gaagagcaga cgggtgcctg tttttaaaat
    15301 ctatctaaga tctttcaagc aaaatctgaa actaggtctt cagctgggtt taatggagtt
    15361 aggaattgtg tttcttaccc tttcagatct ctatcttttc tggggtcaaa cagctctgcc
    15421 cttccaattg ctgaaagcca tttgtttagg tattctgatt tttcttacta tcgtgatgct
    15481 ggctagttac cctatcgcgg cacgttatga cctatcttgg aaagaaattc ttcaaaaagg
    15541 attgatgttg gctagtttta actttccttg gttcttcctc atgttagcca ttcttgtcct
    15601 cattgtgatg gttctttatc tgtccgcctt cagtctactc ttaggtggct cagtcttcct
    15661 actttttggg tttggactat tggtctttat ccagactgga ttgatggaga aaattttcgc
    15721 aaaataccaa taggagcttt atttctgaaa ctactttcaa aggctccaaa cgctattcta
    15781 taagcgagaa actaaaatct aagtgtctat aagatattga aagccttttc gggaaagtgt
    15841 atactaaaga agtaaagaaa aatctgcttt agcagaaaat aaaaataata ggagaaaatc
    15901 tatgtcagat ttgaaaaaat acgaaggtgt cattccagcc ttctacgcat gttatgatga
    15961 tcaaggagaa gtaagcccag aacgtacgcg tgccttggtt caatacttca ttgataaagg
    16021 tgttcaaggt ctttatgtca atggttcttc tggtgaatgt atctaccaaa gcgttgaaga
    16081 tcgcaagttg attttggaag aagtcatggc ggtagccaaa ggtaaattga ccatcattgc
    16141 tcatgttgcc tgcaacaata ctaaagacag tatggaactt gctcgccatg ctgaaagctt
    16201 gggagtagat gctattgcaa cgattccacc aatttacttc cgcttgccag aatactcagt
    16261 tgccaaatac tggaacgata tcagttctgc agctccaaac acagactacg tgatttacaa
    16321 cattcctcaa ttggcagggg ttgctttgac tccaagcctt tacacagaaa tgttgaaaaa
    16381 tcctcgtgtt atcggtgtta agaactcttc tatgccagtt caagatatcc aaacctttgt
    16441 cagccttggt ggggaagacc atatcgtctt taacggtcca gatgaacagt tcctaggtgg
    16501 ccgcctcatg ggtgctaagg ctggtatcgg tggtacttat ggtgctatgc cagaactctt
    16561 cttgaaactc aatcagttga ttgcggataa ggacctagaa acagcgcgtg aattgcagta
    16621 tgctatcaac gcaatcattg gtaaactcac ttctgctcat ggaaatatgt acggtgtcat
    16681 taaagaagtt ttgaaaatca atgaaggctt gaatattgga tctgttcgtt caccattgac
    16741 accagtgact gaagaagatc gtccagttgt agaagcggct gctgccttga ttcgtgaaac
    16801 caaggagcgc ttcctctaat ctaaaaggag gtatttatga catactacgt tgcaattgat
    16861 atcggtggaa ccaacatcaa gtatggtttg gttgatcaag aggggcaact tcttgaatcg
    16921 catgaaatgc caactgaggc gcataagggt ggacctcata tcttacaaaa gaccaaagat
    16981 atcgtagcta gttatttaga aaaaggccta gtagcaggtg ttgccatatc ttctgctggg
    17041 atggtggatc cggataaggg tgagattttc tatgctgggc cgcaaatccc taactacgca
    17101 ggcacccagt tcaaaaagga aatcgaagaa agctttacta ttccttgtga gattgaaaat
    17161 gatgtcaact gtgcaggtct tgctgaggca gtatctggtt caggcaaggg agcaagtatg
    17221 acactttgct tgaccattgg aacaggtatc ggtggttgct tgattatgga taggaaagtc
    17281 ttccatggtt ttagcaattc agcctgtgaa gtcgggtata tgcatatgca ggatggagct
    17341 tttcaagact tggcttctac aacagcttta gtgaaatatg tagctgaagc ccatggagaa
    17401 gatgttgatc agtggaatgg ccgtagaatt ttcaaagaag ccactgaagg aaacaaaatc
    17461 tgcatggaag gtattgaccg tatggttgac tatctaggaa aaggtctggc aaatatttgc
    17521 tacgttgcca atccagaagt ggttattctt ggtggtggta tcatggggca agaggctatc
    17581 ctcaaaccta agattcgcac agccttgaaa gaggctttgg taccaagttt agcagaaaaa
    17641 acacgattag aatttgccca tcaccaaaat acagcaggga tgttgggtgc atattatcat
    17701 tttaagacaa aacaatccta gtttggctca gccaaactag gattttctta cacgtttttg
    17761 tctacgatag ccgttgagtt ttttattttc ccagtagcta ttaaagattt tttccttgct
    17821 ttcgcgattg atttccaaaa agtaggcata aatcaaatcg ataaagaaga gcataggaag
    17881 ttgagcggat attcgttgga tataggaggg ttggctgtgg gtggctacaa gaacagtctc
    17941 tgtataggtc tggctatttt tattgggaac acttgtaaag agtacagtct ttgcccccat
    18001 ctccttggca tctaatagac tatctaaaat agaaggagtt gagcctgaaa gtgagaagcc
    18061 cagtactaga caattttcat ccatgatgct ggttgtccag gcaaagccgt cttggtctgt
    18121 caaagcttcg cagaccacgc ctagtcgcat aaaacgtaat ttcatttcac gggcgacgag
    18181 accagaactc cctgttccaa agaagtagat acgctcagca tcttcgatta gctgggcaat
    18241 tcgttctagt tggatttcgt caatcaagtc ttgtgtttgt tccctcatat tgctataact
    18301 tctgaggact cgtttggtca gtggactgtg cttggagact tggttggctt gattttctgc
    18361 ctgatgttgg tattggaaaa taaattctcg gtagccagta aagccacact ttttagcaaa
    18421 gcgggtcaaa gcagcttgag aaatatgtaa tttttgggtg acttgttgag aagataaatc
    18481 atctgtaatc gtttcagctt gcaaaaaata gcgagcgatt tcttgctcta ggtctgtcat
    18541 ttcttcaaaa tgtgaatcaa tgatagttgc gatatctggt ttgtccatag ggaaagctcc
    18601 tttacatgag tcatactgga agactagatc agggaatagt cacacttcat tataacacat
    18661 aatataagga tagataaata aaaacgcatt tctgttttaa aaacgaaaaa atcgaaaaag
    18721 cttctctctt ttccataatt ttctactcaa attgtggtac aattaagagt aagattttaa
    18781 gttagaaatg agactgattt gtatgagaaa atttaacagc cattcgattc cgattcggct
    18841 taatttattg ttttcaatcg tcattttact ctttatgacc attattggtc gtttgttgta
    18901 tatgcaggtt ttgaacaagg atttttacga aaaaaagcta gcctcagcta gtcagaccaa
    18961 gattacaagc agttcagccc gtggggaaat ttatgatgct agtggaaaac ctttggtaga
    19021 aaatacgtta aagcaggttg tttcctttac gcgtagcaat aaaatgacgg ctacagactt
    19081 aaaagaaaca gctaaaaagt tactgactta tgtgagcatc agttctccaa atttgacaga
    19141 acgccagctg gcggattact atttggctga tcctgaaatc tataaaaaaa cagtggaagc
    19201 tctcccaagc gagaaacgct tggattcaga tggaaatcgt ctatccgaat cagaactgta
    19261 taacaatgcg gtcgatagtg tccaaacaag tcaactaaac tatacagagg atgaaaagaa
    19321 agaaatctat ctttttagtc agttaaatgc tgttggaaac tttgcgacag gaaccattgc
    19381 tacagatcct ctaaatgatt ctcaggtggc tgttattgcc tctatttcaa aggagatgcc
    19441 tggcattagt atttctactt cttgggatag aaaggttttg gaaacttccc tttcttctat
    19501 agttgggagt gtatccagtg aaaaagctgg tctcccagcg gaagaagcag aagcctatct
    19561 taaaaaaggc tattctctaa atgaccgtgt aggaacctcc tatttggaaa agcaatatga
    19621 agagacctta caaggaaaac gatcggtaaa agaaatccat ctggataaat atggcaatat
    19681 ggaaagcgtg gatacaattg aggaaggtag taagggaaac aatatcaaac tgaccattga
    19741 tttggccttc caagatagcg tggatgcttt gctgaaaagt tatttcaatt ctgagctaga
    19801 aaatggtgga gccaagtatt ctgaaggtgt ctatgcagtc gcccttaacc caaaaacagg
    19861 tgcggttttg tctatgtcag ggattaaaca tgacttgaaa acaggagagt tgacgcctga
    19921 ttccttggga acggtaacca atgtctttgt tccaggttcg gttgtcaagg cggcgaccat
    19981 cagctcaggt tgggaaaatg gagtcttgtc aggaaaccag accttgacag accagtccat
    20041 tgtcttccaa ggttcagctc ccatcaattc ttggtatact caggcttacg gttcattccc
    20101 tatcacagcg gtccaagctc tggagtattc atcaaatacc tatatggtcc aaacagcctt
    20161 aggtcttatg gggcaaacct atcaacccaa tatgtttgtc ggcaccagca atctagagtc
    20221 tgctatggag aaactgcgtt caacctttgg cgaatatggc ttgggtactg cgacaggaat
    20281 tgacctacca gatgaatcta ctggatttgt tcccaaagag tatagctttg ctaattacat
    20341 tactaatgcc tttgggcagt ttgataacta tacgccgatg cagttggctc agtatgtagc
    20401 aactattgca aatgatggtg ttcgtgtggc tcctcgtatt gttgaaggca tttatggtaa
    20461 taatgataag ggaggactgg gtgacttgat tcagcaactg caaccgacag agatgaataa
    20521 ggtcaatata tccgactccg atatgagcat cttgcaccaa ggtttttatc aggttgccca
    20581 tggtactagt gaattgacaa ctggacgtgc cttttcaaat ggtgccttgg tatccattag
    20641 cggaaaaaca ggtacagccg aaagctatgt ggcagatggt cagcaagcaa ccaataccaa
    20701 tgcggtggcc tatgccccat ctgataatcc ccaaatcgct gtcgcagtgg tctttcctca
    20761 taataccaat ctaacaaatg gtgtaggacc ttccattgca cgtgacatta tcaatctgta
    20821 tcaaaaatac catccaatga actagaaagg aaattatgct ttatccaaca cctattgcca
    20881 agttgattga cagttattct aagttaccag gtatcgggat taagacggct acgcgtctgg
    20941 ccttttatac gattgggatg tctgctgatg atgtcaatga atttgcaaaa aatctccttt
    21001 ctgctaagag agaattgaca tattgttcta tttgtggacg tttgacagac gacgatcctt
    21061 gttctatctg tactgatccg actcgtgacc agacaacaat tttagttctt gaggatagta
    21121 gagatgtggc agccatggaa aatatccaag aataccatgg actctatcat gtccttcatg
    21181 gcctcatttc tcctatgaat ggtatcagtc cggacgatat caatctcaag agccttatga
    21241 ctcgtcttat ggatagtgag gtttcagaag tgattgtggc gactaatgct acagcggatg
    21301 gtgaagcgac ttccatgtat ctttcacgtt tgctcaagcc ggctggtatc aaggttacgc
    21361 gtctagcacg aggtctcgct gtgggagcgg acattgagta tgcggacgaa gtgacactct
    21421 tacgagccat tgaaaatcgg acagagttgt aagtgtaggc aaatttacga actccattca
    21481 tttataaaaa atcaaagagg ctggaaatcg ttcctatcgg cctctttttg tatagtgtga
    21541 tgagtaggat caggttcaag ttttaaaaaa ccaagcaaat atgatatact aaagagcgag
    21601 tattctagta gaattaggac aaataatatg aaacaaacga ttattctttt atatggtgga
    21661 cggagtgcgg aacgcgaagt ctctgtcctt tcagctgaga gtgtcatgcg tgcggtcgat
    21721 tacgaccgct tcacagtcaa gactttcttt atcagtcagt caggtgactt tatcaaaaca
    21781 caggaattta gtcatgctcc ggggcaagaa gaccgtctca tgaccaatga aaccattgat
    21841 tgggataaga aagttgcacc aagtgctatc tacgaagaag gtgcagtggt ctttccagtc
    21901 cttcacgggc caatgggaga agatggctct gttcaaggat tcttggaagt tttgaaaatg
    21961 ccttacgttg gttgcaacat tttgtcatca agtcttgcca tggataaaat cacgactaag
    22021 cgtgttctgg aatctgctgg tattgcccaa gttccttatg tggctatcgt tgaaggcgat
    22081 gatgtgactg ctaaaatcgc tgaagtggaa gaaaaattgg cttatccagt cttcactaag
    22141 ccgtcaaaca tggggtctag tgtcggtatt tctaagtctg aaaaccaaga agaactccgt
    22201 caagccttag aacttgcctt ccgatatgat agccgtgtct tggttgagca aggagtgaat
    22261 gcccgtgaaa ttgaggttgg cctcttgggt aactacgatg tcaagagcac gctaccagga
    22321 gaagttgtca aggacgttgc cttttatgac tacgatgcca agtatattga taacaagatt
    22381 actatggata ttcctgccaa aatcagtgat gatgtggtgg ctgtcatgcg tcaaaatgca
    22441 gaaacagcct tccgtgccat tggtggcctt ggtctatctc gttgcgattt cttctataca
    22501 gataagggag agatttttct caacgagctc aataccatgc caggtttcac ccagtggtct
    22561 atgtacccac tactttggga caatatgggg atcagctacc cagaactaat cgagcgtttg
    22621 gttgaccttg ccaaggaaag ttttgacaag cgcgaagcgc atttgatata aaatgaaaga
    22681 gagggtagaa gccagaacca tcactgcaag gtgactagag ttctcggact tcagcccttt
    22741 ttaaaggagt agaaatgaaa ttaacaatcc atgaaattgc ccaagttgtt ggagccaaaa
    22801 atgatatcag tatctttgag gacacccagt tagaaaaagc tgagtttgat agtcgtttga
    22861 ttggaactgg agatttattt gtgccactta aaggtgcgcg tgatggccat gactttattg
    22921 aaacagcctt tgaaaatggt gcagcagtaa ccttgtctga gaaagaggtc tcaaatcatc
    22981 cttacattct agtagatgat gttttgacag cctttcaatc cctagcatcc tactatcttg
    23041 aaaaaacgac tgttgatgtc tttgctgtta caggttcaaa tggcaagaca acgactaagg
    23101 atatgttggc gcatttactg tcaacaagat acaagaccta caaaacacaa ggcaattaca
    23161 ataacgagat tggccttcct tacacagttc ttcatatgcc tgaagggaca gaaaagttgg
    23221 tcttggagat ggggcaggat cacttgggag atattcatct cttgtctgaa ctggctcgtc
    23281 caaaaacagc catcgtgacc ttggttggag aagctcattt ggcctttttc aaagatcgtt
    23341 ctgagattgc taaaggaaaa atgcaaattg cggacggaat ggcttcaggt tccttgcttt
    23401 tagcgccggc tgaccctatc gtagaggact atttgccaac tgataaaaaa gtggttcgtt
    23461 ttgggcaagg ggcagagctg gaaattactg acttggttga gcgcaaagat agtctgacct
    23521 tcaaggccaa tttcttagag caagcccttg atttgccagt aactggtaag tacaatgcta
    23581 ccaatgctat gattgcatcc tatgttgccc tacaagaagg agtttcagag gagcaaatcc
    23641 gtttggcctt ccaaggtctt gaattgacgc gtaatcgtac tgagtggaag aaagcagcca
    23701 atggagcaga tatcctgtca gacgtatata atgccaatcc aactgctatg aagctgattt
    23761 tagagacttt ctctgccatt ccagccaatg aaggtggcaa gaaaattgca gtgttggcgg
    23821 atatgaagga gcttggtgac cagtctattc aactccataa ccagatgatt ttgagccttt
    23881 cgccagatgt gcttgatacc gttattttct atggagaaga cattgctgaa ttagcccaat
    23941 tggccagtca aatgttccca attggccacg tttactactt caagaaaaca gaagaccaag
    24001 accaatttga agacctagtc aagcaggtca aggaaagcct cagtgccaat gatcaaatct
    24061 tgctcaaggg ctctaactct atgaacctag ccatgttggt agaaagttta gaaaatgaaa
    24121 ccaagtgatt ttgttaagta tctgcaaaga atgattgccc ttacagatac tggcttaacc
    24181 tttacaaaag atccttttga ccgtgagcgc tacgaggact tgcgaagtct gttatctgaa
    24241 atgttgaatc agggatcaga cctggatgca gaagaagtag cagaagtctt gaaaccaact
    24301 tcagcttatg cgactccctt aatggacgtc cgtgcttgga ttgttgagga tgagaagatt
    24361 tgtctggtta ggggacaagg agaggatagt tgggctttgc caggtggctt tggtgaagtc
    24421 ggctattctc caactgaaaa tattctcaag gaaattgaag aagaaaccgg ttttaaagcc
    24481 aaagttgaaa gactgctagc tgtttttgat accaatcgtt tccaactaca gagcaaacaa
    24541 tatgcaaagt ttgtttttga atgtaagctt ctcgatggac aattccaaga aaatcaagaa
    24601 atcgctgacc ttcaattttt tgcaattgac caactgccga atttatctga aaaacgcatt
    24661 accaaggagc aaatagagct tctttggcag gtttatcaag gtcagaggga gcaatatctt
    24721 gactaagaag atgattatcg tatttctaaa ttcatttttc ttaagtagca tggtataata
    24781 aaatgcagga aaattttgaa tcatgaggaa gactagatga atttatggga tattttcttt
    24841 acgactcagg caaccgagcc gcccaaattt gacctttttt ggtatgttag cctatttacg
    24901 ctcttagcct taacctttta tacagcccat cgctatcgtg aaaagaaggt ttaccaacga
    24961 tttttccaaa tcttgcagac tgttcagtta atccttcttt atggttggta ctgggtcaat
    25021 catatgccac tgtcagaaag cctacccttt taccattgcc gtatggctat gtttgtggta
    25081 ctcttgcttc ctggtcagtc caaatataaa caatactttg cattattggg aacatttggg
    25141 acattagcag cctttgttta tccagtgcca gatgcttacc cttttccaca tatcaccatt
    25201 ctatccttta tctttggtca tttagcactc ttggggaact ctctagttta tctattgaga
    25261 cagtataatg cgcgattgct ggatgtgaag ggaatttttc tcatgacctt tgccctaaat
    25321 gccttgattt ttgtggtcaa tttggtgaca ggtggcgatt acggattttt gacaaaaccg
    25381 ccattggttg gggatcacgg tctagtagct aattatttac ttgtttcaat tgtgctggta
    25441 gctactatca gtttgactaa gaaaatctta gaattctttt tagctcaaga agcagaaaaa
    25501 atgattgcaa aggaagctta acacagagct ttcttttttg ctcttagaga gtttttacaa
    25561 gcagcttata aaataagaat ttctgaatag acaaactcaa aaaatggctg ggaaatttag
    25621 gaaaaaagca agcacgatta aattttttgt gttataatat tttgtgaata gctatgccta
    25681 tgtttagcta tggaataata cgaagtgcga aacttggaag atagagagga agcgatgtaa
    25741 tggctagaga aggctttttt acaggtctag atattggaac aagctctgtc aaggtgcttg
    25801 tggccgagca gagaactggt gaattaaatg taattggcgt gagtaatgcc aaaagtaaag
    25861 gtgtaaagga tggaattatt gttgatattg atgcagcagc aactgctatc aagtcagcca
    25921 tttcccaagc ggaagaaaag gcaggcattt cgattaaatc agtaaatgtc ggcttgcctg
    25981 gtaatctttt gcaggtagaa ccaactcagg ggatgattcc agtaacatct gatactaagg
    26041 aaattacgga tcaagatgtt gaaaatgttg tcaaatcagc tttgacaaag agtatgacac
    26101 ctgaccgtga agtcattacc tttattcctg aagaatttat tgtggatggt ttccaaggga
    26161 ttcgtgaccc acgtggcatg atgggggttc gccttgaaat gcgtggtttg ctttatacag
    26221 gacctcgtac tatcttgcac aatttgcgta agacggttga gcgtgcaggt gttcaggttg
    26281 aaaatgttat catttcacca ctagcaatgg ttcagtctgt tttgaacgaa ggggaacgtg
    26341 aatttggtgc tacagtgatt gatatggggg caggtcaaac gactgtcgct acaatccgta
    26401 atcaagaact ccagttcaca catattctcc aagaaggtgg agattatgta actaaagata
    26461 tctccaaggt tttgaaaacc tctcgcaaat tagcggaagg cttgaaactg aattacgggg
    26521 aagcctatcc gcctcttgca agcaaagaaa ccttccaagt agaggttatt ggagaagtag
    26581 aagcagtcga agtgacggaa gcctacttgt cagaaattat ttctgcacga atcaagcaca
    26641 tccttgaaca aatcaagcaa gaattagata gaaggcgtct attggacctc cctggtggta
    26701 ttgtcttaat cggtgggaat gccattttac caggtatggt tgagcttgct caggaagtct
    26761 ttggcgtccg tgtcaagctt tatgttccaa atcaagttgg tatccgtaat ccagcctttg
    26821 cgcatgtgat tagtttatca gaatttgcgg gtcaattaac agaagttaat cttttggctc
    26881 agggagcgat aaaaggtgag aatgacttaa gtcatcagcc aattagtttt ggtgggatgc
    26941 tgcaaaaaac agctcagttt gtacaatcaa cgcctgttca accagctcct gctccagaag
    27001 tagagccggt ggcgcctaca gaaccaatgg cggatttcca acaagcttca caaaataaac
    27061 cgaaattagc agatcgtttc cgtggcttga tcggaagcat gtttgacgaa taaagaggaa
    27121 aaataaatta tgacattttc atttgataca gctgctgctc aaggggcagt gattaaagta
    27181 attggtgtcg gtggaggtgg tggcaatgcc atcaaccgta tggtcgacga aggtgttaca
    27241 ggcgtagaat ttatcgcagc aaacacagat gtacaagcat tgagtagtac aaaagctgag
    27301 actgttattc agttgggacc taaattgact cgtggtttgg gtgcaggagg tcaacctgag
    27361 gttggtcgta aagccgctga agaaagcgaa gaaacactga cggaagctat tagtggtgcc
    27421 gatatggtct tcatcactgc tggtatggga ggaggctctg gaactggagc tgctcctgtt
    27481 attgctcgta tcgccaaaga tttaggtgcg cttacagttg gtgttgtaac acgtcccttt
    27541 ggttttgaag gaagtaagcg tggacaattt gctgtagaag gaatcaatca acttcgtgag
    27601 catgtagaca ctctattgat tatctcaaac aacaatttgc ttgaaattgt tgataagaaa
    27661 acaccgcttt tggaggctct tagcgaagcg gataacgttc ttcgtcaagg tgttcaaggg
    27721 attaccgatt tgattaccaa tccaggattg attaaccttg actttgccga tgtgaaaacg
    27781 gtaatggcaa acaaagggaa tgctcttatg ggtattggta tcggtagtgg agaagaacgt
    27841 gtggtagaag cggcacgtaa ggcaatctat tcaccacttc ttgaaacaac tattgacggt
    27901 gctgaggatg ttatcgtcaa cgttactggt ggtcttgact taaccttgat tgaggcagaa
    27961 gaggcttcac aaattgtgaa ccaggcagca ggtcaaggag tgaacatctg gctcggtact
    28021 tcaattgatg aaagtatgcg tgatgaaatt cgtgtaacag ttgtcgcaac gggtgttcgt
    28081 caagaccgcg tagaaaaggt tgtggctcca caagctagat ctgctactaa ctaccgtgag
    28141 acagtgaaac cagctcattc acatggcttt gatcgtcatt ttgatatggc agaaacagct
    28201 gaattgccaa aacaaaatcc acgtcgtttg gaaccaactc aggcatctgc ttttggtgat
    28261 tgggatcttc gccgtgaatc gattgttcgt acaacagatt cagtcgtttc tccagtcgag
    28321 cgctttgaag ccccaatttc acaagatgaa gatgaattgg atacacctcc atttttcaaa
    28381 aatcgttaag taaatgaatg taaaagaaaa tacagaactt gtttttcgag aagttgcaga
    28441 ggctagtctg agtgctcatc gagagagtgg ttcggtctct gtcattgcag ttaccaagta
    28501 tgtagatgta ccgacagcgg aagccttgct tccgctaggt gttcatcata tcggtgaaaa
    28561 tcgtgtagat aagtttctgg aaaaatatga agctttaaaa gatcgagatg tgacttggca
    28621 tttgattggt accttgcaaa gacgtaaggt gaaagatgtc attcaatacg ttgattattt
    28681 ccatgcattg gactcagtaa agctagcagg ggaaattcaa aaaagaagtg accgagtcat
    28741 caagtgtttc cttcaagtaa atatttctaa agaagaaagc aaacacggtt tttcgagaga
    28801 ggaactgctg gaaatcttgc cagagttagc cagactagat aagattgaat atgttggttt
    28861 aatgacgatg gcaccttttg aggctagcag tgagcagttg aaagagattt tcaaggcgac
    28921 ccaagattta caaagagaaa ttcaagagaa acaaattcca aatatgccta tgaccgagtt
    28981 aagtatggga atgagtcgtg attataaaga agcgattcaa ttcggttcca cttttgttcg
    29041 tataggtaca tcatttttta agtaggagag aaccatgtct ttaaaagata gattcgatag
    29101 atttatagat tattttacgg aggatgagga ttcaagtctc ccttatgaaa aaagagatga
    29161 gcctgtgttt actccagtaa attcttcaca ggaaccggct ctcccaatga atcaaccttc
    29221 acagtcggct ggtacaaaag agaacaatat caccagactt catgcaagac aacaggaatt
    29281 ggcaaatcag agtcagcgtg caacggataa ggtcattata gatgttcgtt atcctagaaa
    29341 atatgaggat gcaacagaaa ttgttgattt attggcagga aacgaaagta tcttgattga
    29401 ttttcagtat atgacagagg tgcaggctcg tcgttgtttg gactatttgg atggagcttg
    29461 tcatgtttta gctggaaatt tgaaaaaggt agcttctacc atgtatttgt tgacaccagt
    29521 gaatgttatt gtaaatgttg aagatatccg tttaccagat gaagatcaac agggtgagtt
    29581 cggttttgat atgaagcgaa atagagtacg ataatgattt ttttaattcg tatgatttat
    29641 aatgcagtgg atatttactc cctgattttg gtagccttcg ctgtcatgtc ttggtttcca
    29701 ggtgcctacg aatccagttt aggtcgttgg attgtagcgt tggtgaaacc agtgcttgct
    29761 cccttgcaac gcctgccttt acagatagcg ggtcttgatt tatctgtttg ggtcgcgatt
    29821 gttttggttc gatttttagg agaaaaccta gtgcgttttc tggcgatgat aggatgaata
    29881 aagggattta ttagcatttc tccatagaag atcgtccatt tcttgacaag ggaatggaat
    29941 ggataaagaa ggtagaagat agctatgctc cttttttaac tccttttatc aatcctcatc
    30001 aggagaagct attaaagatt ttggccaaaa cctatggtct tgcttgtagc agtagtgggg
    30061 aattcgtctc gagtgagtat gttcgagttt tattataccc agattatttc caaccagagt
    30121 tttcagattt tgaaatatct ctccaggaaa ttgtgtattc caataaattt gaacatttaa
    30181 cgcatgctaa gattttaggg acagtcatca atcaattagg gattgaacgg aaactttttg
    30241 gagatatcct agtagatgaa gaacgggcgc agattatgat taatcagcag tttcttcttc
    30301 tctttcaaga tggactaaag aaaattggtc gtatacctgt ttcgctggag gaacgtcctt
    30361 tcaccgagaa aatagataag ctagaacagt atcgagaact ggatttatct gtgtctagtt
    30421 ttcgattaga tgttctttta tcaaatgttt tgaaactatc taggaatcaa gcaaaccagt
    30481 tgattgaaaa gaaacttgtc caagtaaatt atcatgtggt agacaaatca gattacactg
    30541 ttcaagttgg agacttgatt agtgtgagaa aatttggtcg cttgagatta cttcaagata
    30601 agggacaaac gaaaaaagag aagaaaaaaa taaccgtcca gttattatta agtaagtgag
    30661 gaatagaatg ccaattacat cattagaaat aaaggacaag acttttggaa ctcgattcag
    30721 aggttttgat ccagaagaag tcgatgaatt tttagatatt gtggttcgtg attacgaaga
    30781 tcttgtgcgt gcgaatcatg ataaaaattt gcgtattaag agtttagaag agcgtttgtc
    30841 ttactttgat gaaataaaag attcattgag ccagtctgta ttgattgctc aggatacagc
    30901 tgagagagtg aaacaggcgg cgcatgaacg ttcaaacaat atcattcatc aagcagagca
    30961 agatgcgcaa cgcttgttgg aagaagctaa atataaggca aacgagattc ttcgtcaagc
    31021 aactgataat gctaagaaag tcgctgttga aacagaagaa ttgaagaaca agagccgtgt
    31081 cttccaccaa cgtctcaaat ctacaattga gagtcagttg gctattgttg aatcttcaga
    31141 ttgggaagat attctccgtc caacagctac ttatcttcaa accagtgatg aagcctttaa
    31201 agaagtggtt agcgaagtac ttggagaacc gattccagtt ccaattgaag aagaaccaat
    31261 tgatatgaca cgtcagttct ctcaagcaga aatggaagaa ttacaagctc gtattgaggt
    31321 agccgataaa gaattgtctg aatttgaagc tcagattaaa caggaagtgg aagctccaac
    31381 tcctgtagtg agtcctcaag ttgaagaaga gcctctgctc atccagttgg cccaatgtat
    31441 gaagaaccag aagtagctcc agtgcatccg acaggtccaa caccagctac agaaactgtt
    31501 gattcagcac cgggatttga agcaccgcaa gaatctgtta caattttata agaaatattc
    31561 tgagaacaat atcttatcct tatattccca gcgagcagga gatggtgtga gtcctgcatt
    31621 ccctatcgat aagattatcc tctcaaaaac tcaagtctga atctagtaag atttgacgtt
    31681 ccccacgtta cgggataaga gggagaaaga ctaaaacttt ttccgaataa aggtggtacc
    31741 acgattttcg tcctttttgg aagttgtggt ttttaatttg ttattattta taaaggagat
    31801 accatgaaac tcaaagacac ccttaatctt gggaaaactg aattcccaat gcgtgcaggc
    31861 cttcctacca aagagccagt ttggcaaaag gaatgggaag atgcaaaact ttatcaacgt
    31921 cgtcaagaat tgaaccaagg aaaacctcat ttcaccttgc atgatggccc tccatacgct
    31981 aacggaaata tccacgttgg acatgctatg aacaagattt caaaagatat tattgttcgt
    32041 tctaagtcta tgtcaggatt ttacgcacca tttattcctg gttgggatac tcatggtctg
    32101 ccaatcgagc aagtattgtc aaaacaaggt gtcaaacgta aagaaatgga cttggttgag
    32161 tacttgaaac tttgccgtga gtacgctctt tctcaagtag ataaacaacg tgaagatttt
    32221 aaacgtttgg gtgtttctgg tgactgggaa aatccatatg tgaccttgac tcctgactat
    32281 gaagcagctc aaattcgtgt atttggtgag atggctaata agggttatat ctaccgtggt
    32341 gccaagccag tttactggtc atggtcatct gagtcagccc ttgctgaagc agagattgaa
    32401 taccatgact tggtttcaac ttccctttac tatgccaaca aggtaaaaga tggcaaagga
    32461 gttctagata cagatactta tatcgttgtc tggacaacga ctccatttac catcacagct
    32521 tctcgtggtt tgacggttgg tgcagatatt gattacgttt tggttcaacc tgctggtgaa
    32581 gctcgtaagt ttgtcgttgc tgctgaatta ttgactagct tgtctgagaa atttggctgg
    32641 gctgatgttc aagttttgga aacttaccgt ggccaagaac tcaaccacat cgtaacagaa
    32701 cacccatggg atacagctgt agaagagttg gtaattcttg gtgaccacgt tacgactgac
    32761 tctggtacag gtattgttca tacagcccct ggttttggtg aggacgatta caatgttggt
    32821 attgctaata atcttgaagt cgcagtgact gttgatgaac gtggtatcat gatgaagaat
    32881 gctggtcctg aatttgaagg tcaattctat gaaaaggtag ttccaactgt gattgaaaaa
    32941 cttggtaacc tccttcttgc ccaagaagaa atctctcact catatccatt tgactggcgt
    33001 actaagaaac caatcatctg gcgtgcagtt ccacaatggt ttgcctcagt ttctaaattc
    33061 cgtcaagaaa tcttggacga aattgaaaaa gtgaaattcc actcagaatg gggtaaagtc
    33121 cgtctttaca atatgatccg tgaccgtggt gactgggtta tctctcgtca acgtgcttgg
    33181 ggtgttccac ttcctatctt ctacgctgaa gatggtacag ctatcatggt agctgaaact
    33241 attgaacacg tagctcaact ttttgaagaa catggttcaa gcatttggtg ggaacgtgat
    33301 gccaaagacc tcttgccaga aggatttact catccaggtt caccaaacgg cgagttcaaa
    33361 aaagaaactg atatcatgga cgtttggttt gactcaggtt catcatggaa tggagtggtg
    33421 gtaaaccgtc ctgaattgac ttacccagcc gacctttacc tagaaggttc tgaccaatac
    33481 cgtggttggt ttaactcatc acttatcaca tctgttgcca accatggcgt agcaccttac
    33541 aaacaaatct tgtcacaagg ttttgccctt gatggtaaag gtgagaagat gtctaaatct
    33601 cttggaaata ccattgctcc aagcgatgtt gaaaaacaat tcggtgctga aatcttgcgt
    33661 ctctgggtaa caagtgttga ctcaagcaat gacgtgcgta tctctatgga tattttgagc
    33721 caagtttctg aaacttaccg taagattcgt aacactcttc gtttcttgat tgccaataca
    33781 tctgacttta acccagctca agatacagtc gcttacgatg agcttcgttc agttgataag
    33841 tacatgacga ttcgctttaa ccagcttgtc aagatcattc gtgatgccta tgcagacttt
    33901 gaattcttga cgatctacaa ggccttggtg aactttatca acgttgactt gtcagccttc
    33961 taccttgatt ttgccaaaga tgttgtttac attgaaggtg ccaaatcact ggaacgccgt
    34021 caaatgcaga ctgtcttcta tgacattctt gtcaaaatca ccaaactctt gacaccaatc
    34081 cttcctcaca ctgcggaaga aatttggtca tatcttgagt ttgaaacaga agacttcgtc
    34141 caattgtcag aattaccaga ggctcaaact tttgctaatc aagaagaaat cttggataca
    34201 tgggcagcct tcatggactt ccgtggacaa gctcaaaaag ccttggaaga agctcgtaat
    34261 gcaaaagtaa tcggtaaatc acttgaagca cacttgacag tttatccaaa cgaagttgtg
    34321 aaaactctac tcgaagcagt aaacagcaat gtggctcaac ttttgatcgt gtcagacttg
    34381 accatcgcag aaggaccagc tccagaagct gcccttagct tcgaagatgt agccttcaca
    34441 gttgaacgcg ctgcaggtga agtatgtgac cgttgccgtc gtattgaccc aacaacagca
    34501 gaacgtagct accaggcagt tatctgtgac cactgtgcaa gtatcgtaga agaaaacttt
    34561 gcagatgcag tcgcagaagg atttgaagag aaataagatt gaaaagtcta ggcaaaattc
    34621 aatttgagaa gaaaagacaa ctaattttat agtctattaa acgcattgta tcacgttttt
    34681 gaacacctga tatgatgcgt tttttatttt taaaatttgc aaggtgtgac tttttatact
    34741 catactcaat gaaaatcaaa aagcaaacta ggaagctagc cgcaggctgc tcaaaacact
    34801 gttttgaggt tgtagataag actgacgaag tcagtaacat atatatggta aggcgacgct
    34861 gacgtggttt gaagagattt tcgaagagta tcaacaagaa tcaaagagaa acttagcaag
    34921 ctaacagtag taagataaaa taggaatttg ata
//
LOCUS       DAVIME010000019        34769 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVIME010000019 DAVIME010000000
VERSION     DAVIME010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.019"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(97..499)
                     /locus_tag="VV588_000983"
                     /pseudo
     CDS             complement(97..499)
                     /locus_tag="VV588_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(575..1015)
                     /locus_tag="VV588_000984"
     CDS             complement(575..1015)
                     /locus_tag="VV588_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU7083344.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLREKLLEQALLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQRRSGSVVQEFLGNYSGYMHCDMLRQ"
     gene            1006..1313
                     /locus_tag="VV588_000985"
                     /pseudo
     CDS             1006..1313
                     /locus_tag="VV588_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1336..1686)
                     /gene="tnpB"
                     /locus_tag="VV588_000986"
     CDS             complement(1336..1686)
                     /gene="tnpB"
                     /locus_tag="VV588_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU7083345.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(1667..1852)
                     /locus_tag="VV588_000987"
     CDS             complement(1667..1852)
                     /locus_tag="VV588_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083346.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2156..3718)
                     /gene="guaA"
                     /locus_tag="VV588_000988"
     CDS             complement(2156..3718)
                     /gene="guaA"
                     /locus_tag="VV588_000988"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU7083347.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3860..4558
                     /locus_tag="VV588_000989"
     CDS             3860..4558
                     /locus_tag="VV588_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU7083348.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4601..5497)
                     /locus_tag="VV588_000990"
     CDS             complement(4601..5497)
                     /locus_tag="VV588_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU7083349.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILHIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5506..6441)
                     /locus_tag="VV588_000991"
     CDS             complement(5506..6441)
                     /locus_tag="VV588_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU7083350.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARFLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6438..7163)
                     /locus_tag="VV588_000992"
     CDS             complement(6438..7163)
                     /locus_tag="VV588_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU7083351.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7247..7882)
                     /locus_tag="VV588_000993"
     CDS             complement(7247..7882)
                     /locus_tag="VV588_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU7083352.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7884..8711)
                     /locus_tag="VV588_000994"
     CDS             complement(7884..8711)
                     /locus_tag="VV588_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU7083353.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8733..9659)
                     /locus_tag="VV588_000995"
                     /pseudo
     CDS             complement(8733..9659)
                     /locus_tag="VV588_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10310..10921
                     /locus_tag="VV588_000996"
     CDS             10310..10921
                     /locus_tag="VV588_000996"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU7083354.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10966..11694
                     /gene="rlmB"
                     /locus_tag="VV588_000997"
     CDS             10966..11694
                     /gene="rlmB"
                     /locus_tag="VV588_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU7083355.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11733..12644)
                     /gene="trxB"
                     /locus_tag="VV588_000998"
     CDS             complement(11733..12644)
                     /gene="trxB"
                     /locus_tag="VV588_000998"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU7083356.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12710..12934)
                     /locus_tag="VV588_000999"
     CDS             complement(12710..12934)
                     /locus_tag="VV588_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU7083357.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAGARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13012..13755)
                     /locus_tag="VV588_001000"
     CDS             complement(13012..13755)
                     /locus_tag="VV588_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU7083358.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13755..14555)
                     /locus_tag="VV588_001001"
     CDS             complement(13755..14555)
                     /locus_tag="VV588_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU7083359.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14713..15069)
                     /locus_tag="VV588_001002"
     CDS             complement(14713..15069)
                     /locus_tag="VV588_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU7083360.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLSVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15082..15594)
                     /locus_tag="VV588_001003"
     CDS             complement(15082..15594)
                     /locus_tag="VV588_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU7083361.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15594..16088)
                     /locus_tag="VV588_001004"
     CDS             complement(15594..16088)
                     /locus_tag="VV588_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083362.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16223..16669
                     /locus_tag="VV588_001005"
     CDS             16223..16669
                     /locus_tag="VV588_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU7083363.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMINNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16666..17313
                     /locus_tag="VV588_001006"
     CDS             16666..17313
                     /locus_tag="VV588_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU7083364.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKNVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17334..17915)
                     /gene="pdxT"
                     /locus_tag="VV588_001007"
     CDS             complement(17334..17915)
                     /gene="pdxT"
                     /locus_tag="VV588_001007"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU7083365.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLLIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17916..18791)
                     /gene="pdxS"
                     /locus_tag="VV588_001008"
     CDS             complement(17916..18791)
                     /gene="pdxS"
                     /locus_tag="VV588_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU7083366.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18943..20322)
                     /locus_tag="VV588_001009"
     CDS             complement(18943..20322)
                     /locus_tag="VV588_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU7083367.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20616..21539
                     /locus_tag="VV588_001010"
     CDS             20616..21539
                     /locus_tag="VV588_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU7083368.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     IFWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21599..22204
                     /locus_tag="VV588_001011"
     CDS             21599..22204
                     /locus_tag="VV588_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU7083369.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22223..23467
                     /locus_tag="VV588_001012"
     CDS             22223..23467
                     /locus_tag="VV588_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU7083370.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23583..23840)
                     /locus_tag="VV588_001013"
     CDS             complement(23583..23840)
                     /locus_tag="VV588_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU7083371.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23882..25918)
                     /locus_tag="VV588_001014"
     CDS             complement(23882..25918)
                     /locus_tag="VV588_001014"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU7083372.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKEIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26130..27047)
                     /gene="glyQ"
                     /locus_tag="VV588_001015"
     CDS             complement(26130..27047)
                     /gene="glyQ"
                     /locus_tag="VV588_001015"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU7083373.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27415..28176)
                     /locus_tag="VV588_001016"
     CDS             complement(27415..28176)
                     /locus_tag="VV588_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU7083374.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFFTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28449..29291)
                     /locus_tag="VV588_001017"
     CDS             complement(28449..29291)
                     /locus_tag="VV588_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU7083375.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYHAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29405..30796)
                     /locus_tag="VV588_001018"
     CDS             complement(29405..30796)
                     /locus_tag="VV588_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU7083376.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKSFSDQDLSAWNFDYKDS
                     QIILYSSPVLENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31031..31408)
                     /locus_tag="VV588_001019"
     CDS             complement(31031..31408)
                     /locus_tag="VV588_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU7083377.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMSYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            31641..32618
                     /locus_tag="VV588_001020"
     CDS             31641..32618
                     /locus_tag="VV588_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU7083378.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYSKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGTLFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQDPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32615..33697
                     /locus_tag="VV588_001021"
     CDS             32615..33697
                     /locus_tag="VV588_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU7083379.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTLIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGSEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33761..34769)
                     /locus_tag="VV588_001022"
                     /pseudo
     CDS             complement(33761..34769)
                     /locus_tag="VV588_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10298 a         7777 c         6279 g        10415 t
ORIGIN      
        1 agctcttgct ttagctcctt caaaactttg agaaaaaacc accctcgctt ttttaaactg
       61 agcttaggct aaaagagtcc agtggactct tttactccgt cccataacca atgatttaat
      121 ggcgcgttca gctagattat tggaaaggac cagatgtccg tcttttaaaa tggtcttaaa
      181 ggtttcttca tacttgaggc tgtattcaat tgcccttcct ggttttgaac ctgctaaaac
      241 tgactgacgg cggcaccaag caaagaagtc ttccattaag ggctggacgt ttctgtagtc
      301 gttcatcagc tggcaaagcc tcccagtctc tttccaaggc aaataactgg tcacgatagg
      361 ctaaaccttt agctcctaag gatgatttat ctgcttgctt gggggtcgct tcaaaaaatt
      421 tccttctcac atgcgcccaa catccaacaa gttcagcttc ttccagttga cgataagctt
      481 ctagcggttc gcagtttacc aagcttagcg tcgccttgct cctaaacctt agactgctat
      541 cgcataggca gaactagagg actaaagttc taagttactg ccgcaacata tcacaatgca
      601 tatagccaga ataatttcct aggaattctt gcactaccga accactccga cgctgatcat
      661 ggtggtacag cgtaatccct tgtttctcag ctttcccaga caaaaaagtc caatagtaag
      721 tcagctgact atcactttct aagacccgat aagaggtttc atctgcatga agaagagctt
      781 gttctaacaa cttttctcgt aaaaggttat aaaggggctc caaatagtat tgactcgtct
      841 tgatatgcca attagagatt tccttacgtg tgattggtaa acccatccta gcccaatctt
      901 cttcttggcg ataattgggt accttcagat taaacttctg atggatggtg tgagcgataa
      961 tagaagctga gccaaggcta tgcgccaaag gggctttagg aataggagct ttcacaagct
     1021 tatccagatg attatctttt actcgttatg gacaatgcta tatggcataa atcaagtacc
     1081 ttaaagattc cgactaatat tggctttgca tttattcctc catacacacc agagatgaac
     1141 ccattgaaca agtgtggaaa gagattcgta aacgtggatt taagaataaa gcctttcaaa
     1201 ctttggaaga tgtcatgaat caacttcaag atgttataca aggactggag aaggaggtga
     1261 taaagtccat cgttaatcgg agatggacta gaatgctttt tgaaagcaga tgagtataaa
     1321 aagaaagtcc tcatttcaat agaaatcacg actttctgat aaatttattt tgggagtgat
     1381 agaaaagccc ttcataagcc aatctacttg ttcaggtgtg agagctttga catccttttc
     1441 tgtactgggc caagtcagtc tgccgttctc aaagcgttta tatagtagcc aaaatccttg
     1501 accatcccag taaagggctt taaagcggtc tttacgtcca ccacaaaaga gaaaaacttg
     1561 accggagaaa ggatccaatt caaagtgggt tttaaccaga taagccagtg aatcgattcc
     1621 ttgtctcata tcagtcttcc cacacacgag atagacctgc cctaggctag atagatgaat
     1681 tgtcatagag caacacctta tccaaaagct gttctaccat ttcgagattg agagattgaa
     1741 aaaaacttac ttcaagcttg ccaatacgaa ttttaagcag aatatcattt ctctttttag
     1801 aatcaaaagg acgagattgt ggaatctcta caggaacaat aggttgtggc attaaaatat
     1861 cctccaatag ttttacttta ctaatagtat acaggaggaa ctccatgaat gatagatacc
     1921 ttgttatgac gcgcttacta tattagaaag ttggctctct aattaaatta attctcatta
     1981 tatatatcaa aagaccgcag tttgaaaact acggtctaat tttttgtcca aatgtaaatc
     2041 acttggaact attattcaat ttattctttt tagtaaatgt tcccgtttta atcccagtta
     2101 cagtttttaa tcctctgtaa ccgttgattt tacaaagctt ttaatttttt tgcgattact
     2161 cccactcaac tgttgcaggt ggtttacttg taatatcgta gacgatacgg ttaacatgat
     2221 ccacttcatt tacgatacgt actgagattt tttgaagtac ttcccatgga attttggcaa
     2281 aatcagcagt cataccatcg atagaagtga tagcacggat tgcaatcgtg tagtcatacg
     2341 tacgaccgtc acccataaca ccgactgaac gaacgcctgt gttaacagtg aagtattgcc
     2401 aaatatcgcg gtcaagtcca gctttagcga tttcttcacg aagaatagcg tctgattcac
     2461 gaacggtttc aagtttctct tcagtgattt cacccatgac acggatagca agtcctggtc
     2521 ctgggaatgg ttggcgccat acgatatggt ctggcatacc aagctctgta ccaagagcac
     2581 gaacttcatc cttgtaaaga gtattgagtg gttcaatcaa ttcaaactgc atatcttctg
     2641 gaagaccacc cacgttgtgg tgtgacttga tagtttgagc tgtatccgta ccagactcga
     2701 taacatctgt atataaagta ccttgagcaa ggaatttcac atctttgagc ttgcttgctt
     2761 cgtcatcgaa tacatagaca aactcgttac caatgatttt acgtttttgt tcaggatcag
     2821 aaacgccagc aagtttgtca aggaaacgtt tagcagcgtc tgctttgacg atattcaaac
     2881 caaacttacc accgagcatg tccataactt gatcagcttc gcctttacga agaagaccgt
     2941 ggtctacgaa gatacagatc aattgatcgc caatcgcttt ttggagaaga accccaacga
     3001 cagatgagtc aacaccacct gatagaccaa gaaggacacg tttatcaccg acggtttcac
     3061 gaattttttt gatctgcatg tcaatgaaat tatccattga ccagtcacct ttagccttac
     3121 aaatgttaag ggcaaagtta cgaaggatat catttccgta tacagaatga cgaacttctg
     3181 ggtggaattg gataccgtaa atgtgtttat ctgggttttc gatggctgcg tatgggcagt
     3241 cagctgatgt acctgtacga acaaagtcag caggaatctc agtaaccgca tcaccatggc
     3301 tcatcaaaac agtctgttca tcaggtgttg attcaaaaag cgctgatggt gtgtgagtta
     3361 gggttgattg accgtattca cgatttccag catcacctgc aggaacaact tttcctccaa
     3421 gtttatgggt caataactgc ataccataac agattcccaa aattggaatt ccgagttcga
     3481 agatttctgg gtcaatatca aatgaaccat cttcatatac agaatttgga ccacctgata
     3541 gaataattcc tacaggattg acttcacgaa cttcagcagc tgaaatttta tggcttttta
     3601 gttctgaaaa aacaccaatc tcacggatac ggcgtgaaat cagctggttg tactggctac
     3661 catagtccaa tacgatgatt ttttctacat cttgcaaatc agttgaaatg ttgctcatct
     3721 ttttcctttc tcaaaagaaa tatcttttct caatattcta tcacaaataa gggcgaatta
     3781 ccaactaaac aaggcgaagt ttgacttttt ctagtttatt ggggtacaat agagaaaaga
     3841 tagaaatgaa gtgaaaaata tgctacctgc ttatatgaaa atccatgatc agataaaaaa
     3901 ggatattgac gagcaccgtt gggctattgg tgagaggctt cccagtgaaa gagatttagc
     3961 tgagcagttt gcggtcagtc gcatgaccct ccgccaagcc gtatctctat tagtcgaaga
     4021 aggcgtctta gagcgccgtg taggaagcgg cacctttgtt tccagtactc gagtacaaga
     4081 aaagatgcga gggacaacca gttttactga aattgtcaaa tcccaaggta aagttccctc
     4141 tagccagctc atttcctaca aaaaaaccat tcccaatgag caagaagttg ccaagctagg
     4201 aatttttcca acggacaata ttatccgaat ggagcgggtc cgctatgccg accaagttcc
     4261 cctagtttat gaagttgctt ctattcctga aaaattcatt aaggacttta aaaaagaaga
     4321 aatcaccagt catttcttcc aaaccttgca aaaacatggc tatcgtatcg gtaaatccca
     4381 acagaccatc tatgctcgcc ttgctaaaga aaagattgcc cactatttgg aagttgaaaa
     4441 aggacatgct attcttggat tgacccagat ttcctaccta gaagatggta ctgcttttga
     4501 atacgtaaaa agtcaatatg taggcgaacg ctttgaattt tatcttgaaa ataattagat
     4561 taccacgcaa aaactctctg tcacggacaa agagtctttt ttatttttct aagaataaat
     4621 ctttcaaaga aatcaaagtt acagcaaaca atatcattgc cataccaaga aaatcaatgg
     4681 gataaaattg ttcattcatt attaagaagg caaagaaaat cgccgatatt ggctcaattg
     4741 aagccaacaa gcttgacttg accggtccta tcagactggc tcctttaagg aaagctgtat
     4801 aggcaaagac agtcccgata aggataatgc ctgcaaacgc aaggagaaaa tcaagactag
     4861 tcgggatatc ggcctgtaga acccctgtaa aaggaagggc gaccaaacct gctatgacca
     4921 ttcccacacc aatgaccaag ctgctccccc actttttaat caaggctatg tgtaaaatga
     4981 tatacaaagc ataagtcaag gcagaaaaga gaccccagaa cagaccagca ggtgtcatgg
     5041 ataactggtc caactgccca tgtgttgcga tcaggaaggt tcctccgatg gcgaatatga
     5101 tggaaactat ctctcccagt gtcggtgcca ccctatcctt gatacagcta taaattaaaa
     5161 ttccgacagg acaaacatac tgaagcaccg tcgctgttcc cgcattggtc tcctgaatag
     5221 cagacagata ggcgaattgg ttgagaaaaa gaccaatcag agcaaaaata agaagagaca
     5281 gcaaactctt tctatccttt aaaaagacca gtattttatc ctttgcagta gcataagcca
     5341 agagcatgag aattccacca gcgattaaaa gacgcaagtt agtcaagacc agagccgaaa
     5401 ttccgtgtgc cattaggtat tggccactcg ttcctgacaa cccccaagca ataccagcca
     5461 caactgttag taaagtccct tttaaactat ttgacatgtc tctccttact cttctttgcg
     5521 aatcaagttc atcacttgat tgcggtctaa tatccattga gctctctcgt ccttttcata
     5581 ggtacgattc gataggaaaa tagtggcttc ttgcttctga cgattccaca tgataaaggt
     5641 acctgtatag cccgtatggt ctagccaatc tccttccaaa ttccatgcta aagaacgttc
     5701 cttgtcatcc aaaggagaaa aattttgatt taagtctctt gcaaaatcat ctgctaaata
     5761 gtgttctaaa aagatttgta aatcctttat agtcgaaaat aaaccagcac tcccagcatg
     5821 tctacccagg aaacgagcct tgggatcatg cactatgcct gcctctacac ctctaactgt
     5881 tggaacagca agctcaactg gcccaaactt agtttccgtc attccccaag gtttccagac
     5941 ttgatccttt aaaatcacat ccaaatcttg attaaaaatt ctttccaaaa taaagcccaa
     6001 cagcaaaaaa tggacatccg aataaagaaa ggctggctga cttcgtctgt tgagatgaaa
     6061 catcgcttcc tttaattcag gggctgttaa aagatcacga ttaggaataa aaggatcaag
     6121 gtctgttgca tgagtcaaga gctggcgaat agtgatgtct ggataatcac tctcaggtaa
     6181 aaaatctatt accagtctat caatatctaa ttgacctatt tcccacaaga aggtacaaac
     6241 tgtgccaacc ccaacaacct tgctgacact agctaggtca taaactagtc ctgcctcagt
     6301 ctgcaagcca tgctctgggg cactctggcc taaatagaac tctgtccatt gattgtcctt
     6361 aaaatacgca aaagaggctc cgggataaat tcctgcctcg atttgttctt ctattttttt
     6421 aataatcttg gtccacttca tacttcttca aaccacaatt caacattatt tctatcttta
     6481 ccaaggaaga atttttcaga cttaggaata aaatattcag tagactcaaa cttctggcga
     6541 agacttgcta tgtctaattc attgaccaag aacttgagca tagataagtc ccaggtaacc
     6601 gtattgtcca cagtcaaatc ctgcccctga gctggaataa aatcaaggga tgccccaatt
     6661 tcagatgatt ccaagaaact ttcgatatca gttgggagat gtaattccat agaaatctca
     6721 aatttactta aagaaattga tgccaaatct gtttgaaatt caggcttttc tcctacttct
     6781 actagacttg ctctgtcatc ttccgcatga atcaaaatca aatcatcttc tggtgagaaa
     6841 atttcaaaag cgtagccatt ttgaccttta tataatcgat gaatcgaatc tgttttagat
     6901 aagattcctt caatttctaa gggattttcc accttgacaa tcaatctagc tagttttttt
     6961 cttccctcta ccttacgagt acgcatactg ggagcttctt ctaaaaccag cttttcaaga
     7021 cccgtttggt cacctagtga cagaaaggcc gattcttcta acagggcctt cattccaagg
     7081 gtttcaatat aaaatgtttc atttaatttt ctattattag cttttaaagt aggaataatc
     7141 cgtacaatct gatttacatt cataaattcc tccgtcactt tttattttaa aggattttag
     7201 aattttttac aagatattat gctcaaattt aacattattt agctatttag taaagatagt
     7261 ctttcaaggc ttttgacaaa gcctgataac cagcaatact gaggtgcagt ccatcagttg
     7321 tatattcttt tttgagttgg cctgcttggt ctgtcaaaca atcaaatact ggcacaaatt
     7381 ccacctgcat ataggcagat gcaagctctt gataggcttg attccaattc tgaatttttt
     7441 cattcgagcg gatatagact gcctgctggt acttctctcc ctcattgaca ggcaaaatgg
     7501 aaagcaattt aatctctgtc aatggataat cgcgagcaac ggattgaatg atagcttcga
     7561 gattattgag agcctcattc acaggaacat cctttccgat atcatttgtc ccaatcagaa
     7621 gaaaaatttt atctactgct ccaccatata gatgagcatc aaggttctct agtaacagtc
     7681 ctgtctgata gccacgaatt cctcgattga caatcgtctt tgaagtccca aatagctcct
     7741 gtagaggata atactcgaca atggaatccc caataaaaag aatgtttggt tctacaacag
     7801 aaatgtgatt taggtgacga tatttggttt gaattttttc ttgttccttt aggagccaat
     7861 tttctaataa ctgtactgcc acttcattct cctttttcta accagttttc caagacttga
     7921 taaactcctc cttggctgtt ggctggtgct agagcagtcg ccacagcttt ggctttctca
     7981 tcagcatttt ccatcgcata ggcaattcca gccatttcaa gcatttcaac atcattttca
     8041 ctatcaccaa aagccatgat ttcttgggat ttcaagtccc agcgcttgag taattcctcc
     8101 aagccccatg ctttatgaat cccagcttgg aggatatcaa tgcaaccata gccactggat
     8161 acagctcgga cacggccatc aaagagagca ttgatttctt ccaaaaccga actcaaacgt
     8221 tcctcaccaa caaccatgct catcttgagc acaccaccaa agaggtcaga tgttaattca
     8281 tccacaaatt gcatccgttg gtagaatttt tcaatcattt ctggagtcat aaaactttca
     8341 agatctgtaa aaatcgtacc ttccttgaca aaatcaccct tcatccccgt tacaacaaac
     8401 tggtcctgac acgctcgacc cttgaaatga gccaaagcct tgttgacaat ggcgtcatcc
     8461 catgtctgag cctgaatcaa ttcattgttt tcaaaaatac gagcgccatt agcaacaacc
     8521 agaaccactc gatccaccaa gggactcagt agttgtctca tgcggtgaat ttcattgccc
     8581 gtcgcaatga caaaacgaat gcccctttga tccaactgat ctaaaatctt ttccaatcgt
     8641 gggagatcaa gctgacctct agcatccagc aaggtcccat ccatatctgt cgcaattacc
     8701 ttaatcatca tttactttcc tctggattca agctaatacc acttcaatcc cacatgttca
     8761 ttcatttctt tataggctgt atcaattcgt tccttagtcg cttcatctaa ctggtcacga
     8821 tgactgccat cctctataaa atcttccaaa atataagttt ggtaatgata caagggatat
     8881 ccttctggtg aaaaggttcc ctttggtgtt cgattgaccc aagtaggatg agctttagct
     8941 gttccgatag ttgtttttcc atccttcttc ttgatggtga catccatgag aacaccacgt
     9001 tcagtccact tagcattctc ttcatctccc atagattcaa tccgttgatt ggaaatgaag
     9061 ttccccattt aatagataat gagtttctta tctccatctt tttcaaccgt ttcagatggt
     9121 tcaacaacgt gaggatgccc tccaaagata atatccgctc cccaatcgat catcttgtga
     9181 taaagagctt tttgttcttc agttagttcc aatcgatact caacacccat ctgaagcatg
     9241 ataatggtga tatctgcttc cttctctgcc cgttcaattt caaccttcat cttatcttcg
     9301 tttaaatctg aaagataacg attatagtct tcctgagaaa tatactgctc aattccattg
     9361 aaaccatagg aataggctaa caatgcaacc ttgataccat tcacttcctt aatgaccagc
     9421 ggagcctgat cacgtggttc gtgcgtataa actccgattg gagtgattcc agctttctca
     9481 ataatatcgg ccgttgaaat aactccctca atttgcgaat ccaaaatatg attatgagct
     9541 aaatccagca catgataacc tgcctcctta atagcatcca taacttcagc aggagcatta
     9601 aagagaagat aacccgctaa ataatgatcc ttattaatgg ttccttcaaa atcaccaata
     9661 gctaaatctg ctgcttagtc cccttgcttg agccaaggag tcacatactc aaaattttca
     9721 tgaaagtcat aggtaccgtc ttctttttta gctgaaaaga aaagtccatc gtggtagagc
     9781 aaatccccgt gggccataat tctggcagtt ttttcctctt cctactcctg agacttttgc
     9841 ttagtcccct cttgagaaat agtatctcgt ttttgactag tcaagggatt ccttggaagc
     9901 tttcaaacaa caagaccaag cccattgata aatcaactgc tagcaagagt atcgccacaa
     9961 atcccttatt gctccacttg cgataactcc taaaaagttt accaagccct tcataaaacg
    10021 aaaagctaaa ccaccctgat ttcgattttg tcttctttgt atcttcattc tccctacttt
    10081 cttatgcaag ccttttcttt ttattatatc acagataagt atttctttca caattgaatt
    10141 gaacttccca tctattttct ataaatccta aatgccataa tgctttcaat tcttgtcatt
    10201 ttgtgatatc atgtagagga aatgaactaa tccacagtgg cttattccaa gtataccact
    10261 tgggctttgg cagtagctaa ctgcactaaa cataatataa ggagagaaaa tgtctgcaat
    10321 agaacgtatt acaaaagctg ctcacttaat tgatatgaac gatattatcc gtgaagggaa
    10381 tcctactcta cgcgcgattg ctgaggaagt cactttcccc ctatctgacc aggaaatcat
    10441 cctaggcgaa aagatgatgc aattccttaa acattcccaa gatcctgtca tggctgaaaa
    10501 aatgggactc cgcggtggtg ttggactggc tgctccccag ttagatatct caaaacgcat
    10561 tatcgctgtt ttggtaccta atattgttga agaaggcgaa actccacagg aagcctacga
    10621 tttggaagcc attatgtaca atccaaaaat cgtctctcac tctgttcaag atgctgctct
    10681 tggcgaagga gaaggttgcc tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca
    10741 tgcccgcgtt actgttgact actttgacaa agatggagaa aaacaccgta tcaaactcaa
    10801 aggctacaac tccattgttg ttcagcatga aattgaccac attaacggta tcatgtttta
    10861 cgatcgcatc aatgaaaaag acccatttgc agttaaagat ggtttactga ttcttgaata
    10921 aagaaaatcc cgttgcaaga cggggttttg tgttataata gaggcatgaa aacaaatgat
    10981 attgtctatg gcgtccacgc cgttaccgaa gccctccttg caaatacagg aaacaaactc
    11041 tacctccaag aagatctccg aggtaagaat gttgagaaag tcaaggaact agctacagaa
    11101 aagaaggtgt ccatttcttg gacatcaaaa aaatctctct ctgagatgac tgaaggtgct
    11161 gttcatcaag gttttgttct acgagtgtct gaatttgcct atagcgagct agattacatc
    11221 cttgcaaaaa cacgccaaga agaaaatcca cttctattga ttctagatgg tctaaccgat
    11281 ccccataatc tgggttctat cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc
    11341 attcccaagc accgtgctgt cggagtaact cctgtcgttg ccaaaacagc cacaggtgct
    11401 attgaacacg ttccaattgc ccgagtgacc aacctcagtc aaaccttaga taaactcaag
    11461 gatgaaggct tctggacctt tggaacggat atgaacggta ctccttgcca caagtggaat
    11521 acaaaaggga aaatcgccct catcatcgga aatgaaggaa aaggcatctc tagcaacatc
    11581 aaaaaacagg tcgatgaaat gattaccatt ccgatgaatg gacatgttca aagcctcaat
    11641 gccagtgttg ctgcagccat tctcatgtac gaagtttttc taaatagact ataaaaaagt
    11701 ttccagtcat ctgattggaa acttttttat gattaactat gttctgtgat aaacttgtag
    11761 gcttcttgac cagcgatagc tccatctcca actgctgttg ttacttggcg aaggtctttc
    11821 aagcgaacat ctccaactgc aaagataccg tcgactgcag tcttcatgtg gctatctgtc
    11881 acaatccagc ctgcctgatc ttggatattc aattctttaa caaaatcgct aagagggtcc
    11941 aaaccaacat agataaagac accaccgaag gcttgctctg tcacttgacc tgttttcaca
    12001 ttttcaaaaa cgacagattc tactctgttt tcacccttga tttccttcac tacagaatcc
    12061 cagataaagc tgattttttc attcgcaaag gcgcgatctt gtaaaacctt ttgggcacga
    12121 agttggtcac gacggtgaac aatggtaaca gtcttagcaa aacgagtcaa gaagagggct
    12181 tcttcaacag ctgaatctcc accaccaact accaataaat cttggtcacg gaagaaagca
    12241 ccatcacaca cagcacagta agaaacacca cgactgttca gttcttcttc tccaggcact
    12301 cccaaaggac ggtgtttaga accagttgct acgataactg tacgtgtttc atatgtttgg
    12361 tcatcagtca tcactttctt aaaatcacca tggtcttcga cattttcaac ataaccataa
    12421 atgtgctcaa caccaagatt ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca
    12481 ctaatattag catatcctgg gtaattttcg atatcagatg tattattcat ctgaccacct
    12541 ggcagaccac cttcaatcaa agctactttt agattgcttc gagcagcata caaggccgca
    12601 gtcatccctg caggtccagc accgataata atagtatcgt acatatagat tccttctttc
    12661 ttgttgtaac tatctttatt ctaactcttt cttgtcaatc acgcaaggat tatgccttga
    12721 aaacaagaat taaactcata accgcaaagg ataatactgg gacaaccaag actccaatca
    12781 taatcatatc atagagatgg gcttggcgag ccccggctgt cttatcaact cccgacatgg
    12841 ctctcagacc aatccaaatc cctaaaaaaa tcagaacaag gatggtggtc aagatcaaac
    12901 tctcgaaata taaagaaaat agttgcagta gcatgatttc tctcatttct atctttttta
    12961 aagagtaaac tcagctagtc caactaactg agttttcctt tatctattat atcaaatata
    13021 agtccgtttg taactagcaa agaattcttt tgtccgctct tctttagggg tgtggataat
    13081 ctcatccgga gttccagact cgatgatttt ccccttatct aagaagagaa ttttatccgc
    13141 aacttgggct acaaaggaca tgtcatgact gaccaaaatc atggtctgac ctgacttagc
    13201 agcatctgca atagactttt ctacttcacc gaccaattct gggtcaaggg ctgaagttgg
    13261 ttcgtctaag agcaaaacat ctggtttcat agcaagcgca cgcgctaggg caacccgttg
    13321 cttctgtcca cctgataaat ggcgaggata atggttttca cggtccgaaa gcccaacctt
    13381 agccaactct tccttggcaa tcttagtcgc ttcttggtca gataatttct tgacaacaac
    13441 caagccttct ttcacattat caagtgctgt tcggcgttca aataaattaa actgttggaa
    13501 aaccatagac aacttacggc gtagggcaag gatttcttct tgagtgattt tagaaaaatc
    13561 aactgaaaaa ccatcaatct gaatagagcc actgtcaggt gtttcaagat aattgagact
    13621 gcgaagaaag gttgattttc cagctcctga agaaccaatc aaggctacaa cttccccttt
    13681 ttgaatatcc aagttcagat gatccaagac agtctgtcct gaaaaggatt tgcttaaatt
    13741 cgaaatctta atcattaacg aaggtctcct ttcacatctg tttgcactgt atcaggtgca
    13801 gaaatagcca tttttctctc gatgaaacga ccgaggcttt caattccgat attgactacc
    13861 caataaacaa gggcaacgga gatgaagcgt tcaaaatagc gataatcagc tccacctaga
    13921 atctgagctt gggcaaagac ttccacaaca cccgcactaa aagctagaga tgttcccttg
    13981 gtcaaaccga tgagggaatt aatcaaggtt ggagtagcta ccaccgctgc attaggaata
    14041 atcactcgtc gataaacttg cgctcgggtc atacccagac tgcgcgccgc ctcaatctca
    14101 ccaggattaa ctgagagaat ggctgcacga atggtttcac tagcataagc tgcctcatta
    14161 aaggcaaaag cgacaatcgc aaaagctgca gctggaatcg cattgatatt gagaccagtt
    14221 ccccattgct gattgagggc tttcaaagcc aaagggattc cgtagtaggt caacatgagt
    14281 tgcaccaaaa tcggtgtccc ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa
    14341 atcttgacac gattgatctt cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg
    14401 gcaccaccaa ttgtcaacat aattgttgtt ggaagttgtt ggacaattct agggattcca
    14461 tcaaagaccg aacgtaggct aaacagcttg ccatccggaa tcaattgcat caagttttgg
    14521 taccaatctg atgctaaaat cgttgtaaca ttcataaaaa catcctcttc tgataatgat
    14581 tcattctacc atgcttctgc cgtcaatgaa attatttgct acggtcagat acagactttg
    14641 tctacctact agtttatcat actttgaaac agggaagtta tatattttat ctatcaaaga
    14701 gatagataaa aactatttca gtcccagttc ttcataagat tttcgataac cgatttgctt
    14761 aacagttcca ttttctacta aaatgggccg ttttaacaac ataccgtcac ttgctagcaa
    14821 ctcagccgct tcttggtttg acaaacttcc taccttatct tttagcccta attcacggta
    14881 tttgatacca ctggtgttga aaaattgctt caattcaaat cctgaggttt ctagccaatt
    14941 caaaatgact tcttggctag gtgtttcttc cacgatatgg acggctttat aatccacact
    15001 taattgattt aattcttgtt ttgctttttt acaagttgaa catttggggt attcgataaa
    15061 ttctaacatg tgcttctcct tctatttgtt tatatcttta aaatctacgc cttcatgctc
    15121 caagagccaa gctttctttt ccactcctgc agcatagcct gtcagacgct tgcctgctcc
    15181 caacacacga tgacaaggta ctaggataga ccaaggattg cgtcccactg ctccaccaat
    15241 tgcttgagca gaagccactt gcaggtcttg agcaatttgt ccataggtca ctgtctgacc
    15301 ataaggaatg ccctgtaaat agtcccaaac tctcttttca aaattcgttc cgattggcgc
    15361 caagagcaag ttggataaat cctgaggctt gcctttaaag taatcatcta agcaagcaat
    15421 aactgggtct aaaataggat gactaacaac ttcttctatc gtttcatctc ctagtcccct
    15481 ctcaaaatgc ttctgctcct gaacccaaat tccatacaaa taatggtcat cagctacaag
    15541 tgatagaata ccaattggtg aggagtagag tatttttaca tacttctttt gcattatttc
    15601 tttaattttt gataggccaa gcgttcgcca tctactggca ccttaccaac ttgtttaaaa
    15661 ccaagttttt caaaaatatg ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa
    15721 tcaagataat caaaaccttc aatcaagccc tctaagaagg tttgagcaac tccttttccc
    15781 tgcacatctg ctgccacagc aatacggtga aagactagat actctgactc tccagcttgc
    15841 cagtttccct cataaatagc ttcataggcc tcctctggac tcttggtcac agcagcatag
    15901 gctagcagtt ctccctcttc caaggctacg taggcttgcc ctgagatgat atcatcgata
    15961 ataacatctg catttggata gccattttgc cactggtcac taccagcatc tgctaaacat
    16021 tttttggcat cctccatcac ctgcatgatg gcatctactt catttggaaa agctaaacga
    16081 atttccatct tttttcctca tttctgacta gtttctccca tcatagcata atttaagtat
    16141 ttctacaagc agttaaaact tgactttgtg tttttgttat tttataatct agttatcaaa
    16201 actatataaa aaggagttga aaatgaaaac taccttttcc tacccaaaat gggcagaaat
    16261 tccaaacatt gacctctatc tggaccaggt tttgctctat gtcaatcagg tctgcgcccc
    16321 tatctctcct aataaagaca agggcctaac agcatctatg atcaacaatt atgtgaaaaa
    16381 tggttacctg acaaagcctg acaaaaaaaa ataccaacgc caacagattg cccgtttgat
    16441 tgctatcaca accctcaagt ctgtattttc tattcaagaa atagcccaga cacttaatac
    16501 tctacaaact caagcaagtt cagaccaact ctacgatgct tttgtggact acatgaacca
    16561 aggaattgac ccagctaacc ctattatcca aaccagctgc caaaccgtta aactctatca
    16621 tcaaactcta gacttaatcg atcatactca agaggaggta atccaatgaa cactagtctt
    16681 aaactcagca aacaactcag ttttggagag gagattgcta atagcgtgac ccatgctgtg
    16741 ggtgcagtca tcatgcttat cttgctgcct atttcatcca tctatagtta tgaagcacac
    16801 ggatttttat cctctatcgg cgtttccatt ttcgtcatca gtctctttct catgttccta
    16861 tcatccacca tttatcactc tatggcctat ggttcgaccc acaaatatgt tttgcgaatc
    16921 attgaccatt ctatgattta cgttgccatt gccggctcat acacgcccgt tgtcttgacc
    16981 ttgatgaata actggtttgg ctatctgatt attgtcatcc aatggggaac gaccatcttt
    17041 ggtattctct ataaaatctt tgctaaaaat gtcaatgaga aatttagcct tgctctttac
    17101 ctgattatgg gctggttggt tctggctatc attcctgcca ttatcagtca aacgacaccc
    17161 gttttctgga gtctcatggt aactggcgga ctctgttata cagttggagc tggattttat
    17221 gccaagaaaa aaccttattt ccacatgatt tggcatctct ttatcctagc tgcgtccgta
    17281 cttcaataca tcgctattgt ttattacatg taaaaaagtt gagaaattca atctcaactt
    17341 ttttctttac acatattgat aaagtactgg tgcaagcgca catcatcagt caattctgga
    17401 tgaaaagaac ttaccaacat atttttttct tgggctgcaa caatttgatt gttcactgtt
    17461 gctagaattt ctacaccctc accaacacta ctgataatcg gaccacggat aaaggtcatt
    17521 ggaatcttgc caactccctt acattctgct tccgtgtaga aacttcctaa ttggcgccca
    17581 taagcattac gctcgaccac catatccata gttcctagat aactctcttt ctgagaagtg
    17641 atttccttag ccagcaaaat taagcccgca caggtcccaa acactggtaa gccagataga
    17701 atggcttctc ggatgagaag tagcatgttc tggtcacgta agagcttgcc catggttgta
    17761 gactcaccac caggcaaaat caaacccgac aagtcactct gatcttgctg aaaatcatct
    17821 agatttctga gttctacact ctcgacacct aattgatcta gcacttttgc atgttctgca
    17881 aaggcccctt gcaaggccaa tattccgatt ttcatctatt ttcctcgttc agccatgaga
    17941 atttggattt cattttcatt aataccaacc atggcttctc ctaaatcttc agagatttga
    18001 gctaggattt gaggattacg gaagttagtc acagccttaa caatggcact cgctcgttta
    18061 acaggatctc ctgacttgaa aatacctgaa ccgacaaaga ccccctctgc ccctagttgc
    18121 atcattaacg cagcatctgc tggcgttgca acacctccag cagcgaaatt tacaactggc
    18181 aattttccat gttcatgaac atattggacc aattctacag ggacttgcaa atccttggca
    18241 gcaacataaa gctcgtcctc acgtaagttt tgaatgcggc gaatttcctg attcatcata
    18301 cgcatatgac gaacagcttg gacgatatcc cctgtccctg gttctccttt ggtacgaatc
    18361 atggaagcac cttcagcgat acgacgcaag gcttcaccca aatccttagc accacagaca
    18421 aaaggaactt ggaattcttt cttgtccaca tggaaacggt catcagctgg agatagaact
    18481 tcactctcgt cgatataatc aatttcaata gcctctaaaa tctgagcttc aacaaaatgc
    18541 ccgattctga ccttagccat tactggaata ctaaccgctt cttggatttc cttaatcatc
    18601 tttgggtcgc tcatgcggga aactcctcca gctgcacgaa tatcagccgg aattcgttcc
    18661 aaggccatca cagctgccgc accagcagct tctgcgatac gagcctgttc aggattctgc
    18721 acatccataa taacaccacc cttgagcatc tgtgccaagt ttttatttag ttcataacga
    18781 ttttcagtca tttgttttat cctcatcatt tgtattggta gctacctttt cattttaagt
    18841 cagaacagaa tgaagcacaa gataaaaaaa ctataattgt atggggacaa attagctaaa
    18901 aactatctga ccttaactta aggccagata gctcattcat ttttattttt cagccgtaag
    18961 ggcagccatt gtgatgtagt tgtatggttt gttgaagtgt ggcaagaaga agaggtctgt
    19021 caatgccaat ttatcaattg tcacatgctc ttggatagca agtgagaaca tgtggattcc
    19081 catgctaatt gcaatatcat gtgaaaccat ttgggcacca agaatttcac ggctatcttt
    19141 gtcaaagaca atcttaattg ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg
    19201 aagatcgtta aagcctgttt cagttgcgtt gtaaccagca gctttcgctt tttcaagagt
    19261 caaaccagtt gaaaccatgt gaagaccgta gattgagata ccatttgaac cttgaacacc
    19321 gattccttcc aattcatgtc cacaagcatt gtaggcacca acgataccag tgcgaacagc
    19381 atttgaagca agagcgatat agcttgtatc tttacgagca ttgtcataaa cagtcgcaca
    19441 gtcaccaaca gcgtaaacgc ctgggataga tgtttcttgt ttcttgtcta caaggaaggc
    19501 accgttgcgg aagagttcga tcttaccatc tgcaagggct gtgtttggac ggaaaccaac
    19561 tgcaaggata accatatcca cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt
    19621 accgtcacct tcgattgctt taacagtttg acctagagcc aagcggatgt tgtgatcttc
    19681 caagttcttc gccatcattt gtgtgaagtc tttgtcatag taaccgttca agacagtatc
    19741 aacgatatca acaaggacaa cttcttttcc aagacgttca aaggcttcag caagttcaac
    19801 accgatgtaa ccaccaccaa caacggcgat acggtcgagg tgttggctct tgtcagaaag
    19861 tttattgata acttcttcag cattttggta caatttcacg aattgtacgt tttcaagagt
    19921 tgctttaaat tcgcggtttc ctttaacaat ttcaacacct tcgattggtg gcaagattgg
    19981 tgtagaacct gtagcgaaaa tcaatttttc gtatgattct ttgtgctctt ttccttcaac
    20041 ttccgctgta actactttgt tatcatagtc gattgaaaga acaggtgagt tcatgtaaac
    20101 tttagcacct ttagcttcca atttttcttt atcagaatag aacaagcctt cagcaccgtc
    20161 aatttgttca ccaatccaaa gagccattcc acatcctagg aaagagatgt tagagttttg
    20221 gtcaaataca acaatttcgt tctcatttcc aaaattatcc aacatggtat tgatacatgc
    20281 tgtaccagcg tggttagcac cgactacaac gattttactc ataaaaattt cctgccttca
    20341 ttctaaattt accttactag tataccattt accgttagcg tttacaaggg gggtactatt
    20401 atttcagcat tttttatcaa aaataattcc ccatttatcc tgttttcaag cctcatgaat
    20461 tttatgagca tatttcttga ctttttccaa attttgtttg tgaaaattct aactttatgg
    20521 tattataata acatgaaaat gaaatgtaag ggcttcaatt tagatgatta tttgatatta
    20581 caacttattt tctataagag aaaggagttg gtagcttgac tcttcgttca cattctgaac
    20641 ggctaatggg gactactatc actatttcat tagtggatga gcaagccgat atctttctcc
    20701 aaaaatcctt tgacttgctc aaagagcttg aataccgctt caacgccaat agtcaagaat
    20761 ctgagttgat ggaaatcaat tatcaagcag gaatatcccc cgtcacggtt catccagacc
    20821 tgtttgagct gatttcactt gggttagagc atagcctagc gctctctagc cacctcaata
    20881 tcagcattgg tcccttaatt caaacctggc gtatcggttt ttcagatgcc aaggtcgccc
    20941 agcctcaaga aattgaatcg gtgctgcctc taatcaatcc tcatggtatc gagttagatt
    21001 cttctacttc tactgtgttt ttaaaacaga aaggaatgaa gatcgatcta ggttgtttag
    21061 ccaaaggata cagtgcggat aaggttgccc aatttcttag gaaagagggg gtgacttctg
    21121 ccttgatcaa tctgggaggg aatatcctga ccattggaaa aaatcaggca agaggggata
    21181 acccatggca aatcgggatt caagacccag ccaatccgag gggaaatcat ttaatgacca
    21241 tccctgttgt caataaatct gtcgtgactt caggcattta tgaacgtcac ctgaccgtcg
    21301 atggacaaga ttaccatcac atttttgaca gtcaaacagg atatcctgtt gaaacggaac
    21361 tagcgagtct aacaatcatc tctgataaat cagtcgatgg cgaaatctgg acgactcgac
    21421 tctttggaga aagacctgct tctatcttct ggcaagtcga aagtttggag ggcatcgaag
    21481 tcatcctcat cgataaagaa ggccacctaa gctgttcttc aggaattcct actctataga
    21541 gacaactgtt tcaatggaat tttaaaattg tattatgtaa aaagagaaag gaaatctcat
    21601 gttaaaactt attgctattg ttggaacaaa ttcaaaacgt tctacaaacc gtcaattgct
    21661 tcaatacatg caaaaacact ttgctgacaa agctgaaatt gagcttgttg aaatcaaggc
    21721 cattcctgtc ttcaacaaac cagctgacaa gcaagtacct gctgaaatat tggaaattgc
    21781 tgctaaaatc gaagaggcag atggcgttat tatcggtact cctgagtatg atcactctat
    21841 tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat ggtatttacc cacttttgaa
    21901 caaaccaatc atgattacag gtgcttctta cggtacgctt ggttcatctc gtgcccaatt
    21961 gcaacttcgt caaatcttga atgctcctga aatcaaggca aatgttcttc cagatgaatt
    22021 cttgctctca cactctcttc aagcatttaa cccaagtggc gacttggttg accttgatgt
    22081 tatcaagaaa ttggatgcca tctttgatga cttccgtatc tttgtaaaaa tcacagaaaa
    22141 attacgtaat gcacaagaat tacttcgcaa agatgctgaa gactttgact gggaaaattt
    22201 gtaagatagg agaccaaaaa gaatgaaatt tgttggactt gttggatcaa actacgatca
    22261 atcatataac cgtaagctct tggaatttat ccgtcgctac ttcaaactca aatttgaatt
    22321 agaagttctt gaaattgacg aagttccaat gtttaaccaa gatgaaaaat gggatgaaag
    22381 tttccaatta cgttatttat ataacaaaat tactcgtgca gatggtgtta tcattgctac
    22441 tcctgagcat aaccacacta tctcagcttc actcaaatct gtacttgaat ggctttcata
    22501 cgaagttcat ccatttgaaa acaagcctgt tatgattgtg ggtgcatcat actatgacca
    22561 aggaacatca cgtgctcaag ttcaccttcg taaaatcctt gatgctccag gtgttaatgc
    22621 ctacacgctt ccaggtaacg aattccttct tggtaaagct aaggaagctt ttgataacaa
    22681 cggaaatatc accaacgaag gcactgttaa attccttgaa acttgcttag ataactttgt
    22741 taaatacgta ggagtcgttt cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt
    22801 ggattgtgga aaaccaatcg ctacaaccat cacagaagtt gaccctgacg atccagaatg
    22861 ggtagaaaaa gttgcagcaa tcactggtgc tgtttctggt gatacctatg tcaaattgga
    22921 ccacggtatc ctaacagtta accaaattga tatgttcttg aaagctatgc catttgaatt
    22981 gacatacgct gacgacaaca accaattcct ctactacaac aacgctcacc aagatccaga
    23041 cactatgttc gctaaacgtg taccacctca atcaggtagc cgtatgtcga ctgttcatgg
    23101 ttctcttcca ccagcacgta tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg
    23161 aaaccaagaa tacgtccgta cgatcgttcc aggttctcct gcaggtgtta tcaacactca
    23221 caactaccaa gcaatgtact atcctgatgg atcatacgct ggtatcaatg aaatcgtctt
    23281 taacttccaa ccatggcttg actggtacct aaaagagact ggtcaacgtt tggtgggtgg
    23341 tagcggacca tttgctcctg ctgccggagg tcatggagac gccgatgcta cttctggcgc
    23401 ttctgattca ggggatgctg gaggccacgg tggtgacgca gacgctacag ccggtgcaag
    23461 ttactaatga tagtttttag gaaccattat ggttcctttt tagcgaaaaa agactagcaa
    23521 acacaaactg ctagtctctt tgttatcgtt tcatctatct ttgttaaaag aaagaataca
    23581 tattatgaat ttggatcatc aagactacgg ccatgtaatc ctttttcacg ttgtacttgg
    23641 cgtagttttt ctggtgtaac atcgtttcct tcttcgtcca caattttgat tccttcaatg
    23701 tggtgacgaa cagcgcggcg ataaccttcg atgtactcct cacgtagttt ggcttgttcc
    23761 actttttctt ctggtgttaa gccttctgtt tttttctttt tagcaagctc attgatacga
    23821 gcaatttttt tcggatccat ttcttctcct ctgtaataag ataaagtccg tttatcaaat
    23881 tttatttagt gttaatttgg ttaaaacaag caaacttagc tgctttcttg gttagttgtg
    23941 acaagattgc caaacgattt tgacggacag cctgatcttc agccattacc atagtatttt
    24001 caaagaaagc atcaatgact gggctaagcg caaagagttg tttcaattgc tgacttgcag
    24061 gtcctgataa aacgagtgtt tctactgctt ctgccaaagc tttttcttgg tcattctcaa
    24121 atagtgctga atcaactgta gcaacccctt ctgccttctc agccaggtta aaggcacgag
    24181 aaagtgattc aacagatggt ttaaaatctt cttccttgct tacttctacg agagcacttg
    24241 ctgcttccaa catatctgcc acaacaaagt ttgaacctgc aagaactgct tccttgatat
    24301 cttttggagt agagcccatc atcttatcaa cacgagcctt gataaagtcc ataacctctg
    24361 ctttattttc ataagtcaaa ctgtcaaatt tcaatgcata aaggctatca atcagctcat
    24421 ccatagcaat gtgccaacca aaggcatcca agatacgaac cacaccttga gttgcacgac
    24481 gaagggcata agggtcatta gaacctgatg gaatcaatcc tactgagaag aaactcaaaa
    24541 tcgtatccaa tttgtctgca atggctagaa ctgcaccgac cttgctctct ggaagttctc
    24601 cttcagctga tgtaggcatg tagtgttcac gaatagcagc tgccaccgct ggagtttcac
    24661 cagcaagaag ggtgtatttt tcacccataa ttccttggag ttcgtcaaat tcaccaacca
    24721 tacctgtcaa caagtcaaac ttgtaaatgg ctgctgcacg agcaaggtca actgtttcat
    24781 ccactgacaa accagctttt tctgccaaaa gtacagtgat ttgacccgta cgaatcatgt
    24841 gttcacgaag ggaaccaatc ttctcatgga aggtgacatt gtttaatttt tcaacaagat
    24901 ctgaaatcac caatttttgg tcttcacgcc agaagaattc tccgtcttcc aagcgggcta
    24961 ccaagacttt ttcatttcct ttgatgacat ttttcaaacg ctctgcgttt ccgttacgaa
    25021 cagaaatgaa gtttggcaag agttttccat cttgatcacg aacaacaaag taacgctggt
    25081 gttccttcat agaagtcacc aagacttctt ctggaacttc aaggtattta gcatcaaaac
    25141 ttcccatgaa ggcagttggg tattcaacca aattcaagac ttcattcagc aaatccgcat
    25201 caatttcgat acgtacacca tgttttgcct caattttctt gatttggtca acaatcattt
    25261 gctcacgttc acatggatct gcgattacaa actgcttacg aaggtcttct tcatagctca
    25321 atgctgactg aattttggtt tctttcccca agaaacgatg gccacggctc acacgacctc
    25381 ccttgatatc aaggaaatcc aagtcaaact cttgctcatc caagagaaca gttaaagtgt
    25441 gaacagggcg gatgtattca aagctatttc cagcccagtg catgctgaca gggaaagtca
    25501 atgacttcaa gacatctaca acaccaggaa caatggcttc aactgcttga ccaacttctt
    25561 ccttagtgac atagacatat tcttcaccct tgatttcacg gaattcgata tcttcaacag
    25621 tcaagccttt tccacggaca aatccttgag ctgctttggt gaagtttcca tcactatcca
    25681 aggcaatttc ctttgctggt cccttgaaat cttctgtcaa atcagactgt ttgtctgata
    25741 aaccagtcac acgaacagcc aaacgacgtg gtgttgagaa ggtttgaatg gcttcaaaag
    25801 acaggcggtt ttccttgagg aaggctgcca ttttttcgcc tagttgtttt tcacttggtg
    25861 tgacaacata ggctggtaat tcttcaagac cgagttctac taataagttt tttgtcatgt
    25921 tttttctccg aaaagtatct ttttattttc cagtttgcct tatgtgattg gcacgcaagc
    25981 aaccaacttc gttgtttcat tgctaaaatt ggagccaaaa gtctccaatt ttgcctagta
    26041 tccttagttt cactaaggat accttcatca ctgcggcaac tgactcaggg ctcactctgt
    26101 tcgcccattt tcgtaatttg tcactctctt tattctgcgt cttctgctag gagtttagct
    26161 cttgtttctt catccaaaag tgggtaacct aggcgtttgc gttctgcaac aaaggttttg
    26221 gctacaacac gggccaagtt acggatacga gcgatatagc ctgcacgctc tgttacagat
    26281 acagcaccac gcgcgtcaag cagattaaag gtatgtgaac atttgagaac atagtcatag
    26341 gcagggtgta ccaagccttc ttctaatgca cgaccagctt ctttttcaaa cttatcaaag
    26401 ttttcaagca acatttcttg gtccgaaatt tcaaatgaat attttgagtg ctcatactca
    26461 ggctggataa agatttctcc gtattttaca ccatcagccc actcgatatc atagacagag
    26521 tctacttctt gaatgtaaga agccaagcgc tccaaaccat aggtaacttc cgcagtcaca
    26581 gggccagttg ccaatccacc gacttgttgg aaataagtga actgagtgat ttccattccg
    26641 tcaagccaaa cttcccaacc aagaccagct gaaccagttg atgggttttc ccagttgtcc
    26701 tcaacaaaac gaatatcgtg ctccaaagga ttgattccca atttttccaa agactcaagg
    26761 taaagttctt ggatatttga tggagaaggc ttcatgacca cctggaattg gtggtgttgg
    26821 tagagacggt tagggttttc cccataacga ccgtcagcag gacgacgtga tggctctaca
    26881 taagctgcat tccatggctc aggtccgata gcacgaagga aagtgtaagg actcattgtt
    26941 cccgcacctt tttcattatc ataagcctgc ataagcatac aaccttggtc attccaaaat
    27001 tgttgcaaag taaggatgat ttcctggaaa gtcaatttct tagacattgt ttactccttt
    27061 ttatataaat tacttgcgac atgagtctgc ctcgtcgatc atacgaggca agacgagtta
    27121 gtactgcgtc tagctcaggc actctagtgc tgagcgtggg gcagtccgac tgtaaggagg
    27181 tttctgccac tgatgcagta aaatgttaat ttcttagaca ttgaatactc cttaataaaa
    27241 aatgatttct tgcgacacga gtctgcctcg tcgattatac gaggcaagac gagttagtac
    27301 tgcgtctagc tcagcaccct agtgctgagc gtggggcagt ccgactgtaa ggaggtctct
    27361 gccactgatg cagtgaaatg ttaatttctt agacattgtt tactccttta gtttttatat
    27421 ttctttttca attaatttct gctgaacaaa ccaatctaac aagggaaaag ttttttctgt
    27481 atttgcccat aaatgataag aatctaagac cgcttgtaca ctacctaaat tttctaccaa
    27541 cttatctact gtcaaaaagc ttcgccagta ttcataaaaa atacttgcat agttcttatc
    27601 ataagtcgaa gaaccaaaat cattcaatga atgccaacca tacttcttct gaaaaagttc
    27661 tacgagagat tgattacaaa ttttttccgc ttgaaattcc tcttctgtaa agaaatactt
    27721 gcgactaata tattcaacca tcccctcttc gaaccagata taagagtcat aaccatcaaa
    27781 atcatctaaa aaatgctccg accaatgagc taactcatgt cctacaatct gtaagaggaa
    27841 attttcagat aaagaatgat agtgactttc tattgcttga gtttgctcag aacactcgta
    27901 gtccatcaat tgatacaaat acaactcttt ccaaacagct aaatcaggcg ccataaccat
    27961 tcgtctatta tttgtatagg ctggaacagc gctttcccta ataatctgtg tagcagcatt
    28021 aaaatctgac caaataacgg cttgcggtaa atcacagact gcaagttcat tctttaaaaa
    28081 agattgataa tctttcaact tttcagtatt tcttactaca aaatcacgaa atgtagctag
    28141 ttgactatcg tcttttacaa gataaaggtt gtccacggct ctcctttctt tcacacaata
    28201 gactgaataa gcaaaagaac cgcgtccgac aatcctaggt tgatttaacc taggggcgtc
    28261 agaaacgcgg ttccacccta atttattact tcattgtttt tgaaaatact acagaaagcg
    28321 ccagctcatt attttgccct acttggctcc cactatccca agctcgcttg aagaacgcca
    28381 taagactttc tttcctgctg actattatat caaaaattag aataatgtac aattcttttt
    28441 atgattttct agaaatccac atcatcaact cgtggagcac ccgattgaac agcaatcgtt
    28501 tttaaggttt ctctctcctc atgactcagt tcaattccaa agcaatcaag attagcttga
    28561 atacgagagg ttgtgacaga ttttggaagt ggtaaaaatc cttctgccaa gctccaggcc
    28621 aaggctatct gagcaatcga ttttccgtga tttgctgcga tttcttgcac ttgcttgcta
    28681 tcaaatagtt ctccctgacc aaaaggcccc caagcttcca ataaaattcc cttttcacga
    28741 cagtaagcta cgacttgatc ttgatacaca cctggcgcca agcgaacttg attgaccgca
    28801 ggaacgatag ttgcagtttc aagcaaggca tccaaatgat ggggaagaaa attgctaacg
    28861 ccgatagcac ggattttccc ttcttgatag aggtcttcca tcgctctcca aacttccgca
    28921 ttgcgagttt tccatgcgtc attttctctg agcggttttg ggttcggcca atgaatcaaa
    28981 tacaaatcca aataatccaa gcccagtttt tctatagatt tttccaaagc ttgacgagtt
    29041 tgctcatagg tttgctgact attccaaagc ttggtagtta cgaacatttc ttcacgtgga
    29101 actccgctat ctttgattgc ttgaccaaca ctttcttcat tctgataaat cgccgccgta
    29161 tcaatatgac gataaccagc cttcaaggct tctaacactg catgataggc ttcttctcca
    29221 tccttagcct taaaagttcc aaatcccaat actggaattt ctactccatt atttaattga
    29281 taggtattca tatgcttctc cttctatttt attcatcaat tatagcataa gacatttttt
    29341 aagtagtact atcttctgta aaaaataagt ctgtcaaata tctaacagac ctattttttc
    29401 ttgcttattc atcacgacta tagtacagct catgagcttt taggcgagta ttgagcatct
    29461 ctggtatggt cacaaaggta taaccttgat ttttcaaata ctcaatgacc cttggcaagg
    29521 cattgactgt cggactgtga atatcatgca tcaaaacgat agagccgtta gctacttgat
    29581 gctgaatttc tgtcaaaata gatgcttcat ttttactctt ccagtccaga ctatccacat
    29641 cccacatgat aaagctcaaa tccaagctat tgcgaatatc atctgtaata gcaccataag
    29701 gtggacgcat gagtttagaa ctagaaccca gcactttagt tagcacatcc tcagtatcag
    29761 taatctgctt tttagcttca tcaagagaga gttgcgagag aatcggatgg ctccaactat
    29821 ggtttccaac aacatgacct tcagatttta tcctcttcac caagtcctca ttcccagaaa
    29881 catttttccc aagcacaaag aaagtcgctt taatatcata tttagctagg gtctctaata
    29941 cctgcggggt cgttgctgga tttggaccat catcaaaggt tagagcgaca actttttgat
    30001 atttcttatc aaagtaagat tgatacaagg ccgcatcttt ttcgagtaag tacgaagatt
    30061 ggataacatc aaagaaagca gatactggca aggctatctc ttctaaattt tcaagcacag
    30121 gacttgaata aaggataatc tgactatcct tgtaatcaaa attccatgca gacaagtctt
    30181 ggtcagagaa gctttttaca atctgctcac tctggtcttg ctctattttt ttatcctcta
    30241 tgaaggaggt caactctttt atcagctgtt ccttagcctt actagcatct gaaaacagtt
    30301 ggtcaagtgt aaaaggttgc ccatcttctg ttaagtgaac ctttcctaga ctggtctttt
    30361 cagtctcttc aaccttaaaa gcaactaaat catagatttg tttggtcaca ttacgattaa
    30421 cgactccctt taaacctgac tcttcttgct ctgtatagta gaaaacaaga ttgtccttac
    30481 tttctagctt gtccttaaca tcttgattta tcaactccct aacagaggaa atcactttct
    30541 ccccttggag aggataatag gcaatcactt cggcttgccc ctgacgaaaa tgctccttct
    30601 gatttccctc actcaattga tcatctttct cttttttgag cgattcaatc ttttgctcaa
    30661 aacttttttg ctggtagatc ttaaaagcaa taaatccgcc taataggcaa atagaaattg
    30721 ctaagatacc aatcaaagcc aataatacat gtctcgtttt cccgtgtctg ccacgtccta
    30781 gtctactttt attcatattt atatcataac aaatttgagc aataatttca atgatacaat
    30841 ttggcaatcc acaattcctc tagcaagcca aagcatctta catcaactcc aacatccgta
    30901 tctgtagaga ttatgtagtt ttctatctat ggaatttcta gtaaattgaa gctagaatag
    30961 tagacctata cttctaaaac attgttagaa atcgatttga ttgtcctgat cgatttgtcc
    31021 tgttcttatt tcattttact ataaaactat gaaaagctag gtcatctgag aagtaattac
    31081 tatcgacaat tgcgatagcg tatactggtg cgatttgttt gtagctctgg tgggtatcac
    31141 cttcacgttg gcgaattttt tctaggtttt gattaacctg actgcacaga taagcccata
    31201 ggcgattgat gaaaaaattc tgatgatgaa cctgaatttc gatgataact tgaattccat
    31261 tatctaactc cgccaagacg tctatactag tatagaaatc ctgcgctgag taggacatgg
    31321 aaggcaagac gtgaatgtta cttccctcca aaatcgtcac attttttgct ggcaagtcca
    31381 gcatatcgcg gataaattga caaatcatta gttgggctga tacccggatg tctgagaatc
    31441 ctccttttcc tccttctatt atagcacatt tttaaatcta ggtttgctag attctatgct
    31501 tctatctatt tattcggaaa agaaagcttt tcttcagaag aaagctaata gcttatttga
    31561 aattttctcc tctctgttgg atagtcccgt ctatctatgt tataatgaaa gaaggattta
    31621 aaatcggaaa aggagtattt atgctaaaat taggtgtcat cggaactggc gctatcagcc
    31681 atcatttcat agaagcagcc cataccagtg gagaatacca actggtcgca atctattcta
    31741 gaaaactaga aactgcagca acctttgctt ctcgctatca gaatatccaa ctattcgatc
    31801 aattagaagt cttcttcaaa tcttcttttg atttagtcta tatcgccagt ccaaactcct
    31861 tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa acatgttatt ctcgaaaagc
    31921 cagctgtcac tcaaccacaa gaatggtttg atttgattca aacagctgaa aaaaataact
    31981 gttttatctt tgaagcagct cgtaattacc acgagaaagc ctttactact atcaaaaact
    32041 ttttagcaga taagcaagtg ttaggagcag atttcaacta ttccaaatac tcttccaaga
    32101 tgcctgactt gttggctgga caaacaccaa atgtcttttc agaccgtttt gctggtggag
    32161 ccctcatgga tttggggatt tatcccctct atgctgctgt tcgtcttttt ggaaaagcca
    32221 atgacgcgac ttaccatgct caacagcttg acaatagcat tgacctaaat ggagatggta
    32281 ccctcttcta cccagactat caagttcaca tcaaggctgg aaaaaacatc acttccaatc
    32341 ttccttgcga gatttataca acagatggaa ccttgactct caacacgatt gagcatattc
    32401 gctcagctat ttttaccgac caccaaggaa atcaagtcca gcttcctatc caacaggatc
    32461 ctcatacgat gactgaggaa gtcgctgcat ttgcacacat gatccagcaa ccagatctga
    32521 atctctacca aacttggctg tatgatgcag gctctgttca tgagctacta tataccatgc
    32581 gccagactgc tggcattaga tttgaggcag aaaaatgaaa accaaactac cgactgaatg
    32641 gcaagaactg agtgaccaac tcggtttcca agaattcacc ctcattcaaa ctcaactatt
    32701 tgagcccctt cttgctggag aaaacctcct aggagtgagc caaaccggaa ctggtaagac
    32761 cctagcgtat ctcctaccaa gtcttctcag actacaaaag aaaaaagccc aacaactctt
    32821 gattctagca ccaaatacgg aacttgctgg acagattttt gatgtatgta aaacgtgggc
    32881 agaagctatc ggattgactg ctcaactctt cctttcaggt tcaagtcaga aacgacaaat
    32941 tgaacgcctt aaaaagggat cagaaattct gattggaact cctggccgta tctttgaact
    33001 cattaaactt aaaaaaatca agatgatgaa tgtggaaacc atcatcctgg atgaatttga
    33061 ccaattacta gatgattctc agattcactt tgtagaaaaa atcactcact acgcacctcg
    33121 tgaccaccaa ctggtctaca tgagtgccac gaccaagttt gaccaagaaa agattgtgcc
    33181 gaatacacgc actattgatc tctctgatca aaaattggac aatatccagc atttctacat
    33241 gcaggtagac caacgtcatc gagtggatat gctacgaaaa ctggctcatg tagaggattt
    33301 ccgtggtcta gtcttcttca atagcctgtc agaccttggg aatgccgagg aaaaactaca
    33361 gtatcgtgat atattggctg tttccctcgc tagtgatgtt aatgttaaat ttagaaaaat
    33421 catcttagaa aagtttaaag ataaccaact aaccctgctt cttgcaactg accttttggc
    33481 tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac tttgatattc ctagagatag
    33541 cgaaacctac acacaccgtg ctggccgtac tggtcgtatg ggcaaggaag gttatgttat
    33601 cactctcgtc actcatccag aagaaatcaa aaaacttaaa aagtttgcaa gtatccgaga
    33661 aattgtccta aaaaaccaag aactctatat caaataaagc cctattgctc tatacacatc
    33721 cagtgtatgg agctttttta taagcaattc aattttatac tcatctgctt tcaaaaagca
    33781 ttctagtcca tttccgatta acgatggact ttatcacctc cttctccagt ccttgtatga
    33841 catcttccaa agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca
    33901 cttgttcaat ggggttcatc tctggtgtgt atggaggaat aaatgcaaag ccaatattag
    33961 tcggaatctt taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaaaat
    34021 aatcatatgg ataagcttgt gaaagctctt ctaaaaagac gttcatccac tcagtattac
    34081 atccaccagc tattaagaaa aatgattcgc ttgtataggc atcaacagct ccataacaat
    34141 agcgaaattc tcgtatatag tgactatgga catgtggacc tactcctatt ggagaccaac
    34201 aagatcccag tttactgatt ctaccgaaac cagcctcatc ttggtacatc aagcgaacct
    34261 tatgaaaaca tctactagtt ttaaagcgct ttcttgtctt cttgaattga gattttattt
    34321 ttagacgcga caatggtttg agcgtctgct ttcctaggat gttctggacg tggcataata
    34381 tttcgccaac catggcgctt caacagttga tagaaggcat cacgtgtgta ggaacgacct
    34441 aactcctttt tataagcctg aaataaggca tcaattgtaa caaattctcc tgcctctgca
    34501 gccttcaaat ggcgggcaag aaagactttc ttttcctcaa ctgtaatata tgcatggtta
    34561 cgaccaccac gtgtttcttg aaggagagag tcgagtccga actcctcata tttttttaca
    34621 ttttgctaaa tcgttgtttg attacagtct aaaagctcta taatctcttt ataagatttg
    34681 cccatcagac gaaatagaac gatttgaagg cgtttatgat atttagctgt acgagagtct
    34741 tttaaaagtg ttttgatggt ttggatttc
//
LOCUS       DAVIME010000020        34465 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVIME010000020 DAVIME010000000
VERSION     DAVIME010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.020"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(202..492)
                     /locus_tag="VV588_001023"
     CDS             complement(202..492)
                     /locus_tag="VV588_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083380.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(480..731)
                     /locus_tag="VV588_001024"
     CDS             complement(480..731)
                     /locus_tag="VV588_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU7083381.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            935..1138
                     /locus_tag="VV588_001025"
     CDS             935..1138
                     /locus_tag="VV588_001025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083382.1"
                     /translation="MKIKEQTRKLATGCSKHCFEVVDKTDEVSSKHCFEVVDRTDEVS
                     SKHCFEVADRTDEVSNIYTARRR"
     gene            complement(1175..2059)
                     /locus_tag="VV588_001026"
     CDS             complement(1175..2059)
                     /locus_tag="VV588_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU7083383.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(2204..3355)
                     /locus_tag="VV588_001027"
     CDS             complement(2204..3355)
                     /locus_tag="VV588_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU7083384.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(3501..5267)
                     /locus_tag="VV588_001028"
     CDS             complement(3501..5267)
                     /locus_tag="VV588_001028"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU7083385.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            complement(5350..8466)
                     /locus_tag="VV588_001029"
     CDS             complement(5350..8466)
                     /locus_tag="VV588_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU7083386.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRSAGIPLSLA
                     EVEVYTYK"
     gene            complement(8476..10770)
                     /locus_tag="VV588_001030"
     CDS             complement(8476..10770)
                     /locus_tag="VV588_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU7083387.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(10829..11629)
                     /locus_tag="VV588_001031"
     CDS             complement(10829..11629)
                     /locus_tag="VV588_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU7083388.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(11626..12399)
                     /locus_tag="VV588_001032"
     CDS             complement(11626..12399)
                     /locus_tag="VV588_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU7083389.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(12424..12894)
                     /locus_tag="VV588_001033"
     CDS             complement(12424..12894)
                     /locus_tag="VV588_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7083390.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(12885..13316)
                     /locus_tag="VV588_001034"
     CDS             complement(12885..13316)
                     /locus_tag="VV588_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7083391.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(13309..13749)
                     /locus_tag="VV588_001035"
     CDS             complement(13309..13749)
                     /locus_tag="VV588_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU7083392.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(13761..14399)
                     /locus_tag="VV588_001036"
     CDS             complement(13761..14399)
                     /locus_tag="VV588_001036"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU7083393.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(14514..15917)
                     /locus_tag="VV588_001037"
     CDS             complement(14514..15917)
                     /locus_tag="VV588_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU7083394.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            16093..16866
                     /locus_tag="VV588_001038"
     CDS             16093..16866
                     /locus_tag="VV588_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU7083395.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(17994..19499)
                     /gene="adcA"
                     /locus_tag="VV588_001039"
     CDS             complement(17994..19499)
                     /gene="adcA"
                     /locus_tag="VV588_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU7083396.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVTKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYVEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(19509..20315)
                     /locus_tag="VV588_001040"
     CDS             complement(19509..20315)
                     /locus_tag="VV588_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU7083397.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(20308..21012)
                     /locus_tag="VV588_001041"
     CDS             complement(20308..21012)
                     /locus_tag="VV588_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU7083398.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVSHA"
     gene            complement(21012..21452)
                     /gene="adcR"
                     /locus_tag="VV588_001042"
     CDS             complement(21012..21452)
                     /gene="adcR"
                     /locus_tag="VV588_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU7083399.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(21607..22875)
                     /gene="dltD"
                     /locus_tag="VV588_001043"
     CDS             complement(21607..22875)
                     /gene="dltD"
                     /locus_tag="VV588_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU7083400.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(22868..23107)
                     /gene="dltC"
                     /locus_tag="VV588_001044"
     CDS             complement(22868..23107)
                     /gene="dltC"
                     /locus_tag="VV588_001044"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU7083401.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(23121..24365)
                     /gene="dltB"
                     /locus_tag="VV588_001045"
     CDS             complement(23121..24365)
                     /gene="dltB"
                     /locus_tag="VV588_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU7083402.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(24362..25912)
                     /gene="dltA"
                     /locus_tag="VV588_001046"
     CDS             complement(24362..25912)
                     /gene="dltA"
                     /locus_tag="VV588_001046"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU7083403.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKSDSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     ITDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(25933..26064)
                     /locus_tag="VV588_001047"
     CDS             complement(25933..26064)
                     /locus_tag="VV588_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU7083404.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(26295..26999)
                     /locus_tag="VV588_001048"
     CDS             complement(26295..26999)
                     /locus_tag="VV588_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU7083405.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPISNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(27069..28895)
                     /gene="glpO"
                     /locus_tag="VV588_001049"
     CDS             complement(27069..28895)
                     /gene="glpO"
                     /locus_tag="VV588_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU7083406.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKSDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTSAANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(28937..30445)
                     /gene="glpK"
                     /locus_tag="VV588_001050"
     CDS             complement(28937..30445)
                     /gene="glpK"
                     /locus_tag="VV588_001050"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU7083407.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(30604..32031)
                     /locus_tag="VV588_001051"
     CDS             complement(30604..32031)
                     /locus_tag="VV588_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU7083408.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSENENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            32196..33068
                     /gene="hslO"
                     /locus_tag="VV588_001052"
     CDS             32196..33068
                     /gene="hslO"
                     /locus_tag="VV588_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU7083409.1"
                     /translation="MNKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            33055..34035
                     /gene="dusB"
                     /locus_tag="VV588_001053"
     CDS             33055..34035
                     /gene="dusB"
                     /locus_tag="VV588_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU7083410.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(34265..>34465)
                     /locus_tag="VV588_001054"
     CDS             complement(34265..>34465)
                     /locus_tag="VV588_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU7083411.1"
                     /translation="NANGSMATGWLKDGDTWYYLEASGAMKESQWFKVSDKWYYVNGS
                     GALAVNTTVGGYRVNANGKWVN"
BASE COUNT        10335 a         7581 c         5953 g        10596 t
ORIGIN      
        1 atctgaatct ttgagatgag ctttataaat cgcttttttc agtttttgca ctggtgtttc
       61 gataaactca aactttttag ccgtggtatt gcctgatttt atagtatatt gaaactagaa
      121 tagtacacct ctacttctaa aacattttta gaaatcgatt tgactgtcct gatcgattta
      181 tcctgttctt atttcatttt actatatttg agccacttcg tctttaacgg ctttattcat
      241 aagctcttgt aatttttctt tactatcaat tacttctgat tttccgttgt aatttattgt
      301 aataggtttt aacttaccta atttctcgac acgctcatta atttgatctt ttttgaaggc
      361 tgcatatgtt tttcctaaga ttttttcgaa aatatattta tcagatagcg gtttgccttc
      421 ttcttcagct tggtttttgt attgatttga aacataagga acaaatcctt catagtaacc
      481 taatgctccc ataagttcaa aagcttgttt tctaattcaa accattgcaa ctcagatttc
      541 agcttttcag ataaatcctg ctcatccaaa taatgacttg aaattagtgc tgaactcgtt
      601 tctgtatcct gtacaggctg agcacccata ccagcaaaaa ataaactcgt tcctagcaag
      661 accgaacaag ctcctattgc atatggcctc aaagaaaaac gctgctttct ctcaaattga
      721 aattctttca tcccatctcc catcattcat tattactgta tattttgtat atcagaaata
      781 gtttgtattc acaaatcttt ctagttattc ccttatcatt cctaattaag ggagataaca
      841 tacaataatt tttagttaaa tgtatatcga tgttttttgt ttttcttaat aaacgcaata
      901 caaaaagagc ctgttgccaa gctctttgta ctcaatgaaa atcaaagagc aaactaggaa
      961 actagccaca ggttgctcaa aacactgttt tgaggtagta gataagactg acgaagtcag
     1021 ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt
     1081 tgaggttgca gatagaactg acgaagtcag taacatctat acggcaaggc gacgctgacg
     1141 tggtttgaag agattttcga agagtattag tctattattt cttctcagcg cgaagggctg
     1201 acaagatttg tgttcggata tcatccacac catttggagt atttggtaaa aagatggttt
     1261 gatttccttt agaggcaaag gtattcaagg tatccaaata ctggttggtc aagaggatag
     1321 acatgatttg ttcttctgtc atgccaacat tggcttcctt gagttcggtg atagactctg
     1381 ccaatccatc cacaatcgcc ttacgttgtt gggcaatccc cacaccatga aggcggtctt
     1441 tttctgcttc tgcttcagct gcagtgacaa ttttaatctt gtcagcttcc gccaattctt
     1501 gtgctgcgac ccgcttacgt tgcgccgcat tgatttcatt catggattgc ttaacttctg
     1561 catctggttc gaccttggta atcaaggttt tcacgataat gtagccgtaa gtggtcattt
     1621 cttctgctac ttggtgttga acctcaaggg caatctcatc ttttttctca aacaattcat
     1681 ccaaggttaa ttttggaaca gaagagcgaa gagcatcttc gatataagat ttaatctgag
     1741 attctggacg tatgagttta tagtaagcat ctgtcacgct ctgctcgttg acacggtact
     1801 gagtcgctac attcatcata acgaacacat tgtccttggt cttagtctca accacaatat
     1861 cactttgcaa caagcgcaac tgaatccgtg ctgcaatcga gtcaatccca aaaggcaagc
     1921 gaatatgaat accgctatta gcaacctttt ggtatttccc aaagcgttca ataatcgcca
     1981 ccgactgctg acgaaccaca taaactgtac tcagtgtgac tatcaccaat aggagcacac
     2041 aaacaatcag aaaaatcatg aaaaatattg ccataatgga acctccacaa gtatttttct
     2101 agtattatag cacatttaaa gaaggctgtg ccgtttttac tgcgattttt cctgaaatgt
     2161 caataattag aggtgaattg tcctattgtc gtccaatctc ttgctaaaat aactctttat
     2221 aaaaggcaat cgtttcttct aaggttggca taaatggatt tcctggtgcg caggcatcaa
     2281 tcaaggcatt cttagaaagg tattcaaagt cgaaatcttt ttcttcaata ccaagttcag
     2341 tcagtttctt aggaatacct actgtctcag aaagcttctc aatctcagca atcgcataat
     2401 cggcacattc ttgatctgat ttaccttcta catgaagtcc caaggctttg gcaacattgc
     2461 ggaaagcttc tggtacacgt ttagcatttt cacgttctat aactggtagc aacatggcac
     2521 agcacacgcc atgtggcaaa ttatatactg caccgagttg gtgagccatt gagtgaacat
     2581 aaccaagacc agcattatta aagctcatac caccaaggaa gatggcattg accatacctt
     2641 cacgcgcttc aatatcatgt ccattttcta cagcacgagg aagatattcc ttgataagct
     2701 caatagcacc aatagacagt ttcttggtta catcataagc accaggtgtt accaaagctt
     2761 caacagcgtg agtcagagca tccataccag tagcagcagt caggccttta ggtttggaaa
     2821 gcatgagttc cgggtcatta acagagataa gagcaaggct attcttgtca accattacca
     2881 tcttaacctt gcgttcttca tcagtaatca catagttaat agtgatttct gcagaagttc
     2941 ctgccgttgt attgatagcc acaactggca agcctttttt agcagactta tgaagccctt
     3001 cataatcctg tggttttcca ccatttgtag ccatgataga aatacaacta gctgcatcct
     3061 gtggagaacc cccgccaaga ctgatgataa agtcacagcc atgttcttgc aaagcagcta
     3121 ccccatctgt gacattttta caagtagggt ttggctctac atcgctaaag atgacatatt
     3181 cgattccttc tgtatccagt ggttttaaag tcttaggtaa aatatcactg ccttcgatgt
     3241 acttatctgt aaccaaaagt gcctttttat agccaagttc cttgatataa ggacccactt
     3301 catttacaac accttttcca ataaggttga ctgccggaac ataaaatgta gccatataat
     3361 tttcctcctg cgcctccgcg ctatctattt aacatcatta tattactttt tgtattcgtt
     3421 tttaattatt tgtgaattgt ttaacaaatc tttttaaaag gataggaggg acgtaagttc
     3481 acctcctata taaacaagtt ttatttatgt agtggtccca acaactgaca tgcacaatag
     3541 tctgctgatt ctagatcttc tgttccaaat aaggaccaat ttttaggtct aaagatatct
     3601 tcctcaggta cattatgcat attgacagga attctcaaca tagaagccaa ggtaatcaag
     3661 tctgctccaa tgtgtccata tgttatggct ccgtgattag ctccccaatt attcatgacg
     3721 tcatagacag acttgaaagc accttttcct gtcaaacgtg gagcaaacca agtagttggc
     3781 catcctggat ctgtacgatt atctaaagta tggtgaacat cttcaggaag ttcaagtgta
     3841 taaccttctg caatttgtag cactggacca acccctttta gaagattgag acgtaccatt
     3901 gttactggca tatccccctt cgtcaagaaa cgagttgaga atcctcctcc acggaagtat
     3961 tcgcggtttg ctggtgggaa gtctgtattt tcaagcatag cctgcacttc actttcttcc
     4021 aactcccaga atggtttcat aacaggtttg ccatctcgag tagcttgacc tgtaccatcc
     4081 aatgtacaag aaccagagtt gattagatgt aagaagccag ctgcagcacg accctctaaa
     4141 gtatgtcccg ttacacgttt aacagcctct gggctccaat aagtacgcac atcagcaaag
     4201 atttgtggag tatttgttaa tagataatta aagagcatag acacaccatt tagtgaatca
     4261 ttctctgtcg caaatacaaa tggttttcga ataccattcc agtcaaactg agtattgagg
     4321 aaagtttcca taaaatctcc atttggaaaa tggtctgtcc actgacgttg accttggaaa
     4381 ccagctacta aagcatgatg accaactgct tcttcctcaa aaccaagttc agcaagtctt
     4441 gggttaccaa ccattaagtc acgtccaatc atgaacatct taataacaaa ttcccattgt
     4501 ctatcttttt cttcacggct taaaacaagg tcttcacggt tatggtcgaa tccttctttt
     4561 acgttttctt tcacccattt gagcgcacgt tcgaactctt cagggtcgta aatactacgg
     4621 tccatacggc gcgtgaactc cgtcatatct accgattcat ttcgcattcc taggtattct
     4681 tggaagaaat ccggatttac aatagaacca ccaatcccca tcgaaacact acccattgat
     4741 aggtaagcag tgtctctcat caagccagtt gcaagagctg cacgcgcata gcgtaaaagt
     4801 ttttctttga catcttctgg aatatctgtg tcactagctt cctgaacatc tcttccataa
     4861 atcccaaagg ctggaatccc tttttgagca tgtgaagcta gtacagctgc aagatagaca
     4921 gctcctgggc gttctgtccc attaaatccc caaatagcat gaggaatatc tggagacata
     4981 tccatagttt cactaccata acaccagcat ggtgtaactg taattgttgc gcaaacattt
     5041 gattttttaa acaactcatg ggaagctgca gcctctggta cacggccaat agtagatgga
     5101 gaaatcacgc attccacagg ttccccatct ggatatttca atgtgcttga aatcaaatct
     5161 gccacacttt tagccatgtt cattgtttgc acttcaagtg attcgcgtac accttgacga
     5221 cgaccatcaa tagtcggacg aatcccaata cgtggatgtt gaatcatact attttcctct
     5281 tatttttctg tttctttcat actaccatct ccattatatt tacggtagcc tgggtgataa
     5341 tttttaaaat tacttataag tataaacctc tacctctgct aaacttaaag gaattcctgc
     5401 gcttctcaaa gaaattctaa ccttttttcc cttcagtcct tttaagtcta tggatagatt
     5461 attgctttct aaactgtcaa tatgttgtgt aaaaacttca taatcatttg aatcatatat
     5521 aataatatca aaatttgata atctctgaat ttcagcatct gttctattat aaataattaa
     5581 cttttctaat tcttcggttt gtgctaaatc tatctcccac catgaaggag aatcttcttt
     5641 ggtatgagtc actgaatgat gaccataatc tccgttttta tttccatcaa ctgctagacg
     5701 agaaaaacca ttgtaatccg ttgaactctg tcgagtttct tttgttaatg caatattaga
     5761 aagtttcttc ggagttctct ttgaaccata gacttcaact tccgctaaac ttaacggaat
     5821 agctgctgat tttaattcta ttttgactag cttagcccct acagaaggta cttttaaaga
     5881 taacaaacca tcaactactt tatcaaaatg tcttctaaaa acttcttctc ctgatgaaga
     5941 tagaaaaata acatcaaaat tagataaacg ctgaggttcg gcatctgttc tattataaat
     6001 atcaacttta gaaaccgtaa actcttctcc cagatcgacc tgccaccaag cgttagaatc
     6061 tgccttagta tgagtcaccg aatgatgtcc gtaatctcca tctttattac catcaactgc
     6121 taaagcagct acaccctcat aattggttga actttgagta gctaccttat ttgtagagac
     6181 tactttatct tctgttattt tatctatatc ctcttcagat tgcttaccat ctgattctct
     6241 aaaaacctct acttctgcta aactcaaagg cactccactc gttagtaatt taactttaat
     6301 ataccttgct cctttttctt tgaaatctag actaacagat tcacccgaca aattattaac
     6361 atgtttctta gcaacttcgt ttctattatt gtcatataga atcacatcaa aattagatag
     6421 acgttgagtc tcagcatctg tgcgattata aattttaaca agcccaactt tatccatttt
     6481 tttcaaatcg acttcccacc aagagggatt atctgcccta gtgtgtgtta ccgaaccaga
     6541 gttaaaatta ccatttctgt taccatccac agctctatta gggtctccat tgtaatctac
     6601 agaactttgt gttgttggtt ttgcatatgc tatattcaaa ttaccatcat taaatttatc
     6661 tggtgttggg aaagagactg gacctgtccc ctcagtattt atagacatct ctaccattcc
     6721 attatgatta accgtaatgg tataaacatg ggtattctca tcccaatttt ctgtataagt
     6781 ataatgattt ttatcgccac ttatatttat ctgaggttta tgaccagtat gcccttttaa
     6841 tgtaagtgtt gttgtcctaa agtcattatc tacaggattg atggaataat ttttgcttat
     6901 ccagttcgct aactctaatt cttctttctt ccaacttttt gatgcatcaa aatttcctga
     6961 taatgcccac atagctgtct tatctgtcct gtaattattc aataaaatat gtaaattatt
     7021 tggattttct ttaacaacag cgtaagtatg tggcgtcaaa tctaacgata acgactttgt
     7081 attattagta tacataggca acattacttg ctgattttta ttgatattag cattactatt
     7141 ataaatatac caggaattac ctacacgctg agcataccca tctccttcat aaagttttgg
     7201 ataaagcgag tttaaatagt tgactttact agacaattcc tcactatttt tagtcaaaat
     7261 ttttgcatta gggaatatag atgaaatctt ttccttatca attttctcat gtattacagg
     7321 aagaatatga tatctcccat tattatataa aggcattgtt tcatcattcg aataaagtcc
     7381 ttgataaaat ccgtttaatg aactaatcct accttctcca ttccaaaata cagcttttgt
     7441 tctatttaca acttcttcct tacttggagc tggattttgt atagcatgtc taaagaaagg
     7501 aataatacct ttagtaaatg ctggagttgg tacatcattt gtcataaatg tatacgcggc
     7561 acattcgaaa ttataaactg tgcctccccc agtatataca ttcatcattt ccatagcaat
     7621 cattgattct ggttccgatg cataggatct catatcccta gctcttccag tttcaaatgt
     7681 gtttgtataa tgtttttccc accatttcca tgtatctgtt gatgagcccc agttatcaca
     7741 taagccactc aaccaaaatc cactaacgat agaatctgta cccgcatcat ctcttattgg
     7801 cgtattttta gttgccaaca ccaaattttt atgatatttt tgactcgctt caaagaatgt
     7861 cggatcattc ataatagttt cccagaacca tttttcatga tcatgccaga taaaatgcgc
     7921 tccatatttg gcacaaactt ccaaatattt agcactatgc ggagctaact ggttattgta
     7981 aatccaataa ttctcaatat ttaaaacacc ttttaacaca ctatactttt ggaattgttc
     8041 atctaaccac tctggaggaa ctgtattacg ctctccagcc gacataataa ccaagaaaac
     8101 tggaatgttt agactttgag cttcctccaa catcttgaca taccattctc tcaattcttt
     8161 cgtatctcgt ggaatacaac ttgttggttt acagactttt gcaggatgaa gttcaatcgc
     8221 tgcatatggc tttacatctt caggaatagc ttcccatgct cccttcaatg tgttccccca
     8281 ccataatccg ttaccattat cattgccata caacggagaa agcaacaatg gcgattcatt
     8341 attaatcgtc gttctcattt gaacacgatt atcagcctta actcctgcta acaatccaaa
     8401 acataacatc ccaatacata caaacaatat tgtgattaat tttcttttta ttttttcttt
     8461 attcatgact tatacctaaa aatttaactc aataattttt tctgaattaa ataccaattc
     8521 aatattttgt acatcagtat ttttgccata tattcttact cttacttttt gatctttgtt
     8581 tcctccttcc aattttagga atgttatatc cccatttttc caagcaaacg ataccttata
     8641 tcctcctctt actctgaaac ctttcacttc tccttctgac caagcagaag gtaaagctgg
     8701 aattagtgat aaccaattat gatggctctg tactaataat tcacaaattc cactcaccaa
     8761 acctaaatta ccatcaattt gaaatggtgg atggtcaaga aataaattgc caagagtcgc
     8821 attatttaac aaaccattaa tctggttata agcaggttca ccttgatata gtctcgcaaa
     8881 aaaatgaatc agccatgcag cactccaacc tgtttgtgta ctagcatgca aaccacttac
     8941 taaccaatta ttaatcgctt gctccctctc ctgtgaagat aaaaaattag cgtttgataa
     9001 tctcctattg atagtgattt tagctgcttc tgctaattcc ggagttttat gaatatcaat
     9061 ctcattataa ggataaagcc caaatagagg tgaaatgtgt ctatgcccag gctctacttc
     9121 ttcataatct tctaaccatt cttggatttg cccattacta cctatttttg ttttaggtag
     9181 tttctttttt aactccttca cacgactaat aaaatccgaa ttgtctccta attgttttgc
     9241 aatgccaatg catgaatcac aaaaatatct tagaatttga ttatcaattg tagatgatag
     9301 acaagcattt ccttcaatac cattttttaa gcgatattta ttttccggtg agacacttgg
     9361 acctgtcatc aagtagccat ccacctcaaa taaataatct tcaaagaaaa gaaatgcttc
     9421 ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct tggaaatata aatagtgttc
     9481 ccaaatatga gtacataacc atggaatagt taatacccaa attgcagccc ccatggcatg
     9541 agattgggga gccgtatcgc caaaaccatc cgtattatga tgtgctgtaa aacctctagc
     9601 tccatacatt ttcttagcgg ttagtcttcc cggttctctc attctttcga gcatatcaaa
     9661 taatggatat tctacttctg gtaaatcaca tggacctacc atccaataat tcatttgagt
     9721 attaatatta atcgtatatt tagaacccca aattggattt aattcatcac accatattcc
     9781 ttgaagattg gcaggtaaac cattcggttg actagacgat attaacagat atcttccata
     9841 atgaaataac aagttagtca agtagttact atacttttta gtgttttcaa gaagtagatt
     9901 cgttggaatg ctaagacaat ctttactata gtctagttta aaatcaactc tattaaattg
     9961 ctcctgatat ttttttacat gttcatcttt ttctgtaaag taatcaatac tactaaattc
    10021 tccctgaaga gaagaaatat ctatatttcc ccaataatcc gtcattgatt tgagataaag
    10081 aaatacctct gtagcattcc gaataactat tgtctctccc aatacactta cttcaccatc
    10141 cgtaacctta gaatgacata ctactttaaa ctgaacacct tttctacctc cagcagaggc
    10201 cgacattaaa attgtacttg aatccagttt agatacttcg tcattaaacc gtttatttct
    10261 acccaaatta atgtttaaat ttaatgtgtt ttgaactgat gacactatac ggcaacataa
    10321 aatattctta ttaaaactcg taaaatattc tctttttatt tgtaaattac aactattagg
    10381 ctcaaacaca acattagaaa tagctgtatc taaatctagc tctctttcat acaatgaaag
    10441 agcacaagac tgaatatcta tatgctcaat gtaaagttcc ccaagtaatt catagtggct
    10501 ttgatctctt ggggtagcaa acattgttaa ctttatcaat tcttcggctt tctgaatttc
    10561 tccatctaaa agatattccc gaattttttt aagatgcaat agtgagtctg gattatttct
    10621 atctgacttt cctctatacc aaatagtctc atcgtttagt tgaatacatt cttttgtagc
    10681 tgaaccataa atcataccac ctaaatgacc gttcccaatc ggcaaggctt cattccaatt
    10741 tgaggcagct ttcttatacc ataatttcac tctttacctc tcttccaaaa tggaggtgat
    10801 atcccaaata ccacctccac actttctact acttcaaaat tcctaaaaca actaggataa
    10861 ctccaatagc cataacacta aagattagta caaccggatt ctttcctttt ctaattaatt
    10921 tacacattaa taaagtcaaa gccataggga taaatcctgg aattaatttt gtaatcattt
    10981 cttgaacaga aataacaagt tccccctgct taaattctaa tccaaaatta ataccaacca
    11041 ttgatggaat caaaccaccc actagtacta gccctaatgc tgtcgccata ctcgtaacgc
    11101 gattcaatgt tccttttgta ttattttctt ggataagact agaaccctta gtatacccat
    11161 atttcaaacc gaaatattta acaggaatat taataatatt aaacaatatt aaggcgataa
    11221 agatacctaa agcaccgccg tctttagaat aagacgcacc aatactaaaa cagataggaa
    11281 ctagtgtcag ccagaacaaa ctatctccta gaccagccag tggccccatc aagccaactt
    11341 taataccagt aattgaagct gcaccttcat ttccttcttg ttcttccata gcggaagtaa
    11401 ctccaagaat aaatggtgcc gctgtttgat gagtattgaa aaactcaagg tgacgtttca
    11461 ttgcaggaga agctgaatct ttgtctgggt atagtttttt caatactgga agaattgtat
    11521 atagaaaacc taggttctgc attctctcat agttccatga agaaccatac ataaaacttc
    11581 gtttgaaaac ttttttaagt tcaactttag ttactttatt attcatcata gatcaagatc
    11641 ctcctcaaca tcactacttg aagttgtttc ttgtggttta cttccaatca tatcgtagaa
    11701 gtatgctacc gcaataccaa ctagtgagat cccaatggtt gacattcctc catacacaga
    11761 acaaatgaat ccaatcaaca agaataccca catatttttc ttgagcatca tatttaaaag
    11821 cataccaaaa ccaattgaag gtagtaaagc acctgcagag ttaagtccct gcataacgat
    11881 tggtggaacc ttagcaaaca agtctgccac atattcccct ccaagcataa tagctaggaa
    11941 aattggtaca attttaaata acgtgattaa aaccaaactt gaataatgat aaaaaccgat
    12001 ctttgaataa tctccgtttt tagcatcatt atcagctttt ttcacaaaat aaacatctaa
    12061 agtttttgca agaacatcca actgttgggt agcaactgca attggaactg ctatagcgat
    12121 accagcagtt tctccttgac cagataaaat accaaatgca gtaccaataa tcgcacctga
    12181 aatagtatct ggtggagtgt aacctccaat acctgttaca ccgagccaag ttaattcaag
    12241 agctgaacca ataagaacac cttgggtgaa atctcctaag actaagccaa ccattgcact
    12301 tgtaactaac ggacggtgaa tcataaataa cggtccatta tagtcaatag tggcaataat
    12361 cccaactaat gtcaccagta atgcttgtgt gaatagcata tactgtacct ccttaaatta
    12421 tttttataaa aatttttcca acattgtaac tttatcatta ggaaccattt gaatttcaac
    12481 tctcgttccc ttatcaacta ttttcttaaa ataatatttg tcttcttcac ctagagctac
    12541 acctcccgtt accttttcat tttcctccgt tttactcatc tgtcctacat tgaggtactc
    12601 caattttaaa tttccttcaa tagaatcata cacatctttt ggatttgtat atatcagcat
    12661 tgttctcttt tttattggca cagagtttaa aacttccaca aaccgtttta cactaaagaa
    12721 aacaattttt aaacctaccg gtgcagaaat ctttaaaata gattgtcgtg ttttatcttc
    12781 tgagatgcga tcattaacaa tgataacttg ctcaatatca tactttttta gccacgtagt
    12841 gacaacttga ccatgtacca gacggtcatc aatacgaaca aactctatag acataaatcc
    12901 tcttcctcct ctacgttaag ttgttgttta acattaaaca aactattttg agcattttga
    12961 acaatttctt ctaaattgat ttttgaatca taacttgata ttaattccac taggagaggg
    13021 atattaaacc ctgttacaat atcaactgaa tccaaattta aaaaccgtga caaagccaca
    13081 ttattaggac ttcctccaat caagtcagtc aaaacgataa cctcttgatt tgagtctaac
    13141 agttcatcca cttgattttt aaaataatgt tcaaactcta caatattctc tccaggcatc
    13201 aaacctaatg tcctaactct atcatttgtt gtctcaccaa caaacatttc tgcggtcatg
    13261 agagctccgc tagcaaaatt accatgactg gcaactaaaa ttcctctatt aaacattttc
    13321 tctttcaaca actactcctt tcttaaggat aatattagca taaagtgaag tttctcctgt
    13381 agcaacaata gcataagctt tcttactacg ttcataaaag tcttctcttc taagataagt
    13441 aatcgtttta agatctgtac catgaccttc aatcatctgt ctataggtac cccatatctt
    13501 aggaatatca tcacccgaaa caacgttcat aaactgaatt gaactatcga cgtaactatc
    13561 taatggcatt aaatacagaa tggaatctaa taattctgga atatttacgc catcacaacg
    13621 aattagctta tttgcacatg aggcagaagg ataattcgcg tcagctaata ctatttcatc
    13681 tccatgtccc atttccatta aagtcttcaa taaatctgga gaaatatttt tcggtatatg
    13741 ttttaacatt aatatcctcc ctattttctc tgaccgtatg ttttaaattt ttctgccatt
    13801 aaatccatct cctcatcagg aagaactact ggctctccaa aattcttagc taaacaataa
    13861 atttttgcac aatattcaac ttcttcaaca atattaaatg cattcaataa attttgtgca
    13921 cctgctaaaa ttccatgatt cgctagtaaa actgctctac gaccttccat tgctttagct
    13981 gcattcacag ccaattcttt cgtaccatat gttgcatact cagctacccg aacatctttc
    14041 cctgccactg caatcatata atgactagcc ggaagtggtt ctctgagaca agctaatact
    14101 gttgcataag ttgtatgagc atggataatt gcatcgatat catcacgagt ttgatattga
    14161 atcaaatgca tataccattc gctagatggc aagcgttctc cctctacaac atttccatta
    14221 atatccatca ctacaatatc ggattctttg atttcaaaga aatcaatacc cgacggggta
    14281 attgccatca attgtttttc acgatcgaaa acactgagat tcccacctgt tcctttcgtc
    14341 aaatctgttt ctactagctt cttgccatac ttaattaatt cttgttttac atctgacatt
    14401 cttgtcctcc tcatatcaaa acactaaata tttttcaatt caccaattat ccccccttct
    14461 tgtacaaaac ttaggaaggg ggagggaggc aaatttacaa actctcaatc tttttaattc
    14521 ttttgggagt aataactctc taattgtaga aactcctcaa taacatggtg agcttcttcc
    14581 atccctttta attgtcccat agctatgagc tgcacaacaa tattccccac agctgtaccc
    14641 tcagtcgaac ctgtaagaac ctctttacca gttctatcag caatcatttg gttaaagtaa
    14701 ctggctctag cacctcctcc aatcacatat atcctcttat aaaccttatg agttagttct
    14761 tctagtaact ctatcgcttt cctatacgtt tcagctaggc tttcataaac aatcttaaat
    14821 agttgtccat ctgtccactc tctagtttca tgatgataag ctagatattc tgtcaaagtc
    14881 ttgtgcatat cagattctgt tgcaaattca gttgattcag tatcaatcag aggaagattt
    14941 tctttttctt tctccaccat tgtcctaata tcatcaaaag aataggcttt ccctcttcgt
    15001 tcaaatgaac gtcttagttc ctctatgatc cacaaccctg tacaattctt cagaaatgta
    15061 atcactccat ctttaccgac ttcatttgta aatccataac tgaaggattc ggtagtaaga
    15121 atcggtgaag taagttccac tccaaccaaa gaccaagtac ctgatgaaat aaataaacta
    15181 ccttctgtct taggtactga gacaatcgca cttgctgtat catgactaca aacattcaca
    15241 acaggaatat cgcctaaacc atactccttt tttatccttc caagaacatt tccctctgaa
    15301 acaatttcag gaagtaaaga tgaatccaat tcaaatagtt ttaagatatt ctgattccaa
    15361 ttttgactcc taggatcaaa taattgagtt gttgaagcaa tgcttttttc tgtagcaaac
    15421 ttacctgtca agagataatt aaacaaatct ggcattaaaa gaatcttatt ggtcttatag
    15481 aaagagtcag gagattcttg acgtgcctta aagagttgaa acaaggtatt tatctccata
    15541 atctgatttc ctgtctctga atacagtttt tctaattcag tcatttcaga tatttccttt
    15601 aacactccct ttgttctttc atcacgataa tgaacaggtt gtgataacag cttaccttca
    15661 ttatcaatca gtccaaaatc aactccccat gtgtcaatac cgatagataa aatcttgtaa
    15721 ctagtattag ccaagcggat actttcaaga attttagcta gtagaaagtc aatatcccaa
    15781 gataaatgcc cttttactct aataggtaga ttagaaaagc gatttatttc ttccattact
    15841 agtttatttt cagaaaggta accaacgatt gctcttccag aagtcgcacc taaatctatt
    15901 gctaaaaccg cttccatttt tcttctctct tcgtccttga ttaagtttat tataatcccc
    15961 acattttatt ttttcaatat gtgaacgctt acttggataa tgttcaaatg ttaacccaat
    16021 attcataaaa ataattcaaa ttcctccaat ttgtgctata atatagttga aatgataaat
    16081 taggaggagc ttatgataaa agatgaacgt gtacttgaat tgattgaaat tattaaaaag
    16141 aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt tctccagcac aagtacctta
    16201 cgtcgtgatt taattttctt agaaaatcaa ggtcttatca aaagaaagca cggatacgtg
    16261 accctgtcct ctatgaacac aattgaactt tctcatcaaa tacgggaagg agaaagtact
    16321 aggcaaaaaa gactaatcgc tagtctcgct aaagacttta ttcggtcagg tatgtgtgtt
    16381 tatctggatt ccagtacgac tgtctacgaa ctttgtccct atctttctga acttgataat
    16441 ttgattattt ttacaaatgg tttacatact gcacaaaccc tatctgaaac tgttaaagat
    16501 agctccaaaa tctttatcac atctggcgag gtcaaacatc aatcctgttc cgtggtcaat
    16561 tacgataagg aaaattcttt attagatcat tttaatatcg atttagcatt ttgttcagca
    16621 agaggtattg atgaccaata tgtttatgaa gcttctctca gccaagctat ttcaaaaaag
    16681 aatattattg acaaagccca tgaaaccatc ttactgattg atagctctaa attttacaag
    16741 actggatttt ttaaaattaa tcccctatcc aaatacacaa cctttatttc tgacaccgtg
    16801 ccagatcaaa aattattaga cgcagtcgaa ttatttgatg gagaatgggt ttctgatatt
    16861 caatgaaaat caaataggaa gctagtctca gcttgctcaa agtacagatt tgaaaactga
    16921 tgaagtcaag tcccccatgg acacggcaag acgaagctga catgatgtga agagattttc
    16981 gaagaatact cgttctgtct gctgactgat ttacaaatat tcaccacatg acattatttt
    17041 cttagcaacc ctaaaaacag aggctggaca aaaactcaat ttcaagagaa atggggcaaa
    17101 tattcccaca ataaaacgca tagtatcaag tttttgcaca cctgatatta tgcgtttttc
    17161 tgattttaaa gactttgtcg cctagaccct atatttcaag aattaagtga ccttgatgat
    17221 ctaaatgtat tgtggtatac tatttttgtc atcggttacc gattacgttc ctatgggttc
    17281 gtgagaggag gtgaaactaa tgagccttat catagagctc gctcttacta ttatagcgga
    17341 tgttatagct ggaattatct tgtatttcat ctgcagatgg ctagatagta aggagtagac
    17401 cgaatgacta gcctataaac acccgttaaa tctctaagat acgtcaaaaa agcccttaac
    17461 tacggccata gttaggggct ttggtgttct aatgaacctt atcaattaac tacattttag
    17521 catataatct acaatagttc aagcattaag tgaggttgat gatctaaatt tagtgtggta
    17581 tactattttt gtcatcggtt accgattacg ttcctatggg ttcgtgagag gaggtgaaac
    17641 taatgagcct tataccagag cttgctctta ctattatagc agatgttata gctggaatta
    17701 tcttgtattt cgtctgcaaa tggctagatg gtaagaagta gaccgactga ctagcctata
    17761 aacacccgtt aaatcactaa gatacgtcaa aaaagccctt aactatggca ctagttaggg
    17821 gctttggtgt tctaatgaac cttatacact aactacattc tagcatataa gtcctaatat
    17881 ttcaagagtt ttatttattt tttcaggttc ccttagttct gaaaggtcta taatgaagtt
    17941 agccatctag tatcaaaaaa ccgactagct cttatgaact agtcgatttc tcatcaatgc
    18001 gccaacattt cttgggcgat ttcttggcca gataggttat ctgggtagta ggttggccag
    18061 ttgtccattt cttcaaagag ggcttcttgg cttgtgcctc caaagaagat atggaaatgt
    18121 tctgccttaa ctggggcgat attgtggtca ctaaactgaa catacttgaa ttgtccagcg
    18181 tcagcatctg tggcttcaaa gaggaaacgc acgccacgat tgcctttctt gtaagtcaaa
    18241 attttcttac cgacatactt gtaagtgtat ttcttgcttt gtccaccttg aacaaattcc
    18301 atagtattat cagtaatgtt aatcttagtc acatctgtct gatagccttt tgtatagtaa
    18361 gccttgtact cagcctgggt catcttacca gtcaacttag ccttgtagtc aaagacttgg
    18421 tcaaacgtgc cgtcttcaag gaaaggataa actgattgcc agttacctgc atagtcactc
    18481 aaggtgcggt ccttgacagc tgcatcctcg aagtaaccat tttggactgt cttggtatcc
    18541 tctgcctttt caggctcgat tgctgggcct tcttggtctg ttgtttgttt caaagccttg
    18601 aggtttttct ccatgataga gatgtaattt tctccagcct tggtgtcctc ttctgtcaga
    18661 ctttctaaag gattgaggac atcagttttg acacctgctt cttttgaaag tgtgttagca
    18721 agggcttgtg aggcattttc ttcaaaatag atataggcga ttttattttt cttgacatac
    18781 tctgtcaatt ctgccaagcg agcagctgat ggctctgcat ctggagaaag tcctgagatt
    18841 gcgacttgtt tgagtccata gtccaaggca agatagttaa aggctgcgtg ttgagtcaca
    18901 aagctctttt gttttgcttg agacaagcct tctacgtaag ccttatccaa ggcttgcaat
    18961 ttttcgatat aggcagctgc attcttctca aaggtctctt ttttatcagg ataatctgct
    19021 gacaagctgt cgcggatgtg ctctactagt ttaatggcac gaactggtga taaccaaaca
    19081 tgggggtcaa actcatggtg atgaccttct tctccatggt catggtcccc ctcttcttcc
    19141 tcgccacctg gcaagagcaa catatcgcct gtcgccttga tggttttcac ttttttctta
    19201 tccaaggtat ctagcaattt aggtacccat gtttccatgt tttcattttc ataaacgaag
    19261 gtatctgcat cttggatttt ggtaactgcc ttggcagatg gttcgtattc atgaggttct
    19321 gtcccagcac cgattaggag ttctacatta gccgtatctc ctgcgacttg cttggtaaat
    19381 tcatagacag ggtaaaaggt tgtcacgata ttgagtttac catctgcctg tttttgattg
    19441 gaacaagcca ctaaaaacaa ggcacataga ctggctagta ataagctaat ttttttcacg
    19501 ttcgtctcct atttgataaa acgtcttact aaactgatta gtataaagac agttacaaaa
    19561 ataatggtaa tacttgcact tgcaggtgtt tctgcatagt aggaaatgta aagtcctgct
    19621 accattccca aaaagccaat cgcactggca agcagcataa ccgatttaaa gtttttcccc
    19681 agacgcaggg caatactagc tggcaagacc ataatggtcg ataccagaag agctcctgct
    19741 gcaggaatca taagggcaat agccacccct gtcaccatgt taaaaagaat ggacatggta
    19801 cgaactggca agccatccac aaaggccgta tcttcatcaa aagttaagat atacatagga
    19861 cgaagaaaga gaaaggtcaa aatcaaaaca accgccgcaa tgacaaagag ggaaatgacc
    19921 tgttcttcac tgatagtcac gatcgaacca aagagatatt ggtccaaact cattgaactc
    19981 gagcttttac ccttgctcat gacaatcaga gaaacagcca gacctgttga catgaggata
    20041 gctgtcccga tttccataaa gctcttgtaa accgtacgga gatactccag aaagaccgcc
    20101 gcaatcaaga caatggcaat agtagaaaca gttggagaaa tccccaaaac cagaccaaag
    20161 gctacacctg aaagtgagac gtggctaagg gtatcactca tcaaactctg acgacgcaag
    20221 atgaggaagg ttcccaatac cggtgagaaa agactcatag caataaccgc caaaaaggcg
    20281 cgttgtataa agtcgtaaga taataaacta agcatggctc acctcctggc cattctcatg
    20341 aacgttgaaa caacgccatg gcgagtcttg gttacggact agatgaatat tgcgatccgc
    20401 ataatcctta acttcttcag ggtcatgggt aatcatcaaa acagccttgc catgatgatg
    20461 ggcgctgtgg tgcatgagtt cgtaaaattc atttttactt cctgcatcca tccccgttgt
    20521 cggctcgtct aggataaaca catcagggtc agaagcaaac atacgcgcaa ttaccgctcg
    20581 ctgcttttgt cccccagata gagaccccaa gcgtttgtct cgatgttccc acatgccaac
    20641 tgagtccaga ctggccttga tatgctcctc atcatgagca ttcaaacgac ggaaccagcc
    20701 ttttctcgga tagcgacccg acttgacaaa ttcatagacc gtacttggaa aaccagcatt
    20761 aaaactggca atttgttgag gaagataggc tattctcaat ttcttacctt gcgtatttgt
    20821 ctttgaaata gccacctttc caatgcgtgg ttgcagaatt ccaagactgg ccttgatgag
    20881 cgtcgtctta gccgctccat tttccccagt caaggtaaca aattccccac tatcaacact
    20941 ataattgata tgttcaagaa caggctcctt atcataatag aaggacaaat cctctaccgt
    21001 aatatatctc attatttgat ttctcctact aaagcagtca aaaaccgctg aatcactttt
    21061 tgttcatttg gagtaaactg agtcgccact tgttcatagg ttaaaagtgt atgctcatgg
    21121 tgatggtggt gctcctcagc gattggacga gccaagtcag tcaactgata aaaaatcaca
    21181 cgcgcatctt tagaatcttt agatgtttcc aacatccctt ccttgaccaa agacttaatg
    21241 gccttggtaa ctgccgcctg actgacattg agacgacggg ccaattctga atttgttaaa
    21301 gattcctctg acaagagcat aaggatatgc tcctgagtat tggtcagggc cacctcgcta
    21361 gtgcaatgac ctattaggat ttcatgctga ttttccgcct gcaaaatcac ctcattcaaa
    21421 aaagcattga tatcctttgc tagctgtctc atatctgact cctttccttt tagacttctc
    21481 ttttttaaga gaaaaatact attctttgac attttgttta ccagttaatt atatcacaag
    21541 caaaaaaaga gtcaagaaaa aacgtgaaaa ctagtttcat tcttgaactc ttctatatta
    21601 tattatctat tgaaattctt tgacatctcc atcataagtc gcccaatctt tgctgaaaaa
    21661 gcgctcattc agatggtaag tcggagctgg tgtgggattg gataggaaag gatcaactgc
    21721 cttgtcaaaa gccaaccaac ccaaccaacc aaggtgaatg gtgtccttca taaagaaagg
    21781 ctccccaccg tccttagaaa aatctgctat attggtaaaa ccttgacttt ctaactggta
    21841 gcgaatcttc tgcaccgttt gttggtacat atcctctcgt agaccagcat agtccatcca
    21901 ttttttatta acaggtggaa tgataaaaat cgggtttacc ttagatttag aaaactgtgt
    21961 taaaaccaac tgcaagtcat tatactctgg cgacttgaga taggtaaagc ttttctgaga
    22021 atcctttaat ttcttcaaat ccttcttgat ctgctcatta tagaaataat tttccattcc
    22081 catctcatta ttggaagtat ttttttcagc atctgctttg acaacatctt ctattgcttg
    22141 ataagaaaac tggtctggca agatttttaa atacttagct acatgcttat cgtagttaac
    22201 atagcctcta accgaaaact gaccaaaaaa ggaggcttgg cgttcattaa aacgagccaa
    22261 taattcaatc atttcattgt ctgctgtcga caattctcct ttacttgcca acttctgaac
    22321 caggtccttc atagctacgt ttgggaactg ttgcagtaag cgagtcgctg catattgact
    22381 agcctgatcc ccagattgat gtttcagaaa actagtcaac tggtctccat taaaatactg
    22441 ctggaaggct gctggatcat agccattttt actgaaccac tgaggtgaga taacatacac
    22501 aacttgttta ttctccagct gtggtaacat ctgttgcatt ccaaaatatt ggttaagcga
    22561 tgcagctccc ccctgtccta aaagataagg acggtaggaa cgattgtatt tctcagctaa
    22621 taccgcagga tgagcaccgt caaaacgaag ccattcacta gagccaaaga agggaacaaa
    22681 acgcacattt ggatcagata gtgctctgac tttttgactt cgctccttaa aactatcgat
    22741 agtagtagcc actgctgaac gcttttcagc tcctagatta tgatgcatct cagtaggata
    22801 aaagaaaatg agcagaaaaa ccaacaaacc agcgatcaag accggtccga agatcatcca
    22861 taagcgttta agcattttgt agctccacaa taccagctat gattttatta gctgtattcc
    22921 agtcgtcacg accaaactct gttacaggga cacgaatgtc aaaacggttc tcaatctcca
    22981 caatcaactc aaccgttccc atactatcca agacacctgc atcaaaaaga tcttcatcca
    23041 tcatgtcaga aacatcttcc ataaacaact catcaataat ttcaataact tctgatttga
    23101 tatccatatt ttatttcctt ttatttttta aaccatagat tattcaagaa tccagaaaag
    23161 attaagaatg acaacatgac aacatggaaa gtgacaacca tgccaagcaa ctgaatccag
    23221 cgattctcag gtagggcagc cttccctgct tttttccgtt ccttattgag cgtttttttc
    23281 ttgcgaaccc aggcatcatt gatgaccaag cctagtccat gaaagagtcc ataggcgata
    23341 tagtaccagg tcacaccatg ccaaaatccc ataatcagca tatttacaat gtaggccatg
    23401 cttgaggtta cattacgatt tttaaagact ttctttctgg ttaacaccat caccattcgc
    23461 ataaagacaa agtcacggaa ccagaaggac agactcatat gccagcgatt ccaaaactcc
    23521 tttaaatccc ttgataaaaa gggcttgtta aagttgatag ggctacggat tcccatcaag
    23581 tttgagatgg ccaaagcaaa catagaataa cctgcaaagt caaagaagag ctccagacca
    23641 aaagtataca taactgccaa ggcatagaga ttaaagaagc cacctgactg caaggctaaa
    23701 ttcttcagag gaggtagtaa ggtctctcct aaaacatgag ctaggataaa cttatacaaa
    23761 aagccccaca tgatatagcg gacagattca tccagcatat ccatcaactc atctcgctca
    23821 ggaatagcct gataattttc attaaatcgc ttaaagcgat cgattggacc actcgagaaa
    23881 gttggcatga agagaaggaa acggaggaat tcccagaggg taaaatcctt aatcactcca
    23941 tctctcagct cgatgataat cccaaccgaa cgaaaggtca ggtaagaaat tcccaagaac
    24001 ccaagcaaag actgcgttcc attgatagct ggttgcacct tgacaaagat aatcggaagt
    24061 agggacagaa aactaactaa gtagaagacc cacttgccat ccttgctttt tcgataatgc
    24121 ttgtagaaaa gcaggagcaa tatttcccag caaaggtaaa tacccaaggc agctagttga
    24181 ttggtctttc cacccaccaa catggtgaca ataaagaaga gacttaccaa cacttcatac
    24241 caggcaaagc gtttcttgaa aaagaggcct ataaagatgg gcaaggttgc agcaatcaca
    24301 taaacaaaat actgaggatt gccatatggc tctaaatgag gaagctgttg aaaaaactcc
    24361 atcatctctt attcacctcg ttaatcaatc ctttgatgtc aatctttcca tttggagtca
    24421 gtggcaaact gtctcggtaa aggaatttag atggcatcat gtaggacatc atgatgtctg
    24481 tcaggtcttc cttgatggcc ttggtaatat cgatatctcg ctcaaactgc tcacgaacac
    24541 tgtcttttaa gatgacataa gccaatagat tttgtacctt gtggtccttg ttatagcgcg
    24601 gtactgcgac agcagattcg ataaagcgag acttgttgag gttttgagag acatcttcta
    24661 actcaatgcg gtaaccgttg aacttaatct ggaagtccat gcgtccgccg tagagaagca
    24721 agccctcatc tgttatggtt cccacatcgc ctgtgtgata ggctggcaga ccttcaaact
    24781 caaagaaggc ttctgctgtt ttttcaggat tgttcatata accttttgaa acagctggcc
    24841 cagaaacaat gatttctccc tgttcgccat ttggcagttt atttccttcc tcgtcaatga
    24901 taaaggttgg agaatcagcc ttggtatagc cgattggtag gcgtttgaga gtcgctaaca
    24961 tctcgtctgt cacggcaact gctgacagag ctactgtcgc ttctgttggg ccgtaagcat
    25021 tgatgatacg ggcatttggg aaacgctcgc gcagtttttg agctgttttg accgtcaatt
    25081 cttcaccatc aaagtagaaa tgcgtgattc caggcatttt ttcactgttg aagtattcag
    25141 acaacatggc catatctgca aaggatggtg ttgatgtcca gatagcgatt ggcaatgaaa
    25201 agatagccgc aaagagttgc ttaaagtcct gagtgatgac tgaaggaaga gtgaaaagcg
    25261 taccaccaag tgccaaggtc ggtgcccaat acatgacaga caagtcaaaa gaataaggtg
    25321 gctgtgccag catttgcgga cgactcggtg tcgcaaattc cttatccgta atcatccagt
    25381 ttgtaaagct gaggagatta tcatgtgaaa tctgcactcc cttaggctta ccagtcgtac
    25441 cagaagtaaa gataatgtag taattatcat ctcccttgac tggatgcgtg atttcatagt
    25501 tgttcccttg ggcaaaggct tcttgaacct gagctagatt tatcattggt gtagaaacct
    25561 gctccaaggg aaaggctgaa atggcaataa tcaagcttgg ctctgctact tctaaaatag
    25621 ctgaaactcg ctccaaggcc gaatggctat caattggaat gtaggcatga cctgacttag
    25681 tcagcgctac aaaggttgcc aacatttcat attcttggcc accaaaaaca accacaggag
    25741 acttctcagg caagcctagt tggtcaatga ctgcagccaa actatccgaa tcagacttta
    25801 aatcgccata agtgtgttcc tgccccaaaa cattatagac aggatagcta ggctgtgtct
    25861 gagcaaaatg ctcaatggtt tcaatcatat ctgctattgg tttatttgac acaataggga
    25921 ttctccttca agttaaaatt cattatagat aaagcttcct tgaccctgac caagatagct
    25981 aaagaagtaa agcagcccta gaaagataag aaaatacaag gctgtccgac caagaaagag
    26041 gtacaattct tttctctgtt tcatcaagaa aaaccattca tttctgtaat ttttcgctaa
    26101 aataagagtg attcttacta gcttattttt ctaccattgt accactttat atagtatctt
    26161 ttcaattgtt taccgtatgt ttccaataga tttcagctta ttttaaggat tatgcggttt
    26221 ttctatatct atttcaaaag aaaaaagcct gagattttca tctcaagctc tagcaataat
    26281 agttattttc taaactaaaa aagtgagaat acaagcacgg ccaaggctgc accgataaca
    26341 ggtcccacaa caggaatcca agcataagac cagtctccgt ctcccttgtt tgaaattgga
    26401 aggatactgt gcatgatacg aggtccaagg tcacgcgcag gattcaaggc ataacctgtt
    26461 gtcccaccta gcgatagacc gataccgaca atcaaggtac ccactgcaaa ggttccgata
    26521 cctgcctgaa aatcgtaaag acccaaagca aagattgtca acaccaaaac aaaggttcca
    26581 aggatttcgc taatcaagtt tgatacagta tccttgatgg ctggtccagt actgaaggtt
    26641 gccaggatat tgcctgcatt ttcttctgcc tcatagtgag gtttgaattg caaccaaacc
    26701 aaaatctgac ccagcatagc ccctgcgaac tgggctaaga tataaggcaa aacggaagcc
    26761 caaggcaagt caccttttaa agctacacca attgtcacag ctggatttaa atgagctgga
    26821 ctgagcttgc cagatacaaa tactgcaacc gcaactgcaa tcccccaacc catagtaatc
    26881 acaatccaac ctgagctatt gctcttggtt ttaggaagaa ccacacctgc aacaacacca
    26941 tttcctagaa gaatcaggat taaagtccct agaaattctc caaataattc attcatcatc
    27001 tttctgtctc cattaaaaag aagggacgag cgacaaggaa tgctgccctc cacctctttt
    27061 attttttctt aattttttaa ttctgctaaa tcgttgttag cgagagctgc ttcgacatca
    27121 gcacggtaag ttgctttttc ttcttctgtc cagtcataga atcgtcccat ttcatccaaa
    27181 actggctcaa cgatgctatc caagctatca cgcataaaga gcatatggtt ggtacgacga
    27241 agaaggaagt caactgggct aagagccaac tcgttgcgca ttgcatagtg aagggacaaa
    27301 gtatctgcca agctgagtcc tggcgcttgt tccaagctgt gagcaagtgc aaagactttc
    27361 ggtgcatttg aaccgtaaag atttgccaga tagtgagctt ccttgctatc caaaccacgt
    27421 gatactccaa gttgcgcaaa ggcttcgatt tctgaatcca catttgctgg gttcaattct
    27481 ccacctgaaa cagggtaagt tttagaattg atcaatttaa agctacggtc aaattctgct
    27541 ttgaggatgt caaccacgcg ctccatagct ccttcagcca tcttacggta gtctgtgatt
    27601 ttaccgccag caagagtcaa aagaccattg tcatcacggt ccaagctaga cccacgagaa
    27661 actgcagatg gatccaaata tttctcagat gtgctacttt caagcttgct gacagcagac
    27721 tcaacatctt cacgtgtttt ttctttggag agataagatt caacagtcgc aatcaagttg
    27781 tcaaagcttt catcactgat ggtaccgtta tttccaccat tatagtcaga ggcactgttc
    27841 cctgcaatca atggacgaag acctgcccag ctgctttcga tatcatcaat ggtgatgttg
    27901 gattctggaa agcggttgtt gacaatgcca agtagataat ctacatcttc ttgagttact
    27961 tttggatgct ccaaatcacc tgtgtagtct gtatcagttg taccaaagta agtcttgttt
    28021 tcacgtggga gaacaaagac catacgaccg tcacccaaac ctgtgtcgaa gtaaactggc
    28081 tgtgaaacct tgattttgct tgaatccact accaagtgaa ctcccttagt tgggcgcatt
    28141 tgtgagaatt gcgttccctt attagacaaa ttacgtactt tatcactcca aggacctgtt
    28201 gtattaataa ccagacgggc cttgatttca aatacttggt ctgtcaagag atcacgagct
    28261 acaacacctg taatcttgcc actttcgtca aagaggaagc cttctgcctt cacgtggttg
    28321 gcaatgaggg caccgtcttg gttggcacgt ttgatgtttt caatcacgag acgcgcatcg
    28381 ttgttacgga agtcaagata cactccacct cctaccaagc cttccttctt caagtttggc
    28441 tggcgttcca agacttgatc cttgctcaaa accttgttcg cagctgacgt gttgctcaca
    28501 cctgctaaaa ggtcgtacaa gtccatggct actttaagac ggaagaggct aaaggttgct
    28561 ccatcttcat cgtaaactgg taagagcatt ggatctgatt ttggaatgtg tggagcgatt
    28621 tgttgaacca ctgcacgttc agaaaccgta tctgagacca cttctacgtc aaattgtttg
    28681 aggtaacgaa gtcctccgtg aaccaatttt gttgaacgac tagatgttcc ttctgcaaag
    28741 tcttgcattt caatcaaacc agtctcaaga ccgctagctg ccgcctgcaa ggctacacca
    28801 gctcctgtga ttcctccacc gataatcaag aggtccaggg tacgttcctg cattttttta
    28861 attgacaatt cacgtgtttt ctttgaaaat tccatattta cacactttct aaataaatcg
    28921 ctttattctg ccagtattag tcgtctactt ccgcaaagac ttgagttgct ttcacagcct
    28981 tcttccagcc cttgtagagt tgttccttgc gagattcgtt catagatggc tcaaagagtt
    29041 ctcctgtctc gttcaagagt ttcaactcgt ccaagtcttt ccagtaccct actgacaaac
    29101 ctgctaggaa ggccgctcct agagctgttg tttccaggtt tttagcacgt gcaatgtcaa
    29161 tgcctaaaat atccgcctgg aactgcatga ggaagttgtt catggctgca ccaccatcca
    29221 ccttcagtac ttgaatggcg gtctgagtat ccacttgcat ggtgtcgatg atatcacgca
    29281 cttgataagc aatagattgc aaagtcgcct tgataaagtc ttctttgctt gttccacgag
    29341 tcaaaccaaa gacggaacca cgagcatttt ggttccagta tggagcgcct agacctgtaa
    29401 aggctggaac gacataaact tcatcgttgt tgtgagaatc acgagcgtat ttttcagatt
    29461 ctggtgaatt ttcaaccatg cgaagaccgt cacgaagcca ctgaatagca cttcctgcga
    29521 tgaagataga accttccaag gcataataaa ccttaccgtt gattccgtaa ccaatggttg
    29581 tcaagaggtt gttttcagac aactgcatct cttccccagt attcatgatg atgaaagagc
    29641 ctgttccata agtattctta accatacctg gctcaaaagc caactgtcca aagagggctg
    29701 cttgttggtc cccagccata cctgagattg gcacctctcc accgtagaaa tggaatggag
    29761 ctgtcttgcc gtagatttcg gagttagaac gaacttctgg aagtatagcc ttcggaatgt
    29821 taaggatttc caaaatctca tcatcccatt tgagttcttt aatgttataa agcatggtac
    29881 gagctgcatt tgagtagtca gtcacgtgag ccgcaccgtc agtcaatttc caaaccaacc
    29941 aagtatcgat agtaccaaag agcaattccc ctttttctgc tcgctcttga gcaccttcta
    30001 catgatccaa aatccaacga accttggtag cagagaagta agcatcaata atcaaaccag
    30061 tcttttcatg gaatttttcc acataacctt ggctttttag ttgctcagcc aaaggtgctg
    30121 tctggcgtga ctgccaaacg atagcattgt agataggaag tcctgttttc ttatcccaga
    30181 caaccgttgt ttcacgttgg ttggtaatcc cgattgcctc gatttgattt ggcttgacac
    30241 cactttcgat gaaagcaccc gcaataactg actgaacaga gttccaaatt tcattggcat
    30301 tgtgctcaac ccaacctgcc tgagggaaaa tctgggtaaa ctctttttga ctcgagctaa
    30361 ccttttcccc ttttttgttg aaaatgatgg cacgagaact tgtagttccc tggtcaatgg
    30421 ccatgatgta tttttcttgt gacatgtact gtcctcctga taaagatctt gaggtgtttc
    30481 ctctttacac ttactagtat acaaaataaa gcgctttctt gtttatcaac tttttttaat
    30541 ttttaaaaaa atgtgaggag attgtgtgaa tttcacaaaa aagacctgga ttaaccaagc
    30601 cttttaagtg aataataact ggcgaatcgc taccaaatcc tccatatcca agtcattttt
    30661 taaataatag actggtgtct gttccttctt atgaatcggg ttattggtaa ccagcaaatc
    30721 ataatgccga ctagggtcat aagcttcaat ggtaataaaa cgattgtatt ccaaataccg
    30781 tttcaaaatg gctgccatcc ttgaaaagac aagaaaacca gatgtcaaat ccagaccaat
    30841 ccgcatatgc tggccaccgt tttcagccat atattcgatt aactggagcc attcccagag
    30901 aatcttctta tctaaatctg tcccctgttg aaaagtaggt agagcatgaa aaatctcctc
    30961 tgctgtctct ttaaaatcat gttccatcag taaatatgga tgacgattct ctaactggta
    31021 cttgtagcga tcctgtaaaa tatagccctt atagagatag acttgagcac aaagctgact
    31081 gagttcatag gtgacatggt cctctgtata atcccccaat agttcctcct tcttcatttc
    31141 ttgaatcaat tgcgtcagta aatctgccaa ctgccctcca aaaccaagaa tatactccat
    31201 agtatgaaga ggaagaatgc gatgagatag gagaaaagag aagaatatca tcatctcacc
    31261 atcctcaact cctagtggaa tatgttgccc agcaaaaaag gacggaacct ttctcagcaa
    31321 acgaagataa aagatattgt caaaataccc tcgcattttc tcttctatga cttgaaactg
    31381 acaagcattg acccgaagac gttgttgact gatgtgagcc cagagaacca agtccaattt
    31441 ctgccccaca gacaaacttg caccgcagat ttcctctaaa ttggcaatct cctgttttct
    31501 ctctggtttc tgcatgtgac cttcccattc ctgactcgac cagacctttc ggaaaagaca
    31561 gaaatagaaa tagcgaatct gatgctctgg acctcgccaa cgtccatttt ggatggataa
    31621 atcaaattct gacagaatct gatttaaacc agccaagtga cgaccaagcg tagcctcgct
    31681 aatcaccaat tcttgagcca gctgatgggc taaaaactgt tggtggtaga gaagataaac
    31741 caaaatctgg tatttaacag cactctccaa aaataagctc cgaatatctc tccccttggt
    31801 agctgcaccg atagacagac gcaaattttc attttctgag tgaatagtca gctctaagcc
    31861 actatccaaa gccttgtcat tgagcagggt gacatatttg gttagggttg cttttgaaaa
    31921 tcctgtttct tccattacag ccttgacggt cgtctgagac tcttgtaata gaaaggaaag
    31981 gattgaaaat tgaccacact cagctttctc catcaaatct cctaaataca tttgttaccc
    32041 ctttcatttt ctaccttaag catagcataa atcttacaaa tgctgaaata atctgtttct
    32101 ctttttattt tcatgctgat ttcctggtcc attatcctga aaatcagtaa acacacggct
    32161 ccccctctgg gcatttttat gctaaaatag tagctatgaa taaaattatt aaaactatat
    32221 cagaaagcgg agcctttcgt gcttttgtcc ttgacagcac ggaaaccgtc cgcactgctc
    32281 aagaaaaaca ccaaacccaa gctagctcaa ctgtagcgct tggtcgaact cttatcgcta
    32341 gccagattct cgcagccaat gaaaaaggaa ataccaaact tacagttaag gtgttgggat
    32401 ctagctctct aggtgctatt atcaccgtcg ctgataccaa ggggaacgtc aaaggctacg
    32461 ttcaaaatcc tggtgttgac atcaaaaaga ctgcgactgg tgaagtccta gtcggacctt
    32521 ttgttggaaa tggtcaattc ctcgttatca cagactacgg tactggaaat ccttacaact
    32581 ctataactcc cctcatctcc ggagaaatcg gtgaagacct tgccttttac cttactgaaa
    32641 gccaacaaac gccttcagcg gtcggcctca atgtcctttt ggacgaggaa gacaaggtca
    32701 aggttgcagg tggtttccta gttcaagtct tgccaggagc caagaaagaa gagattgctc
    32761 gctttgaaaa acgcatccaa gaaatgccag ctatctctac tcttctcgaa agcgacgacc
    32821 atatcgaagc cctcctcaag gctatctacg gggacgaagc ctacaagcgt ctttctgaag
    32881 aagaaatccg tttccaatgt gactgtagcc atgaacgctt tatgaacgct cttgccagcc
    32941 ttccaagctc agacttacag gaaatgaaag aagaagacca cggggcagaa atcacttgtc
    33001 aattctgcca aactacttac aactttgatg aaaaggacct ggaggaactc attcgtgaca
    33061 aatcttaata caccttttat gattggcaat gttgagattc ccaatcgtac cgttttagcg
    33121 cctatggctg gcgtgaccaa ctcagccttt cgtaccatcg caaaagagct cggagctgga
    33181 ctcgttgtaa tggaaatggt ctctgacaaa ggaatccaat acaacaacga aaaaaccctg
    33241 cacatgcttc atatcgatga gggcgaaaac cctgtctcta tccaactttt tggtagcgat
    33301 gaagacagcc tagcacgcgc agcagaattc atccaagaaa acaccaagac cgatatcgtc
    33361 gatatcaaca tgggctgccc tgtcaacaaa atcgtgaaga acgaagctgg agctatgtgg
    33421 ctcaaggatc ctgacaagat ctactctatc atcaacaagg ttcagtctgt ccttgatatc
    33481 ccccttactg tcaaaatgcg taccggatgg gcggacccat ctctggcagt agaaaatgcc
    33541 ctcgctgctg aagctgcagg tgtttctgcc ctcgccatgc atggccgtac ccgtgaacaa
    33601 atgtatactg gccacgcaga ccttgagacc ctttacaagg ttgcccaagc tctaaccaag
    33661 attccattca tcgccaacgg tgatatccgt actgtccaag aagccaagca acgcatcgaa
    33721 gaagttggtg ctgacgcagt catgattggc cgagctgcca tgggaaatcc ttacctcttc
    33781 aaccaaatca accattactt tgaaacagga gaaatcctac ctgatttgac ctttgaagac
    33841 aagatgaaga tcgcctacga acacttgaaa cgattgatta acctcaaagg agaaaacgtc
    33901 gccgttcgtg aattccgcgg cctcgctcct cactatctcc gtggaacatc tggcgctgcc
    33961 aaactccgtg gagccatttc acaagctagc accctggcag agattgaagc tctcttgcaa
    34021 ttggagaagg cttaatagtt taaaacccgt aactctctta aagagtctct tgagtgccgc
    34081 cattctttcc tcatcaaaaa aactccgtag tctctagcgc cataaatccg gctagagatt
    34141 acagagttat tttttaatct aaacttccta caagggtata gtatctactg aaaggatatg
    34201 gtatttgtag ggaatacttt aaagagttct tacaggaagc cagcattaac gagttacatt
    34261 aggtttagtt tacccattta ccattggcat tgactctata gccacctaca gttgtgttga
    34321 ctgcaagggc acctgagcca ttgacatagt accatttgtc tgatactttg aaccattggc
    34381 tttctttcat agcccctgat gcttcaagat agtaccatgt atctccatct ttcagccaac
    34441 ctgttgccat cgaaccgtta gcatt
//
LOCUS       DAVIME010000021        33763 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVIME010000021 DAVIME010000000
VERSION     DAVIME010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.021"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(483..1172)
                     /gene="rplA"
                     /locus_tag="VV588_001055"
     CDS             complement(483..1172)
                     /gene="rplA"
                     /locus_tag="VV588_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU7083412.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1380..1805)
                     /gene="rplK"
                     /locus_tag="VV588_001056"
     CDS             complement(1380..1805)
                     /gene="rplK"
                     /locus_tag="VV588_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU7083413.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2114..2830)
                     /locus_tag="VV588_001057"
     CDS             complement(2114..2830)
                     /locus_tag="VV588_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU7083414.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKAQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELLKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2911..3715)
                     /locus_tag="VV588_001058"
     CDS             complement(join(2911..3345,3347..3715))
                     /locus_tag="VV588_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU7083415.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGVHESNLLRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     SHDMKLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(3723..4164)
                     /locus_tag="VV588_001059"
                     /pseudo
     CDS             complement(3723..4164)
                     /locus_tag="VV588_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(4166..5203)
                     /locus_tag="VV588_001060"
     CDS             complement(4166..5203)
                     /locus_tag="VV588_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU7083416.1"
                     /translation="MNQTINYIKELTAIASPTGFTREISDYLVHTLEKLGYQPVRTAK
                     GGVNVTIKGQNDEQQRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIELPVTTHFAFSVFEE
                     VGHGANSNIPTQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(5301..6626)
                     /gene="brnQ"
                     /locus_tag="VV588_001061"
     CDS             complement(5301..6626)
                     /gene="brnQ"
                     /locus_tag="VV588_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU7083417.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAVAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6797..6889)
                     /locus_tag="VV588_001062"
     CDS             complement(6797..6889)
                     /locus_tag="VV588_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU7083418.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6932..7084)
                     /locus_tag="VV588_001063"
     CDS             complement(6932..7084)
                     /locus_tag="VV588_001063"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU7083419.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDELAALHLEGTHNLPLSQ
                     LADSYD"
     gene            complement(7244..7822)
                     /locus_tag="VV588_001064"
     CDS             complement(7244..7822)
                     /locus_tag="VV588_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU7083420.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFVAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     DFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMSKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7876..9276)
                     /gene="pepV"
                     /locus_tag="VV588_001065"
     CDS             complement(7876..9276)
                     /gene="pepV"
                     /locus_tag="VV588_001065"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU7083421.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFDFAGPAKEYLDITGKILLNDHEGESLKIAHVDEKMGALSMNAGV
                     FRFDETCADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9289..9894)
                     /locus_tag="VV588_001066"
     CDS             complement(9289..9894)
                     /locus_tag="VV588_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU7083422.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10065..10865
                     /locus_tag="VV588_001067"
     CDS             10065..10865
                     /locus_tag="VV588_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7083423.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11043..11876)
                     /locus_tag="VV588_001068"
     CDS             complement(11043..11876)
                     /locus_tag="VV588_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU7083424.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(11866..13710)
                     /gene="uvrC"
                     /locus_tag="VV588_001069"
     CDS             complement(11866..13710)
                     /gene="uvrC"
                     /locus_tag="VV588_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU7083425.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13749..14450)
                     /locus_tag="VV588_001070"
     CDS             complement(13749..14450)
                     /locus_tag="VV588_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU7083426.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(14529..15761)
                     /gene="murN"
                     /locus_tag="VV588_001071"
     CDS             complement(14529..15761)
                     /gene="murN"
                     /locus_tag="VV588_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU7083427.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15766..16986)
                     /gene="murM"
                     /locus_tag="VV588_001072"
     CDS             complement(15766..16986)
                     /gene="murM"
                     /locus_tag="VV588_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU7083428.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17098..17877)
                     /locus_tag="VV588_001073"
     CDS             complement(17098..17877)
                     /locus_tag="VV588_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU7083429.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17946..19607)
                     /locus_tag="VV588_001074"
     CDS             complement(17946..19607)
                     /locus_tag="VV588_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU7083430.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19782..22004)
                     /gene="recJ"
                     /locus_tag="VV588_001075"
     CDS             complement(19782..22004)
                     /gene="recJ"
                     /locus_tag="VV588_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU7083431.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22281..23039
                     /locus_tag="VV588_001076"
     CDS             22281..23039
                     /locus_tag="VV588_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU7083432.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            23079..23843
                     /locus_tag="VV588_001077"
     CDS             23079..23843
                     /locus_tag="VV588_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU7083433.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23856..24533
                     /locus_tag="VV588_001078"
     CDS             23856..24533
                     /locus_tag="VV588_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU7083434.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24543..25202
                     /locus_tag="VV588_001079"
     CDS             24543..25202
                     /locus_tag="VV588_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU7083435.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25460..26650
                     /locus_tag="VV588_001080"
     CDS             25460..26650
                     /locus_tag="VV588_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU7083436.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVSSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26971..27852)
                     /locus_tag="VV588_001081"
     CDS             complement(26971..27852)
                     /locus_tag="VV588_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU7083437.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27991..29319)
                     /gene="vncS"
                     /locus_tag="VV588_001082"
     CDS             complement(27991..29319)
                     /gene="vncS"
                     /locus_tag="VV588_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU7083438.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29316..29972)
                     /gene="vncR"
                     /locus_tag="VV588_001083"
     CDS             complement(29316..29972)
                     /gene="vncR"
                     /locus_tag="VV588_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU7083439.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30021..30104)
                     /gene="pep27"
                     /locus_tag="VV588_001084"
     CDS             complement(30021..30104)
                     /gene="pep27"
                     /locus_tag="VV588_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU7083440.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(30284..31663)
                     /gene="vex3"
                     /locus_tag="VV588_001085"
     CDS             complement(30284..31663)
                     /gene="vex3"
                     /locus_tag="VV588_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU7083441.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31715..32362)
                     /gene="vex2"
                     /locus_tag="VV588_001086"
     CDS             complement(31715..32362)
                     /gene="vex2"
                     /locus_tag="VV588_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU7083442.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32375..33652)
                     /locus_tag="VV588_001087"
     CDS             complement(32375..33652)
                     /locus_tag="VV588_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083443.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9534 a         7690 c         6300 g        10239 t
ORIGIN      
        1 tccacgtttt tcaaggactg gttttgatat agcacgttta agtaccgact tctgagctac
       61 tatagtagat tgaaactaga atagtacacc tctacttcta aaacattgtt agaaatcgat
      121 ttgactgtcc tgaacgattc gtcctattct tatttcattt tattataatt gatagtggtc
      181 gccccagcca gataccttat ccgctatata cgccttatta tcacgttcct gttcgtagag
      241 ccacgatttc gctatccctt cctctgacga ttcttatttc cagcgtcaga cttaaaacgg
      301 tctatcccca gaccgtttta atccgctacc tcacgatagt cagacttggg aatcgctatt
      361 gggttcaccg gtagtaggtg cccaccgagg acttacacct cagatatacg acatgcccgt
      421 cgtacatcaa aaaaagttga gacatagtgt cttcaacttt tttacattac tttaactact
      481 gattaaagtg agtttacgtc aactttgata ccaacacctt gagtagttgt gatagtcaag
      541 tttgttacgt aagttccttt agctgtagct ggttttgctt tttggattgt ttcgttgaaa
      601 gctttaaagt tttcaaccaa tttttcagct tcaaatgata ctttaccgat gattgcttga
      661 acgttacctg cacggtcagc acggtaagtg attttaccac ctttagactc ttcaactgct
      721 ttagcaacat ccattgttac agtaccagtt ttagggtttg gcatcaagtt acgtggtcca
      781 aggacacgtc caagacgtcc aacaagagcc atcatatcag gtgtagcgat aactacgtcg
      841 aagtccaacc aaccgtcgtt gattttagca acaaggtcat cttcaccaac aaagtctgca
      901 ccagcagctt ttgcttcttc agcttttgca ccacgtgcga aaacaagaac acgtgaagtt
      961 ttaccagtac cgtttggcaa taccattgct ccacggattt gttggtcagc ttttttaacg
     1021 tcgatgttca agttgtaagc aacttctaca gttgcgtcaa attttgcaaa gttagtttct
     1081 tttgcaagtg ctacagcttc ttctacactg tatgcttttg tgctgtcgat tttctcaaga
     1141 gcagcacgaa gttgtttgct ttttttagcc attttctatt ctccttgtaa gtggttcaat
     1201 cgattttcat ctcccacgtc acttctcgaa atgatgaagt cttgcgggtt ttcagtctac
     1261 tatttttctc ttcctacggc cttaagctcc cttgctgtac ccaagtacaa ggctcagtca
     1321 cttgcctagt atgaaaagca actaatagac tgctgtgaga ttttctactg tgttattgat
     1381 tagtcaacaa cagtgaatcc catagaacga gcagtacctt cgatcatacg cattgcagac
     1441 tctacgtttg ctgcgttcaa atctggcatc ttagtttctg caatttcttg tacttgtgca
     1501 cgagtaactg tagcaacttt agttttatta ggtgtacctg atcctttttc aacacctgca
     1561 gcttttttca aaagaacagc agctggtggt gtttttgtaa cgaaagtaaa tgatttgtct
     1621 tcgtaaactg agataacaac tggaatgatc ataccagctt ggtcagctgt acgagcgttg
     1681 aactcttttg tgaatcccat gatgttgata ccagcttgac caagagcagg tccaaccggt
     1741 ggagctggtg tagctttacc agcagggatt tgcaatttta caagtttttc gactttttta
     1801 gccattttta aatcctcctt tgtggttttg gcggtaatta gagattttta cctcccacaa
     1861 gtatgttttt cacataccca tccattatac actatttatc tggaattgca agagaaaagt
     1921 ttatttttta tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgctc
     1981 aaagtacagc tttgagattg cagataaaac tgacgaagtc agctcaaaac actgttttga
     2041 ggttgtgaat agaaccgacg cagtcagtag gtaaggcgac gctgacgtgg tttgaagaga
     2101 ttttcgaaga gtattaatcg acgtagtctc cgccttcaaa gccatagtat tcttccaaac
     2161 tgagaccact tgcagcaatt tctttagctt cttttcctac ataacgcagg tgccattcct
     2221 cagccatata gcctgtttcc ttttccttgc ctttgagata acggacaaca aagccataat
     2281 cagctgcatg atccaagagc cattgggctg ctttttcttc tgtcaccaaa tcaccatcag
     2341 tcccaatcac atcaaaggcc aagcctgtct ggtgctcact atagccaggt cgggcagagt
     2401 aacggtcagc tgctgccttc ccatcttggt taacataatc ttgatagagc ttggtctgag
     2461 tttcataact tctaaaacca ctgtaatgat cgctaatcgg gaaacctgcc tcttgcattg
     2521 ctttgatgag tttgagcaat tctgccttgg ctgtcggatt ttcacctgga ttgtagtctt
     2581 tagacaatgg atagtgttta ttggctacga tgatttcatc gtatttccct tggatgctgt
     2641 agtagtctcc tttgttaacc acttctgctt ttttctgggc agctccttga gccttacttc
     2701 ctactgttcc atcagcttta gctgtttgtt ctgttttagc tgctccatct tcattttttg
     2761 ctttttcttg tgaacaagct gctagactca aggctagcaa agctgtcaag actaggtatc
     2821 tttttttcat ttctactcct ttatttctaa tagtttatct acttctaacg ataaacgttt
     2881 gactaatctt ttaatagact tcctgcaaaa ctagaatcct agttcatgat tgataatacc
     2941 agcaatcaaa ttcattcgta atccgaagcg tttacgatga tttcgatagg ttgttgaaaa
     3001 cattttaaac gtttttactt tggcaaagat gttctcaacc ttgcttctct ccttagatag
     3061 cgcatggtta caggctttat cttcagctgt tagcggcttg agtttgctgg atttacgtgg
     3121 agtttgtgct tgaggatata tcttcatgag cccttgataa ccactgtcgg ccaagatttt
     3181 accagcttgt ccgatatttc tgcaactcat tttgaacaac ttcatatcat gactatagtt
     3241 cacagcgata tccaaagaaa caattctccc ttgacttgtg acaatcgctt gagccttcat
     3301 agcgtgaaat ttctttttac cagaatgatt cgctaattct ttttttaggg cgattgattt
     3361 gtacttccgt cgcatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaatcg
     3421 taacaccact ttgaacaaga gttacttcaa cccatcggct ccgacggagt aagttgcttt
     3481 cgtgaacacc aaaatcagcc gcaatttctt cataagtgcg gtattctcgc acatattgaa
     3541 gagtggccat aagaaggtct tctaggctta atttaggttt tcgtccacct tttgcgtgtt
     3601 taagttgata agctgttttt aatacagcta gcatctcttc aaaagtcgtg cgctgaacac
     3661 caacaagacg cttaaatcgt gcatcagtta gttgtttact tgcttcatca ttcatagaac
     3721 tactatacca tattttgttt cgcaggaagt ctaatctcat ccggttttgc ttggcgggtt
     3781 tctgcggtca ttttttcaaa agggacccac cagactggcc cacagtcctt gagaccgtgg
     3841 ccattcatat cacctcttcg tctagggaaa aggtgccagt ggagatgggc atcgccattt
     3901 cctagaagtt caatattcat tttctcagca gtaaagccct tggcaactgc ctcttggact
     3961 aaactcattt cttctagaaa atggagtctt gtgtcctttt ctaaaatggt gcaattccgt
     4021 gacatgttcc ttggctagaa agagactata gcttgcaaaa tactgatggt ctccaatcac
     4081 aagatagcct gttcccaact ctttgacaaa gtagggattt tctcccttct tgatgagctc
     4141 aattctctgg caaataaggc acatatcaat ctactaaatt gcttctaaga taggcatcga
     4201 ccattcgttc tgttgcgacc accgagtcaa tatgagtgcg ctcataagaa tgactagact
     4261 cgatacccgc accaagaagg gcatgcttga cctctgcccc tgcagacata gccgctgaag
     4321 catccgaacc ataaaatgga tagatgtcca gcttaaaagg aatatcttgc tctttagcca
     4381 aggcaaccaa gtgttgacgg aagtcatagt gataaggacc tgaagcatcc ttgacacaga
     4441 tagatactgt gtactcatct gtctgctggt catctcccat tgcccccata tcgacagcta
     4501 gatattccac cacttgagtt ggaatattgg aattagcacc gtggcccacc tcttcgaaaa
     4561 ctgaaaaagc aaaatgagtt gttactggca attcaattcc ctcttcctta taaacacgaa
     4621 gaagattgag caaaattgct gcgctgacct tatcatccaa gtggcgagac ttgataaaac
     4681 cagtctctgt cacaacagtt cgcggatcga aactaataaa gtctccaacc tcaataccca
     4741 aggcgcgcgt ttctttttca ttggttactt ttgcgtccaa acgcacttcc atattgtcct
     4801 gcgtacgttc tgcagttcct gcatccttgt agacatgaca agaagtctgg tggatgagga
     4861 tggtcccaga taccgtttga cctgtgctag ccacatgaac ggtacagttt tctccttcaa
     4921 tcatgttcca aggaaaacca ccaatacgat ccaatttgag acggccatct ggtttgactg
     4981 cacgaacaat agcacccagc gtatccacat gggctgtcac atagcgttgt tgttcatcat
     5041 tttgaccttt aatggtcaca ttgacaccac ccttagctgt acgaacaggc tggtaaccaa
     5101 gtttctctaa agtatggact agatagtctg agatctcacg agtaaagccc gttggagatg
     5161 caatagcggt tagttctttg atatagttta tagtctgatt catttcttca cctctttcgc
     5221 tacctattat aacacattta tcatcggata aaaaaagaaa atcactcctg tagacttggc
     5281 tacaaaagtg atttaagtga ttattccatt tcaaaaacat cgctttcttg cttgtttggt
     5341 agaaccaatg agagcaagat tccaacaatg gctggcacca accatgggag agatgccttg
     5401 gcaaaaggaa gaacgctaac aagatttgca agaaactcaa ccttaaacga gcttcctagt
     5461 acgcttgcaa tggcaataac tgtaaccaca gcaattgtca actgcatacc tggttttgaa
     5521 agggcaacaa atttgttgac aatgacaatc ataacgatag caatcgtgat tgggtacaag
     5581 ataaccagta ctggaattga gtacttgata atcgcatcaa gacccaaatt ggcaatagca
     5641 aatccaatca aggtaaaggc tgtcgcataa accttgtagc tgatttgtgg gaagcgctca
     5701 ttaaagaact cagctgttga cacaatcaaa ccaacagtcg ttgtgaagca ggttacggta
     5761 accatagctg caaggaagag ttgagctgtt gagccaaaga tttcttgagt ggcttgtgac
     5821 aagatgtaaa cacctggtgt tccacccttc atcgcttcag ctggtactgg gaaatgattt
     5881 ccaagaaaac ctaaaccgat gtaaagagcg ctgaaggcaa gggcaacaac gataccaaca
     5941 acccaaatag ttgaaatgta ttctttctta cttgaaaatc caagttgttt caaggtttga
     6001 actgcgatta cgctaaaggc cactgaggca agggcgtcca aggtattata accttctagg
     6061 aaacctgtac caaaggcaga agcttgataa gcagctgaag cagcttgagg acttgttcca
     6121 ccatatttga tagctcccag aacgaccaag ataacaatca aaattgcaaa gactggcgtt
     6181 aaaatacgtc caatgcggtc taagattttt gatggattaa gcgaaatcaa ataggctacc
     6241 gcaaaataca gaaccgtaaa tacaatcaag ccaagtcctt tatttgcatc cgacaaaagg
     6301 gggctaatcc ctacttcgta agctgttgta gcagtacgtg gggtagcaaa gaatggaccg
     6361 attgacaagt aaagaactga gaggtaaaga gtcgcaaacc aaggcgctat cttcgttgaa
     6421 atctcgtaga tatatccttt aggatttagc gttccaataa taagggtcaa gacggcgata
     6481 ccaacgcctg aaaagacaaa acctgcgatg gcaggaagaa aatgttctcc agatagagca
     6541 cctagagaag gcggaaaaat caagttcccc gcaccaaaaa atattccaaa caggagcaaa
     6601 cctgttaggg tacctttttt agccataaaa atctccttca tatttataaa atactgacct
     6661 agtataccac gattaggagt ctgaaaaaag catcacgagg caaatattaa atgttttcaa
     6721 ttttcttaaa aataagaatt atctaaaaac aaaactctcc tacccagtcc acaccaagta
     6781 ggagaaatgc aaaattttaa agttcttcaa aggctaacat gccaccctgg acattgataa
     6841 cattataacc ttgttctaac aggaattggc aagcacgcgc cgatctcatt ccagatttgc
     6901 aaataatata atgcaagcga tctttgtcca attaatcata actatcagcc aattgactaa
     6961 gcggtaggtt gtgggtacct tctaaatgaa gagctgcaag ctcatccact tctctcacat
     7021 ccactagaga aagctggtcg ttttggtaaa gctgataaaa tgcgtcaaag gctatttctt
     7081 tcattctttt tcttctaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta
     7141 ccgtgcgtat gttaccgact tcgtcagttt tatctgcaac ttcaaagctg tactttgagc
     7201 agcctacgac tagcttccta gtttgctctt tgattttcat tgactataaa atggttttaa
     7261 ttcttttttt caaatctggc actacttctg cctcaaacca aggatttttg gacatccaga
     7321 tttgatttcg tggtgatggg tgaactagcg gaaaataggc tggcagatag tctttatagt
     7381 gtttcaccct ctccgttacc ttcccactga ttttctcctg taaatagtag gcttgggcat
     7441 attgcccaat caagagggtt aactgaatat caggcaattc ctgtaagagc tgcggatgcc
     7501 atttttctgc aaaatctgta cgaggcggaa gatcacccga cttgccatgt cctggaaagt
     7561 agaaatccat aggcaaaaca gcaaaataac ctgaattgta aaaggtatct tcatccacac
     7621 ctagccagtc ccgcaagcgg tcaccacttt tatctttcca gtaaaggcct gcttcttgag
     7681 ttttaagtcc cggagcctga ccgatgatat tgatgcgagc agtttttggc gctacaaaga
     7741 gaggctcaat gccacgctct gtatagctgg cattctgcga atccgccatg atagcctgtt
     7801 tgattctttc gatttgagac atctactttc cctccaaaaa gaagtccaag cataagatct
     7861 cagacttcta tcgttttatt tgatcaattc gtaaatagct tcggcataaa ttgctgctgc
     7921 tcggaagaga tcgtccaagg caataaattc attggcttgg tgcatagtat caattgagtc
     7981 tgggaacata gcaccatagg caactccgcg ctctaacaag cgaccaaagg ttccaccacc
     8041 gatgacttgt tcatgacctt gtaggcctgt ttgtttttca tagacattca acaaggtttg
     8101 cacaagtgga tcttccattg gcacatagtg aggggtatga ccatgttctg atagactgac
     8161 agaagcaact ggcaagtttt ctaggattga cttgatttgt tctggacttg ttccttttgg
     8221 atagcggatg ttgagggcaa tggtattatc agcacatgtt tcatcgaagc ggaagacgcc
     8281 tgcattcata gaaagggcac ccatcttttc atccacatga gcaatcttga gactttcacc
     8341 ctcatggtcg ttcaagagaa ttttaccagt gatgtcaagg tattctttgg ctggaccagc
     8401 aaagtcaaac tggctaagga agagggctag gtaagtcgca ccattgacac ctgaagcagg
     8461 catagcaccg tgggctgatt taccaatgat cgtcaccttg tatttgccag cttcttcttg
     8521 gagttctcct ctaagtttgt gttctgcaac aaaggcatct agtttagctt gcaagtcagc
     8581 caaatcacct gaaacgactg ctgttgctga ttctggtacc atattttcac gtaaaccacc
     8641 tgtaaagctg tgaagacggg cagcacctgt attttctcct gcaaagtgga ggtattccgt
     8701 gatatttcct ttttcaccat tgatgatagg gaattcagcg tctggagaga aaccgaaatc
     8761 tggtttggca agtcctacgt gctcaaagta gtagtccata tctgcccagc ctgattcttc
     8821 gtctgttcca acgatgaagc gaactttctt agaagttgga agacccaatt ctttgatgat
     8881 tttcaaacca tagtaacaag ctgttgtagg acccttatcg tccgaagccc cgcgcgcata
     8941 aaggcgacca tctttgatag ttggtgtgta aggatctgta tcccaaccgc taccagctgg
     9001 aaccacgtcc atatgggcaa agattccgag aacttcttct ccatcaccaa actcaaaatg
     9061 tcctgcatag ttatcaacat ttttagttgg ataaccatca cggtctgcga tttcaaggaa
     9121 tttttccaag gcttttactg gaccaggtcc aaatggatgt tgggcatcag ccttgctatc
     9181 atcacgttct gagttgattt ccaaaaggct aaacaagtca gccaagaggt cttctttgcg
     9241 tttttctact tctgctgtaa aatcaattgc tatcattttt tcttcttcct atcttttttc
     9301 gatgatttca tctactggca agcggtagct tggttccaat ttgtcgtctg tgtaacccac
     9361 tgtgatcaag agttctgggc ggaaacggtc ttcgatttcc aaaacttcat taacttttga
     9421 tttgtcaaaa ccaaggataa tattggaacc aattccttgg tctgtaagag cgagaaccaa
     9481 gttcatagca accaaacctg cattgagtgc taggtagtcg ctgacttgtt gttcattgta
     9541 gcgtgcaaat tcagctggca aatttttcat gaagtattga agttgttctt ctgagaaatt
     9601 gttagcacca ccaactcggg caatcttacg agcgcgtttg gcaaggtctg tatctgtaaa
     9661 tagggcaatg gttacaggtg ctgatgatac ctgttcaaaa ttggaaccat aagctaactt
     9721 tgccagttca gcatttttct cacataccac cacaaatttc caaggctggc tgttgtgggc
     9781 gcttggcgcc aaggttgcaa tttcgatagc cgtacgcaca tcttttggat caacaggctt
     9841 atcagtgaaa tgcttggtcg catgacgttt tttatttaat tcaagaaatt tcataatcga
     9901 tttccttttc taattctact gcttccattc taccataatt tgaaagagct tgcagggatt
     9961 tttcatgatt aagtttttct atcacagaca taaaagatat atattggttt atcaggaaag
    10021 tttctgataa actagcaagt actttacatt tgaatggaga cagtatgaaa aaatttagcc
    10081 tattactagc tatcctacca tttttggttg cctgtgggaa tcaagctaca cccaaagagt
    10141 ccagctctca aaagacaatc gtccttgcta cagctggcga tgtgccacca tttgactacg
    10201 aagacaaggg caatctgaca ggcttcgata tcgaagtcct aaaagcagtg gatgaaaaac
    10261 tcagcgatta cgagattcaa ttccaaagaa ctgcttggga gagcatcttc ccaggacttg
    10321 attctggtca ctatcaagca gcagctaata atttgagtta cacaaaagag cgcgctgaaa
    10381 aatacctcta ctcgcttcca atttccaaca atcccctcgt ccttgtcagc aacaagaaaa
    10441 atcctttgac ttatcttgac cagatcgctg gtaaaacaac acaagaggat accggaactt
    10501 ctaacgctca attcatcaat aactggaatc agaaacacac tgataatccc gctacaattg
    10561 atttttctgg tgaggatatt ggtaaacgaa tcctagacct tgctaacgga gagtttgatt
    10621 tcctagtttt tgacaaggta tccgttcaaa agattatcaa ggaccgtggt ttagacctct
    10681 cagtcgttga tttaccttct acagatagcc ccagcaacta tatcgttttc tcaagtgacc
    10741 aaaaagagtt taaagagaaa tttgataaag cgctcaaaga actctatcaa gacggaaccc
    10801 ttgaaaaact cagcaatacc tatctaggtg gttcttacct cccagatcaa tctcagttac
    10861 aataacactc ttcgaaaatc tcttcaaacc acgtcagctt tatctgcaac ctcaaagctg
    10921 tgctttgagc aacctacggc tagcttccta gtttgctctt tgattttcat tgagtataag
    10981 atatataaaa gcgattggac taccaatcgt ttttagtttg cattggttat tttaggaaac
    11041 tcttacaaaa aatcaaaaaa attcttcaca tcctctacat acctatgctt ttctattaag
    11101 cttgctaata gtttcagatt gtgcctctga tagttatctt cacgacgtag ttcttcatac
    11161 atttcgataa agggaagccc cttggatttg gccaattcta actcagcctc gtaatcataa
    11221 gcaactttac gaaattggat attgagtaat tccccatctt caacctctat cacggcatac
    11281 tgggcacggt gattttttaa cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga
    11341 ttgatgattt gttgcccttt actgccgtag cgaagcaact gcttgtgaac atgaccataa
    11401 actgccacgt ccgtttccgc atctagcagt tggtcaaatt tctctgtatc attctcaact
    11461 agcaagtcac caccatagtt tttgtcaggt aaattatgag agatagaaaa gcgcaatccg
    11521 tcaatttctt tcttttccag caaaggcaag cttcgtagcc agacaatcgt tgcaggatcc
    11581 attcgctcca tcaaaaactg ggtcatgcgc attgactgga tttctttcgg atattccaaa
    11641 ccatattcgc catccaagac ctcaaggaca cgatcatccc aattgcctcg aacacttgct
    11701 gtgataggaa ggtcctttag cagggcgact aagtcatttg cgcctggacc aggaagaaaa
    11761 atatctccct gaagccaata ttcactggcc ccttgatttt tagcatctgc aatcactgct
    11821 tctagcgccg tcgcattgcc atgaacatct gataaaattg cgattttatg gttcattgtg
    11881 gtttccttcc gtttggtaat ctactctttc ttctgctact tgaggcaagg cttctccctg
    11941 cgggttcaac tttctttgca cagcctctgc aacgactcta ggtaccccaa cttcgacaat
    12001 ctcatccaca ctggcttcct tgattttggt caaagacttg aaatgcttca taagattctg
    12061 cttgcgttta ggtcccagac cgtcaatccc atccaattga gatgagaaag aatttttgga
    12121 gcgcagttgg cggtggaaag tgatagcaaa gcggtgcacc tcatcttgga tgcgttggag
    12181 gaggaaaaat tcctgagaat tgcgagacaa gtccaccacc tcaagcggat ctccaaagag
    12241 caattcatgg gtttggtgct tatcattctt ttgcagccca gcaattggaa tatccaagcc
    12301 cagttcctct tggatgactt gcttagcaat attgacttga ccttgccccc catcaatcac
    12361 aatcaaatct ggaggagtca aagcctcacg ctgtactcga ccatagcgtc tgcgaatgac
    12421 ttctctcata ctagcatagt cgtccggccc aacaacggtt tttatcttgt acttacggta
    12481 atctttttta cttggcctgc cgttaacaaa gaccaccatg gctgaaacag gactggtccc
    12541 catgatgttg gagttatcga aggactcgat gcgaactgga gtcggaattt ggagcaaacg
    12601 tcctagattt tcaatagctc cttgggtctt ttcgactgat ttttctagca gattgaactt
    12661 ctgctctaga ctaacacgag cattttttat ggctagattg accagctgtt ttttctctcc
    12721 acgttggggt ttgagaatct tggtatccac caaagccttg acagcttctt cgtcaatatc
    12781 ctgcggaatc agtacctcat tgggaactag gtgagatttt tcttgataga attgtcccac
    12841 ataggtcaag aaatcctcat ctggatcatt gaagtagggg aagagattga catcgcgctc
    12901 gatgagcttg ccctgacgaa caaagaaaac ctgcacacac atccagccct tatccacata
    12961 gtagccaaag acatcgcgat tttggagatc cttagccatg acccgttgct tggttcgaag
    13021 tgttccaatg gcctgaatca ggtcacggta ttccgctgcc cgttcaaact ccatactttg
    13081 tgctgttact gccattttac tcttgagatc atcgatgatt ttgtcatcct gacctttcag
    13141 aaaatcagac acctcctggg ccatggactt gaaataggcc tcgtcattct tacagatggt
    13201 gtgggccata cattggccga tatggtagta aaaacagacc ttagagggcg ggttggtaca
    13261 ttttcgaaaa gggaaaatcc tatctagaag tcgcttgatt tcattggctg cccccacatc
    13321 tggataaggg ccaaaataaa gaccaccgtc ctttttgacc tgacgagtaa tgataagccg
    13381 tggatagtgc tcattggtga ttttgataaa aggataagac ttgtcatcct tgagcatgat
    13441 attgtacttg ggcttatttt ccttgatcag gttgatttcc agcagaagcg cctcaatatt
    13501 agactccgta acaataaatt caaaatccac aatttcagac accaaggcct ctgttttggt
    13561 atcatgactt ccacggaaat aagacctcac gcgattacgc agatttttag cctttcctac
    13621 atagataatg gtgccgtttt tatccttgta aatgtagcaa ccagggctgg tcggcaagag
    13681 ctctagtttt ggtttaatca agttgttcat agttccatta tagcaaaaaa gtagggaaag
    13741 atagtaccct actcattagt ctcatatatt tttcggaggt ttgcaacatc ctcttcctgg
    13801 ataccataaa aggaacctgc tggttgcatg acagacttct catctgtatg gtccaagcca
    13861 atcgcatgac ctaactcatg ttctgccgta tggacaaggc gttcatagga atagccatag
    13921 tatggattgg acaaataata atgattcaac cgcaccgtta cggacaagaa ttgccctgtt
    13981 aagagattag tttgactttc cgcctctcct gccacaggag tgcctccgtc gttcatctcc
    14041 gtagccgtaa tatccgcctt actagactca gtcacgagtt caaagttaaa agcaccagtt
    14101 tgattccagt tctggattgc ttctaaataa gcctcttgaa agcgtgaatc catctgcgga
    14161 tccaggtaaa tacgagcaga ggcctgtggc caccttcctt cagaatgctg gtgactatct
    14221 gtctggctta acttaggcag ttgccctgtt ttctcccatt ggtcaatact ttgttgacca
    14281 atttttactg accgttctgc ttgctttagc gctccttgaa aatccccgtt cagataccag
    14341 agaagtccga aagcaagcac acataagagc acaactatcc aaaccagacg ccaaaacaaa
    14401 cgccacacaa aagaaaagaa agcccctatc aaacgaaaaa gccagcgcat gtctctccac
    14461 ctttctagca aataaaaatt attttactaa aagaagctaa aagaaatcta aatactgact
    14521 ttttcatctt aacgtcctac tatttttttg agtaactgga tagctttgta ttttaaagga
    14581 gatggatggt aacggaaagt acctgctttg cgtacaatat agccattaaa attctgttta
    14641 aaacgcaaaa caccatcact tccatcaaaa atcccttgaa tgcctaggaa gttgtattta
    14701 ggtattccac gttttatgct ttccaacata acatattttt gaagcagtgc aggggcatag
    14761 aacttattaa actcagtgta ggaaccacta aagagataag tcgtttcctg aggcatataa
    14821 acaaataaac tcccagctaa aacaatatct tcttctccat atttttcaat caagtctcgc
    14881 gcttctgctt ttcgaacttc aaacgtttca aattgactag aatattctct cagttgattt
    14941 tgttttttct cagaatgagg atttttactc aaatcaagtc gcaacttgtc caagttttct
    15001 tctagtttat tttgttcacc ttgcaatttg ctcatatagt ccgaaaaatt taagcttgct
    15061 atgagaaact ccgcttgttc tccaaaagta tcataaaaat gctcataata ttctaaactt
    15121 ttatcactat attctctacg ttcagaggtt tcttttgtta tattcttaaa aatcgatagt
    15181 tcttcacgtt ttaacttttt caatcgaatg ccaaaggttt cagccttttt caccaagggt
    15241 ttaccctttt tgctaaaact tttaagcaaa ctcttttcag ttaattcagt taaatcttta
    15301 tagtataacc aatctggttc tccacctggg taacctgttg ttaagccatc aaattgataa
    15361 cctaaatcag tcaaaccttg aataatactt tttttctcag catctattgg attaccttgg
    15421 ctatcaaaag tttgataagt ttcataaggt tttacaagca actctaatac accattttgc
    15481 ttggcatatt cttttaactc tgcataaaaa actggaagag catcttgttg ggtataaatc
    15541 ggccccgaat tgagttccat atgcagacca cccagcatgg gcaagctata aaccagagct
    15601 gcaacttgaa tttctccttc ttgtttcaaa gcaagataaa caattcgagc ccctcttttt
    15661 tctagcaaat cccccatctg gacagattgc ataaaggaac gagaagaaac ctgatcagaa
    15721 taagtctgaa actcttcttt cgtgagtgtt gttagtgcca tatacttact ttctatgttt
    15781 ttttcttaat gttttacgga aatcaagagc aagtcttaac agaggataga gaggatgagt
    15841 gggcattgta aattcaccca agtattcttc aatcgttgga ttaaattttt ccttaaaatg
    15901 ataaagtcca ccattgagag agttttcaac accacctaaa ttttgccaga ccatacctcg
    15961 ctcaaaggca tagcgagccg tttcatacca tgttaaaatt ggtgcattgt aacgtttaaa
    16021 atcatcatcc ataccagcat atatattgac agaggtagta ccaaattcca aactcaaagt
    16081 agccgctaaa ggaactctcg cttgacctac atctatatat tcctgcaaga aggtcaattc
    16141 ctctaacaaa cgttcttttt ccttcttctg cgcttctact tttgaagttc gagtcgactc
    16201 agtaaaggtc tcttccaagg ctctattttt cgctaactgt tcttctaatt cttgcgaacg
    16261 tttagaaaca tccaaggtgg ccaaggtgat ataggccttg tccttaaaat tatctaacaa
    16321 ttttttataa taggcttcat tcctcaaatg aatctctttt cgcttctcag tttttttcat
    16381 caactccgaa aatgaatcta atagttccag tccaccatat tgaatctcaa gccctttgtt
    16441 tcgtgctgtt cgaatagcct gttttgttga cttggaaagt ttatcttctt caaaattttc
    16501 cttgtatatt ttcgcctgaa tacgaggttg aatggtgtct cccatttcct ccgtttttcc
    16561 tgaccacctt actcccattt gttgcaaact atcaataata gccagatttt caggaaattc
    16621 tgtcttttcc tgattgatta aactttgaga taggcaaata cttgggtcaa aagtcacaaa
    16681 aaccgctctc ttactgcgag cataggactt aatagactga atggcaaaat tcaagagttc
    16741 tttatcccca taatccaata taggtcctct tgggatgtaa aacattttat agcctagcgg
    16801 aagagttcta atcaaaatac tagctgtcgc cagtaatttt tcttccctgt aaacaccaaa
    16861 cttctcatgt tgccaattag acttaacttc ctcccaagca ctactttgta atacattggc
    16921 taattcatgt tctttgacaa actgatcata ttctaatgtg ggaatgccaa tttgataacg
    16981 gtacatttcc tactctcttt cctccagtat tttattacta ttctactact ttcgtttgaa
    17041 aagtctagtg aaaacatatt ttattttagt tctactcccc ctatgctgaa gttcaaacta
    17101 agtcagtctc tcttctaatt tgaaatcaat tggtagggtt gttaaaaaaa cttccaattg
    17161 tttttcccag tagtaccact cgtgagttcc agcactatgg ctataggtca catcaaaacc
    17221 tagttttttg agatttttca ctgcgagatt attggcttcg tacaagaaat cctgttcgcc
    17281 acaccacgcc caaagtttgg tctttttatc cgatttttta gccagacttt caagagaata
    17341 gggactagtt gtccagtctc taatctctcc aaaaacacct ctccagtagg ctggacttcc
    17401 cagattttga ctttcaggag aaaagttttg aaagctgagg gcacctgaaa aactagctgc
    17461 atgagaaaaa cgatttgtcg taagagccag tttgaagcag ccgtagcctc ccatagaaag
    17521 accagcgata aaggtctttt cacgcttgct agtcatatta gggaagaagc gtttcagaac
    17581 ctgcggcaat tcctctgcta gagccgtgta gtagtcaaaa ccatactggg tatcggtgta
    17641 ccaaccattg ctggtattgg gcataacaac gatgagatta gttcctcgaa gcaagcgttc
    17701 tacattggtc cgcttaagcc aactattatg atttccagac atcccgtgca aaaggtacaa
    17761 gacgggaata tcttcacact ctggttcttc cactcgattg gcatcagggt agaggacatt
    17821 caccccccac tccatatcca atacttgtga gtaatactcg attttcatta ctgccatgat
    17881 tttctccttc tatttttcta taagaaaaag ccgaaactcg actttctctc tgtttatttc
    17941 aacgattatt ttgcttccat gactactggt aaaatagctg gacgacgctt ggtttggtca
    18001 aagagatact tggtcaaatt atctcgaacc ttccctttaa gatctgccca gtcaaagtca
    18061 tctccttgaa gataatcttc taccgtttgg ttaatcaatt ctgaactttc acggagaata
    18121 tcgcgactct tcttgagata aacaaatcca cgcgtgtgaa cacgagccct agccacaatt
    18181 ttcttctcac gacggttgac tgtaatagcc acgatgaaaa ttccatcctc tgacaagacc
    18241 ttacggtcac gaagaacaac atttccaaca tcaccaatgg cattcccatc aatcaagata
    18301 tctcctgctg aaaccgatcc agctggaaca aagtctccat tctcgtaagc catggtcgtc
    18361 ccctttttag gaatgaaaat gcgttctggc aacatcccaa ctgccatggc agccttagcg
    18421 tgagcatcca actcacgata ctccccttgg acagggaaga ggtacttagg ttgcaaaaga
    18481 ttgatcatca gctgcaaatc acgcacattt ccgtgccctg atacatgtaa actttgggta
    18541 atcaatttga caaccccacc tgcctgataa atcatatttt ccacacgcgc aacaaaggct
    18601 tctttagcaa tagacggagc cgtagcaata tagaccaggt ccccatcctt gatttctaca
    18661 taacgatggc gaccaatcga catcttacga agtccattga taggttcacc catacgacct
    18721 gtctcaagaa taatcaactc atggtcttca aagcgagaca tatctttagg cttaatcaag
    18781 agaatttcgt tggctaaaga caacttctta agacgaatcg ctgtgcggac gatattttca
    18841 atatcaaatc ctgtcaagac gatacgtcga cctgttttat ccgcagcgtc aaaaatctgc
    18901 tgaatacgag aaagattact ggaaacagct gcaacgatga tacgaccttc ccagtcagca
    18961 atagtttggg taatttcatc cctaacttca ctttcactag ccacctgaat attgctgtct
    19021 gcattggccg aatcactgag gagagccagg acgccgtcac gaccaatctc tgccaaacga
    19081 gcaaaatcag ttgcataaga ttcactagcc gtttggtcaa atttgaagtc acctgtataa
    19141 acgatgcttc cttccgatgt cttcaagaca attcccagac tctctggaac ggagtaagtc
    19201 gtagggaaga aggaaaccac tgtcccacca aaatcaatct ccgtattctc atcaatgaca
    19261 tggaaatcat taaatttctt aacggcatca tttcctttga caaagagctt tgccaactca
    19321 atggtcaact cagacccaaa tacaggaact ttagcctctg ccaagagata aggtagagca
    19381 ccaatggcat ccgcatgccc gtgggtcaag aaaaccccag caatacggtc gctattttca
    19441 aaaaggtaat ccatgtttgg aatcaccaca tcgaccccta attgttcatt ttcaggatat
    19501 tttaacccta cattcaaaac aaaaatggac tctccaattt cagcaatgta catatttttt
    19561 ccattctcac gcacaccacc aagtgttgtt aaactgatat tactcatttt tcctccaaaa
    19621 tcttagttta tcttgattat agggcaattc taccctctta ttctaaaagt tctgatactt
    19681 tcagccgaat cttttcctac cattatacca tttttttgat gattttcaaa atgaaggtct
    19741 gttttcaaaa aagagttgat ttcccaactc tttcctaact tctactcttt ttccatcaaa
    19801 aaatcataaa tttcttgcac cgtacccagc gccatcattt cttggtcttt aacggtttgt
    19861 ttgagatttt ggtaaatttg actttctcct atctcccgct ttggcgcctc tttattgact
    19921 gtcatcacac catcttttat cgtcacaaag cctagttctt caaatacttg aatcatcttg
    19981 accagcaaga tttgttgaat attaagatat gcagccaaat ctttcagctt gtagcgaata
    20041 tcaaactctg ggaactggta aatagtcttg tacaatttag caaactgatc tctagtccca
    20101 taacctgtca gataataggt cttgtcaata tcatttttga aatagacagc agagaaatgc
    20161 tgttcctgaa aaatggtctt cagctgagta atatcctctg gaatgttttt tacgacaaca
    20221 gcttcactag ccgcaagatt tggcagttct ccaggaaaat ccaagactgg aacaccttct
    20281 ggcaagactg cattttttcc acgaatgtta aaaagttgaa caccttccac tcgcgcatcc
    20341 accatcatca actggagggc agtttggcca ttccattggt tgacagacaa tttaaccgct
    20401 aactctagat tcttggtttg agaaaactct gtcgcccatc tgccttgacc aaaggctacc
    20461 acttcaaaac tcgcctcacc cttggaaatt ttcagcttta gatgggcatt acctgccccc
    20521 atagtacgag cactttcgac ctgaaaattc ttgatataaa aaataggttt ctgattatcc
    20581 attccaaaag gagctaaacg ttcaaaactt ttgaccgttt ccaagctaag tgcctccaaa
    20641 tccaactctt catctaggtt taacttattc ttgccaccag catctgcacc tttttcacga
    20701 acataatctt ccaaaacctg agataaatct gagagttgct caacttccag cgtcataccc
    20761 gctgcacctg catgacctcc aaaggcgatg aagaggtctc gatggggatc cagagcttca
    20821 aaaatatcga ccgcttccac actacgagca ctgcccttgg cacgaccgtc ttctatatta
    20881 agaacaatga ctgtctgtcc caattcttcc aataaacgac cagccacgat tcctagaacc
    20941 ccaggattcc agccttcctt ggccaagacc tgaaccttct tctcaggatc caccatggtc
    21001 ttggcttctt catagataga ctgaacgatt tccttgcgct cttcgttttt ctggtgaatc
    21061 ataagggcaa tctcatgcgc ttcctcatca tcaaatccag tcaacaaatc aatggcagga
    21121 ttgggatcat ccaagcgacc caaggcattc aaacgaggag caatctggaa accaaccgtt
    21181 tcttctgtta cttcgttggc agcaatccca gccatgtcca gcatttcttg cagaccaatg
    21241 cgctgggtat gacccaacat ttccagacca tattgaacta agatacgatt ttcatccgtc
    21301 agactcacca tatctgcaat agttccaata gcgaccaaat caagcaattc cacttgcact
    21361 tcttctaaca gggcacaagc caacttgaaa gcaactccac aaccagccaa atatttaaaa
    21421 ggataatccg catctggatg ttcaggatgg acaatagcat aagcatctgg cagggtttca
    21481 ggcatggaat gatggtctgt cacaatgaca tctactccca tagactgagc caatgcaata
    21541 gcctcatgac cagcaacccc attgtccacc gtcacaatca aggaaattcc ttcttgctcg
    21601 ataaagtatt tataaacact agcattaggg ccatagccat cggtaaaacg atttggcagg
    21661 taaactcggc actcagcacc aagttgttcc aaactttcct tcacaataga agccgaagtc
    21721 atgccatccg catcatagtc tccataaacg agaatatttt ccccttcttc aatagcctga
    21781 cgaatccgct ccactgcctt gtccatatca tggagcagat aagcatcatg taagtcctcc
    21841 aaggaaggtt ctaaaaactt cttcagactt tcttggtcct gaatccctct ctcaaacaat
    21901 aaccgagcca cctcaggacc cagtccagcc ttcttggcta tctttgtaaa atccgcatct
    21961 tctacctgca gggcaaactg ccattcataa gtaggtgtta tcaaaaagac atccactctt
    22021 tctaagaatt ctattgcttc attataacat gatttagacg ttttctctat ccagattgct
    22081 tttttataac attttatagt atattgaaac tagaatagta cacctctact tctaaaatat
    22141 tgttagaaat cgatttgact gtcccgatcg atttttcctg ttcttatttc actatagtga
    22201 attttttcag atatgatttg acaagaacat tcttttattg cagaatcgtg ttataaaatc
    22261 taacataaag gagttctctc atggttttag tagaatttaa aaacgtcgaa aaatattacg
    22321 gagactacca cgcactccgc aacatcaatc tccgttttga aaaaggacaa gttgttgtcc
    22381 tgcttggacc ttctggctct gggaagtcca ctcttatccg tacgatcaat ggtttagagg
    22441 ctgttgacaa aggaagtctc ctagtcaatg ggcaccaagt tgctggtgcc agccagaaag
    22501 atttggtacc tcttcgcaag gaagtcggca tggtttttca acattttaac ctttatccac
    22561 acaaaacagt gttagaaaac gtgacacttg cgcccattaa agttctagga attgataaaa
    22621 aagaagctga aaaaaccgcc aaaaaatatc tggaatttgt aaatatgtgg gacaagaaag
    22681 attcctatcc cgccatgcta tctggtggac aaaaacagcg gatcgccatc gctcgtggtc
    22741 ttgctatgca tccggaactc ctcctctttg atgaaccaac atctgctctt gatcctgaga
    22801 ctatcggaga tgttctagca gttatgcaga aactggcgcg tgataggatg aacatgatca
    22861 tcgttaccca cgaaatgggc tttgctcgag aggttgcgga ccgcattatc tttatggccg
    22921 acggagaagt tttagtagat acgacagatg tcgataactt ttttgacaat ccaagcgaac
    22981 ctcgtgccca acaattcctc agcaaaatta tcaaccacga aagtgacaaa gtcaaataag
    23041 gaggcgccta tgaaaaaaaa ttctttttat cagcattatt gattagcctt ttcggccttg
    23101 ctgctgccaa accagtccag gctgatacaa gtatcgcaga cattcaaaaa agaggcgaac
    23161 tggttgtcgg tgtcaaacaa gacgttccca attttggtta caaagatccc aagaccggta
    23221 cttattctgg tatcgaaacc gacttggcca agatggtagc tgatgaactc aaggtcaaga
    23281 ttcgctatgt gccggttaca gcacaaaccc gcggccccct tctagacaat gaacaggtcg
    23341 atatggatat cgcgaccttt accatcacgg acgaacgcaa aaaactctac aactttacca
    23401 gtccctacta cacagacgct tctggatttt tggtcaataa atctgccaaa atcaaaaaga
    23461 ttgaggacct aaacggcaaa accatcggag tcgcccaagg ttctatcacc caacgcctaa
    23521 ttactgaact gggtaaaaag aaaggtctga agtttaaatt cgtcgaactt ggttcctacc
    23581 cagaattgat tacttccctg cacgctcatc gtatcgatgc cttttccgtt gaccgctcta
    23641 ttctatctgg ctacactaat aaacggacag cactactaga tgatagtttc aagccatctg
    23701 actacggtat tgttaccaag aaatcaaata cagagctcaa cgactatctt gataacttgg
    23761 ttactaaatg gagcaaggat ggtagtttgc agaaacttta tgaccgttac aagctcaaac
    23821 catctagtca taccgcagat taaggaggat accctatgac agatttatca tcttggacag
    23881 cctattttca ggattttgga caatttttca atggtttcct ctttactctt gccctagcga
    23941 ttggatcctt tatcctcgcc atggtcttag gaatcttctt tggtgccatg tcaaccagta
    24001 aacgtccaat tttacgcatt ttagctcgca tctttgtgga attttaccaa aatactcctc
    24061 tcttggtgca gtttgttatt gttttttatg gcctacctct tatcagtgac catatcatca
    24121 tgattccaat ttattggaca gccgttctct gcgtgggact ctatcacggc gcttatatcg
    24181 ctgaggttat tcgttcaggg attcagtcta ttcctagtgg tcagatggag gccgccttgt
    24241 cgcaaggttt tacctatatc agtgccatgc gcttgattac cttgcctcag accttccgca
    24301 tcattctccc tccattgacc aaccaaattg ttaacctcat caagaacacc tctactgtag
    24361 ctatcatctc tggagtagac ttgatgtttg tgactaagtc ttggtcggct ctcaacggaa
    24421 actatatccc agccttttta ggtgctactc ttctctactt tgccctatgc ttccctgttg
    24481 cccagtttgg tcgcaagatg gagcaagcca acaaaaaagc ctattcactt taggaggtta
    24541 ctatggaatc tattttagaa gttttaaccc cagataacct agtctttatc tttaaaggat
    24601 ttggcttgac cctctatatt tctctgattg ccatcatcct ctctactatc atcggtacgg
    24661 tgctagctgt catgagaaat ggcaaaaatc ctgtcttgcg aatcatctcc agcatttata
    24721 tcgaatttgt gcgcaacgtt cccaaccttc tctggatttt tactatcttt ttggtgttca
    24781 aaatgaaatc cacaccagca ggtattacag cctttactct ctttacatca gcagccttgg
    24841 ctgagattat tcgaggcggt ctcaatgccg tagacaaggg acaatacgaa gcaggaatgt
    24901 cacaaggctt cacctcagcc caaatcctct actacatcat tctcccacaa gccatccgca
    24961 aaatgctacc agccatcatt tctcagtttg ttaccgtgat taaggatacc agcctcctct
    25021 actctgttat cgccctacaa gaactctttg gagccagcca aattctcatg ggccgttatt
    25081 tcgaaccaga gcaggtcttc agtctttgca tcctgattgc cctcatctac ttcagcttta
    25141 acctagcaat ttctagcctg tctcatatgc tagccaaacg ttggcaacaa gctgcagaat
    25201 aatactcttc gaaaatctct tcaaaccacg ttagctctat ctgcaacctc aaaacagtgt
    25261 tttgagcaac ttgcggctag cttcctagtt tgctctttga ttttcattga gtataaacag
    25321 ccactctcca gttcaattgg agagtttttt gatgagagta gatatttata gacctcaatt
    25381 tgacaccata cattttctat gataaaatgt aacaaattta tttacaacaa atcgaaatct
    25441 aaatgaaatg gaattttcta tgaaatcagt caaaggacta ctctttatca tagctagttt
    25501 tatcttgact cttttgactt ggatgaacac ttctccccaa ttcatgattc caggactagc
    25561 tttaacaagc ctatctctga cttttatcct agccactcgt ctcccactac tagaaagctg
    25621 gtttcacagt ttggagaagg tctacaccgt ccacaaattc acagcctttc tctcaatcat
    25681 cctactaatc tttcataact ttagtatggg cggtttgtgg ggctctcgct tagctgctca
    25741 atttggcaat cttgccatct atatctttgc cagcatcatc cttgtcgcct atttaggcaa
    25801 atacatccaa tacgaagctt ggcgatggat tcaccgcctg gtttacctag cctatatttt
    25861 aggactcttt cacatctaca tgataatggg caatcgtctc cttacattta atcttctaag
    25921 ttttcttgtt agtagctatg cccttttagg cttactagct ggtttttata tcatttttct
    25981 atatcaaaag atttccttcc cctatctagg gaaaattacc catctcaaac gcttaaatca
    26041 cgatactaga gaaattcaaa tccatcttag cagacctttc aactatcaat caggacaatt
    26101 tgcctttcta aagattttcc aagaaggctt tgaaagtgct ccgcatccct tttctatctc
    26161 aggaggtcat ggtcaaactc tttactttac tgttaaaaat tcaggcgacc ataccaagaa
    26221 tatctatgat aatcttcaag ccggcagcaa agtaacccta gacagagctt acggacacat
    26281 gatcatagaa gaaggacgag aaaatcaggt ttggattgct ggaggtattg ggatcacccc
    26341 cttcatctct tacatccgtg aacatcctat tttagataaa caggttcact tctactatag
    26401 cttccgtgga gatgaaaatg cagtctacct agatttactc cgtaactatg ctcagaaaaa
    26461 tcctaatttt gaactccatc taatcgacag tacaaaagac ggctatctta attttgaaca
    26521 aaaagaagtg cccgaacatg caaccgtcta tatgtgtggt cctatttcta tgatgaaggc
    26581 acttgccaaa cagattaaga aacaaaatcc aaaaacagag cttatttacg aaggattcaa
    26641 gttcaaataa gtaatcatac tctcctggga tttcccagga gagtttttta tagccaaatg
    26701 aaataagaca ggaacgatgg aattttggca ttcaaatcaa ttgataagaa tgttttatag
    26761 tggagtgaaa taggatacga acaaattgat taggaaaatc aaatgaattt atagaaatct
    26821 tttagcagtt atgttgtcct attctagttt caaaacgcta tagaagcagc attgtgctag
    26881 tctagattca gtttactata ctaaaacgag tagcttgaaa tcaaaaaacc caccctcaca
    26941 ggcaggtttt atctgtatta ttcagctaga ttatgcttta ccttctgaac cgaatacgtc
    27001 gatacgttct tcaaccgatg cttggatagc ttttacaccg tcagccaaga atttacgtgg
    27061 gtcgaagagt tttttcttgt cgtattctgc ttcgtttgct tcgtagtcac gagcaaattt
    27121 acgagttgcg ttagcgaatg cgatttggca ttctgtgtta acgttaactt tggcaacacc
    27181 aagtttgata gctgcttgga tttgctcatc aggaatacct gatccaccgt gcaatacgat
    27241 tgggaatcct ggaagagctt ctgtcaattt ttgcaagtgg tcaaggtcta gaccttccca
    27301 gtttactggg taagggccgt ggatgttacc gataccagct gccaagaagt cgataccagt
    27361 ttcaaccatt gctttagcgt cttcgattgg agccaattca cctttaccga tgattccgtc
    27421 ttcttcacca ccgatagtac caacttcagc ttctactgag atacctttag cgtgtgcttt
    27481 ttcaacaact tctttagcca atttaaggtt ttcttcaact ggaaggtgtg aaccgtcaaa
    27541 catgattgaa gtataaccaa cttcgataca ctcaagtgca tcttcgtagt gaccgtggtc
    27601 aaggtggata gctactggta cagtgatacc cattgattca acaaggttag cgatcaagtt
    27661 gcgagcaact ttgtaaccac ccatgtattt agcagcaccc attgaagttt ggatcaaaac
    27721 tggagctttt ttagcttctg ctgcgcgcaa gatagcttga gtccactcaa ggttgtttgt
    27781 gttaaatcca ccaactgcat aaccgttgtc acgggctgct tggacaaatt tttctgctga
    27841 aacgattgcc attttatcag gcctcctgta tatttttatg ggtcatccca tttacattgt
    27901 tcattttatc actttttgcc aaaaaaatct agtttttccc gcagtttcga ttgattttct
    27961 tctaactcca tctatgtaaa ccctttctcc ctagtcttgg acgacttttg gaaaatctat
    28021 aaagaaggtt aaacgattct cctccatctc gaaacgataa gctaattttt catgttctaa
    28081 tagactctta accacaaaga gccccatacc agaccccttg accttgcgac tagcattgtc
    28141 agaaaaagac tgggctagtt tttcttgttc ctctgagcta cagctatttt cgataaaaag
    28201 ttctccttct ctttctccaa ttcgaactaa gccacctgga acagagtgct taatggcatt
    28261 gctgatgaga ttagaaagaa tcaacttcat aactgatggg tttagataag cctgctgatg
    28321 ggtcaaacta ttgtctatct ggagctctct ttcctttgct agcaaggcat aatctttgac
    28381 cagattttgc gtcatctgga ggaggtcaat tgtttcccta tcatctcgca attcctgcac
    28441 agaagagagg gaaagtatct gcagaacatg gtgattgagt tcatccacaa tccccaaggc
    28501 aactcccaga tactggtctc tatccttata acgaccgata ttctctctca tattttcgat
    28561 taggattttc aaactagcca gcggtgtttt caattcatga gaagctcctc gtaggaattc
    28621 gaccttcatc ttctccagct ggagaatggc ttcattcttt tcatgcaagt ccgcaataac
    28681 agtcaagaga tgctggtaga ggctattgat ttgttccttg agattaccta tctcatcctt
    28741 agaatccacg cgcaatcgca cttgggaatc caggtccatc atccgacggg tcacccgctt
    28801 gatttccaaa atcggtgcaa caatagtccg agcgtagatg taggccacca agagggaaat
    28861 cagaaaggag gccagcaagg tatagggaag aaactggaga ctgatttgct ccgcttcctt
    28921 ttgtaaatcc atggaagcta gaaactggag aatcatagta ccaccgtctt gcgttttcac
    28981 ctcgcgctcc tcaataaaga gagaggttgt ctggcggtct gtgtccagag gaagactgtc
    29041 cttgacttct aacttgtcct cggtcatctc acctttgacg gtccccttga tatcactagt
    29101 ctgggaatac aagtctaaca cttgctcgat actctgccta tctttccctt ctagggactg
    29161 ggcaatggct gttgcctttt gaccaatggt ttcctgacga tgactcagat aagtcgaagg
    29221 aaaaagaaaa taaatagcta aatgaaggca gataaccaga acactaaata tcgagaaggt
    29281 atagataaat atctttgcaa ataaacctgt tcgtttcatt ttcgctccaa tttataacca
    29341 acattgcgca cagtgaggat acaatccaag tctagctttt tccgcaattc cttgatataa
    29401 acatcaataa cacggtcaaa gggaacctca tctgtcgctt tccagacggc atcgataatc
    29461 tgagatcgag tcaaggcccg gccttcattt ttcactagat agtccagaat ttccaactct
    29521 ttggcattga taggcacttc ttgacctgcg aggcttgcac tgtagctttc aaagtccacc
    29581 ttggtatcct tgtaagaaaa gattcgtcct gtatcgtagt agcgcttgaa aatcgcgtcc
    29641 accctcactt ttaaaaggga gagggagaaa ggtttttcca gatagccatc tgccaaagag
    29701 gcaaaggcac tcatcttgta ttcctcatct tgaaaagctg tcaacatcaa gacaggaacc
    29761 tgactggttt tacgaatctc agctaggact tctaagccgt tgagcttggg catctggata
    29821 tccagtaaaa ccagggccac ctcatagcta gaaaattgct ccagagcttc ctgaccgtcc
    29881 gctgcctcaa tagtttcata gccacaatcc gtcaaataat cactgacccc ctcacggatc
    29941 atctcttcat cttctacaat taaaattttc atactttaac tgctctctat tttttatttt
    30001 tcttagaata aatacctacc ctattttcta ttatagtctc ttgctggcct tttgtctgca
    30061 agcaactgac cactagataa aacgttgtga aattcctttc tcataaattc cataacttta
    30121 gtatattata tttaagcact aaagtacaaa gaaagcaact gaaagcaatg attttcacca
    30181 ctgctttcgg atttattttg aattgttaaa tagccattcc tatccactat tcttgaatag
    30241 aaacacaaga tgcaatcttt attctagact cattttttca aatttattca ccatccagca
    30301 agagctcttt tggttgtttt ctaaggagat tgcttgaagc aagcgccata acgagaacca
    30361 ctagaaccaa ggcaaggaca aaaatgatga taaagtctga tgtctgaatg gaaatgtcta
    30421 ggctcgacaa ggtcttgcta aagccatcta cttctgcacc accaccaagg ttagaggctt
    30481 gagccgcctt actagcctgt ttggcaacac ctgaagtcac attggcaagg acagtgtttc
    30541 caattgcacg ggcagtgtaa ttagctagga agtaagcaga aactagagca gggatagcaa
    30601 tcaagataga ttcggtgatg aattgaccca agatacttgc ctgcttgagg ccgatagaga
    30661 ggagaattcc cacttccttg cgacgggcgt tgatccaaag gctgagcaag agggcaagga
    30721 ggagaactga gaagctcaag ctaccccaga agaggaggtt ggccatcttg tacataccag
    30781 agatagattg ctcaagagct gggtagttag aggagctctt gacgagtgtg tagctcttcc
    30841 agttgatacc actgatgcca ttcaactctt tcataacatc atccaagttc ttgtctgctg
    30901 ttacaaagaa ggttgcgtcc ccataaatgg ctgtgtcttc tgtgtatcca taaagttttg
    30961 cagcagtgtg aatgtctgta atagctgtgt tttcgtaaag ttcttgtgag taggttactg
    31021 ctgacttatt atgaccatca aagagtccct tgattgtcac ttcaactgtt tccttggctc
    31081 ctttttcatt atctgcatcg tagatattag agtccagttt aaccttgtcc cctactttcc
    31141 agccgtgttt ggctgccaag tccttgtgca agaggatttt atccttgtcg tcgttggtta
    31201 agtgctctcc ttcgactagt ttataagaac cagagacaaa cttgtcttct ttagaggagt
    31261 cattgacacc tgtaatcatc aagctacttc caaaacgctt ggcacgatca gcagtgagat
    31321 tcttcttggt ttctggcgtt tcaatcaggt catatccagt caaatctccg atagcgttga
    31381 tacgtttgac ataagactca atggccttgt tttcggtgat ttttttgatg tcttcaccct
    31441 tgatattccc agcaccacga ggcgttcctt ggttgacgcg acgattgatt tgcatggaga
    31501 agctattggt gatattttta aaggtctcct gagaagcctt ggcagtagct cccttgattg
    31561 acaagccgac caaactcaag ctcgccatga ggagaataat caggaagatg acaatcgatt
    31621 tgaaaaactt ccttgtaaca taggcaaatg cgttgtgtaa catagattcc ctttctagat
    31681 tttgttttaa tcattctatt aaaataagct caaattattt actagtattg cgcgtttcag
    31741 tcagtttctt atcctttaat tcaagtgtaa tatctgacgc ttgtgccact tctttactgt
    31801 gagttacgac aatcacacat ttacctgttt tctgggcaag tgatttgagt agttcgacaa
    31861 tatctccagc agttttagga tccagatttc ctgttggctc atcagctaga ataactggag
    31921 cttctgagac caaactgcga gcaatggcaa cacgttgctg ttgaccacct gataactgga
    31981 gaacattccg cttgatctgg ctttcatcca aaccaagctc aagaagtgta ttcttgcttg
    32041 cctttttgtt gaccaatcgg atattttcca gcggagaaag ataatctatc aagttataat
    32101 tttgaaagac cagggaaata tggtgcatgc gatggtaaga atagcccttc ttacgaatat
    32161 cctctccttg aaaaaggata gaaccttcaa caggactatc tagaccagca agtagggaca
    32221 agagtgtgga ttttcctgct cctgactccc caataatact gtaaaatttt ccgggttcaa
    32281 aattataatt gatctgatat aggactgctt cagcagtatt cttataacgg taggtaacat
    32341 cttgtaattg taataaagtc atgatttctc cttcttaact aatagatgat aaaatttctt
    32401 tcggtgattt tctaaataag aataggaaac aaagggctac agataagcaa ctaagcagaa
    32461 ctagaaaaac ataggattct gcaaaagata agatgctagt tgataaactg cttgctttgg
    32521 ctagtgtatc ttgtaagctt gcctgatctc cacttgctag tagagtttgg agtaggtaag
    32581 ttgtgattgc gtttcctgca acaaatgctg gaagcaaagc tccaagagat accaaaacta
    32641 cctctaaaca gaattgtagg aagatcgagc tcttgccttt tccaagtgca agtaaaatcc
    32701 ccacttcata gacccgttct ctcaaccaga gagacaaaac cagaattaag gctccagctc
    32761 ctgctatcaa catcccataa aggaagatgg tcaggaaggt ttggaaagtt gcaactgagt
    32821 ctttgatttg ttcaaaagcc ttgttttcct tttcgacttg gtagccttga ttttccaagg
    32881 ccaagttttc tacctgcttc atgagtccgt ccatttcctt aggattttct acatagaagc
    32941 gtgctgcact gacttgagct tcactattgc ccaaaagggt ttggctactt tcatagtctg
    33001 taaagacttg attttcactg aagtcagaag acaagcctgt gaatttctct tgttttttac
    33061 cagaaaagat gccgataatc tcaaactcta ctgtttgtcc ttttccagat tcagactgac
    33121 cagcatccaa gccaatcttg tcatgaagcg aaagaccgtt cttcttagcc aattcttcgt
    33181 ggataaggat tttcttggaa tccccttttt gaaggtgtcg cccttctttt agattgaaag
    33241 ccgaactggt aaaggttaca tccttggatg aatcctcaag agccgttaag ctaaccaagt
    33301 tattgtctgc agctgataaa tcatcacgct ccacgctctg ctcgccagtc actgcttcct
    33361 tgtcttttag ttttgcgacc gtctcaagtt caggagagac attttccagc cccttaatct
    33421 tgcttacaga tgctaggtct gacaacttga atgtctgacc attctctatc ttcttaatag
    33481 aaaaagatgt attgagtgat ttataaagat tgctttctac tgttttgttg gacttcatca
    33541 gagtcaaaca ggctgaaatt ccggccaata agaccaataa aatcagaaat aaaataaaac
    33601 ttctcagtcg ctttctgctg acataagccc aagatctttg gattggattc atttgtcacc
    33661 tccatatttg taagactatt ataaaaccca aatatgaaat gtttatgaaa tacgaaaaaa
    33721 aaatatcgag taggggataa tctctagccc ctctcacacc acc
//
LOCUS       DAVIME010000022        32243 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVIME010000022 DAVIME010000000
VERSION     DAVIME010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.022"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(239..1327)
                     /locus_tag="VV588_001088"
     CDS             complement(239..1327)
                     /locus_tag="VV588_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU7083444.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALIGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTIKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(1345..2013)
                     /locus_tag="VV588_001089"
     CDS             complement(1345..2013)
                     /locus_tag="VV588_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU7083445.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(2032..4470)
                     /locus_tag="VV588_001090"
     CDS             complement(2032..4470)
                     /locus_tag="VV588_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU7083446.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPVTTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(4621..5919)
                     /locus_tag="VV588_001091"
     CDS             complement(4621..5919)
                     /locus_tag="VV588_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU7083447.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            complement(5936..6244)
                     /locus_tag="VV588_001092"
     CDS             complement(5936..6244)
                     /locus_tag="VV588_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7083448.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(6290..6610)
                     /locus_tag="VV588_001093"
     CDS             complement(6290..6610)
                     /locus_tag="VV588_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU7083449.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(6805..7785)
                     /locus_tag="VV588_001094"
     CDS             complement(6805..7785)
                     /locus_tag="VV588_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU7083450.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(7798..8544)
                     /locus_tag="VV588_001095"
     CDS             complement(7798..8544)
                     /locus_tag="VV588_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU7083451.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            8666..9442
                     /locus_tag="VV588_001096"
     CDS             8666..9442
                     /locus_tag="VV588_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU7083452.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            9517..9714
                     /locus_tag="VV588_001097"
     CDS             9517..9714
                     /locus_tag="VV588_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU7083453.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            9932..10528
                     /locus_tag="VV588_001098"
                     /pseudo
     CDS             9932..10528
                     /locus_tag="VV588_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            10604..11053
                     /locus_tag="VV588_001099"
     CDS             10604..11053
                     /locus_tag="VV588_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU7083454.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            11066..12157
                     /locus_tag="VV588_001100"
     CDS             11066..12157
                     /locus_tag="VV588_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083455.1"
                     /translation="MSEIEIINAKKIYHDVSVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNLSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            12147..13792
                     /locus_tag="VV588_001101"
                     /pseudo
     CDS             12147..13792
                     /locus_tag="VV588_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(13895..14587)
                     /locus_tag="VV588_001102"
     CDS             complement(13895..14587)
                     /locus_tag="VV588_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU7083456.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(14831..16168)
                     /locus_tag="VV588_001103"
     CDS             complement(14831..16168)
                     /locus_tag="VV588_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU7083457.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(16178..16444)
                     /locus_tag="VV588_001104"
     CDS             complement(16178..16444)
                     /locus_tag="VV588_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU7083458.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(16709..17095)
                     /gene="rplQ"
                     /locus_tag="VV588_001105"
     CDS             complement(16709..17095)
                     /gene="rplQ"
                     /locus_tag="VV588_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU7083459.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(17107..18042)
                     /locus_tag="VV588_001106"
     CDS             complement(17107..18042)
                     /locus_tag="VV588_001106"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU7083460.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(18085..18468)
                     /gene="rpsK"
                     /locus_tag="VV588_001107"
     CDS             complement(18085..18468)
                     /gene="rpsK"
                     /locus_tag="VV588_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU7083461.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(18486..18851)
                     /gene="rpsM"
                     /locus_tag="VV588_001108"
     CDS             complement(18486..18851)
                     /gene="rpsM"
                     /locus_tag="VV588_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU7083462.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(18869..18985)
                     /gene="rpmJ"
                     /locus_tag="VV588_001109"
     CDS             complement(18869..18985)
                     /gene="rpmJ"
                     /locus_tag="VV588_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU7083463.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(19010..19228)
                     /gene="infA"
                     /locus_tag="VV588_001110"
     CDS             complement(19010..19228)
                     /gene="infA"
                     /locus_tag="VV588_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU7083464.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(19345..19983)
                     /locus_tag="VV588_001111"
     CDS             complement(19345..19983)
                     /locus_tag="VV588_001111"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU7083465.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLT
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(20134..21444)
                     /gene="secY"
                     /locus_tag="VV588_001112"
     CDS             complement(20134..21444)
                     /gene="secY"
                     /locus_tag="VV588_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU7083466.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(21457..21897)
                     /gene="rplO"
                     /locus_tag="VV588_001113"
     CDS             complement(21457..21897)
                     /gene="rplO"
                     /locus_tag="VV588_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU7083467.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(22042..22266)
                     /gene="rpmD"
                     /locus_tag="VV588_001114"
     CDS             complement(22042..22266)
                     /gene="rpmD"
                     /locus_tag="VV588_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU7083468.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(22238..22732)
                     /gene="rpsE"
                     /locus_tag="VV588_001115"
     CDS             complement(22238..22732)
                     /gene="rpsE"
                     /locus_tag="VV588_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU7083469.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(22750..23106)
                     /gene="rplR"
                     /locus_tag="VV588_001116"
     CDS             complement(22750..23106)
                     /gene="rplR"
                     /locus_tag="VV588_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU7083470.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(23190..23726)
                     /gene="rplF"
                     /locus_tag="VV588_001117"
     CDS             complement(23190..23726)
                     /gene="rplF"
                     /locus_tag="VV588_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU7083471.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(23918..24316)
                     /gene="rpsH"
                     /locus_tag="VV588_001118"
     CDS             complement(23918..24316)
                     /gene="rpsH"
                     /locus_tag="VV588_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU7083472.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(24601..24870)
                     /gene="rpsN"
                     /locus_tag="VV588_001119"
     CDS             complement(24601..24870)
                     /gene="rpsN"
                     /locus_tag="VV588_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU7083473.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(24888..25430)
                     /gene="rplE"
                     /locus_tag="VV588_001120"
     CDS             complement(24888..25430)
                     /gene="rplE"
                     /locus_tag="VV588_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU7083474.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(25454..25759)
                     /gene="rplX"
                     /locus_tag="VV588_001121"
     CDS             complement(25454..25759)
                     /gene="rplX"
                     /locus_tag="VV588_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU7083475.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(25837..26205)
                     /gene="rplN"
                     /locus_tag="VV588_001122"
     CDS             complement(25837..26205)
                     /gene="rplN"
                     /locus_tag="VV588_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU7083476.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(26231..26491)
                     /gene="rpsQ"
                     /locus_tag="VV588_001123"
     CDS             complement(26231..26491)
                     /gene="rpsQ"
                     /locus_tag="VV588_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU7083477.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(26516..26722)
                     /locus_tag="VV588_001124"
     CDS             complement(26516..26722)
                     /locus_tag="VV588_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU7083478.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(26732..27145)
                     /gene="rplP"
                     /locus_tag="VV588_001125"
     CDS             complement(26732..27145)
                     /gene="rplP"
                     /locus_tag="VV588_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU7083479.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(27149..27802)
                     /gene="rpsC"
                     /locus_tag="VV588_001126"
     CDS             complement(27149..27802)
                     /gene="rpsC"
                     /locus_tag="VV588_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU7083480.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(27815..28159)
                     /gene="rplV"
                     /locus_tag="VV588_001127"
     CDS             complement(27815..28159)
                     /gene="rplV"
                     /locus_tag="VV588_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU7083481.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(28171..28452)
                     /gene="rpsS"
                     /locus_tag="VV588_001128"
     CDS             complement(28171..28452)
                     /gene="rpsS"
                     /locus_tag="VV588_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU7083482.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(28556..29389)
                     /gene="rplB"
                     /locus_tag="VV588_001129"
     CDS             complement(28556..29389)
                     /gene="rplB"
                     /locus_tag="VV588_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU7083483.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(29407..29703)
                     /locus_tag="VV588_001130"
     CDS             complement(29407..29703)
                     /locus_tag="VV588_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU7083484.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(29703..30326)
                     /gene="rplD"
                     /locus_tag="VV588_001131"
     CDS             complement(29703..30326)
                     /gene="rplD"
                     /locus_tag="VV588_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU7083485.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKLVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(30351..30977)
                     /gene="rplC"
                     /locus_tag="VV588_001132"
     CDS             complement(30351..30977)
                     /gene="rplC"
                     /locus_tag="VV588_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU7083486.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(31194..31502)
                     /gene="rpsJ"
                     /locus_tag="VV588_001133"
     CDS             complement(31194..31502)
                     /gene="rpsJ"
                     /locus_tag="VV588_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU7083487.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(31768..>32243)
                     /locus_tag="VV588_001134"
     CDS             complement(31768..>32243)
                     /locus_tag="VV588_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU7083488.1"
                     /translation="NLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDIL
                     ALQAGMDVLTIEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELK
                     RRLARDTTVRNRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
BASE COUNT         9644 a         6862 c         5510 g        10227 t
ORIGIN      
        1 ataattgggg ctaattaatg tattcacaat aaatagccga caacctatgt cgctttttga
       61 tttatgaaga acgtatagta gactgaatct gaaatagtac gaaacaattg ctaaaacact
      121 tatagaaatt aattttactt tcccaatcga tttgttctca tcttatttca atctgctata
      181 gaattcaata cgaggatcaa taaaagacta ccatttggaa aacagtagtc cttattgttt
      241 attttgaatt tacataggca tctacagcga taatagcttg agcaacatct gaaggcgaaa
      301 tcttaaacgg catctgatga attgtctcac cctccatagt tgcttgttta ccaactttta
      361 ttaaatcatc atatccaact tgatccaaat gcatttcttt tatagttgtt ggcataccaa
      421 tttttttgta aaactcaata tacttatcaa gttcttcttt aggtctattt tccaataata
      481 gttgtactaa agttccataa gctacttttt caccatgtgt taaatgatga atgtcaccta
      541 tcaatgcagt aaaaccatta tgaattgcat gcgccgcagc taatcctcca ctttcaaaac
      601 ctagaccact caataaagta ttagcttcaa caatattttc taatgctggt gtcaccactt
      661 tagcttcaca agctgccata gcctgtaaac catctgcaaa cagcgtttct tcacatttct
      721 tcgcaattgc aactccagcc aatgtttgct gttgtcccaa catagttttt ccatttgcct
      781 gcataaccgc acgcgcctca acccaagttg ctaaaccatc tgcaatacca gacgctaata
      841 aacgcttagg ggcttgtgaa ataacttttg tatcaaccaa aactaaatct ggatttttag
      901 aataaaatag ataatgatca aatgcacctt catctgtata aataacagat aaagcagata
      961 caggtgcgtc ggtcgatgca attgttggag caataataac aggcttttca atcaaatctg
     1021 caatagcttt tgcgctatca atcgtctttc ccccaccaag accgataata ctatcacaat
     1081 tttctttctc agccaaggca acaactcgat tgatttcatt gtcagaagct tcaccattaa
     1141 atagcgccag aacaatatgg aaaccatacc tatgtagata atcttcaaat cgttttccaa
     1201 caatatcata aaccaactga tcgcataata gaatagggca atttcccaaa tccaaaattg
     1261 atttggcatt ttcaaacaag gcattttccc cctgaatata tctagaagga ctagcaaaaa
     1321 ttctcatatg tatttcctct ctatctaaat ggaacgacta ttttgaataa caaaccaatc
     1381 gtcagaaaaa tcatcaaccg ccttttggat agatggcatg gcgaaagctg attcaaaaac
     1441 atccgctcct gctgtaacag catgcgcacc tgcagctaaa gcattattta cttgtgctac
     1501 atttttaaag gatgcagcta aaatcttact aggagagttc tgtctatcaa tagcaagagc
     1561 taattgacga atgacagaat ttgaatcaat gttcagattt tccattctat tataatatgg
     1621 agctaggtaa tccgctcctg cttcgatagc taataatccc tgaataactg tataaatagc
     1681 tgttgcagtg atatggtagc cctctttttt tagcgccttt attgcacgta atccagctgg
     1741 agtaacaggt actttgataa atatatcatc tcctgcttgt cttcgaattt tatgagcatc
     1801 ctttaagatg ccttcaaaat cttgagaaat cacctgaaca tgaatagagg gtgtagagcc
     1861 aatcaattct cttacatctt tgattcgttc aaaaaaatta atagaaccct ctctttttgc
     1921 aatagtggga tttgaagtta ccccagctag cggcaaaatt tcagaccact ttttaatctc
     1981 atctaaattt aatgtgtcaa gcataaattc cataaaaaga acctctttat tttacaaagt
     2041 atgctcagta cgtcctataa tgtcatcttg ggttgcctta gaaagaacat tgaagaatgc
     2101 agagtatcct gcaacacgaa caattaagtc tctgtgtttt tcaggatgtt tctgagcgtc
     2161 aatcagcgtc tctctggaaa caacattgta ttgaatatgg tacccatgta aacgattaaa
     2221 gaatgttcgt aacaaagcaa ttagttttaa tttatcttct tctttggcta acgtttgagg
     2281 atttactttc tgatttaaga gaaccccacc tacgatttca tctgttggta attttgaaac
     2341 agattttaaa acagatgtag ggccgtgttg atccatatta tgtgatggtg aacaaccctc
     2401 tgctaacggt gtacccgcgt tgcgtccatc tggagttgct aatgttccac gtccctgccc
     2461 tacgttggct gagatagaag atgttcctga ataacgaatt cctccaattg gacctcttcc
     2521 ataacgtgta ttaggatatt tagcaatttc atcaacataa atgtcataag cagcagtaac
     2581 caatttgtca gcataatcat catcattacc atacttaggt gcatcatgaa tcaacatttc
     2641 ttgaatgacc ttaccttctt ctccggcata atctgtttcc agtgcatgcc aaagctgact
     2701 tgggcttata cgttcttcct caaacaccaa ttttttaatt gcagctaatg aatccgacaa
     2761 atttgcaatt ccaacttgca atcctgatat ataatcatat actgctccac cttctttaag
     2821 gtgttttcca cgaccaatac aatcatcagt caatgctgaa catagaatat caggaacttc
     2881 tcgttccaat gataaatcaa tagaattttc aacaataaca ctcattcgtg tcaaatatct
     2941 tagtgtttta tcccaagcat tttctaattc agaaaagttc ttcatatcct taaaatgacc
     3001 aaagcttggt gcaaaccgtt tacccgaagc cggatcaatt ccatcattca tcgtgataag
     3061 tagaacctta gggaagttca tataactcat acctgtgcaa cgatagcccc atttccctgg
     3121 aactgccgtt tcaacacatc caatggcact gtaatcataa gcatcatctt ccaatactcc
     3181 ttttgcaata aaagaaggaa taataatctc atcattatta aatgcaggca taccaaaacc
     3241 aagtttcatc acttcaatac actcattcat gaaacgagca tctaaacctg catggtaacg
     3301 tacagttaga ttaggttgcg gtagatgggt ttgtgcaact gattttaata ccaaataaga
     3361 taatgggtta acagcatcct tcttatctcg agtctgtcca ccaattgtaa cattttgata
     3421 taaaggactt cctgctgaag aaaatgtatg tgattgactg cgaaccttat taattgtaat
     3481 tgtcttaatc caaagatttg tcagacgttc aacaatgcta tcttctgttt ctttaccact
     3541 ttctaaatca gccttcatat atggatacat atattgatca aaacggccat atgaaagaga
     3601 gtggccatta gattcaattt gtaaaataca ttgaataaac caaactgatt gaatagcttc
     3661 tgcaaaagta gttaccggtt catatgggac tctagagcaa atatctgcaa tctcaagtaa
     3721 ttctttctta cgtttaggat ttgcattttc ggctaaactt ttagcaagag caacaaagcg
     3781 ctttgcatat actttaatag catcgattac gataaatata gagtcgtaaa aatgatattt
     3841 atcaatactt gctggatctg ttaaatctag agctgctttt gctttacgag cccgctcttc
     3901 aaaacctctt aagccaaatt gcaaaagttt ctgatagtta actgctaggt gagcatctcc
     3961 agaattcatc ttaccttcca taccgaagaa tcctgtttcc atataaacag acacttcttc
     4021 aggtaataag gcaccagctc tagcacgtaa attattattt tcccaaaacg gagcaatact
     4081 tctaagttgt tcttttgttt cttctgtaat atagaaaaca tctccatcac gcttttcaaa
     4141 aagatccaac tcattgagaa caaattctag cgtatattcc ggaaaaatag gagcatcttt
     4201 attggaagaa gcttgatttc ccccaatcat agattcttct tcaatataga tagtcatatt
     4261 ttccaaaatt tctttcagca tatatgcacg ttttaggaca ttaggttgtt ccttgtatcg
     4321 ttcataggcg cgtgttgcta gaactgctct ctcagcatca atataaggtt ttttatttaa
     4381 aacatcttct cgatatttgt tcatcctttc agtaaggctg ccaaaatatt ctgtcttgat
     4441 tgttgttctt gctacttctg tatttaccat cgtaaccacc tttctttcga aaatattttt
     4501 atttctttcg aaaatataat accgattttt atagaaattt tcaagctttt aactagaaaa
     4561 attttaactc tctaattttt agcacaaatg tgtgagttta acagtaacac acaaatacct
     4621 ctaagattgt ttgatttcat tttggtaagc taaacgatcc tgtactttaa agaatggaaa
     4681 ataaaccaat gtagacatcg ctaatatcac cagctgagta ataactcctt gccatccacc
     4741 caccaaaaat cctgataaaa tagctggtgt actccaaggc aatgttaccc ctgagaatgg
     4801 ctgcatgaaa cctgttgcaa tagctccata tactatcaca gctgcaagta caggaacaag
     4861 aatgaaaggt acaaacataa ctggattcat gacaatcgga aatccaaata caactggctc
     4921 atttacgtta aatattgctg gaaaagcggc aacttttcct aaggcttggt attgttttga
     4981 ttttgctgca aaaagcatgg caactacaag accaaacgta atccctgaac ctgatagaat
     5041 taaaaatgaa tctaaaaatt gttgagtaac aatatgtgca ccattttcta atgatagatt
     5101 accagaggct aacatagctt tattagcatc aagattagat aaaagcagag ctgtcactac
     5161 tccatttact accgattgtc catgaacacc aaaccaccac aaaaatgata taaagaatgc
     5221 aattccaata gcaccataca aagatccagt taaaccttgc aatggaactt gaatagcaga
     5281 ataaatcatt tctatgaatg ttccgccatt agtcaatgac ttcgctaaaa tatatacaat
     5341 catagaaagt aagaaaatta caaatgctgg aatcattgct tcaaactgtt tggcaatagc
     5401 ttgtggaact tgttctggca tcttaataac aatttttctc tttataaaga aggtataaat
     5461 acttcctact accaaaccta taatgatagc accgataatt ccttgacctc caaaccaaac
     5521 tttactaata gcatccccaa ttgcctcacc ttgtttaggg atataagatg atcttagcaa
     5581 aataaagaat gcagatacag atagaactcc agctggtaaa gcctctactc cgctattctt
     5641 agcataagaa taggcaattg aaaaacaaga aattagaccc ataatagcaa aagttcctga
     5701 atatacttgc ataaacggct ctgtccaatt agctccaaaa acactagcaa tgctcttatt
     5761 taatccttcg aacggcaatt gtcccataat caagaataaa ctaccaacta ctgtcaatgg
     5821 caaaattgct aacatcccat cttttagagc tataatgcca cgcatattca caaacttcat
     5881 catcggtgca atgattttct gaacatccat ctttgccata ataaatctcc ttttcttacc
     5941 cactaatcaa agatagggcc aaatctaata cttttttccc atctaacata ccatagtcca
     6001 tcatcggaat aacagctatc ggaacatcac acttatcaca aatttctttt gatttatcta
     6061 atgtataagc aacttgtgga cccaatagtg caacatctat atttggcgca taatccgcta
     6121 atttagactg agaaaacgcc tctatttctg cctcaactcc actagcttgc gctgcaattt
     6181 tcatattatt tacaagcata ccagtagaaa aacctgctgc acaaaacaaa ccaatcttca
     6241 ccattatgtt ttcctcctct atgttaataa caatgataat actctagtat tattttttat
     6301 gaagttcttt tctcaaacta ataatttctt tgattaaatt aatctccgtc atactagtca
     6361 tgagatgatc ttgtgaatga acaaagagag ctgtaatttc tgtctttgta ccagacgctt
     6421 cctgtgccaa gaattttgtt tgtagattat gagcttctaa taaggctgca tcagctaact
     6481 ggatttcttc ttcacatcgt tcacatgtac cattttttat gtaatctaac gctttataaa
     6541 tatgttgttt cgcatcgcca gcatataaaa ttaaacccat gataatttga tctggaacaa
     6601 taatttccat aaattcctcc tcatttcact atgtaaaaag cttttttcat ttgaaatttt
     6661 aaaattttct tttgtaacta tagaatacaa ctacataata aagttgtcaa tccaaaaaca
     6721 acagataaac tatttttgtt tatataagca caaatgtgca atcaactaaa aagaaaaacg
     6781 ataaactgaa tcagtctatc attttcactc acctagaatc tctctaaaag tcaaatcccc
     6841 atcttcttcc aaaactttta aaattgtatt tttgtctgta atcaaatgat ttactaaatt
     6901 agcacgcaag acagaaagaa tcgaagatac tttcgtatca ccgtaagcaa cagctaaact
     6961 ttgaggaata ttttttaaat cttccaaaga gattgctatc gttctttcct gtaagttttc
     7021 atagacttct ttaccttttg aatcaaaaaa tcgacaacaa atttctccta cagttttaac
     7081 tttggtcaat tctttaaagt catcctctgt aagcatgtct aaccattgat gttttccttt
     7141 attgctaaaa tcaccaattc cgactacagc tatatctaaa tctttccaac tatttttcaa
     7201 attttcaaaa tatcttgatt gcaaaatacc atctgctaac aatttatttt cttgcacaat
     7261 cgttgcattc ataaatgtac actctccatg aaattttcta gacatttcat aaatcagtgt
     7321 attcacatgg tatttagcgt gtatgtgact aggaccacct gctagaggat agaagtgaac
     7381 atttcggaca cttttactgt gaattaaatc tactaaatta cttaaacttt tcccccaaga
     7441 aaagccaatt ttcatattat catcaattaa attcctaagg acacctgctg caacttgaga
     7501 aattctttca gataaaattg ttggattatc atcaaattca tttggaataa tttctaaact
     7561 ttccagacca tatttttctt ttacataatt ttccaactta aacatatttg tatcaaaatt
     7621 ctctatttca attttaacaa ttcctgcatt ccttgcttct gttaacattc tactaataga
     7681 ggttctataa attcctaatt ttgctgctat ttgtgactga tttaagtttt caatataata
     7741 cagataagca attttagaga gcagtttatt cctatcttga ttcatacact taacctctta
     7801 cgaaactacc ttaaccatta tcccagcatt ttctaatgta gctatatttt gtttagaaag
     7861 tttttcgtct gttattactt catagacttg acttaaagca aatcttctta ctgtacccct
     7921 tttatcaaat ttacttgagt cagttagtac aatgacttta tccgacgctg ctgaaatata
     7981 ttgaactacc tcactgcgca ttaaatcttt tcctgtaaag cccatctctt tatcgtaacc
     8041 atctgtccca acaaaagctt gatgcacatg aaaagtctgt atcatttctt ttaataaagg
     8101 tcccacagta acctgtgaat ccttctgaaa ctctccacca agaacaataa tacgacatga
     8161 atcataagct ctcacaaaat ttgctataaa aaatgaattt gttacaatcg taacatttct
     8221 tttttgcttg caaatttcct cagcaagtaa agcacaggtc gatccagatt ctatcattat
     8281 tgtttcatta tctgacacca attttactgc ttcctgaaca atttttctct taatttcata
     8341 attaattgac aaacgtacat ttaagtcatc tccactattt aatacagcat atccatgctc
     8401 tctgtgtaat aaaccttttg actctaattt atctaaatct tttctaatcg ttactttcga
     8461 tacatttaat ttttccgata atgtattaac gtcgatcttt tcatattctg atactaattt
     8521 aataatttgt tccaatcttt tcattttaca cctccgtttt attctaccaa aataaaaagc
     8581 aaaaaacaac aaatcaacct ttcgttcgta attgtttttc tttcgttttt gtgataggat
     8641 agacttatga agaggaggaa ctcttatgga aatatctaaa ggaattattt ttaatattca
     8701 acacttttca attcatgacg gcccgggtat tcgtacaact gtttttttaa aaggatgtcc
     8761 tctgcgctgt ccatggtgtt ctaatcctga atctcaaaga atgaaacctg aaaaaatgaa
     8821 agatgctcaa cgagagaaat tcaccttagt cggtgaagaa aagactgtag aagaaattat
     8881 tacagaggta ttaaaagaca aagaatttta cgaagaatcc ggtggaggtt taactttatc
     8941 aggaggtgaa atatttgctc agtttgaatt tgctaaagcc atcttaaaat cagctaaaga
     9001 acatcacata cacactgcca ttgaaactac tgcctttgtt gatcatgaaa aatttatcga
     9061 tttaattcaa tatgtggatt ttatctacac agacctaaaa cattataatt ctataaaaca
     9121 taaaaaagtg actggggttt ttaatcaaat gattattaaa aacattcatt atgctttttc
     9181 tcaaaataaa actatcgttt taagaatccc agttattcct aattttaaca atagtttaga
     9241 ggatgcagaa aaattcgcta ctctatttaa ctcattaaat atcgaccaag ttcaactact
     9301 cccttttcat caatttggtg aaaacaaata tcgtttatta aatcggaaat atgaaatgga
     9361 tggagtcaac gcacttcatc ctgaagatct tattgattat caaaaggtat ttctgaacca
     9421 ccatattaat tgttatttct agttcatttc cttgaaatgc tctagctatt tgcagataac
     9481 aagcatctat ataaggttat caaagaagac ttccccatga ctctaaatga atatatctta
     9541 caatatcgcc tgaaacaagc tatagataag atggctgaat ctcccaactc ccctttaagc
     9601 gctatctctg accaagttgg attttcagac tataaatatt ttgccaaagt atttaaaaag
     9661 tatctccata tttccccaaa gaaattgaaa tcactcggaa gaatagtaaa ataggctatt
     9721 cttctttttg tagagaattt tactctaata tagtgaattg aaataagatg tgaacatctc
     9781 tatcaggaaa gtcaaattaa tttatagaaa tattttagca gtcaaagtgt actgttatag
     9841 attcaataca ctatagaata gaattgtagg ttttaaaaac gcttacattg ttttaaaata
     9901 aacttaaata acacaacgga gatatcccat catgaaaaag aaatggatgt attatgctgc
     9961 ttgttcttct aatgaatctg ccgatgacag ttcatctgat aaaggagacg gtggttcgct
    10021 agtcgtttat tgaccaaact cagaggactt aattggagca actattcctg cctttgaaga
    10081 aaaatatggt atcaaagtag aactgattca agctggtact ggagaacttt tcaaaaaact
    10141 agagtcagaa aaagaagttc ctgtagctga tgttatcttt ggtggttctt atacacaata
    10201 tgctacccac ggagaactct ttgaaaacta tacttcaaaa gaaaatgata atgttatcaa
    10261 agaatatcaa aacacaactg gcttctctac tccttataca ctagatggta gtgttttaat
    10321 cgtccaccct gatttaacta aaggcatgaa catcgaagga tatagcgacc ttctcaaacc
    10381 tgaactaaaa ggaaaaatcg caactgctga cccagcaaac tcttctagcg cctttgctca
    10441 attaacaaat atgctacaag ctcaaggtgg ttacaaagat gataaggctt ggtcttatgt
    10501 aaaagatctt ttcacactta ttgatggtat agtaaaatga aataagaaca ggacaaatta
    10561 atcaggacag tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt
    10621 ttcaatatac tataaaatcg gtttaagttc atctggtgtc tataaagcag tcgctgatgg
    10681 agaaatgact gttggtctct cttatgaaga tccagcagtt aaactcttaa atgacggagc
    10741 taacattaag gtagtctatc caaaagaagg aaccgtcttc ctacctgcta gtgctgctat
    10801 cgttaaaaaa tctaaaaata tggaaaatgc caagaaattt atcgatttta ttatctctca
    10861 agaagtacaa gatacacttg gtacaaccac tactaaccgt cctgttcgta aaaatgctaa
    10921 aacaagcgaa aacatgaaac caattgacaa aatcaaaaca ctcactgaag attatgatta
    10981 tgtcatcaag aataaatcag atatcgttaa gaaatacaac gaagtcttta cagatatcca
    11041 atctaaacag taaaagaggt tcactatgag tgagatcgaa attattaacg ccaaaaaaat
    11101 ctaccacgat gtctctgtta ttgagaattt gaacattaca attccaaaag gaagtctctt
    11161 tacccttctt ggagcttcag gatgtgggaa aacgaccctt cttcgtatga ttgcaggttt
    11221 caacagtatc aaagatggag aattttactt cgatgataca aaaatcaata atatggaacc
    11281 cagcaaacgc aatatcggga tggttttcca aaactacgct attttcccac atttgactgt
    11341 ccgagacaac gttgcttttg gtcttatgca aaagaaggtt ccaaaagaag aattgattca
    11401 acagaccaac aagtatcttg aactcatgca aattgctcaa tatgcggatc gaaagcccga
    11461 taaactcagt ggtggacaac aacaacgtgt caccttggca tgcgccttag cggttaatct
    11521 aagtgttctc ctcatggacg agccacttag taatctggag gccaaacttc gcttggatat
    11581 gcgtcaagcc atccgagaaa tccaacacga agtgggaatt acaactgttt atgtaaccca
    11641 cgaccaagaa gaagccatgg ctatttcaga ccaaattgct gttatgaaag atggggtgat
    11701 ccaacaaatc ggccgaccaa aagaactcta tcataaacca gctaatgagt ttgtggcaac
    11761 ctttatcgga cgcacaaata ttatccctgc caatcttgaa aaacggagcg acggcgctta
    11821 tatcgtcttt tcagatggct atgcccttcg aatgctagct cttgatcagg ttgaggagca
    11881 agctattcat gtaagcattc gtcccgaaga gtttatcaaa gatgaatctg gagatattga
    11941 aggaactatt agcgatagcg tctatcttgg actaaatacg gagtatttca ttgagacagg
    12001 ttttgcctca aaaattcaag ttagtgaaga atcaactttt gaagaagatc tacaaaaagg
    12061 caatcgtatt cgtctacgaa tcaatacgca aaaattaaac atcttttctg cagatggttc
    12121 ccaaaacctg ataaaaggag tcaaccatgg aacgtaaaaa actaaatatt tggacagcct
    12181 cctctttctt catctttctt acctatcttg tctttctcgt ttatcctatc gttaccgtgc
    12241 tcaagtaagc acttatacat gaaggacaat tctcactagc taattttgtc actttcttta
    12301 gtaaagtcta ctactctgag acactagtca acagtttcaa ggtttccatt accgctactg
    12361 tcacttcctt agttgtagga accctattag cttatctctt ctctatgtat gacttcaagg
    12421 gggagaaatt tctacaaata ttgattatca ttgcttccat gtcagctcct ttcgtaggag
    12481 cctactcctg ggttctcttg ctaggacgaa atggggtcat cactaaattt ttgacaaatg
    12541 cccttcatct tccagctatc gatatttatg gattcaaagg aattgtactt gtctttacac
    12601 tgcaactatt cccactggta tttctatatg ttgctggaac aatgaacagt attgacaatt
    12661 ctctacttga agcagctgaa agcatggggt ccttcggatt taagcgtatc gtaacggttg
    12721 ttttacctct cctagttcca accttactag cagttccttg cttgtattta tgagagcatt
    12781 ctcagacttt ggaacgccta tgttgattgg cgaaggatat cggactttcc ctgtcctgat
    12841 ttatacccaa tttattagcg aggttggagg aaattctgct tttgcaatta tggcgattat
    12901 cattgccttg gcgattttcc ttatccaaaa acacattgca aaccgctaca gtttcagcat
    12961 gaatctgctc catccaattg agcctaaaaa aactacaaaa ggaaaaatag ctgccattta
    13021 tgcaacagtc tacggaatta tctttatctc tgttttacct caaatctact taatttatac
    13081 ctctttccta aaaacatcag gtatggtatc tgttaaaggt tattctccaa acagttacaa
    13141 ggtagctttc catcgtatgg gatctgctat tttcaatacc attcgtatcc ctttgattgc
    13201 cttagttcta gttgttctat ttgcgacatt tatctcctac ctagccgtta gaaaacggaa
    13261 tttgtttaca aacttaattg acagcctcag tatggtacct tatattgtac caggaaccgt
    13321 tctagggatt gccttcattt cttccttcaa tactggtcta tttggaagtg gatttcttat
    13381 gattacaggg actgctttca tcttgattat gtctctatct gtcagaagat taccttatac
    13441 tattcgctca tctgttgcta gcttacaaca aatagcacca agtattgaag aagctgctga
    13501 aagcttagga agtagtcgtc tcaatacctt tgctaagatt acaactccaa tgatgctatc
    13561 tggtatcatt tctggagcca tcttatcttg ggtcacaatg atttcaaaac tctctacttc
    13621 tatcctcctc tacaatgtca aaacaagaac aatgactgta gctatttata cagaggttct
    13681 cagaggaaat tacggtgtag ccgcagcctt gtcaactatc ctgactgttc taacagtagg
    13741 ttccttgctc ttgtttatga aaatctctaa aagcaatagc attacacttt agttttccac
    13801 atcaaaaaca gccgaaagga gtaccctcgg ctgttttttc ttatcttgat attcttatca
    13861 aatccctagc tcatggcaag caagtctaga ctgattaaat agagccttct tccatcttct
    13921 cacgtcctag ctctcggtaa ctacggtcac cgacaacttc aaccctaaac tgaccgtcct
    13981 catattcaag aatcgtcacg ctaccattat ctagaccatg cggatgcatg ccattaatca
    14041 gataaacaat ggttccaata gtcattccat ggctgacaac aagggcgtta cctccacctt
    14101 gatcttccat ttcttttgca atcatttcaa agccttcctt gattcggcca ctgagttttt
    14161 cccagccttc agcccaacca gctgtatcga cctctaccaa gccctcagcc agttcagcat
    14221 aagacaattg gtgaacgtgg tccacattaa agatacgagg aataatgccc atgaaaagat
    14281 cgccatcata ggctccatca aaactaccga aacaccattc tctgatacgc ttgtccatgc
    14341 gataagggat tttcccctgc aagccaagtt cttcaaggat aattcccatg gtctgaatgg
    14401 tacgaccaga atcactcgaa taagcgcgct caaactgtag atcagattct cgcaaaccga
    14461 ttcctaactc ttgaatccct cgttcacctt cagcagttaa gggagtatcg ctccaacctt
    14521 gcgcgcgacc aatcgtgtta aacatggtct tgccatgacg taccaaatac aatcgtactt
    14581 ttaccatttt ccgtcctccg tttgcttcta ttatatcatg aatgataaaa taaaagccac
    14641 ccatacaggc gacttttgaa ggagattatt atgaaaaagt ttaggagttc attaaataaa
    14701 gatattagat gaaaatcaaa ttcaaactaa ttcagtgtta tctgtttcaa ataatattag
    14761 gaggtcttta tttaatgatt atagtataca cgtctaatct taaatagaac ttaaaatttc
    14821 tcctattttc ttaattttta aaactatgaa ttggtgctgg gatttgtcca ccgcgagaga
    14881 tgaagtcgac agacgaagcc ccattaacct tcataacagg tgcagttcct aatagaccac
    14941 caaactcaat catatcgcct tctcttcctt tgggaatgat acgaacagct gttgttttca
    15001 tgttgataac accgattgct gcttcatccg caatcatagc cgcaatggtt tcagcaggcg
    15061 tatcttctgg gatggcaatc atatccaatc caacagaaca gatagccgtc atagcttcta
    15121 gtttttctaa attaagagag ccattttgca ctgcagcaat cattccttca tcctcagaaa
    15181 cagggataaa ggcaccagat aaaccaccga cttggttgca ggccatcact ccaccctttt
    15241 taacttggtc gttcaagagg gccaaggcag ccgtcgttcc atgcgtgcca actgtttcta
    15301 gccccatttc ctcaaggaca cgtgccacag agtctccaac cgcaggggtt ggtgccaaac
    15361 tcaagtccac aataccaaac tccacaccca gtctctcact ggccatttga ccaaccaatt
    15421 gaccgatacg agtgatttta aaggcagttt tcttaactgt ttcggctact acatcaaagc
    15481 tctgtccacg aactttttcc aaagcacgtt tcacaacacc aggaccagaa actccgacat
    15541 tgatgataac atctgcttcc ccaacaccat gaaaggcacc cgccataaat ggattgtcct
    15601 caacagcatt agcgaataca accaacttgg ccactcccat atctgaaaga tttgctgttt
    15661 ccttgataat tcgtcccata tctgccacag ccgtcatatt aataccagac ttggttgagc
    15721 cgatattgac tgacgagcag accttatccg tctcagccaa agcgcgagga atggaattga
    15781 tgagaatctc atctcccttt tgataacctt tttgtactaa ggcagaaaaa ccaccaataa
    15841 agtccacacc aatctctttc gcagccttat caagcgcttt tgccagaacc acgtagtccg
    15901 tcgcatctgt cgctgcccca atcagagaaa taggtgtcac cgatacacgc ttattaacga
    15961 taggaattcc caactcagcc gcaatttcat caccaacagc tactaaatta gccgcctttg
    16021 tcgtaatttt ttgatagatt ttctccgcag cacgattgat atttggatcg atacagtcca
    16081 aaagagaaat ccccatggta atggttctaa tatcgaagtt ttgctcctca atcatggcga
    16141 tggtttcagt aacttgtcta atatccatga tgacctccta gatattatac atagcttcga
    16201 aaatcgctgc actctgaata ttgattttta cattcaaagt ttgcccaaaa gcttcaaatt
    16261 cattacgaag ataggtaaaa tcttgctttt catcactaga tacaacagcc atcatcgtaa
    16321 aatattcatc caagacagtt tgagagatat cgtcaatatt caatcctaat tctgcaattt
    16381 taccagaaac acctgcaaca attccagatt tatctttacc aacaacagtt ataatggctt
    16441 tcataagtaa actccaattc ttcttaaaat aagaaacctt aacattaaac aggattcttt
    16501 tcaaatagta tagcataatt ctaacgaaaa tactcaaaaa cgcctgctta cgaagttgtt
    16561 cttaagaaaa aaacaatttc gtaaacaagc gtctactatc ccaacttatg atgagtgttc
    16621 ccgctaggac cgaaatccta gcggtagacc agagctagac taagagcaca agactccatc
    16681 atcataacac tcaacaaaat tgatgatttt atactaattc gatgatcgcc attggcgctg
    16741 catcaccacg acgtggttca gttttaagga tacgagtgta tccaccgtta cgttcagcat
    16801 aacgaggtgc gatttctgag aacaattttt gaagtgctgt agtagaagtg tacttatcag
    16861 ttgcttcatc atagttttca gatgcgattt cattacgtac gaaagcagct gcttgacgac
    16921 gtgcatgcaa atcaccacgt ttacctagag taatcatttt ttcaacagtt ttacggattt
    16981 ctttagcacg agcttcagtt gtcacgattg attcgttgat caaaaggtca gttgtcaaat
    17041 cgcgaagcat tgctttacgt tgtgagctag tgcgtcctag tttacggtaa gccatgtatt
    17101 cctcctttat ttatctttta atccaagacc caaatcaatg agtttgagtt tcacttcttc
    17161 caaactcttg cgtccaagat ttcgtacttt catcatctct gcttcagatt tttctgtcaa
    17221 atcatgcaca gtattgatac cggcacgttt taaacagttg tatgaacgca cagacaaatc
    17281 cagttcctca atcgtacgat ctaaaatacg gtcgtcagat tcagtatcag cttctttcat
    17341 cacttcagtt gacttagcaa tctcagtaag atttgtaaac aaatcaagat gttctgtcaa
    17401 aatacgtgct gaaagcccta aagcatcttc tggaataatt gttccatttg tcaagatttc
    17461 aagggttaat ttgtcgaaac catcattgct acctacacga gcaggttcca cttgatagtt
    17521 gacttttgta actggtgtat aaatagaatc tacagcaagt gttccaactg gtgcattatc
    17581 ctttttattt tcatcagcag gtacatatcc acgaccactg ttaacagtca tagtcgcttt
    17641 tagagaagaa ccttcaccaa ttgtaaagag ataatgatct ggatttacaa tttcaatatc
    17701 gctatctgtc aaaatgtcac cagctgttac ttcagcagga ccttcaacat ccagttcgat
    17761 gattttttcg tcttcaacgt acgatttcac tgcaattcct ttaatgttca gaatgatttg
    17821 catcacgtct tcacgaacac ctggaactgt gtcaaactca tgtaacacac catcaatgtt
    17881 gatagatgtc acagctgctc ctggtagaga agctagaagt acacgacgaa gagagttacc
    17941 aagagttgta ccgtagccac gttcaagtgg ttcgattaca aacttgccat aatctttatt
    18001 ttcatcaatt tttgttatat ttggtttttc aaactcgatc atttagttac tccctcttaa
    18061 acgaaaagca gtgtaatgcg atgattatac acggcgacgt tttggaggac gagcaccatt
    18121 gtgtggcact ggagtcacat cacgaattgc tgttacttca agaccagcgg cagcaagcgc
    18181 acgaatagct gactcacgac cagaacctgg accttttaca gtaacttcaa ctgatttaag
    18241 accgtgttct tgtgcagatt tagcagcagc ttcagaagcc atttgagcag cgaatggtgt
    18301 agatttacga gaacctttga aaccaagagc accagctgat gaccaagcaa ttgcattacc
    18361 atgcacatca gtaatcataa caatagtgtt attaaatgta gcgtgaatat gagcaatacc
    18421 agattcgata ttctttttca cacgacgttt acgtgttggt ttagccaaga cttttacctc
    18481 ctatattatt ttttcttacc agcaatcgca acagctttac ctttacgagt gcgagcgttg
    18541 tttttagtgt tttgtccacg gacaggaagt ccacgacggt gacggatacc acggtatgaa
    18601 ccgatttcca tcaaacgttt gatgttcaag tttacttcac gacgaaggtc accttcaact
    18661 ttgattgcat ccacttcacg acggatagca tcttcttgat ctgatgtaag atcacgtaca
    18721 cgaacatctt ctgagattcc agcagcagcc aaaattttct tagatgttgc aagtccgata
    18781 ccataaacat aagtcaatga gattactacg cgtttgtcat ttggaatatc aactccagca
    18841 atacgagcca tgttttctcc tttctatctt atccttgacg ttgtttgtgt tttggatttg
    18901 ctgggcaaat taccataaca cgaccattac gacgaataac tttacagtat tcgcaaattg
    18961 gtttgaccga tggtcttact ttcatttctt atccctccaa gtttttcgat tatttaaagc
    19021 ggtaagtgat acgtccacgt gtcaagtcat atggactcat ttcgacagta acacgatctc
    19081 ccgctaaaat acgaatatag tttttacgaa ttttaccaga aactgttgct aaaatctgat
    19141 gtccattttc aagttcaacc gtaaacattg cattcggcat tgtatcaact actttgcctt
    19201 caacttcaat cacatcgtct tttgccacgc aaaagcacct ccataaattt cgattcgatg
    19261 cctctagaca cagagacaac aattataagt cagactatct cagtataaca tttgtagcgg
    19321 attttggcaa gtgtgaaaaa cgctttattt caaatttgtc aatacttttt caatatctga
    19381 gaagacatca ttgatatctt gattaccttc gatgtcatga accaaacctt tggcacggta
    19441 gtgagcaatg attggttctc cttgagcaat attaacatcc aaacgacgtt ttactgtctc
    19501 aggcttatca tcttcacgtt ggtagtaatc ttcttcttta tagtcaactg gtgggttaaa
    19561 gaccttgtgg aaagtttctc cagttacgcg gtggatgata cggccactca aacgttccaa
    19621 aaggctgtca gggttcactt caatattgat aacaccttct agttcaatgc caagttcagt
    19681 caatgttttg tccaaggcat gagcttgttc aattgtacgt gggtaaccat ccaataagaa
    19741 tcctgtttct ttaatatcat cttgtgaaag acgttctttt acgattccat ttgtaacttc
    19801 gtcaggaacc aattcaccct tgtcaatata tgacttagca agaacaccca tttcagtttg
    19861 atttgccatt gcagcgcgga acatatcacc tgttgagata tgtgcaacat ggaattgttc
    19921 tacgattttt gctgcttgag ttcccttacc tgcaccaggt aagcccataa tcaaaagatt
    19981 catgatttga tctccttatt ttatttttaa atagaagcaa aaagtctttt cacccctatt
    20041 taaaaacaaa atagaagagg ggagatccaa ctcttacaaa tgtcagagtt taaacctcca
    20101 ctccctcagc atttactgat tcagtaaata cttttattct gttctgtcca tgaaaccaac
    20161 atacttacgt ttcaataggt aaccttccaa ttgcttgatt ccttcgatac ctgtagagat
    20221 aatgatcaag agacttgttc caccaaaggc aacaacatca gaaagaccaa atacatcttt
    20281 agctgcaatc ggtaaaatgg aaatcacacc aaggaagagg gaaccaacag ttgcaagacg
    20341 acgaagaagt ttagacatat attcttctgt acctttacca ggacgaactc catggatata
    20401 ggcaccactc ttttgtaggc tctctgctgc tttttcagga ttaatctgta caaacgtata
    20461 gaagaatgta aagagaataa tcaacaaagc atacatggca ataccagttg gagaagtagt
    20521 tgccagcatc tcttgtgcta cccttaccca agcccaatca tgacctgtgg cactcaaaaa
    20581 ctgaagaata gccgcaggcg ctgcagtaat cgaactggca aagataacag ggataactcc
    20641 agcagggttt acctttaacg gaaggtaaga gctagatgga gcaccttgtg caaccttagt
    20701 atattggatt ggaattttgt attctgcttg ttgaacataa gttgtaaagt aaataatcaa
    20761 caatacagta ataatcaaaa tgattacgaa aatgatagat gaagtgatac ggctacttgg
    20821 gacgttcaca aagtagtcca catagatgcc ctgaatcatc tctggaattg aggaaacaat
    20881 cccggcaaag ataatcatgg aaacaccgtt tccgtatccc ttatctgtaa tttgctcacc
    20941 caaccaagtg acaatcatac taccagctgt taagatgata ccaatcgtca gaaaaacttg
    21001 tggagttaaa gcagttttaa tcaattgagc tccagccaag gtattaaaac cagctgtaat
    21061 cccgatagat tgcacaaaag cgagaactag agcaatataa cgagtagctt gattcaattt
    21121 tcttcgacct acttcccctt gtttacccca ctctacaaac ttgggtaaaa tatccatttg
    21181 caagagttgg acaacaatag aagcggtgat atagggacta actcctaggg caaaaatcga
    21241 aaagtttttt agggcattcc ccgacaccaa gctcaacatg tttaagaagg ataatccact
    21301 taaagcattc aagctattgg cattcacacc aggaactgta atgctagttc cgatacgaaa
    21361 gaccaaaacg ataaaaattg taaataaaat ttttgatcga acctgcttga ctttaagagc
    21421 ttctcttaat aatttaaaaa acataggtca cctctcttag atgacttcta ctgaaccacc
    21481 tttagcagtg atagcttctt cagctgattt agagaattta gctgctttca cagtcaattt
    21541 cttagtcaac tcaccgttac caagaatttt aatacctgac ttttcagctt taacaattcc
    21601 tgcttcgata agaacaactg gagttacttc agcaccatct tcaaagacgt tcaattggtc
    21661 aaggttcaca attgcgtatt ctttagcgtt gatgttagtg aatccacgtt ttggaagacg
    21721 acggaacaat ggagtttgtc caccttcaaa accaaggcga actccgccac cgctacgagc
    21781 tttttgacct ttttgaccac gaccagatgt tttaccgtta cctgatgaag taccacgacc
    21841 aacgcggtta cgtactttac gagaaccttc tgcaggtttc aattcatgaa gtttcatttt
    21901 tattttctcc tcttttgtaa aatgctagcg ccgataaggg agaaaaggtt gtctccccca
    21961 tcaactcgcc tatacgatgt catcatagat gactatatct agttttaggg gatggtacag
    22021 tgcacatccc ctaaaacttc attagtttac ttcttcaact gttactaagt gagatactgc
    22081 tgtaatcata ccacggatag cagcgttatc ttctttaata acagagctgt tcaatttgcc
    22141 aagtccaagt gctacaacag ttttacgttg tgatggaatg cgtccgattg gagacttagt
    22201 caaagtaatt ttaatttgag ccattttatc ccctttctta tgccaaatca gaaactgaaa
    22261 taccacgaag ggcagcaatt tcttcagcgc gtttcaattg tttcaaacct tcaacagttg
    22321 cacgaacaat gttgattgga gtgttagaac caagtgattt agatgtaata tctgccacac
    22381 ctgccaattc cacaacggca cgaactgcac caccagcggc aactccagaa ccttctacag
    22441 caggtttcaa caatacttta gctccaccga attctgaaag aacttcgtgt gggattgttg
    22501 ttccaaccat aggaacttcg atcaagtttt tcttagcatc atctactgct ttacggattg
    22561 cttctggaac ttcttgagct ttaccagtac caaatcctac gcgaccattg tggtcaccaa
    22621 caacaacaag agctgcgaaa cgaagacgac gtccaccttt aacaactttt gtaacacggt
    22681 tgacagcaac tacgcgttct tctaattcaa ctgcattgtc tttaaatgcc attttctagt
    22741 gtcctcctat tagaatttca atccgttttc acgagctgca tcagccaaag ctttcacacg
    22801 tccgtgatat agatatccac cgcggtcgaa caccacttct gaaatacctt tagcgtttgc
    22861 acgttctgca acgagtttac cgacagcaac ggcttgttca gttttagttc cttttgaaac
    22921 ttctttatca agagttgaag cacttgcgag cgttacaccc gctacgtcat caatcacttg
    22981 agcgtagatg cctgtattag aacggaatac gttcaaacgt gggcgatcag cagttccaga
    23041 gagttttccg cgaacgcgac ggtggcgttt ttggcggagt ttgtttttat ctggttttga
    23101 aatcacagtt ttcacctctt tagttttaaa tcgtgtgcta tgcacaaagt tggaaaatag
    23161 gttggtggtt gatgatcaac cactcaacat tatttacctg ttttaccttc tttacggcga
    23221 acgaattcac caacgtaacg gataccttta cctttatatg gttctggtga acgaaggcta
    23281 cgtacgtaag cagctgtttg accaactact tcttttgaaa ttccgctaac aacgattgtt
    23341 gttgggtttg gaagttcaaa agtaattcct tctggagctt caacttcgtc tggatgagat
    23401 ttaccaacag ccaaaacaag tttagatcct tgaagctgtg cacggtaacc aaccccacgc
    23461 atttcaagtt ctttcttgaa tccttctgat acaccaacaa ccatgttgtt caaaagggca
    23521 cgagtagttc cgtggatagt tttcatttct tttgaatcgt ttggacggtg aagagttatt
    23581 tcagtacctt ccacacggat ttcaatatct tttgagaact cacgagtaag ttctccttta
    23641 ggtcctttta cagttacaac gttgtcattg ttagcgagtt caacaccagc aggcaacacg
    23701 ataactttat taccaatacg tgacatgttt attttctcct gttaaattgt caggccagaa
    23761 cggccagttt tcacggggtt cagatactta tttagttcaa gagctgaact gaacacgctc
    23821 taagaactgt gcaaaataga taagttggct tgtttgtaaa caaacttctc caacttccta
    23881 attttgcttt gttctttacg agctttgtat cttgatttta ccaaacgtaa gcgataacct
    23941 caccaccaac attcttttgg cgtgcttctt tatcagtaag caaaccttca gaagttgaaa
    24001 ggatggcaat tccaagtccg ttaagaactt ttggaaggtc ttcacgtttt ttgtagacac
    24061 gaagtcctgg tttagaaaca cgtttcaagt tagtgataac tttctcacca tttggtccgt
    24121 atttaagaaa tacacggatg acgccttgtt tgtcatcttc aatgatttca acgtttttta
    24181 caaaaccttc gcgtttaagg atttcagcaa tccctttttt gatgtttgat gcaggtactt
    24241 caagtacttc gtgtttagct tggttagcat tacgaatacg agttaggaag tctgcgattg
    24301 ggtcagtcat aaccattttg tttttctcct cttactagta gtttgcaagt tgcacttgct
    24361 agttaataca tgatacaaag agcgtaacag cacgagcaaa aatagacaat ttaatgcaga
    24421 agcaatgctc caaagcaaat tagtcttttt tgccaaagct gtagctcgtg ttcaaattgg
    24481 caagcccaat tgaacccggg ctaaactctg tgtgaaaaag ataaactttc ctagaaactt
    24541 tagtttcttc gtcaagtttc ctatttttac ttggagtttt gacgctcttg atatcttaaa
    24601 ttaccaagat gcttttgtta caccaggaat ttgaccttta tgcgcaagtt cgcgaaaagc
    24661 gatacgactc agaccaaatt tgcggtaaac tgaatgtggg cgccccgtaa ccctacaacg
    24721 attatgtaaa cgagtcggtg aggcgttgcg aggtaattta gataaacctt cgtagtcccc
    24781 tgccgccttt aatgcagcac gtttttcagc ataacggtca acaatttttt ggcgtttagc
    24841 ctctctagct accattgatt ttttagccat tagatttacc tcctatatta ttttgcaaaa
    24901 ggcattccaa ggcctgtaag caatgcacgt gactcttcgt cagtgttagc agttgttacg
    24961 ataacgatgt caagaccacg agttttgtca acgtcatcga agttgatttc tgggaagatt
    25021 aattgttctt tcacaccaag tgtgtagttc ccgcgtccat caaatgattt tgttgggaca
    25081 ccgtggaagt cacgtacacg tggaagtgaa actgatacca atttatccaa gaattcgtac
    25141 atacgttcac cacgaagggt aacttttgca ccgatcgcaa caccttcacg aagacggaag
    25201 ccggcgattg attttttagc tttagtgata agtggttttt gacctgagat aagtgccaat
    25261 tcttcagcag ctttttcaag gcttttagcg tttgatacag cttcaccaac acccatgttc
    25321 aaaacaatct tatctacttt aggcacagcc atcactgatg agtagttgaa ttgttctgtc
    25381 aaagcaggaa ctacttcatt aagatatttt tcttttaaac gatttgccat tatacttctc
    25441 ctttccttcg tgattaatca agcacttcgc ctgatttttt gttgtagcga acttttttac
    25501 cgtctacaaa tttgtaacca acacgaccag ctacaccatt tttgtccaaa acttgaacat
    25561 ttgatacgtg gatagctgct tctttctcga tgataccacc ttgaggaagc tcgttagttg
    25621 gacgttggtg tttcttaaca atgttaacac cttcaacgat aactttgttt acttttggaa
    25681 gggcagtaag gacaacagct tctgttccct tatctttacc agcgattacg cgaactttgt
    25741 cgcctttttt tacaaacatt aggtttctcc ttgatttttc ttacgcccat aagggcaccc
    25801 tagcttgaag ctaggggact agtttgttcc taaaaattaa agtacttctg gagcaagtga
    25861 cacgatcttc atgaaaccac cttcacgcaa ttcacgtgca actgggccaa agatacgtgt
    25921 tccgcgagga gttttgtctt cacggatgat aactgctgcg ttttcgtcaa atttgatgta
    25981 tgaaccatca gcacgacgag cacctgattt agtacgaacg ataactgctt taacaacgtc
    26041 acctttttta accgcaccac caggagtagc ttgttttaca gatgccacga taacatcacc
    26101 gatgtttgca aatttacgtc ctgaaccacc aagaactttg atagtcaaga tttcgcgagc
    26161 accgctgttg tctgcgactt tcaaacgagt ttctgtttga atcatttcag ttttctcctt
    26221 tcaggtttga ttagatgatg accgcttctt caacaacttc tacaagacgg aaacgttttg
    26281 tagctgaaag cgggcgagtt tccatgatac gtacgatatc gccttctttg gcaacattgt
    26341 tttcatcatg agctttgtat tttttagagt agttaatacg tttaccatag actgggtggt
    26401 tacgttttgt ttcaactaca actgtgattg tcttgtccat tttgtcagat acaacacgtc
    26461 caacaagaac tttacgatta ttgcgttcca ttgaaatttc tccttcccta gtctattatt
    26521 tcgcttcaga ttgaactgtt ttgatacgag cgatttgttt tttaacttct ttcaagcgag
    26581 ctgtttgttc caattgacca gtagcagctt ggaaacgaag ttcaaacaat tcttttttca
    26641 attcgttttc gcgcttcgcg agttcttctt gagaaagacc acgaagttct ttaacaaatt
    26701 cttttacttc attaagtttc atgccttctc cttattctgc ttcacgtttt acgaatttac
    26761 atttaactgg caatttgtgg ctagcaagtc gaagcgcttc acgtgcaatc tcttcagata
    26821 caccagcgat ttcgaacatc actttaccac gtttaactgg tgctacccaa ccttcaggtg
    26881 cccctttacc agatcccata cgcacaccga tagctttagc agtgtatgat ttgtgtggga
    26941 agattttaat ccaaacttta ccaccacgtt tcatgtaacg agtcatggcg atacgagcag
    27001 cttcgatttg gcggttagtg atccagtggc tagttgtagc ttgaagaccg tattcaccga
    27061 atgctacttc ttttccacct tttgcttcac cgcgcatttt tccacggaac tcacgacggt
    27121 gtttaacacg tttaggtact aacattggtt atttacctcc tttagtgttt ttacgagctg
    27181 gaagaacttc accacggtag atccatactt taacaccaag tttaccgtat gtagtatctg
    27241 cttcttccca agcgtaatcg atatctgcac gaagtgtgtg aagcggaaca gttccttcag
    27301 agtatccttc agcacgggcg atatctgcac cgttcaaacg acctgatact tgagttttga
    27361 ttcctttagc tccagcacgc attgcacgtt ggattgcttg tttttgtgca cgacggaaag
    27421 caacacgttg ctccaattga cgagcaattc cttcacctac aaggtgagca tccaaatcag
    27481 gttgtttgat ttcgatgatg ttgatgtgta cttgttttcc agtcaatttg ttaagttttg
    27541 cacggagtgc atcaacgtta gcaccacctt taccgataac catacctggt ttagcagtgt
    27601 gaagtgaaac gttaactttg tttactgcgc gttcgatttc aatagttgaa actgctgcgt
    27661 cagcaagttc tttttgaacg aatttacgga ttgcaagatc ttcatgaagg taatccgcgt
    27721 attctttttc agcataccat ttggcatccc aatcacggat gatgccgaca cgcataccaa
    27781 ttggatgtac tttttgaccc acgattttac ctccttattt ttctgcaaca gctacagtga
    27841 tgtgagctgt acgtttgttg attggtgaag ctgaaccttt cgcacgtgga cggaaacgtt
    27901 tcatagttgg tccttcgttt gcgaatgctt cagatactac caagttagct ttatccaaac
    27961 caaagttgtt ttcagcgtta gctacagctg agttcaaaac tttcaagatg atttcagcag
    28021 ctttgtttgg agtgaatgtc aagattgcga ttgcatcggc tacgctttta ccacggatgt
    28081 tatcaagaac aagacgtgat ttacgaggtg aaacacgtac tgtacgagcc attgctttag
    28141 ctgaagtaat ttctgccatt tatgttctcc ttattttcta cgtgttttct tgtcgtctgc
    28201 agcgtgacct ttgtaagtac gagttggtgc aaattcacca agtttgtggc ctaccatgtc
    28261 ttcttggatg taaacaggta cgtgtttacg tccgtcataa actgcaatag tgtaaccaat
    28321 gaaacttggg aagatcgttg aacgacgtga ccaagtttta ataacttttt tcttttcgtc
    28381 gttagcttga gcttcaactt ttttcatcaa atgctcatcg acgaaaggtc cttttttaag
    28441 actgcgtccc atttttatat tttctccttt aaatgttgta ccacagcggc ttgcactcct
    28501 atggagcgct accgagctgg cggatttact agttgcttaa gcgactagtt taatattatt
    28561 tctcgttgcg acgacgaacg ataagtttgt cagatttcgc tttcttgtta cgagttttaa
    28621 gaccaagagc aggtttgccc catggagtag atggtgcttt acgaccaact ggtgctttac
    28681 cttcaccacc accgtgtggg tgatcgttag ggttcattac agaaccacga actgttgggc
    28741 ggataccttt ccaacggcta cgtcctgctt taccaaggtt tacaagtcca tgttgttcgt
    28801 ttccgacaac accaactgta gcacggcaag ttccaagaat catacgaact tcacctgatt
    28861 gaagacgaac aagaacatat ttaccttcag aacccaatac ttgagcagat gcaccagcag
    28921 cacgtaccaa ttcaccacca cgacctggtt tcaactcgat gttgtgaatc aaagtaccaa
    28981 ctgggatgtt agcaagtgga agagcgtttc cgactttgat atctgcttct ggacctgaaa
    29041 cgatacgttg acctacttca agaccttttg gagcgatgat gtatgctttc acaccgtcag
    29101 tgtagtgtac aagagcgatg tttgcagaac ggtttggatc gtactcgatt gttttaacaa
    29161 ctgcttcaac gttgtcttta ttacgtttga agtcaaccaa acggtagaaa cgtttgtgtc
    29221 caccaccttg gtgacgaact gtgatacgac cgttgttgtt acgaccagcc ttgctcttca
    29281 atgcaacaag caatgatttt tcaggagtgc ttgttgtgat ttcagcgaaa tccaaagaag
    29341 tcatattacg gcgaccgttt gttgttggtt tataaacacg aattcccacg atatttcctc
    29401 cttagattat tcagcttcag cagcaaacaa ctcgattgct ttagaatcag ctgtaagtgt
    29461 gatgatagct tttttagttt tgttagtaaa accagtgtaa cgtccaacac gtttagcttt
    29521 tggttttacg ttgattgtgt taacattggc aactttaaca ccttcgaaag cagcttcaac
    29581 agcttgcttg atcaaaagtt tgtgtgcacg agtgtcaact tcaaatacat atttccctgc
    29641 ttcaagttga gccattgagc tttcagtgat gacaggtttt ttgataacat catacaaatt
    29701 cattatgcaa gaacctcctc gattttagag atagctgctt gtgtgacaag aagtttgtcg
    29761 ctatttgcga tgtcaagaac acttgcagtt gtagcagttg caactttcac gtttggaagg
    29821 ttacgagctg aaagagctgc gaattcattt ccttcttcaa ggataacaag aactttagaa
    29881 tcgatgctca atgctgcaag aacttttgca aattcagcag tttttggagc tgtaaatgaa
    29941 agagcgtcta cagctacgaa tttgttttca gcaacttttt cagagtaaac taatttaaga
    30001 gctaggcgac gaactttttg tggaagtttg tagccgtatg aacgtggagt tggtccgaag
    30061 acaacaccac caccacgcca ttgtggtgag cggatagaac cttgacgagc acgtccagtt
    30121 cctttttgac gccatggttt gcgtccacca cctgatactg cagagcggtt tttaacagcg
    30181 tgtgttcctt gacgaaggct tgcgcgttgg ctgatgatta catcaaacac aactgattca
    30241 tttggttcga taccaaatac tgcatcgtta agaacaactt ggccagcttc tttaccagtt
    30301 tggtcaaata atgttacgtt tgccattgtg actgatttcc cctttcttta ttatttacca
    30361 gctttaactg ctgatttgat agtgataaga gatttcttag cacctggtac gttacctttg
    30421 ataaggataa cgttcttttc tggaacaact tgtacaactt caaggttttg aattgttacg
    30481 cggtcgccac ccatacgtcc tgcaaggttt ttacctttga atacgcggtt aggtgcaaca
    30541 ggccccatag aacctggacg acggtggtaa cgagaaccgt gagccattgg tccacgtgat
    30601 tgtccgtggc gtttgataac accttggaaa cctttacctt tagaagtacc agttacatca
    30661 acaacatctc cagctgcgaa tgtttcaact gtgatttcag cgccaacttc caagccttca
    30721 acgtttttga attcacgaat gaagcgctta ggagccgtgt tagctttcgc tacatgtcct
    30781 ttagcaggtt tgttgctcaa tacttcgcgt ttgtcatcga aaccaacttg gatagcgttg
    30841 tatccgtctg tttcaacagt tttaacttga agaacaacgt ttggagttgc ttcaataact
    30901 gttacaggga tcaattcgcc agcttcagtg aagatttgag tcattcccac ttttttccct
    30961 aagattcctt ttgtcatgag aaaatagttc cttttctata ttttttattc aaaaagtttt
    31021 taacgagcgt tttttatgct caagtctaag atacaaaggg cgtcaaactc aaagtgaaaa
    31081 taggaaacta acgcagtgtc tagcggacaa taggaagttt atctttttca caccgagttt
    31141 agcccgtgtt caattagatt gaaacaccag cctctgctct tttatatttt agattaaagt
    31201 ttgatttcta cgtttacacc acttggaaga tccaatttca tcaaggcatc aactgttttt
    31261 tgagttgggt taacgatatc gatcaaacgt ttgtgtgtac gcatttcaaa ttgttcgcga
    31321 gagtctttgt atttgtgagt cgcacgaatg attgtgtaga ggctacgttc agttggaagt
    31381 gggattggac ccgcaacttg tgcacctgta cgagtagctg attctacgat ttttgcagcc
    31441 gctgtgtcaa gcgtacggtg ttcgtaagct ttcaaacgga tacggatttt tttgtttgcc
    31501 atctttttct ccttttcgtc tatttaagat aataggctag ctccacaaga aaaccgacgc
    31561 ggtgttgcgt ggcaatgcaa ccgagcgtgt cgcaacctct tgcatcaaaa ctaaggctgt
    31621 aatttacagc accataatag aataacacaa atcccctgcg attgcaaggg atttgttagg
    31681 ttttttcgtt tttttgggat gaaactgttt tcctactttt tctttctaaa attagggatt
    31741 ttcttctata tttcttctat acataagtta agtcctcttg acatcaaatt tatcttctga
    31801 ttggtccact aagatatccg ccttagactc agtttcttta tagtatcgca gatactgctc
    31861 ccgtctcatc tgatggctag ccaatataaa ggatgcatag cgatttctca cagtcgtatc
    31921 tctagcaagg cgtcgcttta attcggtctc ctcatccgtg tagaaacaga tggttttttc
    31981 aaagagttcc ttgggtagaa aaccaacaga catcccttcg acaatcaaaa ttggtttggc
    32041 tccagacaag acctcactag ccttccaagg ttcttcaatt gtcaagacat ccatacccgc
    32101 ctgcaaggca aggatatctc tctgcaaact ctccagttca tgcgccactg gcagactggc
    32161 tgtcaccttt tgattcggcg cgtccttggg tactaccaaa tagcgtccgg aggtgatata
    32221 gggatctgtt tctagcaaat tta
//
LOCUS       DAVIME010000023        31749 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVIME010000023 DAVIME010000000
VERSION     DAVIME010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.023"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..370
                     /locus_tag="VV588_001135"
     CDS             <1..370
                     /locus_tag="VV588_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="flavoprotein"
                     /protein_id="HEU7083489.1"
                     /translation="EVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTATVLNF
                     NKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDSTCSMLQ
                     PQSLVKELIKLENIVLEEGH"
     gene            591..1697
                     /locus_tag="VV588_001136"
     CDS             591..1697
                     /locus_tag="VV588_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU7083490.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGSA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            1673..3064
                     /locus_tag="VV588_001137"
     CDS             1673..3064
                     /locus_tag="VV588_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083491.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKIRPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            3061..4239
                     /locus_tag="VV588_001138"
     CDS             3061..4239
                     /locus_tag="VV588_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU7083492.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            4664..4897
                     /locus_tag="VV588_001139"
     CDS             4664..4897
                     /locus_tag="VV588_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU7083493.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            5180..7129
                     /gene="mutL"
                     /locus_tag="VV588_001140"
     CDS             5180..7129
                     /gene="mutL"
                     /locus_tag="VV588_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU7083494.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(7454..7921)
                     /locus_tag="VV588_001141"
     CDS             complement(7454..7921)
                     /locus_tag="VV588_001141"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU7083495.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(7922..9127)
                     /locus_tag="VV588_001142"
     CDS             complement(7922..9127)
                     /locus_tag="VV588_001142"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU7083496.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(9147..9782)
                     /gene="ribE"
                     /locus_tag="VV588_001143"
     CDS             complement(9147..9782)
                     /gene="ribE"
                     /locus_tag="VV588_001143"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU7083497.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(9767..10867)
                     /gene="ribD"
                     /locus_tag="VV588_001144"
     CDS             complement(9767..10867)
                     /gene="ribD"
                     /locus_tag="VV588_001144"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU7083498.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(11001..11115)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            11272..11865
                     /gene="ruvA"
                     /locus_tag="VV588_001145"
     CDS             11272..11865
                     /gene="ruvA"
                     /locus_tag="VV588_001145"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU7083499.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            11875..12438
                     /locus_tag="VV588_001146"
     CDS             11875..12438
                     /locus_tag="VV588_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU7083500.1"
                     /translation="MTKRCSWVKMTNPLYITYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            12435..13112
                     /locus_tag="VV588_001147"
     CDS             12435..13112
                     /locus_tag="VV588_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7083501.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALIHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(13249..14279)
                     /locus_tag="VV588_001148"
                     /pseudo
     CDS             complement(13249..14279)
                     /locus_tag="VV588_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
     gene            complement(14534..15217)
                     /locus_tag="VV588_001149"
     CDS             complement(14534..15217)
                     /locus_tag="VV588_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU7083502.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(15229..16173)
                     /locus_tag="VV588_001150"
     CDS             complement(15229..16173)
                     /locus_tag="VV588_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU7083503.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            16305..19136
                     /gene="uvrA"
                     /locus_tag="VV588_001151"
     CDS             16305..19136
                     /gene="uvrA"
                     /locus_tag="VV588_001151"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU7083504.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILASVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            19129..20190
                     /locus_tag="VV588_001152"
     CDS             19129..20190
                     /locus_tag="VV588_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU7083505.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            20322..20720
                     /gene="spx"
                     /locus_tag="VV588_001153"
     CDS             20322..20720
                     /gene="spx"
                     /locus_tag="VV588_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU7083506.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            20786..21355
                     /locus_tag="VV588_001154"
     CDS             20786..21355
                     /locus_tag="VV588_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU7083507.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGTATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            21442..21708
                     /locus_tag="VV588_001155"
     CDS             21442..21708
                     /locus_tag="VV588_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU7083508.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            21712..22131
                     /gene="ruvX"
                     /locus_tag="VV588_001156"
     CDS             21712..22131
                     /gene="ruvX"
                     /locus_tag="VV588_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU7083509.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            22147..22452
                     /locus_tag="VV588_001157"
     CDS             22147..22452
                     /locus_tag="VV588_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU7083510.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            22711..23961
                     /locus_tag="VV588_001158"
     CDS             22711..23961
                     /locus_tag="VV588_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU7083511.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKDGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMREGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            23958..24500
                     /locus_tag="VV588_001159"
     CDS             23958..24500
                     /locus_tag="VV588_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU7083512.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            24646..26178
                     /gene="cls"
                     /locus_tag="VV588_001160"
     CDS             24646..26178
                     /gene="cls"
                     /locus_tag="VV588_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU7083513.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIMEIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            26256..26399
                     /locus_tag="VV588_001161"
     CDS             26256..26399
                     /locus_tag="VV588_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083514.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            26436..27974
                     /locus_tag="VV588_001162"
     CDS             26436..27974
                     /locus_tag="VV588_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU7083515.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     YFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILY
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            28094..30301
                     /gene="nrdD"
                     /locus_tag="VV588_001163"
     CDS             28094..30301
                     /gene="nrdD"
                     /locus_tag="VV588_001163"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU7083516.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTD"
     gene            30313..30453
                     /locus_tag="VV588_001164"
     CDS             30313..30453
                     /locus_tag="VV588_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083517.1"
                     /translation="MGKYQLDDKGCAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            30497..31003
                     /locus_tag="VV588_001165"
     CDS             30497..31003
                     /locus_tag="VV588_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083518.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            30996..31586
                     /gene="nrdG"
                     /locus_tag="VV588_001166"
     CDS             30996..31586
                     /gene="nrdG"
                     /locus_tag="VV588_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU7083519.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            31594..>31749
                     /locus_tag="VV588_001167"
     CDS             31594..>31749
                     /locus_tag="VV588_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-triphosphate reductase"
                     /protein_id="HEU7083520.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNPNY"
BASE COUNT         9584 a         5734 c         6719 g         9712 t
ORIGIN      
        1 agaggtagtt ccgcacgttt ttctgccata tgaatctgac ttacttctta ttttaccagc
       61 tacggcaaat gtgattggca aaattgctaa tggtattgct gatgatttag ttacagcaac
      121 tgttttaaac tttaataaaa aaataatttt ttgtcccaat atgaactcta ctatgtggga
      181 caatcacata gttcaaagaa atgtatcaat tctaaaggag ttgggacata tatttttatt
      241 tgagtctaaa aaaacatatg aggtaggatt gcgtaaagca atagattcaa catgttcaat
      301 gttacaacca cagtcgttag taaaagaact tatcaaatta gaaaatattg tccttgaaga
      361 gggacattaa aaactactga gaatattaag gaggggaaaa aatggaaaat tcatcaatcg
      421 atgtagatat gctgttggaa gaattgacac aagaagcaat ggtcgttgtt gctgttgata
      481 aggactgtta atttaaactt atggcaatat atgaaaggtt actggatgtt ttaaattatg
      541 caggcagtag ccttttatta tatacaaatg gataaagtaa ggataataca atgattaata
      601 aaaaaataca acaagttgtt ttggaatcat tacagaattt tttgaatggg aacttcattt
      661 cgccttgtgt agtctatgat tttggcttgc tggaaactgt acttgatgaa tttaaaaatc
      721 aaattcctgt aacattcaat taccaacttt tttatgccgt taaagcaaat tcaaatgaga
      781 agatacttga attcttagta gataaaattg atggagttga tgtggcgtca ttatctgaat
      841 tagatgtggc taaaaaattt ttcccaccaa ctcaaatttc tgttaatggt tccgcatttt
      901 cttatgaaac tttatataat ctgattaaaa aacaatataa agttgatatt aactttttgg
      961 aacatcttca acaattttcc ccaaaagaat ctgttggaat aagagtaacg gagccagatg
     1021 aacttaataa tcgtatgagt cgatttggaa taaatatttg cagtgataat tggactagta
     1081 atttacaaaa tcctttaatt acacgactgc attttcattt tggagaaaaa gatgataaat
     1141 ttattgttaa gttagataaa atattattta agttacaaga aattaataaa cttagagagg
     1201 ttagagaaat aaatcttgga ggcggtttta tgaaattatt tatggaaaat cgtttgaaag
     1261 aattttttct atcacttatg gaaatctata aaaagtacga tattgatagt actgtgacta
     1321 caataataga accaggtagt gcaattactt cattttctgc ctatatgatt actagcccag
     1381 ttaatgttag tgaggtgaat gagcagcagg ttatcacgtt agacacatca atatacacca
     1441 atacattatg gtttgttccg catattatta caacgttaaa ttcaagtagt aaagagcgtt
     1501 atagtactat tctctatggt aatacctgtt atgaacatga caagtataaa atgaaagttt
     1561 cgcttccaag gttaactcaa aatagcagta tagtgttttt tcctgtagga gcttatataa
     1621 aaagcaatca ttcaaattta catcgtaatg attttatgcg ggaggtatat ttgtggacaa
     1681 aaaacttgac atattagata aagttaagga atatttagga aataaaacta ctcaaattct
     1741 ggataatcaa tataaagaat ttttgaaact taatgatata aggcgagcgt ttggtatttc
     1801 agaaaaagta ttaaacaatt cttttaattt tacgagtaaa gaatttaatg atttaattaa
     1861 taacgaaaat tatttattcg aatatgcatg tagaattaga gaggaatgga gaaaaaaatg
     1921 ctttaatcat tcttatcgtt ttctatgctc acctataatt acagatgatt ttcttaacac
     1981 gaagacattg agaagtagcc aaattgaata taaatatgag cgatatttat cgaaaagttc
     2041 gataggcgat agagcggttg atggctttgt ttccttcaat actttaacag ctaatggtat
     2101 gtctgctatt aaactatgtc ttgagatatt aaactctatt ttcttcaaga agaagattga
     2161 tttattatat tcaaccggat attatgaaac aagattttta ttaaataatc ttgctaaatc
     2221 aggtattagt tgctatgagg taagtaattg tgaattggat aaagataaat tttataatgt
     2281 attcatgatg gaacccaatc gagccgattt aacattacaa aaaactgatt tcaagatagt
     2341 agaatatttt gttaagtata aaaataattc aataaaagtc gttattttag atatttcata
     2401 tcaaggttct aattttaaat tagtagaatt tttagagaaa tttaaatttg cgaatgtaat
     2461 tatttttgtg gtacgatctt tgataaaatt agatcaaatg ggattagaat tgacaaatgg
     2521 gggaataata gaagtgttta ttcctaatca tttgagaaag ttgaaaaatt ttattgaaga
     2581 ggaattcaat aaatttagaa attctcacgg agctaatcta agcctctatg aatactgttt
     2641 gcttgataat tctttaactt taaaaaatga ttggaactat tctgatttag ttatgaaatt
     2701 tacgagtaat ttttatgctg atataaaaga cttgttcatg gaaaattctg atattgaaat
     2761 catccatgaa gagggagtac cttttgtatt tttagattta ataggtgaag gtaaaaaaga
     2821 atatgaaatg ttttttcaat ggttaaactt cttttacaaa cagcttggaa tcacattgta
     2881 tgctagaaat agttttgggt ttcggaatct aacagtagag tattttggaa ttattgggac
     2941 agaaagatat atatttaaga ttcgtccagg tgtttataaa gggttaagtt attatttgat
     3001 gaaattttta ttaaaatctt tttcaaatga atatttaaaa actactgatg aggttaatag
     3061 atgaaaaatt tgataaagtt gctaataatt agattgattg ttaacttagc agacagtgta
     3121 ttttatatag tagcattgtg gcacgttagc aataattatt cttcgagcat gttcttagga
     3181 atatttattg cagtaaatta tctaccggat ttgttactaa tcttttttgg accagttatt
     3241 gacagagtaa atccgcaaaa aattcttata atatcaattt tggttcaatt agcagtggct
     3301 gtaatatttt tattattatt aaaccaaata tcattttggg tgataatgag tctagtgttt
     3361 atttcagtaa tggctagctc cataagttac gtgatagaag atgtgttgat tcctcaagtg
     3421 gtagaatatg ataagattgt atttgcaaat tctcttttta gtatttcgta taaagtatta
     3481 gattctattt ttaattcatt cgcatcattt ttacaggtgg cagtaggatt tattttattg
     3541 gttaagatag atataggcat atttttactt gctctattta tattgttgtt gttaaaattt
     3601 agaactagca atgcgaatat agaaaacttc tctttcaaat attacaagag agaagtgttg
     3661 caaggtacaa agtttatttt aaataataaa ttattattta aaaccagtat ttctttaacg
     3721 cttataaact ttttttattc atttcagaca gtagttgtac cgattttttc tattcgatat
     3781 tttgatggtc cgatttttta tggtattttt ttaactattg ctggtttggg tggtatattg
     3841 ggaaatatgc tagcgccaat cgtaataaaa tatttaaaat cgaatcaaat tgttggtgta
     3901 tttctttttt tgaacggctc aagttggtta gtagcaattg ttataaaaga ctatacttta
     3961 tcacttattt tatttttcgt ttgttttatg tctaaaggag tcttcaatat tatttttaat
     4021 tcgttgtacc aacaaatacc tccacatcaa cttcttggta gggtaaatac taccattgat
     4081 tctattattt cttttggaat gccaattggt agtttagttg caggaacgct tattgatttg
     4141 aatattgaat tagtgttaat tgctattagc ataccttatt ttttgttttc ttatattttt
     4201 tatacggata atggattgaa agaatttagt atatattaga aatgtttatg ttcattcaaa
     4261 agcataatga ctataactga aaaagaaaag tgatatcttt aaggttgttc ttcttggtgg
     4321 tgagattcgt gagacaaccc aagcttttgt cggaaagatt accaatgctt tgatggatag
     4381 gatgtacttt agcaagatgt ttttagtggt aacggtatcg tggatggacg tgtaataacc
     4441 tcttctttcg aggagtattt tactaaaaaa ctagccttgg agcgttcccc agaaacggac
     4501 ttactcattg actcttcaaa gatttgggga gaagattttg cttcatctgt tacttgaaaa
     4561 aagtcacagc agtcatcaca gacgatagta ctgaacaaaa ctatgaagag ttagaaattt
     4621 atacgcaggt gattgtataa aggatctgga aatagataag aagttgatta gtattgacct
     4681 aggtggtaca aatattaaga ttactgttct ttcaaatgac ggtgagattg aaactttgtg
     4741 gagtattaca acagatacaa gtgagaaagg ttctcaaatt atatcggaca tcatcagttc
     4801 tattaaaaat aaattgaccg aacggaatat tcctgatagc gaccttcttg gaatcggtat
     4861 gggaagttgc tcatcatact ttccttgtaa atcatagggg ctataaactc tccgtctact
     4921 tgtcctgcaa caattgaagt ctgctcaaaa cgccgtccgc taatcttttc atagactttc
     4981 tcccttttag gagcctagct ttctagtttg ttctttgatt tttattgagt ataccactat
     5041 tttactccct ctggcaaggg actttgtcta tgtggaggga ttgggctcct atgtggtgga
     5101 gcttttctgt tctttctgaa atatggtata atagcactaa tcaatttcta ggaaaataga
     5161 tacagaaagg ggctgaaaga tgtctcatat tattgaattg ccagagatgc tggcaaacca
     5221 aatcgcggct ggagaggtca ttgaacgtcc tgccagtgtg gtcaaagagt tggtagaaaa
     5281 tgccattgac gcgggctcta gtcagattat cattgagatt gaggaagctg gtctcaagaa
     5341 ggttcaaatc acggataacg gtcatggaat tgcccacgat gaggtggagt tggccctgcg
     5401 tcgccatgcg accagtaaga taaaaaatca agcagatctc tttcggattc ggacgcttgg
     5461 ttttcgtggt gaagccttgc cttctattgc gtctgttagt gtcttgactc tgttaacggc
     5521 ggtggatggt gctagtcatg gaaccaagtt agtcgcgcgt gggggtgaag ttgaggaagt
     5581 catcccagcg actagtcctg tgggaaccaa ggtttgtgtg gaggatctct ttttcaacac
     5641 gcctgcccgt ctcaagtata tgaagagcca gcaagcggag ttgtctcata tcattgatat
     5701 tgtcaaccgt ctgggcttgg cccatcctga gatttctttt agcttgatta gtgatggcaa
     5761 ggaaatgacg cggacagcag ggactggtca attgcgccaa gcaatcgcag ggatttacgg
     5821 tttggtcagt gccaagaaga tgattgaaat tgagaactct gacctagatt tcgaaatttc
     5881 aggttttgtg tccttgcctg agttgactcg ggctaaccgc aattatatca gcctcttcat
     5941 caatggccgt tatattaaga acttcctgct caatcgtgct attttggatg gttttggaag
     6001 caagcttatg gttggacgtt ttccactggc tgtcattcac atccatatcg acccttatct
     6061 agcggatgtc aatgtgcatc caactaagca agaggtgcgg atttccaagg aaaaagaact
     6121 gatgactctg gtttcagaag ctattgcaaa tagtctcaag gaacaaacct tgattccaga
     6181 tgccttggaa aatcttgcca aatcgaccgt gcgcaatcgt gagaaggtgg agcaaactat
     6241 tctcccactc aaagaaaata cgctctacta tgagaaaact gagccgtcaa gacctagtca
     6301 aactgaagta gctgattatc aggtagaatt gactgatgaa gggcaggatt tgaccctgtt
     6361 tgccaaggaa accttggacc gattgaccaa gccagcaaaa ctgcattttg cagagagaaa
     6421 gcctgctaac tacgaccagc tagaccatcc agagttagat cttgctagca tcgataaggc
     6481 ttatgacaaa ctggagcgag aagaagcatc cagcttccca gagttggagt ttttcggaca
     6541 aatgcacggg acttatctct ttgcccaagg gcgagatgga ctttacatca tagatcagca
     6601 cgctgctcag gaacgggtca agtacgagga gtaccgtgaa agcattggca atgttgacca
     6661 gagccagcag caactcctag tgccctatat ctttgaattt cctgcggatg atgccctgcg
     6721 tctcaaggaa agaatgcctc tcttagagga agtgggcgtc tttctagcag agtacggaga
     6781 aaatcaattt attctacgtg aacatcctat ttggatggca gaagaagaga ttgaatcagg
     6841 catctatgag atgtgcgaca tgctcctttt gaccaaggaa gtttctatca agaaataccg
     6901 agcagagctg gctatcatga tgtcttgcaa gcgatctatc aaggccaatc atcgtattga
     6961 tgatcattca gctagacaac tcctctatca gctttctcaa tgtgacaatc cctataactg
     7021 tcctcacgga cgtcctgttt tggtgcattt taccaagtcg gatatggaaa agatgttccg
     7081 acgtattcag gaaaatcaca ccagtctccg tgagttgggg aaatattaaa agtataaaaa
     7141 agtctgggaa aaattttcaa aatcagaaaa acgcataaaa tcaggtgttc aaaaaccttg
     7201 attttatgcg ttttatcata gaaatattta cttcattttt tcctaattct tttcgaaact
     7261 ctttttaaac cacgtcagtt ttatcagtaa tctcaaaaca gtgttttgag ctaattttgc
     7321 cagttttgtc tgtaacatcg aagttgtgtt ttaccactct gcgactggtt tcctagtttg
     7381 ctctatgatt ttcacagagt attaaattgc gattttgcca agtttcttta ttcgtctaaa
     7441 agtagagtct gttctatgcg tctaatgtac gaattaggtt gaccatttca atagctcctt
     7501 gtgcacactc agaaccctta tttcctgctt tagtaccagc tcgttctatg gcttgttcaa
     7561 ttgtatctgt cgttaacaca ccaaacataa caggaatttc gctatttaaa ctgatttggg
     7621 cgattccctt agatacctcg ctacatacat aatcataatg acttgtattc cctctaatga
     7681 cagctcccaa gcagataatt gcatcatatt ttttactttt tgccattttt gatgcaatca
     7741 gtggtatttc aaaagctcct ggaacccagg ctacctcgat atctttctcg tttacattct
     7801 ctcttttgag attatctagt gctccagata ataattttga agttataaat tcattaaatc
     7861 tcgctacaac aatacctatt ttaatattgt ttgctactaa attaccttca taagtgttca
     7921 tttatttttc ctccatattt aaaatgtgac ccattcgatt tttctttgtt tctaaataaa
     7981 aactatcgta aggattggct tctatttcga ttgatattct actggaaatg gtaattccat
     8041 atttttctaa ctgttcaacc ttgtcaggat tatttgtcag taaatgaagt gactgaagtc
     8101 ccagatcttt aagcatttgt gctccaatat gatattctct taaatcacct tcaaagccta
     8161 atgcaagatt ggcatcaagc gtatccatgc cttgatcttg taaatgatag gcttttaatt
     8221 tattgataag tccaattcct cgtccctcct gtcgcaagta aagtaagaca cccgaaccat
     8281 tctcaacaat cattttcata gctttatcga attgctgtcc acaatcgcaa cgtaaagagc
     8341 ctaaaacatc tcctgttaaa cattcggagt ggacccgaca taatacattg gcttcatcct
     8401 ctatgtttcc cataataaga gcaagatgat gttccccatt tagtttatct atatagctaa
     8461 ttgctttgaa attaccgtat ctagtaggca tattgacagt tgaaactcgt tctaccagct
     8521 gatcatatac ttttctatat tcttgtaatt ctttgatggt aattagtgga atgttgtgtt
     8581 tcttcgagaa ctgaattaaa tcatctgttc tcatcatttt gccatcatga ttcattattt
     8641 cacaacatag gccacactct tttagtccag ctaattttaa taaatcaaca gttgcttctg
     8701 tgtgtccatt tctttctaga acaccacctt tttttgcaat taaaggaaac atgtgtcctg
     8761 gcctgcgaaa atcagagggt gttatatctt cagctacaca catacgtgcg gtcagtcctc
     8821 tttcctcggc agaaatacct gtggtcgttt ctttataatc aattgaaact gtaaaagcag
     8881 tcttatgatt atctgtattg ttttcaacca taggtgaaag cattaattga ttagctaaac
     8941 tttcgctcat aggcatacaa attaatcctt tggcataagt agccataaaa ttaacatttt
     9001 ctgttgtagc tgcttgtgca gaacaaatta agtctccttc attttctcta tccttgtcgt
     9061 ctataacaag aacaagtcgt cccttctgca atgcttctaa tgcttcttgt atttttcgat
     9121 attccattga ctgattatcc tttctgctaa aatccatttt gatataatag ttccttagat
     9181 atttctgatt ttggagagtt atccatcagt ttttgcacat atttacctaa gatatcattt
     9241 tcaagattta ctgtactccc gacttgttta ctcttaagaa tggtttgttc caaggtatga
     9301 gggataacag atactgaaaa gtttactttg gagactttag cgacagtcag actaatgccg
     9361 tcaattgtaa tagatccttt ttcaactatt aaatctaaaa tttctttttg tgtgttgatt
     9421 tgataccata cagcattatc atcttttttt attgacgaga tttttcctgt accatcaatg
     9481 tgtcctgtaa cgacgtgacc cccaagtcga ccgttgacag ataaggctct ttctagattc
     9541 acctcacttc catgttttaa tagagtaaga gctgttcgac tccatgtttc attcattaca
     9601 tcaactgtaa aggattgatg attgaaatga gtaactgtaa gacagatacc atttactgct
     9661 atactatcgc ctaaatggat atccgttaat atttttgagg ctttaattga tagtttacaa
     9721 ttacgagagt ctttctgtat tctttcaact tttccgattt cttcaattat tcctgtgaac
     9781 atggataaat cacttcactt tctatgagat agtcatttcc tatttgagaa aaagcataag
     9841 gtttcaatct aatagcgtca tttggcaaag aaatgccttc acctccgaca ggaaacttgg
     9901 cactgcctcc aaaaattttt ggtgcaatat atattttcag ctcatcaaca atttgttgtt
     9961 ccaaagcact ccaattcatt agactgcccc cttctagaac taggctatca atctgcatgt
    10021 ttcctagatg ttgcattaaa ctcgataagt ctatatgatt gccttttttc tttatggaaa
    10081 gtatttcaca gccatgattt tgatatagct tcattttatt tttgtcttca gaggaagtgg
    10141 caatgtaagt tttaatatca tttgctgttt ttacgatttt agaggtaaga ggagttcgta
    10201 aatgtgtatc gcatatgata cggataggat ttttcccttc ctccaatcta catgtcagca
    10261 aaggatcgtc ttgaataaca gtattgactc ccaccataat tgcactaaca tagtgtcgta
    10321 actgatgcac atgctttctt gcttcttctt cagtaatcca tttggattga tttgttttag
    10381 tggctatttt tccatccatt gacattgcat atttcataaa aacatagggt acatgctggg
    10441 taatatactt tctaaaactt tttattaagt taagacactc attttctaaa attccaacag
    10501 taacttgaag attattttcc tcaagtatct ttactccttt tccagataca ataggattac
    10561 agtctaggct tccaatgact actcttgtaa taccactatc gattatagca tctatacagg
    10621 gaggtgtttt cccgaagtga caacagggtt caagtgttac ataaagcgtc gctccgacag
    10681 gggattttct acagttttta agagcatttc tctcagcatg tgggccacca aaaaactcat
    10741 gataaccttg tccgataatg tgattatctt ttacaataac tgcgccgacc ataggattgg
    10801 gattgacgta accagcccct ttttgtgcca gttttattgc taatttcata tattttgaat
    10861 cgctcatctc actacctcca aaaaaatata ccttgaatag gggactactc aaggcataca
    10921 aaagaaaact tatgcgatta acaaaaatgc tctgaaatga caagtaatca tttcagagca
    10981 cgcaaaaagc acaaatatac ttttatcttc tttcatccag actatactgt cggctttgga
    11041 atttcaccaa atcatgcctt tcggctcgtg ggctatacca ccggtaggga attgcaccct
    11101 gccctgaaga tagttattca attacagatg attatagtac ttaattttga atatgtcaac
    11161 agataaatac cgattgtttt tgatatactg tatttgtgat aatcgattct cgctcctcgg
    11221 ataaagaaaa tatgatatac tagataaacg aaataagaga gaaggaacac tatgtacgca
    11281 tatttaaaag gaatcattac caaaattact gccaaataca ttgttcttga aaccaatggt
    11341 attggttata tcctgcatgt ggccaatcct tatgcctatt caggtcaggt taatcaggag
    11401 gctcagattt atgtgcatca ggttgtgcgt gaggacgccc atttgcttta tggatttcgc
    11461 tcagaggatg agaaaaagct ctttcttagt ctgatttcgg tctctgggat tggtcctgta
    11521 tcagctcttg ctattatcgc tgctgatgac aatgctggct tggttcaagc cattgaaacc
    11581 aagaacatca cctacttgac caagttccct aaaattggca agaaaacagc ccagcagatg
    11641 gtgctggact tggaaggcaa ggtagtagtt gcaggagatg accttcctgc caaggtcgca
    11701 gtgcaagcaa gtgctgaaaa ccaagaattg gaagaagcta tggaagccat gttggctctg
    11761 ggctacaagg caacagagct caagaaaatc aagaaattct ttgaaggaac gacagataca
    11821 gctgagaact atatcaagtc ggcccttaaa atgttggtca aataggagca gagaatgaca
    11881 aaacgttgtt cgtgggtcaa gatgaccaac ccgctctaca tcacctatca tgatgaggag
    11941 tggggccagc ccctccatga tgaccaagca ttgtttgagt tgttgtgtat ggaaacctat
    12001 caggcaggcc tgtcttggga aacggtactc aacaaacgcc aagctttccg agaagccttt
    12061 catagctatc aaattcactc agtcgcagag atgactgaca ctgaattgga agccatgctg
    12121 gagaatccag ctatcattcg aaatagagcc aagatttttg ctacacgcgc taacgcccaa
    12181 gcctttctac agttacaggc agagtacggc tcttttgatg cctatctttg gtcttttgtt
    12241 gaggggaaaa ctgtcgttaa cgatgttcct gattatcgcc aagccccagc taaaacaccc
    12301 ttatctgaga aattagccaa agatctcaaa aaacgaggct tcaagttcac aggcccagtc
    12361 gccgtattgt cttttctaca ggctgcaggg ctagttgatg accacgagaa tgattgtgag
    12421 tggaaaggtc ttaaatgatg tctaacaaaa ataagggaat tctgattttt gcgattctct
    12481 atacagtcct ctttgtgttt gatggcgtta aattgctggc ttctttaatg ccatctgcca
    12541 ttgcaaatta tcttgtttat gtagttttag ctttatatgg ctccttcttg ttcaaggata
    12601 gattgatcca acaatggaag gagattagaa agactaaaag aaaattcttc tttggagtct
    12661 taacaggatg gctctttctc attctgatga ctgttgtctt tgaatttgta tcagagatgt
    12721 tgaagcagtt tgtgggacta gatggacaag gtctaaatca gtctaatatt caaagtacct
    12781 ttcaagaaca accactactg atagctgttt ttgcttgtgt cattggacct ctggtagaag
    12841 aattattttt ccgtcaggtc ttattgcatt acttgcagga acggttgtca ggtttactaa
    12901 gcattattct ggtaggactt gtttttgctc tgattcatat gcacagtttg gctctatcag
    12961 agtggattgg tgcagttggt tacttaggtg gaggccttgc cttttctatt atttatgtga
    13021 aagaaaaaga gaatatctac tatcccctac ttgttcacat gttaagcaac agcctctcct
    13081 taatcatttt agctatcagt atagtaaaat gaaatgagaa caggacaaat cgatttctaa
    13141 caatgtttta gaagtagagg tgtactattc tagtttcaat atactgtaat atgtgatgaa
    13201 aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt atttgttata
    13261 gtcaaagaga atgacttgtt cctgtgcatc tacatgagca tggaccccaa agggtacaat
    13321 tgctcttgga gttgcgtggc cgacattcag attatagaca atcgggatat tgctgtcaat
    13381 gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag gttttccgac
    13441 caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca acatcttttt
    13501 gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt tcccttccca
    13561 gtctgacaag tcagggaaaa gtttgtattt ttggcagagt tccgtgctat ctgcgtatcg
    13621 agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt tcccctcgaa
    13681 ctgggcactt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac gaggtgttcc
    13741 cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag ggcggatttc
    13801 tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg ctagcatttc
    13861 tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct tgattcctaa
    13921 tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa ttttttgttt
    13981 gatacccttt tggagttggt cattttcaaa aagataaggt agcaagcgat aggcatcgtc
    14041 tccaccgatg gcacatagga tcatgtcgat ctatcatcag aaaaggcatg aatcaaatcc
    14101 tctgcacgag cttcaggatg gtccttgata aagtctaatc cttttaacga atggggcaaa
    14161 aagatgggat tgagtcccag atccttgaga cgttggatac ccaagtccac ttcgtgtttg
    14221 acaaaatcct ctccgataat gccactagat aaactaacaa taccaatagt agaaaccata
    14281 tctcatcctc ctagaaatag attgagccta ttttatcaca aaatataaga gaaagctatg
    14341 tgggatttca gaagaatact tttaatactc ttcgaaaatc tcttcaaacc acgtcagttt
    14401 tatttgcaac ctcaaagctg tgctttgagc aacctgcagc tagcttccta gtttgctctt
    14461 tgattttcat tgagtataac tcaaaaaagt aagtgaaaaa gcaaccgcac ctgcagttgc
    14521 ttttatcgtt ttcttattct tgatagcgtg ttggtcctgc acttgcacta cggatattca
    14581 agcgtttctt gagatagaag cgaagggcta ggagggctgc tccaataata gctagtggca
    14641 atggatccag tactgggtta aggctagctg gtaggaagct tgttgcaaag aagacaagca
    14701 accaaaggaa catagaagct aggataacta gtacagattt ccagaaaggt ggacgttgac
    14761 tgcgatccat atctggtcca tagtattggt aaacaaagta gtacatcaag tagaaggcaa
    14821 atccaccaac cagtccaact aatagaagag taatcaatcc atagccgaaa gcttgatctg
    14881 ccgcaaagaa ggttgtgagg gcgctgacaa gggcaaagag gctagtgatg aaaagagctg
    14941 agtccataat catcagtttt ggatcatcat tttcttttgg atgctctttt tcgtactgct
    15001 ctttgacagt gaagctatga gcccaatgag ttggtgcgcc gtatagggaa cgggcagttg
    15061 tacctttaga ttgctcctca aggatttggg gaatgacttc ctcaaaaata gtctggattt
    15121 cagcgtctgt tttcccatct ttgatgaatt gttgggtagc aatgtggaca aactcttggt
    15181 ttttcttagt taatttttgt agatcaattt gagacatagg aactcctctt agaaccattt
    15241 tttatggatg agatagagag tgagcgagac actcatagca aaggcgataa agacgattaa
    15301 ccagaaggca tttggctctc cgtttagggg gatttcatta tccttaaagt tcatcccgta
    15361 ggcagaaaag accatggttg ggatggacat gacgatggtc acaagggcca aggttttcat
    15421 gatgttgttc tggttgttag aaatgataga ggcaaaggtc tctgtcatag aatgcaagac
    15481 gtttccataa atatctgcca tctcgatggc ctgttgggtt tcaatcaggg tgtcttcaag
    15541 caggtcttcg tcttcaaggt atttcttgat attgctggtt gaactggtca atttcttaat
    15601 cacgcgctca tttgttttga gggaggcctt gaaatagacg atagtttttt ccaattccat
    15661 gagctcaatc aattcttcat tacgagttga ttgatgcagt tgactttcga tttgttcact
    15721 cttgcggtcg attgaacgaa gggctgttag gtaaagctct gcattgcgat aaagaatttg
    15781 aaagataaaa cgtgaacgca tgaaggtata gaaattacgc aatcgacggt tgataaagac
    15841 atcaaggaca ggtagtggtt ccaaacacgt agtgataatg gtttcctcag tgatgataat
    15901 accaagcggg atggttacgt agtaggtgcg gttatttctt tcctccgtga ccggcacgtc
    15961 tacgataatc agggtatact cgtcttcaat ggtaatacga gacatttctt ccgcatcgag
    16021 cggtgctcga aggtcggcaa tatcaatatc gaaggtgttg gcgatttcga gtgattcatt
    16081 ttgagtcgga ttgacgagat tgatccaagt acccggttca agcgtatcga tctctttaaa
    16141 ttcagttgtt gtagagagaa aaacttgttt catatccctt atcctttctc atttttcaga
    16201 ttttttcaca ctgtactatt atactacaaa atcggccttt tgggtaatag aatctcactt
    16261 tttttggtat aatggtaagc aataatggac tagaaagaac aaagatgcaa gataaaattg
    16321 tcattcatgg ggcgcgtgcc cataatttaa aaaatattga tgtggagatt ccgcgagaca
    16381 agttggttgt cgtgactggc ttgtcaggtt cagggaagtc cagtctggct tttgataccc
    16441 tctatgcgga gggacaacgt cgctatgtag agagtttgtc cgcctacgct cgtcagttct
    16501 tgggaaatat ggaaaaacca gatgtagatg ccattgatgg tctcagtcca gctatttcta
    16561 tcgaccagaa aacgactagc aaaaaccctc gctcgacggt gggaacaacg actgaaatca
    16621 atgactatct gcgtctcctc tacgcacgtg tggggacgcc ttactgtatc aacggacatg
    16681 gagctatcaa tgcttcttct gtggagcaaa tcgttgataa ggttttggag ttacctgaac
    16741 gccagcgctt gcagatcttg gcctctgtca tccgcaagaa aaaaggccaa cataagagtg
    16801 ttatcgagaa ggttcagaaa gacgggtatg ttcgtgtccg tgtggatggg gaagtctatg
    16861 atgtgaccga agtgccagag ttgtctaaga gcaagcaaca caatatcgat gtcgtggttg
    16921 accgtattgt tatcaaggag ggcattcgta gtcgtctctt tgattccatt gaggctgccc
    16981 ttcgtattgc agaaggttat gtcattatcg acaccatgga cgactctgag ttgttgttct
    17041 ctgagcatta tgcctgtcca gtttgtggtt ttactgtccc agagttagag cctcgtctct
    17101 tctctttcaa tgctcctttt ggctcttgta gtgagtgtga cggcttgggc atcaagctgg
    17161 aggtggatac tgatttggta gtgccagatg ccagcaaaac cttacgtgag ggagcgttag
    17221 caccttggaa tcctatctca tccaactact atccaaacat gttagagcag gccatgaaag
    17281 tatttggagt ggctatggat aagccttttg aggacctgtc agaagaagat aagaacttga
    17341 ttctctatgg gtcagatggt aaggaattcc atttccacta tgagaatgaa tttggtggcg
    17401 tgcgcgatat cgacattccg tttgagggag ttatcaataa tatcaaacgt cgttaccatg
    17461 aaaccaatag cgattacact cgcactcaga tgcgtctcta catgaatgag ctgacctgcg
    17521 gaacctgtca aggctatcgt ctcaatgacc aggccttgtc tgtccgtgtg ggcggccagc
    17581 aagggccaca tattggagaa atctcagacc tgtctatcgc tgaccacttg gacttggtga
    17641 gccagttaac tttgtctgaa aatgaagcca tcattgctcg tcccattctc aaggaaatca
    17701 aggatcgttt gaccttcctt aataatgtgg gtcttaacta tctaaccctg tcacgttcag
    17761 caggaaccct ttcaggtggg gaaagtcagc gcattcgttt ggcaacccag attggttcca
    17821 acctatcagg cgtcctctat atcctagacg agccgtcaat cggtcttcac cagagagaca
    17881 atgaccgcct gattgccagt ctgaaaaaga tgcgtgactt gggcaatact cttatcgtgg
    17941 tggaacacga cgaagatacc atgcgtgaag ctgattatct gattgacgtt ggtcctggtg
    18001 ccggtgtttt tggtggtgag attgttgcag caggtacacc taagcaagtg gctcgcaaca
    18061 gcaagtctat cacaggtcag tacttgtcag gcaaacgtgt catcccagta ccagaagagc
    18121 gccgtgtcgg aaatggtcgt tttattgaag tgataggagc gcgtgagaac aacttgcaaa
    18181 atgtcacggc tcgctttcca ctaggaaaat ttatcgcagt gacaggtgtg tcgggttcag
    18241 ggaaatcgac tctaatcaac agcattctca aaaaagccat tgcccagaag ctcaaccgta
    18301 attcagacaa acctggtaag tttaagacta ttacagggat tgagcatgtc gaccgtttga
    18361 ttgatattga ccagagccct atcggacgga cgccgaggtc taacccagct acctatacag
    18421 gagtttttga cgatatacgt gacctttttg ctcagacaaa tgaagccaag attcgaggct
    18481 acaagaaggg gcgcttcagt ttcaacgtca agggaggtcg ctgtgaagct tgctcaggtg
    18541 acgggattat caagattgag atgcacttct tgccagatgt ttatgtggct tgtgaagttt
    18601 gccacggaac ccgctataac agtgaaaccc tagaagttca ctacaaggaa aagaatattt
    18661 cgcaggtctt ggatatgacg gtcaacgatg cggtagaatt tttccaacac attccgaaaa
    18721 ttcaacgcaa actccagacc atcaaggatg tagggctagg ctatgtgacc ttgggacagc
    18781 cagctaccac cctttctggg ggagaagccc aacgtatgaa gttagctagc gaactccaca
    18841 aacgctcgac aggaaaatct ttctacattc tggatgagcc gacgacaggg cttcatacag
    18901 aggacattgc tcgcctgctc aaggttttag ctcgctttgt agacgatggc aatacagtcc
    18961 tcgtcatcga gcacaatctg gatgttatca agacggcaga ccatatcatt gacttgggac
    19021 ctgagggcgg tgtcggtggt ggaaccatca tcgtaacagg aactccagaa gaagtagctg
    19081 ccaatgaagc cagctataca ggacactatt tgaaaggaaa gttacatcat gaataaacgc
    19141 gtacaagcat ttctagctaa aatgcaagaa aaagaactag atggtatcat catcaacaat
    19201 cttaaaaacg tctattattt gactggtttt tggggctcaa acggaacagt ctttatcagc
    19261 cgtgaccgtc aggtcttagt gacagactct cgctatatca tcgcagctaa gcaagaaacc
    19321 agtggttttg agattgtggc tgatcgtgat gaattggctg tcattgcagg aattgttaag
    19381 gacatgggct tgactcgtat cggttttgaa gatgagattt cagtatctta ttaccaccgt
    19441 atgcaggcag cttttgcagg tttggacttg cttccacaaa ctcaatttgt ggaaggtctt
    19501 cgtatgatta aggatgaggc agagattgca gcgattcgca aggcttgttc tatctcagac
    19561 caagctttcc gcgatgcgct tgactttatc aaaccaggaa aaactgaaat tgaaattgcc
    19621 aacttccttg atttccgcat gcgtgagttg ggagcatcta gcttatcttt tgatacgatc
    19681 ctagctagcg gtatcaattc ttctaaaccc catgcccatc caatgcacaa accagtggag
    19741 ttgggagaag ccattaccat ggacttcggc tgtctctatg accactatgt cagtgatatg
    19801 acccggacta tctatctagg gcatgttagc gatgagcagg cagagattta caatacggtt
    19861 ctaaaagcta accaagcctt gattgaccaa gctaaggcag gcttaggttt ccgtgacttt
    19921 gacaaaatcc ctcgtgatat tatcattgag gcaggttatg gcgactactt tactcacggc
    19981 attggccacg gtattggtct ggatatccat gaggaaccct actttagcca gacttctaca
    20041 gaaactatta agacaggtat ggccttgacc gatgaaccag gtatctatat cgaaggcaaa
    20101 tatggcgttc gtatcgagga tgatatcctg attacagaga caggttgtga attattgacc
    20161 ctagctccaa aagagttgat agtcatttag ttgtttgtca agaaaaaagt acgaaaatga
    20221 cgaaaaaagt caaaaaaaat taaaaatagg tcgcaagtcg gatgtttttt atggtataat
    20281 agactaaact gatagtaaca tgtagcgaaa ggggtaggta catgattaaa atttatacag
    20341 tctcaagttg tactagctgt aaaaaagcaa aaacctggct caatgcccac cagttaagtt
    20401 ataaagaaca aaaccttggt aaagaaggaa ttacgagaga agaattactg gatattctaa
    20461 ccaaaacaga taacggaata gccagcatcg tttcgtctaa aaatcgctat gccaaagccc
    20521 ttggagtgga tattgaagat ttgagtgtca atgaagttct caatctgatt atggaaacac
    20581 cgagaatttt aaagagccca atccttgtag atgaaaaacg cctgcaagtt ggctacaagg
    20641 aagacgatat tcgtgccttc ctaccacgct ctgtccgtaa tgtagaaaat gcagaagcac
    20701 gtttacgtgc agctctataa acatcaaggc tgggagcact tcccagtctt attctatttt
    20761 aatttcaaaa agaaagaaga gagaaatgaa aaaaatagtt cttgttagtc tagctttcct
    20821 ttttgtcctg gttggttgcg gacagaaaaa agaaactgga acagctacaa aaacagaaaa
    20881 ggatacgctt cagtcggcat tgccagttat tgaaaatgcc gagaagaata cagttgtaac
    20941 caagactttg gtcttgccca agtcagatga tggtagccag caaactcaaa ccattacata
    21001 caaggacaag acttttttga gcttaacgat tcaacaaaaa cgtccagttt ctgatgagtt
    21061 gaagacttat atcgaccaac atggagtgga agaaactcaa aaagctcttc ttgaagcgga
    21121 ggagaaggat aagtctatca ttgaagctcg taaattggca ggtttcaaac ttgaaacaaa
    21181 actattgagc gcaacggaac ttcaaacaac gactagtttt gattttcaag ttctggatgt
    21241 caagaaggct tcccagttgg aacatctgaa gaatattggt ttggaaaatc ttttgaaaaa
    21301 tgaaccaagc aaatatattt cagatagatt ggcaaatggc gcgacagaac aatagaaaat
    21361 ccaaataaat agactgcctg aattgtagaa ggtaaggaat tatgctataa tggtactatt
    21421 ctaaggaaag agggtgttag aatgggattt actgaagaaa cagtacgttt taaattggac
    21481 gattccaata aaaaagaaat tagcgaaact ttgacagatg tttatgcttc gttgaacgat
    21541 aagggttaca acccaattaa ccaaatcgta ggttacgtat tgagtggaga ccctgcctac
    21601 gttcctcgtt ataataatgc acgaaatcaa atccgtaagt atgagcgtga tgaaatcgtt
    21661 gaggaattgg ttcgttacta cctcaaagga caaggagtcg atctataacc tatgagaatt
    21721 atgggattgg acgtcggttc aaaaacggta ggggtggcga ttagcgatcc gcttggtttt
    21781 acagctcaag ggcttgaaat catccagata aatgaagaac aaggccaatt tggttttgac
    21841 cgcgttaagg aattggttga tacttacaag gtagaacgat ttgtagtggg cttgcctaaa
    21901 aacatgaaca atacaagtgg accgcgcgta gaagctagtc aagcctacgg agcaaagcta
    21961 gaagagtttt ttggtttacc agtagactat caggatgaac gcttgacaac agtggctgct
    22021 gagcgcatgt tgattgaaca agcagatatc agtcgcaata agcgcaagaa agtcattgat
    22081 aagttagcag ctcagctgat tttacaaaat tatttagata gaaaatttta atataaagga
    22141 gaggctatgt cacacgatca taaccacgac cacgaagaac gtgaactaat cacactagta
    22201 gatgagcaag gaaatgaaac cttgtttgaa atccttttga caattgatgg aaaagaagaa
    22261 tttggtaaaa actatgttct tctagtacca gttaacgcag aagaagacga agacggacaa
    22321 gttgaaatcc aagcttactc attcattgaa aatgaagatg gaacagaagg cgaattgcaa
    22381 ccaatcccag aagactcaga agacgaatgg aacatgattg aagaagtctt caacagcttt
    22441 atggaggagt gatacagtct gggagactgt atcagcccaa ctcccagaaa tggggaagag
    22501 ttggaacgtc cagtgaacat ttttacccca actcttagaa cttgagaaga gttggaacat
    22561 ctagtggatg tttttagccc atattcacat tcatagtagc tagttattag ctaaccaggt
    22621 aagaggtcgg gacgaaaatc ctggccttgt ttttattagt aaccatactt taatgcgata
    22681 attgattgga cttttgtcaa ggagatgtgt atgtttgaag tagaagaatg gctccatagt
    22741 cggattggtt tgaattttcg atcaggtttg ggccgaatgc agcaagcggt ggatttgtta
    22801 ggaaatcctg agcagtctta ccctattatc cacgtaacag ggactaatgg gaaaggatct
    22861 accattgctt ttatgaggga attatttatg gggcatggca aaaaagttgc gacctttacc
    22921 tcccctcata tcgtctctat caatgaccga atctgcatta atgggcaacc tatagcagac
    22981 gcagacttta tccgtttgac tgatcaggtc aaagagatgg agaaaacgct tctgcaaact
    23041 cctgcccagt tgtccttttt tgaattgctg accttagttg cttttcttta ttttagggag
    23101 caggaggtgg atttggtttt attagaagtg ggaattggtg gcttacttga cacgaccaat
    23161 gtggtaactg gagagcttgc tgtcatcacc tccattgggc ttgaccatca agaaaccttg
    23221 ggtgatagtc tagaagcaat tgcagagcag aaagctggta ttttcaagga tggtaagaag
    23281 gcagtgattg cgaaattgcc tccagaagct aggcttgtct gtcagaaaaa agccgaatct
    23341 ttagctgtta acctttatca ggcaggtcaa gattttttaa tgctgaatgg tgatttttca
    23401 agctctttac taaatctttc acagctgaac ataggcttag aaggagtcta tcagcaggag
    23461 aatgcagcct tggcgttgca aacttttctt ctttttatga gagaaggaaa ggaagctgtt
    23521 gatgaacagg ctgtaagaaa ggccttggaa cagacccatt gggctggtcg cttggagcgt
    23581 attcgcccac agatttactt ggatggtgct cataacctcc ctgccttgac tcgcttggtt
    23641 gagtttatca aagaaaaaga gcaggaaggc tatcgacctc aaatcctctt tggatccttg
    23701 aaacggaagg attatcaagg gatgttgggt tatctgactg aaaatttacc tcaagtggaa
    23761 ctcaaaatga ccggctttga ctatcaaggg tctttggacg agacagatgt cacaggttac
    23821 catgtaattc cctcttaccg agaatttatc agcagtttcg aagaaagggc agacgctcaa
    23881 gacttgctgt tcgttacagg gtctctctat tttatctcag aagtacgggg ctacctgctg
    23941 gaccgtgagc agataaattg acccccttgt ttgaacttgt tatactaggg gaattgctgg
    24001 ttagagaaaa tttctctaaa ttggtagcag aaaggaaatt catcatgaaa ttaaaaagat
    24061 tcacactttc tcttgcttct ctagcaagtt ttagtctctt agtagcttgt tcacaaagag
    24121 ctcaacaggt tcaacagcct gttgctcagc aggtccaaca gcctgctcaa cagaatacca
    24181 atactgcaaa tgcaggaggt aaccaaaatc aagcggctcc agtacaaaac caacctgttg
    24241 ctcaaccgac cgatattgat gggacttata ctggtcagga tgacggagac cgtatcactt
    24301 tagtggtaac tggaacgact ggtacatgga ctgagctcga atctgacggg gatcagaaag
    24361 tcaaacaggt tacatttgat tcagcaaatc aacgcatgat tattggcgat gatgtcaaaa
    24421 tttacactgt aaacggtaat caaatcgtcg tagatgatat ggatagagac ccatcggacc
    24481 aaatcgtttt aactaaataa gactatgcaa gtagaaaggg ctggattttt cagccttttt
    24541 acttttacct agaaaataat cataaatact tgccttctac cgaatacctg cgttatacta
    24601 gtatcaatta cttgttttta gcattcaaac tatcaaggag gggatatgaa atataggaaa
    24661 tttcaattat tgatgtccaa gtatggcttt agtctttcga ttatgctact tgaactttgt
    24721 cttgtttttg gtctctttct ttatttagga cgcatggctc ccattttatg gattactgtc
    24781 ctcattctac tgagtatcat cacaatcatt tcgatagtca accgtaatac gactcctgag
    24841 aataaggtaa cctggttgtt agtagccttt gtgccagtat ttggtccctt gctctatctg
    24901 atgtttggtg aaaggcgatt gtccaaaaaa gaaatcaaac aactgaagaa gctaggctct
    24961 atgcatttcc aagaagcaaa tagccagcta ctaaaagaga aattaaaaga aagtgacaag
    25021 gcagcttatg gagtcatcaa gtccttattg agtatggata ccaatgctga catctatgat
    25081 caaactgcct ctacattttt tcctaacgga gaagctatgt ggaaaaagat ggtagaagat
    25141 cttaaaaagg ctgagaaatt tattttcttg gaatattaca ttatagaaga aggtttgatg
    25201 tggaatcgca tactagatat actagagcaa aaggtagctc agggtgtaga ggttaagatg
    25261 ctctatgatg atatcggctg tatggctact ttaacaggag attatgcaca tcgacttcgt
    25321 cagctgggca tcgaggccca taaattcaat aaagttattc ctcgtttgac agtggcttat
    25381 aataacagag atcatagaaa aatattgatt gttgatggtc agatagccta tactggtggg
    25441 gtcaatctgg cagatgagta cattaaccac gtcgagagat ttggttattg gaaggatagt
    25501 ggaattcgct tagacggact agcagtaaaa gccctgacac gcttattttt gaccacttgg
    25561 tacattaatc gaggagaaat tagtgatttt gatcaatatc atttagaaaa tcattctatc
    25621 ccgagtgacg gtttaaccat tccatacgga agtggaccca agccaatttt tcgagcgcag
    25681 gtagggaaaa aagtttatca gagtttaatc aatcaagcaa cggaatcggt ctatattacg
    25741 acaccttatt tgattataga ttatgattta acagagacaa tcaaaaatgc agctatgaga
    25801 ggggtcgatg ttcgaattat caccccttac ataccagata agaagttcat tcagttagtc
    25861 acgagagggg cttatcccga ccttctttct gctggtgttc ggatttatga gtatagtcca
    25921 ggttttattc atagtaagca gatgttggta gacgaagatt ttgcggtggt ggggacaatc
    25981 aatctcgact accggagctt ggtacaccat tatgaaaatg cagtcttact ctataaaact
    26041 ccttctataa tggaaatcgc ccgagatttt cgaaatatat ttgcagattc tcaggaagtc
    26101 tatcctcatt ctatcaaaac gagctggtat caaaagcttg taaaagaaat cgcccagcta
    26161 ttcgccccta tcttataaga aatctagaac ttaggataca aaccagacct atttttcttg
    26221 tcttttacga atagaaagaa agaggagggg aattcatgct aactaaggaa gaagtgaatg
    26281 atatgattga gttcaaacag acacatttac accgctttcg ggaaattgaa acctttgtga
    26341 aactatgcaa aaaatcactc aaacagccat cgcaagctga caatcctagg actttttgat
    26401 atactaagac agataaattg aacaggagaa acgatatgag tgtgtatggt agagtagaag
    26461 aagttcataa ggagaatcgt gaacctctag aataccaaat cgaacaagaa tcgcatcatc
    26521 gtgaatcaag tcgtcttcct ttggtgaaaa ttttactatg gagtacgctt gtaacgggga
    26581 taactctagg agtaccgcta ttactcgact taatgagtgc acaagaagtg caggattttt
    26641 atgcaggttg ggcgcttcat cagacaggga agatttacag cgactattat ggaagtcaag
    26701 gtttgcttta ttatttgctg acttacgtga gtcagggcgg atatttcttt gccatctttg
    26761 agtggttagc cttggtagca ggaggatttt tcctttttag atcagcggac accttgacag
    26821 agcaaggaga ccaagctgga catctggtga ctatttttta catgctagtt acaggtcttg
    26881 cttttggtgg aggctatgcg actcttttag cgcttccttt cttattcgca gcctttagtt
    26941 tagttgcggc ttacctaagc aatccaagcc atgataaggg atttgtacgg attgggctag
    27001 ctttggcagg cggatttttc tttgctccct tatcatcgct cctgtttatt gctgtagtga
    27061 gtttaggctt gttggtcttt aaccttgggc atagacgttt tgtgcatggg ttttatcagt
    27121 ttcttgcagt ggctttaggt ttttcacttg tcttttatcc aactgcctac tatagtgctg
    27181 caacaggaag ttttggggat gcgattagtg gtattcgtta tcctattgac agtattcgct
    27241 ttgattttac ttctaaaatt ttagagaata tgttttttta tggcttgttg tcccttggtt
    27301 tgggatttgt ggtttgtatc tttttaggtc tctttcaatc caaacccttt aaactatacg
    27361 tcatttcggt tcctgcaagt cttgtggtaa ttttaggttt gattttactt ttcttttcac
    27421 aagagcctct gcacgcttct tatttgatgg tcgtcttccc tgttttccta cttttattgg
    27481 taaccaatat taagagtcaa cagagggggc gtagtgctag aagaagccga agagaaacgc
    27541 cagttagcct atggagtcgt ttcttcaaag gaaatctata tctgctagtt tttgggtttg
    27601 tctatctttt gtctgttcct tttttgatga agtttgtcct ttatccagta ccttatcaag
    27661 aacgtaatcg tcttgctgat ttggtaaaag aggagacaaa tacggaagat gctatctatg
    27721 catgggatga tactgcgact ctttatcgta agagtgagcg cttgtcgcca tcggcgattt
    27781 tgtacccgtt gcactataca gcaactgaag aaaatcgtaa taagttactt aatgacttga
    27841 aagaaaaaca acctaaggtg attgtggtaa atgacaaggt ggtagtctgg tctgaagtgg
    27901 aaacactctt aaaagaaaat taccaacaag taaagactga ttactcagag tttaaagtct
    27961 ataaaattaa ataaccaaat caatatcttg tgtattttta aaaattttag gatttttaac
    28021 acaagatatt gatttttctt tttagagtgg tataatactt tttagaaaga acattttaga
    28081 aaagagcatg catatgattg cactagaaga aaaaattaca attttgccaa ctctcttcgt
    28141 cgagaaacga gatgggagac gtgttgtatt tgatgtggac aagattgaca aggctctcca
    28201 caaggcggct gacaaggtta tggatgtgac acccctggtt gaaaaacgcc tcaatgatct
    28261 gactgagcga attattacag aaattcatag tcgctttcca cagggaatta agatttacga
    28321 aattcaaaat atcgtagaac atgaactcct tgaagccaaa gaatatgcac tggctgagga
    28381 gtatattact tatcggacac agagggattt tgagcgctca aaagcgacgg atatcaactt
    28441 tagtattcat aaacttctca acaaagacca gacagttgtc aatgaaaatg ctaataaaga
    28501 cagtgatgtc tttaacactc agcgtgattt gacagcaggg attgttggga aatcaatcgg
    28561 actgcaaatg cttcctaagc acgtagccaa tgcccaccaa aagggggata tccactatca
    28621 cgatttggac tacagtccct atacccctat gaccaactgc tgtttgattg attttaaggg
    28681 tatgttggaa aatggtttta agattggaaa tgcagaggta gagagtccca agtctatcca
    28741 gactgcgaca gcacagattt ctcaaatcat tgccaacgtt gcttctagcc agtacggtgg
    28801 ctgttcagct gaccgtatcg atgaaatttt ggcgccttat gcagagaaga actatcaaaa
    28861 acatctcaaa gatgcagaag agtgggtatt gcctgaaaaa cgggaagatt acgcttggaa
    28921 gaaaacgcaa aaggacatct acgatgccat gcaatctctt gagtatgaaa tcaatactct
    28981 cttcacttca aatggacaaa caccttttac ttcgctaggt tttggtctgg gaaccagtcg
    29041 ttttgaacga gaaattcaaa aagctatttt aaacattcgc atcaagggtc ttggttcaga
    29101 acaccgtacg gctatctttc ctaaacttat tttcactctg aaaagaggcc ttaatttaga
    29161 ggaaggaact cccaactacg acatcaagca gttggctctt gagtgtgcaa ccaaacggat
    29221 gtatccagat gttttatctt acgataagat tgttgacttg acaggatcct tcaaggtgcc
    29281 tatgggttgc cgttctttcc tccaaggatg gaaggatgaa aatggtgtag aagtcaattc
    29341 aggtcgcatg aatctgggtg ttgtgacggt taatctgcct cgtattgctc ttgagtctga
    29401 aggtgatatg aataagttct gggaaatctt caacgagcga atgaatatcg cagaagatgc
    29461 tcttgtttac cgtgtcgaac gcactaaaga ggcgacacca gcgaatgctc ctatccttta
    29521 tcagtacggt gcttttggcc atcgtctagg taaagaagaa agtgttgacc agctctttaa
    29581 gaatcgtcgt gcgaccgttt cgctgggcta tatcggcttg tatgaagtag cgacagtttt
    29641 ctttggtaac agctgggaaa gtaatccaga tgctaaggaa ttcacgctag acatcattca
    29701 cgatatgaaa cgccgtgtag aagagtggtc agaccaatat ggctaccatt tctctatcta
    29761 ctcaacacca tccgaaagtc tgacagaccg tttctgtcga ctagatatag acaagtttgg
    29821 ctctattcct gatatcacag acaaggaata ctacaccaac tctttccact acgatgttcg
    29881 taaaaatcca acaccgtttg aaaaattgga ctttgagaaa gtctatccag aagcaggtgc
    29941 gtcaggtggt ttcatccatt attgtgagta tccagtcctt cagcaaaatc caaaggcctt
    30001 ggaagctgtc tgggattatg cttatgaccg tgtaggctat ctaggcacca atactccgat
    30061 tgaccgttgc tacaagtgtg actttgaagg ggattttgaa ccaactgaga gagggtttgc
    30121 ttgtccaaac tgtggcaata gcgaccctaa aacagtagat gtggtgaagc gaacttgtgg
    30181 ctacctaggt aatcctcaag caagaccgat ggtcaacggg cgtcacaagg aaatcgctgc
    30241 gcgtgtcaaa catatgaatg gttcaacgat taaaatagct gggcatcaag taacagatta
    30301 gaaagaaatg aaatgggaaa atatcaacta gacgataagg ggtgcgcaca agtgacccgt
    30361 tatcacgaga aacactctaa aggtggagct ggtaagaaag aacgcttgct tagcttcaga
    30421 gaacaatttt taaacaagaa caagaaaaaa taaaagtgag agccagctct cgcttttctc
    30481 atagtgggag gtaaggatgg aattacgcag accaagatta gcggataaga aagctgtttt
    30541 agatatgatg acagagtttg aaaaatttca gtcgcctcac gacggcggtt tctgggatac
    30601 agagaacttt gtgtatgaag actggttaga aagcaatcag gaacaggaaa tggggattaa
    30661 tctgcctgaa ggatgggttc ctgcaattca gttagtggct ttttctgaga aaggtcaagc
    30721 agttggattt cttaatctcc ggttgcgcct cagtaacttt ctactagaag aaggtggcca
    30781 cattggctac tccattcgtc catctgaaag aggcaagggt tatgcaaaag agactctccg
    30841 tcagggcttg caagttgcta aggaaaagaa catcaagaaa gctctggtga cctgtagcgt
    30901 gaataatcct gctagcagag cagtcattct agcaaatggt ggaatatttg aggatgctcg
    30961 caatggagtc gagcgttatt ggatagaggt agcgaatgaa taatccaaaa ccacaagaat
    31021 ggaaaagcga ggaacttagt caaggtcgta tcattgacta caaggccttt aactttgtgg
    31081 acggcgaagg cgtgcgtaac tctctctatg tatcaggctg tatgtttcac tgcgagggat
    31141 gttataatgt tgcgacttgg tcttttaatg ctggcattcc ctatacagca gaattagaag
    31201 agcagatcat ggcagatctt gctcagccct atgttcaagg tttgactttg ttgggagggg
    31261 agccttttct taatactggg attctcttgc cacttgttaa gcggattcgg aaggaattgc
    31321 cagacaagga catctggtcc tggaccggct acacttggga agaaatgatg ttggaaactc
    31381 cagataaact ggaattcttg tcactgattg acattcttgt cgatggaaga tatgatcgaa
    31441 ctaagagaaa tcttatgctc cagtttcgag gttcatctaa ccaacgaatt atcgatgtgc
    31501 aaaaatcgct caaaagtggg caagtagtga tttgggacaa gctcaatgac ggaaaagaaa
    31561 gctatgaaca ggtgaagaga gaatgaagaa aaaatgaaga aaaaagactt agtagaccaa
    31621 ctagtctcag agatcgagac ggggaaagtc aggacactgg gaatatacgg tcatggagct
    31681 tcaggtaaat caacctttgc acaggaattg taccaagctt tagattctac tacagtaaac
    31741 cccaattat
//
LOCUS       DAVIME010000024        31274 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVIME010000024 DAVIME010000000
VERSION     DAVIME010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31274
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.024"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(79..1425)
                     /gene="glnA"
                     /locus_tag="VV588_001168"
     CDS             complement(79..1425)
                     /gene="glnA"
                     /locus_tag="VV588_001168"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU7083521.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTVIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(1462..1818)
                     /gene="glnR"
                     /locus_tag="VV588_001169"
     CDS             complement(1462..1818)
                     /gene="glnR"
                     /locus_tag="VV588_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU7083522.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(1895..2422)
                     /locus_tag="VV588_001170"
     CDS             complement(1895..2422)
                     /locus_tag="VV588_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU7083523.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(2558..3754)
                     /locus_tag="VV588_001171"
     CDS             complement(2558..3754)
                     /locus_tag="VV588_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU7083524.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(3844..8754)
                     /locus_tag="VV588_001172"
     CDS             complement(3844..8754)
                     /locus_tag="VV588_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU7083525.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGKWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNKVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENTEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            9047..10690
                     /locus_tag="VV588_001173"
     CDS             9047..10690
                     /locus_tag="VV588_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU7083526.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKVAEKGHKTEEAINTID
                     EQLTRYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFS
                     DAALKELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRL
                     NKGECSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(11249..12856)
                     /locus_tag="VV588_001174"
     CDS             complement(11249..12856)
                     /locus_tag="VV588_001174"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU7083527.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(13246..13833)
                     /locus_tag="VV588_001175"
     CDS             complement(13246..13833)
                     /locus_tag="VV588_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU7083528.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(13961..14272)
                     /locus_tag="VV588_001176"
                     /pseudo
     CDS             complement(13961..14272)
                     /locus_tag="VV588_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(14170..14582)
                     /locus_tag="VV588_001177"
                     /pseudo
     CDS             complement(14170..14582)
                     /locus_tag="VV588_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14610..15260)
                     /locus_tag="VV588_001178"
     CDS             complement(14610..15260)
                     /locus_tag="VV588_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU7083529.1"
                     /translation="MKDKQTFLMKGSFALLLFVILGYMVKFYPETLVGFDQSIQTAIR
                     GDLPDYLTILFRSLTHLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASFCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(15250..15813)
                     /locus_tag="VV588_001179"
     CDS             complement(15250..15813)
                     /locus_tag="VV588_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU7083530.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(15978..16212)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16266..16769)
                     /locus_tag="VV588_001180"
     CDS             complement(16266..16769)
                     /locus_tag="VV588_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU7083531.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(16962..17792)
                     /locus_tag="VV588_001181"
     CDS             complement(16962..17792)
                     /locus_tag="VV588_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU7083532.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(17777..19459)
                     /locus_tag="VV588_001182"
     CDS             complement(17777..19459)
                     /locus_tag="VV588_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083533.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNLSIS
                     KGQVQLQNELAKETPALQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(19570..19818)
                     /locus_tag="VV588_001183"
     CDS             complement(19570..19818)
                     /locus_tag="VV588_001183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083534.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(19825..20373)
                     /locus_tag="VV588_001184"
     CDS             complement(19825..20373)
                     /locus_tag="VV588_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU7083535.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(20388..21236)
                     /locus_tag="VV588_001185"
     CDS             complement(20388..21236)
                     /locus_tag="VV588_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU7083536.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            21424..22773
                     /gene="trkA"
                     /locus_tag="VV588_001186"
     CDS             21424..22773
                     /gene="trkA"
                     /locus_tag="VV588_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU7083537.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIETKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            22777..24216
                     /locus_tag="VV588_001187"
     CDS             22777..24216
                     /locus_tag="VV588_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU7083538.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(24341..26020)
                     /locus_tag="VV588_001188"
     CDS             complement(24341..26020)
                     /locus_tag="VV588_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU7083539.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(26090..27502)
                     /gene="lacG"
                     /locus_tag="VV588_001189"
     CDS             complement(26090..27502)
                     /gene="lacG"
                     /locus_tag="VV588_001189"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU7083540.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKYNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(27512..27856)
                     /locus_tag="VV588_001190"
     CDS             complement(27512..27856)
                     /locus_tag="VV588_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU7083541.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEAYGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(28024..29910)
                     /locus_tag="VV588_001191"
     CDS             complement(28024..29910)
                     /locus_tag="VV588_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU7083542.1"
                     /translation="MVIRVFDKQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRRDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKAFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRNYEELIEEYFSALYGENWQSVVEYLEKL
                     SIYSSCDYFNAIGSRQSDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWKNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(29912..31234)
                     /locus_tag="VV588_001192"
     CDS             complement(29912..31234)
                     /locus_tag="VV588_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU7083543.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
BASE COUNT         9296 a         6933 c         5546 g         9499 t
ORIGIN      
        1 ttaagggtta taggtatttg atggcttaga ctgctgtgtg actgtttacc cacaggcaat
       61 ctttcttcta tattagtatt agtaaaggtc taaataatta tcaatttccc attgtgaaac
      121 gaaggttgca taacttgccc attcgattcg tttggcttca aggaagctag tgtagatgtg
      181 atctccgaga gcagctttaa ccacttcatc ttctgtcaaa gctttcaaag cgttgtgaag
      241 agttgatgga aggtctgtaa taccagcttc cttgcgctct tctgctgtca tgatgtagat
      301 attttcttcg ataggagctg gtgcttcgat tttattttca ataccataca aaccaacttc
      361 caaaagaaca gccatagcaa tgtaagggtt cgccattgga tccactgaac gcaactcaag
      421 acgagttccc ataccacgtg aagcaggtac gcgcacaagt ggcgaacggt tacgaccagc
      481 ccaagcaatg taaacaggcg cttcataacc tggaaccaaa cgtttgtatg agttaactgt
      541 tgggttcatg atgacagtat agttgtaagc atgcttgatc aaaccgccta ggaaatggta
      601 agctgtttct gacaactgca ttccttttgg atcatttgga tcaaagaagg cgttatttcc
      661 ttctgcatca aacaaggaca tattacagtg catacctgat ccagcaatac caaattttgg
      721 cttcgccata aatgttgcgt aaagtccgtg tttgcgagca atggttttaa caacaagttt
      781 aaagatttga atcttatcac aagcacggag aacttcatcg tacttaaagt caatctcatg
      841 ctgtccaacc gcaacctcgt ggtgactcgc ttctacttca aatcccattt tggtcaagac
      901 attcacaatc tcacgacgtg tgttgtccgc aaggtcagta ggtgccaaat caaagtagcc
      961 acccttgtca ttcacttcaa gtgttgggtc cccattttca tccaacttaa ataggaagaa
     1021 ttctggctct ggaccaaggt tgaaggattt gaatccaact tcttccatgt gacgaagagc
     1081 tcgtttcaaa ttaccacgag ggtcacccgc aaatggttca ccttctgttg tataaacatc
     1141 acagatcaga cctgcaacac ttccattttc atctccccaa gggaagactg tccatgtatc
     1201 caagtccggg tacaagtaca tatccgactc attgatacgt acaaaacctt caatagaaga
     1261 tccatcaaac ataaccttgt tcgacaagac cttatctaac tgttcatctg tagcaggaat
     1321 ttcgacgttt ttcatggttc ccaaaatatc tgagaacata agacgaataa aggtaacatt
     1381 tttttccttg acttcacgac gaatatctgc agctgtgatt ggcataagtt ttctccttaa
     1441 tctatgacta cttgcggttg cctaaccgcg accaaaaggt gactgtactg aagcaaaacg
     1501 cccctgttgg aggagttcat tgtgaagtgc acgacgtact tcagtctgac taaccgcttt
     1561 cttggatttc gcttcacgtt cagcatattt tttcttaatg gcagcgatat tataaccttc
     1621 agagatataa tctttgattt caagcagacg atccatgtca ttcaaggaat acatgcgacg
     1681 atttccttcg tttcgatcgg gcttgatcaa ctcttgatct tcataataac gaatctgacg
     1741 cgccgataga tcggtcaact tcataacact gccgatagga aaaacagcca tatttcggcg
     1801 aaattctttt tccttcattt acaatttcct tctttctgtc tattatagtc taaaaaaaga
     1861 caaacgtcaa ttgataatgt tataaaatgt aacattattt ttcttttttc tctaaaaaga
     1921 gacgaatacg atcaatatcg taatttacga taattgcgac aaaaactccc ataaacgttt
     1981 ctgatacacg cacaaacacg tacgaaattg tctcaccact tggaattgat agggtaatga
     2041 ttaacatagc tgctacacca ccaataaccc ctgctttgtt attcatggct acatttgtca
     2101 taatggttaa catggtgcag attggaacaa ctaccaaggt cacccaaaag gcttcgtgga
     2161 aaaaggtatt taataagaag aagaccaagg catagagtcc accgatacta tttcctagaa
     2221 tacgcgaagt cccaaaatga acactctcat caaaactctc cctcaggcta aaaacggctg
     2281 tcaaagcacc aatttgaaga cctttccagc caaaaaagcc aaaaatcaag agaactagaa
     2341 aaacagcaat acctgtttta aaggttcgca taccaagttt gaactgggat ttatcgaatt
     2401 tatatttttt aaaataactc ataatctcaa ctttctattt ccattttatc ataaatcggt
     2461 gatttttatg agtaatagtt gagaggaagc gtttttattt taagcaaaag aaaagaggaa
     2521 ctttcatccc tctcttcttt gatttgttta taaaatctta tttttctgtc aaggctgcaa
     2581 gtcctggaag aaccttacct tcaagaagtt ccattgatgc tccaccaccc gtactaatcc
     2641 atgagaactt gtctgcacgg ccaaggttaa tcgctgcggc agctgagtca ccaccaccga
     2701 tgattgattt aactcctggt tgtttcacga tagcgtccat cacaccgatt gtaccagctt
     2761 ggaaatctgg gttttcaaat acacccatag gtccgttcca tacaactgtt ttggcaccag
     2821 tcaaagcttc gtcaaatttg gcgatagatt ttggaccgat gtcaagacca aggaagcctt
     2881 cagaaactgc ttcaccttca gtgtcacgca cttcagtgta accagcaaat gcgttagctt
     2941 cttttgagtc aactggcaag atcaatttac catttgcttt ttcaagaaga gctttcgcaa
     3001 catccaattt gtcttcttct acaagtgagt taccgatttc gataccttgt gctttgtaga
     3061 atgtgtaagt catcccacca ccgataagga ctttatcagc tttttcaagc aagttttcga
     3121 taacaccgat cttgtctgaa acttttgaac caccaaggat agccacgaat ggacgttctg
     3181 gagtttcaac tgcttcttgg atgtaggcaa tttcgttttc aagaaggaaa ccagcaactg
     3241 ctttttcaac gtttgctgag ataccaacgt tagatgcgtg tgcacggtga gctgtaccga
     3301 atgcatcgtt tacgaagata ccatctccaa gtgatgccca gtatttacca agttcaggat
     3361 cgtttttaga ttctttcttg ccgtcaacat cttcgtaacg agtgttttca accaagagaa
     3421 cttgtccatc ttcaagagcg ttgattgccg cttccaattc agcaccacga gtgacacctg
     3481 ggaaaacaac atcttgacca agttttgctg ccaagtcagc tgctacagga gcaagtgatt
     3541 taccagcttt atcagcttct tctttcacac gtccaaggtg agagaaaaga attgcacgtc
     3601 caccttgttc gatgatgtac ttaatagttg gaagagctgc tgtgatacgg ttatcgttag
     3661 tgattacgcc atctttcaat ggtacgttga agtcaacacg aacgaggact tttttacctt
     3721 tcaagtcaac gtctttaaca gtaagttttg ccatgttaca aaaactcctt tatttatttt
     3781 attcgaaact attatatcac actttggaaa tataaggaaa gatttcacaa gatttttcga
     3841 tatttaatct ttatcttctc ttttccgtct caaggtcaag gctaaactag caagaccaag
     3901 gctggctaag cctgctatta gggcttcatt agcatcagct gttcctgtat ttggcaattg
     3961 tttgcttgct tcttctgatt taactgctgt attttgagct ggtttttcct gtgtagctac
     4021 tactgctggt actgttttta cttttgttcc aatttcaaca atttctggaa tcgcttcttg
     4081 gatgacttct gttgaacgaa gacgacgctg accgttttca tcaacttcaa agacatgtct
     4141 taacagtcca tctcgtccct gtatgatgac tcgttgttcc ccaactagca tctcagtatt
     4201 ttcatgctct tgacgatgaa aggcaacctt ttcctcttga acttccaatt taggagcctt
     4261 ttgttgatca gaagccggtt gataagtagg ttttggaagg actttgtttt gtggtgctgg
     4321 tttagcaggt tgtggttttt cagcagattc ataaacaaag gcataatgag taaagtgtgg
     4381 tgctgtaaag ataacatgac tatccgtttg ttcaaaagcc aattctactg cctctttgcc
     4441 ttcaggtaag aaaaatactt tcttaacttt cttatctttt tcaattggga ttttcacaat
     4501 agaagcgtaa gagagatcaa catcttgacc tttttcatcc aaaccttcta tttcaaagac
     4561 atgagcatct tctccagcaa agtatttctt ctcttcagca cttgcttgaa cacgctctac
     4621 tttcaaaccc ttgatgacag tcttctcttt atttgagaag tgtacttcaa cacctgtttt
     4681 actatcagaa aagactgctg gcttgtcttc tttcaataaa gcaaccagat cttttagact
     4741 ctgtttcgct gttgcaagct cttctggact caaatctact ttttcaacca aggccttgtt
     4801 tttctcaaga agcggagcta gggcagaacc tgaaggatgg tttggtttgg cagccaagag
     4861 ttcttgaacc tcacctgtta agcgatcaag ttctgtcttt tcttccttaa atttctcttg
     4921 accattcaga gctttatgag cttctgtcaa tttattaagt cggtcattga cttgatcttg
     4981 ggtgctagtt tcatggtctt tcaacacttg ttcggccgct tcaattgctt tcaagaaagc
     5041 ttcttttact tctggtgaag caaagttata gaccaccttg ttcttagcag cttcaacttc
     5101 tgctaatttc tgtttgaggt actcatcgtt caatgctgct tttggagata ccaaaacatc
     5161 aaagttgact tcatgacctt ggtaacgaag cgtcaaggtt tgacgaccag tcttttgagc
     5221 atcgtaacca gaaatttcaa ctccctcatc agtaaaggaa tgttcttcca tggtgtcatt
     5281 gctataagcc actgcaaagc gtccttcaga caagtctaag ctatcaccaa ctaggtaatc
     5341 ttttttcggt tcctgactta cttcaattcc caaaatagtt ttcggacttg cttcgtcttg
     5401 gccagtgaca gtcactgaca aattagcatt tactggttgt cccaaatatt ggagagtaag
     5461 attctgttct cccttatgat gcgtatcaaa acctgatact gatacacctg cgtgagttag
     5521 gcgaatgagt tcgtcctcag ttcctccttc atactgaact cgaagaacac cacctctaag
     5581 gtccaaatcc tccccttcgg cgtagcttgt tttcttaggt cctgtttcta ggctgactga
     5641 cttgattctt ctgtcatctt ttggaacgga aactgctagg acattactaa tttccttgcc
     5701 tggcaactgg gtacgataat aaagaagacc agattgattt gtcaaatcca atggtgcact
     5761 tgctaggtct cctccaactt cgctcttcaa ggttgcgagt ggagtttgag aatttggatt
     5821 atcataaacg gtaatagttg ctccagccgg tacatctgca aagccaactt gtaccttgtt
     5881 attgcctaga gaacgggctg cagccttggc catcggaata ttgacactct cagtatcaag
     5941 cttttcatac attttccagt tatagatacg aatagccttc catggagttc cattgtcaga
     6001 agtgacaaca ttcaagcgcc agtcttgagc agtgattggt ttatcaagag tgatatctgt
     6061 cacgtgtgct ttgttgccac ggacttcctt agctagcttc cacttaccat ctgcatcttt
     6121 ataataaagg tcaaagtctt tggtgttcat caagccatcg ttaacagact caccaccagc
     6181 ccctgcatga tccatgaccc atctaacaac ggtacgtggc ttggtcaaac gaatatccac
     6241 actaccactc aactgagctg aagaccattt atctgacaag ctagtaatgg taccgttcaa
     6301 cataccttca ataccttctc caccttctgt atctgggaag gtacttccga taacagtagc
     6361 ccctggaacg atgttttctg ctagaggtct tggaagactt gtgtcttgga cagtcatccc
     6421 ccactcaaag gttgtggttg cagcttctga acgaactcca tttttaccga ctgctacaac
     6481 cttcagttct tgagttgtac cctgagcact tgctgagcgg ctaacttttg gtagataaat
     6541 agttgtagaa gatgagccag ttagtaattt ccagctgtct ccatcttttt cataaacttc
     6601 atagaaatct gcatccttgt tgcctttaaa ttgcacaact gcttccgctt cttgggcatt
     6661 tttaagagat tgtttcacta cagaaaagct tgtcggcgat tgtggctctt ggtgattgtc
     6721 cgagatagtt aattgtccta ggttaaactg ataatctttt acagcacctt catgctcgaa
     6781 aaatagtttg actgcataga tggttttacc cgctagtgag ctaagatcaa attcttcatt
     6841 tgtccagttg tcagaaaggg ttagctcttt ccatgcatct gcatcatcga atttgtagtc
     6901 tggagttgta gagaatgcca tataaacttt agaacctttt cctcccttgt gggcaacacg
     6961 aagtttggtc ttctcagtta cttctaactt agtagaataa agtctcacat cctgatctgt
     7021 cttaccggct acatcaccag agaatttaag ggaatttccg ccattatagg catctgtaaa
     7081 atcatattct gcacgaagtt tttcccctgt tgaagtctgc caccagcgcc atgttggaag
     7141 aacacctgat actgaacgat aattccactc agaatcctta gaaaccttac catctacgaa
     7201 ccatttttta ccatgacctg tattaaaaga agtagtaaaa gtattaccta ccgctggcgt
     7261 acggtccgca actaggttag caataccata ccaatctttg tcacctggtt tttgaccagt
     7321 agggtctcct tgataacctg taaagaagat atcttcattt ttatgataat cttcaccagt
     7381 ttttcctaaa cttgtaatgg tatctggggc aaataaacca agagaaaggc gcaatttccc
     7441 attttcgtct aaaatgtcat tccacttaac ctttgtcttg taggaaccac cctgttgcaa
     7501 ttccaaacct gcaaatacat cataaggatt acgaccaatc cagttggcag ttgcaatagt
     7561 gtaatcattt ttagccttat cccagttaaa gttagcaaag aagttatctg ccggaacctt
     7621 atctccttct ggttgcatga attggtagtt gtattctccc aaaccatctt gatggtaacg
     7681 tccatagtta taggtcatgg catcatacca agaatacttg attggatggt ttaccttagc
     7741 agcatattcc ttgctataga gcataaactg gcgcatcttt tctccaagag gtttaaccaa
     7801 atctccagtt gtttcttggt tgatgaaata gccatcatag ccataatact tggccatgtc
     7861 taccaattta cgggcaattg ggaagctacc atctgcgtct tgcttcaaag cttcagcaaa
     7921 tctttcttga tctgcaatac tattagacca gttgaagaag agtgtaccgt atacaggaac
     7981 cccgttacgg tgacctgcat caataacgtc aggagttggt acgagacctt cccagaagac
     8041 cattgaatct agatattgcc aatagtcaaa agcataggcc ttgaactctt ctccaccaac
     8101 agaagcatgg tcttttgctt tagaattggt gtttgataag gcttgaactt ttgcttcctt
     8161 gctagctttt tcattgacta aatgacctgt ccgacgtgaa gcgaggacaa cagatccgcg
     8221 gttaatagca tcatcttcac gagcacctgg ttcccatttt aacaattctt cccaagaatt
     8281 aaatttgatt tcctttggtt ttaatgtttt ttctgtattt ttagggacat ctggctggac
     8341 ttctttttca gtcttattag cttctgctgc tggcttagac tcatcccctt ggttagttgc
     8401 ttcgggcttt gcttctgttt ccttgtcaga cttaggtttt gcttctgcag atggtgtttc
     8461 tgcaaccacc tcacctgctt tttcctctgg tttagctgcg ctagctgctt ctgccttttc
     8521 tagcttgttt tctctagcat gttccccttc attctgctta tcagcttcat tggtcgaatg
     8581 ctcactctct cctgaaacaa gctctgtatt agctccgcta ttttcaggaa ctgcagtttc
     8641 ttcagccaag gctggaccag caaataaaac agcaccaatc atcagcgagc aggctcctac
     8701 tgataactta cgaatactgt aacgacaacg tctttcaaaa aatggattct tcattttctc
     8761 ctcctaaaag attgattttg ttgttttaaa gaaagcgctt tatattctgt agttttttat
     8821 caaactctag aaccatgata atcacatttt tatcctaaaa catttttaga caaaaaacaa
     8881 taactgtttg cacaaatcta aaataaggtt aaaaactctt aaaaataata cacttatcaa
     8941 ttataatttt cttttacaaa cttgacatta acacttgtta gatttacttt tatcctttaa
     9001 aatagaatag gagatattcc gcgattattt ttcggaggaa aaagaaatgt ccattaattg
     9061 gcaggaaatt ttatttcact ttttaggtgg tctggggcta ttcttatata gcatcaagac
     9121 catgggagac ggtttgcaac aagctgctgg agatcgcctt cgtttttaca ttgacaaata
     9181 tactagtaat cctttctttg gagttctggt tggtattggg atgactgctc taattcagtc
     9241 tagttctggt gtaacagtta ttacagtcgg cctggtcagt gccggtctct taaccttacg
     9301 tcaggctatc gggattgtca tgggtgctaa tattgggaca actgtcacat cctttctcat
     9361 cggttttaaa ttaggtaact atgccctacc tatgctcttt atcggtgccg tctgtctctt
     9421 ttttacgaaa aatcggacag tcaataatat cggacgcatc ctctttggtg tcggtggtat
     9481 cttttttgcc ctcaatctca tgagcggcgc aatggctcca ctcaaggatt tacaggtctt
     9541 taaggactat atgattgagc taagtaagaa tcctgttttg ggtgtctttg tcggtaccgg
     9601 cttgaccttg ctaattcaag cttcttcggc taccattggg attttacaaa acctctacgc
     9661 cggcaatcta attgacctac agggagcttt gccagttcta tttggtgaca atatcgggac
     9721 aaccattaca gccatcattg cctctttagg ggctaatatt gcagctaaac gggtagcagg
     9781 agctcatgtt gccttcaacg ttatcggaac agtcgtctgc gttatttttc tagttccttt
     9841 tactgtcctg attcattggt ttgaagctac gctaaatcta gcaccggaaa tgaccatcgc
     9901 ctttgctcac ggaaccttta atattaccaa caccattgtc caatttccat ttatcggagc
     9961 tctggcttac tttgtaacca agattattcc tggagaggac gaggttgtca aatacgaacc
    10021 cttatatctt gatgaacatt tcatcaaaca agccccatct atcgctctag gaaatgctaa
    10081 aaaagagctc ttgcacttag gaaactacgc tgctaaagcc tttgaccttt cctataagta
    10141 catcattgac ttggatgaaa aagttgctga aaaagttgct gaaaaagggc ataaaaccga
    10201 agaagcaatt aacaccatcg atgagcaatt aacacgttat ctcattgccc tttcaagcga
    10261 agctctcagc caaaaagaaa gtgaagtgct caccaatatc cttgattcct cccgtgattt
    10321 ggaacggatt ggagaccaca cggaggctct actcaatctg actgactatc ttcaacggaa
    10381 aaatgttgaa ttttctgatg ccgccttgaa agaattagag gaagtttacc gccaaactag
    10441 tgactttatc aaagatgctc tggatagtgt ggaaaacaat gatattgaaa aagcacgcag
    10501 tcttgtagaa cgtcatgaag caatcaataa gatagaacgt gttctcagaa aaacccacat
    10561 caaacgcctc aacaaaggcg aatgttcaac acaagctggg gtcaacttta tcgacatcat
    10621 ctcacactac actcgtgtat cagaccacgc tatgaacctt gctgaaaagg tttttgcaga
    10681 acaaatctaa gaaccaagaa gctatccatc ataattggat ggcttcttac tttttcctaa
    10741 gcaagactag gctgaatgaa actgaaagag tattctgcag atatatagta tattgaaact
    10801 agaatagtac acctctattt ctaaaacatt gttagaaatc gatttgactg tcctgatcga
    10861 tttgtcctgt tattatttca ttttactata gtggattaaa ttaaaaaagt ataatgtatt
    10921 gaatctataa cagtacatct tgactgctaa aatatttcta taaattaatt tgactttcct
    10981 tatagagatg ttcacatctt atttcaattc atgatacaat ccagttccta aaactttgct
    11041 agaaattaat ttggctttcc gaattaattt gttcagattt tatttcattt caatatactg
    11101 ataaatccat tcactagcac agggcaagag ggagtcgcta ttgatttcaa cggtagcagg
    11161 tacatacaga ggactcctac ctcagatata ctgcaatatc atcgtatgca aaaaacctct
    11221 gagatttttc tcaaaggttc tgattttgct aattgctgtt ctcaaccgct gcagtaacaa
    11281 aggcagtgta gagttcttct ggtcggtttg gacggcttga cagttcaggg tgatactgac
    11341 aagctacaaa gaatttattt tcaggaattt ccacgatttc taccaaacga ttgtctggag
    11401 aaactcctga aaagacaaaa cctgctgcct caaactgctc acggaaggca ttattaaact
    11461 cataacggtg acggtgacgg cgttgcacca cttcttgatt gtgataagca gcagcagcct
    11521 tagagccacg tttcaactta gacggataaa gtcccaaacg aagggttcca cccatatcct
    11581 caatatcaat ctgatcacgc atgatatcaa tgatagggta ttttgtttct ggtgcaagct
    11641 ctgcagaatt ggcaccttca agacctaaaa cgtgacgagc aaactcgata catgtcaact
    11701 gcattcccaa gcagactccc aacattggaa catcattttc acgcgcatag cggatggctt
    11761 ggattttccc ttctgtacca cgttgaccaa aaccacctgg tacgatgatc ccgtccgcat
    11821 cagacaagag ttctgctaca ttctctgctg tcacatcatt ggcattgacc caattgattt
    11881 taacttctgc atcattgaca tagccagagt gtttcaaggc ttcgaccact gagatatagg
    11941 catcttgcaa ctccacatac ttaccaacaa gggaaatctt aacttgtttc ttgaggttca
    12001 tgaccttgtc caccatggct gaccattctg tcatagccgc tgctggtgcg tctaatttca
    12061 aatgatcaca aacaatttgg tccatccctt gtgcctgcaa gttcagtgga atttggtaaa
    12121 ggtgttcaac atccaacgat tcgataacgg cttctggtgc cacatcacag aactgggcca
    12181 gtttattttt aattccttga ccagctggct cttctgtacg aataaccaac atatttggtt
    12241 ggattcccaa gccacgcaat tctttgacag agtgttgggt tggtttggtt ttcatttcac
    12301 cagcagcctt gaggtaagga agcaaggttg tatggatata catgacatta tccgcaccca
    12361 catctgcctt catctgacga agagcctcta ggaatggcaa ggactcgata tctcctactg
    12421 ttccaccaac ctctgtgata atgacatcag agtcggtcgt tagagcggca cgcttgattt
    12481 tttctttcaa agcatctgtg atatgaggaa tgacttgaac agttgcccca aggtattctc
    12541 cacggcgttc tttacgaaga acttcactgt aaattttccc agttgtcacg ttggaatatt
    12601 tgttgagatt gatatcgatg aaacgttcat agtgacccaa gtccaaatct gtctcagctc
    12661 cgtcatctgt cacaaaaact tccccgtgct ggtaaggact catggttccc ggatcaatat
    12721 tgatataagg gtcaaacttt tgaatggtta ctttgagacc acgatttttc aagagacggc
    12781 ctagactcgc tgccacaatc cctttcccaa tagacgatac cacaccacca gttacaaaaa
    12841 tatatttcgt agacatagat tcctctttct aaaatgctca aggtcttgtt aactacgagg
    12901 ggatatagaa aacaagaccc tactaataag aataatctgg gacgactgca ccagattcac
    12961 aactaatact cttcgaaaat ctcttcaaac cgcgtcaacg tcgccttgcc gtagatatgt
    13021 gttcctgact ttgtcagtct tatctacaac ctcaaaacag tgttttgagc agcctacggc
    13081 tagtttccta gcttgctctt tgattttcat tgagtataaa atacaagaag ataacttctt
    13141 gaaaaaacaa aaatagctcc ctaagaacta gggagccccg acctctaaaa gaggtgccca
    13201 aacaatatga tacctaaaaa taggataatt gtcaatagct aactcttatt cctcgctggt
    13261 ttcagcgtcg tcatctgaaa actcgtcgtc gtcttcgttg agatccacat cttctcccaa
    13321 gtcatctgga gcgatttcgt tgatttctgc atcataagct tccacttcat ttttttcatc
    13381 atctggattt tcatcatcgt atgaaagagc tggatctgct tcgtatgcat cttcgtcttc
    13441 tggatcatct gcattgtagt caatggcatc tgaatcacca tccataaagg cattgacacg
    13501 ttttttctta gcttttggtg ctacttcatc gtcgtcattt tcttcaagag cgatgatttc
    13561 ttcgtcgatt tcgtccacac cataccatga acgaagaccc catttgttgt ccccaagtga
    13621 gatgaagcta ccgtcaaagt tcaactctgt gtagaacaga ggcaaagctt cgcggatatc
    13681 gctgtttgat gttccaaggt agttttgaat ttcgtttaca agatcgctaa aatgcatctc
    13741 atgatcgcga ccacgaagtt ctaatatagc acgcgctacc tcaatcatag atagttcact
    13801 tttttcttgc ccagcaaata cttctaattc caaagcgttt ctcctcattt atactactat
    13861 cgccagagcg aacagactct gacctcattt tatcatttac tctttatttt acgataattt
    13921 tgcggaatag tcaaaggtta agggggagaa agtggcagga ttagactaat tccaatataa
    13981 aactccttcc tttttctgtt gctccatttt ccacaaatcc aagcgacttg aaacacctcc
    14041 tagaagcatg attgtaggtg tagatttcct tgactctcaa ttctttccat ccttttactc
    14101 gagccaattc aatcaaagca cttagaatct tttttccaag tcctcgatgt tggtaagcgg
    14161 aattcccaat cacaatgggg agattatcct gagatagtgt aatatcccca attggaaacc
    14221 attctccctt ctccttgact tcaatccaaa aaagctcacc atgccgatcc aaagaggtaa
    14281 gatatgattt tttaaatcaa aaacagagta aatctttcct cgcaagcttg cgcatagaga
    14341 tgatatagtt catcaccacc atctctatcc cactcagcag aaatcgtatc ccgacctgcc
    14401 aataaagcct gataagccct gtgatgccca tctgtaatca gcaaacaatc tccaaaggca
    14461 agaatactga ttggatcgac ttggtttgtt tctgccgact ggtaaagcat ctgaatatct
    14521 tgcaacttct tttctgataa atatagttga gtcggatgaa gatctactat attgactttc
    14581 atttctttct cctaaaggga attcgatact cacttctgtt tgcctttaaa tcgccattgg
    14641 aagcggagct tgtcatagaa gggaaactcg ataaacaaga ctcccaaacc cacacagaaa
    14701 ctggcaagaa catctgatgg gtagtgaact cccagataga ctcttgatac cagcacactg
    14761 actaggtaga ggccaaggac gatttgtacg atttttctcc agacctgatc tttaatccgc
    14821 tgactaagaa taacaatcaa agtccctacc atcagcgtta cagctagaga atgcccactt
    14881 gggaaggaaa atcccttctc ctccaccaga tgtaagatag ctggtcgtgg gcgctggtag
    14941 atatttttaa aggtcacgat taaaagacct gccaaagcca gatttcccag catgaagaaa
    15001 ctttctatct tccatcgctt acgataaaag acaaaagcta taatgacaac ccaagtgata
    15061 atcactggaa tatcaatcag atgtgtgagg gatcgaaaaa gaatagtcaa ataatctggt
    15121 aagtctcctc gaatggcagt ctgaatcgat tggtcaaaac cgaccagcgt ttcagggtaa
    15181 aatttgacca tatagccaag aataacgaaa agtaaaaggg caaaactgcc cttcattaaa
    15241 aatgtttgtt tatctttcat agtgttttaa ggttggtttc aaaaggacgt acaacaacca
    15301 gaatgaaacg gaaaagatta caccctcaat caagttaaaa ggtaatacca tggtcattag
    15361 gtagttggaa agtcccaaaa tttttccaat atcaaagtta gcaaacttag cgtacaaagg
    15421 aacagcataa acatagttga gaaccaacat ggccaaggtt aaaccaacag ttccagctag
    15481 agagcctagt aggaaacgaa gggttgtccg ttcctttttc caaatcaaag caaatacgat
    15541 gacaaaaact cccaaagcta cgatattcat cggcaaacca atgtaagtat tcactccttg
    15601 gctgttaaga agcaatttca atagtgagcg aagcaagagc actcctagag cagcaggcaa
    15661 atccatgacc accagaccca caaggactgg caagatacta aattcgatct tgaggaaaga
    15721 tgccgctggt aaaagcggaa agtcaaagta catcagcaca aatgagatgg ctgatagaat
    15781 tgcaatggtc gaaagtcgac gtgtgtttgt cataacaggt tcctccaatt ttctataaaa
    15841 tcagaagaag ttggaaagga ttcctctatc tattctcact ttttatatcc caaaagttcc
    15901 ctcttactct attaaagaaa aacaaagcaa gtggttacaa tccggctata aatctatcaa
    15961 aacagacaaa gctattcttt cgtcttctcc catccagact atactgtcgg ttgtggaatc
    16021 tcaccacatc agcttgcgct cgcggacttc tttaaagaga aggaaataga gatttttctt
    16081 ttagactagg cgacaagctg taggcataac ttctggttag gcaaagcttg tcaacaaagt
    16141 ataaaaggaa aagatcattt cctagttaaa gtcaccgccg gtcgggaatc acaccctgcc
    16201 ctgaagactc ttttatcata acaaaaaacg cttgcaagcg caagcatttt gttcattttc
    16261 attttttatt tcaatttatc cacttcatag gtatggacga gctcaagacc tgcaaagttc
    16321 tgctggcgaa gagcctcata gacaatcatg cagacggtat tagacacatt gagactgcgg
    16381 acatgttcat cattcatggg aatacggaga gccttctcag gatgttctcg cataaaatct
    16441 tcaggtaagc ccttgtcttc acgtccaaag agaaaataat ggtcctcgtc agtcgataaa
    16501 tccacctcag aatagacttt ttccgcgaat ttcgaaatca gatagagttt tcccttcatc
    16561 tgagatatga aatcttccaa actctcgtaa aaataaatct ctagcttatc ccagtaatcc
    16621 aatccagccc gcttcatctt gcggtcatca ataggaaagc ccataggctt gatgatgtgg
    16681 aggggagaat tggtcgcagc gcaagtacgc gcgatattgc ccgtattttg tggaatttga
    16741 ggttcaaata atacaatgtg atttgtcatg acttgcttcc tttcaccatt gcaaaaaaat
    16801 agccacactg cccggagtca agctcagcaa acagcgtggt taaggcatcg ttaacttacc
    16861 tcacaacagg tttgaagtaa atcagcgaaa ctactttctt agtataacac tttcagaatc
    16921 attgtcaata gaaatgactt gattttttca attttttcaa gctatttcca agggttgtaa
    16981 aatcgtccct gattctgcaa gataagtagt aaactaacta ctaaaaacaa ggttgccaag
    17041 agcaaggtaa tatagtctcc ttttttcaag gcctgataac tataccatgt gcgttttttc
    17101 tctttcccaa agcggcgaag ctccatggca gtcgcaatgg tatcaatgcg ttctagcgag
    17161 ctaaaaatca agggcgtaat aatgagcaga ttgcctttga ttcgttgcat aagagaagct
    17221 ttcttggata attccatccc acgcgcctcc tgagacatct tgatagtaaa gaattcttcc
    17281 tgcaaatctg gaatatagcg caaggtcagg ctgacagaat aagcaatctt atagggcaca
    17341 ccaatttgat ttaaactgga agcaaactga ctaggatggg ttgtcatcaa aaagataata
    17401 gccagaggaa tggtgcaaag atacttaatg gccaaattta gcagataaaa gagctcctgg
    17461 ctggttagag tgtagacacc gattccctgc caaatcacac ttctctctcc ataaagtcca
    17521 accccatact cgggagaaaa gagatagacc atcaaaacgt ttaaaacggc aaataccgtc
    17581 gcaaaaacgg ctacaaagga aacatcttta aagcgaattt ctgataaata gaggagaaag
    17641 actgaaaaga tggcaatcag caagagcatt ctggtatcat agctaatcat ggccgccaat
    17701 gataccagaa tgaaaaagag aagtttccca gctcctgaca agcgatgaat cacagtatct
    17761 ctatgctggt aaccgattaa tttagcttgc atccctctct cctttctttg taaaatgccg
    17821 ttaaatccag tggatccaca tctagtttct tagccaagtt aaagatggag gtttctttta
    17881 gattggcttt tactaacagc tcaggatcgc tcaacagact ggctggaaca gtatcggcaa
    17941 tcaattctcc atccaccatg acaaggaccc ggtctgaata atccagcatc aattgcatat
    18001 catgggtaat catgacaatg gtatgccctt tttgatgtaa ctcttcgaga aattccataa
    18061 tctcagtata gttcttctga tcttgacctg cagtcggttc atctaggaga ataatttcag
    18121 ctcctaagac caaaattgaa gcaatggtga cacgtttttt ctgaccaaat gacagggcag
    18181 aaataggcca attacggaat tcataaagtc cacagatttt caaggtttca tatactctcg
    18241 tttcaatttc cttctcatcc acacctcgca aacggagccc tagagccacc tcatcaaaaa
    18301 tcatattggt tgaaatcatt tgattaggat tttgtagcac atatcctact cgttccgccc
    18361 gctctgcaac agaatcgcct tttatatcct gtttttccca aagatagcgt ccttccgtct
    18421 gaataaagct acttatagcc ttggctagag ttgatttccc tgctccattt tttccgacaa
    18481 tagcaatctt ttcacccttt ttaatatcta aatgtaggga ttttaaaatc ggtctatcat
    18541 cataagaaaa agatacttcc tctagtctaa agagtgactg caatgctggg gtttcttttg
    18601 ccagttcatt ctgcaactga acctgacctt ttgagataga caagttatcc agattcgcta
    18661 attgttcttc cttgactaaa tccacaccca attgacggag agtggtgaga taaaggggtt
    18721 cgcgaattcc attttgggtc aacaaatcag tcgccagtaa ctggtcaggg ctcccattaa
    18781 aaaggatacg accatcgttt atcaagacaa tccgatccac agggcaatgc agaacatcct
    18841 ccaaacggtg ctcgataata agggtcgtcg tcccctcctc cttatgaatc tggtcaatca
    18901 attcgataat atcctgacct gacttgggat caagattggc gagtggctca tcaaacaaga
    18961 gaatcggact ttcatcaatc aagacaccag ccagactgac tcgctgcttt tgtccacctg
    19021 acaaatcctg agggcgctga tccagtaaag gaagaaggtc cagcttttca gcccatttat
    19081 aaacacgacc tttcatctca tctagggctg tcacatcatt ttccagagca aacgccaaat
    19141 cttctgccac agacaagcca ataaactgcc catctgtatc ctgcaaaact gtgctaacca
    19201 gatgagactt atcatagatg ctcatatcaa aggctgtttg accctttatc aaaaattctc
    19261 catatgtctg acccttgtaa atattgggaa taatcccatt caaacactga cccaaggtag
    19321 atttacctga tccagatggt ccaacaatta agactttctc tcccttgtaa atggtcaagt
    19381 ctatcccttg caaggtcggt tcttgttgtg tttcataccg gaaagagaaa tccttccact
    19441 caattatagc ttctttcatc ttactctctt cattcgcttc ttagacttct attttatcat
    19501 aaatcaagcc cttcttgcag tctctcctat taaaatctta gcgccaaaaa gattcctatc
    19561 ctagcttact tacctaacta atctataaac atcgaaaaag actagttgcc cagccttccc
    19621 catcatttta tactcttcga aaatctcttc aaaccacgtc agcttcgcct tgccgtaggt
    19681 atggttactg acttcgtcag tttcatctac aacctcaaaa ccatgttttg agctgacttc
    19741 gtcagttcta tccacaattt caaaacactg ttttgagcaa cctgcggcta acttcctagt
    19801 ttgctctttg attttcattg agtattagtc ctttttcaaa cttcctgcac gagtttgggt
    19861 tcctgcatag gcaagtaaga gaagagttcc tgcaatagct acagatacac cattggcaat
    19921 tcccgcaaca atcccttgtg caaatacttt ttctgccgct tcttgataaa tcacaacatc
    19981 tccaagtggt gccaagacac cccaaacaag ggcatttgca agtagttgaa tgaggttaaa
    20041 aataagaata tctttccagt caaaaacacc attgatcacg cgaacgtact ttctaaaaag
    20101 tcccacaact aaaccaaaga gtccgctagc gataatccaa gtccaccata gaccataacc
    20161 agcaagagag tccttgattg catgaccaat caacccgaca agcaaaccga taatcggtcc
    20221 aaaaataata gaaagtagcg cttgtaccgc atactgaagc tggatgcttg tatttggaac
    20281 aggggttgga atgttgatca tcccgatgac gacaaagagg gcagcgccaa ttccgacagc
    20341 aacaacttgt ttaattgtaa atttaatttc catactattc tcctatttta tccttctatt
    20401 ttctttattt caatggtcca agatgaaccg acacctacat tataggcctt ggcaaaggaa
    20461 ccttggttga tagccaaacc taaacgatag agagagttga tgtaaaggat gggttgccca
    20521 attctcacat ctgcaaatga tttgccatag acaacctgat tttgatagac cagcatatca
    20581 gcatgataga tggtcacttc aaaacgatca ccaaattctg gttccagctt gtaaaattct
    20641 tcccgtgtga tagaggtcca aagcgaaccg aaacgcacat ccagaatatc aatggctccc
    20701 ttcaccagat gatcttctat gatggtcgct acgactggaa gctctacaat ctgttccaca
    20761 ctgagctctg gccctacttc ctcaaaagta atgtgaccac tggccagttt agcaccagta
    20821 taggcataga catcacgacc gtggaaggta taagaatgct ctgtgttttg acgcctattg
    20881 gccacctcag aaatctcacg aatggctaca atgccaacgt gtttcttgat aaaggaaagc
    20941 gtcccattat ctggcgtgac aatgtattga ttttttgcag tcttggcaac tacactctta
    21001 cgtttcgaac cgacacctgg atcgacaacc gatacaaacg tcgttccctc aggccagtaa
    21061 tccaccgtct gaaagagacg atagctcccc tcaaaaatat tataaggcgt gatatcgtgc
    21121 gtcaagtgat ggatttttaa ggttggagac tcttctaaag ccactccaat catagccgat
    21181 accgcaccat caaccagacc aaagtctgat tgtaatacca gtaaattatt attcatttta
    21241 tctccttgta tatcctttat cataccatat ttcagagaaa gtcgctaata gctatttcaa
    21301 ttggttaggg tatagtttta ccttatagcg aattttcact aaaagctctt gttattagct
    21361 agtaggtgca ttttttcttg aaaaagggta tgatagttac atcatgaaaa agtaggtttt
    21421 attatgaaaa ttatccttgt cggaggggga aaagttggtt ttgccctctg tcgctccttg
    21481 gttgcagaaa agcatgatgt tttgctgatt gagcaagacg aagctgttct caatcatatt
    21541 gtcagtcgct ttgatatcat tggtatcctt ggtaacgggg ccgattttgc cattcttgag
    21601 caagccagcg tccaagattg tgatatcttt atcgccctga ctgagcacga tgaagtcaac
    21661 atgattgcag cagttctagc caagaaaatg ggagctaaag aaactatcgt tcgggtgcgg
    21721 aaccctgaat attctaactc ttatttcaag gaaaagaata ttctcggttt ttctcttatc
    21781 gttaatcctg agctcttggc tgcccgcgct atcgcgaata tcattgactt ccccaacgcc
    21841 ctgtctgtcg aacgctttgc tggtggacgc gttagcctca tggaatttgt cgtcaagtcc
    21901 accagcggtc tttgccaaat gcccatttct gattttcgta aaaaatttgg taatgtcatt
    21961 gtctgtgcga tagagaggga tcatcaaatt atcattccaa gcggtgacat gactgtacag
    22021 gataaagata gaatctttgt cactggtaac cgtgtcgata tgatactctt ccataattat
    22081 tttaaatcac gcgccgtgaa gagccttctc atcgttggag ctggtagaat tgcctattat
    22141 ctattaggta tcctcaaaga tagtcgtatc gaaaccaagg ttattgaaat caatcctgaa
    22201 atcgctagct tctttagcga gaaattccca aatctctaca tcgttcaagg agatggaacc
    22261 gcaaaagata tcctgctgga agaaagtgct caacactatg atgccgttgc gactctaaca
    22321 ggagtcgatg aggaaaatct gattacatct atgttccttg acagggtagg tgtacagaaa
    22381 aatattacta aggtcaatcg taccagtctc ctcgagatta tcaatgcgcc tgatttttca
    22441 agtatcatca cacctaaaag catcgctgta gatacgatta tgcactttat tcgtggtcga
    22501 gttaatgccc agtattcaga ccttcaagcc atgcaccatc tagccaatgg ccaaatcgaa
    22561 accctgcaat tccatatcaa ggaagccaat aaaatgactg ccaaacctct ttctcaactg
    22621 aaattgaaaa aaggggttct tattgcagcc attattcgaa agggcaagac tattttccca
    22681 actggggagg atatgttgga agttggagac aagctcctag taacaacctt gttgccaaac
    22741 atcaccaaga tttatgactt gattgcgagg taagaaatga ataaaagtat gattcgttac
    22801 ctcctttcaa agttactttt gattgaagct gttctcctct tggttcctgt ggctatcgct
    22861 gtctattacc gtgaatcgag ccaagtcttt acagccctct tttcgaccat agggattctc
    22921 gtattgttag gcggttcagg gagtttacag aagccaaaaa atcaacggat ttatgccaag
    22981 gagggagtct tgatcgttgc cctctgttgg atcctttggt ctttctttgg tggtctcccc
    23041 tttgtctttt ctgggcaaat ccctagcgtt attgatgcct tttttgaaat tagttctggg
    23101 tttacaacta ctggagcaag tattttgaac gacgtttcgg ttctcagccg ttccctcctc
    23161 ttctggcgaa gttttaccca cttgattgga gggatgggag tgcttgtttt tgcacttgct
    23221 attatggaca atgccaaaaa tagccaccta gaggtgatga aggctgaggt tccaggtcct
    23281 gtttttggca aggttgtatc caaactaaaa aacactgccc agattctcta tctcctttat
    23341 ctagctctct tctccctctt tgtcatcatc tattatctag ctggtatgcc tctctacgat
    23401 agttttgtca ttgctatggg gacagcggga actggaggct ttaccgtcta taacgacgga
    23461 attgcccact atggcagctc actgattacc tatctggtca gtatcggagt tctggttttt
    23521 ggggtaaatt tcaacctcta ctactacctc atgctccgtc gcatcaaggc cttctttggt
    23581 gacgaagaac ttcgggctta cttggtcatt gtactggttt ctacaggctt gattagcctc
    23641 aacaccctct acctctaccc agggttttca aagagctttg aaatgacctt cttccaggtt
    23701 tccaacatca ttacaacaac tggttttgga tatggagata ttaccaactg gcccctcttc
    23761 tcccagttta tcctcctttt cctcatggca atcggtggct ctgctggatc aactgcaggt
    23821 ggactcaaga ttattcgagg cctcatcctt tcaaaaattg ccaaaaacca aattttgtca
    23881 atcctatcgc cccaccgtgt tttgactctc catgtgaatc aaacggtgat tgataaagat
    23941 acccagcata agattctcaa gtactttgtc atctatgcta tgattttgct agcgcttatc
    24001 tttattgtca gcctagatag caatgatttt ctggtcgtga ccagcgctgt ctttagctgt
    24061 ttcaataata tcgggcctat tctaggaacc acttctagtt tctcaatctt tagtcccatc
    24121 tcaaaaattc tcctctcctt tgcaatgatt gcagggcgct tggagattta cccaatcctc
    24181 cttctcttta tgaaaagaac ttggtctaag agataaaata caaaatccct ctttttacaa
    24241 ttgtgaaaga gggattttta tattaaaaag ggggaacgtt tttaaatcca agcctgtctg
    24301 taagcaaagt tcttactcaa ataaaagatg gaaaaactta ctacacagct tggtaatgct
    24361 ccaatacaaa ttgtaaggct ttacttggat tctttgttaa atgaatatat tccattcctc
    24421 tggtagcaac tatctgaata cctaatcttt ctgcatccac cttcatctct ctataataac
    24481 tccgaacttg tggagccaga ataattaaat cataaacacc cataatatca taatgagctc
    24541 cgtacgctcc tgaattcgca atcactctaa cttctgctaa ttgagcgccc tcgttaattg
    24601 cattggctaa ttgcgcactt gttccagacc ctgcacaaag aaccagtact ttcaactcct
    24661 tactttttat ttcatctaac tcaccaggca ttatttcact tgtctcctcc tctaaaataa
    24721 tatcatttga gcttgcaaca tcttctttca tcagtaactg tctatcatac gctctacaga
    24781 atggcaaata aatcaatatg tcgacaacta aaatcaaaga taaaaataca aaggagatag
    24841 attgaaaatt cgttccaatt aacaatccca agggaccagg aaaggcccaa ggtaactgga
    24901 tataaaatcc attcattcca aagaaatcaa taaagacctt tcctagaaat acattcactg
    24961 gtggagtcat caaaaaaggt acaaaaagat agggattcaa aataactggc ataccaaata
    25021 gaagaggttc attcactgca aataaaacag gagtaattgt agctttacct accgatttta
    25081 attgtttaga ccgcataaag aaaatcaaaa taaatggtac aacaaaggta gcccccgttc
    25141 ctccgatagc agcgatataa tttccgaaat taggcgttaa agaatgataa ggaaactgcc
    25201 catttgcaag aagttgagca ttctcttcca tattgctcag ttgtaaagct gtaacagcag
    25261 gtaagacaat agatggtcca tgaattccaa caaaccaaag caaagcgcac ataaaccaaa
    25321 tcaacatcat agcaggatat gattctgccc ccttaaaaat aggagtcaat agttgttgaa
    25381 atacttgggc aaaaggaaca tctaaactaa accgagatac aatatctaac aaaccactaa
    25441 taagtaaaac aaaagaaaaa ggaaaaatat ctctaaaagc ttgtgatata gccccaggaa
    25501 cttccttagg taaatgaata gtaatgtctc gcttaataca gaatcggtaa acatttacag
    25561 taataaaggc actgacaaac gaagttatca atccttgaga tcctaaatag tttgtcgaca
    25621 aacttgtaga tcccgttttc tcatcaacta caagcgttac agttaataca agatagccac
    25681 atatggccgc caacattgca gaagtatcat ttattacctt tccaggaggc atttttctat
    25741 taacatttcc agccaatgac tttgcaactg tccctgaaac aataacaccc aaaactccca
    25801 tggttagcat atacactttc ctcatccagg caatagctgg actcggtaac tctactccga
    25861 aatttttagg aatcataata ataatcatca aaaagcttga aaacataatt aaaggcatag
    25921 tagcaatgaa tccatcttta atagccatca tataattatt agtagaaatt ttttcaaatt
    25981 tcccttgttg cttttcaatg gcagcgacta acttatccat aaaaactcct cctgtaaaaa
    26041 atttaagctc atagttaaaa tatattaaac atcagtcaaa tcgctaacct taattccgtt
    26101 ttagcccttt tacccaaaga gcacttttct taatatatct cttctgtgtt tcataatcaa
    26161 caaagaaaag accatatcgc ttattgtagc cattcgccca agaaaattga tcttgcaaag
    26221 accatataaa atagccttga atattgactc ccctatctcg agcctctaaa actttgtgta
    26281 aatgttgctc aatataacgg attcttttac tgtcatcaat aatatcattc tcgccctctg
    26341 gcttaacctc tttaagggct gtaccatttt cagttaaata aatgaccgga tgttgaggat
    26401 attcttcttt gatacgaagc aacatatcaa ataacccttg aggataaata ttccaatccc
    26461 aatctgttgt cggaatacca ggctttttta caaattcacc tagagcattt aatttaaaag
    26521 aagactgtcc ttttattcct gttgaattaa attcttgtct attttcacct ttgtattcac
    26581 gaataaattc tgaacgataa taattcatcc caaacatcgt attaagaggt gcagctcttt
    26641 tcataatttc taaatcacca tcttcaataa taaagctaga attattagct tccaatattt
    26701 gattcaagtg aaaaagcgtg tcatcactgt agtagcccaa aaaagttcca tctaatagaa
    26761 atttattatt ataaacatca taccgtttag ctgccaaaat attttctttt tgcccatcaa
    26821 taggatagcc tggctttaaa gcatgaatac aacctacctt tccctcaatc cctaattgat
    26881 gaaattcgag gactgcaaga gcatgcgcca acaacatgtt atgatttgct tgaattgctt
    26941 cagataattg aaaatggtga ttcggaggaa actgacctcc tatgtattgg cctgcagcaa
    27001 gagacatcag ttcattgatt gtaaaccaat gcttgacttc tgtaaattct tggaaacaaa
    27061 agcgagcata tcgtatgaaa cgatcaatat tctctctatt caaccaatcc cctgtttcta
    27121 acattttctg aggcgaatca aaatgatgta aagaaacaaa cggaatcaca ttatatttta
    27181 agcaggactg aaagactcta tggtaataac gaacagccaa tatattcggc tccccatcta
    27241 tatcaggaaa tatacgaacc caagaaatag ataaacgcaa agcctgcaaa ccatgttctg
    27301 ccgccaaagc tatatcctct tcgtaacgat aataaaaatc actagctgga tctggtaaga
    27361 acggactatt ttcttgcaaa taaacatccc acatatttat tcctttgcca tctaccctag
    27421 ttgcaccctc tacttgataa gcagcggtag cagctcctaa taaaaactcc ttcggtaagg
    27481 ctttaacctg taaattttcc atgactaatc ctcattgcaa accaatatgt tcttcaatct
    27541 ttcgaattcg ttcatattca tcaataaaaa actttacctg atcatacaat agcatcgttg
    27601 tcatcaaagt atcttgacca tgaatcatga taaaactcac ttcaaaatta tctccatatg
    27661 cctcctccgc taataaatta gtctgttctc gatgggcaga cactattgag tcgtttgcag
    27721 actcaaccaa ttctcttgcc tgttcaaaat atccatctct cgcaaacgcc aaagcatcca
    27781 tcaaatctga ccttgcatct cctgcgtaag cgacaattgt aaaaccaagc atatttattt
    27841 cttcttttga tttcatcttt cttcctcctc aatcttgaac catcttttac acatcattat
    27901 taaaatgact tcgctacgat acaaatagaa agtcgaccct aaatatctta aaaatcctta
    27961 aatttcataa tatttaggat caatcttctc tgaatacctt ggttcatttt ctagacttat
    28021 gatttataag tggaaaccag cgtaattttt tgctacttca attacacgat aaacatccaa
    28081 attagattgg aatagcagtt cgtgcccacg gatataattc aacacatttt tccactcatc
    28141 ttgagcttgc cttgtttttc cggttgcttg aagatataaa gccttcgcca tcttgacaac
    28201 atattcacga tgataactga gctgtttcca ttcatccttt tgactattta ataacttaga
    28261 aatattttcc tcaataattg gtaaaaaatt atcagctaga ttgtaagcta tataataatg
    28321 attcgctaaa acatcacttt gacggctgcc aattgcatta aaataatcac aagaggaata
    28381 aatggataat ttttctaaat attcaacaac agactgccaa ttttccccat acaaagcaga
    28441 aaagtattct tcaatcaatt cttcataatt tcttgtcttc ttccagagca tttgccccat
    28501 gacataatta ggaaaattat gagggaatcc ggcacgtaat tcttgacacg aaatgtaccc
    28561 gttcaaatgt aggttggaaa gataagatac atctctgtaa atagtttgac taattttcat
    28621 atagcctaaa tcgccataat gagcacgccc taaaggatag tcatatacga aactatctcc
    28681 tttaaatgct ttttgccact caaaaagata agataaattt tcctcaagag aattcggaag
    28741 tataatttta ttacgcagat aaggtttagg cgtaggtatg gaattgtcaa aatctacatc
    28801 tgcataactc atttcaaatg ttcttgtaat cggtgcaaac atcatggtaa agcgttcagg
    28861 attatctaat ttttctttct gaggtgccca taacaactca tgataaagca gaaaacaaat
    28921 ctttgtatct aatccctcac tcgttaaagc cctatccaat tgattgagaa tacgaatata
    28981 ctgatccgaa accaattctt gtctacagtt ttcgcattca caaatattat tacgagcatc
    29041 cgacaaccat acatgtaagt agttaacatc aggtcttttc ttggcataat ccttgataat
    29101 ttctaccatc ttatcagcta catctggatt tgaaaaatcc aggctggtta aaatcggagc
    29161 cgtattaaac aattctcgtt tcccgtttat ttcagcgaca tagggtttct tctcctctga
    29221 aatactaaga cctgattccc agccaaattt tgaagagtaa cctaaaactt cacctgtcca
    29281 tccatgacca acacgatgat gaataagacc tcttttttgc aattctttat ccaacctatc
    29341 actcaattct tgtactaatt catttgaaaa ttgttcttta tttagatatg gattaaattc
    29401 atgttcatac caacgtttca aaaaagagta gggattttca aactggatga aaaaactgtt
    29461 catcccaatc ttaggtagcc aatcaatgaa atctagtata ttttcaaatg aatccgctcc
    29521 ctctatacat actcccctat gatagtaact ggctgtttca tctatagata gctgtttatc
    29581 taaaaaatct tcaaatcgta actctggaac aaagtcatgt ccgcgccctg gtctagtata
    29641 cacaacccca aattcatgaa acattcggta aattccaata agtaaaccta caattgtatt
    29701 agactcaatt ctccccttac ccttgtctaa tgagataaga acatggtctc ttctatcctc
    29761 tttattgact aatcctacaa aaatatccgc ttccttctcc tcgacaagtt ctatgtcagt
    29821 cttaaagacc cgatttatat agtaacttaa ttcctctaag gcaaagctag aataagtatt
    29881 tttctgctta tcaaatactc tgataaccat cttatttccc tccaacagta gctttttctt
    29941 tttcaagatt gcgtttatct gcaattttga agaatggata ataaattgct acagaaacca
    30001 aaatcaaaac aacttgtaat agagctcctc gccaactagc tcctgtcgca aggaagcctc
    30061 ctatgatcgg tggcattgtc cacggaagga ttacacctgt tgtatagggt actaatccta
    30121 cagccattga tacataggta attaaggcat tgattgtagg agtagcaata aacggaatca
    30181 gcataatcgg atttaaaact gttggaaacg taaatagaat agctgtattg atattaaaaa
    30241 tagacggtat aatagctagc ttacctaatg ttttattcgc acgactctta ctaaatagga
    30301 agagacaaat cgcaagacca atagtcgctc caccgccacc aataaataca aataaatctt
    30361 taaacggtaa tgtaataatg tgttggagtg tttgtcctgc agccacagct tcttggtttt
    30421 ctgtagtaaa ttgtaaccaa actgggtcta caaaagcatt taaaacttgt cccccattaa
    30481 ctccacagaa ccaaaagaat gagtttacaa taacacatag aatcatacct ggaagcgttc
    30541 ctgcaattaa cttaagcggt gttccaacaa ttgcacctag gagtccgttg agacctcctg
    30601 caactcctgc cgcttcaaga ccttttaaga ccagagccca caaaacaaaa gtagtaaagc
    30661 caggtaaaag agctgaaaat gatttactta ccacatctgg gacaccactt ggcattttta
    30721 tcgtaattcc gcgctggata aacatacgat aaatctctgc tgtaaccaat ccaatagtaa
    30781 tcgccataaa caaagaagat gcattcagac tagaaaatgg tattgcgccg ccaaataact
    30841 gcttgacctg ctccccattt ttatcataaa ccatactcga aaaacgaggt gccatcaata
    30901 caaaactgga taaggctatg atccctgccg acggaccatc tgtaccatat ccttccgaca
    30961 acctgtaggc aataccgaaa caagcgacca aggagataat cgctactgtt gactgattca
    31021 tagttgtcaa gatacttagc aatccaacac tattcagcca atttgtaaaa gcctcttgag
    31081 gccaactgat tagaataaga aataaagagc cgactaaaat caaaggcatt gccatcataa
    31141 atccttcacg aatagctttc aaatgccgtt ggttgccaac tttttcacca aacggagcga
    31201 cttttgtttc taaaaacgct aaaatattgt tcatcaccgg aactcctttt tttatttttt
    31261 ataaattaaa tata
//
LOCUS       DAVIME010000025        28083 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVIME010000025 DAVIME010000000
VERSION     DAVIME010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.025"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(100..3276)
                     /gene="carB"
                     /locus_tag="VV588_001193"
     CDS             complement(100..3276)
                     /gene="carB"
                     /locus_tag="VV588_001193"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU7083544.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(3589..4668)
                     /gene="carA"
                     /locus_tag="VV588_001194"
     CDS             complement(3589..4668)
                     /gene="carA"
                     /locus_tag="VV588_001194"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU7083545.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            complement(4718..5641)
                     /locus_tag="VV588_001195"
     CDS             complement(4718..5641)
                     /locus_tag="VV588_001195"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU7083546.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            complement(5660..6181)
                     /gene="pyrR"
                     /locus_tag="VV588_001196"
     CDS             complement(5660..6181)
                     /gene="pyrR"
                     /locus_tag="VV588_001196"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU7083547.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            complement(6392..7021)
                     /gene="nth"
                     /locus_tag="VV588_001197"
     CDS             complement(6392..7021)
                     /gene="nth"
                     /locus_tag="VV588_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU7083548.1"
                     /translation="MVLSKKRARKVLEEIITLFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            complement(7021..7563)
                     /locus_tag="VV588_001198"
     CDS             complement(7021..7563)
                     /locus_tag="VV588_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU7083549.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            7733..8050
                     /locus_tag="VV588_001199"
     CDS             7733..8050
                     /locus_tag="VV588_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU7083550.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FEF"
     gene            8289..9848
                     /locus_tag="VV588_001200"
     CDS             8289..9848
                     /locus_tag="VV588_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU7083551.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLTMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLSKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(9892..10791)
                     /gene="htpX"
                     /locus_tag="VV588_001201"
     CDS             complement(9892..10791)
                     /gene="htpX"
                     /locus_tag="VV588_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU7083552.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10793..11353)
                     /locus_tag="VV588_001202"
     CDS             complement(10793..11353)
                     /locus_tag="VV588_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU7083553.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            11447..12160
                     /gene="rsmG"
                     /locus_tag="VV588_001203"
     CDS             11447..12160
                     /gene="rsmG"
                     /locus_tag="VV588_001203"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU7083554.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            12414..13697
                     /locus_tag="VV588_001204"
     CDS             12414..13697
                     /locus_tag="VV588_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU7083555.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(13892..15463)
                     /gene="ffh"
                     /locus_tag="VV588_001205"
     CDS             complement(13892..15463)
                     /gene="ffh"
                     /locus_tag="VV588_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU7083556.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15475..15807)
                     /locus_tag="VV588_001206"
     CDS             complement(15475..15807)
                     /locus_tag="VV588_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU7083557.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            complement(15898..16275)
                     /locus_tag="VV588_001207"
     CDS             complement(15898..16275)
                     /locus_tag="VV588_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU7083558.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            16347..17651
                     /locus_tag="VV588_001208"
     CDS             16347..17651
                     /locus_tag="VV588_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU7083559.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            17664..18470
                     /gene="yidA"
                     /locus_tag="VV588_001209"
     CDS             17664..18470
                     /gene="yidA"
                     /locus_tag="VV588_001209"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU7083560.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTLVL"
     gene            complement(18525..18596)
                     /locus_tag="VV588_001210"
     tRNA            complement(18525..18596)
                     /locus_tag="VV588_001210"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18561..18563),aa:Arg,seq:cct)
     gene            complement(18638..18985)
                     /gene="rplS"
                     /locus_tag="VV588_001211"
     CDS             complement(18638..18985)
                     /gene="rplS"
                     /locus_tag="VV588_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU7083561.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(19104..19433)
                     /gene="crcB"
                     /locus_tag="VV588_001212"
     CDS             complement(19104..19433)
                     /gene="crcB"
                     /locus_tag="VV588_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU7083562.1"
                     /translation="MVIVYLAIACGFGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(19427..19801)
                     /gene="crcB"
                     /locus_tag="VV588_001213"
     CDS             complement(19427..19801)
                     /gene="crcB"
                     /locus_tag="VV588_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU7083563.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(19798..20064)
                     /locus_tag="VV588_001214"
     CDS             complement(19798..20064)
                     /locus_tag="VV588_001214"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU7083564.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(20180..20623)
                     /locus_tag="VV588_001215"
     CDS             complement(20180..20623)
                     /locus_tag="VV588_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU7083565.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            20727..21662
                     /locus_tag="VV588_001216"
     CDS             20727..21662
                     /locus_tag="VV588_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU7083566.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            21716..22000
                     /locus_tag="VV588_001217"
     CDS             21716..22000
                     /locus_tag="VV588_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU7083567.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(22057..22635)
                     /locus_tag="VV588_001218"
     CDS             complement(22057..22635)
                     /locus_tag="VV588_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEU7083568.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(22610..23623)
                     /locus_tag="VV588_001219"
                     /pseudo
     CDS             complement(22610..23623)
                     /locus_tag="VV588_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(23626..24082)
                     /locus_tag="VV588_001220"
                     /pseudo
     CDS             complement(23626..24082)
                     /locus_tag="VV588_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            24619..25965
                     /gene="gdhA"
                     /locus_tag="VV588_001221"
     CDS             24619..25965
                     /gene="gdhA"
                     /locus_tag="VV588_001221"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU7083569.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGHLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(26471..26641)
                     /locus_tag="VV588_001222"
     CDS             complement(26471..26641)
                     /locus_tag="VV588_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083570.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(26654..27232)
                     /locus_tag="VV588_001223"
                     /pseudo
     CDS             complement(26654..27232)
                     /locus_tag="VV588_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(27249..28054)
                     /locus_tag="VV588_001224"
                     /pseudo
     CDS             complement(27249..28054)
                     /locus_tag="VV588_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT         8288 a         6178 c         5273 g         8344 t
ORIGIN      
        1 gcgaacgaat caattagaaa attcaaatta atttctagaa atattttagt atccctgtgt
       61 actgttctaa attcagtctg ctatatctta tttttctatt taaatcgctt ctgtaacaaa
      121 gctacgactt tcaagtacct taagcatggc attagctgta tctagcgctg tgaagagggg
      181 caccccgtgt tcaatggctg aacgacgaat ttgctcacca tcttcgtcag cagttcgttt
      241 tgttcctact gtgttaatga tagcttgaat tcttcctttg cgtacaaaac ttgggatatc
      301 cttatcgtca tcaccaatct taccaacagg ttgggcttgc aagccatggc tagcaaagaa
      361 ggctgctgtc ccttctgtcg caaggattcc ataaccaatg ttttggaaac gacgagccaa
      421 gttcaaggct tcttctttgg catcatcagc gatggtaaag acgacattac caaaagttgg
      481 caagtgtaga taagaagctt caaaggcttt atagagagct ttttccaaag tagcatcaga
      541 acccataact tcacctgttg acttcatttc aggaccgagc aagctgtcta ccttagctag
      601 tttggtaaag gagaagacag gtgccttgat atgaacacgg gtgctttcag ggtaaagtcc
      661 attttggtag ccaagttctg ataaactttg accaagaatg agcttggtcg ctacttgagc
      721 cataggaata ttggttacct tagataggaa tggaacagta cggctggcac gtggattgac
      781 ctcaataacg tagacttttt catccttgat aacaaactgg atgttcatca ttccaaggca
      841 gtgaagaccg attgctaagc gtttggtgta gtctgcgatg gtctcctgaa ccttttgcga
      901 caaggtttgt ggtgggtaaa cagccattga gtcacctgag tggacaccag cacgttcgat
      961 atgctccatg ataccaggaa tgagtacatc tttaccatct gaaatggcat caacttcgca
     1021 ctcttgccca acgatataag agtcgacaag aactgggtga tctggactag ccttaacagc
     1081 agttcgcatg taagaacgaa ggtcttcttc gttttcaacg atttccatgg cacgtccacc
     1141 aagtacataa gatgggcgga caagaactgg gaagccaatc ttacgagctg caagagctgc
     1201 ttcttcttca ttggtagccg tttgtcctgg tggctgtgga atatccaatt ctttgagagc
     1261 ttgctcgaag aggtcacggt cttcggcacg gtctaggtca gcaacctgtg taccaaggat
     1321 ggtcacacct gcttttgcca atggctccgc aaggttgatg gctgtttgac caccgaactg
     1381 aacgataact ccctttggtt gttccaagtc aatgacgttc ataacatctt cgaatgtcaa
     1441 tggctcaaag taaagcttat ctgatacaga gaagtctgtt gaaacggtct ctgggtttga
     1501 gttcatgatg atagcttcat aaccagctgc ctggatagcc ttaacagagt gaacggttgc
     1561 gtagtcaaac tcaacccctt gaccgatacg gattggacct gaacctagga caagtacaga
     1621 ttctttatca gatctgatag attcattttc ccaaccatag gttgaataga aatatggcgt
     1681 ttcggagtcg aactctgccg cacaagtgtc taccatctta taaactggaa caatcttgtt
     1741 ttccaagcga agttggcgaa ctttatcatc agtcgttccc cagagttcag caatcttacg
     1801 gtctgaaaaa ccattaagtt tggctgtttt caaaacttct agatcttgtg gatgagcacc
     1861 caattcttgc tcaatttcaa agatatgcaa gagtttatca agatagaaga tatcaatttt
     1921 tgtaagctct gcaatttctt caggtgtgta gccacgacga attgcttctg atacgtagaa
     1981 gagacggtca tcttgggctt tgacaacctt ttcaatcaag gcatcatcag aaactgctgc
     2041 aagttcaggt atttcattgt ggtgcacccc aatttcaagg gagcggcagg ccttgagaag
     2101 agattcctcg atgttacgac cgattgccat gacttctcca gtcgccttca tttgtgtacc
     2161 gagacggcgt tcaccctttt caaacttgtc aaatgggaaa cgtggaatct tagcaactac
     2221 gtagtcaagg gctggttcaa acatggcata ggttgaacct gtaactgggt ttataacctc
     2281 atccaaggtc aaacctactg caatcttggc agccaactta gcaatcggat atcctgtcgc
     2341 tttagaagca agggctgacg aacgtgatac acgagggttt acttcgataa cataatactt
     2401 gaagctgtta ggatcaagag ctagctgaac attacatcca ccttcaatct tgagggcacg
     2461 aataatgctc aagctcgcat cacgaagcat ttggttttca tagtctgaca tggtttgcgc
     2521 aggggcaaat acaatggaat cccctgtgtg aatcccaact gggtcaaagt tttccatgtt
     2581 acaaacaacc aaggcattgt cagctgagtc acgcatcact tcgtattcaa tttccttgaa
     2641 accggcaatc gaacgctcaa tcaaacattg ggtaacaggt gacaatttca aaccattttc
     2701 agtgatttca cgcaattctt tctcgttggc acacatacca ccaccagtac caccaagggt
     2761 aaaggctgga cgaacgatga ctgggtagcc aattgtcgct gcaaaggcaa ctgcttcttc
     2821 tactgtgtta acaatttcag attctggaat gggttgttca agctcttcca tcaattgttt
     2881 aaagaggtca cggtcctccg cttggtcaat ggcagataat ttggtaccca gaagttcaac
     2941 gccaagctcg tctaggatac catttttaga taattccatg gccatgttga gacctgtctg
     3001 accaccgagt gttggtagca aggcatctgg acgttcctta cgaagaatac gtgtcacaaa
     3061 ctcaagtgta atcggttcaa tgtaaacctt gtcagcaatt tccttgtccg tcatgatggt
     3121 tgcaggattt gagttaacca aaacaacctc ataaccttcc tctttcaacg acaagcaagc
     3181 ctgagtccca gcgtagtcaa actcagcagc ctggccaata ataatcggac cagaaccaat
     3241 caccataatt ttttgaatat cagtacgttt aggcatatat aagatattaa gggcgtcaag
     3301 cggacaaagc taaaatagga gttatgacga agaactgtca gttctaggaa taactatctt
     3361 tttagcaccg tccgtagccc gtattcagtt cagcaaatac ggagcaccct tctcctttct
     3421 attcgtcgcc tctcagggcg acattaaata agatacaaag gacgaataga aagcgattga
     3481 attttagaaa atcaaggaag gattgacaat ccaagttgat ttctctacat tctgagcttt
     3541 ccgtccgtgt tcagttacat aaattctccg acgagctttt actcgttctt agtttgattg
     3601 tttaaaaact tccatcatct cgataaactc gtcaaatagg tagctagcgt cgtgtggccc
     3661 aggagctgca tctgggtggt attgaacaga gaaagcaggt tggtatctgt ggcgcacacc
     3721 ttccactgac ttgtcattga tttcttcgtg ggtaataatc aagtgctctg gcaaatcctc
     3781 gcggctgact gcataaccat ggttctggct ggtgaagtct actcgtcctg ttgcgatttc
     3841 acgtaccgca tggttgaatc cacggtggcc aaacttcatc ttataggtct tagccccgtt
     3901 tgccattgca aagagttggt gtcccataca aataccaaag attggaattt ttccttgtac
     3961 accgcgaatc atgtcgagtg cttgtggaac gtcttctggg ttacctggac catttgacaa
     4021 cataacccca tcaggattga gatggagaat ttcttcagcc gttgtcgaat aaggaacaac
     4081 tgtcacgtta cagttgcgtt tagaaagttc acgtaggatt gagtgcttga gaccaaagtc
     4141 cactagcacc acgctcaaac caactcctgg agctggataa gacgttttag tagaaacctg
     4201 tttgatattg tctgtcggta aaactgttgc ttggagctgg tccgtcacat ggtccatact
     4261 gtccccaaca tgggtcaagg ttgcacgcat agtaccatgc ttacggataa tcttggtaag
     4321 agcacgcgta tcaattcctg aaatccctgg aatttttttg gctttcaaaa attcatccaa
     4381 ggtcatttgg ttgcgccagt tgctagctct acgcgcttct tcaaaaacaa cgactccctt
     4441 acaagttgga ataatggatt cataatcatc acgattaata ccataatttc ctaccaaagg
     4501 ataagtaaag gtcaagattt gtccattata agactggtct gtaatggatt cttggtagcc
     4561 ggtcatccct gtattaaaga cgatttcgcc tgttacatca atatctgctc cgaaggcctt
     4621 gccttcaaaa actgtgccat cttctaatac tagaattctt tttgtcatat tttcacctct
     4681 cgtggacgct cactggcgtc ttttaacgtc ttgtgtttta gttggcgttt ctactcgcta
     4741 gtacggattc taagattgcc attcgaacaa agacaccatt ggtcatttgt tggacaatcc
     4801 gtgattttgg tgcttcaacc aagtggtctg ctatttctac atcacgattg attggagctg
     4861 ggtgcatgag gattgctgtt tctttcaaac gatcgtaacg ttcttgagtc aagccatgtt
     4921 gggcatggta gtcttctttt gaaaatacag ctccactatc atggcgttcg tgttgcacac
     4981 ggagaaacat catgacatca acctgatcaa tgatttcatc aatggttaca aactgtccat
     5041 agtctgcaaa ctcttgactt ctccattcct caggtccagc gaaaaagagt tcagctccca
     5101 agcgtttcaa aatctgcata ttggatttgg caacgcgtga gtgatccaag tcacctgcaa
     5161 tagcaacttt aagaccctca aagtggccaa attcctcata aatggtcatc aaatcaagca
     5221 agctctggct agggtgttgg cccgaaccat ctccaccatt gatgatggaa gtcgtaatcg
     5281 ttggactagc aatcaattct ctatagtagt cgacctctgg atggcgaatc acacagacat
     5341 ccactcctaa agcagacaga gtcaaaatgg tgtcataaag tgtctcaccc ttattaaccg
     5401 aactagtctt cacatcaaag tcaagtcgtt ccaatccaag tttaatctct gcgacttcaa
     5461 aggacttatg tgtccgtgta gaatcctcaa agaagagatt ggaaacaatc ggatggtctt
     5521 catagggaag ctgggctcca tttttaaact caattcctcg cttgatcaat ttcattactt
     5581 gatcgacagt gaggtcttcc atggacacca catggttcaa tgcttgttga ttttctgaca
     5641 tggctactcc tttaactttc taagcttctt cagtaatcag aactctgtct tggtcatcaa
     5701 gttctgtcat ctctacgatg atttcttcag aacgactggt tgggatattt tttccaacgt
     5761 aatctggacg gattggcaat tctctatgtc cacgatcgac tagaactgct aaactcacac
     5821 gcgcaggacg accatgaccg acaatattat caatagcagc acggatggta cgacctgtat
     5881 agagcacatc atccaccaag ataacttcgc ggtctgtcac atcgacagaa accaaagaag
     5941 tatcttctcc acttttaaca tcatcacgga aaggtttagt atccaattcc acaacaggaa
     6001 ctgaaagatt ttctaactgc ttcaaacgtt cttggattcg gtgggcaata aagacaccac
     6061 gagttttaat accagccaag acgatcttat tcaaatcttt gttgcgttcg ataatctcat
     6121 aagtaatacg cgtaatcgct cgtttgacgg tcaattcgtc tacaacttct tttgttttca
     6181 tgacaaacct ccaaaaagaa aagtctcctt aaacaaggag acttgaaatt tatagccaag
     6241 cgagccctac tgcacacagt atagacttca cccttctact ttatcgcgct ccttgcctgc
     6301 ctcacgggac aggtttaaag gaatatttag ttatcattta ctatagcaca aagcatgctt
     6361 aaaatcaagc aaaaagtttc aatgtagcat cttacaaatt gctaaaatca tataattgtg
     6421 ggtactggtc acactctgga ttttttggat ggcaaatggc tcttccaaaa taaatcatgg
     6481 cctgatgggc agctaaccac tgctcaggcg gcaagatatc catgacccgc ttttccacct
     6541 caagtggcgt cgctgatttt ttgacaatat cgtggtgttt gcaaatacgc tccacatgag
     6601 tatccactgc aaaggctgga atcccaaatc ctacactcat gacaacattg gctgtcttgc
     6661 gaccaacacc tgccaaactc tccaattctt cacgtgtctg agggacttga ccatcaaaat
     6721 cgtctagtaa ctgttgggca cattttttaa ggaatttagc tttattccga tacaatccca
     6781 agcgagaaat atgtgaagca atctcactct ctgtcgctac agacatagct tggggtgttg
     6841 gaaaggcaac aaagagacct ggtgtggcct tatttaccgc tgcatctgtc gtctgggctg
     6901 ataacatgac cgcaaccagg agttcaaaat gattggtaaa atcaagacta ggcttggcat
     6961 ctgggaagag ggtaatgatt tcttctagca cctttcgtgc tcgttttttt gacaagacca
     7021 ttattcatct ccgtcaaata gtccttgtaa gccagcaaaa ggactgtttt cttctttctt
     7081 tactgctttt tgagcttggt attcttcctc tgtcatgatt tgccagtcat ttcctgagat
     7141 aaatccttga ccagcttctt cttcagccgt caagaccttg ataggaatgt ttagcaggat
     7201 attgtctgat acactctcag caaggtcaag ctccccattt tcgatgggca agaccaagtc
     7261 atcatctaaa acttcttgat ctagctggtt agttgcgcct tccatgaaaa cttccgtgac
     7321 tggataagat tcaactaact caactggctc catactgcga ctcgaagcaa gaacaatggt
     7381 ataagatagt tgataatcta agaaatacat acggtcttca tattgtactt tcccaactgc
     7441 aaggatatct tttacatcta aaatttcttg attacgtgca cgcaggtcat caactaaatc
     7501 taacgtttgt tcaaagttca aaccttcaga ctgcttacga atttcttgaa tatttaattt
     7561 catacttcct ccataaagat ttactctctt gattatacca tgaaaaggct acaaatcagc
     7621 acaccaaact ttgtaattaa aattcaaaat tttaacatat ttactattat agttttattt
     7681 tttagtgcta tactataggg aaagagtaca tcagatcaag gaggatgctc acatggaaga
     7741 caagaaactc attcaactcc tatccaagtt aaataaaagc taccaaaact gtaaacaggg
     7801 tacggcagat gatattcgac tacaagagct gctaaacact actatgcaag agctcaaaaa
     7861 aacggaacag ttgaacaaca gtatcttaat tgatcttgag aaattttacc aacctaccag
     7921 tcttctgatt ggactgggta gcctaaaact aaacgatcaa gcacgcactg cttggcgaaa
     7981 ctatgataaa ttccattacg agcatgtcaa acacgtacta agtctctatg gacctgtttt
     8041 tgaattttag agcatagaat ttccagtttt ctgttgacaa aatttcctta aaggtataat
     8101 ataaagatac taatactcgg aggtaaggga gacatgaaca actaagtcta tcaaataaag
     8161 aacctttatt tagtagatct tgtttttgtc tctttttgtg tgctctttta tgctcttttt
     8221 ctggcatgtt aatagagttt ttttgacata gactttgggc tctactaggt aaagtagagc
     8281 tttttgttat gcactatgaa cattctagaa agggaaatca tatgataaaa atcaatcatc
     8341 taaccatcac acaaaacaaa gatttacgag atcttgtatc tgacctaacc atgaccatcc
     8401 aagacgggga aaaggttgct attattggtg aagaaggaaa tggcaaatca accttactta
     8461 aaattttaat gggggaagct ttgtctgatt tcactatcaa gggaaacatc caatctgact
     8521 atcagtcact ggcctacatt cctcaaaaac ttcccgagga gctgaaaaag aaaactttac
     8581 acgactactt ctttttagat tctattgatt tagactacag tatcctctat cgtttggcgg
     8641 aggaattgca ttttgatagc aatcgtttcg caagtgacca agagattggc aatctatcag
     8701 ggggagaagc tttgaaaatt cagcttatcc atgagttagc caaacccttt gagattctat
     8761 ttttagatga accttcaaat gacctagacc ttgagacagt tgattggcta aaaggccaga
     8821 ttcaaaagac caggcaaacc gttattttca tttcccatga tgaagacttt ctttctgaaa
     8881 cggcagacac tattgttcac ttgcgactgg tcaaacaccg taaagaagcg gaaacgctag
     8941 tagagcattt agactatgat agctatagtg agcagagaaa ggctaatttt gccaaacaaa
     9001 gtcagcaagc tgctaacaac caaagagcct acgataaaac catggaaaaa catcggagag
     9061 ttaagcaaaa tgtagaaact gcgcttcgag ctaccaaaga tagtactgcc ggtcgcctat
     9121 tgtctaaaaa gatgaaaact gtcctctcac aagaaaaacg ctacgaaaag gcagctcagt
     9181 ccatgactca aaaaccactt gaagaggaac aaatccaact tttcttttca gacatccaac
     9241 cattaccagc ttctaaagtc ttagtccaac tggaaaaaga aaatttgtcc attgacgacc
     9301 gagttttggt tcaaaaacta caactaactg tccgtgggca agaaaaaatc ggtattatcg
     9361 ggccaaatgg tgttgggaaa tcaactctgt tagccaaatt aaagcaactt ctgaatgata
     9421 aaagagagat ttcccttggt tttatgccac aagattacca caaaaaacta caattggatt
     9481 tatcaccaat agcttatatc agcaaaactg gggaaaaaga ggaacttcag aaaatccact
     9541 ctcacctagc cagtctcaat ttcagttatc cagaaatgca gcatcaaatt cgctccttat
     9601 ctggcggaca acagggaaaa ctcctgcttt tggatctagt cctgcgcaaa ccaaactttc
     9661 tcctgctgga tgaacccaca cgaaactttt ctcccacttc tcaaccccaa atcagaaaac
     9721 tctttgcaac ctatccaggc ggtctcatca ctgtttcgca tgaccgtcgt ttcttaaaag
     9781 aagtctgctc gatcatctat cgcatgacag aacacggttt gaagctagtt aatttagaag
     9841 atttataaat ttgcaacata gcaaaaatcc agagacgacc tctggattct tttacatctg
     9901 ttttaaacgt tcaatccgtt ctgagatagg tgggtgggta taaaagagtt tttggaaccc
     9961 cccacctttc ttgggatcat tgatataaag agcactgcta gcatcatcga cgtggcgact
    10021 catcggtttg ctattgtcca acttatctag ggcattaatc attccctggg gattgcgagt
    10081 cagctcaaca ctagatgcat ctgccagaaa ttccctctga cgagaaatag cgagctgaac
    10141 caaggttgca gcgagaggtg ccagtacaat agctagtagg gaaaccacta gcataatgat
    10201 ttcaagacca tttccatctc ggtcatcatc acttcgtctg cgacctgctc caccccacca
    10261 catcatacga cctgccatac cagaaagcat ggtgatagca ctagcaaggg caactgcaat
    10321 agtcgaaata cggatatcat aattacgaat atgactgact tcatgtccca taacagcttc
    10381 tagttcttca cgattcatga tagctagtag acctgaagtc gcagcaacag ccgcattttg
    10441 aggattagaa cctgtcgcaa aggcatttaa ggctggatca tcaatgatga aaacacgggg
    10501 cataggaatc tgagcgacca gagccatatc ttccactaca tggtagaggt ctggtgccgt
    10561 ttgctcatcc acctcacgcg ctccattcat ggacatgaca atctctgtcg attgaaaaat
    10621 catagacaaa gcgtagataa agccgataat cagtgcgata accaaaccac caagtccaga
    10681 tcttataaag agataaccaa ccgcataacc aacaagagct aagagtagga aaaataccag
    10741 caacaaaatc caggtttttc gtttattgct tgcaatttga tcaaacaaca tcttagtcac
    10801 ctaaaccgct aaaatcaact ttaggaaccg acttttcctc ttcaggtgtt tgaaggaaat
    10861 ctgccgcttt aaatccaaac attccagcga taatattgct cgggaaagtt tctaatttta
    10921 cattgtagtt gctgacaaca ctgttataga gttgacgaga gtaagaaatt ttattttctg
    10981 tgtttgtcaa ctcctcttgc aatttaacaa agttagcact agctttcaaa tctggatagc
    11041 tttctgcaac tgcaaaaata cctgaaacct gacgagtgag ggcatcactg gctttcatag
    11101 cttctgctgg tgaagtcgct gccgccactt ggttacgtag ttctgccacc ttttcaaggg
    11161 tagaaccttc atatttggca taacctttta cagtctcaat caagttcggc aagaggtcat
    11221 ttcgacgttt caactgaaca tcaatctgac tccaagcctc cttggtttgc atacgatttt
    11281 taaccaaacc gttatagcta acaatcacaa aaataacaat aagagcgata actccaagaa
    11341 taatccaagt cataatataa gtcctttctg cttttagatt agtaccagta tatcaaattt
    11401 tctatgattg tggtaaaata agatgatact aaagaaggaa ataactatga aaccaaaaac
    11461 attttacaac ttgcttgccg agcagaatct tccactttcg gaccagcaaa aagaacaatt
    11521 tgaacgttat tttgagctct tggtcgagtg gaatgagaag attaatttga cggcgattac
    11581 ggacaaggaa gaagtttatc tcaaacattt ttacgattcg attgcaccca ttcttcaagg
    11641 tttgattccc aatgaaacta tcaaacttct tgatatcggg gctggggcag gatttcctag
    11701 tctaccaatg aaaattctct atccggagtt agatgtgacc attattgatt cactcaataa
    11761 gcgcatcaac ttcctacaac tcttggctca agaactggat ttgaacggag ttcatttcta
    11821 ccacggacgt gccgaagatt ttgcccaaga caagaacttc cgtgctcaat atgattttgt
    11881 aacagctcgt gcggttgccc gtatgcaggt cctatctgaa ttgaccattc cctaccttaa
    11941 ggttggtgga aaactattgg cactcaaggc cagcaatgcg cctgaggaat tattagaagc
    12001 taagaatgcc ctcaatctcc tttttagtaa ggtcgaagac aatctcagct acgccctacc
    12061 gaatagagat ccgcgctata tcacagtggt agaaaagaaa aaagaaacac caaataaata
    12121 tccacgtaag gctggtatgc caaataaacg cccactttaa attttttagt aaacaaatgt
    12181 ttacaaaatc agcctcgctc ttttatttct aggctcggga aaaaatgatt tacaaaatca
    12241 tttttttctg ctatactatc ctaagcaaag gtttttaatg tcatcccgtg aggtgacgaa
    12301 gacgcagaaa tatttaaaac tctttaaaat ctaaatttta aagaagtctt actctgaggg
    12361 cctattgctg taaaataatg ggctcttttt tgatgcccaa aagtgaggtt tatatgaaac
    12421 aagaatcaac tgttgatttg ttactagacg ttgaccaacg tccttcggct ggaaaaggaa
    12481 ttctccttag tttccaacac gttttcgcca tgtttggtgc gaccatcttg gtaccattga
    12541 ttttgggaat gcctgtatct gttgcccttt ttgcttcagg tgttggaaca ctcatctaca
    12601 tgcttgctac tggttttaaa gttccagttt atctaggttc ttcattcgcc tttatcacag
    12661 ctatgtcact ggctatgaaa gaaatggggg gggatgtatc tgctgctcaa acaggggtta
    12721 tcttgactgg tttggtctat gtccttgttg ctaccagcat ccgatttgta ggaacaaaat
    12781 ggattgataa actcttgcca ccaatcatta tcggtcctat gatcatcgtt atcggtcttg
    12841 gacttgcagg ttcagctgtt accaatgcag gtcttgtagc agacggaaat tggaaaaatg
    12901 ctctggtagc cgttgttact ttcctaattg ctgcctttat caatacaaaa ggaaaaggct
    12961 tcctacgaat cattccattc ctctttgcca ttatcggtgg ttacctcttc gcactaactc
    13021 ttggtttggt tgactttacg cctgtcctag aagctaactg gtttgaaatt cctggtttct
    13081 acttgccatt tagcacaggt ggtgccttta aagagtacaa tctttacttt ggtccagaag
    13141 ccatcgctat cttgccaatc gctatcgtaa caatttctga acatatcgga gaccatactg
    13201 ttttgggtca aatctgtggt cgtcaattct taaaagaacc aggtcttcac cgtactcttc
    13261 ttggtgacgg tatcgcaact tctgtttctg ccttccttgg tggaccagcc aatacaactt
    13321 acggagaaaa tacaggggtt atcggtatga ctcgtatcgc ttctgtctca gttatccgta
    13381 acgctgcctt catcgcgatt gccctcagct tccttggtaa attcactgcc ttgatttcaa
    13441 ctattccaaa cgctgtactt ggtggtatgt caatccttct ctatggggtt atcgccagca
    13501 atggtttgaa agtcttgatt aaagaacgtg ttgatttcgc tcaaatgcga aacctcatca
    13561 tcgcaagtgc tatgttggtt cttggacttg gaggagctat ccttaaactt ggtccagtta
    13621 cactttcagg tactgccctt tcagccatga caggaatcat cttgaacttg atcttgccat
    13681 acgaaaataa agactaagag tctaaataca cctaatccac tcagacagct gagtggattt
    13741 ttcgtatacc ataataaaag tgtcttaaca aaattattaa aatcaaaaaa cgtataatat
    13801 cagatattct aaaaccttga tactgtacgt tttatcatag aaatttttac tttattttct
    13861 catcaaatga gatttgcatc aatctcttgt cttacttgcg tttcttcttc gctttcttca
    13921 ttttgttagc catacgtttc atggactgtt tcatggcaaa ttcaccaatt ttacctttca
    13981 aaccgccacc aaacatctgg ctcatatctg gcattcctgc tcctccgaga gctgataagt
    14041 caggcatacc gccttgtccc atcattcctt caagggcaga catatccatt cctcccatat
    14101 ttggcatatt tttaggaagg ttatttggat taatccccat ttgcttcatc attttattca
    14161 tatccccaga cataacaccc tgcatgagct gtttagcctg gttaaagtcc ttgatgaatt
    14221 tattgacttc gacgaatgta tttccagaac cagcagcaat acgacggcga cggcttggat
    14281 ttaacaaatc tgggttttca cgctcttcag gtgtcatcga agacacaatg gcacgtttac
    14341 gagcaatctg gcgttcatcc accttcatgt tttgaagggc tggattgttg gccatacctg
    14401 gaatcatctt gagcaagtct tccatcggcc ccatattttg cacctgatct aattgatcga
    14461 tgaaatcatt aaaatcaaag gtgttttcgc gcatcttctc agccatttca agggcttttt
    14521 gttcatcgta ttcctgagaa gctttctcaa tcaaagtgag catatccccc atgccaagga
    14581 tacggctaga catacggtct gggtggaagg tttcgatatc tgtaattttt tcacctgtac
    14641 cagtgaactt gattggtttt ccagtgatgt gacgaacaga cagagcagca ccaccacgag
    14701 tatcaccatc aatcttggta aggatgaccc cagtcacttc caactgagca ttaaactcac
    14761 gcgcaacatt ggctgcttcc tgaccaatca tagcatcaac gacaagcaag atttcatttg
    14821 gttgagccaa tactttcaca tcacgaagct cattcatgag gagctcatca atctgcaaac
    14881 gacccgcagt atcaatcaag acatagtcgt tatgattagt ttgggcttgc tccaaacctt
    14941 gacgtacaat ctcaacagct ggtacttctg ttccaagtgc aaagacaggc acatcaatct
    15001 gttgtcccaa ggtcttaagc tggtcaatgg cagctggacg ataaatatcc gccgcaatca
    15061 tcaaaggacg agcattttct tctttcttga gtttgttggc caatttacca gcaaaggttg
    15121 ttttaccagc cccttgtaaa ccaaccatca tgatgatggt tggaatctta ggtgacttga
    15181 taatttctgc cgtatcagaa cctaaaacgg ctgtcagttc ctcatcaacg attttaataa
    15241 tctgttgcgc aggattaagc gtatcaatga cctcatgccc gactgcacgc tcacgaactt
    15301 tcttgataaa gtcctttaca acaggcaagg caacgtcggc ctcgagcaag gccaagcgaa
    15361 tttctttggt tgcctcttgg acatcagatt cagagatttt tcctttttta cgtagatttt
    15421 taaagacgtt ctgcaaacgt tctgttaaac tttcaaatgc catttttctt cctcttattc
    15481 tctattatca atgcttgtta aaatttctat ctgctcctgc agaaagtcat ccttgggata
    15541 gcgctccaaa atctgatcaa aaatctgact gcggacaata tagtccgagt acatgtgcaa
    15601 tttcatctca taatcttcca gaatcttttc tgttcgcttg atattgtcat agacagcctg
    15661 acgactgaca ccgaactcct cggcaatttc agcaaggctg taatcatcag cgtagtagag
    15721 ctcgatataa ttcatttgct tatctgtcaa aagcgccgca taaaattcaa agagcgcatt
    15781 catacgattg gttttttcga tttccataac ttttattata ccaaaaatta gcctaatcta
    15841 ccacactagg aagccgatcc aagaagatag atagctaaat ttgaaaaaga catgagccta
    15901 gccccaagta atttccaatt gatagctggc aaagggatgt ccctcttgat tttgtagttg
    15961 ataatctagt tcaatctttt gcccatccac ttgataacga ttcgtttgga taataaactc
    16021 ctgcataccc ataggtgtgg gaatataggc taaactatca ctatccttta gaaagcgcat
    16081 aatggtcttg ggattggaaa atcgactcat cacaagttct tgaccatgaa atttaatcac
    16141 tactttttcc ttttcctcat tatagaaaag caggtagcta taatctcctt tttcatgcac
    16201 ttccacatca taaagctggt caatcacttc caactgctca tcaaactgaa ttgtatttcg
    16261 catccgaatc ttcacatcag gccctctttc ttgtctcttg tcctactatt ttaccaaaaa
    16321 gagcaggatt ttgctataat ggtcatatga acgaaaaagt attccgtgac cctgttcaca
    16381 actacatcca tgtcaataat caaatcatct atgacttgat taatacaaaa gaatttcaac
    16441 gtttgcgccg gatcaaacaa ctgggaactt ccagttatac cttccacggt ggagagcata
    16501 gtcgcttctc tcactgtcta ggagtctatg aaattgcacg acgcatcaca gagattttcg
    16561 aagaaaaata tcctgaggaa tggaatcctg ccgagtctct cttgaccatg accgctgctc
    16621 tcctacacga ccttgggcat ggtgcctact cccatacttt tgaaaatctc tttgatacag
    16681 accatgaagc cattactcag gagattattc aaaatcctga gacagagatt caccaagtcc
    16741 tgctacaagt ggcacctgat ttcccagaaa aggtggccag tgtcattgac catacctatc
    16801 ctaataagca ggtcgtgcag ctcatttcta gccagattga tgcggaccgc atggactatc
    16861 tcttgcgtga ctcctatttt acaggagcat cctatgggga atttgacctg actcgaatcc
    16921 tccgagtcat tcgtcctatc gaaaatggta tcgcctttca gcgcaatggc atgcacgcca
    16981 tcgaagacta cgtcctcagt cgctaccaga tgtacatgca ggtttatttc caccccgcaa
    17041 cacgcgccat ggaagttctc ctacagaatc ttctcaaacg cgccaaggaa ctctatcctg
    17101 aggacaagga tttctttgcc cgaacttctc cacacctcct gcctttcttc gaaaaaaatg
    17161 tgaccttgac tgactatctg gctctggatg atggcgtgat gaatacctac ttccagcttt
    17221 ggatgaccag tcctgacaag attcttgcag atttatcgca tcgctttgtc aaccgcaagg
    17281 tctttaaatc cattaccttt tcacaagagg accaagatca acttactagc atgagaaaat
    17341 tggttgagga tatcggcttt gatcccgact actacactgc cattcataag aactttgacc
    17401 tcccttatga tatctatcgt cccgaatctg aaaacccacg gacacagatt gagattttac
    17461 aaaaaaatgg agaactggcc gaactctcta gcctgtctcc tatcgtccaa tcccttgctg
    17521 gcagtcgcca cggagataat cgcttttatt ttccaaaaga aatgttggac caaaacagca
    17581 tctttgcaag cattacccag caatttttac acttgattga gaacgatcat tttaccccaa
    17641 ataaaaacta gaagaggaat tttatgagta ttaaactaat tgccgtcgat attgacggaa
    17701 ccctagtcaa cagccaaaag gaaatcactc ctgaagtctt ttctgccatc caagatgcca
    17761 aagaagctgg tgtcaaagtc gtgattgcaa ctggccgccc catcgcaggt gttgccaaac
    17821 ttctggacga cttgcagttg agagaccaag gtgactatgt ggtgaccttc aatggtgccc
    17881 ttgtccaaga gactgatact ggccatgaga ttatcagcga atccttgacc tatgaggatt
    17941 atctggatat ggaatttctc agtcgcaagc ttggtgttca catgcatgct attactaagg
    18001 acggtatcta taccgccaat cgcaatatcg gaacatacac tgtgcacgaa tcaaccctcg
    18061 tcagcatgcc tatcttctac cgcactcctg aagaaatggc tggcaaggaa attgtcaagt
    18121 gtatgttcat cgatgaacca gaaatcctcg atgctgcgat tgaaaaaata ccagccgaat
    18181 tttacgagca ctactctatc aacaaatctg ctcctttcta cctcgaactc cttaaaaaga
    18241 atgtagacaa gggttcagct attactcact tagctgaaaa actaggatta accaaagatg
    18301 aaaccatggc tatcggagac gaagaaaatg accgtgccat gctggaagtc gttggcaacc
    18361 ctgtagtcat ggaaaacgga aatccagaaa tcaaaaaaat cgccaaatac atcaccaaaa
    18421 caaatgacga atccggcgtt gcccatgcta ttcgtacatt ggtactgtaa aaggaaagaa
    18481 tagataaaaa ccgctcagct gagcggtttt tgatgtctaa ttactgcccc ctgcaggaat
    18541 cgaacctgca actactcctt aggagggagt tgttatatcc attgaactaa gggagctaga
    18601 taaaaactct gctgaaaagc agagtttttt agtcgaatta acgacggatt tctttgatac
    18661 gagctgcttt accttgaaga gcacgcaagt agtacaattt cgcacgacgt actttaccgt
    18721 aacgaacaac ttcgattttt tcaacacgtg gagtgtggat tgggaagata cgctcaacac
    18781 ctacaccgtt agagatttta cgaactgtgt agttttctga gattccagca cctttacgtg
    18841 cgataacaac accttcaaaa atctggatac gttcacggtt accttcgaca actttcgcgt
    18901 gtacacgaac agtgtcacca ggacggaatg atgggatatc tgtacgaagt tgaccttcag
    18961 tcaagctttg gattaatgga ttcattttat tctcctatct ttgtcaatct tgaggaatct
    19021 tcctcagcgg ataaactgta tttttgtgcg tccattacac acaagatata gtttaccaaa
    19081 tttctaaaaa aaagtaaaga aatttatagc aaaattccta aaaaaatcgc aaccaaacca
    19141 cctatgtaag tcaaagtcag gtaagaataa aagaccttct tatcacttag cagtctttga
    19201 agttcgtcat tcaaggtcga aaaagttgtt aaaccgccac aaaatcctgt tgctagaata
    19261 gcatatactt ccttagactc tacatgattg tagaatactc caattaaaaa acaacctaaa
    19321 agattagcta tgagcgttcc gagtggcaat ttagaagctt gattatagcg agaaaagaaa
    19381 taccgtacga gtgctccgaa accacaagca attgcaagat agacgattac catttcttcc
    19441 tccctagaaa ataagctaag agtaggcctc caccgatgct caaaagcaaa tacaggacta
    19501 aactaagata acgccctgta tcaagcagct tcacagtatc aagcattagg ctggaaaaag
    19561 ttgttaaacc tccgcaaaaa cccgtcccca gtgctaaaat caagccctta ctagtcccct
    19621 tatagaccag atagcccttg acaagaaaaa tcaagcagaa aattcccaga tagttgacaa
    19681 agagagtgcc ccaaggaaag tctggactgg ctggtaacca ggtggaaact agatatcgga
    19741 caagtccgcc caacatagca gctagaaaaa ttcctagcgg ataaaattgt tcttttttca
    19801 tttgatattt tgatcctgat aatcacgcga acgtttgagt atgtccgaaa aagtcgcgac
    19861 aatagtctcc tgatagcgct tgtcctctac acgactccta accttttcaa aaataacttc
    19921 ttctctctta gtatctaaaa tcggtttacc tgaagctttc ttataagcaa ccaccccctc
    19981 aactaaatgc attcgttctt ctaacagttt gacaatttgg tcgtcgattt gatcgatttc
    20041 ttgacgaata atatctaaat ccatacagtc tcctccttta tttgaattat tgtatcaaaa
    20101 agccatcaat taggctagta aaatcccaac tctcgataag aaaaatgcac tgattgatta
    20161 catcagcgca cttttatgtt tatcctactt tagcagccaa ttcttctgcg aattgttcca
    20221 agcgttcaat atcttcttcc tcggcagaaa gatcaacttt aacacactct gaaccttttt
    20281 ctgctcctgt tgacacaaag acacggtcaa agtcatcaac agccttacag aattcatcgt
    20341 agaaggtatc tcctgagccg accactccgt agattttgcc attcaagttg agatctgcta
    20401 ggtcttcgta gaagtccatc atctcatctg gcaattcacc atcaccataa gtataggtcg
    20461 caacgatagc gatgtctgct tccaagaagt ctgaagcgtc aacagttgta cattcatcaa
    20521 catcaacatc caagcccaag tcacgtaatt tgtctgctac aatatctgca atttcttcgg
    20581 tattaccggt catactggca aatacaattt ttgctaatgc catatcgtcc tcctcaattt
    20641 atctttctcc attatatcac atctttttca ttttaaaaat aaaaattctt gtgctacaat
    20701 gaaatgagaa agaattgagg ttatttatgg agatttgcca acaaatttta gaaaaaatta
    20761 aagaatacga caccattatc attcatcgtc atatgaaacc agaccctgat gccttgggaa
    20821 gtcaggtggg attgaaagcc ttgctggaac atcatttccc agaaaaaacc atcaaagccg
    20881 tcggttttga tgaaccaact cttacttgga tggctgagat ggatcttgtt gaagatagag
    20941 cctaccaagg cgcacttgtc atcgtctgtg atacagctaa tactgctcgt atcgatgata
    21001 agcgctatag tcaaggtgat tttctcatta agattgacca ccatccaaat gatgatgtat
    21061 acggtgacct gtcttgggtc gatactagtt caagtagcgc tagcgagatg attaccctat
    21121 ttgcccaaac aacccaacta gccttggcag atcgcgatgc tgagttgctc tttgcaggaa
    21181 ttgtcggtga tacaggtcgc ttcctctacc cttctaccac tgcacggact cttcgcctgg
    21241 ctgcttattt gagagaacat aactttgact ttgcggctct cactcgcaaa atggacacta
    21301 tgagctacaa aattgctaaa ctgcaaggct acatctacga ccatctggaa gtggatgaaa
    21361 atggtgctgc tcgcgttatc ctgagtcaga aaatcttgaa acaatacaat ataaccgatg
    21421 ctgaaactgc ggccattgta ggtgcacctg gacgcattga cagagtgagt ctctggggaa
    21481 tttttgtcga acaggctgat ggccactacc gagttcgctt acgcagtaaa gtccatccta
    21541 tcaatgaaat tgccaaggag catgatggtg gaggccaccc tctagcaagt ggtgctaatt
    21601 cctatagcct agaagaaaac gaaatcatct accaaaagtt aaaaaacttg cttaaaaact
    21661 gataaaatac ttgccaaact tttcagaatc tgatagacta gtatggtaac aatctatggc
    21721 tcgcaaagag accatggcag aaaggaaata ttgcaaaatg aaaaaagata tccatccaga
    21781 atatcgccca gttgtcttca tggacacaac tactggttac caattcctta gcggttcaac
    21841 aaaacgctct aacgaaacag ttgagttcga aggcgaaact tacccattga tccgtgtgga
    21901 aatttcatca gactcacacc cattctacac tggacgtcaa aagttcactc aagcagatgg
    21961 acgcgtggat cgtttcaaca aaaaatacgg tctcaaataa tgataagaga acagtttcgg
    22021 ctgttctttt ttgtttcttg aaatcaactg ctgttttcat gttccagact catctgtagg
    22081 tttggtttcc atgctactag gcaggaagga aatagctgtt tcaacacgtc cataatgagc
    22141 tgtactattg tcacgaacca cactttcatt gatggtccaa gtggaattca ttttcttaaa
    22201 agcttctcgg actttttcca aatctttgga ggcaatggcc tgctctaagg tttcaaaacg
    22261 aggacttaga cggtttacca atttttcctt ttccgcatct aggtcaacag gattttgttc
    22321 tttttcaaaa gctaatagag ctgaggaaat ttcggtgagt ttggcttcag taatatctcc
    22381 agatagagct aacttttcct taacaatctt accaacctca gaatccttat tttctactct
    22441 ttcgaagtct gatgccatct tcgtaacgag tttctgggtc tcagtctgac caccattttt
    22501 aaccgttttg gatgcatctg tgattttcac aaagaaaaaa ctcaagcttt cttgggcacc
    22561 tgctggggaa agaattaaaa atgacaaagc taaaactagt aaccagcttt tagccttcca
    22621 ataatttctg accaatgtag cctcctttct ccacaccacc aaagcaagta aaaagtccac
    22681 tacctatgtg agtgatgtat tcattcatct tatcagtagc acctaggtta gtttgaacct
    22741 taacaaagtt atcaggatcc ttctggaaag aaatgaagag caatcccgta tcaaactgac
    22801 cagtcttttc atcaatgcca tctgagtaag aataagaacg acgtaaaagt ggcttatcca
    22861 cttctttggc caaacaaaca tgcgaatcat caggtaagag actcaaatcc acttcatcaa
    22921 actcattttt cttaccaaag ggggcaccgc tttccttgta acgaccaaag gtattttctc
    22981 gttcttcgag actagtgcgg tcccaggtct ctaaaaacat ctgaatccga cgaactgcca
    23041 tataagaacc attttccatc cagtccttac tatcagccca gataacgcgg tcaaagtctt
    23101 gctccttggt tggatttgct gttccatcct taaaaccaaa gaggttccac ggagtctcca
    23161 ttcgatcccc gatagctgca aatccagact gactccaacg aaggggcacc gcatttctcc
    23221 ccttacggat gagattgcga atagcgtgaa aggcaatttg ctcatcatct gcacaagcat
    23281 gaatcacaat atctccacca gtatattttt cacgtaattg ctccttagga aatagaggta
    23341 aatccctgaa cagtcgaggg cgcttgtttt ccaagttcat ccttttcaag aaacttgcag
    23401 atacaccaaa agtcagcgtc aaacgatgag gattgagccc aactgtctca ccagtatcgc
    23461 tcggaggaaa gagagcattc tgtccatctt ttttaaccaa ttccccctcg accaacttgg
    23521 cactataatc cgtccaatcc ttgaatagct ggataatttt atctctatcc gtcgtatgca
    23581 ggtccaagac aacaaaatag atattctttt gcatgggcgt actatttggt acatcaagcg
    23641 aaccttatga aaaggtctac tggttttaaa gcgctttctt ttcttcttga attgagattt
    23701 tatttttaga cgcgacaatg gtttgagcgt ctgctttcct aggatgttct ggacgtggtg
    23761 taatatttcg ccaaccatgg cgcttcaaca gttgatagaa ggcatcacgt gtgtaggaac
    23821 gacctaactc ctttttataa gcctgaaata aggcatcaat tgtaacaaat tctcctgcct
    23881 ctgtagcctt caaatgacgg gcaagaaagg ctttctcttc ctcaactgtc atatatgcat
    23941 ggttacgacc accacgtgtt tcttgaagga gagagtcgag tccgaactcc tcatattttt
    24001 ttacatttcg ctaaatcgtt gtttgattac agtctaaaag ctctataatc tctttataag
    24061 atttgcccat cagacgaaat atagtagatt gaaactagaa tagtacacct ctacttctaa
    24121 aacattgtta gaaatcgatt tgactgtcct gatcgatttg ccctgttctt gtttcgtttt
    24181 actatagaac gatttgaagg cgtttatgat atttagctgt acgagagtct tttaaaagtg
    24241 ttttgatggc ttggatttct tctttagttg atttcatatc actattatat aatgcttttt
    24301 gattttagtc tggtataaat attgctttcc tccaaaatgg tcataatttt actagcaaat
    24361 ctaacatatc acggataaat taacaagtga tttctgaatt gctaaacatt ttcttttctt
    24421 atagcatacc atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg
    24481 tttttttatc tattttcaaa aaaaaccaaa aactgaattg aaagaatttt tagaaaattt
    24541 ctgttttttc tttacagtga aaaaaaattc tgctataatg tcttatgtaa taaaatatga
    24601 caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt gtttgaaact
    24661 gtaaaagctc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac
    24721 actttggaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt
    24781 attactgagc ctgagcgcgt gatttctttc cgtgttcctt gggttgaccg tgatggaaaa
    24841 gttcaagtaa accgcggcta ccgtgttcaa ttcaactcag ctgttggacc atataaaggc
    24901 ggacttcgtt tccacccaac tgtaaaccaa gggattttga aattcctcgg atttgaacaa
    24961 atctttaaaa acgtcttgac tggacttcct atcggtggag gtaaaggtgg atcagacttc
    25021 gatcctaaag gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa
    25081 ttgcaaaaac acatcggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga
    25141 cgtgaaattg gttaccttta cggtcaatac aaacgtctta accaatttga tgctggtgtc
    25201 ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac
    25261 ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag
    25321 aaagtcgtta tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa agcaactgaa
    25381 ctcggtgcaa ctgttatttc tgtttctgac tcaaatggtt atgtcatcga tgaaaatggt
    25441 atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt gactgagtat
    25501 gcagctgaaa aagcaactgc aacctaccac gaaggtactg tatggactta cgctggaaac
    25561 tatgacattg ctcttccatg tgccactcaa aacgaaatca acggtgaagc agctaaacgt
    25621 ttggttgctc aaggcgttat ctgtgtatct gaaggtgcca acatgccgag cgaccttgat
    25681 gccatcaaag tttacaaaga aaatggtatc ttctacggac ctgcaaaagc tgccaacgct
    25741 ggtggtgtag ccgtttcagc tcttgaaatg agccaaaaca gtcttcgcct ctcatggact
    25801 cgtgaagaag ttgatggcca tctcaaagac atcatgacaa acatcttcaa cacagctaaa
    25861 acgacttcag aaacatacgg tcttgataaa gactaccttg caggagctaa cattgctgcc
    25921 tttgaaaatg tagcaaatgc catgattgca caaggtattg tttaagattt atttactcaa
    25981 tcctcaatca ctacgattgg ggatttttag cttgaattaa aaaattggaa aatctaatta
    26041 aataaaatga aatgaaataa aaactgaaca aattgattgc ggaattcaaa ccaatttcta
    26101 acatacttct agaaattaat ttgacttttc taatcgattt gttcatatct tatttcaatt
    26161 tactatactt acttaaccct ttttatactc aatgaaaatc aaagagcaaa ctaggaagcg
    26221 agccgcaggc tgtacttgag tacggcaagg caaagctgac gtggtttgaa gagattttca
    26281 aagagtatta aacaaaaaga aaaaccgcta ctcctaagaa tagcgattta atcatgtttt
    26341 taagctacta ctgtagttgc tctattattt aagtgttatg aataacttca atatctttaa
    26401 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
    26461 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
    26521 tcaacaagcc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaacacta
    26581 ttccaatcat cacccctagt gaggctgttg ttaaaattac atattcattt tctttcttca
    26641 ttttctttac acctcatttc ctttttgtat ataagctgta gtactctcca ccaagctcca
    26701 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataatat
    26761 ccgcatcctt aatcgttgac aatctatgag ctacaattat ttgagtacag ccctgacttt
    26821 ttatatactt tgttattctt tcctcattaa tagtgtctaa agcactagtt gcttcatcta
    26881 aaattacaat actaggatta tttattaatg cacgtgccag tgctatccgt tgtctttgac
    26941 cacctgaaat atttgaaccc atctctgaga tgatagtatt aaatttcatc ggcatagcca
    27001 tgatttcatc atagatttga actgctttac aaacttcctc tatcttttgt gaagtaactt
    27061 cgttctttaa agttatatta tcaagaatac ttcggttcaa taaaaatgaa tcctgtggaa
    27121 ctactcctaa attttgactt aatatttttt tatctatttg attaatattt ataccatcaa
    27181 ataaaacttt tcctgtatca atcttatata atcctgatgg tatttttgat aatagacttc
    27241 ctgcaaaact agaatcctag ttcatgattg ataataccag cactcaaatt cattcgtaat
    27301 ccaaagcgtt tacgatgatt tcgataggtt gttgaaaaca ttttaaacgt ttttactttg
    27361 gcaaagatgt tctcaacctt gcttctatcc ttagatagtg catggttata ggttttatct
    27421 tcaactgtta gcggcttgag tttgctggat ttacgtggaa tttgtgcttg aggatatatc
    27481 ttcatgagcc cttgataatc actgtcagcc aagattttac cagcttgtcc gatatttctg
    27541 cgactcattt tgaacaactt catatcatga caatagttca cagcgatatc caaagaaata
    27601 attctccctt gacttgtgac aatcgcttga gtcttcatag cgtgaaattt ctttttacca
    27661 gaataattcg ctaattcttt ttttaggtcg attgattttt acttccgtcg catcaatcat
    27721 taccgtgtcc tcagaactga gaggagttct tgaaatcgca acaccacctt tgaacaagag
    27781 ttacttcaac ccattggctc cgacggatta agttgctttc gtgaatacca agatcagccg
    27841 caatttcttc ataagttcga tattctcgca catattgaag agtggccata agaaggtctt
    27901 ctaggcttaa tttaggtttt cgcccacctt ttgcgtgttt aagttgataa gctgttttta
    27961 atacagctaa catctcttca aaagtcgtgc gttgaacacc aacaagacgc ttaaatcgtg
    28021 catcggttag ttgtttactt gcttcataat tcatagaact attataccat attttgtttc
    28081 gca
//
LOCUS       DAVIME010000026        27337 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVIME010000026 DAVIME010000000
VERSION     DAVIME010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27337
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.026"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            62..316
                     /locus_tag="VV588_001225"
     CDS             62..316
                     /locus_tag="VV588_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU7083571.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            510..1844
                     /gene="trmFO"
                     /locus_tag="VV588_001226"
     CDS             510..1844
                     /gene="trmFO"
                     /locus_tag="VV588_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU7083572.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLSSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            1928..2665
                     /locus_tag="VV588_001227"
     CDS             1928..2665
                     /locus_tag="VV588_001227"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU7083573.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2674..3231
                     /gene="frr"
                     /locus_tag="VV588_001228"
     CDS             2674..3231
                     /gene="frr"
                     /locus_tag="VV588_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU7083574.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDIGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3291..4145
                     /gene="cvfB"
                     /locus_tag="VV588_001229"
     CDS             3291..4145
                     /gene="cvfB"
                     /locus_tag="VV588_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU7083575.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4154..4369
                     /locus_tag="VV588_001230"
     CDS             4154..4369
                     /locus_tag="VV588_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU7083576.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4455..5423
                     /locus_tag="VV588_001231"
     CDS             4455..5423
                     /locus_tag="VV588_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU7083577.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5492..6306
                     /locus_tag="VV588_001232"
                     /pseudo
     CDS             5492..6306
                     /locus_tag="VV588_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
     gene            complement(6271..6453)
                     /locus_tag="VV588_001233"
     CDS             complement(6271..6453)
                     /locus_tag="VV588_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083578.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     RLVRNLVHFIIDDGTN"
     gene            6489..6989
                     /locus_tag="VV588_001234"
     CDS             6489..6989
                     /locus_tag="VV588_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083579.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6992..7252
                     /locus_tag="VV588_001235"
                     /pseudo
     CDS             6992..7252
                     /locus_tag="VV588_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7619..8718)
                     /gene="ald"
                     /locus_tag="VV588_001236"
                     /pseudo
     CDS             complement(7619..8718)
                     /gene="ald"
                     /locus_tag="VV588_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072563.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8895..9464
                     /locus_tag="VV588_001237"
     CDS             8895..9464
                     /locus_tag="VV588_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083580.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            9532..10182
                     /locus_tag="VV588_001238"
     CDS             9532..10182
                     /locus_tag="VV588_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU7083581.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            10166..12406
                     /locus_tag="VV588_001239"
                     /pseudo
     CDS             10166..12406
                     /locus_tag="VV588_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
     gene            12585..12773
                     /locus_tag="VV588_001240"
     CDS             12585..12773
                     /locus_tag="VV588_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083582.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYARYEVINYYSGGY"
     gene            12806..13393
                     /locus_tag="VV588_001241"
     CDS             12806..13393
                     /locus_tag="VV588_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083583.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            13397..14581
                     /locus_tag="VV588_001242"
     CDS             13397..14581
                     /locus_tag="VV588_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083584.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASPGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKEFFN
                     RF"
     misc_feature    14745..14876
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14892..15422
                     /gene="infC"
                     /locus_tag="VV588_001243"
     CDS             14892..15422
                     /gene="infC"
                     /locus_tag="VV588_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU7083585.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            15455..15655
                     /gene="rpmI"
                     /locus_tag="VV588_001244"
     CDS             15455..15655
                     /gene="rpmI"
                     /locus_tag="VV588_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU7083586.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15707..16066
                     /gene="rplT"
                     /locus_tag="VV588_001245"
     CDS             15707..16066
                     /gene="rplT"
                     /locus_tag="VV588_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU7083587.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            16124..16504
                     /locus_tag="VV588_001246"
     CDS             16124..16504
                     /locus_tag="VV588_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU7083588.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16754..17554
                     /locus_tag="VV588_001247"
     CDS             16754..17554
                     /locus_tag="VV588_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU7083589.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            17565..18503
                     /locus_tag="VV588_001248"
     CDS             17565..18503
                     /locus_tag="VV588_001248"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU7083590.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPVIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            18545..20578
                     /locus_tag="VV588_001249"
     CDS             18545..20578
                     /locus_tag="VV588_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU7083591.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKEKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFH
                     IKENGNYADKEWIFENGHCYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     YSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(20639..22294)
                     /gene="pavA"
                     /locus_tag="VV588_001250"
     CDS             complement(20639..22294)
                     /gene="pavA"
                     /locus_tag="VV588_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU7083592.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQENKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            22399..22896
                     /gene="ybeY"
                     /locus_tag="VV588_001251"
     CDS             22399..22896
                     /gene="ybeY"
                     /locus_tag="VV588_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU7083593.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISSDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22877..23272
                     /locus_tag="VV588_001252"
     CDS             22877..23272
                     /locus_tag="VV588_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU7083594.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEILNSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            23289..24188
                     /gene="era"
                     /locus_tag="VV588_001253"
     CDS             23289..24188
                     /gene="era"
                     /locus_tag="VV588_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU7083595.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKIPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMLREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            24237..25061
                     /gene="mutM"
                     /locus_tag="VV588_001254"
     CDS             24237..25061
                     /gene="mutM"
                     /locus_tag="VV588_001254"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU7083596.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQIHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            25061..25666
                     /locus_tag="VV588_001255"
     CDS             25061..25666
                     /locus_tag="VV588_001255"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU7083597.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            25653..26852
                     /locus_tag="VV588_001256"
     CDS             25653..26852
                     /locus_tag="VV588_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEU7083598.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26852..27001
                     /gene="rpmG"
                     /locus_tag="VV588_001257"
     CDS             26852..27001
                     /gene="rpmG"
                     /locus_tag="VV588_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU7083599.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            27041..27274
                     /gene="secG"
                     /locus_tag="VV588_001258"
     CDS             27041..27274
                     /gene="secG"
                     /locus_tag="VV588_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU7083600.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
BASE COUNT         8058 a         5108 c         6178 g         7993 t
ORIGIN      
        1 tgcgctgaac accaacaaga cgcttaaatc gtgcatcagt tagttgttta cttgcttcat
       61 cattcataga actactatac catattttgt ttcgcaggaa gtctattgga aagtaagaaa
      121 tattgaagct gaggctatta gaagaaattg tgagcgtggt gctatttttt caggtaaaat
      181 aaaatatcac gaagattcac agtttaaagg agatcactat gttgaatgtt atgctgtttt
      241 agataatacg gttatagcaa gagatagaat aacagtccct atcgatccgt tatgtggaaa
      301 agattttata gagtagcata taattgattc ttaactggaa tactcactat ctctttacat
      361 caagaaaatg actaaacagg gaagtttgcc ttcttccctt tttttgttat actagtagaa
      421 gaaaaaatta gaaagatttg tgggtgtcaa acagcccagt ggggtgtttt aatatggact
      481 taggtcccac ccaaagaggt attagtgtcg tgtctcaatc ttatatcaat gttatcggtg
      541 ctggtttggc aggttctgaa gcagcttacc aaatcgcaga gcgtggtatt ccagttaaac
      601 tatatgaaat gcgtggtgtc aagtctacac cccagcataa aacagacaat tttgctgagt
      661 tggtttgttc caattctttg cgtggggatg ctttgacaaa tgcagttggt cttctcaagg
      721 aagaaatgcg tcgcttgggt tctgttatct tggaatctgc tgaggctaca cgtgttcctg
      781 caggtggtgc ccttgcagtg gaccgtgatg gtttctctca aatggtgacc gaaaaagttg
      841 ccaaccaccc cttgattgaa gtggttcgtg atgaaattac agaattgccg acagatgtta
      901 ttacggttat cgctactggt cctttgacaa gtgatgcctt ggctgaaaag attcatgctc
      961 ttaatgacgg tgctggtttt tatttctacg atgcggcagc gcctattatc gatgtcaaca
     1021 ctatcgatat gagcaaggtc tacctcaaat cacgttatga taagggagaa gcggcctacc
     1081 tcaatgcccc tatgaccaag caagaattta tggatttcca tgaagctttg gtcaatgcag
     1141 aagaagcacc gcttagttct tttgaaaaag aaaagtactt tgaaggatgt atgcctatcg
     1201 aagtcatggc caaacgtggc attaaaacta tgctttatgg ccctatgaag ccagtcggtc
     1261 ttgagtaccc agacgactat acaggacctc gtgatggaga atttaaaaca ccttatgcgg
     1321 ttgtgcaact tcgtcaggat aatgcagctg gtagcctcta caatattgtt ggtttccaga
     1381 cccacctcaa atggggagaa caaaagcgtg tcttccaaat gattccgggt cttgaaaatg
     1441 cggagtttgt ccgttatggt gtgatgcatc gcaattctta catggattca ccaaatcttc
     1501 ttgagcagac ttaccgttct aagaaacaac caaatctctt ctttgctggt caaatgacgg
     1561 gtgtggaagg ctatgttgag tcggcggctt caggcttagt tgcgggaatt aacgcagctc
     1621 gtctcttcaa ggaagaaagc gaggctattt tccccgagac gacagcgatt ggaagcttag
     1681 ctcattacat tacccatgcc gacagcaaac atttccaacc aatgaatgtc aattttggga
     1741 tcatcaagga gttggaaggc gagcgtatcc gtgataagaa ggctcgttat gaaaaaattg
     1801 cagagcgtgc ccttgccgac ttagaggaat ttttgactgt ctaatttttt tgaaagaatt
     1861 gctcatgata ctataaaaat cttagaaatt gtgataaaat aggtaggatg aaagaaggag
     1921 agtgaaaatg gcgaatccca agtataaacg tattttaatc aagttatcag gtgaagccct
     1981 tgccggtgaa cgtggcgtag ggattgatat ccaaacagtt caaacaatcg caaaagagat
     2041 tcaagaagtt catagcttag gtatcgaaat tgcccttgtt atcggtggag gaaatctctg
     2101 gcgtggagaa cctgcagcag aagcaggtat ggaccgtgtt caggcagatt acacaggaat
     2161 gcttgggact gttatgaatg ctcttgtgat ggcagattca ttgcaacaag ttggggttga
     2221 tacacgtgtt caaacagcta ttgccatgca acaagtggca gagccttatg tccgtggacg
     2281 tgcccttcgt caccttgaaa aaggccgtat cgttatcttt ggtgctggaa ttggttcacc
     2341 ttacttctcg acagatacaa cagcggccct tcgtgcagct gaaatcgaag cagatgccat
     2401 cctcatggct aaaaatggtg tcgatggtgt ttacaatgcc gatcctaaga aagataagac
     2461 agctgttaag tttgaagaat tgacccaccg tgacgttatc aataaaggtc ttcgtatcat
     2521 ggactcaaca gcttcaaccc tctcaatgga caacgacatt gacttggttg tattcaacat
     2581 gaaccaacca ggcaacatca aacgtgtcgt atttggtgaa aatatcggaa caacagtttc
     2641 aaataatatc gaagaaaagg aataagaaag aatatggcta acgcaattat tgaaaaagct
     2701 aaagagagaa tgacccagtc tcaccaatca cttgctcgtg aatttggtgg tatccgtgct
     2761 ggtcgtgcca atgcaagctt gcttgaccgt gtacatgtag aatactatgg agtcgaaact
     2821 cctcttaacc aaatcgcttc aattacgatt ccagaagcgc gtgttttgtt ggtaacacca
     2881 tttgacaagt cttcattgaa agacatcgaa cgtgccttga acgcttctga tattggtatc
     2941 acaccggcta atgacggttc tgtgattcgc ttggttatcc cagctcttac agaagaaact
     3001 cgtcgtgacc ttgctaaaga agtgaagaag gtcggcgaaa atgctaaagt ggctgtccgc
     3061 aatatccgtc gcgatgctat ggacgaagct aagaaacgag aaaaagcaaa agaaatcact
     3121 gaagacgaat tgaagactct tgaaaaagac attcaaaaag taacagacga tgctgttaaa
     3181 cacatcgacg acatgactgc taacaaagag aaagaacttt tggaagtcta aaaataaaca
     3241 gaaaaactca gttggcattg ctggctgagt tttattcgaa agaaggaaat atgaatacaa
     3301 atcttgcaag ttttatcgtt ggactgatca tcgatgaaaa cgaccgtttt tactttgtgc
     3361 aaaaggatgg tcaaacctat gctcttgcta aggaagaagg ccaacataca gtaggggata
     3421 cggtcaaagg ttttgcatac acggatatga agcaaaaact ccgcctgaca accttagaag
     3481 tgactgccac tcaggaccaa tttggttggg gacgtgtcac agaggttcgt aaggacttgg
     3541 gtgtctttgt ggatacaggc cttcctgaca aggaaatcgt tgtgtcactc gatattctcc
     3601 ctgagctcaa ggaactctgg cctaagaagg gcgaccaact ctacatccgt cttgaagtgg
     3661 ataagaaaga ccgtatctgg ggcctcttgg cttatcaaga agacttccaa cgtcttgctc
     3721 gtcctgccta caacaacatg cagaaccaaa actggccagc cattgtttac cgtctcaagc
     3781 tgtcaggaac ttttgtttac ctaccagaaa ataatatgct tggttttatt catcctagcg
     3841 agcgttacgc agagccacgt ttggggcaag tattagatgc gcgcgttatt ggtttccgtg
     3901 aagtggaccg cactctgaac ctctccctca aaccacgctc ctttgaaatg ttggaaaacg
     3961 atgctcagat gattttgact tatttggaaa gcaatggcgg tttcatgacc ttaaatgaca
     4021 agtcatctcc agacgacatc aaggcaacct ttggcatttc taaaggtcag ttcaagaaag
     4081 ctttaggtgg tcttatgaag gctggtaaaa tcaagcagga ccagtttggg acagagttga
     4141 tttagggagg cttatgagaa aatcatttta cacttggctc atgaccgagc gcaatcctaa
     4201 aagtaacagt cccaaagcaa ttttggcaga cctcgctttt gaagagtcag cctttccaaa
     4261 acacacagat gattttgatg aggtcagtcg ctttttggag gagcatgcca gtttctcttt
     4321 taacctagga gattttgaca gcatttggca ggaatatcta gaacactagc atttattcat
     4381 tgggtttggg ctagtaattt ctccatccct ctgctataat aaaaagaaat aaaaggatta
     4441 gagaggttct ttatttgaag gaacattcaa tagacattca actgagtcat ccagatgacc
     4501 tgtttcatct ttttggttcc aatgaacgcc atcttcgttt gatggaagaa gagcttgatg
     4561 ttgtgattca tgctcgtacg gagattgtcc aggttttggg agaagagtct gcctgtgagg
     4621 aagcccgtca agttattcag gctttgatgg tcttggtaaa tcgtgggatg accgttggta
     4681 cgccagatgt agtcactgcg attagcatgg tcaaaaatga tgaaattgac aagtttgtcg
     4741 ccctttacga agaagaaatt atcaaagata atactgggaa acctatccgt gtcaaaaccc
     4801 tagggcaaaa gctttatgtg gacagtgtca aacagcatga tgtgaccttt ggaattgggc
     4861 cagcaggtac agggaagacc ttccttgcag tgaccttggc agtgactgcc cttaaacgtg
     4921 ggcaagtcaa gcgaattatc ctaactcgtc cagcggtgga agcgggagag agtcttggat
     4981 ttcttccggg tgatcttaag gagaaggtgg atccttacct tcgtcctgtt tacgatgcct
     5041 tgtatcaaat tcttgggaaa gaccaaacga ctcgtctcat ggagcgtgaa attatcgaaa
     5101 ttgcgcccct tgcctatatg cgtggccgga ccttggatga tgcctttgtc attctcgatg
     5161 aggcgcaaaa cacgaccatc atgcagatga agatgttctt gacgcgttta ggttttcatt
     5221 ctaagatgat tgtcaatgga gatattagtc agattgacct gccacgtaat gtcaagtccg
     5281 gtttgattga tgctcaagag aaactcaaga acatccatca gattgacttt gttcattttt
     5341 cagccaagga tgtggttcgc catcctgttg tcgctcagat tatccgagcc tatgaatatt
     5401 ctactgaagt tgcacacgac tgattttgag gaagttcgcc tgcaaaagaa tagacttgtt
     5461 cggtaactgt aaaaagtgtt atactatttt tatggaaaca gtatacgaca aagcacaaaa
     5521 acttaactca aaaaacttca aactattgat tggtgtcaaa aaggaaacct ttcaactcat
     5581 gctagaacac ctgaattcag cctatcagat tcagcaccga aaaggtggac gtccacgtag
     5641 tctgcccatg gaagaccagc tcattatgac cctccgttac ttgcgatatt atcccactca
     5701 gcgtctgctg gcctttgatt ttggcgtcgg tgtagctacg gtaaatgcca tcatcacttg
     5761 ggtggaggat acacttcgtg cgtcaggtag ctttgatttg gaccatttag aagccccgag
     5821 tgctgctgtg gctattgacg tgaccgaaag tccgattcag cgtccaaaca aaaccaaagc
     5881 aaaaattatt ctggtaaaaa gaaacgacac accttaaaaa ctcaaattat gctggatttg
     5941 acgacacata aagtctgtca aatggccttt tctgacggac atacgcatga ttttactctc
     6001 ttcaaagaaa gtattggaca aagtttgcct gaaacgacgc ttgcctttgt tgacctaggt
     6061 tatttaggca tcttgaaatt tcatgagaat actttcattc ctgctaaaaa ttccaaaaat
     6121 cgccgcctga gtgaggatga taagcagtta aataaagaga tgtcagcgat acgaattgaa
     6181 attgaacatt ttaacgctaa attcaagacc ttccaaatca tgtcagtccc ttatcgtaac
     6241 cgcagaaaac gtttcgagtt acgggcggaa ttaatttgtg ccatcatcaa ttatgaagtg
     6301 aactagattc cgaacaagtc taatatactt ttgagagagg aaaatccagt tgtataggct
     6361 aaaggtttta tccaaaggtc tgagacaacg attaggcacg atggaaagaa cttttatgtg
     6421 gctgatgacg atcagtgcat cttcctgtgt cataatcaca gggcacaaga aagtaggaat
     6481 ttgaaaagat gattgaccaa ctatctaagt attacagttg taggatacta actgaaaagg
     6541 atattccaag tattttatct ttatatgaaa gtaatcctct gtattttcag cattgtccac
     6601 cagagccaaa ttttgcaact gtaaaagagg acatgctttg tctacctgaa ggtaaagcta
     6661 aggctgataa gttttttgtt ggattttgga atggatctga ccttgtggct gttatggatt
     6721 ttgtctatgc atatcctgat gaggagactg tttttattgg tttgtttatg gttgatcaag
     6781 cctatcagag aaaagggatt ggtagtcata ttgtgacaga agcactagct tattttgcta
     6841 agaactttcg aaaggcacgt ttggcttatg ttaagggaaa tccgcaatct cagcattttt
     6901 gggaaaagca gggctttaaa tcaattggat gcgaggttaa gcaagaactc tatacggttg
     6961 ttatcgctga acagagccta gaagattaga aatggcatca agtaagaact atttggaatt
     7021 tgttttggaa caattatcag gattagatga tgtgacttac cgttccatga tgggggagta
     7081 tattctttac ttccgcggca agattattgg cggcatttat gacgatcgct ttttagttaa
     7141 acccgtgcaa gcagtcttag ataagattga ccaatcttct tttgagtttc catacaaagg
     7201 tgccaaagaa atgatttgag tggaagaact tgataataag atgtttctat aagacctaat
     7261 tttagctatg tataaccaac tgccaacgcc caaacctaaa aagaaaaagc aagggtgaac
     7321 gaagtaaaaa agaagtctgc taaggccctg tctttgcacg ggtaaaattt tatatataaa
     7381 aagaagctgg gactaaagag ctcagcttcc tttggtttat ataattgtca ttacaagacg
     7441 aagtggttgg gcgaaactct gttgacttta ttcaatttag agtttcttat gcacaattga
     7501 gtctggaacg aaagtctcca gttgcaaagt atacagtaca ataaaccaac gatgtaatag
     7561 ctgatgacac aaagcacagt gggtaggact tgcgaagtca cccttttctt ttcaaaattt
     7621 atactaaatc attgatatca gtgtagtcac gattaagtcc ttgagcaact ggtaggttag
     7681 tcaagtaacc ttgataagta gtcacacctt gacgcaagcc ttcatcttca gagattgctt
     7741 gtgcgaatcc tttgccagcc aaagcttcga tataaggaag agtgacattg gttagggcga
     7801 tggttgaagt gcgagcaacc gcaccaggga tattggcaac ggcatagtgg agaacaccgt
     7861 gtttttcata gacgggttca tcgtgcgttg tcacacggtc agctgtttcg ataacgccac
     7921 cttggtcaac agcaacgtca acgatacaga gcctggacgc atttgtttga ccatctcatc
     7981 tgtcaccaat tccggtgctt ttgcaccagg gatgagaatg gctccaatca ccacatcagc
     8041 atctctcaca cttgcttcaa tgttgaatga attagacata agagtttgaa tttgacttcc
     8101 aaagacttct tctagaactg agagacgctt ggaactaata tctaaaatag tcacttgagc
     8161 accaagacca agggcgatgc gggcagcatg tgtaccgacg acaccaccac cgatgatagt
     8221 tacttttcct tttggaacac ctggtacacc accaagtaga acaccagagc caccagcttg
     8281 cttagtaagg aagtgagctc cgatttgaac agccatacga cctgcaacct cactcatagg
     8341 aacgaggagc ggtagttgtc cttgattgtc acgaacagtt tcagttgttt ttgctgttaa
     8401 catagcatct gctaattctg gagcagcggc catgtgcaag taggtgaaga gaagaagatc
     8461 gtcgcgcaag taaccgtatt cagaacttaa agattctttt actttcacaa ccaactctgc
     8521 tgcccaagct tcaccagcag tagcgacaat ctcagctcct tgcttttgat agtcagcatc
     8581 agtaaagcca gaaccgagac cagcatttgt ttcgataagg acacgatgac cacgactaac
     8641 taagctatga acacctgcag gtgtgagggc gacacggttt tcgttatttt taatttcttt
     8701 tgggattccg attaacattg agataaccta cctttcaatt gacggtcttg ttttggttgt
     8761 cacattccag ttcataaatc aaaaatgtga cggtttcatt gtatatgaaa ccgcttcaaa
     8821 aatcaagaaa aacttgtcat ccaaattttt ttatgctaga ctagtgaaaa tcaagctcta
     8881 atggagggaa aagtatggaa tcaatatttg tgaaatttgc ccagtatccg tctatagaaa
     8941 cggagcgttt attgctcaga cctgtaactt tggatgatgc ggaagcaatg tttgactatg
     9001 cctcggacaa gggtaataca cgttacactt ttccaaccaa tcaaagcttg gaagaaacca
     9061 agaataacat tgctcagttc tacttggcta atcccttggg acgttgggga atagaactaa
     9121 aaagcaatgg tcagtttatt ggaaccattg acttgcacaa gattgattct gttcttaaga
     9181 aggcagctat tggctacatt atcaataaaa agtattggaa tcaaggatta acgacagaag
     9241 ccaatcgtgc tgtgattgag ctagcttttg agaagatagg gatgaataag ttgactgccc
     9301 ttcacgataa ggctaatccc gcgtcaggaa aggtcatgga gaaatcaggc atgcgttttt
     9361 cccatgcaga accatatgct tgtatggacc agcatgaaaa aggccgaatc gtgacaagag
     9421 ttcattatgt cttgaccaag gaagactatt ttgcaaataa ataagcagtt gaaaagaaat
     9481 ttttcgactg ttttttcttc ctcttacgaa taatctaaga gaggagaaaa tatggaagca
     9541 attatcgaga aaatcaaaga gtataaaatc atcgtcatct gtactggtct gggcttgctt
     9601 gtaggaggat ttttcctgct aaaaccagct ccacaaacac ctgtcaaaga gacgaatttg
     9661 caggctgaag ttgcagctgt ttccaaggac tcatcgaccg aaaaggaagt gaagaaggaa
     9721 gaaaaggaag aaccccttga acaagatcta atcacagtag atgtcaaagg tgctgtcaaa
     9781 tcgccaggga tttatgactt gcctgtaggt agtcgagtca atgatgctgt tcagaaggct
     9841 ggtggcttga cagagcaagc agacagcaag tcgctcaatc tagctcagaa agttagtgat
     9901 gaggctctgg tttacgttcc tactaaggga gaagaagcag ttagtcaaca gactggttcg
     9961 gggacagctt cttcaacaag caaggaaaag aaggtcaatc tcaacaaggc cagtctggaa
    10021 gaactcaagc aggtcaaggg actgggagga aaacgagctc aggacattat tgaccatcgt
    10081 gaggcaaatg gcaagttcaa gtcagtagac gagctcaaga aggtctctgg cattggtggc
    10141 aaaacaatag aaaagcttaa agactatgtt acagtggatt aagaatttct ctattcccct
    10201 aatttacctg agttttctat tactttggct ttattacgct attttctcag catcttatct
    10261 tgctttgttg ggctttgttt ttctgctagt ctgtctcttt atccaatttc cgtggaaatc
    10321 tgctggtaaa gttctaataa tttgcggaat ctttggattt tggtttgttt ttcaaaattg
    10381 gcaacagagt caagcgagtc aaaatctggc ggattctgtt gaaagggtac ggattttgcc
    10441 tgatactatt aaggttaatg gtgatagtct atcctttcgt ggcaagtcta acggtcgtgc
    10501 tttccaagtc tattataaac tccagtccga ggaggagaaa gaagcctttc aagctttaac
    10561 tgacctgcat gagataggac tagaagggaa gctttcggag ccagaagggc agagaaattt
    10621 tggtggcttt aattaccaag cctatctgaa gactcaggga atttaccaga ctctcaatat
    10681 caaaacaatc cagtcacttc aaaagattgg cagttgggat ataggagaaa acttgtccag
    10741 tttacgtcga aaggctgtgg tttggattaa gacgcacttt ccagacccta tgggcaatta
    10801 catgacagga ctcttgctgg gacatctgga caccgacttt gaggagatga atgagcttta
    10861 ttccagtcta ggaattatcc acctctttgc cctatctggc atgcaggtag gttttttcat
    10921 gaatggattt aagaaacttc tcttgcgatt gggcttgacc caagaaaagt tgaaatggct
    10981 gacttatccc ttttccctta tctatgcggg actaactgga ttttcagcat cggttattcg
    11041 cagtctcttg caaaagctac tggctcaaca tggggttaag ggcttggata attttgcctt
    11101 gacggtgctt gtcctcttta ttgtcatgcc aaactttttc ttgacagcag gaggagtctt
    11161 gtcctgcgct tatgctttta tcctgaccat gaccagcaaa gaaggggagg ggctcaaggc
    11221 tgttactagt gaaagtctag tcatctcctt gggcatattg cccattctat ccttctattt
    11281 tgcggaattt caaccttggt ctatcctttt gacctttgtc ttttcctttc tttttgactt
    11341 ggtcttctta ccgctcttgt ctatcttatt tgtcctttcc tttctctatc cagtcattca
    11401 gctgaacttt atctttgaat ggttagaggg cattattcgc ttggtctcgc aggtggcaag
    11461 gagaccactt gtctttggtc aacccaacgc atggctttta atcttattgt taatttcctt
    11521 ggctttggtc tatgatttga ggaaaaacat taaaggatta acagtattga gtttattgat
    11581 tacaggtctc tttttcctta ccaagtatcc actggaaaat gaaatcacca tgctggatgt
    11641 ggggcaagga gaaagtattt tcctacggga tgtaactggg aaaaccattc tcatagatgt
    11701 aggtggtaag gcagaatctt ataagaaaat caaaaaatgg caagaaaaga tgacgaccag
    11761 caatgcccag cgaaccttga ttccctatct caaaagtcga ggagtagcta agattgacca
    11821 gctaattttg actaacacgg acaaggagca tgttggagat ttgtcagaga tgaccaaggc
    11881 tttccatgta ggggagattc tagtatcaaa agacagtctg aaacagaagg aatttgtggc
    11941 agaactacag gcgactcaaa caaaggtgcg tagtatgata gtaggggaga acttgcccat
    12001 ttttggaagt cagttagaag ttctatctcc aaggaaaatg ggagatggag gacacgatga
    12061 taccctagtt ctgtatggga aattcttgga taagcaattt ctcttcacgg gaaatttgga
    12121 ggagaaagga gagaaggact tgctgaagca ctatccagac ttgaaagtaa atgttttgaa
    12181 agctagccaa catggcaata aaaaatcatc aagtccagcc tttctagaaa aactcaaacc
    12241 agagcttact cttatctcag ttggaaagag caattgaatg aaactccccc atcaggaaac
    12301 attgacacga ctggaaggta tcaatagcaa agtttatcga actgaccagc aaggagctat
    12361 acgttttaag gggttggata gttggaaaat cgaaagtgtt cgataggaag gataaatgtt
    12421 gtagattagt gaaataaact aaaaatttgt tgcataataa tgataaaaat ggtataatga
    12481 aaacgtattc aatattgagg atataaaatc attaaaaatc agcaaaagtt gttttattag
    12541 ttagtttata atctattggt cttcttcagt ccagtgtatc tgctgtgaca gtcactaaaa
    12601 gttacaagta tgattggaat acggtttggg aatatagtac caactatcac gaccatcagt
    12661 atgcttggat tccgtcatgg tctcgttatg acagctattc tgagtataaa gttggcggag
    12721 gctggaacta cgctcgttat gaggtcataa actattacag cggaggctat taattcttaa
    12781 agagtgagaa aaaggagggc tagatatgtt gcagcttact catgtgacct taaaaacgcg
    12841 acaagtcatc ttgcaagatg tggatttcac ctttaaaaag ggtagggttt atggtcttct
    12901 tgctatcaat ggctctggaa agacgaccct gttccgtgcc attagcaatt taattcccat
    12961 aagtagtgga aatatcgcag cccctccttc tttattttat tatgagagta ttgaatggct
    13021 ggatggaaac ttaagtggga tggactacct tcgtcttatc aaaaacatct ggaagtcagg
    13081 tctgaacttg agggatgaaa tcgcctattg ggaaatgtct gactatatca gtcttcccat
    13141 tcgcaagtat tccttaggca tgaagcaacg cttggtgatt gccatgtatt tcctcagtca
    13201 ggccaaatgc tggctcatgg atgagattac aaatggctta gatgagtatt atcgacagaa
    13261 gttttttgat aggctagcac aaatcgatag acaagaacag ctggttcttt taagttccca
    13321 ctataaggaa gagttggttg atgtctgcga tagagtagta accattcatc aggggcagat
    13381 agaagaggtt tagtttatga aagatgttag tctattttta ttgaaaaaag ttttcaaaag
    13441 ccgcttaaac tggattgtct tagctttatt tgtatctgta ctcggtgtta ccttttattt
    13501 aaatagtcag actgcaaact cacacagctt ggagagcagg ttggaaagtc gcattgcagc
    13561 caacgagagg gctatcaatg aaaatgaaga gaaactctcc caaatgtctg ataccagctc
    13621 ggaggaatac cagtttgcta aaaataattt agacgtgcaa aaaaatcttt tgacgcgaaa
    13681 gacagaaatt ctgactttat taaaagaagg gcgctggaaa gaagcctact atttgcagtg
    13741 gcaagatgaa gagaagaatt atgaatttgt atcaaatgac ccgactgcta gccctggctt
    13801 aaaaatgggg gttgaccgcg aacggaagat ttaccaagcc ctgtatccct tgaacataaa
    13861 agcacatact ttggagtttc cgacccacgg gattgatcag attgtctgga ttttagaggt
    13921 tatcatccca agtttgtttg tggttgctat tatttttatg ctaacacaac tatttgcaga
    13981 aagatatcaa aatcatctgg acacagctca cttatatcct gtttcaaaag tgacatttgc
    14041 aatatcctct cttggagttg gagtgggata tgtaactgtg ctgtttatcg gaatctgtgg
    14101 cttttctttt ctagtgggaa gtctgataag tggttttgga cagttagatt atccctaccc
    14161 aatttatagc ttagtgaatc aagaagtaac tattgggaaa atacaagatg tattatttcc
    14221 tggcttgctc ttagctttct tagcctttat cgtcattgtg gaagttgtgt acttgattgc
    14281 ttactttttc aagcaaaaaa tgcctgtcct ctttctttca ctcattggga ttgttggctt
    14341 attgtttggt atccaaacca ttcagcctct tcaaaggatt gcacatctga ttccctttac
    14401 ttacttgcgt tcagtggaga ttttatctgg aagattacct aagcagattg ataatgtcga
    14461 tctaaattgg agcatgggaa tggtcttact tccttgcctg attatctttt tgctattggg
    14521 aattctattt attgaaagat ggggaagttc acagaaaaaa gaatttttta atagattcta
    14581 gctttcctat aggtagggaa aataagtaaa aactaacata gagagggaat caacttgatt
    14641 ctctcttttt gattcgaaaa ccaaaccaaa atacaaacac aaacttttca aaaaataact
    14701 ttttatcttg acaagagcta gaaaacttgg tatcatataa aagttgagaa aagcagaagt
    14761 gagagcttct cgccttgtga cattaagttg cctggcccta cggatgaaaa gtttcgaaga
    14821 aacgctatca taacgtgcgg gcttgtatat ttacaagtcc gctattgttt ttctctaata
    14881 aaacaaaaga ggtgaaaacc atagcaaagc aagacttatt catcaatgat gagattcgtg
    14941 tacgtgaagt tcgcttgatt ggtcttgaag gagaacagct aggtatcaag ccactcagtg
    15001 aagcgcaagc tttggctgat aacgctaatg ttgacctagt attgattcaa ccccaagcca
    15061 aaccgcctgt tgcaaaaatt atggactacg gtaagttcaa atttgagtac cagaagaagc
    15121 aaaaagaaca acgtaaaaaa caaagcgttg ttactgtgaa agaagttcgt ctaagtccaa
    15181 caattgacaa gggtgacttt gatacaaaac ttcgtaatgc acgtaagttc cttgaaaaag
    15241 gaaataaagt taaggtatct attcgcttta agggtcgtat gattacccat aaagagattg
    15301 gtgcaaaagt tttagccgag tttgctgaag caactcaaga tattgccatc atcgaacaac
    15361 gtgctaaaat ggatggacgt caaatgttca tgcaattggc gccagcgact gacaaaaaat
    15421 aattgtcaga aagttaaata aaggagaaaa aatcatgcca aaacaaaaaa cacaccgcgc
    15481 atcagctaaa cgtttcaaac gtacaggttc tggtggactt aaacgtttcc gtgcttacac
    15541 ttctcaccgt ttccacggaa aaactaagaa acaacgtcgt catcttcgta aagcatctat
    15601 ggtgcattca ggagattaca aacgtatcaa agcaatgctt actcgcttga aataatagct
    15661 tgactgtaag taaacaattc taggaaatat ttggaggaaa taaaacatgg cacgtgttaa
    15721 aggtggcgtt gtatcacgca aacgtcgtaa acgtattctt aaattagcaa aaggttacta
    15781 tggagctaaa cacatcttgt tccgtactgc aaaagaacaa gtaatgaact cttactacta
    15841 tgcataccgt gaccgtcgtc agaaaaaacg tgacttccgc aaattgtgga tcactcgtat
    15901 caatgcggca gctcgtatga acggactttc atactcacaa ttgatgcatg gtttgaaatt
    15961 ggctgagatc gaagttaacc gtaaaatgct tgctgacttg gctgttaacg atgcagtagc
    16021 tttcacagct cttgcagatg cagctaaagc aaaacttggt aaataacaac tgatgagact
    16081 ggaacaggat tgtccagtct ttttaaaaat aaaggagaaa agtatggctt caaaaatgct
    16141 acacacttgc ttacgagtag aaaatcttga aaaatcaatt gcattctatc aagatgcttt
    16201 tggttttaaa gaattgcgtc gcagagattt tccagaccat gccttcacga ttgtctatct
    16261 aggtcttgag ggtgatgatt atgagttgga gttgacttat aactacgatc acggtccgta
    16321 tgtggttggt gatgggtttg cccatatcgc cctcagtaca cctgatcttg aggcacttca
    16381 tcaagaacac agtgcaaaag gctatgaagt gactgagcca aatggtctac caggaactac
    16441 accaaactat tactttgtca aagaccctga tggatataag gtcgaagtca ttcgtgaaaa
    16501 ataatttcgt gcaagttaag tagaatattc gttttctact tgactttttt tagctgaaag
    16561 agtatactaa taaaaattca acctttaagg ggagtccaga gagactcaca aggtgtcaga
    16621 taaaagaata gtgcaatttt ctagaggaga ctttttgagt gtgctctctt gtgttgtacg
    16681 attttaactg aggccttgca ctagcaaggt cttttcttta tctggtcccc ttaaaattta
    16741 aggaggaaaa gttatgaatc ccacatgtaa gaagcgtttg ggtgtcattc ggttggaaac
    16801 catgaaggtg gttgcacaag aggaaatcgc gccagcaatc tttgaattag ttctagaagg
    16861 agaaatggtt gaagccatgc gagcaggcca atttcttcat ctgcgtgtac cggacgatgc
    16921 ccatctctta cgtcgtccta tttcaatttc gtctattgac aaggcaaaca agcagtgtca
    16981 cctcatttat cggattgagg gagctgggac tgcaattttt tcaaccttaa gtcagggaga
    17041 cactcttgat gtgatggggc ctcagggaaa tggttttgac ttgtctgacc ttgatgagca
    17101 gaatcaggtt ctccttgttg gtggtgggat tggtgttcca cccttgcttg aggtggccaa
    17161 ggaattgcat ggacgtggag tgaaagtagt gacagtcctc ggttttgcta ataaggatgc
    17221 tgttattttg aaaacggaat tggctcagta tggtcaggtc tttgtaacga cagatgatgg
    17281 ttcttatggc atcaagggaa atgtttccgt tgttatcaat gatttagata gtcagtttga
    17341 tgctgtttac tcgtgtgggg ctccaggaat gatgaagtat atcaatcaaa cctttgatga
    17401 tcacccaaga gcctatttat ctctggaatc tcgtatggct tgtgggatgg gagcttgcta
    17461 tgcctgtgtt ctaaaagtac cagaaagcga gacggtcagc caacgcgtct gtgaagatgg
    17521 tcctgttttc cgcacaggaa cagttgtatt ataaggagaa aattatgact acaaatcgat
    17581 tacaagtgtc tctacctggt ttggatttga aaaatccgat tattccagca tcaggctgtt
    17641 ttggctttgg acaagagtat gccaagtact atgatttaga ccttttaggt tctattatga
    17701 tcaaggcgac aacccttgaa ccacgttttg ggaatccaac tccaagagtg gcagagacgc
    17761 ctgctggtat gctcaatgca attggcttgc aaaatcctgg tttagaggtt gttttggctg
    17821 aaaagctacc ttggctggaa agagaatatc caaatcttcc tattattgcc aatgtagctg
    17881 gtttttcaaa acaagagtat gcagctgttt ctcatgggat ttccaaggca actaatgtaa
    17941 aagctatcga gctcaatatt tcttgtccca atgttgacca ctgtaatcat ggacttttga
    18001 ttggtcaaga tccagatttg gcttatgatg tggtgaaagc agctgtggaa gcctcagaag
    18061 tgccagttta tgtcaaatta accccgagtg tgaccgatat cgttactgtc gcaaaagctg
    18121 cagaagatgc gggagcaagt ggcttgacca tgatcaatac tctggttgga atgcgctttg
    18181 acctcaaaac cagaaaacca atcttggcca atggaacagg tggaatgtca ggtccagcag
    18241 tctttccagt agccctcaaa ctcatccgcc aagtagccca aacaacagac ctgcctatca
    18301 ttggaatggg gggagtggat tcggctgaag ctgccctaga aatgtatctg gctggggcat
    18361 ctgctatcgg agttggaaca gctaacttta ccaatcctta tgcctgtcct gtcatcatcg
    18421 aaaatttacc aaaagtcatg gataaatacg gtattagcag tctggaagaa ctccgtcagg
    18481 aagtaaaaga gtctctgagg taaactgcaa tcaatctgtt cttgattttt tattagtttg
    18541 taatatgaat ttaggagaat tttggtacaa taaaataaat aagaacagag gaagaaggtt
    18601 aatgaagaaa gtaagattta tttttttagc tctgctattt ttcttagcta gtccagaggg
    18661 tgcaatggct agtgatggta cttggcaagg aaaacagtat ctgaaagaag atggcagtca
    18721 agcagcgaat gagtgggttt ttgatactca ttatcaatct tggttctata taaaagcaga
    18781 tgctaactat gctgaaaatg aatggctaaa gcaaggtgac gactattttt acctcaaatc
    18841 tggtggctat atggccaaat cagaatgggt agaagacaag ggagcctttt attatcttga
    18901 ccaagatgga aagatgaaaa gaaatgcttg ggtaggaact tcctatgttg gtgcaacagg
    18961 tgccaaagta atagaagact gggtctatga ttctcaatac gatgcttggt tttatatcaa
    19021 agcagatgga cagcacgcag agaaagaatg gctccaaatt aaagagaagg actattattt
    19081 caaatccggt ggttatctac tgacaagtca gtggattaat caagcttatg tgaatgctag
    19141 tggtgccaaa gtacagcaag gttggctttt tgacaaacaa taccaatctt ggtttcacat
    19201 caaagaaaat ggaaactatg ctgataaaga atggattttc gagaatggtc actgttatta
    19261 tctaaaatcc ggtggctaca tggcagccaa tgaatggatt tgggataagg aatcttggtt
    19321 ttacctcaag tttgatggga aaatagctga aaaagaatgg gtctacgatt cttatagtca
    19381 agcttggtac tacttcaaat ccggtggtta catgacagcc aatgaatgga tttgggataa
    19441 ggaatcttgg ttttatctca aatctgatgg gaaaatagct gaaaaagaat gggtctacga
    19501 ttctcatagt caagcttggt actacttcaa atctggtggt tacatgacag ccaatgaatg
    19561 gatttgggat aaggaatctt ggttttacct caagtctgat ggcaaaatgg ctgaaaaaga
    19621 atgggtctac gattctcata gtcaagcctg gtactacttc aaatctggtg gctacatggc
    19681 gaaaaatgag acagtagatg gttatcagct tggaagcgat ggtaaatggc ttggaggaaa
    19741 agctacaaat aaaaatgctg cttactatca agtagtgcct gtcacagcca atgtttatga
    19801 ttcagatggt gaaaagcttt cctatatatc gcaaggtagt gtcgtatggc tagataagga
    19861 tagaaaaagt gatgacaagc gcttggctat tactatttct ggtttgtcag gctatatgaa
    19921 aacagaagat ttacaagcgc tagatgctag taaggacttt atcccttatt atgagagtga
    19981 tggccaccgt ttttatcact atgtggctca gaatgctagt atcccagtag cttctcatct
    20041 ttctgatatg gaagtaggca agaaatatta ttcggcagat ggcctgcatt ttgatggttt
    20101 taagcttgag aatcccttcc ttttcaaaga tttaacagag gctacaaact acagtgctga
    20161 agaattggat aaggtattta gtttgctaaa cattaacaat agccttttgg agaacaaggg
    20221 cgctactttt aaggaagccg aagaacatta ccatatcaat gccctttatc tccttgccca
    20281 tagtgcccta gaaagtaact ggggaagaag taaaattgcc aaagataaga ataatttctt
    20341 tggcattaca gcctatgata cgacccctta cctttctgcc aagacatttg atgatgtgga
    20401 taagggaatt ttaggtgcaa ccaagtggat taaggaaaat tatatcgata ggggaagaac
    20461 tttccttgga aacaaggctt ctggtatgaa tgtggaatat gcttcagacc cttattgggg
    20521 cgaaaaaatt gctagtgtga tgatgaaaat caatgagaaa ctaggtggca aagattagta
    20581 ctataagtga atatgatttg agtgaatagt aagttaaaaa tcctgatttc aagtaaaatc
    20641 aggatttttt catggatgca atttttttgg agtctggtgt gacgcggagg gtcttttgtc
    20701 ctgtgtaagt gacaaagccg ggttttccac cagttggttt attgagtttt ttgacttcaa
    20761 tcatatctac ctgcaccaga ttcgacaggc gcccttgaga gaagtaggca gctaactctg
    20821 ctgcgtctgt cttgactgca tcagatgggt caagatttcc tgagatgaca acatggcttc
    20881 caggaatgtc cttagcatgg aaccaaagtt cctccttgcg ggccatttta aaggtcaatt
    20941 cctcattttg aagattgttt cgtccgacat agatgatggt tttgccatcg cttgctagat
    21001 attgttctag ttttttgcgt ttctggattt tctcccgttg tcttctgcgg ataaaacctg
    21061 tttgaatcaa ttcttcacgg atttcagcga tttcttccag tccagcttgg ttgaggacgg
    21121 tttctacact ttccagatag agaatagtgg ctttggtttc ttcaatcaaa tcagtcaagt
    21181 atttgacagc ttctttgagt ttctgatacc gtttaaaata gcgttgggca ttctggttgg
    21241 gagtcagagc cttatcaagc gcaatcatga taggttggtt ggtatagtag ttgtctagga
    21301 taacctggtc ttggtcgtta ggcacttggt ggaggaaggt tgtcagcaat tctccttttt
    21361 gacgaaattc ttcagcgttg tctgtcgcca gtaactcttt ttcctgtttt ttgagtttgt
    21421 gtcggttttt ctgaagttca ttttcaacac gacgaatcag ttcactggcc tgctgtttga
    21481 cgcggtcgcg ctcagcctta tccttatagt aggtgtccaa caaatcagaa agatttgcaa
    21541 aaggctctcc cacctgattt gcaaaaggaa ctggactgaa ggaagtctca gtcaagcatg
    21601 gcttgttttc ttgattgaaa aaatttcgga aagcggaaag tttttcacta accagtatcc
    21661 tttccaattc atttgccgta tcgcgtccca gaccttgaaa gaggctttga agattttttg
    21721 ctgttagttc ttgggtttgc aggatttcaa agagcttttc atccttgata gtaaaaggat
    21781 tgagagattc tgtacttggc ggagcgatat aggtcgatcc tggaagtaag gtgcggtagc
    21841 tattttgtga aaaaccgacg tgtttgataa cttcgaggat tttatgactg cttttatcga
    21901 ccagtagaat attactgtgt ttccccataa tttcaataat caaggtagcc tggatatggt
    21961 ctccaatctc gtttttattg gaaactgtaa tttccacaat acggtcattt tccacttgct
    22021 caatcgactc aatcagggcc ccctgcaaat actttctcaa aaccatgata aaggtagaag
    22081 gttgagctgg attttcaaaa gtcgtttggg tcagctgaat gcgtccaaaa actggatggg
    22141 cagaaaggag caggcgatgg ctttggcgat tgctgcggat ttgcaagacc aactcttgtt
    22201 caaaaggctg attgattttc tggatgcgac cattcactaa ttcgcttcgc aattcctcaa
    22261 ctatgtggtg taaaaaaaat ccgtcaaatg acatcgttct ctccttgtga ttgtattcca
    22321 tagtattata tcaaaaaggt agaataaaat catggaaatg tggtataata aagccaagta
    22381 aagagaaaag agaagcacat gtatattgaa atggtagatg aaactggtca agtttcaaaa
    22441 gaaatgttgc aacaaaccca agaaattttg gaatttgcag cccaaaaatt aggaaaagaa
    22501 gacaaggaga tggcagtcac ttttgtgacc aatgagcgta gtcatgaact taatctggag
    22561 taccgtaaca ccgaccgtcc gacagatgtc atcagccttg agtataaacc agaattggaa
    22621 attgcctttg acgaagagga tttgcttgaa aattcagaat tggcagagat gatgtctgag
    22681 tttgatgcct atattgggga attgttcatc tctagcgata aggctcatga gcaggccgaa
    22741 gaatatggtc acagctttga gcgtgagatg ggcttcttgg cagtacacgg ctttttacat
    22801 attaacggct atgatcacta cactccggaa gaagaagcgg agatgttcgg tttacaagaa
    22861 gaaattttga cagcctatgg actcacaaga caataaacga aaatggaaaa atcgtgactt
    22921 gatatccagt ttagaatttg ctttgacagg tatttttact gctatcaagg aagaacgcaa
    22981 tatgcgaaaa cacgcagtga cggctctagt ggtcatcctt gcaggttttg gttttcaggt
    23041 gtcacgaatc gaatggctct ttctcctatt gagcattttc ttggtagtag cctttgagat
    23101 tctcaactct gctattgaaa atgtggtgga tttggccagt cactatcact tttccatgct
    23161 ggctaaaaat gccaaggata tggcggctgg cgcggtatta gtggtttctc tttttgcagc
    23221 cttaacaggc gcattgattt ttctcccacg aatctgggat ttattatttt aaacagtaag
    23281 aggaaattat gacttttaaa tcaggctttg tagccatttt aggacgtccc aatgttggga
    23341 agtcaacttt tttaaatcac gttatggggc aaaagattgc catcatgagt gacaaggcgc
    23401 agacaacgcg caataaaatc atgggaattt acacgactga taaggagcaa attgtcttta
    23461 tcgacacacc agggattcac aaacctaaaa cagctctcgg agatttcatg gttgagtctg
    23521 cctacagtac ccttcgcgaa gtggacactg ttcttttcat ggtgcctgct gatgaagcgc
    23581 gtggtaaggg ggacgatatg attatcgagc gtctcaaggc tgccaagatt cctgtgattt
    23641 tggtggtgaa taaaatcgat aaggttcatc cagaccagct cttgtctcag attgatgact
    23701 tccgtaatca aatggacttt aaggaaattg ttccaatctc agcccttcag ggaaataacg
    23761 tgtctcgtct agtggatatt ttgagtgaaa atctggatga aggtttccaa tatttcccgt
    23821 ctgatcaaat cacagaccat ccagaacgtt tcttggtttc agaaatgctt cgcgagaaag
    23881 tcttgcacct aactcgtgaa gagattccgc attctgtagc agtagttgtt gactctatga
    23941 aacgagacga agagacagac aaggttcaca tccgtgcaac catcatggtc gagcgcgata
    24001 gccaaaaagg gattatcatc ggtaaaggtg gcgctatgct taagaaaatc ggtagcatgg
    24061 cccgtcgtga tatcgaactc atgctaggag acaaggtctt cctagaaacc tgggtcaagg
    24121 tcaagaaaaa ctggcgcgat aaaaagctag atttggctga ctttggctat aatgaaagag
    24181 aatactaagt agaggtaggc tcatgcctgc ttcttgtttt tacagaagga ggacttatgc
    24241 ctgaattacc tgaggttgaa accgtttgtc gtggcttaga aaaattgatt ataggaaaga
    24301 agatttcgag tatagaaatt cgctacccca agatgattaa gacggatttg gaagagtttc
    24361 aaagggaatt gcctagtcag attatcgagt caatgggacg tcgtggaaaa tatttgcttt
    24421 tttatctgac agacaaggtc ttgatttccc atttgcggat ggagggcaag tatttttact
    24481 atccagacca aggacctgaa cgcaagcatg cccatgtttt ctttcatttt gaagatggtg
    24541 gcacgcttgt ttatgaggat gttcgcaagt ttggaaccat ggaactcttg gtgcctgacc
    24601 ttttagacgc ctactttatt tctaaaaaat taggtcctga accaagcgaa caagactttg
    24661 atttacaggt ctttcaatct gcccttgcca agtccaaaaa gcctatcaaa tcccatctcc
    24721 tagaccagac cttggtagct ggacttggca atatctatgt ggatgaggtt ctctggcgag
    24781 ctcagattca tccagctaga ccttcccaga ctttgacagc agaagaagcg actgccattc
    24841 atgaccagac cattgctgtt ttgggccagg ctgttgaaaa aggtggctcc accattcgga
    24901 cttataccaa tgcctttggg gaagatggaa gcatgcagga ctttcatcag gtctatgata
    24961 agactggtca agaatgtgta cgctgtggta ccatcattga gaaaattcaa ctaggcggac
    25021 gtggaaccca cttttgtcca aactgtcaaa ggagggactg atgggaaaaa tcatcggaat
    25081 cactggggga attgcctcag gtaagtcaac tgtgacaaat tttctaagac agcaaggctt
    25141 tcaagcagtg gatgccgacg cagtcgtcca ccaactacag aaacctggtg gtcgtctgtt
    25201 tgaggctcta gtacagcact ttgggcaaga aatcattctt gaaaacggag aactcaatcg
    25261 ccctctccta gctagtctca tcttttcaaa tcctgaagag caaaaatggt ctaatcaaat
    25321 tcaaggggag attatccgtg aggaactggc tactttgaga gaacagttgg ctcagacaga
    25381 agagattttc ttcatggata ttcccctact ttttgagcag gactacagcg attggtttgc
    25441 tgagacttgg ttggtctatg tggaccgaga tgcccaagta gaacgcttaa tgaaaaggga
    25501 ccagttgtcc aaagatgaag ctgagtctcg tctggcagcc cagtggcctt tagaaaaaaa
    25561 gaaagatttg gccagccagg ttcttgataa taatggcaat cagaaccagc ttcttaatca
    25621 agtgcatatc cttcttgagg gaggtaggca agatgacaga gattaactgg aaggataatc
    25681 tgcgtattgc ctggtttggt aattttctga caggagccag tatttctttg gttgtacctt
    25741 ttatgcccat cttcgtggaa aatctaggtg tagggagtca gcaagtcgct ttttatgcag
    25801 gcttagcaat ttctgtctct gctatttccg cggcgctctt ttctcctatt tggggtattc
    25861 ttgctgacaa atacggccga aaacccatga tgattcgggc aggtcttgct atgactatca
    25921 ctatgggagg cttggccttt gtcccaaata tctattggtt aatctttctt cgtttactaa
    25981 acggtgtatt tgcaggtttt gttcctaatg caacggcact gatagccagt caggttccaa
    26041 aggagaaatc aggctctgcc ttaggtactt tgtctacagg cgtagttgca ggtactctaa
    26101 ctggtccctt tattggtggc tttatcgcag aattatttgg cattcgtaca gttttcttac
    26161 tggttggtag ttttctattt ttagctgcta ttttgactat ttgctttatc aaggaagatt
    26221 ttcaaccagt agccaaggaa aaggctattc caacaaagga attatttacc tcggttaaat
    26281 atccctatct tttgctcaat ctctttttaa ccagttttgt catccaattt tcagctcaat
    26341 cgatcggccc tattttggct ctttatgtac gcgacttagg gcagacagag aatcttcttt
    26401 ttgtctctgg tttgattgtg tccagtatgg gcttttccag tatgatgagt gcaggagtca
    26461 tgggcaagct aggtgacaag gtgggcaatc atcgtctctt ggttgtcgcc cagttttatt
    26521 cagtcatcat ctatctcctc tgtgccaatg cctctagccc ccttcaacta ggactctatc
    26581 gtttcctctt tggcttggga accggtgcct tgattcccgg ggttaatgcc ctactcagca
    26641 aaatgactcc caaagccggc atttcgaggg tctttgcctt caatcaggta ttcttttatc
    26701 tgggaggtgt tgttggtccc atggcaggtt ctgcagtagc aggtcaattt ggctaccatg
    26761 ctgtctttta tgcgacaagc ctttgtgttg cctttagttg tctctttaac ctgattcaat
    26821 ttcgaacatt attaaaagta aaggaaatct agtgcgagta aaaattaatc tcaaatgctc
    26881 ctcttgtgac agtatcaatt acctaaccag taaaaattca aaaacccatc cagacaagat
    26941 tgaggtttta aagtattgtc ccaaggaaag aaaagtaacc ctacatcttg aatctaagta
    27001 gattttatgg taaaataata gggattttaa ggagtttgat atgtataacc tattattaac
    27061 cattttatta gtattatctg ttgtgattgt gattgcaatt ttcatgcaac caaccaaaaa
    27121 ccaatccagc aatgtatttg atgccagttc aggtgatttg tttgaacgca gtaaagctcg
    27181 cggttttgaa gctgtaatgc agcgtttgac agggatttta gtctttttct ggctagccat
    27241 tgccttagca ttgacggtat tatcaagtag ataagaaaat aatgggcagg actaggtctt
    27301 tgcctctttt tatttttaaa ggatgtttga gaaggtt
//
LOCUS       DAVIME010000027        24756 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVIME010000027 DAVIME010000000
VERSION     DAVIME010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.027"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            174..885
                     /locus_tag="VV588_001259"
                     /pseudo
     CDS             174..885
                     /locus_tag="VV588_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            897..1646
                     /locus_tag="VV588_001260"
     CDS             897..1646
                     /locus_tag="VV588_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU7083601.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
     gene            1659..2830
                     /locus_tag="VV588_001261"
                     /pseudo
     CDS             1659..2830
                     /locus_tag="VV588_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            3225..4088
                     /locus_tag="VV588_001262"
     CDS             3225..4088
                     /locus_tag="VV588_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU7083602.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYVPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            4257..4469
                     /locus_tag="VV588_001263"
     CDS             4257..4469
                     /locus_tag="VV588_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083603.1"
                     /translation="MRFSKISQFPCYTVLVKHLKQILGRRSGLQKNNQRRKEMHNLME
                     LELLPEEPVITVSREVCKWTCSFTAL"
     gene            4554..7067
                     /locus_tag="VV588_001264"
     CDS             4554..7067
                     /locus_tag="VV588_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU7083604.1"
                     /translation="MDRLQTMLNKIQVDTYHKNGWLFVKYSNNKLTQGWKLHVSSQLK
                     DACNIFYIVAQELEKERCNYKVLDCLDELKKLNSPREVSPTANKFITIYPSSRKQAKR
                     IILNLKEKLEKYKAPRILSDFQCGEYSPIHYRYGAFKAIKNYNFSENKIVYMMKNSRG
                     ELVEDLRLSYPYLPEGVKDLFTDMEKNKLFKPSPEIPENHPLNHYNIECILKKSNRGN
                     VYRAIEKSSNQKVIIKHARPYVYSWNDGFSAIDELKSEAANLKVFQDKSYTTDLIEEF
                     YVNEDYFVVQKFIPGYNFFDLKNIDIEKNVIINNIIDIINDIHAEGYLAVDISPTNFI
                     LDDFGRVRLIDLENFTNKNNTVRRAATKFMINTDCPSKICTIQQDYFALAMLSFAIMR
                     EHVLIFEGEDVLLNITALDKIKFCMYSEKEIGNITKSQFNWLMYLLNLSEQEKLDRFE
                     KMKYINDFEDKNIEFHLKKVDSSFNLQIENETLINYLLSLNMNRESRILNSNEFGEFV
                     SPISFQHGLSGYLFYLSHMRDISENGRIIEWIISEGNQNKGNVYLNGCSILFGSSGYL
                     WVLLEFYKKITSNNPSRELIIDKIRDIYKDLISSYQKVEVFDFALGKSGILLSLMKYC
                     INFNDVDSMEFIREKIEELYLYFVDEIRNVNSLKECNFAHGLAGIAYVILIYNSEFEF
                     KVAYENSIKVFNNLLENLLENEYSRLNATPTNLELSWCEGTSGILLYFELLYDKRYSN
                     IISRFQQLAFKFNLIQSSCYCHGLSSLLQTLNYQDKLNLRENVIEILLSRSKRDKNGI
                     LVFECEESSDTLFDFGIGNLGIYWSILGERFPFELKKEL"
     gene            7067..8293
                     /locus_tag="VV588_001265"
     CDS             7067..8293
                     /locus_tag="VV588_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU7083605.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            8741..9397
                     /locus_tag="VV588_001266"
     CDS             8741..9397
                     /locus_tag="VV588_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU7083606.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSIWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            9387..9710
                     /locus_tag="VV588_001267"
     CDS             9387..9710
                     /locus_tag="VV588_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU7083607.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            9814..10644
                     /locus_tag="VV588_001268"
     CDS             9814..10644
                     /locus_tag="VV588_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7083608.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            10798..11652
                     /locus_tag="VV588_001269"
     CDS             10798..11652
                     /locus_tag="VV588_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU7083609.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            11752..13125
                     /locus_tag="VV588_001270"
     CDS             11752..13125
                     /locus_tag="VV588_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU7083610.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESCTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            13118..14179
                     /locus_tag="VV588_001271"
     CDS             13118..14179
                     /locus_tag="VV588_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU7083611.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            14181..14873
                     /locus_tag="VV588_001272"
     CDS             14181..14873
                     /locus_tag="VV588_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083612.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(14903..15472)
                     /locus_tag="VV588_001273"
     CDS             complement(14903..15472)
                     /locus_tag="VV588_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU7083613.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            15607..16221
                     /locus_tag="VV588_001274"
     CDS             15607..16221
                     /locus_tag="VV588_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU7083614.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            16223..17869
                     /locus_tag="VV588_001275"
     CDS             16223..17869
                     /locus_tag="VV588_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU7083615.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQASYSDQRQ
                     SIGIINVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            17881..19167
                     /locus_tag="VV588_001276"
     CDS             17881..19167
                     /locus_tag="VV588_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083616.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATVSHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            19228..19761
                     /locus_tag="VV588_001277"
     CDS             19228..19761
                     /locus_tag="VV588_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083617.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            19839..20309
                     /gene="nrdI"
                     /locus_tag="VV588_001278"
     CDS             19839..20309
                     /gene="nrdI"
                     /locus_tag="VV588_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU7083618.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(20602..21864)
                     /locus_tag="VV588_001279"
     CDS             complement(20602..21864)
                     /locus_tag="VV588_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU7083619.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(22174..22632)
                     /locus_tag="VV588_001280"
     CDS             complement(22174..22632)
                     /locus_tag="VV588_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU7083620.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(22629..23069)
                     /locus_tag="VV588_001281"
     CDS             complement(22629..23069)
                     /locus_tag="VV588_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083621.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            23502..24368
                     /locus_tag="VV588_001282"
     CDS             23502..24368
                     /locus_tag="VV588_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7083622.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
BASE COUNT         7772 a         4094 c         5204 g         7686 t
ORIGIN      
        1 tgtttttttc tacacttata ccataaaggg gaaactcttt tttgtctagt aaaaaacacc
       61 cattgggtga aaaaagaaac catccaggat ctaagctaag gcaaggattc tggatggttt
      121 ttagatttgg ggtgaataat tggggagaat attttcccga tatagtatgg agattggaag
      181 gaagtctctt tgaatgtggt gtcatactgc agtactattt aggcaggttg ttgttccaaa
      241 aagggaacac aagtattctt tgtggcgagt cagcggatga aataatgact tttaagtatc
      301 attctgtgaa ctacaatcaa ttttgtaatg ataaacagaa gtcagtatat tttagttatt
      361 ccgactatcc attttatgtt acaaattcaa ttgttttaaa gaaaaatagc ctacttttgc
      421 atagttttgg cattcatcct agatatccat ataaaatgtc tgagattgtt gaaatgtcta
      481 aaaaaatatc agatttaaac gataaaaaag aatttcacaa aaagaactgt gagttgaggt
      541 ttcaagatag tgttcttgat aacataaata gtgtcccggg tacaactcat ttatttagtt
      601 gtttaaatat tcaaacatta gtaaaaatta ttttatatat ttttcgatac aacagttgta
      661 tcgaaaatat ttaattttag agataaagag cttatctttt ttaataagat tgtaaatggg
      721 ctgatacaaa atattgagga gaatttagag gatgatattg aaaggatatt gaaatattta
      781 tatatatgtt tatttaacga aatattcatt attaagaata aggtgaattt ttttgatgat
      841 gtggaattta atcagacact tagtgagttt ttagataaat tgtagaggga atggttatga
      901 gtaacaatac taagtatatc tttttatctc cacatttaga tgacgcaatt ttttcctgta
      961 gtgattatat ttcaaaatta acttcagaag gagaaattgt acttgttatt actatatttt
     1021 ctggttaccc tttgagccaa cagctacagc cctctgctaa gcaatttcat aagttgtgta
     1081 accttgggaa atatccgatt gaagaaagga agaaagaaga caggttagct tgtgaacgtc
     1141 tacaatgtga ttttagacac ttatcgtact atgaatgtct ctataggaaa gatagaaatg
     1201 gcaattttct ataccgtcat atctatagtg aattaaaaaa tgaggacaca ttaaagaatg
     1261 atatcataaa agagctgtta atgcatttag acgataaatg tgtcgtatat tgtccgcttt
     1321 cacttggtga ccatgttgat catgtttttg tgaatagtat tggaagggcg cttgaattta
     1381 tgcgttataa agtaatatat tatgaggatt tcccatatgt aagtgatagt agtatggtta
     1441 gttatatggg aaaaactaaa gaattaaaaa tgtatcaaga ggaacttgat gaaaaacatt
     1501 atattgatag aatatcatca atattgtgct ataaatctca gattttgata atctggaaat
     1561 cagttgaaaa acttttaaac aatattaaag agttgtattt aaggaatggg gcagcttatt
     1621 ctattatatt ttggattaag aaataaggaa gtagttttat gaatatagca gtaattggtt
     1681 tggggcatgt tgggctggcc tacgcgttac tatttgcatc taaatataaa gttgttgcat
     1741 atgatataga ttctgtaaaa ataaataatt taaaaaaggg cattcttcca tctaaaaatg
     1801 aagagcttat gaagtttttt tgcgagaata acttaaatat tacttttttt gatacatttt
     1861 ctgaaattaa aaataatatt gattattata ttattgcgct tccgacagat tatgatgaga
     1921 aaattggtag ttttaataca tatgaaatcg aacaaacggt atcgaagatt ctgagggtaa
     1981 aacctaatgg aaagattatt ttaaagtcaa cagttccgat cggcttttca aacaaattaa
     2041 aaaggctgtt tgatacaaaa aatatcattt ttgtccctga atttttgaga gaaggttgtt
     2101 ctatatatga taatttatat ccaagtcgca tagttgttgg agatgagaca gttgaaggaa
     2161 gaaaaattgc agagttgttc ctttcgatta gtactcatag tactgccaat attaaaaatg
     2221 ttatgttagt ttctcctact gaagcagaag caattaagct tttttctaac acattcttag
     2281 ctctccgtgt tgctttttta atgaactaga ttcttttgct gagaggagaa gtttaaatgc
     2341 tgaagttgta ataaaaggtg tttgtttaga tccaagaatt ggaaattttt ataataatcc
     2401 ttcttttgga tttggaggat attgtcttcc caaagatact aaacaattaa aaaaagaatt
     2461 tatagaaata aatgccccag tgatagaagc gattgatatt tcaaacacaa atagaaaaca
     2521 gttcatagtt aaacaaatat tggaacgaaa gccaaagata gtaggaatat ataaattggg
     2581 gatgaaatat aattcagata attacaaaga gtcagctatt ttaagtataa ttaatgaact
     2641 attgattgtc ggtataaaaa ttttagtata tgaaccaaat ttaaacgtta gtatagataa
     2701 cgtaattttt gaaaagaatt ttgaactatt tacaaaacaa agtgatctaa ttgttgcaaa
     2761 tagatgggat aggggccttg aagcttataa agataaagtt tacacaaggg ggatctggat
     2821 aagagattaa ctattgatat taaaaaggca ataatttata aaatttgtac aaaaaaatgt
     2881 taaattttca cattttcata gtatactgtt taatagaaag taggttcttt gtaaccgctc
     2941 cattataaaa tcctttcact cttccggtat actattagga aaaacataac tggaggatat
     3001 tttgagctca cacctcatcg ttccagtggc tgttccccaa gctcgtgtac tgcccaaaaa
     3061 agttagacat tctatttaga acgaggattg agttctgtat tgtacaaggc tcggtccttt
     3121 tagagtcagc ttaaggctgg cttttttgcc ctcttaaata tcagaatatt ttgacaaatg
     3181 attgtaaata atgatataat atgcaaaagc taggaggtgg tcagatgatt gagagaatgg
     3241 aattgggaga attttacaag gaattgcgct tggcgagaaa acttaagcag tcagatgtgg
     3301 cctgtgaggg tctaacagct tctcagttgt ccaagtttga actaggacag tctatgttat
     3361 ctgcagataa gctcatatta gccatccaag ggatcaatat gaattttgat gagtttgggc
     3421 acaagctcaa caactatcaa gaatctccac atatgcgaat cggtcgaaag gttgtggatc
     3481 gctttgccca tcaggatata gctgctttag agcagctatt ggaggaagtc gatcaagaac
     3541 agatggcgca gacctatcgt cgtttgaatg ccattgtgat taaaaatgca ctccattcct
     3601 tagataaaag ctacccgcta acagaggagg atagcgagtt tttgactacc tacctctacg
     3661 ctattgagtc ttggacctgg tttgaactct atcttttttg caatactatg cccttcttga
     3721 gcaatcaaga tctgatcttt ttatcaacct ccttactcga aaaatccaag gaatttaaag
     3781 agttagtaca caatcgatgg tatatgaaaa gtggttatct taatatcatc tcagaactta
     3841 tggagcgcaa gctattttct tatgttccaa tctttgaagc tgagctggag cgcatgctcc
     3901 gtccatacga tgtttttgaa aaagtattgt ggcagttttt aaagaaaatg cagatttttc
     3961 ttcaaaccaa aggaagcaat caaaaagaga ttgaacactt tatccaatct ctgcaagtat
     4021 tagaaaatcc acaattgaca gccctttttg aattgcgttt gcagcaatac aaagagctta
     4081 tcgattagtt agaaatggga aaaagataat aatatcagca acgatcgtca ataatgttaa
     4141 aacttgtttc ttcatattac ttccctcctc attagtaata actttattat accagggaaa
     4201 taatcaaatc taccaaaatc gcaaatctga aatttctata agaaaaaata tcaaatatgc
     4261 gattttctaa aataagccaa tttccgtgtt atactgtcct tgtaaaacat ttgaagcaaa
     4321 tcctaggtcg cagaagtggt ttacaaaaaa ataatcaaag gagaaaagaa atgcataatc
     4381 taatggaact tgaattgtta cctgaagagc cagtaattac tgtatcacgg gaagtttgta
     4441 agtggacttg ctcatttact gctctttaag aataactggt taaaattaag gatagttgat
     4501 tactaattaa ctatccttaa tttcatttca gagataatgt atttattata tttatggata
     4561 gattacaaac aatgctgaat aaaatacaag ttgatactta ccataaaaat ggatggttat
     4621 ttgtgaagta tagtaacaat aaacttacac agggatggaa acttcatgta agcagtcaac
     4681 taaaagacgc ttgtaatatt ttttatattg ttgcacaaga gctggaaaag gaaagatgta
     4741 actacaaagt tctagattgt ttggatgagt taaaaaaatt aaattctcct agggaagttt
     4801 ctcctactgc aaataagttt atcactatat atccgtctag taggaagcag gccaaacgaa
     4861 taatattaaa tctaaaagaa aagttagaaa aatataaagc tccaaggatt ttatcagatt
     4921 ttcaatgtgg tgagtattct ccaatacatt atagatatgg tgcgtttaaa gcaattaaaa
     4981 attacaattt ttctgaaaat aaaattgtct acatgatgaa aaatagtaga ggagaattag
     5041 tagaagatct gagattaagt tatccatatt tgccagaagg ggttaaggat ttatttactg
     5101 atatggaaaa aaataaatta tttaaaccct ccccggaaat cccagagaat caccctttaa
     5161 atcactataa tatcgagtgt attctaaaaa aatccaatag aggaaatgtt tacagagcta
     5221 tagaaaaaag tagtaatcag aaagtgataa taaaacacgc acggccatat gtttatagtt
     5281 ggaatgatgg tttctctgca attgatgaat taaagagtga agcagcaaat ttaaaagtat
     5341 ttcaggataa gtcctataca acagatttaa ttgaagagtt ttatgtcaat gaagattact
     5401 tcgtagtaca gaagtttata ccaggatata atttttttga tttaaaaaat attgatatcg
     5461 aaaaaaatgt aatcattaat aatataattg atattattaa tgatattcat gctgagggat
     5521 atttagcagt ggatatttct ccaacaaact ttatattgga tgattttggt cgtgttaggt
     5581 taatagactt agaaaatttt acaaacaaaa acaatactgt tagaagagct gctacaaaat
     5641 tcatgataaa tactgattgt ccctcaaaaa tctgtaccat tcaacaggat tattttgcac
     5701 ttgcaatgtt gagttttgct attatgcgcg agcatgtttt aatatttgaa ggagaggacg
     5761 tcttattaaa tataactgct ttagataaaa tcaagttttg tatgtatagc gagaaagaaa
     5821 ttgggaacat aactaaatcg caatttaatt ggttgatgta tttattgaat ttaagtgaac
     5881 aagagaagtt agaccgattc gagaagatga agtatataaa cgattttgaa gataaaaata
     5941 tagaatttca tttaaagaaa gttgattcct cattcaatct tcaaattgaa aatgaaacgc
     6001 ttattaacta tcttctttcg ttaaatatga atagagaaag caggatacta aattcaaatg
     6061 aatttggaga atttgttagt ccaatatcgt ttcaacatgg cttatcagga tatttgtttt
     6121 atttatcaca tatgagagac atttctgaga atggtagaat tatcgagtgg attatctctg
     6181 aaggaaatca aaataaagga aatgtgtatc taaatggttg ttcaatttta tttggttctt
     6241 ccggatatct ttgggtatta ttagagttct ataaaaaaat taccagcaac aatccaagta
     6301 gagaattgat catagataaa attagagata tttataaaga cttgataagt agttatcaaa
     6361 aagttgaagt atttgacttt gctttaggaa agtcaggtat tttattgagt cttatgaaat
     6421 actgtataaa tttcaatgat gtcgatagta tggaatttat tagagaaaaa atagaggagt
     6481 tatatttata ttttgtagat gagatacgaa atgttaatag tttaaaagaa tgtaattttg
     6541 cacatggtct agctggaatt gcatacgtaa ttttaattta taattcggaa tttgaattca
     6601 aggtagctta cgaaaatagt attaaggtat tcaataatct gttagaaaat ttgttagaaa
     6661 atgaatatag tagactaaat gcaactccta caaatttaga actatcgtgg tgcgaaggaa
     6721 cttcaggaat cttactttat tttgagttat tatatgacaa aaggtattca aacataattt
     6781 caaggtttca acaacttgct ttcaaattca atcttatcca gtcaagttgt tattgtcatg
     6841 gcttatccag tttgttgcaa actctaaact atcaggataa attaaattta cgtgagaatg
     6901 tgattgagat tttattaagt agatccaaaa gagataaaaa tggtattttg gtatttgaat
     6961 gtgaagaaag ttcagataca ttatttgatt ttggtatcgg aaatctaggg atttattggt
     7021 ctatccttgg ggaaagattc ccatttgaac ttaagaagga gttgtgatga aagtatttct
     7081 tcaaaataga gattttaggc aattaactat caaccagtgg atttcaacgc ttggggatac
     7141 gattttttat ctggccttcc tgaattatgt ggcagatgca tcttttgccc ctttggcgat
     7201 tttactcatc acgatttcag aaaccctgcc ccaagttcta caaatctttc tgggagtttt
     7261 ggcggatttt caacatcatc gtgtcttgaa atacacagtc attagttttg caaaattttt
     7321 gctttactct atagtgtctt tatcactttc agggcagtcc ttttccttgt tattagtagc
     7381 atttatttgt ctgattaacc tcttgtctga cacgttgagt tatttttcag gcgccatgct
     7441 cactccgatt ttcattagaa ttattgggca agaccatctg gcagaagcta ttggatttaa
     7501 acagtcaact gttagtttag tgaaaacaat cagtaatatt ctaggaggag tcttattagg
     7561 tattctatcc atccagttta tttccttgct gaacgctctt acctttttaa tcgcattttt
     7621 aggtatcctc ttcataaaaa ctgacctctt gaaagtagaa aaaacgatta actatcaaga
     7681 aggactctct gtaaaatcct tttgccagca tttgctccaa tcatcgaaat tgatatggaa
     7741 tatgaataag gtgctcttgg ttttgtttat tatctctact agtcaagcag tgataaatgt
     7801 tacagttcct gtctctactc tatttttgag gaatcaaccc tttttgaatt tacaaacagg
     7861 tcaatctctt gccttgctat ccacttttga actgtcagcc ctgattgtcg gaagccttgt
     7921 aagtggctat ctgcaacata ccatttccat aaaaacagct ctctatgcct cacttgtcac
     7981 ccagttgctt cttctagtag gatttgccac agttcgtttt gactggattc tcatctttag
     8041 taccttggat gcctttttcg caggtgttct ctctcctaga ttgcaagaac tcgtttttaa
     8101 acaaatacct gaggagtcaa tgggagcagt tcaatcctct atcggtgcca ttacggttgt
     8161 tttacctagc ttatttacaa tagctttggt aaccattgct actagctttg gaactctggc
     8221 agttagcttt gttttattgc tatttcttct agttgccttt gttatgcttc tgaatattcg
     8281 tgaaagtatt tagtggagaa tttctataat atatgtttga gactggattg ccagcctttt
     8341 tatgatggtc aaaatcaaca gacttttttc tcttttctga atgtgttata atagactgaa
     8401 tctaaaatag tacgaaacaa ttgctaaaac atttatttat agaaattaat tttactttcc
     8461 caatcgattt gttctcatct tatttcaatc tgctatataa tagtccatgc tgtggctgga
     8521 ttcttttcag cctacttata ctcttcgaaa ctctcttcaa accacgtcag cttcaccttg
     8581 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag
     8641 ctgactacgt cagttctatc tgcttttcat tgagtactat taagacaata tgaggagaaa
     8701 gatgaaagaa aaaggatttt aggagggggc gcaggcagcc atgccaacgg ctcttggcta
     8761 tgtcagtatc ggcctggcct gtgggactat cggtgcgccc tatgtgacac ctgttgagat
     8821 gggcttgatg agtctctttg tttatgctgg gagtgcccag tttgccatgt tggcactgat
     8881 tgtggttcaa gctcctgtgg cagctattgc tatgacggtt tttctaatca acttgcgtct
     8941 ctttttgttg agtttacacg catcgactta tttccgtcat accagtattt ggtacaatat
     9001 cggtatgtct agtatcttga cagatgagac ctatggcgtt ttgatgggtg aattggccca
     9061 tacagacaag gtaaatccta tgtggatgca cggaaacaat cttaacagct atgtggcttg
     9121 gtttgtgggg acagtagtcg gaacggctct gggtggcctg ctaccaaatc cagaaatctt
     9181 tggcttggat tttgccctgg ttgggatgtt tattggtatt tttgcttcgc aatttcagat
     9241 tatgcaaaga cggattcctg tccgcaatct gctcattatc ctagcagttg ttgcggtgtc
     9301 cttctttttg ctcttgacag tggtgtctca gtcactagct gttctgtttg cgacgctact
     9361 tggttgtagc atgggggtgg ttttagatgg tcagtaagta tcttttatta gcagttattt
     9421 tctctggctt ggtgacttgg attctccgta tgattccctt catcttagtc aagtataagg
     9481 gcttgcctgc aatcgttgag cgttttttga agttcttgcc cgtttccatt atctttgcct
     9541 tgattctttc aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag
     9601 acttcttagc cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa
     9661 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
     9721 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
     9781 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
     9841 cttgctgccc taggacttgt tgctgcaggt gtgcttgcgg cttgctcagg gggtgctaag
     9901 aaagaaggag aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaagg
     9961 ccatttatct atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct
    10021 atctttaaag attctgacaa atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc
    10081 tttgctggtc ttgacgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
    10141 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc
    10201 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
    10261 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaatgctga acacacggac
    10321 aacccaacta tccttaacta tactaaggca gacttccaac aaatcatggt acgtttgagc
    10381 gatggacaat ttgactacaa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
    10441 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
    10501 ccacttcttg ctcaaggtca agatgagttg aaatcatttg tagacaaacg catcaaagaa
    10561 ctttataaag atggaactct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
    10621 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta aggtgggtgg
    10681 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
    10741 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
    10801 aaaatcaaaa aatggcttgg cctagcagcc cttgctacag tcgcaggttt ggctcttgca
    10861 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt
    10921 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
    10981 ggaattacct tggaatttac agagttcaca gactattcac aaccaaacaa agcaactgct
    11041 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaacaa ctggaacaaa
    11101 gaaaacggaa aagaccttgt agcgattgga gatacttaca tctctccaat ccgcctttac
    11161 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
    11221 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
    11281 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
    11341 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
    11401 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
    11461 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
    11521 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
    11581 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaaa catcagacgg tttggatcaa
    11641 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
    11701 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatggttttt
    11761 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagtcca acattatttt
    11821 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
    11881 gaagtcgcaa attatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
    11941 gagagctgta cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
    12001 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
    12061 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
    12121 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
    12181 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
    12241 ctagataagt atttggaaaa gcatgcagac aaactccgtg gggcggattt gttggtctgg
    12301 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taaggggatt
    12361 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
    12421 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
    12481 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
    12541 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
    12601 gagttgcctc tcttacagga ggatcggatg gcctttctaa aacgtttctt tttcgagcca
    12661 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
    12721 cctgcagaag ccagtgccaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
    12781 gttctggaaa aaattcggaa acagctagac aaaaatggct ttgataaggt agaattatac
    12841 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
    12901 atcgagttgg ccaagaaatt ctatccacag ggcgtttcag tcttgccgac gacagcgggg
    12961 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc attcggtcta
    13021 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
    13081 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
    13141 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc atcacagcgg ttaaggatgt
    13201 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcagggaa
    13261 atcaaccctt gtacgggtga ttaatctctt gcaaaaacca tctgcaggga aaattaccat
    13321 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
    13381 acgtcaagat atcggaatga ttttccagca ttttaacctg atgagccaaa agacagcaga
    13441 ggagaatgta gcctttgccc ttaaacactc tgaactcagc aaggaagaaa agaaggctaa
    13501 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
    13561 actatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
    13621 aatcttgatt tcagacgagt caacttctgc ccttgatccg aagacaacca agcagatttt
    13681 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
    13741 aatgcagatt gtcaaagaca ttgccaaccg tgtggcggtt atgcaggatg ggcatttgat
    13801 tgaagagggt agtgtgcttg aaatcttctc agaccctaaa caacctttga ctcaagactt
    13861 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
    13921 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
    13981 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
    14041 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggtct tgtcaggtga
    14101 aaaagcagcg ttggcaggtg cccaagaagc tattcgtcaa gcaggcgtac agttaaaagt
    14161 attgaaggga ggacagtaag atggaatcat tgattcaaac ctatttgcca aatgtctata
    14221 agatgggttg gtctggtcag gcaggctggg gaacagctat ctacctaacc ctctatatga
    14281 cagttctttc ctttatcatc ggaggcttct tggggctagt ggcaggtctt ttccttgtct
    14341 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
    14401 cctcaatttt tcgtgcggtt ccctttatca tcctcttggc aatcttgtca ccactttctc
    14461 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
    14521 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtta
    14581 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
    14641 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
    14701 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
    14761 ttaaccgcta caatcacgat gtgaccatct tggcaaccat tattatcatt ttgattatct
    14821 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
    14881 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
    14941 caatcaaagc acccactagg gctccgatga caatacttgc gataaataga aggacagtcc
    15001 cagggtttgg agcgaccatg atacggtcga tatattcttg ggattttcct cttgccagaa
    15061 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
    15121 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
    15181 ctacttcatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
    15241 tagttcccaa gaaaaagaag gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
    15301 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
    15361 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
    15421 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
    15481 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
    15541 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
    15601 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
    15661 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
    15721 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
    15781 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
    15841 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
    15901 cagaccattg ttcatttgat tgcgaccctt ttgaatgtcc tagtagttgc cctgatcttt
    15961 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
    16021 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
    16081 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
    16141 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
    16201 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
    16261 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
    16321 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
    16381 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
    16441 agctcgtatc gagggaatct ataaatactt tagccttagc atgccagact atttttactg
    16501 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
    16561 cctctatgtt cgaaatgatt ttgtaactgg ggtggccatt gcttttcaag attacaagga
    16621 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
    16681 accagcagga aatagttttg ccattccagt gtcagatcca gtgtcagatc aagacttagg
    16741 agtgatttac atctccttgg atcctgctgt tctataccat gccattgata atactagagg
    16801 tcatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
    16861 tgagacagtt gataaggaga gtgaaaattg gctagttggc ttaacttctc atggttatca
    16921 ggttcaggtg gcagttccca aaaactttgt tttacaagga acggtgacca gctctgcttt
    16981 gattgtgggc ttgagccttc tctttattgt cattctttat ctgactttga ggcagacctt
    17041 tgctaattat caaaagcagg tagtggattt ggtggattcc atccaagcta ttgcccaagg
    17101 acaagaaggt cttcgcattg atacgcttga aaaggatcag gaattgctcc taatcgcgga
    17161 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
    17221 gcttagtcaa aaagatgcca atatgcgagc cttgcaggcg caaatcaatc ctcattttat
    17281 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
    17341 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
    17401 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
    17461 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
    17521 caagtttacc ttgcaaccgc tggtagaaaa ctatttcgcg catggtgttg accacaggcg
    17581 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
    17641 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
    17701 tcagaaatat tttgaacacc aagccagcta cagtgatcaa aggcagtcta tcggaattat
    17761 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta cgatagagtc
    17821 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
    17881 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
    17941 attccctttg ataagtggga tatggaggtc gtcgcaacag tcagtcatgc cgatgaagct
    18001 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
    18061 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
    18121 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
    18181 gactatttgg tcaagcctgt tgataaggta gagctgggaa atctgctgga gaagattgca
    18241 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
    18301 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
    18361 caaggttcct tcgccattcc ctactatgtc ttgggccaag actggcagat tttcatttct
    18421 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacacttt
    18481 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag
    18541 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
    18601 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcgt
    18661 gttccgatta ctaaacagct ttttattcag tttgtcatgg atgttttcca tttatttgaa
    18721 catctcaaag ctgatgacct gacagacatc gtcaaaacca ttcatgctat tcaatccttc
    18781 gatgaattgg ttccttatat caaggaaact ctgagcagct ttttcggtca ataccgtatg
    18841 aatgaaaatg tggtcagtgt gctggaagtc attggtcgtg attaccaaaa agagctttcc
    18901 ctcaaggata tcagtaaggc tctctttatc aatcctgtct atctagggca gttgattaag
    18961 cgtgaaaccg attcgacttt tgcagagtta ctaaacaaac aacgtattaa ggctgcccaa
    19021 caacttttgc tttcaactag tgacagcatc gaagatattt gttatgctgt tggttacagt
    19081 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    19141 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    19201 taaatattat tattaggagg ttctatcatg aaaaagaaac caatttatct atgggtcttg
    19261 ctaatcttgt ctgcccttat ttcagttccg tctctgtttg gaattgtgag tcccttgcct
    19321 agtaaagaag cccttcgtac tgctcagaaa caagttgcag gggtcaatgc tcagcaatta
    19381 gaagaccagc ttaattatac ctatagagta gcagaagcat ctcattctat ttttaatgtt
    19441 gctttgattg tgctatctac tattttagtg gtcgtagcga ttgtcttcct tgttcgtaaa
    19501 aatttgcaat atgcaaacta tacttacgtt ggctatgttt tgttagctat tattggttcg
    19561 atttatggct atgttggttt acaagacgct gtgcagttgg ttcaagatga gagcatgcgt
    19621 ttgacagtga gtattggttc aaaagctgtt agcattttct atatcgtcat caatgttctc
    19681 ttcctagccc ttgtcttcta taagatgtgg cgacaacaga aagccttggc agaagaagag
    19741 gaaacagaag agcttgccta agtattgaca aaaaagaact atcaagatac aatcttggta
    19801 gttgtttttt gattatagat aaaatcatgg aggtacatat gaagacaatt tctttagttt
    19861 atattagttt gagtggcaac actgaaagtt ttgtgacgcg cttgaaagac tatctcttgt
    19921 cccagtacaa agggattgag gttcaaaaga ttcatatcaa ggatttggtc aaggaaggca
    19981 aaaatttcta tgaaatggac catccctatg tcgctttttt gccgacctat ctcgaaggtg
    20041 ggaatggcgt ggataacgga gatgttgaga ttttgacgac accggtggga gattttattg
    20101 cctatggtaa caatgctagt aagtgttttg gtgtggttgg gtcaggaaat cgtaacttta
    20161 ataaccaata ctgcctaaca gccaagcaat acagtcaacg ctttggcttc cctgtattgg
    20221 ctgactttga aatgcgaggc atgctggaag atatcaaaca tgtcgcagct attatcgcag
    20281 atttgtatga gttggaaaag gagaattaat actcaatgaa aatcaaagag caaactagga
    20341 agctagtcgc aggttgctca aagcacagct ttgaggttgc agatagagct gacgtggttt
    20401 gaagagattc tcgaatagta taaagttctt ataagaggtg gttgaagttg ttcaactgtt
    20461 ttttgagtat aaacagtttt taagaacgta aaaaagcata agttcaggtc ttcaaaacct
    20521 tgttcttatg ctttttatca tagaaatatt tgctgaattt tctcttgaaa tgaaacctta
    20581 tcttcatctc gcgcttgtcc cttaccctgc ttttccgatt gcgagtgcgt agataaagaa
    20641 gatggcgaag ccaaagagga aaatcaatcc cgcaatggca aggtgtttga gccaagaagg
    20701 aagatttttg ttttcacgcg ttaccaaggc gtaattcaaa agagcaaaga aaggtgttgt
    20761 caggaaagaa ccaatcatgg caaagcggag catggttgaa acctgaccag cgaagaactt
    20821 gataatgacg ataccgatga tagcagtgat ggtcatccag atgttcaaag atttacgatt
    20881 gtcctctttt tgactgatta gcagtcggag agattcctga ttaacgcgag aatagccatc
    20941 gataacagtt ataactgttc caaagataca gaggaaggca ataaaggtaa tcaagtaacg
    21001 ggaccattcg ccaagaacag aggcatacat gcccacgaat tgagagatgt atttggctga
    21061 agcagcttca accgcctgcc ctgtaggata ctgaatcagt gctcccagtg ccacaaagaa
    21121 gacggctagg atagctgttc caatataacc agtgttaaag tcaaacagag cgtcttctgt
    21181 gttaaagttg acggtctttc tcttttcagc tgaccaaagt gaattgatgg ctgaaatttc
    21241 aataggagcc ggcatccatc ctaggaggga gacgatgaag ggcagagctg ccatttgcca
    21301 aggtgtcttc tcgacaaaat cagaactgta ttctggatgc ttgaccgccg caatgataac
    21361 tgcaagaaca gtcgcaatgg ttaaggcaga cataatccat ttgaccatgc cgtctaaaag
    21421 tttgtagcct ccaaagagta gcatagccca aatgattgca acgagaatga gggaccactg
    21481 agtaatgcta agtccaatca ttgggaaggc actggcgatg atagctgagc acagaatggc
    21541 aacaccagcc gtgttgacca tagccgaaaa gacattgagg ataaagaaaa tccagagata
    21601 gagttttcct ttttcggcat aaccttcaac caaagtcttt ccagtatcag ctgtgtattc
    21661 agcaccaaaa cggaaaaatg gatatttaaa gacattggct aagatgacca agagaagtag
    21721 agaccaaccg taagaaccgc cagcttgagt tgaggataca atgtgggaac ctccaacagc
    21781 ggcagttgcc attaggattc caggtcccat tgcttttagc ttgcttgccc aggttgattg
    21841 atttaaggaa atagcttgcg acatgataaa tactcctttt tgaattttca gaataatctg
    21901 tatatgtaat ctatattcta caaaaaattt tggaaaaatg caagagtatt ttgaaaaaag
    21961 atagaaaatt tacaaagaaa atctgaaata actgttatga tatagaggat tgaaactaga
    22021 atagtacacc tctgcttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt
    22081 atcctgttct tatttcattt cactatagta aggtgcagca ggataaagaa aatccgagaa
    22141 gtttctttct cggatttgct tattatgagg ttcctatttt ctatgctcca agagttgatt
    22201 gatgtgatct acttttttag cctctctttt atagagaata gcccagatga tgagatagac
    22261 aatcgcaaac tcgataatga gctggaggta gaaaatccag tggaaaggga accaaccagc
    22321 aagagttgct agtgggacaa agccagccag cataaggaag aaatgagtca gagtggcacg
    22381 aagcatgctc cagtcacggc taaataagcg gttgccaaag ttgaagagca taccgatggt
    22441 tgcccatata agtgtgcagt agagcaagac cagggcaccg tgaacctgat gctgatccat
    22501 cacttggccg atgagagagt agggatttag tggtgcgtag gtatttggtg cataaatgag
    22561 tgaaaagagg atagagagga tgaggccgat aagaacaccg gtagctgcat cgtgaaatac
    22621 ttgttttttc atagttctaa tttctccttg atggttttta gataacggcg tgaagagtag
    22681 gtgaagcttt cgtttttcaa gaaaatttct accagaccgt ttggcgtgag cttgaggtga
    22741 gagatggaat cgatattgat gatttctgat tgggaaattt ggataaaatt ggttggcaag
    22801 agtttaagaa cctgatagag tcgcaaatca atgctgtagg tctgactcgc ggtttctgct
    22861 agaaccttcc gattctcgat atagaagcgc tgaatcttgc caatctcaac tagatagacc
    22921 tgatcatcga tttttccttt gattttttct ctttggtcca gattttctgc gaactcgatg
    22981 actttctgga ctttttcggt ttcttgaggt gcttggacaa tcagcttttc ctcctcgtaa
    23041 gtctcactaa tctgtagttc tactttcata gttttctctc cttttcagtt atacaaggtt
    23101 gtgatcactt cctgtatatc cttattaaac actattttat agcccatggc aaggaacctt
    23161 gtctatgtgg agggattggg ctcctatgtg gtggagcttt tctgttcttt ctgaaatatg
    23221 gtataatagc actaatcaat ttctaggaaa atagatacgg aaaggggctg aaagaactag
    23281 gggaacagtt ggaattagaa agtgataggt atgaaaagtg gcgttgaagc tgaataagtt
    23341 tataaagcgt ttgaatgaag aaatggaaag taaataagtt gacgatgaat tacaaaatag
    23401 attttatcta caatttgtat ctttcaaatc attgatttga attttagatt taatcatgtt
    23461 acaattaaaa ctgaaatcaa atagaagagg aaaatgcaaa cgtgggcaca ctattagcaa
    23521 caagattaaa aaatagacgg aaagaattaa aaatgtctca gcgagaacta gctgaaggta
    23581 tctgtaaaca ggggcaaatc agtcgattag agagcggaga gtttacccct ggagcggatt
    23641 tcctgaatgc ccttgctaag aagttaaaag tcagtatgga ttattttttt gatgagcagg
    23701 ttgtagagaa agttgaggag ttatcagaat ttaagaaatt agcacagaca tttattacaa
    23761 atcgcaatta tgagtctttg aaatatatat atgaattgga gaatgtaaaa gctcaccgcc
    23821 tatctttagc agataaaatc tacatggaat ggataaaatc tctgatagat ttttattttt
    23881 acggacagaa agaagatgcg attgtacgat tagagggggt attatcacag ttaagtgtat
    23941 ctgatttgaa ctatctccaa gtttcaaaca ccctattcaa tttttattat gatattggag
    24001 atttaggtcg tttcaataaa attcgtgaaa aactagagta tcaagtaaat cacctcaatt
    24061 tgagtacaat cgaagagtta gaactatcta ttaagtttaa ctacaacgtt tgtcgttatc
    24121 tatggttaca gaaaaatatt gaagaagcta ttactaaaat tacagctact ataaaacaat
    24181 gtaaggctta cagaacgaat tatcttttgg ctgatttgta cttattgatg ggaaatgtaa
    24241 gtgaaaattt ttcttctaaa agttcggtga aagaatattt tgagacggca tattttctat
    24301 acaaacttga ggagaacatg tcaatgactc tgaaagttga gcattacatt gcagatataa
    24361 cagaataatg aatacggtgt tcaagtgagc atcgtttttc aaacctagtt cagatacaaa
    24421 aaaagtatca aacaaaaaaa aataaaaaaa cattataaaa acaattgaca agctaatttt
    24481 gaagtgataa attaaatgca agaaaacaaa aggagaggta tatgagaagt ttgtttaaga
    24541 aaatagttgc tgtattagtt attggcttaa ttctgttagg aattgcgaga acacctcaag
    24601 ttcataagat ggctagaggg attgatcctg gtcctgcgaa ttttatttag aaatcaattt
    24661 ctactaattg agtactaatt gagtattaat gggtaaaaag attgtatgga taagaaaaat
    24721 ttacttgtat tggttactgg ttcggtaggt gccagt
//
LOCUS       DAVIME010000028        24486 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVIME010000028 DAVIME010000000
VERSION     DAVIME010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24486
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.028"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..2512
                     /locus_tag="VV588_001283"
     CDS             <1..2512
                     /locus_tag="VV588_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU7083623.1"
                     /translation="VYRNGSDFSVIIVNCLLAVVCKKINSSSTKLLPEFSGLDFSLWQ
                     DYIQSTGSIKELWPSQIELGKQGIFSGKSGIVQMPTSSGKTASINLTLRSAFYSNRID
                     NALIVAPFRALCREIYRDINAHFVDENNVIVSEVFDLPEIPQDFSIFNDGKKRVFILT
                     PEKLLFLLRNHQSFIDEIGLCIFDEAHLFDDPSRGTNFELLLSTVKQIFPKGIQKILI
                     SAVIPNSEAINRWFNEDGVIVSNNSIKTTEKRVAFSDLNGSNEQLYFIDPITFEEEFF
                     VPRTVSVSELEQLGKERKQKVFPELTNANDISIYYGTKLINNGGVGIFCGRKDTVNVI
                     LRRFIDLNNRNYDLTDFLKNSDRSEVEKIGNLIGQNLGYDSVEYTCSQLGVFSHHSGI
                     PMGIRIAIEYAFSKSKINNVVCTSTLAQGINLPIKYLIISSVYQAGDAIKVRDFQNLI
                     GRAGRAGKYTEGTIILTEPNIYKSPKNKWKKQNYKALLNPINTEGCQSNILSIIQFKS
                     VVPTDYRFAPIKFDFWNLIKERFDSSVDYRTKINNILSKLKRKNSLYFKDFNSKIDQI
                     DNTLIAIENYIASMYATELETDSLAENTFGYFLGNEEEKEKIKELFILIKSKIITSSV
                     ETEIIAKNSIGLYQSELLKEWVQENKTSILSCEKEEELLGVLTKKIIDFSNNKEMRKL
                     SIENLNYISQLWIKGISYFQILESCTEKSISIEKRGKSKPIDMSDIISICDNGLGYET
                     SMVLNAINNILEKLVGEELDVLTMLIKRLKYGLPLEKEINIYELGFSDRIVVQVIGQE
                     INSVSKNQIRNEIKQKSARLEDKLSDFPSYYTQIINEM"
     gene            2537..3433
                     /locus_tag="VV588_001284"
     CDS             2537..3433
                     /locus_tag="VV588_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU7083624.1"
                     /translation="MTKISFEIQQQIIQCFGLCFHYKDTVVSFMQTSGVPNDLILKWK
                     SEPKFVWAKNVINELNKTENGRLIIRRIATEFYKMKNIPDEVQDRDRGLDALRKLKRL
                     IGDTQQNKVNETLNNSYHRSRQEMKIQLRQQLLQKIEELKTEYYSLFSSDNPQERGYR
                     LEKIVANLFRINDIDYHDSYRNRTNTQQLDGYFRFEGFDYLVEMKWEKNPVNSPKIAS
                     LKQKVDTKLTSTRGLFLSINGFRDEVIQDFSNKDAKILFMDGQELAYILENRISLYEA
                     LKVKIIGASKTGNPNVSIINQE"
     gene            3836..4074
                     /locus_tag="VV588_001285"
                     /pseudo
     CDS             3836..4074
                     /locus_tag="VV588_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            4218..5447
                     /locus_tag="VV588_001286"
     CDS             4218..5447
                     /locus_tag="VV588_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU7083625.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5467..8163
                     /gene="ppc"
                     /locus_tag="VV588_001287"
     CDS             5467..8163
                     /gene="ppc"
                     /locus_tag="VV588_001287"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU7083626.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    8246..8463
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8576..9580
                     /locus_tag="VV588_001288"
     CDS             8576..9580
                     /locus_tag="VV588_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU7083627.1"
                     /translation="MKNKRLIGIIAALAVLVAGNLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSIGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            9649..10515
                     /locus_tag="VV588_001289"
     CDS             9649..10515
                     /locus_tag="VV588_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083628.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10512..11270
                     /locus_tag="VV588_001290"
     CDS             10512..11270
                     /locus_tag="VV588_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083629.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            11360..13120
                     /gene="dnaG"
                     /locus_tag="VV588_001291"
     CDS             11360..13120
                     /gene="dnaG"
                     /locus_tag="VV588_001291"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU7083630.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            13123..14232
                     /gene="rpoD"
                     /locus_tag="VV588_001292"
     CDS             13123..14232
                     /gene="rpoD"
                     /locus_tag="VV588_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU7083631.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            14246..14575
                     /locus_tag="VV588_001293"
     CDS             14246..14575
                     /locus_tag="VV588_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU7083632.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14690..15733
                     /gene="cpoA"
                     /locus_tag="VV588_001294"
     CDS             14690..15733
                     /gene="cpoA"
                     /locus_tag="VV588_001294"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU7083633.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKEIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            15749..17074
                     /locus_tag="VV588_001295"
     CDS             15749..17074
                     /locus_tag="VV588_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU7083634.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFSDVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDVNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            17105..17281
                     /locus_tag="VV588_001296"
     CDS             17105..17281
                     /locus_tag="VV588_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU7083635.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            17340..17474
                     /locus_tag="VV588_001297"
     CDS             17340..17474
                     /locus_tag="VV588_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU7083636.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSSL
                     "
     gene            17538..18848
                     /gene="obgE"
                     /locus_tag="VV588_001298"
     CDS             17538..18848
                     /gene="obgE"
                     /locus_tag="VV588_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU7083637.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18858..19016
                     /locus_tag="VV588_001299"
     CDS             18858..19016
                     /locus_tag="VV588_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083638.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            20171..21430
                     /locus_tag="VV588_001300"
     CDS             20171..21430
                     /locus_tag="VV588_001300"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU7083639.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGVSIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRYLRGTSVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            21446..21997
                     /locus_tag="VV588_001301"
     CDS             21446..21997
                     /locus_tag="VV588_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083640.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            21990..23267
                     /locus_tag="VV588_001302"
     CDS             21990..23267
                     /locus_tag="VV588_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU7083641.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQSLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            23283..24143
                     /locus_tag="VV588_001303"
     CDS             23283..24143
                     /locus_tag="VV588_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU7083642.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         7775 a         4002 c         5341 g         7368 t
ORIGIN      
        1 agtatatagg aatggaagcg atttttctgt aattattgta aattgtctct tagcagttgt
       61 atgtaaaaaa ataaatagtt catcaacgaa attattacct gaattttcag gattagattt
      121 ttctttatgg caggattata tacaatcaac aggaagcata aaggagcttt ggccatctca
      181 aatcgaatta gggaagcaag gaattttttc aggtaaatct ggaatcgttc agatgccaac
      241 aagttcgggt aaaacagcct caatcaatct aactttaaga tcagcatttt attcaaatag
      301 aattgataat gcattgattg ttgcaccttt tagagcatta tgtagagaaa tatatcgaga
      361 tattaatgca catttcgttg atgagaataa tgtgattgtt agtgaagttt ttgatttacc
      421 ggagattcca caggatttct caatttttaa tgatggtaaa aaaagagttt ttatacttac
      481 tccagagaaa ttgttgtttt tattgagaaa tcatcaaagt tttattgatg aaataggact
      541 ttgtatattt gatgaagcac atctttttga tgatccaagt cgtggaacca attttgaatt
      601 actgttgtca acggttaaac aaattttccc aaaaggaata cagaagattt taatatctgc
      661 tgtaatacca aatagtgaag ctataaatcg gtggtttaac gaagatggag taattgtttc
      721 taataattcg attaaaacaa cagagaaaag agttgcgttt agtgatttaa acgggagtaa
      781 tgagcaatta tatttcatag atcctattac atttgaagaa gaattttttg ttccacgtac
      841 tgttagtgtt agtgaattag agcagcttgg aaaagaacgc aaacaaaaag tttttccaga
      901 actgacaaac gcaaatgata taagtattta ttatgggact aagctaatta ataatggtgg
      961 agtaggaatt ttttgtggaa gaaaagacac ggtcaatgtt attttacgaa gatttataga
     1021 cttaaataat agaaattatg atctaactga tttcttaaaa aactcagata ggtctgaagt
     1081 tgaaaaaata ggaaatttaa ttggtcaaaa tttaggatat gatagtgttg aatatacatg
     1141 tagtcagcta ggagtttttt cacatcattc aggtatacct atggggatac gcattgctat
     1201 agagtatgct ttttcaaaaa gtaaaataaa taatgtagta tgtacttcaa ccttagcaca
     1261 aggtataaac ttacctatta aatacttgat tatctcaagt gtgtatcaag caggagatgc
     1321 aataaaagtt cgtgattttc agaatttgat aggtagagca ggaagggctg gaaaatatac
     1381 agaaggaaca ataattttaa cagagcccaa tatttataaa tcaccaaaaa ataagtggaa
     1441 aaaacaaaac tataaagcat tgttaaatcc tattaataca gagggttgtc aaagtaatat
     1501 tctcagtatt atacagttta aatcagtagt tccaactgat tatcgattcg ctcctataaa
     1561 atttgatttt tggaatttga ttaaagagag atttgacagt tctgtagact acagaacaaa
     1621 aataaataat attttatcaa aattaaaaag aaagaacagt ctttatttta aggattttaa
     1681 ttctaagata gaccagattg ataataccct aattgcaatt gaaaattata ttgcttctat
     1741 gtatgctact gaattggaga ctgatagttt agctgaaaat acatttggat atttcttagg
     1801 taatgaagag gaaaaagaaa aaataaaaga attatttatc ttgataaaat ctaaaataat
     1861 taccagttca gtagaaactg aaataattgc aaaaaactca attggattat atcaatctga
     1921 gttattaaaa gaatgggttc aggaaaataa aacatctatc ctttcttgtg agaaggaaga
     1981 agagttatta ggtgttttaa ccaagaaaat aatagatttt tcaaataaca aagagatgag
     2041 aaaactaagt atagaaaatc taaattatat ttctcaactc tggattaagg ggatttctta
     2101 ttttcaaata ttggaaagtt gtactgaaaa atcaattagt attgagaaaa gaggtaagtc
     2161 aaaaccaatt gatatgtctg acataatctc tatttgtgat aatggattag ggtatgaaac
     2221 atcaatggtt ttaaatgcga ttaataatat tcttgaaaaa ctagttggag aggaattgga
     2281 cgtattgact atgttaataa agaggctgaa atatgggcta cctctggaaa aagaaatcaa
     2341 tatctatgaa ttaggttttt cagatagaat tgtggtccaa gttattggtc aagagattaa
     2401 ttctgtaagt aagaatcaaa ttagaaatga aatcaaacag aaatcagcta gactagaaga
     2461 taaattgagt gattttccaa gttattatac acagataatt aatgaaatgt aatattgttg
     2521 ataaaaagga gaaaaaatga ctaaaatatc ttttgaaatc caacaacaaa ttattcaatg
     2581 ttttggatta tgttttcact ataaagatac tgtcgtttca tttatgcaaa cttcgggagt
     2641 tccaaatgat ttaatattaa aatggaaatc ggaaccgaag tttgtttggg cgaaaaatgt
     2701 tataaatgaa cttaataaaa cagaaaatgg aagattgata attagacgaa tagcaactga
     2761 attttataag atgaaaaata ttcctgatga agttcaagat agagatagag gattagatgc
     2821 gttaagaaaa ttaaagcgac tgataggtga tactcaacag aataaggtta acgaaacact
     2881 taataattct tatcatcgtt ccagacagga aatgaaaata caactcaggc aacaactcct
     2941 tcaaaaaatt gaagaactaa agacggagta ttattcgcta ttttcaagtg ataatcctca
     3001 agaaagagga tatcgtttag aaaaaattgt tgctaattta ttcagaatta atgatattga
     3061 ttaccatgat tcgtatagaa atagaacaaa tactcaacag ttagatggct attttaggtt
     3121 tgaaggtttt gattatttag ttgaaatgaa atgggaaaaa aatccagtaa attctccgaa
     3181 aatagcttct ttaaaacaaa aagttgatac aaaactaact tcgactcggg gactgtttct
     3241 ttcaataaat ggttttagag atgaagtaat acaagatttt tctaataaag atgctaaaat
     3301 tttatttatg gatggacaag aattagctta tattctagaa aatagaatta gtttgtacga
     3361 agctttaaaa gttaagataa ttggtgcttc taaaactggc aatccaaatg tttctataat
     3421 taatcaagaa taacttttcc gagagatatt aaaaccatca ataaaataga gcgatacttt
     3481 atatgccatg atacaaatga tatacaatga tacttctgac cgttcaggct gccatcgtaa
     3541 aagagcagca agtgaaattc ttatgatgac ttcatcagtc atgccacgtt aaatgtgtga
     3601 gtttgttaga gaaacgcaat taatcctcaa aaggttcccc gaaccttttg agttccacag
     3661 acgcatcacg tggagtgtgt aagcttgttg ctaaaagcgt aaaaaccttg gaacgaaagg
     3721 aataatagac ttcctgcgaa acaaaaatac aatacaataa aactatggat gatgaagcaa
     3781 gtaaacaatt aagcgatagc cgtttcaaga gccttgtagg tgttcagcgc acgagatgtt
     3841 agctgtgtta aaaacagctt atcaacgcaa cgtaaacgcg caaaaggtgg acgaaaaacc
     3901 aaattaagcc tagacgatct cctcatggta actattcaat acatgcgaga atagcacact
     3961 tatgaacaaa ttgcggctga ttttggcatt cacgaaagca acataattag tcggagtcaa
     4021 tggattgaag caactcttat tcaaaatggt tttacgattt caaattctgc cttaattctg
     4081 taaaaacagt aaaattcgaa ggattgtaag gtaagagttt ttttctttct gaaaaaatgg
     4141 tataatagca atcaaaacta gaaaataaaa cggaatttgg aacagatttg tctgtatcct
     4201 agtagagtgg tgatactatg aagattagta agaggcactt attaaattat tccatcttga
     4261 ttccctactt gcttttatct attttgggct tgattgtggt ctattcgacc accagtgcta
     4321 ttttaattga agaaggcaag agcgccttgc agttggttcg aaaccaagga atcttttgga
     4381 ttgttagttt gatactgatt gccttaattt ataaattgag actagatttt ttgagaaatg
     4441 agcgactaat cattttagtt atattaatag aaatgctttt attgttcttg gctcgtttta
     4501 ttggtatttc cgtaaacggg gcatacggtt ggatttcggt tgcaggaata actattcagc
     4561 cagctgagta cttaaaaatc attattattt ggtatttagc tcaccgattc tccaaacagc
     4621 aagaagaaat agctacttat gattttcaag ttttgactca aaatcaatgg cttccccgtg
     4681 cttttaatga ttggcgattc gttctcctag ttctgattgg aagtttggga attttccctg
     4741 atttaggaaa tgcgactatt ttagtcttgg tttccttgat tatgtataca gttagtggaa
     4801 tcgcttatcg ctggttttca accattctgg cgctcgtatc tgccgcttct gtctttgtct
     4861 tgaccactat cagcctaatc ggtgttgaga ccttttcaaa aattccagta tttggctatg
     4921 tagccaagcg ctttagtgcc ttttttaatc cttttgccga tcgtgctgat gcaggtcacc
     4981 agttagctaa ttcttatttt gccatggtca atggcggttg gtttggtcta ggtcttggaa
     5041 actcgattga aaaacgaggt tatttgccag aagctcatac agactttgtc ttttctatcg
     5101 tgattgaaga atttggcttt gttggtgcca gtcttatttt agctctctta tttttcatga
     5161 ttttgcggat tatcttggtc ggtatccgag cggagaatcc tttcaatgcc atggttgcac
     5221 tcggtgtcgg agggatgatg ttggttcagg tatttgtcaa tatcggaggg atttcgggct
     5281 tgattccatc tacaggagta accttcccct tcttatccca gggtggaaat agtcttctag
     5341 tcttatcagt ggcagtagcc tttgtcttaa atattgatgc cagtgaaaaa cgcgctaaat
     5401 tgtaccgaga attggaaaat caaccaatga accttctgtt gaagtaggat aaagaaagga
     5461 tagtttatgt ctcttcaaaa attagaaaat tatagtaata aaagtgttgt gcaagaagaa
     5521 gtcttgattc taacagaatt actggaagat attactaaaa atatgcttgc cccagagacc
     5581 tttgaaaaaa taatacagtt gaaagaatta tcaacgcagg aagattatca aggtctaaac
     5641 cgtctagtga ctagcttatc aaatgatgaa atggtctata tttcacgcta tttctctatc
     5701 ttgcctcttt tgattaatat ttcagaggat gtggatttag cttatgaaat caatcatcaa
     5761 aataatattg atcaggacta tttaggtaaa ttatctacaa cgattaaatt ggtagcagaa
     5821 aaggaaaatg ccgttgagat cctagaacac ttgaatgttg tccctgtttt gacagcccat
     5881 ccaacacaag tgcaacgcaa aagtatgttg gatttaacaa atcatattca tagtcttttg
     5941 cgtaaatacc gtgatgttaa gttggggttg attaataaag ataaatggta caatgatttg
     6001 cgtcgttaca tcgaaattat catgcagaca gacatgattc gtgagaaaaa attaaaagtg
     6061 actaacgaaa tcacgaatgc tatggaatat tataacagct cctttttgaa agctgtacct
     6121 catttgacga cggagtataa gcgcttagcg caagcgcatg gtctgaattt aaaacaggct
     6181 aaaccaatca ccatgggtat gtggataggt ggtgaccgtg atggaaatcc atttgttaca
     6241 gcaaagacct tgaagcagtc tgcactcact cagtgtgaag tcatcatgaa ctactatgat
     6301 aaaaagattt accaacttta tcgtgaattt tctctttcaa ctagcattgt caacgtcagc
     6361 aagcaagtca gagaaatggc tcgtcaatcc aaggataact cgatttaccg cgaaaaagag
     6421 ctttaccgtc gtgccttgtt tgatattcaa tcaaaaattc aggcaactaa aacctatctg
     6481 attgaggatg aagaagttgg gactcgttat gaaaccgcca atgatttcta caaggatttg
     6541 attgccattc gagattctct actagaaaat aagggtgagt ccttgatttc aggtgatttt
     6601 gtggaattat tgcaggcagt agagatattt ggtttttact tagcgtcaat tgatatgcga
     6661 caagactcta gcgtctatga agcctgtgtg gcagaactct tgaaatcagc aggaattcat
     6721 tctcgttata gcgagttgag cgaagaagaa aagtgtgacc ttctcttgaa agaattagaa
     6781 gaagatcccc gaattctttc tgcgactcac gcagaaaaat cagaattatt agcaaaagaa
     6841 ttagctattt ttaagacggc tcgtgttttg aaagataagt tgggagatga tgtcatccgt
     6901 cagaccatca tttcacatgc aaccagcctt tctgatatgc tagaattagc tattctgtta
     6961 aaagaagtag gactggtgga tacggaaagg gcgcgtgttc agattgttcc cctttttgaa
     7021 acaattgaag acttggatca ttcagaggaa acaatgagaa aatatctttc tcttagcctt
     7081 gccaaaaaat ggattgactc acgaaataac taccaagaaa tcatgcttgg ctactctgac
     7141 agtaataaag atggcggtta cctgtcatca tgttggaccc tctacaaggc tcaacaacaa
     7201 ttgactgcta ttggagatga atttggcgtt aaggttacct tcttccatgg tcgtggtggt
     7261 actgtcggtc gtggtggtgg gccaacctat gaagccatta catctcaacc gctcaagtct
     7321 atcaaggatc gtatccgctt gacggagcag ggtgaagtaa ttgggaataa atacggtaac
     7381 aaagacgccg cttactataa ccttgaaatg ctagtatcgg cagctattaa ccgtatgatt
     7441 actcagaaga agagcgatac caatacccca aatcgttatg aagccattat ggatcaagta
     7501 gtggaccgta gttacgatat ctaccgtgat ttggtctttg gtaatgagca tttctatgat
     7561 tatttcttcg agtcaagtcc aatcaaggct atttcaagtt ttaatattgg ttctcgtcca
     7621 gccgctcgta agactattac tgaaatcggt ggtttgcgtg ccatcccttg ggtattctca
     7681 tggtcacaga gtcgtgttat gttccctgga tggtacgggg ttggttcaag cttcaaggaa
     7741 tttatcaata aaaatccaga gaatattgct atcttacgag atatgtacca aaattggcct
     7801 ttcttccaat cgcttctttc aaatgttgat atggttttgt caaaatcaaa tatgaatatt
     7861 gcttttgaat atgctaaact ttgtgaagac gagcaagtta aggccatcta tgagactatt
     7921 ttaaatgaat ggcaagttac taagaacgtt atcttggcta ttgaaggaca tgacgaactc
     7981 ttagctgaca atccatatct aaaagctagt ctggattacc gtatgcctta ctttaatatt
     8041 ctcaactata ttcagttaga gttgattaaa cgccaacgtc gtggagaatt gtccagtgat
     8101 caagaacgat tgattcatat caccatcaac ggaattgcga caggattgcg taattcaggt
     8161 tgataatttt caagagtgaa tgctaaaagt gaatatcaaa aaaattctaa tagactattg
     8221 acaagtagtt taaaaatgat ataatttaac cattcagaaa agtaatcata caaacttttt
     8281 agagagtctg tggtagctga aaacagataa gtggcgatga tgaaaattgg gctgaatgct
     8341 atttagaatt tgaaattata aaaattcggt aagcacacct tacagtgcat ctcgttattg
     8401 cgagactgag cgatagggaa attccctata attgaggtgg taccgcgcat cgacgtcctc
     8461 acacaagttt tttgtgtgag gatttttttg atggaggtta gtatggaaag aaaacgatgg
     8521 cgtcgcttgt ttagataagt gaaatatgtt aaaggaaata aaaaggagaa acagaatgaa
     8581 aaataaacgt ttaattggaa ttattgctgc attagcagtc ttagtagcag gaaacttgat
     8641 ttattcttca atgaataaat cagaagttca gaataataag gatgagaaga aaataaccaa
     8701 gattggtgtg cttcaatttg tgagccatcc atcccttgat ttgatttata aagggatcca
     8761 agatggactt gcagaagaag gatataaaga tgatcaagtt aaaattgatt ttatgaactc
     8821 agaaggtgac caaagtaagg ttgcgacaat gagtaaacaa ttggttgcaa atggaaatga
     8881 ccttgtggtt ggtatcgcaa caccagcagc ccaagggttg gctagtgcaa caaaagacct
     8941 accggttatc atggccgcta ttacagaccc aattggtgct aacttggtta aagatttgaa
     9001 aaaaccaggt ggcaacgtta caggggtatc tgaccacaat ccagctcaac aacaagttga
     9061 actcatcaag gctctgacac cgaatgtgaa aacaatcgga gctctttact caagtagcga
     9121 agacaattca aaaacacagg tcgaagaatt taaggcttat gctgaaaaag caggtctgac
     9181 agtggaaaca tttgcagttc cttcaacaaa tgaaattgcc tcaactgtca ctgttatgac
     9241 tagcaaggta gatgctattt gggttccaat tgataacacc attgcatcag gatttccaac
     9301 ggttgtctct agcaatcaaa gttctaagaa accaatttat cccagtgcga cagctatggt
     9361 agaagtaggt ggtttggcat cagttgtaat tgaccaacat gaccttggtg tggcaacagg
     9421 taaaatgatt gtgcaagtct tgaaaggtgc aaaaccagcc gataccccag tcaatgtctt
     9481 ttcaattggt aagtcagtca tcaataaaaa aatagcacaa gaactaggta ttactattcc
     9541 tgagtctgtt ctcaaagaag caggacaagt catcgaataa ataaggtagg gaggaggaga
     9601 ctcttcccat tttttaaaaa gatgaatata gaaaggatta aataaaatat gattgtttcc
     9661 attatttctc aaggatttgt ctgggctatt ctaggtctgg gaatctttat gacatttagg
     9721 attttaaact ttccagatat gacgacagaa ggttccttcc ctcttggggg agctgttgct
     9781 gtcactttga taaccaaagg cgtgaaccca tttttagcga cacttgttgc tgtaggagca
     9841 ggttgtttgg ctggaatggc agcaggcctt ctttatacaa aagggaagat cccaaccttg
     9901 ctctcaggga ttttggtgat gacttcttgt cactcaatca tgctcttgat tatgggacgt
     9961 gcgaatttag gcctgcttgg aaccaagcaa attcaggatg ttttgccttt tgattcggat
    10021 ttgaatcaac tcttgacagg tctcatcttt gtgagcattg ttattgctct catgctcttt
    10081 ttcttggaca ctaaactcgg acaagcctat attgctacag gggataatcc tgatatggct
    10141 agaagtttcg ggattcatac tggacgcatg gagctcatgg gcttggtctt atcaaatggt
    10201 gtgattgccc ttgcaggtgc cctcattgct cagcaagaag gttatgccga tgtgtctcga
    10261 gggatcgggg ttatcgttgt ggggcttgca agtttgatta ttggagaagt tattttcaag
    10321 agtttgagct tggcagagcg tttggttact atcgttgtag gttctatcgc ttatcaattt
    10381 ttagtgtggg cagttatcgc acttggcttt aatacaagtt accttcgttt atacagtgcc
    10441 ttgattttag cagtctgcct catgattcca acatttaagc aaacaatctt gaaaggagcc
    10501 aagttaagca aatgacagca attgtagaat taaaaaatgc aaccaaaatc gttaaaaatg
    10561 gctttgatga agaaaagatt attttaaatg atgtttcctt agaaattttt gaacgggact
    10621 ttatcacgat tttgggcgga aatggtgctg gaaaatcaac cctctttaac actatagcag
    10681 ggaccttatc actaactagt ggaactatcc gtattttagg tgaagatctc actaagtttt
    10741 cacccgagaa gcgtgccaag tacctgtctc gtgtcttcca agatccaaag atggggacag
    10801 ctccccgtat gacggtcgct gaaaatcttt taatcgccaa gtttcgtggt gaaaagcgtg
    10861 gattgttacc aagacgcttg actagctata aggatgaatt tcaggcaacc attgaaaaag
    10921 taggaaatgg tcttgagaaa cacttgaata caccgattga gttcttatca ggtggacaaa
    10981 gacaggcttt gagtctcttg atggcaacct tgaagcgacc tgaattactc ttgttagacg
    11041 agcatactgc tgccctggat ccaaagacta gtgttgcttt gatggaattg acagatgaat
    11101 ttgttaagaa agatcagcta acagccctta tgattactca tcatatggaa gatgctctca
    11161 aatacggcaa tcgcttgatt gtcatgaaag aaggacggat tatccaagat ttaaaccaag
    11221 aagaaaaagc aaaaatgaaa atctctgatt attatcaact ctttgaataa agtaaggaaa
    11281 atgagtgaaa tggtttactt tttttctgaa ataaagtata ctatataaag taaactatga
    11341 taacatggag gtattgtgta tggttgacaa acaagtcatt gaagaaatca aaaacaatgc
    11401 caacattgtg gaagtcatag gagatgtgat ttctttacaa aaggcaggac ggaactatct
    11461 agggctctgt ccttttcatg gtgaaaaaac accttctttc aacgttgtag aggataagca
    11521 gttttatcac tgtttcggtt gtggtcgctc aggtgatgtc tttaagttca tagaggagta
    11581 ccaaggggtt ccctttatag aggcagtcca aatcttaggt cagcgtgttg gaattgaggt
    11641 tgaaaaaccg ctttatagtg agcaaaagtc agcctcacct caccaagatc tttatgatat
    11701 gcacgaagat gcagccaaat tttaccatgc tattctcatg acaacgacta tgggcgaaga
    11761 ggccagaaat tacctttatc agcggggttt gacagatgaa gtgcttaaac atttttggat
    11821 tggtttagca cctccagaac gaaactatct ctatcaacgt ttgtctgatc agtatcgtga
    11881 agaggattta ctggattcag gcctgtttta tctctcggat gccaatcaat ttgtagacac
    11941 ctttcacaat cgcattatgt ttcccctgac aaatgaccaa ggaaaggtca ttgccttctc
    12001 aggtcgtatc tggcaaaaaa cggattcaca aacttctaag tataaaaaca gccgatcgac
    12061 tgcaattttt aacaaaagtt acgaattata tcatatggat agggcaaaaa gatcttctgg
    12121 aaaagctagt gagatttacc tgatggaagg attcatggat gttattgcag cctatcgggc
    12181 tggaatcgaa aatgctgtgg cgtcgatggg aacggccttg agtcgagagc atgttgagca
    12241 tctgaaaagg ttaaccaaga aattggttct tgtttacgat ggagataagg ctgggcaagc
    12301 cgcgacattg aaagcattgg atgaaattgg tgatatgcct gtgcaaatcg ttagcatgcc
    12361 tgataacttg gatcctgatg agtatctaca aaaaaatggt ccagaagact tggcctatct
    12421 attaacgaaa actcgtatta gtccgattga gttctacatt catcagtaca aacctgaaaa
    12481 cagtgaaaat ctgcaggctc agattgagtt tcttgaaaaa atagctccct tgattgttca
    12541 agaaaagtcc atcgctgctc aaaacagcta tattcatatt ttagctgaca gtctggcgtc
    12601 ctttgattat acccagattg agcagattgt taatgagagt cgtcaggtgc aaaggcagaa
    12661 tcgcatggaa agaatttcca gaccgacgcc aatcaccatg cctgtcacca agcagttatc
    12721 ggctattatg agggcagaag cccatctact ctatcggatg atggaatccc ctcttgtttt
    12781 gaacgattac cgtttgcgag aagactttgc atttgctaca cctgaatttc aggtcttata
    12841 tgacttgctt ggccagtatg gaaatcttcc tccagaagtt ttagcagagc agacagagga
    12901 agttgaaaga gcttggtacc aagttttagc tcaggatttg cctgctgaga tatcgccgca
    12961 ggaacttagt gaagtagaga tgactcgaaa caaggctctc ttgaatcagg acaatatgag
    13021 aatcaaaaag aaggtgcagg aagctagcca tgtaggagat acagatacag ccctagaaga
    13081 attggaacgt ttaatttccc aaaagagaag aatggagtaa taatggcaac aaaacaaaaa
    13141 gaagtaacaa catttgacgt acaggtagca gaatttatcc gtaatcataa gcaaaaaggg
    13201 acagcaacag atgatgaaat caatgcaagt ctggttattc cttttacctt ggacgctgat
    13261 gggattgaag atctcttgca acggattcag gatgcaggga tttctatcac agataacgaa
    13321 ggaaatccaa gtgcgcgtgt tcttagcaat gaagaagaac cagaactcag cgatgaggac
    13381 ttgattggat caacttctgc taaggtcaat gaccctgtcc gtatgtactt gaaagaaata
    13441 ggggtcgttc ctctcttgac caatgaagag gagaaagagt tggcactggc tgttgaagct
    13501 ggcgatatcg aagccaaaca acgtcttgcg gaagccaatc ttcgtttggt tgtttccatt
    13561 gccaaacgct atgtcggtcg tggcatgcag ttccttgact tgattcaaga aggaaatatg
    13621 ggcttgatga aggcggttga caagtttgac tattctaaag ggttcaagtt ttcaacttat
    13681 gcaacttggt ggattcgtca ggctatcact cgtgctattg cggaccaagc tcgtaccatc
    13741 cgtatcccag ttcacatggt tgaaactatc aataaattgg ttcgtgaaca gcggaatctc
    13801 cttcaagaat tggggcaaga tccgacacca gaacagattg ctgaacgaat ggatatgaca
    13861 cctgataagg ttcgtgaaat cttgaagatt gcccaagaac cagtatctct tgaaactcct
    13921 atcggtgaag aggacgatag ccaccttgga gactttatcg aagatgaagt gattgaaaat
    13981 ccagtggatt atacgactcg tatcgtcttg cgtgagcaat tggatgaaat cttagatact
    14041 cttacagacc gtgaagaaaa tgttctgcgt ctacgttttg gactagatga tggaaaaatg
    14101 cgcacacttg aagatgtggg gaaagtcttt aacgtaactc gtgagcgtat ccgtcagatt
    14161 gaagcaaagg ctttgagaaa actacgccaa ccaagccgca gcaaaccgct tcgtgatttt
    14221 attgaagact aagagtgagg aaaatatggc ttatacagaa gagcaaattg aaaacatcaa
    14281 aacacggatt ttaacagcct tggaagaagt catcgaccct gagttgggaa tcgatattgt
    14341 caatcttggt ttgatctatg agattcgttt tgacggtgac acagggcaaa cagagattga
    14401 catgactttg acaactatgg gttgtccctt agcagacctt ttgacagacc agatttatga
    14461 tgctatgata gaggttccag aagtaacgga tactgaggtt aaattagtct ggtatccagc
    14521 ctggacagtt gaaaaaatga gtcgctatgc ccgcattgcc ctaggcatta agtaaacata
    14581 taaaagcatg tgagagactg ttggaaaagc gaggaaattt cccctctttt cctctagtct
    14641 ctcctttctt ttgctgattt tattcaaaga aaatgatata atagtagtta tggagaaaaa
    14701 gaaattacgc atcaatatgt tgagttcaag tgagaaagta gcaggacagg gagtttcagg
    14761 tgcttaccgt gaattagttc gtcttcttca ccgtgctgcc aaggaccaat tgattgttac
    14821 agaaaatctt ccgatcgagg cagatgtgac tcactttcat acgattgatt ttccctatta
    14881 tttatcaacc ttccaaaaga aacgctcagg gagaaagatt ggctatgtgc atttcttgcc
    14941 agctacactt gagggaagtt tgaaaattcc atttttctta aaggaaattg tgaaacgcta
    15001 tgtattttct ttttacaacc ggatggagca cttggttgtg gtcaatccta tgtttattga
    15061 ggatttggta gcagctggta ttccacgtga aaaagtgacc tatattccta actttgtcaa
    15121 caaggaaaaa tggcatcctc taccacaaga agaggtagtt agactgcgca cagatcttgg
    15181 tcttagtgac aatcagttta tcgtagtagg tgctgggcaa gttcagaaac gtaaagggat
    15241 tgatgacttt atccgtctgg ctgaggaatt gcctcagatt acctttatct gggctggtgg
    15301 cttctctttt ggtggtatga cagatggtta tgaacactat aagaaaatta tggaaaatcc
    15361 ccctaaaaat ttgatttttc caggcattgt atcgccagag cggatgcgcg aattgtatgc
    15421 tctagcggat cttttcttgt tgcctagtta caatgagctc tttcctatga ctattttaga
    15481 agctgcgagt tgtgaggctc ctattatgtt gcgtgattta gatctctata aggtgatttt
    15541 ggagggaaat tatcgggcga cagcgggtag agaagagatg aaagaggcta ttttggaata
    15601 tcaagcaaat cctgctgcct taaaagatct caaagaaaag gctaagaata tttccagaga
    15661 gtattctgaa gagcatctgt tacaaatctg gttggacttt tatgagaaac aagccgcttt
    15721 agggagaaag taaaaagtga ggtaatctat gcgaattggt ttatttacag atacctattt
    15781 tcctcaggtt tctggtgttg cgaccagtat tcgaaccttg aaaacagaac ttgaaaagca
    15841 gggacatgct gtttttatct ttacgacgac agataaggat gtcaatcgct acgaagattg
    15901 gcaaattatc cgcattccaa gtgttccttt ctttgctttt aaggatcgtc gctttgccta
    15961 ccgaggtttt agcaaggcac ttgaaattgc taaacagtat cagctagata ttatccatac
    16021 tcagacagaa ttttctcttg gcctgttggg gatttggatt gcgcgtgaat tgaaaattcc
    16081 agtcatccat acctatcaca cccagtatga agactatgtc cattatattg ctaaggggat
    16141 gttgatccgg ccgagtatgg tcaagtatct ggttagaggt ttcctgcatg atgtggatgg
    16201 ggttatttgt cctagtgaga ttgtccgtga cttgctatct gattataagg tcaaggttga
    16261 aaaacgggtc attcctactg ggattgaatt agccaagttt gagcgtccgg aaatcaagca
    16321 ggaaaatttg aaagaactgc gtagtaaact agggattcaa gatggtgaaa agacgttgct
    16381 tagtctttcg agaatctcct atgaaaaaaa tattcaagca gttttagcag ccttttctga
    16441 tgttctgaaa gaggaagaca aggttaaact ggtagtagct ggggatggcc cttatctgaa
    16501 tgacctcaaa gagcaagctc agaacctaga gattcaagac tcagtcatct ttacagggat
    16561 gattgctcct agtgagacgg ctctttacta taaagcggcg gatttcttca tttcggcatc
    16621 gacaagcgaa acgcaaggtt tgacctactt ggaaagctta gccagtggaa cacctgtcat
    16681 tgctcacgga aatccttatt tgaacaacct catcagtgat aaaatgtttg gaaccttgta
    16741 ctatggagaa catgatttgg ctggtgctat tttggaagcc ctgattgcaa caccagacgt
    16801 gaacgagcat accttatcag agaaattgta tgagatttca gctgagaact ttgggaaacg
    16861 agtgcatgag ttttatctgg atgccattat ttcaaataac ttccagaaag atttggctaa
    16921 agatgatacg gtcagtcagc gtatctttaa gacagttttg tatcttcagc aacaggtggt
    16981 tgctgtacct gtaaaaggat ctagacgcat gttgaaggct tcaaaaacac agttgatcag
    17041 tatgagagac tattggaaag accatgaaga atagaaagag gaacagctat gaaaaaaaca
    17101 attaatgaga agcggtcgtg ataaaaagat tgcgggtgtt tgtgctgggg tggcccatta
    17161 tctggatatg gatccgacta tcgttcaagt catttggggt gttcttactt gctgttacgg
    17221 agctggaatt gtagcttaca ttattttatg gattatcgca ccagtagcaa ctgactattg
    17281 aaaactagct caattcatgc taagataata gaaaatagaa tgtaacgaag gagagaaaaa
    17341 tggcatttgg agataatgga aatcgtaaaa aaactatgtt tgagaaaata accttgttta
    17401 tcgtgattat catgctagta gcaagtttat tgggaatttt tgcaactgca attggtgccc
    17461 tcagtagtct ataaaataga ttcaagaaaa tttagtgact gggatttccc agcccttttt
    17521 taaagtgaga agaaataatg agtatgtttt tagatacagc taagattaag gtcaaggctg
    17581 gtaatggtgg cgatggtatg gttgcctttc gtcgtgaaaa atatgtccct aatggaggcc
    17641 cttggggtgg tgatggtggt cgtggaggca atgtggtctt cgttgtagac gaaggactac
    17701 gtaccttgat ggatttccgc tacaatcgtc atttcaaggc tgattctggt gaaaaaggga
    17761 tgaccaaagg gatgcatggt cgtggtgctg aggaccttag agttcgagta ccacaaggta
    17821 cgactgttcg tgatgcggag actggcaagg ttttaacaga tttgattgaa catgggcaag
    17881 aatttatcgt tgcccacggt ggtcgtggtg gacgtggaaa tattcgtttc gcgacaccaa
    17941 aaaatcctgc accggaaatc tctgaaaatg gagaaccagg tcaggaacgt gagttacaat
    18001 tggaactaaa aatcttggca gatgtcggtt tagtaggatt cccatctgta gggaagtcaa
    18061 cacttttaag tgttattacc tcagctaagc ctaaaattgg tgcctaccac tttaccacta
    18121 ttgtaccaaa tttaggtatg gttcgcaccc aatcaggtga atcctttgca gtagccgact
    18181 tgccaggttt gattgaaggg gctagtcaag gtgttggttt gggaactcag ttcctccgtc
    18241 atatcgagcg tacacgtgtt atccttcaca tcattgatat gtcagctagc gaaggccgtg
    18301 atccatatga ggattaccta gctatcaata aagagctgga gtcttacaat cttcgcctca
    18361 tggagcgtcc acagattatt gtagctaata agatggacat gcctgagagt caggaaaatc
    18421 ttgaagaatt taagaaaaaa ttggctgaaa attatgatga atttgaagag ttaccagcta
    18481 tcttcccaat ttctggattg accaagcaag gtctggcaac acttttagat gctacagctg
    18541 aattgttaga caagacacca gaatttttgc tctacgacga gtccgatatg gaagaagaag
    18601 cttactatgg atttgacgaa gaagaaaaag cctttgaaat tagtcgtgat gacgatgcga
    18661 catgggtact ttctggtgaa aaactcatga aactctttaa tatgaccaac tttgatcgtg
    18721 atgaatctgt catgaaattt gcccgtcagc ttcgtggtat gggggttgat gaagcccttc
    18781 gtgcgcgtgg agctaaagat ggggatttgg tccgcattgg taaatttgag tttgaatttg
    18841 tagactagga gactggtatg ggagataaac cgatatcttt ccgagatgcg gatggtaatt
    18901 ttgtttccgc cgcagacgtt tggaatgaaa agaaattgga agaactattt aatcgtctca
    18961 atccaaatcg tgccttgaga ttggcacgaa ctaaaaagga aaatccatct cagtaaagaa
    19021 gctaaaaaat cccgtgcctc atcagacacg ggattttgtg gtacgacggg catgtatagc
    19081 gaactgaatc tggaatagca cagcatatct tctaaaatat agtaaaatga aatgagaaca
    19141 ggacaaatcg atcaggacag taaaatcgat ttctaacaat gttttagaag cagaggtgta
    19201 ctattctagt ttcaatcaac tatattgtta taaattgatt tgaatttcaa aattaaattg
    19261 tttgattctt atttcaattt gttatagtat atctgatgtc aaagttctcg gcgagtcaaa
    19321 tagcgattcc caagcctgac tatcgtgagg tagcggatta aaatggtctg gggatagacc
    19381 gttttaagtc tgacgctgga aataagaatt gtcagaagaa gggatagcga actcgtggct
    19441 ctacgaacag gaacgtgata ataaggcgta tatagcggat aagagggcct caaactctaa
    19501 agtccaaaaa ggtattcgta acctatatgc gtaaattacg agagtaattg aattcgtact
    19561 aagattttct attttcactg taagctttta acgcccttat atcttgtata cacgaggaaa
    19621 gatgtacgac ttatcccgtg aggtctatca ctataaagag aaaacgacag atagaagtga
    19681 tcctgagtca cggttatctt taaaatagat tgtctgatag gacggtatgt ataaaacgct
    19741 tctgtgaact gagagaaggg ggagaagttc ttgctaaaat ttagttgaac agccgtattc
    19801 cgatacttag ataagagatc tagtcttagc tcctactcag ttttagggga taaaaaaggg
    19861 gcaatagcga ttcgagaaag attatactct tcgaaaatct cttcaaatca cgtcaatatc
    19921 gccttgccgt atgtgtagga tactgactac gtcagttcca tctacaatct caaaacagtg
    19981 ttttgagcaa cctgcggcta gtttcctagt ttgatctttg atttttattg agtattagta
    20041 attcagttac taactcgtca actctgattt atccaataaa attgaaaagg atggaaaaaa
    20101 ggataaattt atgatatact ttattttgaa gaccttatta gaaatcttga aagagtattg
    20161 aaaacttaga atgagaaaaa ttgttatcaa tggtggatta ccactgcaag gtgaaattac
    20221 tattagtggt gctaaaaata gtgttgtggc cttaattcca gctattatat tggctgatga
    20281 tgtggtgact ttggattgtg ttccagatat ttcggatgta gccagtcttg tcgaaatcat
    20341 ggaattgatg ggagctactg ttaagcgtta tgacgatgtc ttggagattg atccaagagg
    20401 tgttcaaaat attccaatgc cttatggtaa aattaacagt cttcgtgcat cttactattt
    20461 ttatgggagc ctcttaggcc gttttggtga agcgacagtt ggtctaccgg gaggatgtga
    20521 tcttggtcct cgtccgattg acttacacct taaggcgttt gaagctatgg gtgccactgc
    20581 tagctacgag ggagataaca tgaagttatc tgctaaagat acaggacttc atggtgtaag
    20641 tatttacatg gatacggtta gtgtgggagc aacgattaat acgatgattg ctgcggttaa
    20701 agcaaatggt cgtactatta ttgaaaatgc agcccgtgaa cctgagatta ttgatgtagc
    20761 tactctcttg aataatatgg gtgcccatat ccgtggggca ggaactaata tcatcattat
    20821 tgatggtgtt gaaagattac atgggacacg tcatcaggtg attccagacc gcattgaagc
    20881 tggaacatat atatctttag ctgctgcagt tggtaaagga attcgtataa ataatgttct
    20941 ttacgaacac ctggaagggt ttattgctaa gttggaagaa atgggagtga gaatgactgt
    21001 atctgaagac agcatttttg tcgaggaaca gtctaatttg aaagcaatca atattaagac
    21061 agctccttac ccaggctttg caactgattt gcaacaaccg cttacccctc ttttactaag
    21121 agcgaatggt cgtggtacaa ttgtcgatac gatttacgaa aaacgtgtaa atcatgtttt
    21181 tgaactagca aagatggatg cggatatttc gacaacaaat ggtcatattt tgtacacggg
    21241 tggacgttat ttacgtggga ccagtgttaa agcgaccgac ttaagagctg gggctgcact
    21301 agtcattgct gggcttatgg ctgaaggtaa aactgaaatt accaatatcg agtttatctt
    21361 acgtggttat tctgatatta tcgaaaaatt acgtaattta ggagcggata ttagacttgt
    21421 tgaggattaa accgtagagg tgtttatgaa tatttggacc aaattagcaa tgttttcttt
    21481 ttttgaaacg gatcgcttgt atttgcgtcc tttctttttt agtgatagtc aggacttccg
    21541 cgagatagct tcaaatccag aaaatcttca atttattttc ccaacgcagg caagtctgga
    21601 agaaagtcaa tatgcactgg ccaattactt tatgaagtcc cctttgggag tgtgggcaat
    21661 ttgtgaccag aaaaatcaac aaatgattgg ttctattaaa tttgagaagt tagatgaaat
    21721 caaaaaagaa gctgagcttg gctatttttt gagaaaagat gcttggtcgc aaggatttat
    21781 gacagaggtt gttagaaaaa tttgtcagct ttcttttgag gaatttggct taaaacaatt
    21841 atctatcatt acccaccttg aaaatgaagc tagccaaaga gttgctctta agtctggatt
    21901 tagtttgttc cgtcagttta agggaagtga tcgttacaca agaaaaatgc gggattatct
    21961 tgaatttcgg tatgtaaaag gagagttcaa tgagtaagca tcaggaaatt ctaagctatt
    22021 tggaggaatt accagtaggt aaaagggtca gtgttcgtag catttcgaat catctaggag
    22081 ttagtgatgg aacagcctat cgggctatta aagaagctga aaaccgtgga attgtggaga
    22141 cccgtcctag aagtggaaca attcgtgtta aatcccagaa agttgctata gagagattaa
    22201 cgtttgctga aattgcagaa gtgacttctt ctgaggttct ggctgggcaa gaaggtttag
    22261 agagagaatt tagtaagttt tcaattggtg ccatgactga acaaaatatc ttgtcttacc
    22321 ttcatgatgg ggggctcttg attgtcggag accgaacccg tattcagtcg ctagccttgg
    22381 aaaatgaaaa tgcagttctg gttacagggg gatttcaggt tcatgatgat gtgcttaaac
    22441 tggccaatca aaaagggatc cctgttctaa gaagtaagca tgataccttt accgtcgcga
    22501 ccatgatcaa taaagccttg tcaaatgtcc aaatcaagac tgatattctg acagttgaga
    22561 aactttatcg ccctagtcat gagtatggtt ttctgagaga gacagataca gttaaagatt
    22621 atttggactt ggttcgtaag aatcgtagca gccgtttccc tgttatcaat caacatcagg
    22681 tcgttgttgg cgttgtaacc atgagagacg ctggtgataa atcaccaagc acgacaattg
    22741 ataaggttat gtctcgtagt ctatttttgg ttggattatc gacaaatatt gccaatgtga
    22801 gtcaacggat gatcgcagaa gactttgaaa tggtaccagt tgttcgaagc aatcaaactt
    22861 tgcttggcgt tgtgacgcga cgagatgtca tggagaagat gagccgttcc caagtttcgg
    22921 ctctaccaac tttttctgag cagattggac aaaagctctc ttatcaccat gatgaagtag
    22981 tcattacagt ggaacccttt atgctagaaa aaaatggagt tttggctaat ggtgtattgg
    23041 cagaaattct gacccacatg acccaagatt tagttgttaa tagtggtcgc aatctcatta
    23101 tcgagcagat gctgatctac tttttgcagg ctgttcagat agatgatata ttgcgcattc
    23161 aggcacggat tattcatcat acgagacggt cagctataat tgattacgat atttatcatg
    23221 gtcaccagat tgtttcaaaa gcaaatgtga ctgttaaaat taattagaaa ctaggagaaa
    23281 agatgataac attaaaatca gctcgtgaaa tcgaagctat ggacaaggct ggtgattttc
    23341 tagcaagtat tcatataggc ttacgtgatt tgattaagcc aggcgtagat atgtgggaag
    23401 ttgaagaata tgtccgccgt cgttgtaaag aagaaaattt ccttccactt cagattgggg
    23461 ttgacggtgc catgatggac tatccttatg ctacctgttg ctctcttaac gatgaagtgg
    23521 ctcacgcttt ccctcgtcat tatatcttga aagatggtga tttgctcaaa gttgatatgg
    23581 ttttgggagg tcccattgct aaatccgacc tgaatgtctc aaaattaaac ttcaacaatg
    23641 ttgaacaaat gaaaaaatac actcagagct attctggtgg tttagcagac tcatgttggg
    23701 cttatgctgt tggtacaccg tccgaagaag tcaaaaactt gatggatgta accaaagaag
    23761 ctatgtacaa gggtattgag caagctgttg ttggaaatcg tatcggtgat atcggtgcgg
    23821 ctattcaaga atacgctgaa agtcgtggtt acggtgtagt gcgtgatttg gttggtcatg
    23881 gtgttggccc aactatgcac gaagaaccaa tggttcctaa ctatggtatt gcaggtcgtg
    23941 gactccgtct tcgtgaagga atggtcttaa ccattgaacc aatgatcaat acaggcgatt
    24001 gggaaattga tacagatatg aaaactggtt gggcgcataa gaccattgac ggtggattgt
    24061 catgtcagta tgaacaccaa tttgtcatta cgaaagatgg acctgttatc ttgactagcc
    24121 aaggtgaaga aggaacttat taataaaaag tgaaaagact actggaagtt tattttgata
    24181 aaaaatccag tagatctttt cataataaaa cgcattgtat caagtgttag gggctgatat
    24241 catgcgtttt tctgctttta agattttttc caactctgtt tgtaagcgca tcataacaaa
    24301 gggtctagga ttcagggctc tcctcctata tactattagt aaagtaaaac taagggagga
    24361 tattttagtg tcgcagtcta ttgttcctgt agagattcca caatattgtc gttttgattc
    24421 taaaaagaga aatggaattc tgtttaacgt ttgtattgcc aatcttaaat ttattttttt
    24481 atatta
//
LOCUS       DAVIME010000029        22552 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVIME010000029 DAVIME010000000
VERSION     DAVIME010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.029"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..1343)
                     /locus_tag="VV588_001304"
     CDS             complement(join(<1..902,902..1343))
                     /locus_tag="VV588_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU7083643.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKEIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKS"
     gene            complement(1436..2767)
                     /locus_tag="VV588_001305"
     CDS             complement(1436..2767)
                     /locus_tag="VV588_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU7083644.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLTDKE
                     ELVELLTRCAQNYQLRYEEFDYLASLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(2789..4300)
                     /locus_tag="VV588_001306"
     CDS             complement(2789..4300)
                     /locus_tag="VV588_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU7083645.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(4509..5456)
                     /gene="arcC"
                     /locus_tag="VV588_001307"
     CDS             complement(4509..5456)
                     /gene="arcC"
                     /locus_tag="VV588_001307"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU7083646.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(5621..6637)
                     /gene="argF"
                     /locus_tag="VV588_001308"
     CDS             complement(5621..6637)
                     /gene="argF"
                     /locus_tag="VV588_001308"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU7083647.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(6695..7924)
                     /gene="arcA"
                     /locus_tag="VV588_001309"
     CDS             complement(6695..7924)
                     /gene="arcA"
                     /locus_tag="VV588_001309"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU7083648.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            8680..10359
                     /locus_tag="VV588_001310"
     CDS             8680..10359
                     /locus_tag="VV588_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU7083649.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(10399..12483)
                     /locus_tag="VV588_001311"
     CDS             complement(10399..12483)
                     /locus_tag="VV588_001311"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU7083650.1"
                     /translation="MKPLLETIDTRLGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEANRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            12654..13934
                     /locus_tag="VV588_001312"
     CDS             12654..13934
                     /locus_tag="VV588_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU7083651.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            14025..16670
                     /locus_tag="VV588_001313"
     CDS             14025..16670
                     /locus_tag="VV588_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU7083652.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKVLHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            16754..17623
                     /locus_tag="VV588_001314"
     CDS             16754..17623
                     /locus_tag="VV588_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU7083653.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQTCTYHADANLY
                     GALVNWLQEEKQW"
     gene            17617..19497
                     /locus_tag="VV588_001315"
     CDS             17617..19497
                     /locus_tag="VV588_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU7083654.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVTIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            19851..20213
                     /locus_tag="VV588_001316"
     CDS             19851..20213
                     /locus_tag="VV588_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083655.1"
                     /translation="MPKTKTLAKLADVILWSFDFANDHAHAFFMDNVEWSHADSYFFS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(20265..20654)
                     /locus_tag="VV588_001317"
     CDS             complement(20265..20654)
                     /locus_tag="VV588_001317"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU7083656.1"
                     /translation="MKAQAIVTSQGRIVSLDITVNYCHDMKLFKMSCRNIGQAGKILA
                     DSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKACNHALSKERSKVENIFAKVKTFKIIS
                     TTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            complement(20680..20886)
                     /locus_tag="VV588_001318"
     CDS             complement(20680..20886)
                     /locus_tag="VV588_001318"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU7083657.1"
                     /translation="MREYRTYEEIAADFGIHESNFIRRSQWVEVTLVQSGFTVSRTPL
                     SSEDTVMIDATEVKINRPKKTISE"
     gene            complement(21069..21245)
                     /locus_tag="VV588_001319"
                     /pseudo
     CDS             complement(21069..21245)
                     /locus_tag="VV588_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            21580..>22552
                     /gene="pcpA"
                     /locus_tag="VV588_001320"
     CDS             21580..>22552
                     /gene="pcpA"
                     /locus_tag="VV588_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU7083658.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISL"
BASE COUNT         6493 a         4564 c         4910 g         6585 t
ORIGIN      
        1 ggatttagtt ctgtactgca cagaactaag tccttttagt tttaccttaa ttcgtttgtt
       61 gttgtagtaa tcaatgtagt ccacaatagc ttgttcaagg ttttctaaag atctaaagtt
      121 cttctcatag ccataaaaca tttcggattt taaaatgcca aagaaagatt ccatcatgcc
      181 gttgtctggg ctgttgccct tgcgtgacat ggatgcttga atttccttac tctctaggaa
      241 ccgatgataa gaatcgtgtt ggtattgcca gccttggtca ctatggagaa tcgtattctc
      301 atagtatttc tctgtaaagg cctgttctaa catactcttc acttgttcta agtttggcga
      361 agtagaaaga tgataagcaa tgatttcact gttaaaacca tctaaaactg gtgataaata
      421 gagtttctgt gtgctatttg gaatggcaaa ctctgtcaca tctgtatagc acttttccat
      481 tggcctcgat gcttcgaact ggcgttgaat gagattctct gctttcttgc caatctctcc
      541 ttggtaggaa gaatacttcc gtttacggcg aattcgagcc gttaaaccaa gaattctcat
      601 caaccgttga actttcttat gattgaccac aaaaccacga ttccttagtt ctaaatggat
      661 tcgacgatag ccatagttgc ctttatgttc attatcaatg ccctgaattt cggttttaat
      721 ctctttatct ttatcaaccc catccagttg tttcaactga taatagtaag tcgagcgagc
      781 taaacgtgct gtttcaagaa gaaaatctag tcgaaatcct cctgaaacca tttctctaac
      841 tgtctctgcc tttctcgctc tagggcttcg tccctttcct ctaactcttt taactttttt
      901 aggtaggcca cctcagtccg taagcgttca ttctcctcct ggagtcgttc tagttctgtc
      961 atttcttccc aagtcttctt ccgtttacgt cccattttag ctggtctccc tcttgttttc
     1021 tcaacaatag tatacccgtt tttcttgtat tgtgccggcc aaaatgaaag cattccttgg
     1081 tttgggaggg cataatcaag actaatactt ctttgtgaac aaccttccag taaggcttta
     1141 tccatcattt cttgtttcaa tttagaagaa tagtgacgat tcttcccttt tttaacgatt
     1201 tctatgccat aacggtcaat taatttcacc atgtacttta gaccagaaac atccacacca
     1261 aatctttttg aaagctgttt gaagctttgt ccttgctttc ttagttcata gatctgaact
     1321 ttatcttcat aactcaattt cataataaaa caccccaaaa gttagattta ttctgtctaa
     1381 cttttggggt gcagttcatt ttgcgggatt ttttttggta gaaacagttg cctgattaag
     1441 ttgcaagtcg atagacggct tcggcataaa tatccatagc acggtacaaa tcttctagaa
     1501 cggcacattc atttgcctga tgttctgtct gcttcgctcc tgggaataag gcgccgaagg
     1561 ctacacaatt tggcatggtg cgagcaaaag tggcaccacc ggatgaaata gcaggactgt
     1621 tatcgccagt cttttcttgg tagatttgca tcagtgtgct aacgagttta ctgtcttttg
     1681 cgacgtatag agacgctaga tagtcaaact cttcgtagcg gagttggtag ttttgtgcac
     1741 atcttgtaag caactctact agttcttcct tatcagttaa gacaggagtc cgaatgtcaa
     1801 tacggatttc agaacgttca tgattgatca tgagacctgc gacattaaag gataggtgac
     1861 cagaaggttc atctgctata tcaccaaaga tttgtcttcc tgtgccgtct tgacctgctt
     1921 gtgttgcaag aaagctgaga gcagggtgtt cttggagagg agcaagaatg gtagctagtc
     1981 ggatgacagc attgatacct tgactagcat ccttagcatg ctttggcact ccgagaaccg
     2041 ttacggtttg ttcagtggat tggtaatcat aaccagcttc tttgagatcg ttacaaacct
     2101 gttcatagag gggaccttgg tagttggcct tgtctggtac aacgttaaag gcgcctccta
     2161 cttcaagctc tagttgatcc gatccagggc catgaagttt gacctgtaga agcccttttt
     2221 cagcataggt cagaggaaaa gatgagtcag gtgcaaagcc catgctggcc tgttcttcga
     2281 tggtattgta gcgtgccatg cagcgccaga gggtttcctc atcggtacca aagataaagc
     2341 gtacgcgctt tttgaactga ataccttggt ccagcaagct ttttactgca tagagagctg
     2401 cgagcgaagg gcctttatca tcttggacac cacgtccgaa tacccagccg tctttgatag
     2461 ttgcttcaaa tggcggtgtc tgccaatctg cttcatcacc tgatggaaca acatccaaat
     2521 gacagagaat ggccagaagc tctgctccct gaccgatttc tgcatatccg taataacctt
     2581 tagggtcaag ataggtagtg aaacctatgt ctcgacaaat ctctaaagtt ttttctagga
     2641 catcttggat tgcttgtcca aaaggtgttc cattttctcc ttcattgagt actgaaggat
     2701 aggaaatcaa ggtttttaat gatataagaa attcatcttt aacttgattt gttatatcta
     2761 ttttcatgga atcacctcac tcactatttt ataggaatgg aaggaaggtt ccaaggagaa
     2821 gaagggcgat ggtcactaca ataatagcga ctacgagttt gcccatgaat ttccaccaag
     2881 taccaatgtt gatacgtcca agtgcaagag ctcccatcac aataccagat gttggtgcaa
     2941 tcaagttcaa gacacctgaa gcagattggt aagcagtgat aatcaagcta ggacggacat
     3001 ttacaaattc tccaagtgga gccatgatac ccatagttgc gctggcaaga ccagatgaag
     3061 atgggatcaa gaatgacata ggtagataga agatataagt tacaacgata aagacttgtg
     3121 aagatagacc gctcaagcct tctttacccc agttgaggat tgtatcggta atcataccgt
     3181 cgttcatgat aacttgaata ccacgagcaa tcgctacgat caaggcaaca ctgagcaagt
     3241 cagcagcacc attcatgaag gaagagataa tcttatcttc tttaagacca taaataacac
     3301 caatcaggat acccataaag gcaaagagca ttgcgccttc tgggaagtac caagtaccta
     3361 gtgcagaagt agatgaaccg acaatattac caataactgg aagaccagtc aaccaagcat
     3421 taaagtcatc aaaaatggta acgccaaggt ctgtccatgg aatgaagctc aataccatca
     3481 agatgaatgt caacacaaat aagaagagaa ctgatttttg tttgctgcta agtgtagatt
     3541 ctacagatga agattcttct acgttaaagt gtttcaaatc ttctttgcga gtactataaa
     3601 ccagtgactt agtcggatct ttttgaatct tatccgcata acggtaaaca aaccaagtac
     3661 taagagcagt caaggtaacc cagaagatca gacgaagtac gataccgtcc cctgtaccaa
     3721 ctcccgcagt cgctgaagca atacctgtcg caaatggatt cagagtagat gctaaacagc
     3781 cgatttgaga accgagcaaa ataattgcaa caccagtcag gctatcaaaa ccaacggcca
     3841 tcataactgg cacaaggagt ggatagaagg ccattgtttc ttcacccata ccataagttg
     3901 taccaccgag ggcaaacaaa ggcatcagta ccaaaattaa cattttttcg cggcccttat
     3961 acttcttcac gatagaggca atccctacgt caagagcacc agttttgttg acaatgccaa
     4021 ggaaaccacc aaccataagg atgaagaagg ctacatcaat cgctgcgctc gtttctttaa
     4081 tgagcgaacc ttcctctgga tgagtaccta gcatagcccg aatcggtgcc atgaggacat
     4141 cccaaatccc ttgtggattt tgaggctgag tctcgtaaat accttctata aaggcccccg
     4201 cagggataaa ccaagttagc actgccataa tagcaatgat tatcaataat acggtgtaag
     4261 atgaaggcat cttaaaccct tttttagctt tttcactcat ttgtttttcc tcctgatgtc
     4321 taacaaagtg taaaaaacca actactttct taaataaaca ttcaagaaaa cgctttctat
     4381 ttatatttgt tttaccatat taaagtctaa aactagtatc ttttgaaata ttgtacatgt
     4441 tttcaagaat aatttctaat ttgatataaa gatactagaa atagaataca tcttattagt
     4501 aaaacaactt atcctttttc aataattgtt ccgctttcag attcaatcaa ggcgcctaga
     4561 ttttcaaggg aagtaataac tgcttttcct tctggacgac cattgacaaa agcgatagct
     4621 gcttctactt ttggaagcat gctacctggt gcaaactgat cttgtttgat atattcttcc
     4681 agctgggcaa cattcacatg ttccaatttt tcctggtttg gcttgttgta gttaacaaat
     4741 acataatcta cacctgtcaa aacgatgaag aggtctgcat caaccaattc tgccaaacgt
     4801 tgggaagcga agtctttatc aataaccgct tcgacaccag tcaaatgtcc attgttttct
     4861 ttgacgacgg gaataccgcc accacctgca gctacgacga cttgaccatt atttaaaaga
     4921 gtacggatgg tttcaatttc tttgatgtca acaggttttg gtgaggcaac gaccttacgc
     4981 cagccacggc cagcatcttc cttgaaagtc gctccgctct tttcggcttc tgcttttgct
     5041 tcttcttctg aatagaaagg accgattggt ttactcaagt taacaaaagc tggatcattt
     5101 ttatctacga caacttgcgt tacaacagag gcaacatttt tttcgatgcc ttcatccaag
     5161 agagcatttt gcaaagcatt tttcaaccag aaaccgatgc taccttctgt catagcgaca
     5221 agtgagtcga gtgggaaggc agggttcttt tcagagtctg atgccaaatg ttggagcaag
     5281 agattcccaa cttgaggtcc attaccgtga gtgataatca gatcatctcc atttttaatc
     5341 aattttacaa gatgcttagc tgtttcaact aaagcttctt gttgagcctt tgctgatggg
     5401 tcagaagaaa gaatcgcatt tcctcccaaa gctactacaa ttttacgatt tgccataaat
     5461 tctcctttat cacactcaat agaatgcgtt tagatttcaa tttaatgatt tttcacatat
     5521 tttataagaa ataatagatt accattatat aaaagaggac cggactaaag ctattagtcg
     5581 cagccctcat agctgttggt agacggttta ttatctaaaa ttatacttta ggaatataaa
     5641 ggttaccaag tgtagcagcc ataacagctt tgatagtgtg catacggttt tctgcttgat
     5701 cgaagtggcg agcgtacttg ctgcggaaga cttcgtctgt tacttccatt tcttctacac
     5761 caaatttttc agcaacgtct ttaccataaa cagtgtgagt atcgtggaat gctggcaagc
     5821 agtgtaggaa gatcaagttt tcattgcctg cttttttaac taagtccata ttgacttggt
     5881 aaggtttaag aagagctaca cgttctgcga atttgtcttc ttcacccatt gatacccaaa
     5941 cgtctgtgta aagaacgtct gcatctttaa ctgcttcatc agcatcttca gtgatgagaa
     6001 catgtgcgcc actttcttta gcaaatcctt ctgctaattc aacgatttct ttttctggga
     6061 agagttcttt tggtgagaag atgtgaacat tgacaccaag gatagcacct gttacgagca
     6121 agctgttggc aacgttgtta cgtccatcac cacagtatac caatgtcaag ccttccaagc
     6181 gaccgaagtt ttcttgaaca gtcaagtagt cagcgagcat ttgagttggg tgccattcgt
     6241 cagttagacc gttccatact ggaacgcctg agaattctgc caattcttca accatacgtt
     6301 ggctgaatcc gcggaattca atcccgtcaa acatacgtcc caatacttta gcagtatctt
     6361 cagtagattc ttttttaccc aactgaatat catttgctcc gaggtattct gggtgagcac
     6421 caaggtcgat agccgcagtt gtaaaggctg cacgagtacg agtagatgtt ttttcaaata
     6481 ggagagcgat attcttgcca gcaaggtagt ggtgttgaat attgcgtttt ttcaaatctt
     6541 tcaagtgagc tgaaagacca ataaggtatt ctaactctgc acgggtaaag tctttttctg
     6601 ctaagaagct gcgtccttgg aatactgaat ttgtcatttt attatttcct ctttctattt
     6661 tttacatttt ctattgacga atgccgaaca gcgattacac ttcttcacgt tcaaatggca
     6721 tagacataca acgaggtcca ccacggcccc gaaccaattc acttccgcga atcttaatca
     6781 agcgaagccc gtattcttcc aaaatcttat tggtcacggt attgcggtca taaacaacta
     6841 ccacaccagg tgcgatggtc aaagtgttag aaccgtcgtt ccattgttca cgcgcagctg
     6901 ctacgatatt gccaccaccg caacgaatca aatgaacttt ttctacacca aggttttgag
     6961 caagaagttc agctaagtca cctttctctt caacgatttt aagtttttcg ttttcgtaag
     7021 taactgagta aacgtgaagg tcgccttcga tttctgggtg aatagtgaac ttgtcatagt
     7081 ctaccatagt gaagacagta tccaagtgca tgaatttacg gttgttagca aattcaaagg
     7141 ccaaaacttt cttgaagcca acatttttct tgaagatgtt gaccaaaagt ttttcgatag
     7201 aagctgcgtc tgtacgttga gagataccta ctgcaaggac gtctttagaa agaactaact
     7261 cgtctccacc ttcgatacgc gtatcttctt cacggttgta gaccaaatcc acttttccgc
     7321 catagattgg gtggtatttg aagatatact taccgtagag tgtttcacgg ttacgagtgt
     7381 ctgcaaacat gtggttaagc gatacggcgt ttccaattgt tgcaaatggg tcgcgagtga
     7441 aatagaggtt tggcatcggg tcaattgcaa atggataatc tgattcaact aagtcagtta
     7501 gatctttagc ttcgtcagga atttctggca attcaacttt ttgaatccca gccattgttt
     7561 tttcaaccaa ttcttggttg tccttgatgc cgtgaagcaa ttcacgaata gcaaccttgg
     7621 tttgacgatc acggatgttg gcttcgtcta agtattcctc gataaattga tcgcggattt
     7681 ctggagaggt caatgattca gcagcgagtt gttctaggta gagaacctca attccttcat
     7741 cgcgaagagc ttgggcaaat gcatcatgtt ctttttgagc atcttccaag aaaggaatat
     7801 catcaaaaag aagcctttca agatagtccg gcaacaagtt ttctaactcc ttgcctggac
     7861 ggtgcaacat aacttttttc agtttcccaa tttctgagaa gacctgaatt ggatgtgaag
     7921 acatgtattt tcctccttaa aaattttgac ttggcaccat tttgggtacc gcttacatgt
     7981 atgttataac gcaattccta ggtaatgtca atggctataa tttctcggaa aataatataa
     8041 attatgatgt ttagcacaat tttatgttat tatacataac ataggataga atacatagat
     8101 acaaatgcat aaacttctat taaagaggat ataaaatttt tttaaaaaat ttttcaaaaa
     8161 atacacaaat aaccaaaaag tgtccaatta tcatctggtt atcacttgga tctgtataaa
     8221 gagaaatgtt tgtgtgaaag gataaaaaga tgcaacattc ttttgaagat agattttgga
     8281 gaagcatttc ttgttcaatt gtacaaatta tagaatcttt tctgagtatt taggaagaga
     8341 taattatctt attgaccctc tttttatttt ttgttatagt cgacgagatg atagtttaga
     8401 ataatcactt attcacaatc tgtggaaaag tctggagagt gaatggtctt cacacaatga
     8461 cctgaaagaa gcctgagaat aattatggag agtagcattc tgagaggtgt tagcagaacc
     8521 atatgacaga gctgtttgaa gagggaatat tgaggagaaa aatcctgagc ctaccagttg
     8581 gagttggaaa gagctggcgg ttagatcatt ttttattatc cacaacctgt ggataacctt
     8641 gtgaacaaga gaagttgcta aagaaggaga tatataacga tgaagaaaat caaaccgcat
     8701 ggaccgttac caagtcagac tcagctagct tatctgggag atgaactagc agcttttatc
     8761 cacttcggtc ctaatacctt ttatgaccaa gaatggggga ctggacagga ggatcctgag
     8821 cgctttaacc cgagtcagtt ggatgcgcgt gagtgggttc gtgtgctcaa ggaaacgggc
     8881 ttcaaaaagt tgattttggt ggtcaagcac cacgatggct ttgtccttta tccgacagct
     8941 cacacagatt attcggttaa ggtcagtcct tggaggagag gaaagggcga cttgctcctt
     9001 gaagtatccc aagctgccac agagtttgat atggatatgg gggtctacct gtcaccgtgg
     9061 gatgcccata gtcccctcta tcatgtggac cgagaagcgg actacaatgc ctattatctg
     9121 gctcagctga aggaaatctt atcaaatcct gcctatggaa atggagggaa atttgctgag
     9181 gtttggatgg atggtgccag aggagagggc gcgcaaaagg ttaattatga atttgaaaaa
     9241 tggtttgaaa ccattcgtga cctgcagggc aattgcttga ttttttcaac agaaggcacc
     9301 agtatccgat ggattggcaa tgaacgaggg tatgcaggtg atccactgtg gcaaaaggtg
     9361 aatcctgata aactaggaac agaagcagag ctggactatc ttcagcacgg ggatccctcg
     9421 ggcacgattt tttcaatcgg agaggcagat gtttccatcc gtccaggctg gttctaccat
     9481 gaggatcagg atcctaagtc tctcgaggag ttggtcgaaa tctactttca ctcagtaggg
     9541 cgaggaactc cactcttgct taatattccg ccgaatcaag ctgggctctt tgatgcaaag
     9601 gatattgaac gactttatga atttgcgacc tatcgcaatg agctctataa agaagatttg
     9661 gctctgggag ctgaggtatc tggtccagct ctttccgcag actttgcttg tcgccatttg
     9721 acagacggcc ttgagaccag ctcttgggca agcgatgcag acttgcccat ccagttagaa
     9781 ctcgacttag gttctcctaa aacttttgat gtaattgagt tgagagaaga tttgaagtta
     9841 ggccaacgta tttctgcttt ccatgtgcaa gtagaggtgg atggtgtctg gcaggaattt
     9901 ggcaggggct tcacagttgg tcataagcgc ctcttgcgag gagcagttgt tgaagcacag
     9961 aagatacgtg tagtcattac agaatcacag gctttgcctt tgttgaccaa gatttcactc
    10021 tataaaactc cgaggttatc acaaacagta gctgttcagg ggctagcatt tgcagaaaaa
    10081 agcctagctg tggcaaaggg agagactctt cattttagga ttgaacgtag tgaaagtagc
    10141 tcctctttag aggctaagat ttcgattcaa ccggggacag gtgtccatgg tgtcgcctat
    10201 caggatgaga ttcaagtcct tcaattccaa gcaggggaaa gcaaaaaaga tttgcatcta
    10261 ccaaccctgt atttcgcagg agataaaacc ttggatttct atctgaacct aacggtggat
    10321 ggtcagcttg tggatcaact tcaagtccaa gtttcataaa agaagaacct ttgcgcgatg
    10381 caaaggttct tttggttatt agtgatttgg tagccagctg agggtgaaag ttagttgttc
    10441 agcttttagg aggtcttggt gttgaatagt tgatacgagt gttttgtcca gtcggcattc
    10501 tttgacaaag ttaaaatggc tgtggttttg ctcagtatga atatctagcc atttattttc
    10561 tttagctagg tagactcgta gatggtcaaa gagaggaatt ccgagatcat agcttggttt
    10621 tcctggacag gttggataaa atccgagagc tgaccagatg taccaagcag agagactacc
    10681 attgtcttca tctccaggat aggcttccca acttgggtga aaagctttct gacggagcgt
    10741 cttgataaga agggcagtgt agtcagggta atcgctgtag cggaagagat aaggaatgtg
    10801 gaaactaggc tggttggaaa tggctatttg tccaaaagga gcagtagcca tctcgctcat
    10861 ttcgtgaatt tcgtaaccat agcctgttgt ttcaaagagg ggagcatctt gacaggcttt
    10921 caaaagatag ttgctaaagg tttcttttcc acccatcagt tggattaagc cagggatgtc
    10981 gtggagaacg cctaaagtag cttgaatggc agagcattca gcgtagtctc gcccccaact
    11041 ataaggagag aagtcagggt gaaagtttcc ttgattgtct cgtgctcgca tgtaacctgt
    11101 ctcagcgtca aatagctggc ggtaattttg tgaagcagcc ttgtaggttt cagcgatttc
    11161 tatgtttttt agttttttgg cacagttggc gatacaaaag tcactatagg catagtctag
    11221 agtatggcta acactttcgt ggtggtcggt agagaggtaa cctagttctt ggtattgggc
    11281 tagtccgtgg cggccattga tgccgagagg gtcggctttg ctggctgttt tgagcatggc
    11341 ttggaagagt tctccttcta ggtcgggggc catgtccttg caggcgctat ctgcgataat
    11401 accgtctaaa agtgtacctg gcatcatacc ccgttcatct ggagccagcc attttggaag
    11461 gaaaccagta tcgcggtagc tattgaggaa accttctaaa aagcgttgat agtgctccgg
    11521 tatgataagg gcaaagaggg ggaaggtggt gcggaaggta tcccagaaac cattgttgct
    11581 aaagaggaca ccaggcttga cagtaccagt agccagatcc atgtggatgg cttgccctga
    11641 ctcatcaacc tcataaaaag tctgtgggaa gaggaagagt ctgtagagac agtggtcaaa
    11701 gaaggttcgg ttagcctctc ctgtctctat aacatcaaaa cgatggagga gattttccca
    11761 atccgcttgg gcacttgctt tacagctatc aaaatcttct tgaggtagat tgattagagc
    11821 ttgagaagga gagatgaaag aagtggctag ttgcatctcg gtttgactac ttgctaagtc
    11881 aattcgccag tctccagctt cttggctgat agcaagaata tccgtgttca tttgcagggc
    11941 agtgaacatc gttagcgaat ttttgttggt ttcagtttta ccttcttgtc gcagggcaag
    12001 agttcgctta tctacttgct ctactgtcag ttcatctgct gcgtgaagat agagggagag
    12061 ggctttgcct tgcttttgct tcaaacgaat agaagcaccg tagcaagtcg gtgtgagctg
    12121 ggtttcaatt tgatagcgca gggagaaaat ctttagataa tgaggttgga aagaggcctt
    12181 atccctatca taggaagatt ggcggtgaaa gagactgtct cccccaagct gacctgtgac
    12241 aggtgtcaga aggagccaag agtagtcccc aatccaagga ctgggctggt gagttaatcg
    12301 aatcccctga aagataggca gatgcggatc gaagaaccaa gatccatcct ggtcactggt
    12361 ctggggcaca aagtaattca tcccaaaagg cacgcctgtg tatggcaggg tatttccccg
    12421 agaaaaggca tgcttgttgg tagttcccaa gcgggtatcg atggtttcaa gtagtggttt
    12481 catagtcttt cctttagctg tttttctaca ttatatcaga aaaagagggc ctttagaaaa
    12541 ggagtttcaa agataactat tttgtagaaa aatgactatc atttgtgtat gtattttctg
    12601 tctcaaaagc tatatactga aaatgaaact tgtttgaaag agggaattgc acgatgattt
    12661 attcgaaaga aattgttaga gaatggctag atgaagtagc agagcgggct aaggaccatc
    12721 cagagtgggt ggatgttttc gagcgttgct acaccgatac cttggacaat acggttgaaa
    12781 tcttagaaga tggttcaact tttgtcttga ctggggatat tcctgccatg tggcttcgag
    12841 attcgacagc ccaactcaga ccctaccttc atgtagctaa aagagatgcc ctcctgcgtc
    12901 agaccattgc aggtttggtc aaacgtcaga tgaccttggt actcaaggat ccctatgcta
    12961 actccttcaa cattgagaag aactggaaag ggcaccacga gactgaccac acagacctta
    13021 acggctggat ctgggagcgc aagtatgagg tggattcact ttgctatcct ttgcagttgg
    13081 cttatctcct ctggaaagag actggcgaga ctggtcagtt tgatgagact tttgtcgcag
    13141 cgactaagga aattctccat ctatggacag ttgaacaaga ccacaagaac tctccttatc
    13201 gttttgtccg agatacggac cgtaaggaag acaccttggt aaatgatggc tttggacctg
    13261 actttgcagt gacaggtatg acttggtcag cttttcgtcc gagtgacgat tgctgtcagt
    13321 atagttactt gattccgtct aatatgtttg ccgtagtagt cttgggttat gtgcaagaaa
    13381 tctttgtcga attagaccta gctgatagcc agagtgttat tgctgatgcc aagcgtcttc
    13441 aggatgaaat ccaagaagga atcgaaaact acgcttacac caccaacagc aagggcgaaa
    13501 agatttacgc ttttgaagta gatggcctag gaaatgccag catcatggat gatccaaatg
    13561 taccaagtct actagctgcg ccctatctgg gctactgttc gatcgatgat gaagtgtatc
    13621 aagccactcg ccgtaccatt ctgagctctg aaaatccata cttctaccaa ggagaatacg
    13681 ctagcggtct cggaagttct cataccttct atcgctatat ctggccaatc gccctttcta
    13741 tccaaggatt gacaacaaga gataaggcag agaaaaaatt cttgctggat cagctggttg
    13801 cctgcgatgg tggtacaggt gtcatgcacg aaagcttcca cgtagatgat ccgaccctct
    13861 actctcgtga atggttctcc tgggctaaca tgatgttctg tgagttggtc ttggattact
    13921 tggatattcg ctaaggggct cgctttagct caaccgattc ttatcagaat cacaagttta
    13981 catttaaaac gttaaaattt aaatttagaa tgaggtttta cttcatggaa aatgttgttg
    14041 tacatattat ctcacatagt cactgggacc gtgagtggta cttgcctttt gaaagccatc
    14101 gtatgcagtt ggtggaattg tttgacaatc tctttgatct ctttgaaaat gaccctgagt
    14161 tcaagagttt ccacttggat ggacaaacta ttgtccttga tgactactta caaattcgcc
    14221 ctgaaaatcg cgacaaggtc caacgctaca ttgacgaggg caaacttaaa attggtccct
    14281 tttacatctt gcaggatgac tacttgatct ccagtgaagc caatgtccgc aataccttga
    14341 ttggtcaaca agaagctgcc aaatggggta aatcaaccca gattggctac tttccagata
    14401 cctttggaaa tatgggacaa gcgcctcaaa ttcttcaaaa atcaggcatt cacgtggcgg
    14461 cctttggtcg tggtgtgaag ccgattggat ttgacaacca agtccttgaa gatgagcagt
    14521 ttacatccca gttttcagaa atgtactggc agggtgtgga tggtagtcgt gttttaggta
    14581 ttctctttgc caactggtac agtaatggga atgaaatccc agttgacaaa gatgaggcct
    14641 tgaccttctg gaaacaaaaa ttgtcagatg tgcgtgccta cgcttcgacc aaccaatggt
    14701 tgatgatgaa cggctgtgac caccagcctg tacagaaaaa tctgagcgaa gccattcgtg
    14761 tggcaaatga actcttcccg gatgtaatct ttgttcatag ttcttttgat gaatatgttc
    14821 aagctgtaga aggtgcgctt cctgaacact tatcaactgt tacaggcgag ttgaccagtc
    14881 aggaaacaga tggctggtac acacttgcca acacttcttc atcccgcatt tacctaaaac
    14941 aagccttcca agaaaatagc aacctcctag agcaagtggt agaacccttg actattatca
    15001 ctggtggaca caaccacaag gaccagttga cctatgcttg gaaaacactt ttgcagaatg
    15061 cgccacatga tagtatctgt ggctgtagcg tggacgaagt tcaccgcgag atggaaacgc
    15121 gttttgccaa ggtcaaccaa gtaggaaact ttgttaaaag taacttgctc aacgagtgga
    15181 agggtaaaat tgctacggat aaggctcaaa gtgactatct ctttactgtc attaacacag
    15241 gcttgcatga taaggtcgat actgtcagca cagtgattga tgtggcgact tgtgatttca
    15301 aggtattgca cccaacagaa ggctacaaaa agatggctgc tcttatcttg ccaagttacc
    15361 gtgtggagga cttggatggt catcctgtag aggctacaat cgaagacctc ggagctaatt
    15421 ttgagtatga tttaccaaaa gacaagttcc gccaagctcg tattgctcgt caagtgcgcg
    15481 tgaccattcc agttcaccta gcgccgcttt cttggacaac cttccaattg ctggaaggaa
    15541 aacaagaaca ccgtgagggt atttaccaaa acggagtgat tgatacacca ttcgtaacgg
    15601 tgagtgtgga tgacaacatc acagtctatg acaagacaac tcacgaagcc tatgaagact
    15661 ttatccgctt tgaagaccgt ggggacatcg gaaacgagta tatctatttc caaccaaaag
    15721 gaacagagcc aatctttgca gaacttaagg gccacgaggt cttggaaaac acagcttgct
    15781 atgctaaaat cttgctcaaa catgaattga ccgtgcctgt cagcgcggat gaaaagctag
    15841 aagaagagca acaaggtatc atcgagttta tgaagcgtga ggctggacgg tcagaagaat
    15901 tgacaaacat tcctctggaa actgagttga ctgtcttcgt tgacaatcca caaatccgct
    15961 tcaagactcg ctttactaac actgccaagg atcaccgtat ccgtctcttg gtcaagactc
    16021 ataacacgcg tccaagcaat gattctgaaa gtatctatga ggtggtgaca cgaccaaaca
    16081 aaccagctgc ttcatgggaa aatcctgaaa atcctcaaca ccaacaagct tttgtcagtc
    16141 tgtatgacga tgaaaaaggg gtgactgtat ccaataaggg attgaatgaa tacgaaatcc
    16201 ttggggataa caccattgcc gtgaccattt tgcgtgcatc aggtgagcta ggtgactggg
    16261 gctacttccc aacgccagaa gcacaatgct tgcgtgagtt tgaagtcgag tttgcacttg
    16321 aatgccacca agcccaagaa cgcttctcag cctatcgtcg tgccaaagcc ttgcagacac
    16381 cgtttaccag ccttcagctt gctagacagg aaggaagcgt ggttgcgact ggtagcctct
    16441 tgagccattc tgttctcagc ataccgcaag tttgtccaac agcctttaaa gtggcggaaa
    16501 atgaagaagg ctatgtcctc cgttactata atatgagtca agaaaatgtg cgcatatcag
    16561 aacatcaaca aaccattctt gacttacttg agcgaccata tccagttcat tcaggactat
    16621 tggctccaca agagattcgt acagaattca tcaaaaaaga agaaatttaa tttcaaaaag
    16681 taaacatcaa aagaaaggag gggcgaaaaa gtaagaacta actgctgatt cgcccctttt
    16741 tatggtaaaa acaatgacca ttgcaacgat tgatatcgga gggactggga ttaagtttgc
    16801 cagtctgact cctgatggga aaatactgta taagacaagt atttcaacgc ctgaaaactt
    16861 ggaggattta ctagcgtggc tagatcaacg cttgtcagaa caggattaca gtgggattgc
    16921 tatgagcgtt ccaggtgcgg tcaatcaaga gacaggtgtg attgatggct tcagtgcggt
    16981 gccctacatc catggctttt cttggtatga ggcgcttagc tcttatcagc tacctgtcca
    17041 tttagaaaat gatgccaact gcgttggact cagtgaacta ctagctcatc cagagcttga
    17101 aaatgcagcc tgtgtcgtga ttgggacagg gattggcgga gccatgatta tcaatggtag
    17161 acttcatcga ggtcgccacg gtctgggtgg agaatttggc tacatgacaa cccttgcccc
    17221 tgctgaaaaa cttaataact ggtcgcaact agcatcaact gggaatatgg tacgatacgt
    17281 gattgaaaaa tctggtcata ctgattggga cggtcgcaag atttaccaag aggccgcagc
    17341 tggtaatgct ctttgtcaag aagccattga gcgcatgaac cgcaatctga cgcaaggctt
    17401 gctcaatatc cagtatctga tcgatccaga tgtcatcagt ctgggtggct ctatcagtca
    17461 aaatccagat tttatccaag gtgttaagaa ggctgttgaa gactttgtcg atgcctacga
    17521 agaatacacg gtcgcaccag ttatccagac ctgcacctat cacgcagatg ccaatctcta
    17581 cggtgccctt gtcaactggc tacaggagga aaagcaatgg taagatttac aggacttagt
    17641 cccaaacaaa cgcaagctat tgaggtttta aaaggtcata tttctctacc agatgtggaa
    17701 gtggctgtca ctcagtctga ccaagcctct atctctatcg agggtgagga aggtcactat
    17761 caattgacct accgcaaacc tcaccaactt tatcgtgcct tatccttgtt ggtaacagtt
    17821 ctagcagaag ctgataaagt agagattgag gaacaagcag cttacgaaga tttggcttac
    17881 atggttgact gttctcgaaa tgcggtgctg aatgtggctt ctgccaagca gatgattgag
    17941 gtcttggctc tcatgggcta ctcaaccttt gagctttaca tggaagacac ttaccagatt
    18001 gaaggacagc cttactttgg ctatttccgt ggagcttatt cagcagagga gttgcaggaa
    18061 atcgaagcct atgcccaaca gtttgacatg acctttgtac catgcatcca gaccttggcc
    18121 cacttgtcgg cctttgtcaa atggggtgtc aaggaagtcc aggagctccg tgatgtagag
    18181 gacattcttc tcattggcga agaaaaggtt tatgacctga ttgatggcat gtttgccacg
    18241 ttgtctaaac tgaagactcg caaggtcaat atcgggatgg acgaagccca cttggttggt
    18301 ttgggacgct acctgatttt gaacggtgtt gtggatcgta gtctcctcat gtgccaacac
    18361 ttggagcgcg tgctggatat tgctgacaaa tatggtttcc actgccagat gtggagtgat
    18421 atgttcttca aactcatgtc agcggatggc cagtacgacc gtgatgtgga aattccagag
    18481 gaaactcgtg tctacctaga ccgtctcaaa gaccgtgtga ctctggttta ctgggattat
    18541 tatcaggata gcgaggaaaa atacaaccgt aatttccgca atcatcacaa gattagccat
    18601 gaccttgcat ttgcaggggg agcttggaag tggattggct ttacacctca caaccatttt
    18661 agccgtctag tgactatcga ggctaataaa gcctgccgtg ccaatcagat taaagaagtc
    18721 atcgtaactg gttggggaga caatggtggt gaaactgccc agttctctat cctaccaagc
    18781 ttgcaaatct gggcagaact cagctatcgc aatgacctag atagtttgtc tgcgcacttc
    18841 aagaccaata ctggtctaac ggttgaggat tttatgcaga ttgatcttgc caacctctta
    18901 ccagacctac caggcaatct cagcggtatc aatcccaacc gctatgtttt ttatcaggat
    18961 attctttgtc cgattcttga tcaacacatg acacctgaac aggacaaacc gcacttcgct
    19021 caggctgctg agacgcttgc taacattaaa gaaaaagctg gaaactatgc ttatctcttt
    19081 gaaactcagg cccagttgaa tgctatttta agtagcaaag tagatgtggg acgacgcatt
    19141 cgtcatgcct accaagcgga tgataaagaa agtttacaac aaatcgccag acaagaatta
    19201 ccagaactta gaagccaaat tgaagacttc catgccctct ttagccacca atggctgaaa
    19261 gaaaacaagg tctttggttt ggatacagtt gacatccgta tgggcggact cttgcaacgc
    19321 atcaaacgag cagaaagccg tatcgaggtt tatctggctg gtcagcttga ccgcatcgac
    19381 gagctggaag ttgaaatcct accatttact gacttctacg cagacaagga cttcgcagca
    19441 actacagcta accagtggca taccattgcg acagcgtcga cgatttatac gacttaatac
    19501 tcttcgaaaa tctcttcaaa ccacgtcagc ttccatctac aacctcaaaa cagtgttttg
    19561 agcagcctgc agctagcttc ctagtttgct ctttgatttt cattgagtat aaaaacaaga
    19621 acaccttgct tggcgcaggg tgtttcgcgt gaaacagaag aattatctgg tttcaaatgc
    19681 tacagttaga caaacttatg ataaaatagc agaaagtgaa tgtttcctaa gagcaattct
    19741 atcgatgagc aattggaggt attatgctac acttaaaatt agtaaaacaa gaaatagaag
    19801 cttgggtcat ttccgtcaaa tttaaaaaag gttgctaccg acatatatag attccaaaaa
    19861 caaaaacgtt agcgaaacta gcagatgtga ttttatggag ttttgatttt gcaaatgatc
    19921 atgctcacgc atttttcatg gataatgttg agtggagtca tgcagattct tactttttta
    19981 gctttgttag tgacgatgtt gaagaacgtt acacagaaaa tgtctatctg gatagcctaa
    20041 gtgtcaaaca aaaatttaag tttattttcg acttcggtga tgaatggcgt tttgaatgcc
    20101 aagtgctgag agaaatcgag acagaggacg aagaagctta tctcgtacgt tcggttggaa
    20161 cgtcgccaga acaatatcca gattatgatg gttttgacta tgaagaatgg taaaattgaa
    20221 atcagtctgt gtaggcttag tatttcaata gacttcctgc aaaactagaa tcctagttca
    20281 tgattgataa taccagcact caaattcatt cgtaatccga agcgtttacg atgatttcga
    20341 taggttgttg aaattatttt aaacgttttt actttggcaa agatgttctc aaccttgctt
    20401 ctctccttgg atagcgcatg gttacaggct ttatcttcaa ctgttagcgg cttgagtttg
    20461 ctggatttac gtggagtttg tgcttgagga tatatcttca tgagcccttg ataaccactg
    20521 tcagccaaga ttttaccagc ttgtccgata tttctgcaac tcattttgaa caacttcata
    20581 tcatgacaat agttcacagt gatatccaaa gaaacaattc tcccttgact tgtgacaatc
    20641 gcttgagcct tcatagcgtg aaatttcttt ttaccagaat cattcgctaa ttgttttttt
    20701 agggcgattg atttttactt ccgtcgcatc aatcattacc gtgtcctcag aactgagagg
    20761 agttcttgaa accgtaaaac cactttgaac aagagttact tcaacccatt ggctccgacg
    20821 gataaagttg ctttcgtgaa taccaaaatc agccgcaatt tcttcataag ttcgatattc
    20881 tcgcactatt gaagagtggg cataagaagg tcttctaggc ttaatttagg ttttcgtcca
    20941 ccttttgcgt gtttaagttg ataagctgtt tttaatacag ctaacatctc ttcaaaagtc
    21001 gtgcgttgaa caccaacaag acgcttaaat cgtgcatcgg ttagttgttt acttgcttca
    21061 taattttgtt tcgcagggag tctattgact ctttggtagg tgtcaatgtt tttttcatct
    21121 atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt ttcccagaaa
    21181 gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc aaattttaag
    21241 tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa gttgagtgat
    21301 aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt aacccacttt
    21361 aatttctttt ttaacacggg ttaaaaaaaa aattaaagtg ggttaatttt ccttgactta
    21421 aaatttaaaa atgatatact gtgtttatgg agagatgaca atttataaaa tgtactactc
    21481 tattctacta gataatgatt gaataaaact ttttataaca acggctagca aagttataat
    21541 tttatatcta ttagaaaata aatatgtaag gaaatttaaa tgaaaaaaac tacaatatta
    21601 tcattaacta cagctgcggt tattttagca gcatatgtcc ctaatgaacc aatcctagca
    21661 gatactccta gttcggaagt aatcaaagag actaaagttg gaagtattat tcaacaaaat
    21721 aatatcaaat ataaggttct aactgtagaa ggtaacatag gaactgttca agtgggtaat
    21781 ggagttactc ctgtagagtt tgaagctggt caagatggaa aaccattcac gattcctaca
    21841 aaaatcacag taggtgataa agtatttacc gttactgaag tagctagtca agcttttagt
    21901 tattatccag atgaaacagg tagaattgtc tactatccta gctctattac tatcccatca
    21961 agcataaaaa aaatacaaaa aaaaggcttc catggaagta aagctaaaac tattattttt
    22021 gacaaaggca gtcagctgga gaaaattgaa gatagagctt ttgatttttc tgaattagaa
    22081 gagattgaat tgcctgcatc tctagaatat attggaacaa gtgcattttc ttttagtcaa
    22141 aaattgaaaa agctaacctt ttcctcaagt tcaaaattag aattaatatc acatgaggct
    22201 tttgctaatt tatcaaattt agagaaacta acattaccaa aatcggttaa aacattagga
    22261 agtaatctat ttagactcac tactagctta aaacatgttg atgttgaaga aggaaatgaa
    22321 tcgtttgcct cagttgatgg tgttttgttt tcaaaagata aaactcaatt aatttattat
    22381 ccaagtcaaa aaaatgacga aagttataaa acgcctaagg agacaaaaga acttgcatca
    22441 tattcgttta ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg tttagaaaaa
    22501 atcggtactt ttgcatttgc ggatgcgatt aaacttgaag aaattagctt ac
//
LOCUS       DAVIME010000030        22076 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVIME010000030 DAVIME010000000
VERSION     DAVIME010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22076
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.030"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(20..217)
                     /gene="blpI"
                     /locus_tag="VV588_001321"
     CDS             complement(20..217)
                     /gene="blpI"
                     /locus_tag="VV588_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEU7083659.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            498..2651
                     /gene="blpA"
                     /locus_tag="VV588_001322"
     CDS             498..2651
                     /gene="blpA"
                     /locus_tag="VV588_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEU7083660.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLVIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2662..4023
                     /locus_tag="VV588_001323"
     CDS             2662..4023
                     /locus_tag="VV588_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU7083661.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSIISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTSNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVASDYLPLLDKGQTVRLKLEKIGNHGITIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4080..4235
                     /gene="blpC"
                     /locus_tag="VV588_001324"
     CDS             4080..4235
                     /gene="blpC"
                     /locus_tag="VV588_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU7083662.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(4280..5620)
                     /locus_tag="VV588_001325"
     CDS             complement(4280..5620)
                     /locus_tag="VV588_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU7083663.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(5634..6371)
                     /locus_tag="VV588_001326"
     CDS             complement(5634..6371)
                     /locus_tag="VV588_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083664.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6376..6714)
                     /locus_tag="VV588_001327"
     CDS             complement(6376..6714)
                     /locus_tag="VV588_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083665.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            6990..7319
                     /locus_tag="VV588_001328"
     CDS             6990..7319
                     /locus_tag="VV588_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU7083666.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7487..8536)
                     /locus_tag="VV588_001329"
     CDS             complement(7487..8536)
                     /locus_tag="VV588_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083667.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8533..9264)
                     /locus_tag="VV588_001330"
     CDS             complement(8533..9264)
                     /locus_tag="VV588_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083668.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9332..9742
                     /locus_tag="VV588_001331"
     CDS             9332..9742
                     /locus_tag="VV588_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU7083669.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9752..10039
                     /locus_tag="VV588_001332"
     CDS             9752..10039
                     /locus_tag="VV588_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083670.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10405..11541)
                     /gene="dnaJ"
                     /locus_tag="VV588_001333"
     CDS             complement(10405..11541)
                     /gene="dnaJ"
                     /locus_tag="VV588_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU7083671.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(11746..12099)
                     /locus_tag="VV588_001334"
     CDS             complement(11746..12099)
                     /locus_tag="VV588_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083672.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(12112..13935)
                     /gene="dnaK"
                     /locus_tag="VV588_001335"
     CDS             complement(12112..13935)
                     /gene="dnaK"
                     /locus_tag="VV588_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU7083673.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14415..14939)
                     /gene="grpE"
                     /locus_tag="VV588_001336"
     CDS             complement(14415..14939)
                     /gene="grpE"
                     /locus_tag="VV588_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU7083674.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(14966..16000)
                     /gene="hrcA"
                     /locus_tag="VV588_001337"
     CDS             complement(14966..16000)
                     /gene="hrcA"
                     /locus_tag="VV588_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU7083675.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16164..16673)
                     /locus_tag="VV588_001338"
     CDS             complement(16164..16673)
                     /locus_tag="VV588_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU7083676.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            17280..19613
                     /locus_tag="VV588_001339"
     CDS             17280..19613
                     /locus_tag="VV588_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU7083677.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSCSTPGFVDKEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            19626..21089
                     /locus_tag="VV588_001340"
     CDS             19626..21089
                     /locus_tag="VV588_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU7083678.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21089..>22076
                     /locus_tag="VV588_001341"
     CDS             21089..>22076
                     /locus_tag="VV588_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU7083679.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT         7047 a         4455 c         4063 g         6511 t
ORIGIN      
        1 atatttaaga atcataatct tacaaagagg acataattcc tgaacctaca caaataagtg
       61 ttgctgctcc cccagttatc ggaccagtcg cagcagctaa tagtactgct ccaatacaac
      121 caccgattgc agatcctaaa ttgcctcttc ctccactaac tatttcgagt tcttcattat
      181 ccataacaga aaattgttcc atcatttttg tattcatgac aaatactcct tttttatttt
      241 taatttttgt cttgttgcaa ctttgacaag tttagtatat cattattttt taattttttt
      301 catccaaatc ttgaattgcc atcgaaacgt cttgaattag cttttttatt tcaagccacc
      361 tctaaatgtt taaaaaaaat aatttctaat cactttttta ccattcagga agttttaatg
      421 actattcaac atttcataaa atatgaactt agttttatgg cataatatac ctatccacta
      481 tatgaaagga attgccaatg acttcttata aacgtacatt tgttcctcaa atagatgcga
      541 gagactgtgg tgtcgctgcc ttagcctcga ttgctaaatt ctatggttca gatttttctc
      601 tagctcactt gagagaactt gcaaagacca ataaagaagg gacgactgct cttggcattg
      661 taaaagccgc tgatgaaatg ggctttgaaa caaggcctgt tcaagcagat aaaactctct
      721 ttgacatgag tgatgtcccc tatccattta tcgttcacgt taacaaagaa ggaaaactcc
      781 aacattacta tgttgtctat caaacaaaga aagactatct ggttattggt gatcctgacc
      841 cttctgtaaa aatcactaaa atgtcaaaag aacgcttttt ctctgaatgg actggagtag
      901 ctatttttct agctcccaaa cccagctatc aaccccataa agataaaaag aatggtctac
      961 taagcttcct tcctctgatt ttcaaacaaa aatctctcat tgcttacatt gttctctcaa
     1021 gcttattggt cactattatc aatataggtg gttcttatta tctccaagga atcttagatg
     1081 aatacatccc aaatcagatg aaatcaactt taggaatcat ctcagttggt ctggttatca
     1141 cctatatcct ccaacaagtc atgagcttct ccagagatta tctcctaacc gttctgagcc
     1201 agagattaag cattgatgtg attttatcct atattcgcca tatttttgaa cttcccatgt
     1261 ctttctttgc gacacgtcgt acaggagaaa tcatttcacg gttcacagat gctaactcta
     1321 ttatagatgc cttggcttct accattcttt ctcttttcct ggatgtttct attctgattc
     1381 ttgtaggggg cgtcttactg gcacaaaacc ctaatctctt ccttctttct cttatttcta
     1441 ttcctatata catgttcatc atcttttctt ttatgaagcc tttcgaaaaa atgaaccatg
     1501 atgtcatgca aagtaattct atggttagct ctgccattat cgaagatatc aacgggattg
     1561 aaactataaa gtcgctcacg agtgaagaaa atcgctatca aaatatagac agcgaatttg
     1621 tagattattt ggaaaaatcc tttaagctca gtaaatattc tattttacaa acaagtttaa
     1681 agcagggaac aaaattagtt ctgaatatcc ttatcctatg gtttggcgct caattagtca
     1741 tgtcgagtaa aatttctatc ggtcagctga ttacctttaa cacacttttt tcttacttta
     1801 caactcctat ggaaaatatt atcaacctcc aaaccaaact ccaatctgcg aaggtcgcta
     1861 ataaccgttt gaacgaagtc tatctagtcg aatctgaatt tcaagttcaa gaaaaccctg
     1921 ttcattcaca ttttttgatg ggcgatattg aatttgatga cctttcttat aagtatggtt
     1981 ttggacgaga taccttaaca gatattaatc tcacgattaa acaaggagat aaggttagcc
     2041 tagttggagt tagtggttct ggtaaaacaa ctttagccaa aatgattgtc aatttctttg
     2101 aaccctacaa agggcatatt tccatcaatc atcaggatat taaaaacatt gataaaaaag
     2161 tcttgcgccg tcatattaat tacctacccc aacaagccta tatctttaat ggctctattt
     2221 tggaaaactt aaccttgggc ggtaatcata tgattagtca agaagatatt ctaaaagctt
     2281 gtgaagtagc tgaaatccgt caagacattg aaagaatgcc tatgggctat caaactcagc
     2341 tctctgatgg agctggtcta tcaggaggac agaagcaacg aatcgctctc gctcgtgctc
     2401 ttttaactaa atctcctgtt ttaatactag atgaagctac tagcggtctt gatgtcttga
     2461 ctgagaaaaa agttatagat aatcttatgt ccctaactga taaaaccatt ctctttgtag
     2521 cccatcgtct cagtatagcc gaacgaacca accgtgtcat tgttcttgac caggggaaaa
     2581 tcattgaagt tggtagccac caagagttaa tgcaggcgca aggtttctac catcatctat
     2641 tcaataaata aggagaatgt catgaatcct aatcttttta gaagcgtcga gttttatcag
     2701 agacgttacc ataactatgc gacagtgtta attatacctc tttcattact atttactttc
     2761 atcttgattt tctcccttgt tgccacaaaa gaaattactg tcacttccca aggagaaatc
     2821 gcccctacaa gtatcatttc atctattcag tcaaccagtg ataatcctat ccttgctaat
     2881 catttagtgg caaatcaagt agttgaaaaa ggggacttac tcatcaaata ctctgaaaca
     2941 atggaagaaa gtcagaaaac tgccttagca actcaattac aaagacttga gaagcaaaaa
     3001 gaaggacttg gaattttgaa acaaagctta gaaaaagcga ctgatctttt ttctggcgag
     3061 gatgaatttg gctaccataa tacctttatg aattttacta aacaatccca tgatattgaa
     3121 ctgggtatca caaagactaa cactgaggtt tcaaatcaag ctaatcttgc caatagcagt
     3181 tcatcagcta ttgaacaaga aattacaaaa gttcaacaac aaattggaga atatcaagag
     3241 ctgagagatg ctatcataaa taacagagca cgcttaccaa ctagcaatcc acaccagtca
     3301 attttgaatc gttatcttgt agcctcacaa ggacaaacac aaggaacggc agaggagcca
     3361 tttttatctc aaattaatca aagtattgca ggtcttgaat catctatcgc aagcctcaaa
     3421 attcagcaag ctggtatcgg aagtgtagca acttatgata atagtttagc aaccaaaatt
     3481 gaagtactcc gcactcaatt tttacaaaca gcttctcagc aacaactaac cgtggagaac
     3541 caattaacag aattaaaagt acaactagat caagcgacac agcgcttaga aaacaatacc
     3601 ttaaccgctc caagtaaagg tatcgttcat ctgaacagcg aatttgaagg taaaaataga
     3661 attccaactg gtacagaaat tgctcaaata ttccctatca tcacagatac aagagaagta
     3721 ctaatcactt actacgtagc ttctgactat ctacctctac tagataaagg acaaactgta
     3781 agattaaaac tggagaagat tggaaatcac ggcattacca tcatcggcca acttcagaca
     3841 attgatcaaa ctcctaccag aacagagcaa ggcaatctct ttaaattaac cgctcttgca
     3901 aaactatcta atgaggatag taaactcatc caatatggct tacaaggtcg cgtcactagt
     3961 gtaactgcaa agaaaacata ttttgattat ttcaaagata aaattttaac ccattctgat
     4021 taattttcag ataacactct ataactattt attatcttat caaaaaggag aatcataaca
     4081 tggataagaa acaaaactta acttcatttc aagaactaac aactaccgaa ctcaaccaaa
     4141 ttacaggtgg aggactgtgg gaagatatct tatacagcct taatataatt aagcataaca
     4201 atacgaaagg acttcatcat ccaatacaac tataaaaaat aagaccgagt aacaagaact
     4261 ctcggtctta tttttttcat cattctgtag gtatcatagt aagcacctga cgaaagactt
     4321 gatcttgaca ggtagtattt aaactggcat tgggataact ttccacaatc ttcataacgg
     4381 tatagagacc gacacctctc tcctcccctt tagaactaac tccaaaggag aagatttcag
     4441 aaatatcgat gccctcttct ttgatggagt tttcaatgat aaaagtctcc tgtgctccac
     4501 tttttaaaaa ggcaattgaa acatgaggtt gaccggcctc tgcactcgct tcaatagcat
     4561 tatcacaaag gatagacaca atggttagaa aatcaagcag tctcatcccc tcaacctgaa
     4621 tctcttcagg aacttcgaca ttaaagacaa tgtccttttc tctagctttt ataaattttc
     4681 cagctaggag acttttgagg gcacgatccc gaacattcac caatctgccc aggtcatatt
     4741 tattgtcctg caatttctga ctggaatccc ttaagaccaa gtcatagacc tcttttatct
     4801 gctccatatc ctcctcttca atacccagac gtaaacttgt caagaggttg gtgtagtcat
     4861 ggcgaaaact ccttacttcc ttgtaaagtt cctctatatg ccgactatag cgttctatat
     4921 ctctatagcg caagacctgc tcttggtcca gtctatcatg gagtttgtcc ttcaaatagg
     4981 tatccaattt cttgataacc cccataaaaa ataggaggta aaacactaga atgagatggc
     5041 gaacagtcgt tgattgaata ccttgctcat attcaaagta agacagactt tgtatcacca
     5101 aatagtaagc ccccattatc cagttaatct tagtcaggga cttttgaaaa cctgtatcta
     5161 gaatctccct tctcaaacta gtaaaatcat agtccaacca tttcaaaaag gctagagaaa
     5221 tgaagaaatt gaaaattatt atacataacc cagtaaatga gtagccatca tatacttgct
     5281 cttgtcccaa aaatggaagc acaaaatagg agactcctct ataaaagaga ttcaccaata
     5341 tcattggaaa gagaccataa aagaaaagga gttttttagg aagccctctt aacaataaga
     5401 aagacaagcc tatgccgtac aagggttcca taaaataaga taggtaaaca tttcctacca
     5461 tatagccaat cattacaaaa acaaaggcca acagtatctt caaaagaaag gccttaaaaa
     5521 tcctctcaaa agtgagacca attccatcta ccttaaagaa aatgacaatt tttaatccgt
     5581 gagtaacaag tgtatacaac aatatccaag caacattcat aaactctcct agctcagtgt
     5641 aagttattaa tagcctcaga cacttccctg accttataac gcgcgatcag acagcttcca
     5701 ccattgggaa agaaaaggag tttttctttc ttatccaaat gcaccacatt tgcaggattg
     5761 atgagaaaag agcgatggca ctgcaagaga cggggttcct gcttaaaaac ctcctctaaa
     5821 ctcgccgtaa attctagcct gtccgtcttg gtatagagaa taacacgatg gggtcttggg
     5881 gatgtttcga gatagtaaac ctctttgaaa ggatattgga attgggcaaa ttttgattta
     5941 aagtaaaagc aatcttccgc cagactttta ctatcttgac tattggcata gaggagggct
     6001 gtctcgatac gagattcaaa ctcctctgcc gaaagggcct tatcaatgta gtccaaagct
     6061 gacacttggt agcgaaagga cagaggcata aactccgagt gagtcgtcac aaagacgatt
     6121 agggcataag ggtcttgttc ccgaatcttt ctagctactt ccagtccctt catctcttca
     6181 tttcgaatct caatatccaa aaagaatagc tgatgggccc ccttctcatg cacctctgcc
     6241 agcagttggt ccggcttgcc aaatacctca aaagagctag gaatgatatg atgtgctttc
     6301 aaaagtttct caatcgtcgt ttcaattcta gtctgttggg aaaaatcatc ttctaaaaca
     6361 aatattctca tcttcttact ctccctcttt caaccatttt tgacgtattt ctctatagcg
     6421 acgtctggca tacttgacag catattgacc ttcttctccg agaaaaagga ttctttcttg
     6481 aaaatcaatc gattttaatt tatcaagatt aaccaaacaa tttcgatgac atctcatcaa
     6541 agtttcccca cattggttct caagattact taaattttga agcatattaa aactagcttt
     6601 ttctgtaaca atctgtacgg tatgggcttt agttggatgt gtttggatat agtagatatc
     6661 gtcgatgttt actttataga ctgttttctg tgtctgaata atcatatgtt tcattggatt
     6721 ctcctcctaa gaaaagaata acagaaaagg tctagcccaa gcacacccaa tcctaaacag
     6781 tctttgaaaa ctcctaaaag gattattttc tacaacatca tgatgagctt acaactattt
     6841 tatcataaaa ttcactcagc gcaattcaag acatttcaat gacaattaaa gatttgaata
     6901 aaaaaaaaga attaaaagtg ataaactaac agtatcaaaa cacagttgcc agaagtaaga
     6961 ctggcaccca gattaaagga ggcattccca tgacagatac agaccccatc aaaagagctc
     7021 atactttgat tactgactta aacaaagcct accaagcatg caaacaggca agcgctgacg
     7081 acgtccgctt tcaggagcaa ttaaactcta ttcttggttt tctagccaag gctgaaacag
     7141 tggataatcg attcttgatt gaactagaaa aattttacca gacttccagt cttctcatgg
     7201 gactcagcgc tcttgatcca gatgctccaa ctcgcgccgc ttggcgggcc tatgaccgct
     7261 tccactttga ccaagtcaag accaagttaa tactcaatga gaatcaaaga gcaaactagg
     7321 aagctagccg caagctgtac ttgagtacgg taaggcgacg ctgacgtggt ttgaagagat
     7381 tttcgaagag tataagtctc tacggaccaa ccattatcct gtagtaacaa aaaagaagct
     7441 gagacagact gaactcaact tcttttttag tgtcgtatca gcaatgttag tcctgcatct
     7501 gacgttttac ctgataaggc aaatacaaga ctagtaaaac caaaccagct cctagtaagg
     7561 ctagaagggc cagtttttct tggaaggtaa tcaacccaac aactaattcc acaagtaaaa
     7621 caaaactggt caatcctcga actacctcct gcaagccttt ttccttttgc cccttgtcca
     7681 gcggaaagag ttgggtcaaa tactggtagt caaaggcatg atagagggcc agcaactgga
     7741 agagcaagag gtagttaaag agaactacca ctgctgtcgc aatccaagct tgctcgataa
     7801 aaacctgcgc cagtacggaa agtaatagaa gacgaagact gagagcaaag aggtcgccat
     7861 ttcgcagata agaacgcaga tagagatttt gccaaatctt cccaggcacc ttctgaacag
     7921 cctttaagat aaagtccaga taggcacgac gcttaacgct gtttgaaatt cccttgacct
     7981 gcgtaaagag ggcaaagaaa cgaagcaaga cttgcttacg cttgctttct tgagaaataa
     8041 catagtccca gtccagtcca gtttcagtga aaaatttgct ggccttttga cgaaagtgga
     8101 aatattttcc tacccccaat aaaagcacat agagcagaaa aactggcaag ccataaccca
     8161 ttgctaaaaa taaaggcgca aataacagca agaaaagggt ctgtacaaag agccaaaaga
     8221 ctagggaaat gccagtttga cgcttgagat ggagcttgat ttcctcttct ccaactaaga
     8281 gaaagagctt gtctggagcc tccatatagg tggcaattcc tccccaaagt aaaagtaaaa
     8341 cagacgtaat tcctacaaac aaaaggatag gccaatgatt ttcaggaaaa tgttgtaaga
     8401 gttgactgta ctggtaggct agaaagccca acaggacaag caggaacaag acaaagtggt
     8461 cattgagcac atagcgcaga taaccaagac actccttacg aaaggcctgc tttctcttta
     8521 aaaacaagtc tttcataggt cctcctcttt tgtcagagcc aagtaaatat cattcaaact
     8581 agcctcaggc atatcaaagg cttcgcgtag ttgcaggaga ttgcctttgg cacgcacctc
     8641 tcccttgtga agaatgacaa aggcatcaca catcttctcc gccgaatcca gcacgtgggt
     8701 actcatgaga atagacttgc ccttttgctt ctccacttcc aaaagctgaa tcaaatcaga
     8761 aatagccagc ggatcaagac caaggaaagg ctcatccacg atgaaaagac ttggatccac
     8821 cacaaaagca cagataatca tgaccttctg cttcatccct tttgaaaaat gaacagggaa
     8881 ccagtctaat ttctgttcca aacggaacat ttttaacaag ggctctactc gttcgaaagc
     8941 cactttttgc tcaataccgt aagccatagc aaccgtttcg atatgctctc tgagggtcaa
     9001 ttcctcatac agactaggcg tctcaggaat gtagccaatc tgcttgcggt agctagtcgc
     9061 atctccttgc agagtcaggc cattgatatt gatggagcca ctataaggtg ccaacagacc
     9121 gataatctca ttgatcgtcg ttgatttccc agcaccattg agaccaatca aaccgaccaa
     9181 ctgcccactt tcaacagtaa aggacacatc tttcaaaaca ggaacatgaa catagccacc
     9241 tgtcaggttt ttaatttcta acatattttc tccaaatctg gtataatgta gctatattat
     9301 atcaaaattc agtacagtag aggtagattt tatgtcagat tgcatttttt gtaaaatcat
     9361 cgcaggggaa attcctgctt caaaagtata tgaagatgag caggtccttg cctttcttga
     9421 tatctctcaa gtaacactag gacacacctt ggtcgtgcca aaagaacact atcgcaatct
     9481 tttggagatg aatgctacga gcgccagcca actctttgcc caagtaccaa aagtagctca
     9541 aaaagtcatg aaagtcacta aggctgctgg tatgaatatc atttccaact gtgaagaagt
     9601 cgctggtcaa acagtttttc atactcacgt tcaccttgtg cctcgctaca gtgctgacga
     9661 tgacctcaag attgatttta tcgcccacga accagacttt gacaaacttg ctcaagtcgc
     9721 tgaaaccatc aaaaacgctt aaggagttgc tatgaaatta tccaacctac tgctatttgc
     9781 aggagctgca gccggaagtt atctggttac aaaaaatcgc caaaccatca cagatgaagt
     9841 cttaaatacc actgaccgcg ttcaagctat caaagacgat gtggatatta tccaaaatag
     9901 cctgcaaatc atcgaccagc aaaaagaact tatcaaggaa taccaagaag acttgactta
     9961 caagtttaag gtcttggaaa aggatatcca gactagacta gctgtgataa aagaaatgca
    10021 gggaactgaa gataagtaaa aagagccccc ggctcttttt taaaacgtaa acaagttata
    10081 gtgaattgaa tttagaatag cacatcatag tttctaaagc attgttagag attactttaa
    10141 aatcctctta tcaatttgtt catattctat ttcaatctac tatatatatc ccatcaacta
    10201 tgcatcataa tttaggtaac tcatactcaa taaaaatcaa aaagcaaact agaaagctag
    10261 gcacagactg ctcaaaacac cgttttaagg ttgtggatag aactgacgaa gtcagctcaa
    10321 aacactgttt tgaggttgta gatacgactc acatatatac ggcaagccga cgctgacgtg
    10381 gtttgaagag attttcgaag agtattattc tccatcaaag gcatctttaa tatggtcaaa
    10441 gaagcctttt ttctttggat ttactttcaa gtcaccagca gccgcgaatt ctttcaaggc
    10501 tactttttgg cggtcgttca agcctgtcgg tgttacgaca ttaacagtaa cgtattggtc
    10561 accaactgca ccgccacgaa ggctcggtgc ccccttacta cgtaggcgga atttcttacc
    10621 agtctgagtt ccctctggaa taaccaattc aacatcaccg tgaacagttg gaatatctac
    10681 tgtatcacca agagccgctt ggacaaagtt gaggttgaga ttgtagaaga tagtcgttcc
    10741 ttcacgttca aacttgtcgc tagcttctac agaaactact acatacaagt caccataagg
    10801 tccaccgtta aagcctgctt caccttgacc agcgaggcga atttgttgac ctgtttccac
    10861 accagcaggg attttcacat gtacgctatg agcttgtttc tcatgacctg ttccatgaca
    10921 ggttgtacat ggatatttga tttcttttcc tcgaccgtga cagacatcac aggttacttg
    10981 gcgacgcatc ataccaagag gagtctgcgt atcgacgtta atgacaccag cgccatgaca
    11041 gcgtccacaa gtgactggac ttgtccctgg cttagcacca gagccattac atgtacgaca
    11101 gccagcttca cgatgatact taacttcctt ctcagttccg aagatagctt cttcaaaggt
    11161 caaattgaca cgatactgga gatcatctcc ttggcgagga gcgtttggat tgcgcgaaga
    11221 accgcctccg ccgaagaaac ttgagaaaat atcctcaaaa ccaccgaagc cacctgcccc
    11281 attgaaaccg ccgaaaccac cagctccacc aaaaccacca ttggcgcctg cagcaccata
    11341 ctggtcatag gcagcacgtt tttggtcgtc actcaaagtc tcataggctt cttgaacttc
    11401 cttgtacttg tcctcagcac caggctcctt gttgatatct gggtgatatt ttttggaaag
    11461 cttacgataa gcctttttga tctcgtctgc cgaagcgttt tttgacaccc ccagacgatc
    11521 ataaaattca gtattgttca tacaagatac caagaccgta aaattcgact gaaaaatagg
    11581 aaatctgacg ctggagcgac gctcctagac agatttctct tttttccgag aatttaggtc
    11641 gggttcaatt cctttctttt atattgatga gataatactc cagccactcg gccctatccc
    11701 tttttaccga aaaacagagg ctgggttgca acctctgtgg ttagattatt catttgaaat
    11761 aaaaatggtt gtattatctc tagtagtaat cttcaaagac cttttagcta aatcaaactc
    11821 aaatttatta tagtgtgggt cttgtgtttt atataggtgt aactcctgac atatatgatc
    11881 cgaaaagtaa atcataacat ctttaaacac agaagtgtag tcatatttac tcttaccaac
    11941 agctacttct gtaaattctt tataaatgac atttccattt ctttccacag tcaccagcat
    12001 ttctgttgga ttataatcca aattaaataa ttcttcaaaa aactttatct tttcatgata
    12061 atctgcaatg tcagaaagat tatttttatt aacactcata acactagccc cttacttttc
    12121 cgtaaactct ccgtctacga cgtcatcgcc tgcgtttcct gttgcttgtg cgccttctgc
    12181 tccttcttga gcttgttgcg ctgctgcggc ttgttcgtag agtttaacag caagtccttg
    12241 agctttttcg ttcaatgctt caagttttgc tttcatgtcg tccaagttgt tgtcttcttg
    12301 agctttctta aggtcatcaa gggcagcttg ggcagcgtca cgttctgcgt cgaagccttt
    12361 accttcagtt tccttgattg tcttttcagt cgcaaagatt gcttggtcta cttcattacg
    12421 aaggtctact tcttctttac gtttcttatc ggcttcagcg tttgcttctg catctttcat
    12481 catgcggtcg atttcttcgt cagtcaaacc tgagttcgat tggatgacaa tagtttgttc
    12541 tttttgagtt ccaaggtctt tggccttaac agacacgata ccgttcttgt cgatatcaaa
    12601 tgttacttcg atttgaggaa ttccacgagg tgcagctggg atatcagtca attggaagcg
    12661 tccaagagtc ttgttatctg ctgccattgg gcgttcacct tgaagaacgt ggatatcaac
    12721 ggctggttgg ttgtctgctg ctgttgagaa gacttgtgat ttagatgttg ggattgtagt
    12781 gttgcgatcg ataagttttg taaatactcc acccattgtt tcgataccaa gtgacaatgg
    12841 cgttacatca agaaggacaa catccttgac atcaccagta atcacaccac cttggatagc
    12901 cgcacccata gcaactactt catcagggtt tactgatttg tttggttctt taccagtttc
    12961 agctttaaca gcttcaacaa cggcagggat acgagttgaa ccaccaacaa ggataacttc
    13021 gtcgatttct gacaagctca aacctgcatc tgaaagggct tgacgaactg gaacttttgt
    13081 acgttcaaca aggtcacgag tcaaatcatc aaatttcgca cgagttaaag tcatttccaa
    13141 gtgaagaggt ccagcctcac ctgcagtgat aaatggcaag ctgatttgtg ttgaagttac
    13201 accagaaagg tctttcttcg ctttttcagc cgcatctttc aaacgttgca ttgccatctt
    13261 gtcagtagac aagtcgatac cgttttcttt cttgaattct gctaccaagt ggtcaatgat
    13321 tttttggtca aagtcgtcac caccaagttt gttgtcccct gcagttgaca atacgtcgaa
    13381 gacaccgtca cccaattcaa ggatagagac gtcgaatgta ccaccaccaa ggtcaaatac
    13441 caagattttt tcttctttgt cagtcttgtc caaaccataa gcaagagctg ctgcagttgg
    13501 ttcgttaaca atacgttcta cttcaagacc agcaatttta ccagcgtctt ttgttgcttg
    13561 acgttgagcg tcgttgaagt aagccggaac tgtgataaca gctttggtta ctttctcacc
    13621 aaggtagtct tcagcgtagc ctttcaagta ttgaaggatc atagctgaga tttcttgtgg
    13681 agtgtattct tttccatttg cagaaacttt ttcagaagtt cccatcttag atttgataga
    13741 gataactgta tctgggtttg tgactgcttg acgttttgca gcatcaccaa cgatgatttc
    13801 tccgtttttg aatgagacta cagatggagt tgtgcggttt ccttctgggt ttgcgatgat
    13861 tttgctttca gttccttcaa gaactgcaac tgctgagttt gttgtaccta agtcaatacc
    13921 gataatttta gacatgtgtt tttctccttg ttagttaatt ttctattttt ctttttgata
    13981 ctcttcttaa gtggcgacgc cgtcagagct tgacttcgtc aatctctttg actaaacttt
    14041 gagcctaagg tctcaaaatt tgcgcaaata gcgccacggc gaagagtatc gtgtttggtt
    14101 cgcttcgctc actattacaa agccaaacat attttatctt tcttcatagt ttattgtcgt
    14161 ttcggacaag ttttctatta tgtaaattgc gacacgaaga gtcgaaatcg attttatttc
    14221 gacgacgagt tagtaaggaa gctaggcaaa cgccatagcg attgccgttt tctgacgagt
    14281 tgctttagct accgtcagaa ttgccgaatc gaacacgccc taagctctga gtaaaaaaga
    14341 tagattttct tgtgttcatc gaacacttcg tcaatctcct atttttactg cgagcttttt
    14401 acgggctttg tatcttagtt atacaccact accattgctg ggcgtaggat gcggtcatgg
    14461 agtttgtagc ctttttgaaa gacttgagcg atggtatcta ctgggtgttc atcgtctgct
    14521 gggagagttt ggatggccat atggtagtta tggtcaaatt cgccatctgc tgcgatttct
    14581 tcaattcctt cttctttcaa agcgtgaatc aagctttctt gcaccatccc caagcccttc
    14641 ttcacatcat ctgtcaaacc ttcaactgca agtgcacgct caaggttgtc aagagatggt
    14701 aagattgctt ttgccaagtc ctggctacga taacgttgca agttttgacg ttcttcattg
    14761 gcacggcgtt ggatattttg catttctgca tgagcgcgaa gatatttgtt ttcgaactca
    14821 tctgcacgtt catttgccaa gtccaactca gacttttcag gagttgtttc ttcagctgtt
    14881 tccacaactt cctcttcttg aacttcttct acttcttcat tttttatatc ttgggccatg
    14941 ttcgcctcct ttaatgattt caatcttaat gtacttcgta atgattactg ctgaggtagc
    15001 ggtaaaaatc tgtcaacttc atggtcaaaa cacggttgac cacattgatt tgattgatta
    15061 gctgttggta atccagatta actggaccga taatggctag aattccaact ccccgataag
    15121 gaatgaggaa cttactacta atcaccgcta ggtcagctaa acaggactct tgaccgtctg
    15181 caatacgaac attttgcatc tgatcctcac gcaacccctc acgaatctcc aaggccacct
    15241 tttgcggttg gtcaaagaac tgataggctg ctagattggc aaaattcaag agattgacct
    15301 tgcccgccat cacaatgttt tcgttgaaca tttccttaaa gatgtgttca aagagatcga
    15361 tgacattatc cgttgttgta aagtaacgct ggataatctg cggaatctcc gtccgaatct
    15421 tgtagtgaat atctaaaacg gtgtgaccga ggaaacgttc ctgaatgatg ctcttcagtt
    15481 tcagcaaatc ctcctgcaag aagttccttg gaatcagaaa ctgactagta accgttcgcg
    15541 actcgtctag ggtaaatacc gccaaggctg tatgttgccc caaaacaacg atatcaaagg
    15601 ctgtcaaacg ttgcctgctc ggctcaacat ccagtgccac taccgtacag ccactcaggt
    15661 ctgttagcaa gttagcagcc tcttgcagaa tatcctccaa tttgaagaat tcctgatcaa
    15721 aggctttgac aatctcatat acctcatttt cagccagccg gtgaaaatcc agtgagtgtt
    15781 tcacatagta ctgaaaacca gcaacacttg gcatccgacc gcttgaagta tgagccttct
    15841 caagcaaccc ttgtttttct agttccgcca tgtcattacg aatggttgca ctgctagagt
    15901 taatagactc ttgcaaggct tttgatccga caggttcgtg cgttttggta aagatgtcaa
    15961 taatcagatt taaaatatcc tgctgacgct ctgtaaccat ctcatcactc ctctctgtct
    16021 gatcaattag cactcaatgc atccaagtgc taacttatga ttctattata cacccttaga
    16081 agagaatgtc aagacaaaaa ctcaaaaaat tagcactctt ttatcaagag tgctaaaaat
    16141 caatctgaag acctagaacc ttgctattca tctactcggt atttcctttt tagtctgaaa
    16201 taaccatgaa ttagataaga aatcagaaaa gcatataaaa caaaaataag aaagaaagac
    16261 atagaaagat cctctctaaa caaactcgta caaacaacaa gaccacctaa gaaagtagtt
    16321 gtacaggaac gaagtctaga tcgcataact tcccatttga gccccttact catatagact
    16381 tgatcctctg gaagtaaatc agaagacgat ttacgaagaa tcgaacaaga acctgctcct
    16441 atcaattccc aacctctatc tctaaaatct tgcagttcat gcttatattt tttaagaaat
    16501 ctagaatcat agatacggta gatgacatcg tctggttgac attggtcaaa atagaacaaa
    16561 ccaaaacgac tcgttctata cctccaacct ttcaaatgca tctcatgtaa atattcttct
    16621 tccttgtcca aatcaacaat agtgaaaatc cgaaattcta ctctgctatt cattgtctta
    16681 ccccaaaatt agaaaacatg cctggcgtta tttattagat aattctttcc gcttttgact
    16741 caatctccaa aaaatataag aaatctgaat cgcaaaaact atcaataaaa cccaatctat
    16801 tatgaaagtc aaaaacactt cccaactgaa agaactacct ccagtgacaa actttgagaa
    16861 aaacggtagt agagctaaaa agagaagcaa aataggaagc atccgcattg ttaaaatcct
    16921 tttggcataa aaaaatcttt atttaaacga aaatattatg gcaaaattta cgccagtttt
    16981 tgaacggctg atgtagatat tttatacttt caaaatgttt aaatgtgatt atttattttt
    17041 gaaaaatagc tcaccagccc gactgaaagt gcttataaat gataataagt cgcctgccga
    17101 aaacagcgaa aaatagcggt gttatgcgga gataatctga cgcgatgcga aagtatattg
    17161 catacttatt ttcaacaatt tagcagagta tttttataag tgtgatataa tagaagtata
    17221 atttgttctg atagtttatt ttatggagaa gtagattttt agaatgcgga gggttcaata
    17281 tggttgagtt tataaagtct aagaaagaaa tgagtgagga ggatattaaa gcaaatttca
    17341 tcactcctgc tattgtatcc aaaggatgga aaaatggtga gcatatcgct tacgaagaat
    17401 acttcactga tggtcgaatt gaggttagag gagataaggc tcgtcgtaaa gaaggaaaaa
    17461 aatcagacta ttcactgtat taccaatttg gaactcgaat tgcaattgtt gaggcaaagg
    17521 ataataaaca cagcgttcga gcaggattac aacaagctat tgaatatgga gagattttag
    17581 atgttccatt tgtttattct tcgaatggtg atggctttat tgaacacgac cgtatcacga
    17641 gagaagaacg tgagctggag ttagacgaat tccctactcg tgaagaatta ttttctcgta
    17701 tgacgaagga aaaaggattg acgtacgaaa ttacagaagc tatctcaact ccatactata
    17761 cagacgcctt ctcaatgaaa acgccacgct attatcagca aatagctatc aaccgtacta
    17821 ttgaaacagt tgccagagga caaaaacgag taatgtttgt gatggcaaca ggaacgggga
    17881 aaacgttcat ggcttttcaa attattcatc gccttcgaaa agctggtttg gctaaacgag
    17941 ttttattctt agcggataga aacatcttag tagaccaaac gatggctgaa gactttaggc
    18001 cattcgaaaa ggtaatgacg aaaattacac caaaactttt gactgctcct gaaaaattaa
    18061 attcttttga aatttatcta gggctttatc agcaactaac tggtgaagat ggaactgaaa
    18121 cacattatca aaaatttgac aaagacttct ttgatttaat cgtaattgat gaagcgcacc
    18181 gtggttcagc taaggaaaac agtaactggc gtaagataat tgattatttc agttctgcga
    18241 cacagattgg gatgaccgct actcctaaag aaaccaagaa tgcttccaat acggaatact
    18301 ttggtgagcc aatctatact tatagtttaa aacagggaat cgaggatggt tttttggctc
    18361 catatcgtgt tatgagggtt aatttagatg tggatgtgga tggttatcgt ccagaaactg
    18421 gaaaagttga tgctaacgga caattaatag aagataggta ctacggcagg aaagattttg
    18481 ataaaaccat tgtcattgat gatagaacgc aaagagttgc caagtttgtt tctgattata
    18541 tgaagcaaaa caatgcacga tttgataaaa caattgtttt ttgtgttgat attgaccatg
    18601 ccgagcgaat gcgtgctgca cttgtaaaag agaatctaga cttagtccaa gaagactatc
    18661 gttatgtcat gcaagtaact ggtgacaacg ctgaaggaaa agctcaactg gataacttta
    18721 tggatgtcaa ttctaatttt cccgctatgg taacaacgtc taaattatta acgacaggag
    18781 ttaatgctaa aacatgtcgt ttgattgttt tagactctaa tatccaatcc atgactgaat
    18841 ttaaacaaat tattggtcgt ggcacacgtc tttatcctca aaaggggaaa gaatttttta
    18901 cgattattga ttttcgaaat gttaccaatt tgtttgctga ccctgatttt gatggtgatc
    18961 ctgtgaaggt gctggaaaca ggtgcgaaaa cagtcagttg ttctacgccc ggtttcgtag
    19021 ataaggaagg tgacccagta gaaaaatata tcgttacaga caagcaggtt accattctta
    19081 attctactgt tcaagtattg gatgaaaacg ggaaactgat taccgaaagc ctgaccgact
    19141 acactcggaa gaatatctta ggtagctacg ccactttgaa cgattttatc acagtttggc
    19201 atacggcgga taaaaagaag cttatcttag acgaacttta taaaaaagga gtttatctag
    19261 atgctattcg agagtcggag ggaatatcag aacaagaaat cgatgatttt gatttactcc
    19321 taaaacttgc ctatggtcaa aaagaattaa ccaaaacgga acgtatcaat aaactcaaac
    19381 aaagcggata tttatataaa tatagtgagg aagcgcgtgc tgttttggaa attttactga
    19441 acaaatacat ggataaaggt attggagaac tcgaaagcat tgaaacatta aaacttccag
    19501 aatttcagat atatggtgga accttcaaaa tcatcaatac ttattttgga gataaaaaac
    19561 gatatttaca agcaattaaa gaattggagc aagagctatt tacagtagct taatgaaagg
    19621 aaagtatgtc aattacatca tttgtaaaaa gaattcaaga tatcactcga aacgatgctg
    19681 gtgttaatgg tgatgctcaa cgtattgagc aaatgtcttg gttattattc ttaaaaattt
    19741 atgatagccg tgaaatggtt tgggaattag aagaagacga gtatgagtca attatcccag
    19801 aggaattaaa atggcgaaat tgggctcatg ctcaaaatgg ggaacgggta ttgacaggcg
    19861 atgaattact tgattttgtc aataacaagt tattcaaaga gttgaaagag cttgaaataa
    19921 cttcaaatat gcctattcga aaaacgattg ttaaatcagc ttttgaagat gcgaacaact
    19981 atatgaaaaa tggcgtcttg ttacgccaag tcatcaatgt tattgatgaa gttgatttca
    20041 atagccctga agatcgtcat tcgtttaatg atatttacga aaaaattctt aaagatattc
    20101 aaaatgctgg gaactcagga gaattttata cgccacgtgc agcgactgat tttattgccg
    20161 aagttcttga cccaaaactt ggagaatcaa tggcagacct tgcttgcgga acaggaggct
    20221 tcttgacttc gactctgaac cgtttaagta gtcaacgtaa aactagtgaa gataccaaaa
    20281 aatataatac agctgttttt ggtattgaaa agaaagcatt tcctcatctt ttagcagtta
    20341 caaatctgtt tcttcacgaa attgatgacc ctaaaattgt tcatggaaat actttggaga
    20401 aaaatgttcg tgaatatacg aatgatgaaa aatttgacat tattatgatg aatccacctt
    20461 ttggagggtc agaattagaa acaataaaaa ataactttcc agcagaatta cggagttctg
    20521 aaacagctga tttatttatg gctgtcatta tgtatcgttt gaaagaaaat ggtcgtgttg
    20581 gagttatttt acctgatggt tttctatttg gtgaaggtgt aaaaactcgc ttgaaacaaa
    20641 aactggtaga tgagttcaac ttgcatacga ttattaggtt gcctcatagt gtctttgcac
    20701 cgtatacagg aatccatacg aacattcttt tctttgataa aacaaagaaa acagaagaaa
    20761 cttggtttta tcgtttagat atgccagatg gttataaaaa tttctcgaaa actaagccga
    20821 tgaagtcaga acacttcaat cctgttcgtg actggtggga aaatcgtgaa gagattctgg
    20881 aaggtaagtt ctacaaatct aaatcattta cacctagtga attggctgag ttgaattata
    20941 atttagacca gtgtggtttt ccaaaagagg aagaggaaat cttaaatccc tttgagttga
    21001 ttcagaatta tcaagcggaa agagcaactt taaatcataa gattgataat gtattagctg
    21061 atattttgca gttgttggag gacaaataat gacaccagaa caacttaaag caagtattct
    21121 ccaaagagcg atggaaggga aattagtgcc gcaaaatccc aatgacgaac ctgcaagtga
    21181 attattaaag agaattaaag ctgaaaaaga aaaacttatc agtgaaggaa aaatcaaacg
    21241 agataaaaag gaaactgaga tatttcgtgg tgatgatggg aaacattatg ggaagtttgc
    21301 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
    21361 gaggttttct acattggttg aaattgtcag aggtggctct ccacgaccaa tcaaagatta
    21421 tcttacttct gaagtagatg gaataaattg gataaaaata ggtgatactg aaaagggtga
    21481 aaagtatata aataatgtta aagaaaaaat caaaaaatca gggcttaaca aaactagatt
    21541 tgtaaaaaaa ggtacatttt tgttaactaa ttctatgagt tttggtagac cttatatttt
    21601 gaatgttgat ggtgcaatac acgatggatg gttggctatt tcgaactatg aaaactcatt
    21661 aaataaagat tatctattct atattctttc atcaaatgta gtttattctc aatttctatc
    21721 tctaattagt ggagctgttg tgaaaaactt gaatagtgat aaagttgctt ctattcttat
    21781 ccctctccct ccactatccg aacaacaacg aatagtagaa gcaatcgaat cagctttaga
    21841 aaaagtagat gaatatgctg aaagttataa tagactagaa cagctagata aagaatttcc
    21901 agataaacta aaaaaatcta ttcttcaata tgctatgcaa ggaaaattag ttgaacaaga
    21961 cccaaatgat gaatcagtcg aagttttact tgaaaaaata cgagcagaaa aacaaaaact
    22021 ctttgaagaa ggcaagatta aaaagaaaga tttggacatt tctattgttt cccaag
//
LOCUS       DAVIME010000031        21944 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVIME010000031 DAVIME010000000
VERSION     DAVIME010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21944
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.031"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VV588_001342"
     CDS             complement(381..1577)
                     /gene="tuf"
                     /locus_tag="VV588_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU7083680.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2499..3368)
                     /locus_tag="VV588_001343"
     CDS             complement(2499..3368)
                     /locus_tag="VV588_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU7083681.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3592..4212)
                     /locus_tag="VV588_001344"
     CDS             complement(3592..4212)
                     /locus_tag="VV588_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU7083682.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKAPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEPTPEPGTPKTETPVNLDPEV
                     PTYETGKREGLSNTGTEANATLASAGIMTLLASLVLGFFKKKEDEK"
     gene            complement(4170..5276)
                     /locus_tag="VV588_001345"
     CDS             complement(4170..5276)
                     /locus_tag="VV588_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU7083683.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSEGRTVTLVYRESEAPTTVTVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKENRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5387..5641)
                     /locus_tag="VV588_001346"
     CDS             complement(5387..5641)
                     /locus_tag="VV588_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083684.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5981..6427)
                     /locus_tag="VV588_001347"
     CDS             complement(5981..6427)
                     /locus_tag="VV588_001347"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU7083685.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERISIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLSLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6500..6825)
                     /locus_tag="VV588_001348"
                     /pseudo
     CDS             complement(6500..6825)
                     /locus_tag="VV588_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7059..8777
                     /locus_tag="VV588_001349"
     CDS             7059..8777
                     /locus_tag="VV588_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU7083686.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8888..9235
                     /locus_tag="VV588_001350"
     CDS             8888..9235
                     /locus_tag="VV588_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU7083687.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9514..10350)
                     /locus_tag="VV588_001351"
     CDS             complement(9514..10350)
                     /locus_tag="VV588_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7083688.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKLSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10363..10992)
                     /locus_tag="VV588_001352"
     CDS             complement(10363..10992)
                     /locus_tag="VV588_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU7083689.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASELLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11002..11643)
                     /locus_tag="VV588_001353"
     CDS             complement(11002..11643)
                     /locus_tag="VV588_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU7083690.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPREQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11789..13018)
                     /locus_tag="VV588_001354"
     CDS             complement(11789..13018)
                     /locus_tag="VV588_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU7083691.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13008..14174)
                     /locus_tag="VV588_001355"
     CDS             complement(13008..14174)
                     /locus_tag="VV588_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU7083692.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14318..15331
                     /locus_tag="VV588_001356"
     CDS             14318..15331
                     /locus_tag="VV588_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU7083693.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15376..15795)
                     /locus_tag="VV588_001357"
     CDS             complement(15376..15795)
                     /locus_tag="VV588_001357"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU7083694.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15806..17212)
                     /gene="atpD"
                     /locus_tag="VV588_001358"
     CDS             complement(15806..17212)
                     /gene="atpD"
                     /locus_tag="VV588_001358"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU7083695.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17298..18176)
                     /locus_tag="VV588_001359"
     CDS             complement(17298..18176)
                     /locus_tag="VV588_001359"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU7083696.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18192..19697)
                     /locus_tag="VV588_001360"
     CDS             complement(18192..19697)
                     /locus_tag="VV588_001360"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU7083697.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19712..20248)
                     /locus_tag="VV588_001361"
     CDS             complement(19712..20248)
                     /locus_tag="VV588_001361"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU7083698.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNLQANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20248..20742)
                     /gene="atpF"
                     /locus_tag="VV588_001362"
     CDS             complement(20248..20742)
                     /gene="atpF"
                     /locus_tag="VV588_001362"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU7083699.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20756..21472)
                     /gene="atpB"
                     /locus_tag="VV588_001363"
     CDS             complement(20756..21472)
                     /gene="atpB"
                     /locus_tag="VV588_001363"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU7083700.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21507..21707)
                     /locus_tag="VV588_001364"
     CDS             complement(21507..21707)
                     /locus_tag="VV588_001364"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU7083701.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21782..>21944)
                     /locus_tag="VV588_001365"
     CDS             complement(21782..>21944)
                     /locus_tag="VV588_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU7083702.1"
                     /translation="KKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKM
                     EIIFIKRFQ"
BASE COUNT         6546 a         4710 c         4002 g         6686 t
ORIGIN      
        1 actattgtat aatgcttttt gatttgagtc tagtattata ctcttcgaaa atctcttcaa
       61 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      121 ctaaaaacag tgttttgagc agtctgcagc taactttcta taacaaaatg aaataagaac
      181 aagacaaatc aatcaagaca atcaaatcga tttctaacaa tgttttagaa gtagatgtgt
      241 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      301 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      361 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
      421 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
      481 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
      541 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
      601 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
      661 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
      721 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
      781 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
      841 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
      901 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
      961 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1021 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1081 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1141 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgt
     1201 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1261 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1321 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1381 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     1441 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     1501 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     1561 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     1621 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     1681 tttacaacgt ttttgtgaat tattcttggt aaaaatttaa ctaattaata gaaagtacta
     1741 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     1801 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     1861 tcaaatcgat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1921 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     1981 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2041 aatgtaggtc gaagaatagc ccccctaatc gcttatttta tagcaaaatg aaatagaaac
     2101 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggggga
     2161 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2221 atattccgat aatatatagt agaatgaaaa ctgcacaatt tgattggaga attcaaacca
     2281 atttctaaca atgttttaga aacaagggtc tattatttca actgcaacct actatagccc
     2341 attgaagctg gaatagccca ctgagacttc taaaccactg ctggagagga gtttgtttag
     2401 agtttctttc atttccctaa aaaatcaaaa agagagaacc agtctgatcc tctcttactt
     2461 atagatggtg ctcactcaaa tgttaaagga gctatttctt agagataaag gaatttgaat
     2521 acagctactg ccgcaattgc tgctgcgata ggtgctacta ctggtaccca agaataccac
     2581 cattttgaat cgcctttatg ctcaccaaga actgattttg gaaggaaagc atgaaggaga
     2641 cgtggtccca agtcacgggc tgggttcaag gcaggtcctg taggtcctcc aagtgatgtt
     2701 accaaagcca taacgaggaa tccaagtgcc aagtgagcca cagaaagtcc tgaagcagtg
     2761 tgtggagcca cctgtgcttt aatagccaag tcagaaaaat caactgtttg tcctgcttct
     2821 attgcctttt gtttcatgaa ttgaagcact tcagcaccaa agaagttttt agtcaaacca
     2881 agagctgcaa agaacaaaac aaatgaacca acaaactcat taatcaaacc attgacagtt
     2941 gctgcatagc gactttcttt tgtaccatgg tcaatacttg aaatagttga gaaagttccc
     3001 aagatgttat ttgggttttc agttttcaag tagaatggac ggtatgttgc cacaactaag
     3061 gcttggccaa agatagcccc caagacttgc gcgataatgt aaggtaccac ttgtgcccaa
     3121 gggaaaagac cgctaactgc aagccctaga gtgaaagcag ggttgatgtg attcccagat
     3181 acgttaccaa acatcaaggc tgggatcata acccccatac cataaccaac agcgatgacg
     3241 atccagccac tttggtgacc tttcgtacct ttaagttcaa cgttggcaac tgcaccattc
     3301 ccaagaatga tcaaaatggc agttcccaaa aattcagtgg catacttcag tgcccatgtg
     3361 aaatccattt gctagattct ccttaaaatt ttttagatat tccttatttt atcaattttt
     3421 accctattta gcaactgatt tctggaaata tttttaaaaa aataggattc atagtttccc
     3481 agttcaacgg acttgtaagc gtttttattc ttcacgaaag acctcgttct caaaaccagg
     3541 aaaaaagccc acatctgtga gcttttcctg gttcctagat tctaaaatct attatttttc
     3601 atcttctttt ttcttgaaga atcctaatac tagactagct aacaaggtca tgataccagc
     3661 actagccaag gtagcattag cttctgtacc tgtgtttgac aatccctctc tcttacctgt
     3721 ctcataagtc ggaacttctg ggtctagatt cactggagtt tcagtttttg gagtacctgg
     3781 ttctggagtt ggctctggta ttggagtctc ttgatttggt agttctgggt ttggtgtcgg
     3841 aacacttgga tgctctggat ttggttgtgg gattggtttt tctggagttg gtttatctgg
     3901 tgttgataaa cggtcatacc ttaccgttat ttctttatca ctagagtctg acgtaacttc
     3961 ttgtgattca actgttggaa tatctggagc tttgtacttg tcaatcttac cagatacaac
     4021 ctcgtcccag tttcctgttg tccattcacc gtaggttaca actcccgtga ccttgttctc
     4081 agtttttgta cggcttaagg ttacaggttg aacaacatct tcttttacat tttggttcgt
     4141 aactttatca acgtaatgaa tgatacgcgt tatagtcttc gtctcagtag aggttgctgt
     4201 tttgggaacc actgtttcct caacattcta acggtagtaa tagtcaactg ttgcaccgtc
     4261 ttctggtacg catttgcagg agttgctacc aaggtgtatg ttgttttcct tgtgataact
     4321 cggttttctt tgtcctcagt tgttgttttc ccttcaatag tttttgattc tgtggtatac
     4381 tcagaaccta tcgctaaatc agcttttata acagactctg ccaacttctc ttggctacct
     4441 tctttatagt aattggctgt tactgtaaca gtggttggcg cttcgctttc tctataaact
     4501 aaggtcactg ttctaccttc gcttacaata ttcccagtta aacttgcaga atttgtatct
     4561 acttctttaa aagtataata ttttccgtca gtagtagtca tgctactgag ttttttatct
     4621 gtgacattgt agctggtacc aatcagttgt tttttattgg taatgtaggt tccgtcactt
     4681 tctttttctc caattccagt atcatttttc aatgatagca aacgcccttg ttcatcaaca
     4741 tagcgaactt tcacattttc tgagattagt tctgccaatt ctgaggtttt tttctttttc
     4801 ttgatttctt cggttatttt ccctttctct tcttcgggaa tatttagttt tggaatgatt
     4861 ttttcaacaa cggttcgtga tggttccaca gtatcttgga tgactgaaaa gtcagctaga
     4921 attgggagat tatactgaac acggtgactt tgagtgttta ctcctactct ttcattattc
     4981 tctgaaaata cttgtacggt ataagaaaca acatcttttc ctaatagaac atccccagta
     5041 gagaaatagc cgccttttcc tagtttgcta tctccagagc ccacttcttt cctaatctta
     5101 tcagatagtt ttttaccagt cagtacattc gttcgcacaa tccctttgtc tacccctaca
     5161 aagtgggaga actttttgaa ctcttcagaa ccagatctag cccaaccatt attaagggca
     5221 tttgcttttg tatttgtatt ctctctcaaa agtttggcga ttagaattat attcatcggc
     5281 acttagagtt gctgctatat ctgactcttg aataccaact tccttactac catttctagc
     5341 ggcagtatat gtgtatttat ctgtttctac ttctagctga ttatccttaa catgataggt
     5401 aattttctcc tggtataaga gtcttcagta gtttatatgc tctgtcatca tctttagctt
     5461 tagaagcagc tgagtttagc caagttgggg tattaggagt atctttatca gcctgtttca
     5521 agacattatt caagtcattt gctagcctat tggttgtcct cactgtgaaa gttttcttcc
     5581 agtctgaacc acttttatta gacttagata tgctcatgaa atcctggtca acattcaaca
     5641 caatatcgcc ttgtttttta gcatcttccg ttgcttctgc ttcaaattga tcatggagtt
     5701 tttgttgctc tggtgtatag tttttttatt tacacgattt aatgtactat tttttatttt
     5761 agtattaaga actccattaa tacgattttt aaactctgct tcaaaaaatc ccttaatttg
     5821 ttggtgcgca agttcaacat tcaaaccttt tttatacaag tcttcattct gaacgatttc
     5881 ggctacacgg tgaatggttt gattgtatac cgtcttctct taaccagcag tatccttagt
     5941 tttaatgact actcgatagg ttcctttaga accgttatag tcatctagtt ttaaaaaagc
     6001 attccaaaca ttcaaaaata gttggaactt cccttaataa atccgtcact ttctttttca
     6061 agatagccca agcttgctca ataggattca aatccggtga ataaggtggt agagataaga
     6121 aaaagtgttt atcttggatg cagagttcat ccaaaatgtt cttgggatga aaaccagcat
     6181 tgcccatgac aataacatga ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact
     6241 ccacaaagaa atcgcttgtc atgcttttct tgtaaatcat gggagctata aactctccgt
     6301 ctacttgtcc tgcaacaatt gaaattcgct caaaacgacg tccgctaatc ttttcataga
     6361 ctttctcccc tctaggagcc cctgcataag gacgatagag atagcggtcg attcctgttt
     6421 catcaatata aacaggtgct aggtgcttta aactattaaa attcttaaga aataaggcta
     6481 cttttctggg tcttgttcct taaagctcgt catctttttt taaagtgacc ttaatctgct
     6541 ttaaagctgc ccatactgaa ggaacagcac aatcaaaatg tgccgcaatt tcccgtaaaa
     6601 aagcatctgg atgagcctct acaaaggctt tcaattcctc taaaggaatc tttcggtttt
     6661 tgacgactcg ctttttcctc tctatgtgtt cttgttcacg tctttctttt cccacgtgaa
     6721 gagagttctg acgccaacac caaaaaactt ggctgcctcg acatggctgt gcccctcttt
     6781 gatgtaatct aatgctcgct gtttaaaatc agtactatat gccatagctt tattataata
     6841 tgcttgttta aaactaagta actatatcaa tgttttgtta tgagaagact tacttttttt
     6901 actgaaattg aatttttcct agcctaaaca tcatataacc ccaaaattca atctgacctg
     6961 gtttgaagag attttcgaag cagataaggt tttactaaaa ctaaaaaaaa tgatataatc
     7021 aaactgatta aatgttttaa aaataaagga gaatttgaat gtcttaccaa gaaaattacc
     7081 agaaatgggt tgattttgtg gagcttcctg actaccttcg tcaagatttg gaaaatatgg
     7141 acgaaaaaac taaggaagat gccttctata caaatcttga atttggtact gcaggtatgc
     7201 gtggcttggt tggtgctggt acaaaccgta tcaacatcta cgttgttcgc caagctactg
     7261 aaggattggc tcgtttgatt gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa
     7321 ttgcctacga tagccgtcac ttctcacctg agtttgcctt tgaatctgcg gcagttcttg
     7381 ctaaacacgg catcaaatct tacgtatttg aaagccttcg tccaactcca gaactatcat
     7441 ttgcagttcg tcatctcaac tgtttcgcag gtatcatggt cacagccagc cacaaccctg
     7501 ctccatttaa cggttacaag gtttacggtg aagacggtgg acaaatgcct ccacacgatg
     7561 cggacgcttt gactacttat atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg
     7621 atgtggaaac tgaaaaagct tctggcttga ttgaagttat cggcgaagct gttgacatag
     7681 aataccttaa agaggttaag gacataaaca tcaacccagc cttgattgaa gaatttggta
     7741 aagacatgaa gattgtctac acaccacttc atggtactgg tgaaatgttg gctcgtcgtg
     7801 ctcttgccca agcaggattt gactctgttc aagttgttga agcgcaagca actgctgacc
     7861 cagacttctc aactgtaaca tctccaaacc cagaaagcca agcagccttt gcccttgctg
     7921 aagaacttgg tcgtcaagtt ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc
     7981 gtgttggtgt tgaagttctt caaaaagatg gtagctacct caacctttca ggtaaccaaa
     8041 tcggtgctat catggctaaa tacatcttgg aagctcacaa aaacgctgga actcttcctg
     8101 aaaatgccgc tctctgcaaa tctatcgttt caactgactt ggtaacgaag attgctgaaa
     8161 gctacggcgc aactatgttc aacgtcttga caggtttcaa atttatcgct gaaaaaatcc
     8221 aagaattcga agaaaaacac aaccacactt acatgatggg atttgaagaa agcttcggtt
     8281 acttgattaa accatttgta cgtgataaag atgccatcca agccgttctt gtcgttgctg
     8341 aacttgctgc ctactaccgt tctcgtggtt tgacacttgc tgacggtatc gaagaaatct
     8401 ataaagaata tggctactac gcagaaaaaa caatctctgt tactctttca ggtgtcgatg
     8461 gtgctgaaca aatcaaagcg attatggcta aattccgcaa caatgctcca acagaatgga
     8521 acgcaacagc tatcactgtc gtagaagact tcaaggcaca aactgctact gttgctgacg
     8581 gtactgttac aaacttgaca actcctccaa gtgatgtgtt gaaatacaca cttgctgacg
     8641 gttcatggat tgccgttcgc ccttcaggta cagaaccaaa aatcaagttc tacattgcag
     8701 ttgtagggga aaccaacgaa gaatcacaag ctaagattgc taacatcgaa gcagaaatca
     8761 atgcatttgt aaaataaaga cctataaaag atgagaccaa ccaacctcat cttttttcgt
     8821 atcaaatcta agcaatttta gaaactttat ggcatactag acttatcaat gaaagcgagg
     8881 taatctcatg gaacaatttt tagataacat caaagacctt gaagtcacta cagttgtgcg
     8941 tgcgcaagaa gctcttgata aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg
     9001 cccttactgc cgtaaatttg caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca
     9061 catttacttc atcaatagtg aagaaccaag ccaactcaat gatttgcaag cattccgctc
     9121 acgttatgga atcccaactg taccaggttt tattcatatt acagatggac aaatcaacgt
     9181 ccgttgcgac tcttcaatgt cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat
     9241 cagctaacaa gtcttaaaat cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt
     9301 atgcgtttta ttgttcctaa aacagttaca tcagtatttc attacagaac attttaattt
     9361 tggaagtcaa atcaattttt aacaatgttt tagaaatcac agtgggctat tccatattca
     9421 attatccaga ttcaatcgct attatcgttt tcctagatta caaaaaaaac tacgttttgc
     9481 taatcaaaac gtagtctcag ccactatttt atcttactgt ccttctttta cttctttggt
     9541 tgctacatct tctccaaacc atttttggct gatttcttgg aacttgccgt ccttgtaaag
     9601 actagaaaaa gcttcattta tcttcttaac caaggttgta tcttccttac gggctccaac
     9661 cgcaaaagct tctgtttcta gtccaactgt aaagacatta taatcgttta aaacaccttc
     9721 tgcttctaaa taatagtttg cataaacacg gtcaatcaat agaccatcaa ttcgatcgtt
     9781 tttcaaatca atcaaggctt cattaaaggt ttggtattga ttcgcttcct tattagcgac
     9841 aatattcttc aaaagttctg gatttgcttc aaagtccgca taaccagatg aaccagcttg
     9901 agctcctaat gtctttccag tcatatcctt tgcagtcgtg ataccagata atttcttcgt
     9961 aaccaatacc tgctcattct tcatatatga gttactgaaa gccacctttt cacggcgttc
    10021 gtctgtagcg gaatagccat tccaaatcag atcaatcgtt ccttttgtca attcagcttc
    10081 tttcaaatcc caatcaatcg gttgccaatt taccgtgatt ccgtattttt caaaaacagc
    10141 tgtagctaaa tcaatatcaa atcctgcata agaaccatct ttctgagcaa atcccattgg
    10201 aacaaaagta ctatcaaatc caatagtaat agacttgtta gactggtact ttgaccaatt
    10261 atctccacta gtttcgctag aatttttccc acaagctact aagaacaaag cagtcatcag
    10321 actgactaat acaagcatcc attttttcat ccatttttcc tcctatttag gttctacttt
    10381 caataataca tctgcgatat tttcagcaaa ctgcaaatca tgggtaacca caatctgggt
    10441 catcccaagt tccctatttt gcaagattag cttctccact tccaaacgta attctggatc
    10501 cagggcagaa gttggttcat cgtagccaat gatttctggg tcaatcatca tagcacgcgc
    10561 caaagccact cgctgctttt gcccaccaga tagtgagaaa ggataggcct ctgcgtgtcc
    10621 tcctagtcct aactgttcca agagttcact cgccttcttc tcagcctctt cctgcttcat
    10681 tcccatggtc ttcacaggcg ataaagtcaa attttccaga actgatagat gaggaaatag
    10741 ttgaaaatct tggaagacaa atcccagtag gttgcgcttc tgcaattcat ccagctctaa
    10801 aggttgtcca ttataaaaga tttgccctga atcaatggtt tcaagacctg caagcatacg
    10861 taaaagagtt gtcttacctc caccagaagg tccaacgata gccaggattt gcttttcagg
    10921 aatacttaga ctgaaattag acaggatttg tttgtctcca aagactttat tgatatttcg
    10981 taattctaac atggcagcct cctatctata ataactatac ttcttctcaa cttttttgga
    11041 aataattgtc acaatcccaa tcaaaatcaa ataaatggct cctgccaaga acataggaac
    11101 cagactagca tcgcggttag cagctgttcg actagccaag ataaggtctg aaattccgag
    11161 agcatagacc aaagaagtat ccttgaccaa actcataact tcattaaaga cactaggaag
    11221 aacgatcttg gtcacttggg gcaagataat atagcgcact ctgtcaaaag ggctaaactt
    11281 caagaccttg gcagcctcat actgttctct tggaatagtg tcaattcccc cacggaaaat
    11341 ttctgcaaag taagccgcat aattcaaaac aaaggcaata atagctgcag gaaggcggtc
    11401 taaacgaatc ccaatacttg ggagcacata atagataaaa atcagttgca agagtaaggg
    11461 ggttcctcgc ataacccaga tgtaaatgtt aatcagataa tggaggggct tccaatggac
    11521 ttgcaaggca aaggcaatca aaacgcccaa gggaatcgaa aatagcaaga ccagtgcaaa
    11581 gacctgtaca gtcgtgctcg caccattcag taaactcggt aatatctcaa ataaataaga
    11641 catactgcac ctcctaaaag taattgttcc tattatagca tgaataaaca agattaccaa
    11701 gtatttttgt aaaaagattc taccatatac aaataaaaac cgtagctatc aaaagagata
    11761 aactacagtt ctatatgttt aaacattctt acaatctctc aaacagttct tgcatttgca
    11821 catcatctgg aaccagtttt aagtaagtgt gagcatggac ttttgcttct tcaaaatgtc
    11881 ccaattcacg caagagatag atatagtgtt ccagaaattc tggattgtcc ttcaaatctc
    11941 ctgtcaactc ttgataatgc tcataagcag tatccaaatc gtccatttct tgataagaac
    12001 gagcaatcat ccacttggtc aaaagatttt ctggctcctc actctgcaag tctagaatat
    12061 cctcataacg ctcctgctcc agataaatag tggctaaacg aagcaagatt tcttctgtat
    12121 cctcagcgtc ttcttttgca gtaaggagat aattttctgc accactagca tcatgcaatt
    12181 cataagaaaa ttgtgaagca gctagcaaga ggcgagtttc aaagggattt ttctctaatc
    12241 cttgcttagc gatacgcagg gcttcttgaa cttgatgttc cttatgtaaa gcctgactgt
    12301 acccatactc atagccttca aagtcaggag aaatggtatc aagctgctta aagtagaggg
    12361 tggctttttg atattcttct tgatcaaaat aaagactggc caactcaaaa gctgttaagt
    12421 catcgtattc taactccagg gctttttcta aaaactcagt agccgtttca aatttcccta
    12481 actgagcata ggcaaagcca attcgttgat aggtggaaat gcccgtttgc tcataaatcg
    12541 agcgattatc taactgggca taggcttgaa tagccgcttg gtaattttcc aactcactat
    12601 ccaactctgc caaacccaat atcaagagag aatcctctga gtaggtcaag gcctccaata
    12661 atttctcacg tgccacatct gtcaaacctt ccagctggta aaggtctgcc ttcagagcca
    12721 aagacgagac ataccagtca ctgtcagctt ggatttcctc aagataggta aaggcttctt
    12781 ctatttgacc atcctcgcta gcaattgcag ctagattaag atgaacctct ggaaaatcct
    12841 ctacaatttt caggtaaatt tccttggcct gaggatagaa accaatccct tcaagataag
    12901 ttgccaactc atacagaaga tcacttgaat cattttctaa agctttggcg aaataatgct
    12961 cagccttagt taaatcttgc tcctccaaag cctgtaacat ctgttgacta ttgttcactc
    13021 ttgacttcct caccctctaa ttcatataga ccactgacta ccttatacca ttcgaaaatg
    13081 gctgaaatga caaccttagc agaggcataa accggaatac caagtaaaac tccccagata
    13141 ccaaacatag atcctgaagt taacaaaaca aagagaacat taataggatg gatgtttaat
    13201 tgacttccca aaatcaatgg agagacaaaa cggccttcaa tagtttgttc tacaataaag
    13261 acaatcacta ctttcaaaag catgactgga ccagcaatca aacccaatac tagggcagga
    13321 agcatggcta gaaagctacc aagataaggg accagattta aaataccagc agtaaccccc
    13381 agcgtaaccg catagcgtag accaataatc ttgaagaaga tgataaacat tactgctaca
    13441 ataatagcca ctgtcacttg ccctcgaaca tagttggaca actgttgatt cacatctgat
    13501 agaacttgtc caacaggttc cttcaatttt cttggaatga attgggtcaa atagttacgc
    13561 aagcctttcc catcacgcaa gagataaaag agcatgaaag gaacgataat caaggcaaca
    13621 atcacttgag aagctccgct aataaaggca ctcacccagt tgactgcctg agatgaaacc
    13681 ttacttgcca aaactgtagc ctggctagaa aaattggtca aaacttgctc taattgaggt
    13741 ctgaaatcat ctggcaggtg ctgggctacc aatccattaa caatcctatc tatatcttct
    13801 aagtaaacag gaacgtttct tgcaaaggtc aaaacctgac gttgcagatt tggaatggcg
    13861 actgccaagc cccaaatgat aaagagagcg atgataacaa agacaatagt gatagctata
    13921 acacgattaa ccttatgctt ctccatccaa tcaacaatag gattcaacaa ataatataac
    13981 aaaccagaca aaatgactgg caacatcaca actgctataa agtctaaaac aggtgaaaat
    14041 agaaaactaa tcttacttaa aataaaaaga ttcaatccca ataataaggt tactaaaaat
    14101 accgtaattg ccttgttatc taaaaaccac ttgaaaaacc aagataggct aaaatgtttc
    14161 tctttttgct ccataaatac ttcctttcta ttgttctctc attataccat ttttgaaaca
    14221 aaataactct tttttaaagt gcttacatct aattgaatgt ctttaatttg cttgtttttg
    14281 tgatataata gtcttatctt tacacagagg tatagtaatg aaagaaactg tttattttgg
    14341 aacttataca cgtcgtactt ctcaagggat ttacaaggca gactttgata cagaaactgg
    14401 tcagctttca aatctagaac tttttgcagc tgagccaagt ccaacctacc ttgcctttga
    14461 ccagcaccaa catttataca ctgttggtag ccaagacgat aaggggggaa ttgcagccta
    14521 tcaaactgac gggactgtgt taaatcatgt tgttgaagaa ggagctcccc actgttatgt
    14581 tgctgtcgat gaaaagcgtg atttggttta cgcagccaac tatcacaagg gacaagtcct
    14641 tgtttataaa cgccaggaag atggtagtct tctacttagt gatatggatc aacacagtgg
    14701 ccaaggtcca catgaaaatc aagcttcccc ccatgttcac tatacagatt taacacctga
    14761 ccactatcta gtgacctgcg acttgggaac tgaccaagtc atcacctatg acctcgatca
    14821 agaaggaaaa ttatctaagc tctataccta tcacagcaag ccaggagcag gctcacgcca
    14881 tatcattttc cataaccact ataaaatcgc ttatctcatt tgtgaactca atagtactat
    14941 cgaagtttta atctacgatg gcgttggcga atttgaacgt atgcaggtta tttcaacttt
    15001 accagaagct tacgaaggct ttaatggaac cgctgctatt catctctcta aagacggtaa
    15061 atacctctac gcttctaacc gtggccatga ttctatcgca gtatatacca tccttgcgga
    15121 cggtagctta gagttattag aaatcgttcc aacgcatggt cagactccac gtgattttga
    15181 tttgacaccc gaccaaaaat ttctcattgt tgtccatcaa gactctgaca atgcaactgt
    15241 ctttaaacgt aattgtgaca atggtcgtct agcagaactc tccaacgact tccatgttcc
    15301 cgaagcagtc tgcatccgtt ttgctcctta aaacaccata aaaaatgaac ttggtatttt
    15361 caagttcatt ttttcttata gtctatttcc gacattaata cggttaatag cacgttgcaa
    15421 agcaatctta gcacgacgtt cttggtcaat caaatgtttg tcttgtgctt cttcaattgc
    15481 acgttctgca cgaagtttgg cacgttctgc acgactgata tcgatatcac gagcacgttc
    15541 tgcagagtca gcgacgattg tgatcatatc attggcaatt tcaataacgc caccgtttac
    15601 tgcaatccag ttcacgtgat ctttatcatc gatacgtttt acctttactt catcaactgc
    15661 taaaaccgca atcatatttt catgtcgtgg caagatcccc atctcaccat ccagagttcg
    15721 aaccgataca tagctggcat ggtgatcata gacgagacca tctggtgtca cgatctggac
    15781 agttaactga gccatagatc acctcttaaa atcccatttt ttcagctttt gcaatcacat
    15841 cttcgataga acctacacca cggaaggcat cttctggcaa gtggtcgtat ttaccatcaa
    15901 ggatttcctt aaagccacgt acagtttcag caactggaac ataagaacct ggctgaccag
    15961 taaattgttc cgcaacgttg aagttttgtg acaagaagaa ctggatacga cgggcgcgag
    16021 caaccaaggt cttttcttca tcagaaagct catccatacc aaggatagca atgatatctt
    16081 gcaattcatg gtaacgttga aggacacgtt ttacttcagc agcaactgca tagtgctctt
    16141 ctccaacgat ttcaggtgcc aaggcacgtg agcttgaagc aagtgggtca acggctgggt
    16201 agatacccaa ttgtaccaac ttacgttcca agtttgttgt tgaatccaag tgagcgaagg
    16261 ctgttgctgg cgctgggtca gtatagtcat ccgctggcac atagatagcc tggatagagg
    16321 ttacagaacc cttcttggtt gatgtgatac gttcttgcaa ttgacccatt tccgtagcaa
    16381 gtgttggttg gtaaccaacg gctgatggca tacgacccaa aagggcagat acttctgaac
    16441 cagcctgagt gaaacggaag atattatcga taaagagaag cacgtcttgg ccttccacat
    16501 cacggaagta ttcagcgatt gtcaaaccag taagggcaac acgcatacgt gctcctggtg
    16561 gctcattcat ctgaccaaag accatggctg ttttctcgat aacgcctgat tctttcattt
    16621 cccagtaaag gtcattcccc tcacgagtac gttccccaac accagtaaat actgaaatac
    16681 caccgtgctc ttgggcaatg ttgtgaatca attcttggat taagacggtt ttaccaactc
    16741 cggcaccacc gaaaagtcca actttaccac ctttaaggta aggggcaaga aggtcaataa
    16801 ccttgatccc tgtttcaagg atttcagaag aggtagacaa ctcatcaaaa gttggagctt
    16861 ttttatgaat tggctgacgc tctgcgtctt ctgtaaaagg agcttccaaa tcaatggtat
    16921 ctcccaaaac gttgaagaca cgtcccaaag tttctttacc tactggtaca gagattggac
    16981 gacctgtgtc caatacttcc attccacgag tcaacccatc tgttgattcc atggcgatag
    17041 tacgaaccat accatctcct aactccaagg ctacttcaag gacgattttt gtttttcttt
    17101 cgtcattttt gtagacgaca agtgcattgt taatctcagg aagtttttcc cctgctgcaa
    17161 acaaaacgtc tacaacggga ccgataacct gagcaatttt acctgaactc atctccttct
    17221 cctattctat ataagatact gtcggttcct agctcaacta ggtcctaagt tcattttcat
    17281 acgagctgga ctagagccta ttctaaggca ctagcacctg ctacgatttc tgtaatttct
    17341 tgtgtaatcg ccgcctgtct ggcacggtta tactgaattg tcaaatcatt gatgactttc
    17401 ttagcattat ctgtcgctgt ttgcatggct gtcatacccg cagcattctc agctgtcttg
    17461 gcatcgataa tggcaccgta aatcatactt tctgcaaact gaggcaacaa ctgctccaga
    17521 atttcttctc ggctggtttc caattcaaaa gtcaagctgt actcttcatc cgcttcattt
    17581 ggatccaagt caacaatcgg aagcatttgt tccacacgca tttgactggt tagcgtattg
    17641 acatggtggt tgtagcaaac ataaagctca tcaaagagtt cattttggta catttcaaca
    17701 gtttttgaaa taatcttacg aacttgatca aagctaggtt ggtctgccaa gccacgtaat
    17761 tcataaagtg gttgaatacc gcgagcctta aagaaatcag ctcccatccc accgatacag
    17821 atcatttcaa aacctttacc gtctgggtgg tattcttctt tcaactccat aacagctttc
    17881 aaaatagagg aattataacc tccaaccaaa ccgcggtctg aagtgataac gatatagcct
    17941 gtcttcttca cagaacggct aatcaacatc ggattagttg aagcaccagc tccattacca
    18001 tgaaggatat ctgtcaaaag tttacgcact ttctgagcgt aaacttggaa gttgcgagca
    18061 gcttcttcag agcgacctaa cttagcagcc gataccattt gcatggcatt agtgatttga
    18121 ctcgtatttt ttgttgaggc gatttttgtt ttaatatcat ttagagacac tgccatctga
    18181 cacctctatt cttattggaa gctagattga ttgagaaact ctgtaatcgc agcatccaag
    18241 actgcttctt ctggcaagtc ttttgtatca cgaatggttt ccaaaatctc tggatgttga
    18301 gcatcaaaga aggcatggaa ctcttcctcg aaacgaacaa tatcatctac tggaacagta
    18361 tccaagaaac catgtgtcaa agcataaaga atggttactt gtttctcaac aggtaatggt
    18421 ttgtgaacag gttgtttcaa gacctcaacg gtacgacgtc cacggttcaa cttagcctgt
    18481 gttgctgcgt ccaagtcaga accaaactta gtaaaggctt ccaactcacg gtatgaagca
    18541 aggtcgatac gaagtgtacc agcaaccttc ttcatggctt tgatttgtgc agaaccacct
    18601 acacgagata cagatgaacc cgcatcgatg gctggacgaa tacctgcatt gaagaggcca
    18661 tcgccaagga agatttgtcc atcagtgata gaaatcacgt tggttgcgat ataggctgag
    18721 atatctcctg cttgtgtctc gataaatggt agggctgtaa ttgatccacc accaagttca
    18781 tcagaaactt tagctgagcg ctcaagcaaa cggctgtgga gatagaaaac atcccctggg
    18841 aaggcttcac gacctggagg acgacgaagc aagagcgata gttcacgata agctaccgct
    18901 tgttttgata gatcatcgta tacaatcaaa acatgcttac cttgatacat aaattcttcc
    18961 gccatagcaa ccccagtata aggagctagg aagagcaatg gagatggttg tgaagcagag
    19021 gctgtcacaa cgattgtgta gtccaaggca ccgtactgac gaagtgtttc tacttgcgta
    19081 cgaactgttg attctttttg tccaatcgcg acgtagatac agatcatatc ttgatctttt
    19141 tggttcaaga ttgtatcaat cgcaatggtt gttttccctg tctgacggtc accgataatc
    19201 aactcacgtt gaccacgacc aatcggtaca agggcgtcaa tagctttcaa accagtttgc
    19261 aatggttctg aaacagactt acgttgcata acaccaggag ctggtgcttc tactggacga
    19321 gttttatcag tgtggatttc tccaagaccg tcaactggac gaccaagcgg atccacaaca
    19381 cgaccaatca gactttcacc tacagggact tccatgattt tccctgtacg gcggattgta
    19441 tcgccttcac ggatatctgt aaagtcacct aggatgataa taccaacgtc tgttgactcc
    19501 aagttttgag ccataccata agagccgttt tcaaaattca acaactctcc actcatgaca
    19561 ttttcaaggc catgagcacg cgcgataccg tccccgatat aggttacaac acctgtttca
    19621 gtcacatcaa aattgggttt gaaattttca atttgttgct taattaaagc gctgatttct
    19681 tgtgcgttaa ttgccaaaag aacaccactt tctatttcaa attttcttta acaactttaa
    19741 gttgttgttt aatactcaca tcaattgtct tgtgattggc aaaaatgaca aaaccaccaa
    19801 tgagactttc atcgatttgt tcttttacac tccttacttt cagagacatt tttttctcaa
    19861 tcaaagggag caaacgagtc ttctgttcat cagttagagg atgagcagac gtaatcgtca
    19921 cttcaaatcg atttgtttct ttttcaagtc ggttcaagca atctacaagc acatcataaa
    19981 aaagatttgc ttgtagattg taggccagaa cctggataaa gttttgtaat aaaggcgaca
    20041 cagaatcttg gaaaaaagca attgtttttt ccttatccga ctcgtctact gccacttgtt
    20101 ttaaaaaaga aggcagacct gttttttcaa caacttgctt gatttgagtc aagtctgaaa
    20161 agatacggtc ttcttctcct ttttcaagta ccaattggac aaaaggcatg ctgtattttt
    20221 caattacctt tactgttttc ttgtccatta agcttctcct agctgatcga tatactgatc
    20281 aatgagtgct ttatgggcat gactgtcaag gttttgtgag atgattttac cagctaagct
    20341 gatggtcaaa tctgcgacct cacccttaac actctgtaaa gcttctactt tattttgagc
    20401 aatttcttga ttggcttttt cttttaagtg tcctgcttct agtttagcat ctgctaagat
    20461 attagcctta ctttgctcag ctgtttcctt tgcattttca atgattgtct tagcttcttt
    20521 acggctacca gccaattcat cttcgcgttt ttgagccaat acttctgctt tttgacgggc
    20581 ttcttcagct ctgtcaatat ctgaagcaat tttttcagct ctttcttcga aaatgcctgt
    20641 aatattagac catgcaaatt ttttaatcaa gactagcaaa agaataaaag agccagtgat
    20701 taaaataaaa ttaccaatta attcacctac tgttacgtgc atcagttact cctttctatt
    20761 cctcttcaat attaatctta ttccctaaat acacagatgt caaaagagta aaaacataag
    20821 cttggatgca ggaaataaag acagaaaatg cagtccaagc caaattagct ccaaaggcta
    20881 ctggatacca ataaatagct tggtgggaaa gaagaagtaa caaactcgtc atgacctctc
    20941 ctgcaaagat attcccaaaa atccgcaaag ccaaagataa gaagtttgta aattcttcca
    21001 agatattcat cggtatgaca aaaacaggac tcataaaaga ttttatactt tttttaaatc
    21061 cacgacgacg aacgctttct atatgtgtca acaaaatgac aagaaaagat aaggttaagt
    21121 catactgtaa attagcggtt ggcgaactcc accagttagt cccatcgatc gtttgaagct
    21181 ttgtcattaa gccaaggtta ttggcaatca ccatgaaaag gaataaacaa aggaaaaaga
    21241 gtgagtaatc tttcatgtag cgcgaaccaa tgttaggttc tgtaaatcca ataacaaagt
    21301 catagacata ctcaagtaca ttttgctttc ctttgggttt caaggtcata ttgcggcttg
    21361 cccaataaat aaagacaaaa ataactccca caatcaacaa agtcatggct aacatagtca
    21421 gattgaagat aacaggacca atagagatga ttggattaat actttcttcc atctaaaatc
    21481 ctcccttttc ttctcgttcc atgtatttat ttgataataa atgagaagac aagagttaca
    21541 aagaaagttc cttcaataaa ggcaacacct aaaaacatca aactacgaaa ctcagaaagc
    21601 atatctggtt ggcgtgctac tgatttaaac agtccattca tcaataaacc ttcaccgaca
    21661 gatacgccca tacaggcaat acataagcct aaaaatgtta aattcataac aaattctcct
    21721 ttaaaataaa atttacttac ttagtgtagt cctaaaattt aaatttgtca acttttaacc
    21781 gctattggaa gcgtttaata aaaattattt ccattttgct aaatttcaag ttcaagttag
    21841 ccatccagaa gtcttctctg ggtgacttgt agtccaagca ttttttagga tagttgttaa
    21901 tccacttttc gatgaatgcg acttctttgg gagtcatttt cttg
//
LOCUS       DAVIME010000032        21776 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVIME010000032 DAVIME010000000
VERSION     DAVIME010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.032"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(279..1148)
                     /gene="rsmI"
                     /locus_tag="VV588_001366"
     CDS             complement(279..1148)
                     /gene="rsmI"
                     /locus_tag="VV588_001366"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU7083703.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(1151..1468)
                     /gene="yabA"
                     /locus_tag="VV588_001367"
     CDS             complement(1151..1468)
                     /gene="yabA"
                     /locus_tag="VV588_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU7083704.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1508..2398)
                     /locus_tag="VV588_001368"
     CDS             complement(1508..2398)
                     /locus_tag="VV588_001368"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU7083705.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2395..3033)
                     /locus_tag="VV588_001369"
     CDS             complement(2395..3033)
                     /locus_tag="VV588_001369"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU7083706.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(3253..4050)
                     /gene="proC"
                     /locus_tag="VV588_001370"
     CDS             complement(3253..4050)
                     /gene="proC"
                     /locus_tag="VV588_001370"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU7083707.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(4054..5316)
                     /locus_tag="VV588_001371"
     CDS             complement(4054..5316)
                     /locus_tag="VV588_001371"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU7083708.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(5326..6456)
                     /locus_tag="VV588_001372"
     CDS             complement(5326..6456)
                     /locus_tag="VV588_001372"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU7083709.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFEALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(6536..8419)
                     /gene="cbpE"
                     /locus_tag="VV588_001373"
                     /gene_synonym="pce"
     CDS             complement(6536..8419)
                     /gene="cbpE"
                     /locus_tag="VV588_001373"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU7083710.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(8422..9309)
                     /locus_tag="VV588_001374"
     CDS             complement(8422..9309)
                     /locus_tag="VV588_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU7083711.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9299..9760)
                     /locus_tag="VV588_001375"
     CDS             complement(9299..9760)
                     /locus_tag="VV588_001375"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU7083712.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(9757..10665)
                     /locus_tag="VV588_001376"
     CDS             complement(9757..10665)
                     /locus_tag="VV588_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU7083713.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            10658..10855
                     /locus_tag="VV588_001377"
                     /pseudo
     CDS             10658..10855
                     /locus_tag="VV588_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(10907..11578)
                     /locus_tag="VV588_001378"
     CDS             complement(10907..11578)
                     /locus_tag="VV588_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7083714.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(11632..11853)
                     /locus_tag="VV588_001379"
     CDS             complement(11632..11853)
                     /locus_tag="VV588_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU7083715.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            12125..12934
                     /locus_tag="VV588_001380"
     CDS             12125..12934
                     /locus_tag="VV588_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU7083716.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(13115..13990)
                     /gene="aguB"
                     /locus_tag="VV588_001381"
     CDS             complement(13115..13990)
                     /gene="aguB"
                     /locus_tag="VV588_001381"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU7083717.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(14000..15085)
                     /gene="aguA"
                     /locus_tag="VV588_001382"
     CDS             complement(14000..15085)
                     /gene="aguA"
                     /locus_tag="VV588_001382"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU7083718.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(15082..16209)
                     /gene="nspC"
                     /locus_tag="VV588_001383"
     CDS             complement(15082..16209)
                     /gene="nspC"
                     /locus_tag="VV588_001383"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU7083719.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(16209..17468)
                     /locus_tag="VV588_001384"
     CDS             complement(16209..17468)
                     /locus_tag="VV588_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU7083720.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(17465..18325)
                     /gene="speE"
                     /locus_tag="VV588_001385"
     CDS             complement(17465..18325)
                     /gene="speE"
                     /locus_tag="VV588_001385"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU7083721.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            complement(18356..18493)
                     /locus_tag="VV588_001386"
     CDS             complement(18356..18493)
                     /locus_tag="VV588_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083722.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            18580..19295
                     /locus_tag="VV588_001387"
                     /pseudo
     CDS             18580..19295
                     /locus_tag="VV588_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(19261..20736)
                     /locus_tag="VV588_001388"
     CDS             complement(19261..20736)
                     /locus_tag="VV588_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU7083723.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            21443..>21776
                     /locus_tag="VV588_001389"
     CDS             21443..>21776
                     /locus_tag="VV588_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU7083724.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVM"
BASE COUNT         6349 a         5039 c         3973 g         6415 t
ORIGIN      
        1 atgttttctc tatctcagct tttagttctt ctttattttc gtatgttcgc aaaaaatcac
       61 cttctttctg atttatcaat cctttgattt aaaatgacct tatttttcta tttatacctt
      121 ctaagaacgc tataactgct gctccaacca tcggtattcc gtatgggctt aataaaaaac
      181 ttaataccaa agcttctata ccaagtgata catctttata ttatcatcac taattaagtt
      241 aaacagaaac agacagaatt attacatcct gtctcccttt attgtttttc ttcccagtcg
      301 tggtaggcag cgtagagctg acttttattc cactggtaaa tcttagcgac ttccttgata
      361 gcttggtttt tcttcacacc ttgctggatg cgggtttgaa tttctacgaa caagtcttcc
      421 tcgtcctttt cctccacacc ctgactggca ccctcaacaa tgagaagaca ttcgcccttg
      481 agtggcgttt cagcaatgct ttctaataac tcagagatag tacctcgttg gtattcttca
      541 tagattttgg tcaattccct gaccaagaca acggagcggt caccgtagac ttctaacata
      601 ttttccaacg tgtctgctac acgatgaggt gattcataaa aaatctgtgt ttcaggataa
      661 tcttttttca agccaaaaaa ttgcttctgc tgacctgatt ttctcggtaa aaaaccgtaa
      721 aagatatgtg gctgtggcgc taaaccactg gcaatcaagg cagaaattcc tgcagaggca
      781 cctggaactg tcacaactgc aatttcttcc tcaatagctg ccttaactaa atcatgacca
      841 gggtctgaaa tgctaggcaa accggcatca gagacctgag caatactttg ccctgctttc
      901 aagaaaccaa tcaaatcagg aattttttcc ttggcattgt gctcatgaaa actgatctgc
      961 ttggtggaaa tgtcaaaatg cttgagcaaa agccctgtat tgcgcgtatc ctcagcagca
     1021 atccagtcca cttctttcaa ggtctggata gcacgaaaag tcatatcatc tagattgcca
     1081 atcggcgttg ccactagata cagcttgcca tagggagact gccccttaaa acttttttga
     1141 atttgcatgc ttactccctg tataacaact catcacagaa catacattct tcgtcctgct
     1201 ctcgacgttg tccataaaaa tcattacata cgtgaaatcc atcacggtaa atacgacgga
     1261 cactttcgcg aacatgcttg gccttgacgg gagcgtctgc ttccacctca cccaagcgtt
     1321 ctcgcaactt actattttcc aagcgaagag ctgtattttc ttctaccaag ctcttgagat
     1381 ttttcttgat ggcttccaca tcggctaagg ttaccaataa ttgttgggaa aaatcatcca
     1441 gcgcgtcaaa taattctttt ttgtccataa aacagccctt tcctttcttt atcattcatt
     1501 tttgagttta tatttctttc aagaccagat attccatggc attttgaaag ctgacattag
     1561 cttgccacat ttttctagct tctagtaaat cttgtagaat cactcttact cttacctgca
     1621 agaggtcctg cccacagaga acttcaagaa tccgtaaaac ctgatcctgt ttttccttat
     1681 catctgccaa gttggctaat ttggcaacct gtagataact ttcttttttc ttagctacta
     1741 accaagtcag caggcgttca ctttcatcga ccaaggtcca aaaacttgcc tgattagcca
     1801 acttttctgc ttcagctcgc gattgactaa acttagctaa aagagtcgct tttttcttaa
     1861 caagtcccat ttgttctaag agtaagataa gtttttcttc ttgcttttta aagtggaaga
     1921 tctgagtccg acttcggatt gtcggtaaca tcttttcctc atcgctagtc aagaagaaaa
     1981 tataaacttc actctggggt tcttcgatga ccttgagcag agaattggct gcgttgggat
     2041 gcattttatc cgcttgctcg ataataaaga cctgttgctg gctttcaatc cctgcttgag
     2101 aaaactgtcc caccaattcc cgaatgcgtt ctgtcttgat gacctgattg actggcttaa
     2161 tcaaggtgac atctggaaac tcttcctgtt caatcagctt gcaacttcgg catttctcac
     2221 atggtaagac gccaacttta tccgtacaaa agaggctctt agctaaaaat tgcgccattt
     2281 ccaagcttcc aaagaaacct gaaaagagat aggcgtgatt gagctggtct tgttctaaga
     2341 tacggacaaa acggtcaaac tgagctggtt gccaagcctt tagttgatct tgtttcattt
     2401 ggccaagtcc attccgtcaa acaagacagc cttggtagtt tccacaactt gctccaaagg
     2461 gagactagca tcaatcttga caatgcgatt tccttctttt tccaggagag aaaggtagcc
     2521 ttgacggact ttcttgtgca attccaaacc ttccaagtcc agacgattga cctcgcggtc
     2581 actattcgca gcaatgcgag ccagcccttc ttccacctcg atgtcaaaat agagtgtcaa
     2641 atcgggtttg aggccatctg tcgcaaactg attgagccag tcaatggctt caatatctaa
     2701 gccacgacca aatccctgat aggcaacaga actatcgata aaacgatcca tgatgaccaa
     2761 cttgccagct tcaagggctg gaagaacttt ttccaccaaa tgctgtctgc gactggcaat
     2821 atagagaagt agctctgttt tagcatccat ctgagtatga cttggatcca aaatcacttc
     2881 ccgaatcttc tccccaatca agactccgcc aggttcacgg gtcgtcagca cctttactcc
     2941 tttttcctct aaaattggta gcagagcctc taaaacactg gtcttgcctg ctccctctgg
     3001 tccctcaaga gagactaaaa atccttttga catgtctaac tcatttcttt tttactactt
     3061 ctattctatc aaaaaaatag gggtttgtga caatcttttt gtcttctcat ttcatactca
     3121 atgaaaatca aagagcaaac taggaagcta gccgcaggct gtacttgagt acggcaaggt
     3181 gaagctgacg cagtttgaat ttgattttcg aagagtatca accaccataa aagaggcaga
     3241 taaaactacc tcttatttac ctagttcttg tgttcgtttg taggcttgat gaactgcatc
     3301 catgactgtt cctcggaaag catgcgcttc taggcttgct acaccagcga tagtcgaacc
     3361 gcctgggcta cagacttggt ctttcaatac tccaggatgt tgctgacttt caaggaccaa
     3421 ttgcccagct cctaccacag tttgtgctgc cattttcaat gctatttctc gtggtaatcc
     3481 tgtctgaaca cctgcatctg ccaaggcctc gataaaaaga tagacaaagg ctggtccaca
     3541 acctgcaaga cctgtcgctg catcgattaa actttctcct agttcaacca agagaccagc
     3601 cttggctaaa agctgataaa agagctcact gtcctcagcc ctgcaattag gagacaaggc
     3661 ataactaatc actccttgcc cgatagaagc aggggtatta ggcatcatac gaataattcg
     3721 gtgttgactt gggataagac ttgctagttt ttctaaggtc aatccagctg ccatcgaaat
     3781 caaaagaaga ctttctcttt tttcaaggat ggtctggtat tgagaaagca gttcagaaaa
     3841 ctgagcaggc ttaactccta gaaaaatcac atctgcttct gcaaacattt cttcattgct
     3901 ggaagcctga ccaccaaagt ctgcaatgaa agcatctacc ttagcttgac tacgattggc
     3961 aaggagaatc tcatctgacg tcctagtctg caagacagat tttgccaagc tagcacccat
     4021 attccccaaa ccgataaatc caatcttcat ctcttactcc cttatctgcc catcaccggc
     4081 aaccacatac ttgtagctgg tcaactcttt caagcccatg ggaccacgcg cgtgcaattt
     4141 ctgagtagaa atccccattt cacaaccaag accaaattgt cctccatctg tgaaacgagt
     4201 tgaggcatta acatacaccg ctgcagagtc cacttgatct gtaaagtatg ctgcagcttc
     4261 agcattttcc gtcacaatag catccgaatg atgggtgctg tgggattcaa tgtgcgcaac
     4321 cgcttcttct aaactgctca caaccttaac agcaaggaca tagtctaaaa actcggtgtc
     4381 aaagtcttgg gtctcagctg cttgacctga aacaaactgg cttgctttgc tatccaagcg
     4441 gaattgaatt ggttccagtc cagcttcctt acgctctgca accagcattt gatccaagcg
     4501 aggaaggatg cttgctgcct tgttttcatg aaccagcaga acctccatgg cattacaaac
     4561 agaaggacga ctggttttag cattgttgat gatagacagc gccttgtctt cgtctgcatc
     4621 cttatccaca tagacatgga caatcccagt ccctgtctcg ataacaggta caatcgcatt
     4681 ctcaaccact gcattgatca agccagctcc tccacgagga atgagaaggt ctagatagcc
     4741 cttggccttc atcatagcat aactactttc acggctagta tcctccacca gttgaatcac
     4801 atttggatga atagtagtcg tctccaagcc cttcttcaag gctgtgacaa tggcatgggt
     4861 tgtttgatag gcatccttac cactacgaag aacaaccgca tttccactct taagagtcaa
     4921 agcagccgca tcagacgtca catttggacg gctttcatag ataataccga tgacacctat
     4981 agctacacgt ttttttgtga taaccaaacc attttcaagc tgacttgttt ctaaaacttc
     5041 accgattgga tctggtaagg caaccacttc acgaattcct cttgccatcg cttctatacg
     5101 atctgcatcc aaataaagac gatccaacat cacatctgag attttcccct tagccgctgc
     5161 catatcgagg gcattagccg ctaaaatttc ctcagtagca gccactaagt gatcagccat
     5221 ggctagcaag gcttggtttt tcacttcttc actagctgtg ttaatcgatt ttttaacagc
     5281 ctgtacctgt tcaaattgtt cttgtctact caccatagtt tacctctaaa attctgtaaa
     5341 aagtagttgg atttcaggag taatggaaat ccagtcgtca cggtaaatca agacaccctt
     5401 ggctttttga gaacgcaaca tatcctccaa agcagatgct ccaaattgca cgcgtccttt
     5461 tccaagtgat tttccacttt ccttgtcaaa tactgtcacg atatcaccgt aagaaaaggc
     5521 tccttctgct tcaacgatac cagataagag aagactcttt ccatgttgag agagagcttc
     5581 cgcagcccct ttatcaaccc aaatagaacc ttgactctga gcatagaagg caagccattg
     5641 tttctgggta cgaagcccct tctcttgagc aacaaagtaa gaaccatcct cggtctcctc
     5701 tgccgcctca atcatggaat ctgatttcaa ggatgagcag atataaacag gaactcctga
     5761 ttccgtcgcg atagttgcag ccttgatttt ggttaacata cccccagttc cgtttgacga
     5821 accagctcca ccagccatat caataatctc acgattgatg gtctcgattc tctccaagcg
     5881 tttggctctt ggatctgaat taggatttcc agtatagaga ccgtccacat ctgtcaagaa
     5941 aactaaaagg tctgcttgga ccatcgccgc tacttgagca cttagagtgt cattgtcccc
     6001 aaccttgagc tcatcaataa cgacactatc attctcattg atgataggaa ttgccccacg
     6061 gttgagcaaa accgacaaag cctgatgggc atttttataa cgacgcttat ccacaaagtc
     6121 atcttgggtc agcaagattt gtgcagaaac gatttgacgc aagagaagat tggtcgtata
     6181 ttcttccaac aaaagtccct gccctaccgc tgctgaagcc tgtttatcag caattttagt
     6241 cggacgcttt ttaaatccta aggcttcaaa accagccgca atggcacctg aagacaccaa
     6301 aatcaactca tgaccagcct cgtgcagcat agccaactgc tgggtaatat cctttacctt
     6361 actacgtgat aaacttccat cctcatttgt cagagaagaa gtacccacct taaagacaat
     6421 ccgtttgtat ttcatagtct cactccgatt attcatattt atccattata acatgaataa
     6481 caggaaatag aaaagagttg ataggaaaaa gaaggcccta aaaccttctt ttctactact
     6541 gttctgattc cgatttgttt acactcgttt cagagctttg tgaagttgag gatgtcaaat
     6601 cttgactagt tgaaaaattt gtaacacttt catgttgact cgtttcttta ttttcaagat
     6661 cctttttcac tacttctttg gattctttta tttctgaatg acttgtagtt ttaattgtag
     6721 cagatttctc gatcgaaaca tccactaacc aggcaccact tgaatccaca gtataacctt
     6781 ctggtgtctt accgttcaca agtaattgac cattttcttt caagaagtac catttatcct
     6841 tgtccttgat ccaacccaca gctcgtgaac cgtctgtctt gtagaaatac caatcatttg
     6901 cctttttatg ccagccttgc ttcatagctc ctgaatcttc cagataataa tgttgaccag
     6961 caacttctat ctcacctgtc ttcatgacac cagtagaatc catatagtac caggtttctt
     7021 tatcttttac ccagcccatt ttcatttccc ctgatggagc aaagtaatac cattgcccca
     7081 tatattgaag ccatcctgtc ttcatagaac catcaacatc caaataatac cactgctctt
     7141 tatcttgaat ccaaccaatt tccatctggt tttctttgtt aaaataatac cagattccag
     7201 cgattttctt ccaattttta gcagaagcac cagagtctgt caaatagaac caatgattgt
     7261 tccatttttt ccattgattc tgtaacaaga tacccgtttg gttaaagtaa taccattcac
     7321 cttcgatttc attccaaccg acagcatact ctcctgtaga atcaggcgct tgataccacc
     7381 agttcccata tgcactctta tgccaaccag cttgaaaact tggaatcggc ttgtaggatg
     7441 ttgaaatatt gacaaaaccg tcttttcgaa tatcaaaaac tgttgcatca tagtctttgc
     7501 tggctgcgtt gattctctca attcctcgtt ctttgagcca attaacatac tcactatcaa
     7561 caccattttt ccaaggtaga ctatccgaag tttgaacaat caaactcgga ctcaaatttt
     7621 taatgaaatc cttggtattt gatttgttgg tatcatggtg atgattaaac ttcatcaaat
     7681 caacttttcc aatgagagga ccatacttgt cttctgctcc atgaacatta tctaaatcgc
     7741 ccccaaggta aattttcttg ccattgactt tcaccacgct aatcaaggaa ttggaattgt
     7801 catcccaaat tttctttaat tcacccgatg aatcagtttc attttcataa ttatagagct
     7861 gaatatccat gtccccaaac tgaaaatgag catccccttg tgtgatattt tgaataactg
     7921 aaacaccttt ttctgcagca gtctgtaaaa ccttatcata gccatacaga ttatcccata
     7981 gacgttcaga attagtaata cgactatcac tatatttctt aagatagact cggtcaactg
     8041 gataggtaga cagtaattca tcaacatttc caatatgatc actgtgggta tgggtcacca
     8101 aaataaaatc aagtttttgg acacccaatt ccttcaaacg acgaaagaca cggtctgtta
     8161 gaacatgctt ataagacgtt tcaattcctt ctctccatgg atagcgagaa tcacttccat
     8221 ctgggaaatc ataatcttct cctgtatcca ccatggcaaa atgtccattg ctttcaagaa
     8281 taatcgcatc actgccacct tcttgaacat tgataaagtg gattttattt cctgaacttt
     8341 cttgagcctg aacattccca taccatgaca aacctaaaaa agcgcctaca agtgctaaac
     8401 tagttaattt ctttttcatt cttactttct caatctctcc aaggtttcct taaaaatctc
     8461 tgggatatct gctttaaatt ccaaggtctt acctgttctc ggatgagtaa aacctaaagt
     8521 cttggcatga agaaattgtc catgtccttt caaagtcttg cgaggaccat agacctcatc
     8581 accagcgact ggatggccga tataagccat gtggacacgg atttgatgag tgcgccctgt
     8641 ctccagttgc aactctacta agctataatc gccaaagcgt tccaagacgt gaaaacgcgt
     8701 cactgcaggc ttccctttag cagttacagc ctgtttctta cggtcttttt cactccggcc
     8761 aatcggcgct tcaattacac cacgatcatt aggtagattt ccatgaacaa tcgcccaata
     8821 tttgcggaga gactttttat ccttgagttc ttgggcaagt gctagatgcg catcatcgtt
     8881 tttagcaatc atgagaagac ctgacgtatc cttatcaata cggtgaacaa tccctggacg
     8941 cagaacccca ttgatacccg acaagtcctt aatatgatac atgagggcat ttactagggt
     9001 tccactggta tgaccagcac tcgggtgcac aaccattccc tgaggtttgt taacgacagc
     9061 cacatcctca tcttggtaga ctatttctag cggaagatcc tcagccacat actctaatac
     9121 ctctggttct ggcacatggt aagtgacgac atcaccctct tggactgtgt atttagcttt
     9181 cttgacttga ccattgacca agacctggcc tgatttaatt tgttcattcg cgagactacg
     9241 tgataattct gacaaatctg acaaagcctt atccaaacgc agaccaccag tttcaatttt
     9301 aatttccatt tatttcctct tttagcattg caatcaataa aataatcact ccaaccgtca
     9361 gatagctatc tgccacattg aaaattgcaa agttgataaa gtcaaggtgg aacatatcca
     9421 caacaaagcc ctgactgacc ctgtcaataa agtttccaag accacccgcg attattagag
     9481 tcaaacccaa gaccatccag aatgagtcct ccatgtgttt atgtaaatac caaatggcac
     9541 ctatcacgac aaccagagta atgacagcga ataacaactg ctgatcttgt aagatagaaa
     9601 aggctgcacc tcgattttgc aggtaggtca agctaacgaa attggggatc caggagcgca
     9661 cttcacccag tggaatctgc tggacgatat aggatttgac caactgatcc agcccaatca
     9721 aaagcagtac aatgactgcc actattgctc tttttttcat gatttcctct tttgatcaaa
     9781 atattcttgc atgacttcta cgaagagagt cccagcttga ctaagctcca cttcttcacg
     9841 tttaacatag accatgcggt tatctaggtt atccttgaga cgaataactg taatgccatt
     9901 aacactgtca ctatctaaaa atccagaacc tgtcgcatag gcgtccgtcc gctccaaaat
     9961 accattcaag gtggcacggt ctgtcacatt aaacatctgt gagctagcgc tggtatcaac
    10021 aaagttctct gaataataaa ggtactcgtc tttctcttga gtgaaacgaa ccgttggtaa
    10081 atccgctaaa tcctccatga ctaattcctc tttctgggct aaaggatgac cctcacagag
    10141 ataaatatgg gtatggaaag gaatcaattc gatgacctcc agacctaact tttcaacccg
    10201 ttgcataatc ccctttttat tttgattgtt gaggtagata atcccaatct cactatgccc
    10261 ttgcgccact tcatctaata tttgaacagt agttgattca aaaatacgga agttcttata
    10321 gtcaggatag cgctctgaaa aggccgtaat agttggtggt aagaagtcat agtgctggct
    10381 agcaacggaa aattcatctt tttcttcttc aggattggca tactgatttt gaaaaatatc
    10441 aaatccttta accaattctt gcgctttttc ataaaattcc atcccacgac gggtcaagaa
    10501 agtccctgag ctggtccgac ggaaaatctt aaaacccaac tctttttcca aatcccgaac
    10561 agaaatagac agactcggct gactaacata catcttttca gcagcttcac gaaaagtacc
    10621 actattggca atagccacaa catagcgtaa ttgttgaatg ttcatcttct acccctaact
    10681 tctttatctt ttcattatac catattttag aagttttcca aaaaggaaaa aagaacatcc
    10741 tattcttctt aactatcttc actatctgcc tttctcaagc caaccttatt ttcaaaatca
    10801 attcaaaaaa ataactggct acacaccact acaatatcga aaagaaaaac gttgactatt
    10861 tgtgaaaaaa gaaaatgccg gaaagttccg acattatttt agtaagctaa cttcctgaaa
    10921 ataggagcaa ccacacatcc cagaaggcag tgatattaat gagaatatga actagtattg
    10981 gatagtagag atttttagtc atgcgataca atagagctaa aataagacct ccactagcat
    11041 aaatgaaaaa agcaagagga gttaaagcaa aattgatatg aatataaccg aaaataatag
    11101 cagaaagcaa aacatctccg taccaaggcg agtttttgaa aaaggttgtc ataatcacac
    11161 cgcgataaat caattcctca gcaatagggg cgatgaagca aacgatgagc aagaaataag
    11221 ggaactcctg tctccccatc atttctaccg tttcattcaa agaaatctga tttgaagaca
    11281 gggatatgaa atacgaaaag aggaagtcag acatatatga aatgatgtag cccagtaaaa
    11341 ggtagatgaa gtacctcagc tgccacttga aatgaaaaat tttctttcct gcaaaaacca
    11401 gtagatagat gaccgctaag aaaagaactc cgctctccat caaaagcaga atctgaaaaa
    11461 attcacgact tgctggtaga tagggctttg cgaggtgatt gaaaactctc caaaaccaag
    11521 ttgatttgta aaaaattaag gacaatgcta gtaaaatttg aatagcccgt tttttcatat
    11581 taaattctct gctttctcca cttgtttctt catattacta ataaatttta cttaaaatct
    11641 cgcagcactt cctttgcaaa gatgattgcc tcctccaata tatcctaaat cataggtgcc
    11701 tctgggacaa aatccatgaa ccggcagagt taatactggt tctatttccc aatcgtacct
    11761 accattagga tttttaccat atgaatctgc tccaccttgt atcagctcta attcttcatt
    11821 tgttagattt atattttttg tcattaaaat catgatatat ttcctccatt attcttcaga
    11881 ttagttgagt aatctgatac tcatacctac ttacaaaaaa actattatat taagttggtt
    11941 ttttaatttg tctagttgca acattgacaa acatagtata gcatatcttt gcgaaatatc
    12001 ctcttcaaat catgaattgt catcaaaaca tcttaaacta taaaatcaat tagtctcaag
    12061 ctttctatca atttcttctc caaaatatgc tataataata gcaaaagata aagaaggaag
    12121 acctatgatt aaactactag ccttggatat ggatggaacc ctcctcaatg aagccaagga
    12181 aatcccacag gctcacatcg ctgctattca ccaagccatt gaaaaaggtg tcaaactggt
    12241 cctctgtacg ggtcgccccc ttttcggtgt cctcccctac tacaaaaaac tgggactcga
    12301 cctccagaac gaatatgtga ttgttaacaa cggttgttca actcaccaga ctagcgactg
    12361 gggcttggtt gactggcaag aactgagtcc agctgacatc gaatacctct atgaccttgc
    12421 tgaaaagagt gatgttcagt tgacactttt tgacgagtca cattattttg ttctcggtgg
    12481 caagcccaat caagttattg aaaatgatgc taaactagta ttttcagacc tgactgaaat
    12541 ttctcttgag gaagcgacta gtggaaagtt ccggatgttc caaggtatgt ttttaggaac
    12601 aaaagaacaa acagacgatt ttgagcagcg ttttgctgaa gagctttgcc aacgattcag
    12661 tggagttcgt tcgcagcctg tcatttatga agcaatgcca cttggaacga caaaggctac
    12721 tgctctttca cgactagctg agattttgaa gattgattcc tcagagatta tggccatggg
    12781 cgatgctaat aacgatatcg aaatgctcca gtttgcaggg cttgggattg caatgggaaa
    12841 tgccagcgat tatgtcaaat ctcttgcgga tgccgttacc tcaagcaacg aagaagacgg
    12901 cgttgcgcgt gctattgaga aatatattct ataaaaaaga aaagcaaata gacagaagtt
    12961 actgctattt gcttttttgc taatatttta aaatacggac taatcaatag acaagaatag
    13021 cgaatcataa aaatcgattt actagatgcc atagtatctt atagttgcta ataagaagtt
    13081 agtctagcag aatgaatctc tcatttctcc cacactaatc tgtaatttgt ctatacattt
    13141 ctggtcttct atctcgaaac aagccccagt ttaggcgttc actcgctccc ttgtctaggt
    13201 cataagtagc taacagaaca gcttcttctt gtctttcagc tcgttctaga atagctcctg
    13261 tttcatccgt cataaaggag gaaccgtaga agtcaagact ggaactctgt ccgccatttt
    13321 cctcactagg agtaacctcc tctaaaccat aacgattggc tgcgatgact ggaacaatat
    13381 tcgctgctgc gtgcccttgc atagtacgtt gccagtgacc acaactatct gtatccaaaa
    13441 tcggctctga accgatggct gttggataaa agagcaattc agcaccattc aatgcaagac
    13501 agcgcgctgt ttcagggaac cattgatccc aacagatacc gataccaatc ttagcatagc
    13561 gagtattcca gaccttgaaa ccagtgttac caggcgtgaa atagaatttt tcttgataat
    13621 aatggtcatc tggtatgtgg gtctttcgat aaacgcccag cacttcccca tctgcatcaa
    13681 tgacggcaat agagttatac aagacattac catctttttc atagaaactg attggtaaaa
    13741 caacttgtag ttccttagca agcaccttaa aatgctgaat ggcagtattt tccgctacag
    13801 attgggcata ctggtagtag tcatactgac gttcctgaca gaaataggga tgttcaaaca
    13861 actcgggcaa gagaataatt tgggctcctt gctcagcagc ctgacgtact aaacgctctg
    13921 cggtttggat atttgttgcc acatccttag cgcattgcat ctgaatggtt gcaactctta
    13981 catttctcat ctttttctcc tattctggaa tttgttgggt gatacagtgg atattgccac
    14041 cacctaagag aatatctctg gctggtattc cgacaacttt acggtctggg aaacacttgc
    14101 tgaggatatc taaggccact tggtcgttta catcctcaaa ctgtggaacc aagacagcct
    14161 tgttggcgat ataaaagttt acgtaggaag ctgctagtcg ttcacctgcg tatcgctttt
    14221 cttctccttc ttcatagatg tagcctggca aatcttcttc tgtcacaact tgtcgaactg
    14281 cagggatagg caatttatga atggtgaagt gacaaccttt tgcatctgtt tcctgttcta
    14341 agagttcgag atctgctttt gacatggcat actggggatc attttcgtca tctgtccaag
    14401 ccaaaacaag ctcagcagga ccaacaaagg cagcaacatt atcgacgtgt tcattggttt
    14461 catcctgata aataccataa ggaagccaaa taactttttc agcaccaaga ctttctaata
    14521 atgtgttttc aatctcctct ttagtcaggt taggattgcg accaggacta agcaagcaac
    14581 tttcagttac gagaatagtt ccttgaccat cgctatggat tgcgcctcct tccagtacaa
    14641 aaggtttagc atcatagaca ggcctttcca aggcctcagc aaaacgactg gctacttggt
    14701 catcctcttc ataatcttga taaagaccat cataggtgcc tccccaagca ttaaaggccc
    14761 aatccacggc taatttctta cctttatcat tgacgagaat ggttgggcca gtatcacgcg
    14821 cccaggcatc attggtggga atgtctaaat aaacaacctt gtctccaaga taggattggg
    14881 cttcagatag ataggcctgc tccaccaaaa gatagactct ttccccttct gctatggtct
    14941 cgatgatctg agtaaatgct cttttagcag cctttccttg aaaaggccat gatcctggtc
    15001 gagtcggcca tatcatgagg gtaccatgat ggggttcgta ctctgctggc atgtgatagc
    15061 ctaatttttt tggactgtcc atcatgataa tctcccttta aagtcttgat agccaaaagc
    15121 tttgagtaag ctacagtctc cctgttcgtc catgagatag agacttggca atccaatacc
    15181 attaaaggta ttatttttga caaaagaata aatggccatg tcttgaaaat aaagtctgtc
    15241 tccgatttgg actggatttt caaaactata atcaccaatc acatcgcccg tcagacaggt
    15301 attagaagaa agtctgtagg tatgggcttt ttcctgtgac tcaaagccat ttctcaaagg
    15361 tggacgatag ggcatctcaa gtacatcagg catatggcag gtcgcagagg cgtctaaaac
    15421 caagatttcc ataccgtttt ctacaatatc taatacctca gttgctaaat aacccgcatt
    15481 aagcgcaatg gcttcaccag gctcgatata gatttcaaga ttgtaagttt ttcggatacg
    15541 cttgatttct gaaatcagca aatccacatc gtaaccttct cttgtaatat gatgaccacc
    15601 acccatattg agccatttta cctcatgtaa gtagggacca aactgttctt ctactgcttt
    15661 caaagttgtt tgtaaatcat ctgctccctg ctcgcaaagg gtatgaaaat gaagtccgtc
    15721 aaccaaatct agcaaatcac tcggaatctt gtctatagta actccaaagc gagaacctgg
    15781 tgcacaaggg tcatagagcg cgtgatctcc ttgagttgaa cactgagggt tgaggcgcaa
    15841 accaacactg acaccagcct ctcgacaacg cggaccgtgt ttacgcaact gtctctctga
    15901 gttaaagacg atatggtcca ttatctctag caattcctcc aagtctgcat ccttgaaagc
    15961 aggcgcaaat acatggactt caccaggaaa ttcttccctt gccaatttgg cctcatagag
    16021 tccactagct gtcgtacctg atagatactg gctaatcaag ggataagttt tgtagaggga
    16081 atatgccttc tgggcaagca agaccttgca accggcctct tcttgtacat attgtagaat
    16141 gcggcaatta gcttctaact tggccaagtc aataacatag gctggtgttg gtacttgttc
    16201 taacttcatt agtccaccat ttgtggattt tcaaccacaa cccatggcaa accatactca
    16261 ttcaaagctt ccatgaatgg atctggatct aactcctcaa ggttatacac tccagcttgt
    16321 ttccaagttc cgttcatgac taattttgtc ccaatcatgg ctggaactcc tgtcgtataa
    16381 gaaatagctt gcgaaccaac ctctgcgtaa cattcctgat ggtcgcagac attgtagata
    16441 tagatagtct ttttgacacc gtctttgaca cctgtaaaga tacatccaat attggttttt
    16501 ccgactgtac gtggcccaag actggcagga tctggaagca aggctttcaa aaattgaatt
    16561 ggaacaattt cttggccgtt aaagttaatg gtatccgtac gaaggagtcc aacattttca
    16621 agacatttca tgtgcgtcaa gtaagattga ccaaaagtca taaagaaacg aatgcgtttg
    16681 acacctggaa tgttcttggc caatgattcg atttcttcat ggtgaaggag atacatatct
    16741 ttttgtccaa cttgagggaa atcatactca cgcttgatag acatagcttc gacttcgacc
    16801 catttcccat cttcccagta agaacctggc gcagaaacct cacggagatt aatttctgga
    16861 ttaaagttgg ttgcaaatgg ataaccgtgg tcaccgccat tacagtctaa aatgtcgata
    16921 taatggattt catcaaaata gtgtttgagg gcataagctg aaaagacact agttacacct
    16981 gggtcaaaac cagaaccaag aagagcagtc aagcctgctt ctttgaattt ctcttgataa
    17041 gcccactgcc atgagtagtc aaagtaggct gtaaaaccaa gttccttaca acgtttttcg
    17101 tagatagcac gccactcagg gtcttctgtg tcttctgctt cgtagttggc tgtatcgata
    17161 tagtgaacac ctgttgccaa acaagcatcc ataatggtta aatcttgata aggcagagct
    17221 acattcaaaa cagcttctgg tttgtagctt tcaatcaggg caatcacttc ttcaaccttg
    17281 tcagcatcaa gtgctgcagt ttcaatttta gtacttgttt tgccttctag cttcgctttc
    17341 aagtcatcgc attttgactt ggtacggcta gcaatcataa tctctgtaaa tgtttcgcta
    17401 tcttgacaaa tctttgaaat agcaacttgg gcaacgcccc cacaaccaat aactagtaaa
    17461 cgactcattt ttttccttcc tcttcttcta aaatgtcctc aacatacttg ggcaacataa
    17521 aggctcccac gtgtaagttt gcagtgtagt attctgtgaa aagctggcgt tttttccagc
    17581 cttccttgtc aaaatctttg acagggtggt attttttcga tgcaaatcca aacaaccaat
    17641 agccagctgg gctagttgga atatgggcct gataaacccg actgattgga aaggcttgat
    17701 tgaccttgcg gtgcatgctt cggcaggccg actcatcctc gtcaaagaag ggactcccat
    17761 gctggtaaat catgatgccg tcttccttca gagctcgata actattgccg tagaattcct
    17821 tggtaaagag tccttccgta tggccaaatg gatctgtcgc atcgttgatg ataatatcgt
    17881 aatcatcttc gcagtttcgc aaaaagcgta gcccattttg gtagtaaatg gtaacacgag
    17941 gatcatctag ccctgcagca aagtctggga aatactcacg acagacctcg accaacatct
    18001 catccggttc cacaatatca atttgctcca gttcaggata gagggttaat acttgggcaa
    18061 caccgccgtc accaccccca ataaccaata ctttctttgg atttgggtgg acagccatgg
    18121 gaacgtgaac ggtcatttca ttgtagacga aatcatccgc atctgagaac aagacatggc
    18181 catttaaaat cagtattttc ccaaaagctg gcgtatccaa gacttcgata tcctgccatt
    18241 cactttttcc agcgtaaagt tgcttggctg ttctcagaga caatttgaca tctggagtat
    18301 gaacttcaga aaaccataaa tccatctatt tctccttata ttatatttag cgcagttagc
    18361 tactgccaaa gcccaagtgg tatacttgga ataagccact gtggattagt tcatttcctc
    18421 caatcgcttg acgatttccg aaaggctcta accacagctt ttgtttcaat tggtaatgag
    18481 tttgataacg catagacgtt ttatctcgtc taaggtaaca aggcaaaaag ttcgtggata
    18541 accaagtaga cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat
    18601 atcgctaaaa ataaacacga tgttacagcc ttgaatgttc aaggaaaaac tgttcttaaa
    18661 ccactcactt tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacag
    18721 ctcaaccaag actgtctcat cgctcttgaa gatactggac attatgcctt taatctactg
    18781 aacttcctgc atgaacaagg atataaagtt tacacctaca atcctttgct catcaaggaa
    18841 tttgccaaat cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc
    18901 gctcttaaac ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta
    18961 gaactaaaaa tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag
    19021 tacaatacac tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc
    19081 attcagaata tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg
    19141 caggatttga taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt
    19201 gccgtgctct aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa
    19261 ctattgactt ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg
    19321 atcttccgtc ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat
    19381 ttctcgtgta atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac
    19441 aaattctcca cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata
    19501 gaaggcttct tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc
    19561 cttcccatct cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat
    19621 gtcttggatg cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc
    19681 gatctgaatg tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat
    19741 tccctgagtg taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat
    19801 taactctttt gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc
    19861 ggatagctca atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga
    19921 aatatccaaa ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat
    19981 ctgacgaacg tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa
    20041 actcccacca gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga
    20101 aattggaagt ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat
    20161 catgccagct tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta
    20221 agtaggattg ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac
    20281 tcggtcattt tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata
    20341 gatgggaatg gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg
    20401 cagaataatc ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt
    20461 tgttccacca atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc
    20521 tgcatcacga ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac
    20581 atcaatgcct acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg
    20641 cttgtgacct ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcttc
    20701 ataaattggg gcttggtttt gatctaactc tttcaaaaca tactcctttc aatattttta
    20761 ggaccttatg aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc
    20821 tgctctgcaa tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg
    20881 tttcctaact ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt
    20941 gtgctttcac cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa
    21001 aagtaggctt ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc
    21061 tgcctgtccg taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt
    21121 tctaagcttt attactatat catgttttta agaacttgta aagtattttt tgataaaaaa
    21181 caaaaatata gtagattgaa actagaatag tacacttctg cttctaaaac attattagaa
    21241 atagatttta ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt
    21301 aaatgaaagt tctataatga agttagccac ccagccctcc taaaaattag atggttcaac
    21361 tagctgatag ctcttgtagg cataagaaaa cacctctgtg ttatacttgt tgttcaacca
    21421 caaacacaag aaaggcacag agatgcaaga caattatact acaaaagcca aacatttgac
    21481 aatcgatagc cgtcgcttaa tcgaaagatg gaaaaaagaa gggaaatcaa atagagaaat
    21541 tgcctctctg cttggaaaag ttcctcaaac tatccacact gaaatcaagc gtgggacagt
    21601 ccgacaatgt cttggaaaag ggcgcttcaa agaggtttat tctgccgact atgctcaaca
    21661 gtcttatgaa aacaatcgca agcgctcggt caggaaatca agcgtgacca aggaactaaa
    21721 ggaaaagatt ctccactatc ataaccaaaa attttcgcct gaaatgatgg tgatgg
//
LOCUS       DAVIME010000033        21111 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVIME010000033 DAVIME010000000
VERSION     DAVIME010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.033"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(244..462)
                     /locus_tag="VV588_001390"
     CDS             complement(244..462)
                     /locus_tag="VV588_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7083725.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(753..986)
                     /locus_tag="VV588_001391"
     CDS             complement(753..986)
                     /locus_tag="VV588_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEU7083726.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(1200..2831)
                     /gene="rlmD"
                     /locus_tag="VV588_001392"
     CDS             complement(1200..2831)
                     /gene="rlmD"
                     /locus_tag="VV588_001392"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU7083727.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2905..3879)
                     /locus_tag="VV588_001393"
     CDS             complement(2905..3879)
                     /locus_tag="VV588_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU7083728.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSAHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3953..4567)
                     /gene="pmp23"
                     /locus_tag="VV588_001394"
     CDS             complement(3953..4567)
                     /gene="pmp23"
                     /locus_tag="VV588_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU7083729.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4567..5541)
                     /locus_tag="VV588_001395"
     CDS             complement(4567..5541)
                     /locus_tag="VV588_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU7083730.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5549..6805)
                     /locus_tag="VV588_001396"
     CDS             complement(5549..6805)
                     /locus_tag="VV588_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU7083731.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6867..7298)
                     /locus_tag="VV588_001397"
     CDS             complement(6867..7298)
                     /locus_tag="VV588_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083732.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIC"
     gene            complement(7300..7902)
                     /locus_tag="VV588_001398"
     CDS             complement(7300..7902)
                     /locus_tag="VV588_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU7083733.1"
                     /translation="MMDRIRQELEKGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLSEISFEEA"
     gene            complement(7886..8725)
                     /gene="prmC"
                     /locus_tag="VV588_001399"
     CDS             complement(7886..8725)
                     /gene="prmC"
                     /locus_tag="VV588_001399"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU7083734.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8725..9804)
                     /gene="prfA"
                     /locus_tag="VV588_001400"
     CDS             complement(8725..9804)
                     /gene="prfA"
                     /locus_tag="VV588_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU7083735.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9801..10391)
                     /locus_tag="VV588_001401"
     CDS             complement(9801..10391)
                     /locus_tag="VV588_001401"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU7083736.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10515..10697
                     /locus_tag="VV588_001402"
     CDS             10515..10697
                     /locus_tag="VV588_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU7083737.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10834..12207
                     /gene="mnmE"
                     /locus_tag="VV588_001403"
     CDS             10834..12207
                     /gene="mnmE"
                     /locus_tag="VV588_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU7083738.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12254..13189)
                     /gene="dapA"
                     /locus_tag="VV588_001404"
     CDS             complement(12254..13189)
                     /gene="dapA"
                     /locus_tag="VV588_001404"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU7083739.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13245..14321)
                     /locus_tag="VV588_001405"
     CDS             complement(13245..14321)
                     /locus_tag="VV588_001405"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU7083740.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDMDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14663..14735)
                     /locus_tag="VV588_001406"
     tRNA            complement(14663..14735)
                     /locus_tag="VV588_001406"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14700..14702),aa:Thr,seq:ggt)
     gene            complement(14835..15344)
                     /locus_tag="VV588_001407"
     CDS             complement(14835..15344)
                     /locus_tag="VV588_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU7083741.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15342..15438)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15467..15898
                     /locus_tag="VV588_001408"
     CDS             15467..15898
                     /locus_tag="VV588_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU7083742.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15980..16357
                     /gene="mscL"
                     /locus_tag="VV588_001409"
     CDS             15980..16357
                     /gene="mscL"
                     /locus_tag="VV588_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU7083743.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16399..17493)
                     /gene="hemH"
                     /locus_tag="VV588_001410"
     CDS             complement(16399..17493)
                     /gene="hemH"
                     /locus_tag="VV588_001410"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU7083744.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            17647..18870
                     /gene="pepT"
                     /locus_tag="VV588_001411"
     CDS             17647..18870
                     /gene="pepT"
                     /locus_tag="VV588_001411"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU7083745.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18906..19238)
                     /locus_tag="VV588_001412"
     CDS             complement(18906..19238)
                     /locus_tag="VV588_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083746.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(19243..19536)
                     /locus_tag="VV588_001413"
     CDS             complement(19243..19536)
                     /locus_tag="VV588_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083747.1"
                     /translation="MSKANQLLERIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHFYLESNNGSDADF"
     gene            19501..19722
                     /locus_tag="VV588_001414"
     CDS             19501..19722
                     /locus_tag="VV588_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083748.1"
                     /translation="MDSFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19859..20068)
                     /locus_tag="VV588_001415"
                     /pseudo
     CDS             complement(19859..20068)
                     /locus_tag="VV588_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(20189..20331)
                     /locus_tag="VV588_001416"
                     /pseudo
     CDS             complement(20189..20331)
                     /locus_tag="VV588_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(20365..20505)
                     /locus_tag="VV588_001417"
     CDS             complement(20365..20505)
                     /locus_tag="VV588_001417"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU7083749.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(20549..21109)
                     /locus_tag="VV588_001418"
                     /pseudo
     CDS             complement(20549..21109)
                     /locus_tag="VV588_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6096 a         4402 c         3928 g         6685 t
ORIGIN      
        1 catcaataaa aatttgtttg ctaatatctc tttcttctga ttttgtttca aggattattg
       61 ctacatcatt catattttta ggtaaatacc aaccatctgg cttatctgaa tatcccttga
      121 agcctaattg attaaaagta gttatttgac cagtaccttg attgatgttt tcttcaactt
      181 cattaaagcc tatacttctc ttgcataatc cctaacttga tcttctgtcc ttaaagtcat
      241 tttctattcc tcgtcactaa aattatcttc aaaactaata atatcattag gagtgcaaga
      301 taaagcctta catattcttt ctaaattctt aaatgtaatt ggtttatcct ttcccatttg
      361 tgccataaca tttgttgtaa gtcctgccat agctattaca tctgttttct ttagtccttt
      421 ttttgctaac tgtatccata atggtttata gttaagtgcc ataatatccc tctttttttc
      481 ttcattagat ttatttaatt atagcataaa tattgatttc attcaatctt acattgattt
      541 agtgatttgt tttagagaat ttgttgtgtt attccgtcct tattttgcca taaattgttt
      601 taagtgggac ctcttatcct taccattttt acctcctaat tttgagtata aaaaagacga
      661 tagagttttt aatttctatc gtctgagatt tacatattaa attttcatca caaaataaga
      721 ctctttaaag aatctttaaa ttcattggta tgctaattac aatatccatt attaaaatgg
      781 atactataag cagcacacca actatttatt ttttgagttt taaactttgg tagaagtctt
      841 gaactcctta tatttacata actatttgcc tctataacta ttatgacacg aaaccaacaa
      901 gcaagttcaa gcacctccat atctttattc aaatgaggac taagatattc acaaacttta
      961 tcataaacct ctttatcttt tttcataaaa ggggcataca acttagcaaa tttatcctaa
     1021 aattttttgt tgcctttatc aatcatttca acactccttt aaatataaaa atgatcctat
     1081 caatctttat attgagccta ttttctaatt gataccttgc aagaaaggaa taatagctgt
     1141 tcctatacca agtaggaatg taataaatgc agaaagtcat atactgtcat tcttttctat
     1201 taaatcattt tgaagtgtct caaagcatcc atgatggctt cttctttttc aggtgtacac
     1261 tgtggaataa tttgtttatc ctttttagac ttgttgtaat gttctcgtaa ttctattcca
     1321 catttctttt ttatctgtgc aatatataat gtcgaaactt ttaattcaaa tttattccaa
     1381 acatattctt tgatttgagc atatgttgct ttgctctccg cacttgtcaa attcatctca
     1441 tccagctcaa tttcaacact tatgtgctta tcgacatcga gtttggacaa aagtgctacc
     1501 gtctcgacgt gatgcgtttg aggaaataga tccaccggct ggactttctt caattcatat
     1561 cccaattctt ggtagagttt gatatcacgc gccatggttg cgacattgca ggagatatag
     1621 gcgatgcgat cggctcctgt ttgggcgctt gctttgataa agctttctgt caagcccttg
     1681 cgtggaggat caaccaagat aacggttggt tgaatcccat ctttaagcca attcttcata
     1741 gcattttcag ctgtgtcaca gacatagtgg gcgtttgaaa tattgttcag ctgagcattt
     1801 tttttactat tctcaaccgc ttctggaatc agttcaacac cgtagacttc tttgacatgc
     1861 ttggcgactg ataaaccaat ggttccaata ccagaatagg catcaataat cacgtcatct
     1921 ttttttaact ctgcaaagtc aatggctgtt tgatagagtt tctccgccat ttcagtattg
     1981 acttggtaaa aggctgggcc agcgatttgg aagtcatttc ccaacatctg gtccgtaata
     2041 tagtcttgac cataaagagt gcgccactcc ttaccaaaaa tcgcattggt attctggtcg
     2101 ttgatatttt gcatgacaga cacaatctct gggaactgct tgataacttg ttcaatcaat
     2161 tggtcaacac gaaaaacttt tggacgagtt gtcaccaaaa cgaccatgat ttgtcctgaa
     2221 tagtgaccac gacgcaccac aagattccga atcaatccag actgttcctt ttcgtcataa
     2281 ggttttaaat caaaacgacg gagcaggtct cgaagagcta ctacgacttg gtcaatgaca
     2341 ggatcctgga taaagaaatc ttcaaggggc atgaggttgt gcgaattctt acggaaaaat
     2401 cctgtttcca agacaccatt cactcgacga acgggcacct gcgccttatt gcgatacttg
     2461 actggatgtt ccataccaag cgtttcagca acttctacat ctgcaattcc agcaatcttg
     2521 tagagactgt ccttgacttg cttggtttta aacttgagct gttctggata agaaaggtgt
     2581 cctaaatccg cgattcctga acgcaggtaa gccaaatcta gatcttgatt acggtgtggt
     2641 gactggacaa ggtatttttc aacttttcca aagccaatct ttttattgac cttgaggaca
     2701 cgcatgagaa ttttttcact cggtaaagca ttctctacaa aaaagaccaa accatctacc
     2761 ttggcaactc ctgccccttc atgggtcaag tcaacaattt caacttctac aatatcattt
     2821 ttctttaaca ttcttttctc tttctattgg ccgacaaaaa agacggcaac gttacggtta
     2881 ccatccatta taccatgaaa tttcttaaga accaaaactc ttgaagaagt tgacaagggc
     2941 ttgccagagg gagcttaaga agttaccacc gtcctctagc gccttatccg catcaaagtt
     3001 aaggttgata tttttaaaac tgtcgccagc ttgtgatacg atgctttgtt taaggtcatt
     3061 tagggtttta gtgaaatctg cattgctgag gatatcactc tttgagagat tcaaggcaaa
     3121 attgatgatg atattgatct ggtttcctgt tatgacctga tcaagtttgt aattttttaa
     3181 ggtatcttca acaatcttgc gtacatcttc ttctgtcaga tttcccttgc tttctttagc
     3241 tttggcgagt cctgacttga tatcagctag ggcaacgttt aatttattag catcatagcc
     3301 tgatttgtcc ttgttttcag cattgatatc tgacaaagcc tttagctctt cttgagccaa
     3361 atctttattg gcttgcggca ccttggctcc attagcttct agcgaatagt agatcccagc
     3421 caaagcactc tcacctgtaa ctggaatagg ggctgctaca gtgattttgg catgttccat
     3481 acccagcgtt actgctgcgt ttcggtacat atcctgagtc accttagtga tattttctgg
     3541 tgtttcaatc ttgacctcaa gtggcgattt gtcacctagc ttttgaatct tggctgatga
     3601 atacaactgt aagctagagt cattggccac attcatgatt ttagaataaa catcaggtgt
     3661 catggtcttg agttctttgg tatctgttga ggcattgtag cccagttttt taagagtttg
     3721 atttttttgg tcttcagata gggaggaacc taggacatat tcaggttgga cataggtttc
     3781 atcgataact ttttgaacat ctgttgctgc atgggcgcta ttcatagctg ttactgccca
     3841 caagaccgca gcactggtca gaaagagttt ctttctcata gggaatttcc tcctttactt
     3901 ttctagagta atatatctat cttaaagaaa acttataaca aaaacacctg gtctagccag
     3961 atgttgaaaa gagagtgaaa catttgatga tgtaaaggtt aagtcgtacc tgtctagaat
     4021 aataatagtt tcctccattt acatagagtt cagcaccgtg aaaaatggaa atggggtgaa
     4081 tataactata agtctttcca gtcgtattac caagcaaggg ggcaacagtc tcacgagagt
     4141 actgtttggc tagagccaag gtattttcct tgccattttg ggcgataaaa tcgatatagg
     4201 caggtccaaa attataggct tgaacagctg tccagatatc tacacccttc ttctgcgcca
     4261 gatagagatt gcctgtcaga gtttgaatgc cttgccgaat gctagaggca ttatcattga
     4321 tggtattggt ggaaccactt gcagactcac tagactgcat aacatcgcct tcttttcctt
     4381 ttgtttcagt ataaatcata gcaagcacaa gctcttcgtt tgctggggtg tctttttcac
     4441 tcaatatttc tcgcaccatg ggttgatagg tcatgacttg tttgacatct tgatgaacgc
     4501 ggtaagcttt atatccagca aaaaggaaga ctgctagtac aagcactctt cgaattcgtt
     4561 taaacattat ttactttgga tatcctcgat atttttgatt aagatagagt aggttccatt
     4621 ttcgttttgg ataaactcaa cagactcggc gtcttgatag acgttattgg gaacgatgag
     4681 ctcaattcca tttgataagg agagtttttg gttttcaaat ttctttaatt ggcgactggc
     4741 atcaatttca tcaaattgaa caggttctgg tacggcttct ttgacttggt caataaagct
     4801 caaacgagcc gtcagattgt tgtcaaaaag gtcattagcc aatttctcag gtgacaattc
     4861 attgctttct tctaggttgt tgaaaatagc tgatttgacc ttggattgaa attgaaaatc
     4921 atctgtgtta aaagattcag caattctctg ggctgttttt tccagttcct tgatagattt
     4981 tttaggagaa atcttaggag cgacagcaag aagattatct gaaaaatagt tcaaaaaagt
     5041 cccgttgtac ttgattcgtt tttcaatcag gtgatacttg ctactctgaa gattgaccac
     5101 caaggcctca tcagctcctg ttccaaatcc aggcaggtta ttctgagtta gcttgattgg
     5161 attatcaact tctcctccga ggtgggtcaa ggtctcccgc agggcaattc gcaagaaagc
     5221 gaaatgttct acaccttctt tagaaaattg aacaaaaatc aagtcattgg tcttgagatt
     5281 ttcagaaatg ctaaactcct ctttccagag attagccagc gttactgatg tctccaacaa
     5341 atcgtctgta atatgattga agaagggatt ttcttcttcg aaaatcccag tcttggcttc
     5401 atctgaatac acatgttcaa tttttttacg taggtattct tcgatttttg gagtaatatt
     5461 gagaaactta tctgctaaga acagctcggt atcatccgga ctgaactggt gaataatggc
     5521 tttcttaata taaatgtcca taaaagtttt attcctcgta taatgggaag gcatctgtca
     5581 attctttgac tgcacttctc acttcttcta atacagcctc attttctgaa ttcttaaggg
     5641 ttttaatgat gagttcagcc actttgcgac tttcttcttc accaaatcca cgtgcagtaa
     5701 tagctgctgc tccgatacga atcccacttg tcttgaatgg tgacaagctt tcgtaaggga
     5761 ttgagttttt atttaaggta atattgactt catccaacaa gttttgagca actttgccgt
     5821 tttctacaac tttagtcaca tcaacaagga agagatggtt ttcagttcca cctgaaataa
     5881 tacggaaatc agggtcttgc aagaagacat ctgccatagc cttgctgttc ttaattacat
     5941 tggcagcata ttccttgaag gctggatcca aaacttcttt gaaggaaact gccttagccg
     6001 ccacaacatg ctctaaagga ccgccctgaa tacctgggaa aatagctgaa ttgatttttt
     6061 tagcaagttc ttcgtcattg gtcaaaatca aaccaccacg aggtccacga agggttttgt
     6121 gggtcgttgt tgttgtgata tgagcgtatg gaactgggct tggatgaagg ccagccgcaa
     6181 ccaagccagc gatatgggcc atgtccacca tgagcttcgc accgacagca tctgcgattt
     6241 cacggaattt tgaaaaatcg ataatttgag aataggctga agcaccagct acaatcagtt
     6301 ttggttttac ttcttgggct tgtttcaaga tagcatcaaa gtctaagagt tccgttttag
     6361 gatcaacact ataagaaaca aagttgtagg tttgaccaga gaagctaaca ggagccccat
     6421 gagtcaaatg accacctgat gccaaatcca ttcccataac cgtatcacct ggctcaatca
     6481 aggacatgta agccgcacag ttagcttggc ttcctgaatg tggttgaaca ttggcaaatt
     6541 tagcaccgaa aatttctttt gcgcgttcaa tagcaagagt ctctacaacg tctactacat
     6601 cagttccacc ataataacgg cgtcctgggt aaccctcggc atatttattt gtcaagatag
     6661 acccttgagc tgccataaca gccttggaaa ctacgttttc cgaagcaatt aactcgatat
     6721 tattttgttg gcgttcttct tctttggcaa tagcattcca gagatcagca tcatatgctt
     6781 taaaatcatc tttgtcaaaa atcataggtc ttctccttta ttgtgtgact agtccattag
     6841 tttgatttta caataagaaa atcaaactaa cagatgcgaa taaaccgttt ctgcatttta
     6901 tcacaagtat agccaacttt ttcataaaat gcatgagcac ccagacgatg attggcagaa
     6961 tttaagcgga taaacccata accacatctt tttgcttctt cttccaaccc ttgtagtaaa
     7021 cttttaccaa taccttgacc ttgcgcttga ggtgaaactg ctaaagctaa gatattaaat
     7081 cctgctttgg aatagagtga ttcgtaaact tcagcgtgga catatccaag taagacatga
     7141 ttagctgcat cctcatagcc aagtaggaaa tgatgggaat cctgagacag tctagctagt
     7201 tggctagccg tttcctctgg actaaaagta taacccaaag cctcttggtt gatgtcacat
     7261 atcgctttca catctgtttc ttgcaaatct cttagcattt caagcctcct caaaagaaat
     7321 ctctgacaac cgagcaagaa tatcttctcg tttaattgcg ccttggcgta agattttcac
     7381 cttgtctcca gacaaatcca caatagttga atcctgtcca gttagaaaag catcgtcttc
     7441 cagacccaga acctcttggt caaaatcctt cagaatttgt tcaaaggtta caccacttgc
     7501 ctgacctgag atattggcag acggcccaat caagggacct gtctctcgaa ttaaatccag
     7561 tgtgataggg tgactgggca tccgaaatcc aatagttgca aggtcagaat ttacccaata
     7621 gggaactcgg tcattggctt cgagaataat ggtcaaggga cctggcaaaa aggtctctac
     7681 aagtttttgt agataagctg gctgattctt tgaaaagtgc aagatgtcct cgaaagaggc
     7741 gatattgaga ttgagtgcct tatctctagg acgacgtttg agttggtaaa catggtcaac
     7801 tgctttttca tctaaggcct tggaaaaaag accataaaca gtctctgtag gtagaacgac
     7861 agctccaccc ttttccaact cttgtctaat cctgtccatc atcaaccaca accatcctat
     7921 tttgaccaaa ttggtctttg agtgttcgaa ctcttttttc aggaagatgt tttctaaaaa
     7981 gttcgggaac actttgacct tgcttgtatc caatttcaag gtaaatctta ccaccatcct
     8041 tgagatagtc ttttgcatct tccgcaattc tacagtaaat agctaggcca tcctcgtctg
     8101 caaagagagc tagatgaggc tccgaatgca aaacattcaa gcctacctct gactcatctt
     8161 cacgagagat atagggtgga ttggatacaa ttatatcata tttttcagaa atttctgcaa
     8221 aacaatcaga ttttttaaaa aatatattaa gattttgatc gctagcattc tctgatgcaa
     8281 gctctaaggc ctcttgagaa acatctgctg ctgtcactga ccaatctggt ctattttttg
     8341 ctagagcgag agcaatagct ccactacctg ttccaatatc cagaactgag agattcgtct
     8401 caagattttc agttagaata agctccacta actcctctgt ttctggacga ggaatcaaaa
     8461 cccgttcatc cacctttaaa tgcattccat aaaaatctgc ctgtccaatg atgtactgag
     8521 ctggcttgtg agctgctagt tgctggtaaa tatcttctac aaattgtttt tcttcctctg
     8581 ttgtcacctc ctgctggagg gcaaaaataa agtctgtaaa agatagattt ttcagactac
     8641 gatagacaaa agagaggctt tccgcttcct ctccttgtct tatcaactct tcttcaaaat
     8701 ttgaaaataa ttgagctaat ttcattattt gtttaattct tctagttttt gtgtttggtc
     8761 ataaagcacc aaggcatcca caacttcgtc caatttacca gacaaaatcg tatctagttt
     8821 ttggagggtc aagccgatac ggtggtctgt gacacggttt tgtgggaagt tataagttcg
     8881 gatccgttct gaacggtcac cagtaccgat tgtcgactta cgctcagcgt cttgttcatc
     8941 ctgagcaatc tgagcaaagt ggtcagcgac gcgtgcacgg ataatcttca tagccttctc
     9001 gcggttcttc tgctgggtac gttcttcctg catctcaacc ttgatattgg ttggcaagtg
     9061 aacgatacga acggcagtcg caaccttatt gacgttctgt ccaccagcac cagaggcgtg
     9121 atagatgtcg acacgaaggt cttttggatc aatgtcgtat tcaacctctt caacttctgg
     9181 cataacaaga actgtcgctg tcgaagtatg aacacggcct tggctttctg tcacaggaac
     9241 acgttgcaca cggtgggcac ctgattcata cttaagctta gagtatacag actgacctga
     9301 aaccatagca accacttctt taaaaccacc gacaccattc atagaggctt ccatgacttc
     9361 aaagcgccaa ccttgggctt ccgcatactt ttggtacata gttagcaaat ctccagcgaa
     9421 aagtgccgct tcgtctccac cagctgctcc acggatttca aggatgatat tcttgtcatc
     9481 gtttggatcc tttggaagga gcaaaatttt cagtttttct tcatattctt ctttttcagc
     9541 cttggcatct ttgagttctt gcttggccaa ttcttccaag tccgcatctc cgcctgattc
     9601 cttaatcatc tcttcggcat cgacgatatt ttgaaggact tgtttatact cacggtaggc
     9661 tattacggtg tcacgattgg aagcttcttc ttttgaaagc tccataaaac gcttggtgtc
     9721 tgaaacgaca tcagggtcac tcagcaattc tcctagttct tcataacggt cttctacagc
     9781 ttgtagttga tcatagatgt tcatttttct tcattctcct tattgatttc aggggcaaaa
     9841 taatgtttac ggcaaaccga gatataggtt tcattaccac caatctggat ctgttctcca
     9901 tcgtaaacgg gcagtccatc ctgtgttcgc aacaccatgg tcgccttttt cttgcaatac
     9961 tgacagatgg tcttgatttc gtcaatcttg tccgctaaaa gcaagagata tttggaacct
    10021 tcgaacaatt cattgcgaaa gtcatttttc aagccaaaag ccatgacggg tatgtctaac
    10081 tcgtccacaa cacgagctag gtcataaaca tggtggcgtt tgagaaactg ggcttcatcg
    10141 accaaaacac agtaaggttt ttctggtagg tctcggatat agccaaagat atccgttgtt
    10201 tcctcaatcg caagggcagg gcgtttcatg ccaattcgac tcgacacata gccaacaccg
    10261 tcacgcgtat ccagagccga ggtcataatg acaacacctt ttccttgctc ctcgtagtta
    10321 taggccactt tgagaatctc aatcgtttta ccagagttca tggtcccata acgatagtac
    10381 aactgtgcca tgtttcttgc ttcacgtcca tttctaaatt tttgctacat tctagtatat
    10441 cataattttc ttaagcttta aacggcaaaa tgtggtaaaa tagaagaaat caaaaactag
    10501 tggaggaagc tattatgcca tttgtacgca tcgatttatt tgaaggacgc acgctcgagc
    10561 aaaagaaagc tcttgctaag gaagtaacgg aagcggttgt tcgcaacact ggagcacctc
    10621 aatctgctgt ccatgtcatc atcaacgaca tgccagaagg aacttacttc ccacaagggg
    10681 aaatgcgtac caaataagct agcttaagca gaattgctta ggctttttca atctccaagt
    10741 agcattcatt gaagaaatat cctaaatttg ttacaatttg aaaagaaact tggagaattt
    10801 ccaagaaaag agcaattaat taaaggaaac attatgatta cacgtgaatt tgataccatc
    10861 gctgctatat ctactccact aggtgaaggg gctattggta ttgtccgcct gagcggaaca
    10921 gacagttttg ctattgcgca aaagattttt aaaggaaaag acttgaacaa ggttgccagc
    10981 cacactctca actacggtca cattatcgat cctctgactg gtaaagtcat ggacgaggtt
    11041 atggttgggg ctatgaagtc tccaaagacc ttcactcgtg aggatattat cgagattaac
    11101 acccacggtg ggattgcggt gaccaatgag attctccagc tagctatccg tgagggagct
    11161 cggttggcag aacctggtga atttaccaaa cgtgcctttt taaacggtcg cgtagatttg
    11221 acacaggccg aggcggtgat ggatatcatc cgcgccaaga cagacaaggc catgaacatt
    11281 gcagttaagc aattagacgg ctccctttct gacctcatta acaatacccg tcaagaaatc
    11341 ctcaatacac ttgcccaagt tgaggtcaat atcgattatc ctgaatatga tgatgttgag
    11401 gaagctacta ctgccgttgt ccgtgagaag actatggagt ttgagcaatt gctaaccaag
    11461 ctccttagga cagcccgtcg tggtaaaatc cttcgtgaag gaatttcaac ggctatcatt
    11521 ggacgtccca acgttgggaa atcaagcctt ctcaacaacc tcttgcgtga ggacaaggct
    11581 atcgtaacag atatcgctgg gacaacacga gatgtcatcg aagagtacgt caacatcaat
    11641 ggtgtacctc tcaaattgat tgatacagcc ggtattcgtg aaacagatga catagtggaa
    11701 caaatcggtg ttgagcgttc gaaaaaagcc ctcaaggaag ccgacttggt tctactagtg
    11761 ctaaatgcca gtgaaccact gactgcgcaa gacagacaac ttcttgaaat tagccaagat
    11821 accaatcgca ttattctact taataaaacc gacctgccag aaacgattga aacttcgaaa
    11881 ctacctgaag acgttatccg tatttcagtc cttaaaaacc aaaacatcga caagattgaa
    11941 gagcgaatca acaacctctt ctttgaaaat gctggcttgg tcgagcaaga tgctacttac
    12001 ttgtcaaacg cccgtcacat ttccctgatt gaaaaagcag ttgaaagcct acaagccgtt
    12061 aatcaaggtc ttgagctggg gatgccagtt gatttgcttc aagttgactt gactcgtact
    12121 tgggaaatcc tcggagaaat cactggggat gctgctccag atgaactcat cacccaactc
    12181 tttagccaat tctgtttagg aaaataagaa aaatccatga tccttcattc ggtcatggat
    12241 tttattgtct ttattagtaa tctggtctta agacccctgt tacagttgcc ttagttgctt
    12301 cgtagtcgcc atctacgaca accttgataa tgcgtttggc atcttcttct ggtgctggaa
    12361 caagaggtag acgagtgggt ccagcttcaa atcccatata gttaagaact gccttaactg
    12421 gagcaggact tggataagag aagagagcat taaccttagg aatgaattta cgctgaattg
    12481 ctgcggcttt cttcatatcg ctttctgcaa tggcagtaaa catctcgtgc atttcatccc
    12541 catttgtatg agaggcaaca gaaataaccc catccgcccc aaggttcatg gcatggaaag
    12601 catctccatc ctcacctgta taaatcaaga actcttcagg cttgtgctca atcaagtaag
    12661 ccatattagc caagctagta cattctttga caccgataat atttggatgg tcagccaaac
    12721 gaagcatggt ttctggagtc aattcgacaa ctacacgccc tggaatgtta tagataataa
    12781 ttggtaggtc agaagcatct gcaatagcct taaagtgctg atacatccct tcttgagaag
    12841 gtttgttgta gtaaggaaca atagcaagcc cagctgcgaa accaccaaat tccgctactt
    12901 ctttgacaaa ctcaatagag tcacgcgtat cattagtacc tacacccgca atcaaaggaa
    12961 cgcgtccatt gacaaccttt tgtacagccg caaacaactc caactcctca tcgtgggtca
    13021 aagttggact ctcagcagtc gttcctgcga gaagaattcc atccgtatga tgggccaata
    13081 aatgctcaat caaggctgga atagcatcaa agttaatgga accatcctca tggaaggggg
    13141 taataaaggc tgtaatgatt ttacattctt ttaaatcttg ataagacacg aaaacacctc
    13201 tctatttcaa agaaggagtt catctgaact cctaaacgat atgactattt taattcaaat
    13261 ttcaattcgg ctgttggacg aaccaatcca cgttcatgaa gagtttcagc aatctgaact
    13321 gagttccaag cagcaccttt gagaaggtta tctgaaacaa cccacatgtg aattcctttt
    13381 tctgcatcca tgtctttacg gatacgacca acaaaggtat cacgcgaacc aactgcattg
    13441 atagcttgag gatagatttg atgagctaca tcatcttcaa gaacagcacc tgggaaggct
    13501 gcgatagctg cttttacttc ttcgattgga gccacttctt ttgtttcgat ataaacagac
    13561 tcagagtgag ctgacaagac tggaatacgc acacatgttg cagatactgc aatgctatca
    13621 tcttccataa ttttcttagt ttccttggtc atcttcatct cttcgtacgt gtaatcatta
    13681 tcagtgaaaa catcaatttg tggaagagcg ttaaaggcga taggataatg tttcttgtca
    13741 ccacctgaag gcaagatttc cgcatgcaaa tcacgtggtt tcacaccatc attcaagact
    13801 tcacgaagtt cacgttgtgt ctcaagaatt gctcccatac cagcacctga aacggcttga
    13861 taagttgaaa caatgatacg gtccaagccc catttttggc gaaccggctc aagagccacc
    13921 atcatttgga ttgttgaaca attagggcag gcaatgattc cgttgtgagc atcaagtgca
    13981 tgagcattga cctctggaac aaccaaagga acatctggat tttgacggaa ataagatgta
    14041 ttatctacta ctaccacgcc agcttttact gcgtatggtg catacttagc tgatgtagaa
    14101 ctacctgctg aaaagagagc aatatcaact ccttcaaaag ctgtttcagt cgtttcttca
    14161 attgtaatat cttgatcttt aaatttcaat gacttacctg ctgaacgtgc agaagcaagg
    14221 taacggattt tatcgattgg aagtgttgat tcttccaaca tttttatcat ctgagcaccg
    14281 acagcacctg tcgcgccgac tacagcaact gtatatccca taaataacct ctttcggaat
    14341 tttctaaaaa tttctataat agaagtatta tactactttt tccatgaatt gcaaagcttt
    14401 ttcattattt tttggaaaat aaaaatccca gtcgctagac tagggactaa gaggcatctt
    14461 catgtgatga gcaggttcac acaactcatc aaggtccgct cctgcgttat gacctcctta
    14521 tgctcaatag tagtccgaag actacctatc gactcatcgc atattctata ttactagaga
    14581 tacttgattt tgtcaataag aaattttttc gatcgagtat aacaaaaaac tcttgtattc
    14641 aagagtttcc ctatacatat catgctaatt gccgggattg aaccggcgac ctcatcctta
    14701 ccatggatgc gctctgccaa ctgagctaaa tcagcttact taagaagtat actataatca
    14761 gaaaaacttg tcaagtttcc ttagaaattt tccataggaa aaagccaggt aagaactacc
    14821 tagcttatct tcttctattt acttaaatca attcgacgac caattttacc aataataatc
    14881 gctccaataa tcaatgaagc aaattcaccg attcctgttg taaaccaagt aaggaagaat
    14941 ggtaattctg ctacaatatt taactctgca gcgatagtaa acatggaaat tgaaaagagg
    15001 attgaaaaga agaaatgatc ttttcgaatc aatccgttaa agaggtaatc cttgctatat
    15061 tttgcaaaaa gccaaacacc taaactgagg aatactaagg ttgaaccacc accaacaaag
    15121 acatctagca gtccgaagct aaagaaatta gcaatcatac aaccgatggt aactccgatg
    15181 atgtacttag gattgtaaaa agccataaag ttcatcattt ctgaaatacg aaactgataa
    15241 gcaccatagc tgatggcatt taggggcggt gtgacagtca aaacgacgta gatagcagcg
    15301 acgattgcaa tatctgcaac atcacgaata gttaattttt tcatcttttc tcctttggcg
    15361 gttatccgcg tgtaatatgc ttggtgaaag aagctaagca ccaagggttg attcattcaa
    15421 ccttactagt atagcacaat agcctgcttt atgctatact taaagcatga aaaaacctat
    15481 tcaaaaattt tttaacaatg aaatcttagc ctatctcttt tttggccttg cgacaactct
    15541 agtttcgatt ctctcacgac tagtcattta tcaactaagt catcaggaac tccttgctac
    15601 ggccttggca aatattatcg gtatcttatt tgcctttatc acaaatgata cgattgtatt
    15661 taagcaaaaa aagaaaaata gacttatccg tttagtgaaa ttttctcttg ctcgcctttc
    15721 tacttttctg ttagacttgt ttttaacttt tctctttgta acccaatttc ctcacatcat
    15781 agggcaattc gtaactgaaa acattgataa gataaatgct attgaaacaa taattgcaca
    15841 aatattcatt attatcatca attatatctt gagcaaggtc tatattttta gaaaataatg
    15901 ctccatttat gagcctttta attgccttct ataatgattt aggatacaat gaaacacgaa
    15961 acattgaaag gaaaacagta tgttaaaaaa tctaaaatcg ttcttgcttc gaggaaatgt
    16021 tattgacctt gctgtcggtg ttgtcattgc ctctgctttt ggtgctatcg ttacttcact
    16081 tgtaaacgac attatcactc ctcttatttt aaatcccgct ttgaaagctg ctaaagtcga
    16141 acgtatcgct caactttctt ggcatggagt cggctatggt aactttttaa gtgctattat
    16201 caattttatc tttgtgggta ccgccctctt ctttattatc aagggcattg aaaaagcaca
    16261 gaaactgact ggcataaaga aagaaaaaac tgccgaaaaa aaaccaaccg aattggaagt
    16321 ccttcaagaa ataaaagctc tccttgagaa aaaataatcg attaaaagga tctagcgcaa
    16381 agctaaatcc ttttttcttt actctttggg taacttgcct gctttttcaa gcattttttt
    16441 gataagataa ggcatcttaa tattctcccg cccttttttc tcaatcagtt ttttcacaaa
    16501 ttctggcatt tgtaaatctt cagattcagc taaaatgttt ttcgtctcgt ctgaaggaac
    16561 taactcatca aaggtctctt cttctgggag aaattcctta aactcttgat tttcattgac
    16621 tctaactgta ttgaccaaag catcaatcaa acgagaatct gtatttggca ttggtggacg
    16681 atggtagttt accccaaatt cctgacataa atcataacat tccacatcat tgtcaaacaa
    16741 gacctcaata tgctcactga tgaaactaat aggtacaaaa atataatggt ctggatgttc
    16801 tgtctgttct ctgagatact ccaaaacatc tggtttaatc catggaatac caatatcact
    16861 ctcactctgc caagtgttgg tatattgttc tgaactcaag cccagttttt cagcgactag
    16921 cttgctattt tcgaaaattt ggtctatata aggatctcca aagtccaagg caaaaatagg
    16981 cacactatgg gctgaaaaga tgactttaaa gctgtcttgc tttacttctt cttttaaaat
    17041 cttagcaatt tcatctgccc aatagtttaa gagcgcttct tcctgatacc agtccttaat
    17101 gaccaaaaat tgaatttgtt tgctttctaa aaatttttca tagcccatga cagagtagaa
    17161 agaataatgg ggctccaaaa tcaagcaaat acactgttca attccgtctg cttccatttg
    17221 accgatcaca tctggaataa agggactgga aaacttatta gcaaagtaga cactgtattc
    17281 attccccagc ctagcttcta ccaaggcaac ctcttgacgg gtaatttttt gcagaggcgt
    17341 gcctccaatt cgtacataat tatcatagag agtctgaatc tcgtggtctt ggggtctcat
    17401 cccacgacga atatttgtga aaaaatcagc tacaccttca aaggtaatct cttctggtga
    17461 accgaaggtc atcattaaaa ttgctttttt catgactgct tccttgtgat gtttttatca
    17521 agtttatttt atcattaatt catcgataag taaacgctag catagggaca ttctcaatct
    17581 tctgtctttt gtttttctct tctttctatg atacaatgga aaaaataaat tcaaaaggag
    17641 ttttttatga cttatccaaa tctcttggac cgcttcttaa cctacgttaa ggtcaacacg
    17701 cgctctgatg aacactctac tactactcca agtacacaga gtcaggttga cttcgcaaca
    17761 aatgtcctaa ttcctgaaat gaaacgtgtt ggactgcaaa atgtttacta tctaccgaat
    17821 ggttttgcta ttggaacctt gccagccaac gatccgtctt taacacgtaa gattggtttt
    17881 atatcgcaca tggatactgc tgattttaat gctgaaggag tcaatccaca ggtaattgaa
    17941 aactacgatg gtggtgtgat tgaactaggg aattctggtt tcaaactcga tccagctgac
    18001 ttcaagagtc ttgaaaaata tccaggacaa acgctcatca caacagatgg aacaagcttg
    18061 ctaggcgctg atgacaaatc aggaattgct gaaattatga cagccattga atatctaact
    18121 gctcatcctg aaattaagca ctgtgagatt cgtgttggtt ttggtccaga tgaagaaatc
    18181 ggtgttggtg ccaataaatt tgatgcagaa gattttgatg tggattttgc ctacactgtt
    18241 gatggtggtc cactaggtga acttcagtac gagactttct cagccgctgg tgctgaattg
    18301 catttccaag gccgtaatgt ccaccctggt actgccaaag ggcagatggt caatgccctt
    18361 cagctagcaa ttgattttca taatcaactt ccagaaaatg accgacctga gttaactgaa
    18421 ggttaccaag gtttttacca tctaatggat gtgacaggta gtgttgagga ggcgcgtgca
    18481 agctacatca ttcgtgattt tgaaaaagat gcctttgaag cgcgtaaagc atccatgcaa
    18541 tctatcgctg ataagatgaa tgaagaactt gggagcgacc gtgtcactct caacttgaca
    18601 gaccagtact acaatatgaa agaagtcatt gaaaaagata tgactccaat taccattgct
    18661 aaagccgtta tggaagatct aggtatcacg cctattatcg aaccaatccg gggtggaaca
    18721 gacggctcta agatttcctt tatgggaatc ccaactccga atatctttgc aggtggcgaa
    18781 aatatgcacg gacgttttga atacgttagc cttcagacta tggaacgtgc agttgatacc
    18841 atcattggca tcgtagctta taaaggctaa aaagacgagg tagctcagct acttcgcctt
    18901 tctttttatt ctactggttt ttcttgattt ccagtagttg tagaagattc tgttgtttta
    18961 ttttctgaag ttgattcagc aggtttagaa tctcttgtat tgcttggttt gttttcgtcg
    19021 ctagcagttt caatgttaga ttctgcagtt gcgtttggtt ggttctcagc actggtgtta
    19081 tcaccatttg cttcagcatt tcttgctgga cttgtttctt cacttgcgct agcttttgac
    19141 tggatttgat gattcaaaac tagaatagct tttgtcgatt caagtaaagc tgttttgtct
    19201 ttactattag cagaaagttg atctaataat gcatccacct tatcaaaagt ccgcatcaga
    19261 tccattatta ctttctaaat aaaagtgaag cgacatgaga atatcgtaga gtttttgata
    19321 gagtacaagt gtctgaggat cttgctcagc attttccttt tcttgttgaa gggcgctagc
    19381 gatacgagtc aagacatctt ttacctgact gtttacttca tccaagtctg catcagcctt
    19441 gtttgtggca gcttttagat tttctacttc ttctgccaaa gattgtctga ttccttcttc
    19501 atggattcgt tccaagagtt gatttgcctt gctcaaaaga ctttctactt cttccttgct
    19561 atctgtcgca gattattggt tgctatctac catgtactcc taaaacagga gagttataat
    19621 ccaagattac aaggccttac agaaataaga aatccagata agacaatgtt cgtccaagac
    19681 gctattcgct tcgcacagca gcacggattc aatatgcttt aattttaaag tttaggtgtc
    19741 aagacctctt tttagtgtgc ccaaaattta gagaagtaat caatcaacta acttttattt
    19801 ttttcaaact ttcagtaaac tgacctaaag ctaactcaat ctgtctttgt tcgataggct
    19861 tgtctttgta gatgcttctg ctatcagcta gaagttgatc tacttttgcc aagactgcct
    19921 tctcatcaaa agttccaggt tgatagttgg attgcaggga tggaatcttg tttttcaaag
    19981 ccgcttcata tcccttagtt tgaaccttga tgtagtgatt gtggtcgcca cgaggaatca
    20041 caaaaccttc tgaatcttca cttataattc gattggcatc aaaaccatga ccatcttctt
    20101 cctcatggtg gacatgtagt gacggattac ttaatacaga actagaagaa cttcctacct
    20161 cttccgtgtt agagtgtgat gggggattgt taagagatga cttaggaata tagtgatagt
    20221 gaccccatgt cttactatat aagcatcacc tgtatctctg acaatatcat tagggttaaa
    20281 gacataacca tcatctgctg cagaaacacc attattcggt gtcaccgaca aagattgact
    20341 gagagctgta gtattctctg ataattatac ttttgcagct gctaattcac ctgccgacaa
    20401 gtcactctca ggaatgaaat gatagtgacc accatgtggt actatagtag attgaaatag
    20461 aatatgagca aattgataag gggattttaa agtaatttct aacaatgatt tagaaactat
    20521 gatgtgctat tctaaattca actcactata tataaccatc atcggtagta taacgtccct
    20581 gtaattttac tacagatact tctgcactag ctcctttatc gtctttacca tgttcttgtt
    20641 tttggcgatt gatttcatct tttattcgta cattttctgc atgagcttga tctttaaggt
    20701 aaacataata ctttccatct accttaataa tatatcctcc cttaacctaa ctgacgatat
    20761 cttgatcttt cggctgatag ttgggggctt tcattaatag ctcttcacta aagagcgcat
    20821 ccaaaggaac tttaccatta tagcagtgat aatgatcgcc atgagaagtt acataacctt
    20881 gatctgtaat cttaataaca atttgttttg cttgaattcc ttctttttga ctaacctagt
    20941 ctggagtcaa attttcagtc ttcttagtgt ctttattact gtttacatat gaaacacgat
    21001 ttttatctgt attggcctgt tagctatgtt ggttcagagc ataaacacac agacttaagg
    21061 aaaggataac aacagatcca gctgctatat atttcttttt aaatttcata a
//
LOCUS       DAVIME010000034        20456 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVIME010000034 DAVIME010000000
VERSION     DAVIME010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20456
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.034"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            83..880
                     /locus_tag="VV588_001419"
     CDS             83..880
                     /locus_tag="VV588_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU7083750.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VV588_001420"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VV588_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VV588_001421"
     CDS             2383..3657
                     /locus_tag="VV588_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU7083751.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VV588_001422"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VV588_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU7083752.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VV588_001423"
     CDS             4786..5088
                     /locus_tag="VV588_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU7083753.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VV588_001424"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VV588_001424"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU7083754.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VV588_001425"
     CDS             5962..7302
                     /locus_tag="VV588_001425"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU7083755.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VV588_001426"
     CDS             7280..7492
                     /locus_tag="VV588_001426"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU7083756.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VV588_001427"
     CDS             7489..8364
                     /locus_tag="VV588_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU7083757.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VV588_001428"
     CDS             8357..9172
                     /locus_tag="VV588_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU7083758.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VV588_001429"
     CDS             9165..9596
                     /locus_tag="VV588_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU7083759.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VV588_001430"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VV588_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU7083760.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDMTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VV588_001431"
     CDS             11272..12000
                     /locus_tag="VV588_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU7083761.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VV588_001432"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VV588_001432"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU7083762.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VV588_001433"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VV588_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14359..14835
                     /locus_tag="VV588_001434"
     CDS             14359..14835
                     /locus_tag="VV588_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7083763.1"
                     /translation="MVLDYFFDKNLVLCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMNFFTGNGHLEDLSKISEPEKLYAYIDEAIA"
     gene            14873..15175
                     /locus_tag="VV588_001435"
     CDS             14873..15175
                     /locus_tag="VV588_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7083764.1"
                     /translation="MIKILAACGAGVNSSHQIKSTLEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSAPVFDNIRLPAKQNMV"
     gene            15183..15986
                     /locus_tag="VV588_001436"
                     /pseudo
     CDS             15183..15986
                     /locus_tag="VV588_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            16035..16499
                     /locus_tag="VV588_001437"
     CDS             16035..16499
                     /locus_tag="VV588_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU7083765.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            16656..17081
                     /gene="lacA"
                     /locus_tag="VV588_001438"
     CDS             16656..17081
                     /gene="lacA"
                     /locus_tag="VV588_001438"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU7083766.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            17112..17627
                     /gene="lacB"
                     /locus_tag="VV588_001439"
     CDS             17112..17627
                     /gene="lacB"
                     /locus_tag="VV588_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU7083767.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            17638..18567
                     /locus_tag="VV588_001440"
     CDS             17638..18567
                     /locus_tag="VV588_001440"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU7083768.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            18569..19549
                     /gene="lacD"
                     /locus_tag="VV588_001441"
     CDS             18569..19549
                     /gene="lacD"
                     /locus_tag="VV588_001441"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU7083769.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            19955..20431
                     /locus_tag="VV588_001442"
     CDS             19955..20431
                     /locus_tag="VV588_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083770.1"
                     /translation="MNVDGNKFYNVSVSEDIVNAGQILEDYFYVDKFGNINLKGTPEE
                     LAKNIGISVQEASLMYEAVKELPNVYERGPVGFRFNLGPQVRGMGGWAAGAFATGYAG
                     WHLKQFAVNPVTSGFVAVISGAIGWAVKTAVENYWTVAVATVEVPFVNLVYTIDLP"
BASE COUNT         6263 a         3650 c         4680 g         5863 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aaacttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccttca
     2341 tgcatgatat aatggttaca gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gcggagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc ggacaagtcc gatttcttat
     4141 gatggccaac ttgctcgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaaca ccaatcggtc
     4921 atggccgatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagat caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgcctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgctaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattttt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatatgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tctcaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatggag aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 gggattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggttttc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc aacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgct ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcatcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aaccatgttt tgagctgact
    14101 tcgtcagtct tatctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaag agacaaaaaa
    14281 gaacagaaag taattaacaa cgatttcata tagtgttata cttatggcat aaagttaatg
    14341 gaaagaaggg aaaaccttat ggtattagat tatttctttg acaaaaacct tgtgctttgc
    14401 ttagaagcgg ataatcaaga acaactcttt gatcaggtag caagcttgtt ggaagaacga
    14461 gaaattgtca ctcctactta tcgtgaagcc ttgatcacgc gtgaaaagtc atttccaact
    14521 ggtttagata tggaatttct aggaaaggac ttgccaaatg tagcgattcc tcacacagat
    14581 attgttcata atctagctga gaaagtggtg gttgttcgat tagaaaaacc agtaactttt
    14641 cacaatatga tagctcccga taaggaagta gaagtatccc tactcttctt tatcattaat
    14701 aattcaagtt caagtcaaac gaacattctt gctcagttga tgaacttctt cacaggaaat
    14761 ggacatcttg aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttatatagat
    14821 gaagcaatcg cttaatcttg tctattaaaa aataaaatcg gaggaagtct atatgattaa
    14881 aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtactctaga
    14941 agaagaactt tcaaaccgtg gttacgatgt tcactgtgat gcagtcatgg tgaaagatgt
    15001 aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa cagatcttgg
    15061 ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattttgta tcccagcaat
    15121 gagcgctcca gtatttgaca atattagact ccctgcgaaa caaaatatgg tatagtagtt
    15181 ctatgaatga tgaagcaagt aaacaactaa ccgatgcacg atttaagcgt cttgttggtg
    15241 ttcagcgtac cacttttgaa gagatgttag ctgtattaaa aacagcttat caacttaaac
    15301 acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ccttcttatg gccactcttc
    15361 aatatgtgcg agaatatcgc acttatgaac aattgcggct gattttggta tccacgaaag
    15421 caacttactc cgtcggagcc aatgggttga agtaactctt gttcaaagtg gttttacgat
    15481 ttcaagaact cctctcagtt ctgaggacac ggtaatgatt gatgcgacga aagtaaaaat
    15541 caatcgccct aaaaaaagaa ttagcgaatg attctggtaa aaagaaatgc cacgctatga
    15601 agtctcaggc gattgtcaca agtcaaggga gaattgtttc tttggatatc actgtgaact
    15661 attgtcatga tatgaagttg ttcaaaatga gtcgcagaaa tatcggacaa gctggaaaaa
    15721 tcttggctga cagtggttat caagggccca tgaagatata tcctcaagca caaactccac
    15781 gtaaatccag caaacttaag ccgctaatag ctgaagataa agcctataac tatgcgctat
    15841 ctaaggagag aagcaaggtt gagaacatct ttgccaaagt aaaaacgttt aaaatgtttt
    15901 caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg attgctggta
    15961 ttatcaatca tgaactagga ttctagtttt tcaggaagtc taataaagaa actagcaagg
    16021 tcaggcctta ctttattggt ggacatccag gatttaattg tcctctactt gatgatgaag
    16081 tctatgaaga ttattatcta gagtttgaga aagaagagac ttgctctgtt ccacgtcctt
    16141 tcccagaaac aggtatgttg gatttccaag atagaagtcc atggctagag ggacaaaaag
    16201 aaatagatct tagttatgat cttttcagca cagatgcagt gactttggat gaattgcaat
    16261 ctcgaacaat tgcccttcgt tctcttaaac atgataaggg attgaaagtg cattttgcag
    16321 aatttccaaa cctcatcatc tggtcaactt tgaacaaggg acctttcatt acctttgaac
    16381 catggtctgg cttgtcaaca tcccttgaag aaggagatca tttagaagat aagaagaatg
    16441 tttgtctctt agaagccaat caggttgaag aattagggtt tgagatagaa gttttataaa
    16501 aaagcaaaaa ataaataaca aaaacaaaca caaactattg acttcttcaa acaatagtag
    16561 tatattatgt ttgtgaggac taattgactg ttttttaaag atagccaata cactgctgga
    16621 atccagcata gaaaaaataa aaaggagtat acaatatgtc tattgttatc ggtgcagatg
    16681 ctgcaggttt gagattgaaa gaagttgtga aagacttctt agaaaaagaa aacttccacc
    16741 ttgtggatgt tacagctgaa ggtcaagact ttgttgatgt gactctcgct gttgctgcag
    16801 aagtaaacaa agaagaacaa aaccttggta tcgtgattga tgcttatgga gctggtccat
    16861 ttatggttgc aactaagatc aaaggaatgg ttgctgcaga agtatctgac gaacgttcag
    16921 cttatatgac tcgtggccac aacaactcac gtatgatcac tatgggggca caacttgttg
    16981 gtgatgaatt ggctaaaaac atcgctaaag gatttgttaa tggtaaatac gacggtggtc
    17041 gtcaccaaat ccgggttgac atgttgaaca aaatgggcta attagattat agtaagaaag
    17101 gtaagttaaa aatgagaatt gcaattggat gtgaccacat cgtaactgat gaaaaaatgg
    17161 cggtttcaga atttttgaaa tcaaaaggat atgaagtcat tgactttggt acatatgacc
    17221 atacacggac tcactaccca atctttggta aaaaagtagg ggaagcagta actagtggtc
    17281 aagctgatct cggggtatgt atctgtggta ctggtgttgg tatcaacaac gctgtaaata
    17341 aagttccagg tgttcgttct gccttggttc gtgatatgac aacagccctt tatgctaaag
    17401 aacaattgaa cgctaacgtt atcggctttg gtggtaagat tactggtgaa ttgcttatgt
    17461 gtgatatcat cgaagctttc attcatgctg aatacaaacc atctgaagaa aacaagaaat
    17521 tgattgcgaa aattgaacac cttgaaagtc acaatgctca acaaacagac gcaaacttct
    17581 ttacagaatt ccttgaaaaa tgggatcgcg gagaatacca cgactaagag gtgacctatg
    17641 attttaacag tcacaatgaa cccatccatt gatatttcct atcccttgga tgagttgaag
    17701 attgatactg tcaatcgtgt ggtggatgta accaaaacgg ctggtggtaa gggacttaat
    17761 gttacccgag tactttcaga atttggcgat tctgttcttg ctactggttt agtgggtggc
    17821 aaacttggtg agtttttggt tgaacatatc gataatcaag taaagaaaga tttcttctca
    17881 attcagggag aaactcgtaa ctgtatcgct attctccacg gagacaacca aacagaagtt
    17941 cttgaaaaag gtcctgaagt attggaacag gaaggtcaag actttttgga acatttcaaa
    18001 aaactcttgg agtcagttga agtagtggcc atctcaggta gtctgccagc tggccttcca
    18061 gttgattact atgcgagctt ggtagaactt gctaatcaag ctggcaagcc tgtagtcttg
    18121 gactgctcag gtgcagcact tcaggctgtt cttgaatcac cccataaacc aacagtcatc
    18181 aaaccaaata atgaagaatt gtctcagctt cttggaagag aagtttctga ggatttggat
    18241 gaattaaaag aagtacttca agaacctttg tttgcaggga ttgaatggat tatcgtttca
    18301 cttggtgcca acggtacttt tgccaaacat ggtgacactt tctacaaggt agatattcct
    18361 agaattcagg tggtaaatcc tgttggatct ggagactcta ctgtggcagg aatttcttca
    18421 ggacttcttc acaaagaatc ggatgcagaa ttactcatca aggcaaatgt ccttggtatg
    18481 ctcaatgctc aagaaaaaat gactggtcat gtcaacatgg ccaactatca agctctatat
    18541 gatcaattaa tagtaaaaga ggtataaaat ggctttaaca gaacaaaaac gtgtacgctt
    18601 agaaaaactt tctgatgaaa atggtatcat ctcagctctt gcatttgacc aacgtggtgc
    18661 tttgaaacgc ctcatggctc aacaccaaac agaagaacca actgtggccc aaatggaaga
    18721 acttaaagtc ttggtagcag atgaattgac taaatacgct tcatctatgc ttcttgaccc
    18781 tgagtatgga cttccagcaa ctaaagctct tgatgaaaaa gctggtcttc tccttgctta
    18841 tgaaaaaaca ggttatgaca caacaagcac aaaacgcttg ccagactgct tggatgtttg
    18901 gtctgcaaaa cgtattaaag aagaaggtgc agatgcagtt aaattcttgc tttactatga
    18961 tgtagatagc tcagacgaac tcaatcaaga aaaacaagcc tacatcgaac gcatcggttc
    19021 tgagtgtgtg gctgaagata tcccattctt ccttgaaatc cttgcttacg atgaaaaaat
    19081 tgcggatgca ggttctgtag aatacgctaa agtaaaacca cacaaagtta tcggcgctat
    19141 gaaagtcttt tcagacccac gctttaacat tgatgttttg aaagttgaag ttcctgttaa
    19201 cattaaatat gttgaaggct tcgctgaagg tgaagtagtt tatacacgtg aagaagcagc
    19261 agccttcttc aaagcgcaag atgaagcaac gaacttgcca tacatctact tgagtgctgg
    19321 tgtatcagct aaactcttcc aagatactct tgtatttgct catgaatcag gtgcaaactt
    19381 taacggagtt ctttgtggcc gtgctacatg ggcaggatca gttgaagctt acatcaaaga
    19441 tggtgaagca gcagctcgcg aatggcttcg cacaactgga tttgaaaaca ttgacgaact
    19501 caacaaagtt cttcaaagaa cagcaacttc atggaaagaa cgcgtgtaag aaagtcctcc
    19561 tagtttagga acatgaatct aaaaaaattt aaaaaaagtt gtatgtaaag gtttacaaaa
    19621 taacttactt gtgctatact taaatcacaa gttaatatga attagaaagt aactatatga
    19681 agtataataa aaataggata tagtttattt tacgagctag gaaggaaaaa tacggaaaca
    19741 atattgccag aataaactat atttagatgc acatttcatt cattgtttta taaaaggaga
    19801 agataaacgg ctactaaaaa gagttttaaa gcgttagttg taggactagg tattgtttca
    19861 atattctcat cagccttacc tatggttagt ggttctgtat ttgcagatag tgccctaact
    19921 acagtataca gtagataaag caaatgatat tgttttgaat gttgatggga ataaatttta
    19981 taatgtttcg gtttcagaag atattgtaaa tgctggtcaa attttggaag attattttta
    20041 tgtagataaa tttggaaata taaatttaaa aggcactcct gaagagttag caaaaaatat
    20101 tggtatttct gtacaagaag caagtttgat gtatgaagct gtaaaagagt tacccaacgt
    20161 ttacgaaaga ggtcctgtag gttttcgttt caatcttggt cctcaagtga gggggatggg
    20221 tggctgggct gctggagctt tcgctactgg atatgctgga tggcatttga aacaatttgc
    20281 ggttaatcct gttacatctg gatttgttgc tgtaataagt ggtgcgattg gctgggctgt
    20341 aaaaactgct gtagaaaatt attggacagt tgctgtagct acagtagaag tgccgtttgt
    20401 gaaccttgtt tacaccatag atttacctta gaggttattt ctttatgaat cattct
//
LOCUS       DAVIME010000035        20412 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVIME010000035 DAVIME010000000
VERSION     DAVIME010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20412
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.035"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            117..3218
                     /locus_tag="VV588_001443"
     CDS             117..3218
                     /locus_tag="VV588_001443"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU7083771.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRVSFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3301..4308
                     /gene="pfkA"
                     /locus_tag="VV588_001444"
     CDS             3301..4308
                     /gene="pfkA"
                     /locus_tag="VV588_001444"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU7083772.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSADEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4367..5872
                     /gene="pyk"
                     /locus_tag="VV588_001445"
     CDS             4367..5872
                     /gene="pyk"
                     /locus_tag="VV588_001445"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU7083773.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6146..6394)
                     /locus_tag="VV588_001446"
     CDS             complement(6146..6394)
                     /locus_tag="VV588_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU7083774.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(6560..6785)
                     /locus_tag="VV588_001447"
                     /pseudo
     CDS             complement(6560..6785)
                     /locus_tag="VV588_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7633..8505
                     /locus_tag="VV588_001448"
     CDS             7633..8505
                     /locus_tag="VV588_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU7083775.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDTFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTESTTDVKVHAEKMEAFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8651..8995)
                     /locus_tag="VV588_001449"
                     /pseudo
     CDS             complement(8651..8995)
                     /locus_tag="VV588_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9138..9449
                     /locus_tag="VV588_001450"
     CDS             9138..9449
                     /locus_tag="VV588_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083776.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            9453..10169
                     /locus_tag="VV588_001451"
     CDS             9453..10169
                     /locus_tag="VV588_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU7083777.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10298..11113)
                     /locus_tag="VV588_001452"
     CDS             complement(10298..11113)
                     /locus_tag="VV588_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU7083778.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11110..12015)
                     /locus_tag="VV588_001453"
     CDS             complement(11110..12015)
                     /locus_tag="VV588_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU7083779.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            12472..14601
                     /locus_tag="VV588_001454"
     CDS             12472..14601
                     /locus_tag="VV588_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU7083780.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            14588..15037
                     /locus_tag="VV588_001455"
     CDS             14588..15037
                     /locus_tag="VV588_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU7083781.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            15095..15367
                     /locus_tag="VV588_001456"
     CDS             15095..15367
                     /locus_tag="VV588_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU7083782.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15721..15912)
                     /locus_tag="VV588_001457"
     CDS             complement(15721..15912)
                     /locus_tag="VV588_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083783.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16340..17098
                     /locus_tag="VV588_001458"
     CDS             16340..17098
                     /locus_tag="VV588_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083784.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17100..19088
                     /locus_tag="VV588_001459"
     CDS             17100..19088
                     /locus_tag="VV588_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083785.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFLAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19130..19774)
                     /locus_tag="VV588_001460"
     CDS             complement(19130..19774)
                     /locus_tag="VV588_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU7083786.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(19800..>20412)
                     /locus_tag="VV588_001461"
     CDS             complement(19800..>20412)
                     /locus_tag="VV588_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU7083787.1"
                     /translation="GKLGLSKQDLLYPRKGKALKKQASTNFKPAGQSIEQRSEAINLR
                     LENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVNQALKLILKQHKI
                     LSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRRWLPKGIKKMTPK
                     EVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
BASE COUNT         6236 a         3724 c         4315 g         6137 t
ORIGIN      
        1 caaaaataca aatgaataga aaataaatta gtaagctgat gaaatttttc tcaagagaag
       61 ccatttatag gtgaaaatgg tataatatag tgagaaggat agaggagaag tgtaaattga
      121 tcgcacaact agatacaaaa acagtctata gttttatgga aagcgtcatt tcgatcgaaa
      181 agtatgtgag agcagctaaa gaatacggct acactcattt ggctatgatg gatattgaca
      241 atctttatgg cgctttcgac tttctagaga ttacaaaaaa atacggcatt catcctttgc
      301 tagggcttga aatgacagtg tttgtagatg atcaggaagt gaatttgcgc tttttagctc
      361 tatctagtgt gggctatcag cagttgatga agctttcgac agccaagatg cagggggaga
      421 aaacttggtc agtcctgtcc cagtacctgg aggatatcgc ggtcattgtg tcttattttg
      481 atagagttga gtcgttagaa ctaggctgtg attactatat aggggtttat ccagaaacac
      541 tagcaagcga atttcatcat cctatcttac ctctttatcg ggtcaacgct tttgaaagca
      601 gggatagaga agttcttcaa gttttaacag cgattaaaga aaatctaccg ctcagagaag
      661 ttcccttgcg ttcgagacaa gatgtcttta tatcagcaag ttctttagag aaactattcc
      721 aagagcgttt tccgcaagct ttggacaatt tagaaaagct tatttcaggc atttcttacg
      781 acttggatac tagtctgaaa ctgcctcgtt ttaatccagc tagaccagca gtagaggagt
      841 tgagagagcg tgctgaactg gggcttgttc agaaggggtt gactagtaaa gaatatcaag
      901 atagactaga ccaagaattg tctgttattc atgatatggg ctttgatgat tatttcttgg
      961 ttgtttggga tttgttgcgt tttggacgat cgaatggcta ttatatggga atgggaaggg
     1021 gttctgcagt aggcagtttg gtttcttatg ccttagacat cacggggatt gacccagtag
     1081 agaaaaatct gatttttgaa cgctttctta atcgtgaacg ctataccatg cctgatattg
     1141 atattgatat cccagatatt tatcgtccag attttatcag atatgttggt aataaatatg
     1201 gtagtaaaca tgcggcacaa atcgttactt tttcaacctt tggagccaag caagctcttc
     1261 gagatgtctt gaaacgcttt ggtgtgccag agtatgaatt atctgcaatt actaagaaaa
     1321 tcagttttcg tgacaatctt aagtcggcct atgagggcaa tctccagttt cgtcagcaaa
     1381 tcaatagtaa gttagaatac caaaaagctt ttgagattgc ttgcaagata gagggctatc
     1441 caagacaaac ctctgtccat gcggctggtg ttgtaattag tgaccaagat ttaaccaact
     1501 atattcctct aaagtatggt gatgaaattc cactgactca gtatgatgct catggagttg
     1561 aggctagcgg acttttgaag atggactttc tgggactacg aaatttgacc tttgtccaga
     1621 agatgcaaga gttgcttgct gaaatagaag gtattcacct taaaattgaa gaaatagatt
     1681 tggaagacaa agaaacgtta gatttatttg cctctggaaa tacaaaaggt atctttcaat
     1741 ttgagcaacc aggtgccatt cgtctgctta agcgtgtgca accagtctgt tttgaagatg
     1801 tcgtcgcgac tacttctcta aatcgaccgg gtgctagtga ctatatcaat aattttgtgg
     1861 caagaaagca tgggcaggaa gaagtgactg ttctggatcc agtactggag gatattttgg
     1921 ctccaaccta cggcataatg ctctatcagg agcaggttat gcaggttgcc cagcgatttg
     1981 ccggatttag tcttgggaaa gccgatattt tgcgtcgggc tatggggaaa aaggatgcct
     2041 ctgccatgca tgagatgagg gtttccttta ttcaaggttc attagaagct ggtcatactg
     2101 tggaaaaagc agagcaggtc tttgatgtta tggagaagtt tgcaggttat ggttttaaca
     2161 ggtcacacgc ctatgcctac tcagccttgg ccttccagtt ggcttatttt aaaacacatt
     2221 atccagccat tttttatcag gtcatgttaa attcttccaa cagtgattac ttaatagatg
     2281 cacttgaagc aggttttgaa gtagcctctc tatccatcaa caccattccc tatcacgata
     2341 aaattgccaa caaggccatc tatctaggtt tgaaatccat taaaggagtc agtaatgatt
     2401 tagctctctg gattattgaa aatagacctt attctaacat tgaagatttt atagctaaat
     2461 tacctgagaa ttatctgaaa cttcctctgc tagaaccttt ggtaaaagtt ggtcttttcg
     2521 attcatttga aaaaaatcgt caaaaagtat ttaataattt agctaatcta tttgaatttg
     2581 tgaaagagtt gggaagtttg tttggagatg ctatttatag ttggcaggaa tcggaagatt
     2641 ggacggaaca agaaaaattt tatatggaac aagagctttt agggataggt gtcagcaaac
     2701 atccactaca agctattgca agtaaggcta tttacccgat taccccaatc ggaaatttgt
     2761 cagaaaatag ctatgctatt atcttggttg aagttcagaa aataaaagtg attcgtacca
     2821 aaaagggtga aaatatggcc ttcttacagg cagatgatag taagaaaaaa ttggatgtca
     2881 ctctcttttc agacttatat cgtcaggttg gacaggaaat aaaagaggga gccttctact
     2941 atgtaaaagg aaaaatacaa tcacgtgatg gccgtctgca aatgattgca caagaaataa
     3001 gagaagcagt tgctgaacgc ttttggatac aggtgaaaaa tcatgaatcg gatcaagaaa
     3061 tttcacgcat tttagaacaa tttaaaggcc caatcccagt catcatccgg tatgaagagg
     3121 aacagaaaac catcgtttct ccccatcatt ttgtagctaa atccaatgaa ttagaggaga
     3181 aattgaatga aatcgttatg aaaacgattt atcgctaaaa atacggaaaa tagaagaatt
     3241 ttaaaatcaa atgtgatata atcaagaaga atgttaaaag aaaaaggagc ataaaccaat
     3301 atgaaacgta ttgctgtttt gactagtggc ggagacgcac ctggtatgaa cgctgccatc
     3361 cgtgcagttg ttcgtcaagc aatttcagaa ggaatggaag tgtttggtat ctatgacgga
     3421 tatgctggta tggttgccgg tgaaattcat cccctagatg cagcttcagt aggggacatc
     3481 atttctcgtg gtggtacttt tcttcactca gctcgttacc cagagttcgc tcaacttgaa
     3541 gggcaactta aagggattga gcaattgaaa aaacacggaa ttgaaggtgt agttgttatc
     3601 ggtggtgacg gatcttacca cggcgctatg cgtttgactg aacatggctt cccagctatt
     3661 ggtcttccag gtacaatcga taacgatatc gttggtactg actttacaat cggttttgac
     3721 acagcggtta ctactgccat ggacgctatc gataagattc gtgatacatc atcaagtcac
     3781 cgtcgtactt ttgtaatcga agttatggga cgtaacgctg gtgatatcgc tctttgggct
     3841 ggtattgcaa ctggtgctga tgaaatcatc atccctgaag caggcttcaa gatggaagat
     3901 atcgtagcaa gcatcaaagc tggttatgaa tgtggtaaaa aacacaatat catcgtctta
     3961 gctgaaggtg tgatgtcagc ggatgaattt ggtcaaaaac ttaaagaagc tggagataca
     4021 agcgaccttc gtgtaacaga acttggacat attcaacgtg gtggttctcc aactgcgcgt
     4081 gaccgtgttt tggcgtcacg tatgggtgca catgctgtta aacttcttaa agaaggtatc
     4141 ggtggtgttg cggttggtat tcgtaacgaa aaaatggttg aaaatccaat tcttggtact
     4201 gcagaagaag gggcattgtt tagccttact gcagaaggta agattgtggt taacaaccca
     4261 cacaaagccg atattgagct atctagcttg aataagagct tgtcataatt tacaatttag
     4321 ttaataagac caaaaaggtc atatatataa aggagtcaca aaaatcatga acaaacgtgt
     4381 aaaaatcgtt gcaactttgg gtcctgcggt agaaatccgt ggtggtaaaa aattcggtga
     4441 ggacggatac tggggtgaaa aacttgatgt tgaagcttca gctaaaaaca ttgctaaatt
     4501 gattgaagct ggtgctaaca cattccgatt caacttctca cacggcgacc accaagaaca
     4561 aggtgagcgt atggcaactg ttaaacttgc ggaaaaaatt gcaggtaaaa aagttggttt
     4621 ccttcttgat acaaaaggac ctgaaatccg tacagaattg ttcgaaggtg aagctaaaga
     4681 atattcatac aaaactggtg aaaaaattcg tgttgcaact aaacaaggaa tcaaatcaac
     4741 tcgtgaagtg attgcgttga acgttgctgg tgctcttgat atctatgatg atgttgaagt
     4801 tggtcgtcaa gttttggttg acgatggtaa acttggtctt cgtgtggttg ctaaagatga
     4861 tgcaactcgt gaatttgaag ttgaagttga aaacgatggt atcatcgcta aacaaaaagg
     4921 tgtgaacatc cctaacacta aaattccttt cccagctctt gctgaacgcg ataacgacga
     4981 tatccgtttc ggtcttgaac aaggtatcaa cttcatcgca atttcattcg tacgtactgc
     5041 aaaagatgtg aacgaagttc gtgcaatctg tgaagaaact ggaaacggac atgttcaatt
     5101 gttcgctaaa atcgaaaacc aacaaggtat cgataactta gacgaaatca tcgaagcagc
     5161 tgatggtatt atgattgctc gtggtgatat gggtatcgaa gtaccgttcg aaatggttcc
     5221 agtttatcaa aaaatgatta tcaagaaagt caatgctgca ggtaaagttg ttatcactgc
     5281 aacaaacatg cttgaaacaa tgactgaaaa accacgtgca actcgttcag aagtatcaga
     5341 cgtattcaac gctgttatcg acggaactga cgctacaatg ctgtcaggcg agtctgcaaa
     5401 cggtaaatac ccactcgagt cagtaactac aatggctaca atcgacaaga acgctcaagc
     5461 tcttcttaat gaatacggac gtcttgattc agattcattt gagcgtaact ctaagacaga
     5521 agtaatggct tctgctgtta aagatgctac taactcaatg gatatcaaat tggttgtaac
     5581 tcttactaag acaggtcata ctgcacgttt gatttctaaa taccgtccaa atgctgacat
     5641 cttagcattg acatttgacg aattgacaga acgtggcttg atgttgaact ggggtgttat
     5701 cccaatgttg acagatgctc catcttcaac tgacgatatg ttcgaaatcg ctgaacgtaa
     5761 agcggtagaa gcaggtctcg ttgagtcagg cgatgatatc gttatcgttg ctggtgtgcc
     5821 agtaggagaa gctgttcgca caaacacaat gcgtatccgc acagtacgtt aagaaaaata
     5881 taaaaaccta tcatatccag ctttatagcc tgtatgatgg gctctttttt tgtccagggg
     5941 gcaaaaaggg ggcaaaactt tcataatgga ttgatactct tcgaaaatct cttcaaacca
     6001 cgtcagcgtc gccttaccgt actcaagtac agcttgcggc tagcttccta gtttgctctt
     6061 tgattttcat tgagtatgaa ataagatatg cacaaattga ttagaaagtc aaatgaattt
     6121 ctacaaatgt tttagcaatc gcaatctact tgtctagatt cgatctgata tattttcgat
     6181 ttaatgatat ggtatttaaa acctccaaag tagcttgctc cattctttta cttacgtgag
     6241 tgtagatgtt atttactgtt ttagcgtttt tgtgttccac tctaaccatt atagcattct
     6301 tctcagctag tgtactaagg agtgtgtgcc tgaaaatatg ggaactaagg ggctggttta
     6361 tcggtttctc tagtttagta tttgcctttt gcaaagtgat cttaaatgcc tttctctaaa
     6421 tttacatatc actattgttt aacaaaatct aatctacttt aggtcactta ttcttttttg
     6481 caatgtagaa tgaacttttt caaagttttt cgaatctttt aaaatctgtt tgttttatat
     6541 cgccattctc cccccttttt taattctccc tatatagcct gacaactttc ccgatggtac
     6601 aaatatggtt gctttcgtct aggtggatgt cggggtattc gggattgagt ttttttgagg
     6661 tagccttggc ggagtttctt gacatagtta gcgccgtcta cttggaagat gccgatggta
     6721 ttatagtcaa tctgtggggt attcttgata aataggtagt cgctgtttct tatctttggc
     6781 tccatggact tgctgacgac ataagcgatt gggtcgtagt cgtctgggat aatggaaact
     6841 ccatatctaa atcgttgtcc tgcatcgagc ggctacctgc agagataaac tacctaacaa
     6901 gagagtaagt agtctgtctg tagtcgtcca gtctgatgat ttttacgata cttcgttttt
     6961 ctgatcatac agttgcctct cggcataggt cagaacttta ccttgtctgg gtggtgcccg
     7021 ttggtcgtag atagattgga tatcgctagg agaatccttt tgaactggag gaaagagggc
     7081 atcaatcaag ctactgaata ctttaactaa gtcaaatata gtatttttct tagtagacct
     7141 aacccttttt tcataatttc taatggtgtt tttacttata cctatcttag tacccaattc
     7201 ttattgagtc caaccattac tagtctatat tgttttatag ttgattgagt ttggaatagt
     7261 acgctgtagc tgctaaaaca tttctaggaa ttaatttgcc tttcctaata gagttgttca
     7321 tatcttattt caatctatga tgtttttcac ctctaacaat cgcaatctct tctttatcca
     7381 tgaatgaaaa cgttttctat ttttgtaagt aaagcatcac acgaaattca cgaaaatgaa
     7441 aacctttgtt gtgttttcgt aaaaaatttg ttgacagagc acgaaacgcc tactataatt
     7501 aagtcaagct taaggaaata acaaaaaaac aaatcggagg gaaagacgat gaacacatta
     7561 aatgagaaag taatcaatat ctgtaaagca gtagttaaag aaactttaat ccaagacatt
     7621 taggagaaag aaatgaagaa atcaagaaaa ttagccacat taggaatctg ttcagccttg
     7681 tttttaggct tggctgcttg tcaacaacaa catgctactt ctgaggggac gaatcaaagg
     7741 caaagcagtt cagcgaaagt tccatggaaa gcttcataca ccaacctaaa caaccaggta
     7801 agtacagaag aggtcaaatc tctcttatca gctcacttgg atccaaatag tgttgataca
     7861 ttttttaatc tcgttaatga ctataatacc attgtcggct caactggctt atcaggagat
     7921 ttcacttcct ttactcacac cgaatacgat gttgagaaaa tcagtcatct ctggaatcaa
     7981 aagaagggcg attttgttgg gaccaactgc cgtatcaata gttattgtct tttgaaaaat
     8041 tcagtcacca ttccaaagct tgaaaagaat gaccagttgc ttttcctaga taatgatgcg
     8101 attgataaag gaaaggtctt tgattcacaa gataaggaag agtttgatat tctattttcg
     8161 agagttccaa ctgagtcaac tacagatgtc aaggttcacg ctgaaaagat ggaagcattc
     8221 ttctcacaat ttcaattcaa tgaaaaagct cgaatgctgt ctgtagtctt gcacgacaat
     8281 ttggatggcg agtatctgtt tgtaggccac gttggggtct tagtacctgc tgatgacggt
     8341 ttcttatttg tagagaaatt gactttcgaa gagccctacc aagcgattaa atttgctagt
     8401 aaggaagatt gctacaagta tttgggcacc aagtatgcgg attatacagg cgagggactg
     8461 gctaagcctt ttatcatgga taatgataag tgggttaaac tttaatagtg ttatgatatg
     8521 acagtaatct taggattttt atttctattt ttgataagtt ggtgggttat ttcaatcgtt
     8581 aatagccaga aaccacgcaa aaatgaaaca tttattggct atgtccaaag atacgatatt
     8641 gatgggaatg gctatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaatcg
     8701 taacaccact ttgaacaaga gttacttaaa cccattggct ccgacggatt aagttgcttt
     8761 cgtgaatacc aaaatcagcc gcaatttctt cataagtgcg gtattctcgc acatattgaa
     8821 gagtggccat aagaaggtct tctaggctta atttaggttt tcgtccacct tttgcgtgtt
     8881 taagttgata agctgttttt aatacagcta atatctcttc aaaagtcgtg cgctgaacac
     8941 caacaagacg tttaaatcgt gcatcagtta gttgtttact tgcttcataa ttcatagaac
     9001 tactatacca tattttgttt cgcaggaagt ctaatgctaa aatcttatca gtgagaagat
     9061 ttcttaaagt ttattctttg tagtttcatc tgtattagta cataatttaa cttagagaaa
     9121 ataggaggac taatcgaatg gaattaaaag attttacaga aaaagaacag gaaatgatta
     9181 agaaaaggct tacaatgtct aatattagtg acaaagaaac tactgagaag attctggcgc
     9241 tagtcccaca agacttgatt aagcgaatcc cgttttttgt cagaaaacat gctacaacac
     9301 gtacgattaa acgcatttca attgaatacc ctgaactcta cgctgtagct caaacaagtg
     9361 gtgagattcc agaaaaaaaa cgcgaagaat tgcgtcagat tatcacaact atctttgaac
     9421 aaaagatgaa taagcatagt attaagtaga gaatgaaaaa atattttatt ggcggtttgg
     9481 gaagcaatgc ctatcatagc aaggattttc ttcaagaact agattcgcag gtctattttc
     9541 taaatccata tgaaaagcat cttcgagatg aaacagaatt gaaatcatgg tttaaaaatg
     9601 aaattgtaga ggaagaatct atctgtctga taggccattc tcttggagga gatttagctc
     9661 gttatttcgc atcggaattt gaagaagtaa agaaactgat tcttttggat ggtggctatc
     9721 tagatttaga taagatttta cctttggata cagagttaga ggaaactaaa aattatatca
     9781 aatctcaaat tgtttcggac ttagatgttc ttacttctaa agaaaaatct gaagcaaagc
     9841 attggtcaga aaatatggag aaagctgtaa gacagtctta tcactggaat gttgagtata
     9901 atagatatga gttggctata aattatgaaa atatagaagc gatactccgc ctacggagaa
     9961 aaatacaagc ttttaagaga gaagtgggag ataccttgtt tattagtcct cgctatccta
    10021 atgaagctac atggagagag gaagccctaa aagaattgcc agactatttt gatactattt
    10081 ttttagaaaa ctttggccat gagctttata ctcaagcacc taaagaaatc gctagtctaa
    10141 tgaatgagtg gctcgcttat tttctatgag ctacttgtat tgctgggaat ggtataagat
    10201 gaaaatctac aagtcactaa ttttcatata acaaaaaacg aacaggctct ttttctgtta
    10261 ttcagaagag aacttgttcg tttttatctt gattttctta aaaagctcta tatacatagg
    10321 gattttctgg tttatcgact ttggtaaagc tgtcgatttc caaggttgga aggttttgtt
    10381 tgagttcttt atggtagtga ttgaccagtt ttcctttggc tgttatccaa gtgttgtttt
    10441 catactgccg ggtattgccc ttggtcagca atccatagac accagaatct gcgatacagt
    10501 ggataatgcc gaatcggaac agaaattgac tattggcatg actggggtcg ttatagacaa
    10561 agcctgtaaa ctggattgtc ttgccctcaa actcatctgg atagtcgtag atagcctcca
    10621 tgacttccat atagttttca ttagtgatct gaatactatc ttgggataag tatttatccg
    10681 ccgccgttcg catttccttt tcataggctg attttgaaaa ataagaactg gtatctggtt
    10741 tcaaatattg gcttgtcgtc ccttcgcttg tctgaatggc tagatccgtt ccttccgata
    10801 gggggaaatg ataaccttta gcagaaacag tctgagaatc caagctaaca gttgggaaag
    10861 ttaagccgat gacaagtgga atagccagaa gagaaatact cgtcatcttg gctaatcggc
    10921 tgttcagatg actgtgggtt ttgacttgct tcatccagat atacaattga acgatagcca
    10981 agataaaaga aagcaccatg gagatatagg ccagatagga atagtgcatg ttgatgtact
    11041 ggtttagttt gcccgacaga tggaggtaaa tagtcagttc aaaatagcca gctaaaacta
    11101 aaaatcgaat cataggatga ctccaatcaa gagagaatag actaagacga caagagttac
    11161 aattgttatg aagtgactga taaatcgtgc tttcaagtaa tttttcatca tgagaatatt
    11221 tttgatatcc agcattggac caatgacgag aaaggccaga actggtgcca aaccgaaact
    11281 cgagagaaga gaagcaccta taaaggcatc cgcctcacta cagagcgaaa gaagaaaggc
    11341 taaaatcatc aagagcagga tggcaaaaag aggggtcgca ctgatagagg tcagaatccg
    11401 agtcggaacg tagacctgta ttatagaagc aaagaggcag ccaaatacca aataacgccc
    11461 cgtatcaaaa aattcatcaa tggcctgcac aaagacttga aaaacttttt ttgcagaact
    11521 caagtaagaa aaatcatgct catgacaagc cagacgattt tctttctgaa tcggttcttg
    11581 ccagaaaaat cctagaaaaa ttcctagtat tacagccaca agaatggaac ccagagctcg
    11641 taatagggcg acatggaagg agttgccaaa ggcagaatag gtcgcaaaaa gaacaatggg
    11701 attgataaca ggtgctgtca caagaaaagg aacggccgtg taacttggaa cctttttttc
    11761 cagaaaacga ttgatgatgg ggacgattcc acattcacaa gaagggaaaa acataccgac
    11821 gaaggtccca aaaaagattc tcccccaacg atttcgaggg agaaaatgat aaaccttgtc
    11881 aggtgtgata taaacttcaa tcagccctga gacaatgctt cctatcagaa cgaagggaag
    11941 ggcttcaatg ataatggaga gaaaaatggc tccagtttga agtacactag atgggagttg
    12001 ttgaaaagca gtcatctagt ttttcttttc tgctttggct tttttctctt tgtcatcagg
    12061 gaaagtaact tgtttcaaat cagggagttt agcaaactct tcaaacatct tgtccaagtc
    12121 gtctcgtttt gtaaatttta cagccatagg tgtacctcga ttctaaattc tacctctatt
    12181 atactattat tttgcggaaa agggagtttt ttaatttgtt ttcgatagtt gatactcttc
    12241 gaaaatctct tcaaaccacg tcagcttcgc cttaccgtag tacggttact gacttcgtca
    12301 gttctatcca caacctcaaa acagtgtttt gagctgactt cgtcagtctt atccacaacc
    12361 tcaaaacagt attttgagca gcctacggct agcttcctag tttgcttttt gatttttatt
    12421 gagtatgaaa aggattggag aaagccttcc agcttgtggt ataatagatt tatggataaa
    12481 aaatatgaaa aaatctctca ggatttggga gtgacgttaa agcaaattga taccgttcta
    12541 agtttgacag ctgaaggggc gactattccc tttatcgcgc gttatcgcaa ggacatgact
    12601 ggtagtctgg atgaggtggc gattaaggct attattgatt tggataaaag tctgacaaat
    12661 ctcaatgacc gtaaggaagc tgtcttagct aagattcaag aacaaggtaa gttgaccaag
    12721 gaattggaag aagctatctt agttgccgaa aaattagcag acgttgaaga actctatctt
    12781 ccttataagg aaaagcgtcg taccaaggca accattgccc gtgaagctgg actctttcct
    12841 cttgctcgct tgattttgca gaatatagtt gacttagaga aagaagctga aaagttcgtc
    12901 tgtgaaggat ttgcgactgg caaggaagcc ttgaccggtg cagttgatat tttggtcgaa
    12961 gccttatcgg aagatgtgac cttgcgttct atgacttatc aggaagtgct gagacactct
    13021 aaactcactt ctcaagccaa ggatgaaagt cttgatgaaa agcaggtttt tcagatttat
    13081 tatgattttt cagagacagt tggaactatg caaggctatc gtaccttggc tctcaatcgt
    13141 ggggagaaac ttggtgtctt gaagatcggt tttgaacatg cgacggaccg tattcttgcc
    13201 ttctttgcta ctcgtttcaa ggtgaaaaat gcttatattg atgaagttgt tcagcaatcc
    13261 gttaagaaaa aggtcttgcc tgctattgag cgtcgtattc ggacagaatt aactgagaaa
    13321 gctgaagagg gagctatcca acttttttct gacaatctgc gcaatctcct cttggttgct
    13381 ccactgaaag ggcgcgtggt tcttgggttt gacccagcct ttcgtacagg tgccaagcta
    13441 gctgtcgtgg atgcaacagg aaaaatgctg acaactcagg ttatttatcc tgttaaacca
    13501 gcatcagctc gtcaaatcga agaagccaag aaagatttag cagatttaat tggtcaatac
    13561 ggtgtagaga ttattgccat tggaaatgga acggccagtc gtgaaagtga agcttttgta
    13621 gcggaagttc tgaaagattt ccctgaagtc agctatgtta tcgttaatga aagtggtgct
    13681 tctgtctatt ctgccagcga acttgctcgt caggagtttc cagacttgac cgttgaaaaa
    13741 cgctctgcca tttctatcgc ccgtcgtttg caagatcctc ttgcggaatt ggtcaaaatc
    13801 gatcctaagt caattggtgt cggtcaatac caacacgatg tcagtcagaa gaaactatct
    13861 gagagtctgg actttgttgt cgatacagtg gttaaccaag ttggtgtcaa tgtcaataca
    13921 gctagcccag ctcttctttc acacgtagct ggactcaata aaaccatttc tgaaaatatc
    13981 gtcaaatacc gtgaggaaga gggaaaaatc acttcacgct cccaaatcaa gaaagttcct
    14041 cgtttggggg ccaaggcttt tgaacaggct gctggtttcc tccgtatccc tgaaagtagc
    14101 aatatccttg ataatacagg agttcaccca gaaaattacg ctgccgttaa ggaactcttc
    14161 aaatgcttgg acattaagga tctgaatgaa gaggcccaaa gtaaactcaa gtcgctttca
    14221 gtcaaggaaa tggcgcaaga gttagacctt ggtccagaaa ctcttaaaga tatcattgca
    14281 gatcttctca aaccaggtcg agatttccgt gattcctttg atgctccagt tctccgtcaa
    14341 gatgtcctag atatcaagga cttagtggtt ggacaaaagc tagaaggagt ggtgcgtaat
    14401 gttgttgatt tcggtgcttt tgttgatatc ggaattcatg aggacggtct catccatatt
    14461 tcccatatga gtcgcaagtt tatcaaacac cctagtcaag tggtggcagt tggagatttg
    14521 gtgagcgttt gggttaagaa aattgatact gaacgtgaaa aagttaatct gtctctccta
    14581 gctccaaatg aaactgactg attacgtcaa gcaggtttca ctagaagact tcggcagacc
    14641 ttttatccat catgtccagt ggaataggcg tctacgttcg acaggtgggc gatttttccc
    14701 caaagatggg catttggatt ttaatcccaa ggtttatcag gaactggggt tggacgtttt
    14761 taggaaaatt gtccgacatg aactctgtca ttatcacctc tattttcaag ggaaaggcta
    14821 tcaacacaag gatcgggatt ttaaggaact gttgaaagca gtggatggat tacggtttgt
    14881 accatccttg cccaatagta actccaagcc aatcaagctc tatcgttgcc aatcctgcca
    14941 gcaaacttat cagcgtaagc gtaggattga tacccaacgc tatcgctgtg gactttgtcg
    15001 aggaaagttg ctattagtaa atcagcctga ggactgatga aagccgagcc tatccgtgat
    15061 atactagtct aacctagcag aaagaggaaa tatcatgaac agtaagtttt ataaaatgag
    15121 acgaaatcgc atgatttcag gagttttagc aggtctgtca gacaagtgga actttgatgt
    15181 tacccttgta cgttttctgt ttgccatttt tacagtcgca aactttggac ttggggtgat
    15241 tatctatatc atcctagctt ctatcatgcc aaccaaggaa gaaatcgaag cagaaatgta
    15301 cggaacaggc ccacgtaaac gcaaagaagc tcaagccatt gacgataatg aaggctggtt
    15361 ttggtgaggt tttacaaaag atttggaata cgcaaaaagc tttaaatcaa tagtctaaac
    15421 tgcttgattt aaagcttttt tacttttata ctcaataaaa atcaaagtgc aaactaggaa
    15481 gccagccgca ggctgtaatt tagtcggcaa tgtgaagttg atatagtttg cactttgatt
    15541 tttgaatagt attaataata tttcgccagc ttcatccaca aactatagtg gattggaact
    15601 agaataggac acctatactt ctaaaaaatt gttagaaatc gatttgactg tcctgatcga
    15661 tttgtcctgt tcttatttca ttttactata aaagcagtaa tttaaacgca gttttttaat
    15721 ctatttttgc tgttgagaca atacattttt ggaaaaatgg tggatgctga taacaactga
    15781 taaccagcaa ataacataag cagtgccggt aaattctgta ccgataaagt gtgtgtgttc
    15841 aactaagagc tgaccgatga atggagagag cagatagaga agtccgatga gtatatgttc
    15901 tttgtgtttc attaaagcgc accttctttc cttataggtt gaacgacttg caagtgttaa
    15961 attgaatggt atgttatcta ggtaacctta ctaaaatgtt agttcccgct tcctcctttt
    16021 caaagtaagc cttttcacac ttatatttta caactttaaa aataggaaat caaatcattt
    16081 tctaagtaat tttgcttata tttcacccaa tcttacaaaa atgtaagatt aaagtctctt
    16141 ttgtaaggtt aggttatggc aagcggtctt tttttgatgt aaactagact cataaagaac
    16201 aaaggagtaa catcatgaaa caaatcttac ataagaaaac tagaaaacca agtcacaaag
    16261 aaattgagcg cgttcagctg ggatgcacta tgatgcaagc tacatttcat ttgatgggat
    16321 attaagaaag gagattctca tgacactttt agatgtaaaa cacgttcaaa aaatttataa
    16381 aacacgtttt cagggcaacc aagtagaagc cctcaaggat attcacttta ccgtcgaaaa
    16441 gggtgactac gttgccatca tgggtgagtc tggttctggt aaatcaactc ttctcaatat
    16501 tctagctatg ctggataaac caagtcgtgg tcaggtttac ttgaatggaa ctgacaccgc
    16561 aaccattaaa aattcacagg cctctagctt ccgtcgtgaa aagttgggct ttgtcttcca
    16621 agactttaac ttgctagata ctctatctgt aaaggacaat atcttgcttc cgcttgtctt
    16681 gtcaagaaga cctattacag agatgatgaa gaaattggtg gtgacagctg agaatctggg
    16741 aataaaccaa ttacaagaga agtaccctta cgagatttct ggtggtcaga aacagcgtgt
    16801 agcagtagcc cgcgccatca tcacagaacc tgaaattctc cttgcggacg aaccgacagg
    16861 agctcttgac tccaagtcat ctgcagcctt acttgatgtc tttgatgaaa tcaatgagcg
    16921 cggccaaacc attctcatgg taacccactc aacagcagca gctagcagag ctaaacgtgt
    16981 actctttatc aaagacggca ttctttacaa tcaaatctac cgtggagaga agacagaacg
    17041 tcagatgttc caagaaatct ctgatacctt gactgtcatg gcaagcgagg tgaattagta
    17101 tgtttcgatt aaccaataag ttagcggtat cgaacttgat taaaaaccgc aaactctact
    17161 atccttttgc gctggctgtt ctcttggcag tcactgtcac ctatctcttt tactctctaa
    17221 ccttcaatcc taagattgcg gaaatccgtg gaggaacaac cattcaggct acacttggat
    17281 ttggtatgtt tgtcgtcacc cttgcgtcag ccattatcgt tctctatgcc aatagttttg
    17341 tcatgaagaa ccgttccaag gaactaggaa tttatggcat gttgggcttg gagaagcgtc
    17401 atcttatcag tatgaccttt aaggagttag tggtatttgg gattctaact gttggagcgg
    17461 gtatcggtat tggagccttg tttgacaagt tgattttcgc tttcctactc aaactgatga
    17521 aattgaaggt ggaactggtc gctaccttcc agatgaaagt tgtcattaca gtacttcttg
    17581 tcttcggttt gattttccta ggcctcatgt tcctgaatgc ccttcgaatc gcccgtatga
    17641 atgccctcca gctctcacgt gagaaagcta gcggagagaa aaaaggtcgc ttccttcctc
    17701 tccaaactat tcttggttcc ataagtttag ggattggata ttatcttgcc cttacggtaa
    17761 aagatcctct tacagcctta acaaccttct tcctagctgt tttactggtt atctttggta
    17821 cttatctttt gttcaatgca gggattaccg ttttccttca aatcttaaag aaaaataaga
    17881 aatactatta ccaacctaat aatctcatat ctgtttctaa cttgattttc cgtatgaaga
    17941 aaaatgcagt tggactagca actatcgcta ttttgtcaac aatggttttg gtaaccatgt
    18001 cagcagcgac aagcattttc aattccgcag aatcctttaa aaaagttcta aatcctcatg
    18061 attttggggt ttcagggcaa aatgttgaaa aagaagattt ggacaaactc ttgagccagt
    18121 ttgcaagtga caaaggttat aagattaaag agaaagaagt gcttcgttac agtaactttg
    18181 gtattgcaaa tcaagaagga accaagttaa ctatttttga aaaaggacaa aaccgtgtcc
    18241 aaccaaaaac agttttcatg gtatttgacc aaaaagatta tgaaaatatg actggtcaaa
    18301 aactgtctct atcaggaaat gaggtcggtc tctttgccaa aaatgacgga ctgaaaggac
    18361 agaaagctct aactctaaat gatcatcaat tttctgtcaa agaagaattt aataaagatt
    18421 tcattgtcaa ccatgttcca aataagttta atatcttgac tactgattac aattaccttg
    18481 ttgttcctga tttacaagcc tttttggatc aattcccaga ttcggctatc tataatcagt
    18541 tttacggtgg tatgaatgta gatgccagcg aagaagaaca actcaaggtc gctgaggagt
    18601 atgaaaacta cctcaatcaa tttaatgctc aattagacac agaaggtagc tatgtttatg
    18661 gtagcactct agcagatgct agtgctcaga tgagtgccct ctttggtggt gtcttcttta
    18721 tcggtatttt cctatccatt atctttatgg tcggaactgt tctggtcatc tactacaaac
    18781 aaatttctga aggctacgaa gaccgtgaac gctttattat cttgcagaaa gtcggtttgg
    18841 accaaaagca aatcaagcaa accatcaaca aacaggtttt aactgttttc ttccttcctt
    18901 tgctctttgc cttcctacat ctagcctttg cctaccatat gcttagcctg attttaaaag
    18961 tgattggtgt actggatacg actatgatgt tgattgtgac cttgtctatc tgcgctatct
    19021 tcctcatcgc ctatgtgctg atttttatga ttacttcaag aagttatcgc aagattgtgc
    19081 aaatgtaaaa aagataccta gacttcaaaa tcgaggtatt tcttgtattc taaatgctga
    19141 aaagttgttc gagcaggaag gtaactccca tggtcaagag accaatagca aggttccgaa
    19201 tcatagctgt tttggttggg gcttttccaa gtctagcact tgtgtaacca gtgagaagaa
    19261 gggccacacc gacaataagg acggtagcag ggatgcggta atcacttgga aaaatggtca
    19321 ctgacagcat tggaggcaaa cttctaagga aaaaggcaac gaagctagaa atggcagcgt
    19381 gccaaggatt ggtaaattct tcatactcaa tcccatattt ttcctctacc agagccttga
    19441 gtggattttt aagaaagatc ttattagtca agagttgggc agaagttttg aattctccat
    19501 tttggatata agaagcatag agggattttt tggctagttc cctatcttgg tctagcaaga
    19561 gtttttctcg cgaaacggca gcttcctcgg tatcttttgg agttgaaacg gatacatatt
    19621 ctccaccagc cattgaaaag gcaccagcta agatagccgc aaaacctgat aaaaagataa
    19681 tccagatatt gctcgtggca ctggcaactc cgataaccac accagcaatg gaaataattc
    19741 catcgttagc atcaagaaca cccgcacgca ggatatttaa acgacctgca aaatttgaat
    19801 caatttcgtg atttgtttct gacgctaaat ttcaagttca agttagccat ccagaagtct
    19861 tctctgggtg acttgtagtc caagcatttt ttaggatagt tgttaatcca cttttcgatg
    19921 aatgcgactt ctttgggagt cattttcttg attcccttag gtaaccatct acgaatgagc
    19981 ctgttgtgat tctcattagt tcccctttcc caagaggcat aggggtgcgc ataatagatg
    20041 tgctcctcag aaaatacatc aaacaagcga ttgaattccg ttccattatc tgccgtgatg
    20101 gaaagaatct tgtgttgttt taagatgagt tttagagcct gattgaccac atcagcactt
    20161 ttatttggaa tcaatcggat gatctgatgt ctactctttc gatcagtcaa gacaagcaaa
    20221 cagtagtttt tcgctctcgt aagtagaacc gtatcaatct cataatgccc attctccaag
    20281 cgaagattga tagcttcaga ccgctgttcg atggattgac cagcaggttt aaagttggtg
    20341 ctagcctgtt tcttaagcgc ttttcctttt ctagggtaaa gcagatcctg tttgcttaac
    20401 cccaattttc ca
//
LOCUS       DAVIME010000036        20097 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVIME010000036 DAVIME010000000
VERSION     DAVIME010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.036"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            17..970
                     /locus_tag="VV588_001462"
     CDS             17..970
                     /locus_tag="VV588_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7083788.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            1047..3035
                     /gene="uvrB"
                     /locus_tag="VV588_001463"
     CDS             1047..3035
                     /gene="uvrB"
                     /locus_tag="VV588_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU7083789.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            3045..3608
                     /locus_tag="VV588_001464"
     CDS             3045..3608
                     /locus_tag="VV588_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083790.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKMNDGYYQINGNS"
     gene            3574..4083
                     /locus_tag="VV588_001465"
     CDS             3574..4083
                     /locus_tag="VV588_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7083791.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            4136..4603
                     /locus_tag="VV588_001466"
     CDS             4136..4603
                     /locus_tag="VV588_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU7083792.1"
                     /translation="MSRSQLTILTNICLIEDLETQCVVMQYRAPETNRWSGYAFPGGH
                     VENGEAFAESVIREIYEETGLTIQNPQLVGVKNWPLDTGGRYIVFCYKATEFTGTLQS
                     SDEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(4600..5115)
                     /locus_tag="VV588_001467"
     CDS             complement(4600..5115)
                     /locus_tag="VV588_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU7083793.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHQVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(5127..5654)
                     /locus_tag="VV588_001468"
     CDS             complement(5127..5654)
                     /locus_tag="VV588_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU7083794.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(5936..6499)
                     /locus_tag="VV588_001469"
     CDS             complement(5936..6499)
                     /locus_tag="VV588_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU7083795.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(6483..7034)
                     /gene="coaC"
                     /locus_tag="VV588_001470"
     CDS             complement(6483..7034)
                     /gene="coaC"
                     /locus_tag="VV588_001470"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU7083796.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(7046..7735)
                     /gene="coaB"
                     /locus_tag="VV588_001471"
     CDS             complement(7046..7735)
                     /gene="coaB"
                     /locus_tag="VV588_001471"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU7083797.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            7965..9635
                     /locus_tag="VV588_001472"
     CDS             7965..9635
                     /locus_tag="VV588_001472"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU7083798.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            9963..11138
                     /gene="mutY"
                     /locus_tag="VV588_001473"
     CDS             9963..11138
                     /gene="mutY"
                     /locus_tag="VV588_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU7083799.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            11193..11897
                     /locus_tag="VV588_001474"
     CDS             11193..11897
                     /locus_tag="VV588_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083800.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            11890..13239
                     /gene="vicK"
                     /locus_tag="VV588_001475"
     CDS             11890..13239
                     /gene="vicK"
                     /locus_tag="VV588_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU7083801.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            13241..14050
                     /locus_tag="VV588_001476"
     CDS             13241..14050
                     /locus_tag="VV588_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU7083802.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            14141..14383
                     /locus_tag="VV588_001477"
     CDS             14141..14383
                     /locus_tag="VV588_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU7083803.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            14385..14639
                     /locus_tag="VV588_001478"
     CDS             14385..14639
                     /locus_tag="VV588_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU7083804.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            14686..15381
                     /locus_tag="VV588_001479"
     CDS             14686..15381
                     /locus_tag="VV588_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEU7083805.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(15730..16716)
                     /locus_tag="VV588_001480"
     CDS             complement(15730..16716)
                     /locus_tag="VV588_001480"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU7083806.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            16910..19378
                     /gene="gyrA"
                     /locus_tag="VV588_001481"
     CDS             16910..19378
                     /gene="gyrA"
                     /locus_tag="VV588_001481"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU7083807.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            19378..>20097
                     /gene="srtA"
                     /locus_tag="VV588_001482"
     CDS             19378..>20097
                     /gene="srtA"
                     /locus_tag="VV588_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU7083808.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFN"
BASE COUNT         6115 a         3517 c         4505 g         5960 t
ORIGIN      
        1 aaaagaggac ggggatatga agaataaaag aatatttaaa gacttccaag cttcaaaaat
       61 gaatttaaac atttacacaa gccccttgtt agcctttgtt tttgttttca taggagagtt
      121 tgtggcttat actttatatg gtattagttt gttagctctc atcggacttg ctagaaattt
      181 tggagaggct ggtcaaaatc ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga
      241 taaaacaagt gactttcgtt taattttagg attactggcc tttggtttta ttcttaacac
      301 tgtgttcaga tggacaagaa aagttgagaa aagacctatt cgaaccttgg gattttatag
      361 agagaatttc ctcagcaatc ttctgaaagg atttagtcta ggcctggcac tttttcttct
      421 gaccttgtta ggtttagtgg tcttaggtca atatcgtttg gaatccattc acttgaatcc
      481 ttattctctt gcctttgtcg tctttactat cccattttgg attttacagg ggacagcaga
      541 agaagtggtg gcccgtgctt ggctacttcc tcaattggcc tcaagaacca atctaaaact
      601 agctattctt atatctagcc tgttctttac cctgcttcat atgggcaatt ctggcctcac
      661 ccctctatct ctagtaaatc tctttttatt cggagttgcc atggctcttt accttctcaa
      721 aactgataca gtttggggtg ttgcaggtat tcatggtgct tggaattttg ctcagggtaa
      781 tctctttggg attttagtta gtggtcaacc gtcaggaacg tctctgatga cctttttacc
      841 acaaggcaat caagattggc tatcaggtgg ttcttttggc atagaaggtt ccattatgac
      901 aagtctggta ttactactgc tgattgtcta tcttgctaat aaattaaaga aagaaaatga
      961 aaggatgtga cttcggtccg tccttttctt cgtgaaaata ctataagtat gctaaaatag
     1021 gaatagcaca tggagagagg attcttatga tcaatcacat tacagataat caatttaaac
     1081 tagtatcaaa atatcaacca tcaggagatc aaccccaagc tatcgagcag ttggtggata
     1141 acattgaggg gggagaaaaa gctcagattc tgatgggggc gactggaaca gggaagacct
     1201 atactatgag tcaggtcatt tctaaagtca ataaaccaac tctggttatt gcccacaata
     1261 aaactctggc tggtcagctc tatggggagt ttaaggaatt tttccctgaa aatgcagttg
     1321 agtatttcgt atcctactat gattattacc agccagaggc ctatgtccct tctagcgata
     1381 cctatattga gaaggatagt tctgtcaatg acgagattga caagcttcgc cactcagcta
     1441 cctcagccct tttggagcgt aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg
     1501 gtttgggttc gcccaaggaa tacgctgata gtgtcgttag tctccgtcct ggtctagaga
     1561 tttctcgtga taaactcttg aatgacttgg tcgatattca gtttgaacgc aatgatattg
     1621 atttccaacg cggaagattt cgcgttcgtg gggatgtggt agagattttc ccagcttccc
     1681 gagatgaaca tgcctttcga gtagaatttt ttggagacga aattgaccgt attcgtgaag
     1741 ttgaggctct gacaggtcag gtgttgggag aagtggatca tttagcgatt ttcccagcga
     1801 cacactttgt gaccaatgac gaccacatgg aagttgccat tgcaaagatt caggccgagt
     1861 tggaagaaca attagctgtc tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga
     1921 aacagcggac agagtatgat atcgaaatgt tgcgtgagat gggctatacc aatggggttg
     1981 aaaattattc tcgccacatg gatggacgga gcgaaggaga gcctccttat acgcttctcg
     2041 acttcttccc agatgatttc ttgattatga ttgacgagag tcatatgacc atagggcaaa
     2101 tcaagggcat gtacaatgga gaccgttcgc gtaaagaaat gctggttaat tatggtttcc
     2161 gtttgccgtc tgctttggac aatcgtcctc tacgtcggga ggagtttgag agtcacgttc
     2221 atcagattgt ttacgtttca gcgacacctg gtgactatga aaatgaacag accgagacag
     2281 tgattgagca aatcattcgt ccaacgggac tcttggatcc agaggtggaa gtccgtccga
     2341 ctatgggaca gattgatgac ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc
     2401 gtacctttat cacaactttg accaagaaaa tggcagagga cttgaccgac tacttcaagg
     2461 aaatgggtat caaggtcaag tacatgcact cggatatcaa gaccttggaa cggacggaga
     2521 ttatccgtga cctgcgcttg ggtgtctttg atgtcttggt cggaattaac ctgctccgtg
     2581 aaggaattga cgttcctgaa gtgagcctcg tagctattct cgatgctgac aaggaaggtt
     2641 tccttcgcaa cgaacgtgga ctcatccaga ctattggacg tgctgctcgt aacagtgaag
     2701 gccatgtcat catgtatgca gacacggtta cccagtctat gcaacgtgct atcgatgaaa
     2761 ctgcccgccg tcggaaaatt cagatggcct ataatgaaga gcatggtatc gtaccacaga
     2821 caatcaagaa agaaatccgt gacctgattg ccgtgaccaa ggcagttgct aaggaagagg
     2881 acaaggaagt cgacatcaat agcctcaaca aacaagagcg caaagaactc gtcaagaaac
     2941 tagaaaaaca aatgcaagaa gccgtcgaag tgcttgactt tgaactggcg gctcagatcc
     3001 gtgatatgat gttggaagtc aaggccttgg attaggggaa tagtatgatt tatttaagaa
     3061 agttaaagag agaagatttg atgtctttat gggaaatggc ttattcacaa cttaatccag
     3121 tttggaaaca gtatgatgct ccctattatg atgattatca gtatttttca aattttaaag
     3181 aattcgaact acaaaaatca gaatccattt taagcaactc aaatcgcctt ggtatttttg
     3241 ttgatgataa actagttggg actgtttcgc gttattgggt atgtaaacaa acaagatgga
     3301 tggaattggg aattggtatt tatgataaaa aattctggaa cactggtatt gggaaagttg
     3361 ctatgttgca gtggatagat aggacgtttc aggattactt ggagttggag catctgggtt
     3421 tgacaacttg gtcaggaaat cttggtatga tgaaacttgc tgaaaaatta agaatgaaaa
     3481 aagaagctca tattccaaaa gttcgttatt atcaaggtaa atattttgat agtattaaat
     3541 atggtatttt gagagaagac tgggagaaaa tgaatgacgg ttattatcaa atcaatggaa
     3601 actcctgaag agatagaagg taaatccctt gttcactggc aaacgtggag agaggcttat
     3661 gatgaccttt tgcctgcaga atttcaggag acaatgacat tagaaagatg tcgattcttt
     3721 agtcaaaagt atccagaaaa tacattgatt gcgataggtg atctgaaggt agttggtttt
     3781 atcagttatg gtaactttcg tgatgagact attcaagctg gtgaaattat tgctttatat
     3841 gttttaaaag actattacgg aaaaggcata gcacaaaagt taatgaaagc agctttgact
     3901 gctctgaatc atttttctga aattttctta tgggtattga aagataacaa gcgagccatt
     3961 gctttctatc aaaaaatggg ttttactttt gatggacaag aaaagatact tgaacttgga
     4021 aagcctataa aggaaaaacg aatggtattc tattctaaaa taattttaaa aagtagaagc
     4081 taatggcact ggtaccaagt ctgaaaattt aataaattag aaagcgagta aatttatgtc
     4141 ccgttcccaa ttaacgattt taacaaatat ttgtctgatt gaagaccttg aaactcagtg
     4201 cgtggttatg cagtaccgtg ctcctgaaac caatcgctgg tctggttatg cctttcctgg
     4261 aggtcatgta gaaaatggtg aggcttttgc ggagtctgtc attcgtgaaa tctacgaaga
     4321 aacaggattg actatccaaa atccgcaact ggtaggtgtt aaaaattggc ctttggatac
     4381 aggggggcgc tacattgtct tttgttacaa ggcgaccgag tttactggaa ctcttcaatc
     4441 ttcagacgag ggagaagttt cttgggtgca aaaagaccag attccaaact tgaatctggc
     4501 ctatgatatg ctaccattga tggaaatgat ggaagctccc gacaagtcag agtttttcta
     4561 ccctcgccgt acagaagacg attgggaaaa gaaaatcttc tagtctttta ctaaataacc
     4621 tagctgatcc aaggcttcct cgatatagtg gaggtcttgt tgtgtttcgg cttcgactag
     4681 gtggtaatgg atgccatctg tcaattcaga tagaggtcta aagtcagaat gctcgacttg
     4741 ttctagaaaa tgttgcacat ctctgcgaca agacagttta agcaaggttt caatttctcc
     4801 ataaacggga tggtcaatca aggtattctg gacatgccca ccattatcga caatagcaag
     4861 gagttcctga ccgatttctt caacttgatg tttcactttg aaaagtttgt gaacataagg
     4921 attggtatca atttgcttat agatgtagcc acgattggtg gataggatag gagcgccatc
     4981 ggctctcaaa attgcaatgt cctgcacaat gacctgacgt gtgacatgaa aatgttccgc
     5041 caaactttgg ccattaaggg ctttaggagc ttctttcaag agttggagca gggcttgttt
     5101 gcgatctttt gtcatagctt ttccttttaa cggcgttttc gaagcacttt atagacagct
     5161 agtgctaatg tatagtctac catactatgg ataattgtgc caaatccaac tagtacaaat
     5221 agaacataga acatgttttc tacattggta cccgaagttg cgtaaaaaag gacacaggct
     5281 aatacttcag caagggcatg aacaacagcc aaaacaaaat tgaaaaccca ggaagatttt
     5341 ggtttatcta gggtatcggg gaatttttgt aggtaaagag ctcctaaagc accaaaagat
     5401 atatgggaaa aagcccgaaa aacgataacc atgggatagc cagccatcaa aaatccaaaa
     5461 ctagaggcta ggatgacaaa aactgccatc aagggcgaca agaacatggc tataaaaata
     5521 gcgatgtggc tccccaaagt ataggaagca ggtggaatga caatcttgaa aggcataaca
     5581 attggaatca aaatcgcaat agccgttaaa agggctgtca ttgtcataaa ttgtgtcttt
     5641 ttccgtgtat tcacaagaat ctccttttta actgcatata cactagtatg gtacaataaa
     5701 ccagacaata aagcaagaat ttacttgggt ttatagatca ttttttagtt aaaagttata
     5761 gtagattgaa actagaatag tacacctcta cttctaaaac attgttagaa atcgatttga
     5821 ctgtcctgat cgatttgtcc tgttcttatt tcgttttact atagtaaaga tttcattaaa
     5881 aagaaactgt atagagcaaa atctccacct tcaggtttga aagcggagat tgtttttatt
     5941 ttttcaaggt ttgtagtcgt ggaacaatgg ctagggttag aattgcagaa atgaccaatt
     6001 cagcaattga atttgttgag ataacggttg ccagaagaag ttggatattt ccattataaa
     6061 catttccaaa taggaagaag attcctccaa ggacaaagat agtatttgtc aaggaaccaa
     6121 gggctccagc taaaatcaga ccagtcttgt ttttcatcag tttatagact aagtaaggag
     6181 ttaaaccaat caaaatacgt gggacgatgg caatgatagc tgagtagatg tttccgtttg
     6241 gtacgaaggg agagaagagg tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc
     6301 taagtagccc catcaaaaat ccaagtgtaa ccccaactcg tggaccataa ataatgctgg
     6361 caataatgac aggaatatga acaatggtcg gtttgattgg aaatggaaaa aggttaaaga
     6421 taagtgagct cagaaagtgt atcacgagca tggtagcaaa aaagatagca atgggtgcaa
     6481 tattagagcg ttttttcatc gagagtttcc tttattcttt ctaaaataat tgtgaggtca
     6541 gctaaagctc ctcgtccgtg gtctccacaa gctagtaggg attccttagg agcaatcagc
     6601 tgatagccgt aggtttctaa tgttttcaga ttattctgag ttactggatg gtcatacatt
     6661 tttgtattca tagcaggagc tattagtttg ggaatatgac ttggcagggc tagagctgta
     6721 ctggttacca tgttgtccgc aaatccgtga gctagttttg caatagtgtt agcagttgca
     6781 ggtaccacga taaataaatc tgcttttttt ccaagttcga tatgattgac ctgatcagga
     6841 tagggttcct tcatgacatc caagtggaca ggattctgtg agagtacctg tagtgtcaaa
     6901 ggttggataa actctgtagc agcctgagtc attaagacag tgacttgatg gccttgtttt
     6961 tttagagaac tgactaaatc tgccgactta taagaggcga ttgaacccgt tacagccaag
     7021 agaatgtttg ccatagtttt cctttctaag aatgataggc ttgaattttt tcaaggagga
     7081 gttctgcaat ttcttcttta gtctggactg tttgaagctg atttttctca acaaatatag
     7141 ctcggtgctg acctgctgaa atttgagtca ggtcattcgc gatgattaaa tctgcttgat
     7201 tcttgataag actttttcgt gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca
     7261 gtttgaaacc aatcagatga atagtaggat tccattcctt gactagggat atgattttgg
     7321 gtgtcttttt aaggaacaaa acctgaacct catcagttga agaaatcttg gcctgatgat
     7381 tctgcttgct taaaaattct tttagattgg agctagcctg aacttcctca agccctgtca
     7441 tataaacagg agtgtagtca gaaacagcca ttgagtggat caagacctga taatcctgaa
     7501 cacgttcttg catttctatt agaaggtcct tggtattggt aatttctcga atacttaggt
     7561 taggatgagg ctctggcttc agagctcgtt ttgtcgtaat taaacaaact tcatgccctg
     7621 caaaaagcaa agtctctgtg ataattttcc ccaagtgacc tgtagaatgg ttagtgatag
     7681 agcggacgct atcgatagct tcactggtac cgcccgatgt aactaaaatt ttcatagcac
     7741 tattgtacac aaaaataagc ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga
     7801 agatttacta tagtttcaaa ctataaaacc atataaaatt taagaaagga ctctaaaagc
     7861 cttaaaaaca gagatattta cgaacgttta gagagtttta ggatgttaaa aatcttgttt
     7921 tgtgatataa tgaattatca tataagaggt tagaggaatt ttgaatgaaa acagatattg
     7981 aaatcgcaca gagtattgag ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt
     8041 cttatgacga tttggagttg tacggaaagt acaaggctaa actcagcttt gataaaattc
     8101 gtgcagttga gagcaatcca gtcggtaaat tgatcttggt tactgccatc aacccaacac
     8161 ctgcaggtga aggaaagtcg acacttacca ttggtcttgc ggatgccttg aacaagattg
     8221 gcaagaaaac catgattgct atccgcgaac cgtctcttgg tccagtcatg gggatcaagg
     8281 gtggtgctgc tggtggtggg tatgcacaag ttctgccaat ggaagacatc aacctccact
     8341 ttactggaga tatgcatgct attacaactg ccaacaatgc cctttctgcc ttgattgaca
     8401 accacttgca ccaagggaat gagctggaaa ttgatcaacg tcgtatcctc tggaaacgcg
     8461 ttgtggactt gaacgaccgt gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa
     8521 acggtattcc acgtgaggat ggttttgata ttacagttgc ttcagaaatc atggcaattc
     8581 tttgcttggc aacggacatc gaggacttga aacgtcgttt ggcgaatatc gttattggtt
     8641 atcgctatga ccgtacgcct gtttctgtag gtgatttgca ggttgagggt gccttggctt
     8701 tgattttgaa ggatgctatt aagccaaact tggttcagac aatttacggt acacctgcct
     8761 ttgtacacgg tggtccattt gccaatatcg ctcatggctg taactctgtt ttggcgacga
     8821 caacagccct tcacttggct gattacactg ttactgaagc tggttttggt gcggaccttg
     8881 gtgctgagaa attccttgat atcaagacac caaacttgcc aacatctcca gatgcagttg
     8941 ttattgtcgc aacccttcgt gcccttaaga tgaatggtgg tgtggctaaa gacgctctga
     9001 ctgaagaaaa tgtagaggca gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa
     9061 atatccgtaa gttcggtatt ccagcagttg tagctattaa cgaatttgta tctgatacag
     9121 aagctgaaat tgcagcctta aaagaactct gtgcctcaat cgatgtacca gttgaattgg
     9181 ctagtgtctg ggctgatgga gcagaaggtg gagtagcact tgccgaaaca gttgttaaga
     9241 caattgctga aaatccagct aactataaac gtttgtacga taatgacctt tctgtccaag
     9301 aaaagattga aaaaattgtc actgaaatct atcgtggtag caaagtgaac tttgagaaga
     9361 aagctcaaac acaaattgct caaatcgttc aaaacggttg ggacaaattg ccaatctgta
     9421 tggctaaaac tcaatacagt ttctcagaca atccaaatgc gcttggagca ccagaaaact
     9481 ttgaaattac cattcgtgaa ttggtaccaa aattaggtgc aggcttcatc gttgccttaa
     9541 ctggtgatgt tatgaccatg ccaggtcttc caaaacgtcc agcagctctc aacatggatg
     9601 ttgaaagcga tggaactgta ctaggcttgt tctagtggat tgaaattgac tttaagtgag
     9661 tttggaaata atatccaagc tcattttttc tcagactgca agcagttcat caataagatt
     9721 tatactcttc gaaaatctct tcaaactacg tcagcttcac cttgccgtag gtatatgata
     9781 ctgactctgt cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgcggctagc
     9841 ttcctagttt gctctttgat tttcattgag tataagtaga tagaaaagtt atatactatc
     9901 tattgaaaat attataaatc agatacaaag acaggtgaaa ccttctgtgt tatactagag
     9961 atatgttaga tttgaaagaa tacggtatcg tcatgtggcc ggaggagaaa gtcatttctt
    10021 tccgtgagaa acttctcgct tggtatgatg aaaacaaaag agatttgcct tggaggagaa
    10081 gtaaaaatcc ttatcacatc tgggtatctg aaatcatgct tcagcagacc agggtggata
    10141 cagttatccc ttactacgaa agattcctgg actggtttcc aactgtcgaa agtctggcaa
    10201 ctgcgcctga ggagagttta ctgaaagctt gggagggctt gggctattat tctcgagttc
    10261 gcaatatgca ggctgcagcc cagcagatta tgactgactt tggtggccaa tttccaaata
    10321 cctatgaagg aatttccagc ttgaaaggga ttggacctta cacagcagga gccatttcca
    10381 gtattgcttt taacttgcct gagccagctg tagatggtaa tgtcatgcgg gtcttggcgc
    10441 gtctgtttga agtcaaccac gatattggga ttccaagtaa tcgaaaaatt tttcaggcaa
    10501 tgatggagat cttgattaat ccggatcgtc cgggtgattt taatcaagcc ttgatggact
    10561 tagggtctga tattgagtct cctgtaaatc ccagacctga agaaagccca gtcaaggact
    10621 ttagtgcggc atatcagaat ggaaccatgg accgttatcc aattaaatct cctaagaaaa
    10681 agccggttcc tatttatctt aaagccttag ttgtgaaaaa ttctcaagga caatttttac
    10741 ttgaaaaaaa tgaaagcgaa aagctcttgg caggtttttg gcatttcccc tttatagaag
    10801 ttgataactt ttcgcaagaa gagcagtttg acctctttca tcaggttgcg gaagaaagtg
    10861 tgaactttgg ccccagtcca gaagagagtt tccagcagga ctatgaccta gatgttgatt
    10921 ggcttgatgt ttgttttgat acagtccagc atgtttttag tcatcgaaaa tggcatgtac
    10981 agattgtagc aggtcaggtg agtgacttcc atgatttttc agatagggaa gttcgttggc
    11041 tttcaccaga agaattcaag aattacccac ttgccaaacc ccaacaaaaa atctggcagg
    11101 cttatgcaca agccaactta gacagtagcc aagactagct attgtgtctt ctgactattt
    11161 tttggtataa tagtagagaa aaaggtgaac atatgaaaaa aatactaatt gtagatgatg
    11221 agaaaccaat ctcggatatt atcaagttta atatgaccaa ggaaggttac gaagttgtaa
    11281 ctgcttttaa tggtcgtgaa gcgctagagc aatttgaagc agagcaacca gatattatta
    11341 ttctggattt gatgcttcca gaaattgatg gtttagaagt tgctaagacc attcgtaaga
    11401 caagcagtgt gcccattctt atgctttcag ccaaagatag tgaatttgat aaggttatcg
    11461 gtttggaact tggggcagat gactatgtaa cgaaaccctt ctccaatcgt gagttgcagg
    11521 cgcgtgttaa agctcttctg cgtcgttctc aacctatgcc agtagatggt caggaagcag
    11581 atagtaaacc tcaacctatc caaattgggg atttagaaat tgttccagac gcctacgtgg
    11641 ctaaaaaata tggcgaagaa ctagacttaa cccatcgtga atttgagctt ttgtatcatt
    11701 tagcatcgca tacaggtcaa gtcatcacgc gcgaacactt gcttgagact gtctggggtt
    11761 atgactattt tggtgatgtc cgtacagttg atgtgactgt acgacgtctg cgtgagaaga
    11821 ttgaagatac gcccagccga ccagagtata tcttgacgcg ccgtggagta gggtattaca
    11881 tgagaaataa tgcttgattt actgaaacaa accattttta ccagagattt tatctttatc
    11941 ctgattttgt taggtttcat ccttgttgtg accctcttat tactggaaaa tagacgtgat
    12001 aatattcagt tgaagcaaat caatcaaaag gttaaagatt tgattgcagg agattattcc
    12061 aaggttcttg atatgcaagg tgggtctgaa atcaccaata ttaccaataa tttgaatgac
    12121 ttgtcggagg ttattcgtct cactcaggaa aatctagaac aagagagtaa gaggctaaat
    12181 agtattctgt tttatatgac agatggggtt cttgcgacca accgtcgggg tcagattatc
    12241 atgattaacg atacagccaa gaagcaactg gggttggtta aggaagatgt tctgaataga
    12301 agcattttgg aattgctcaa gatagaagaa aactatgaat tgcgtgattt gattacccaa
    12361 agtccagaat tgttgctaga ttcccaagat atcaatggcg aatatttgaa ccttcgagtt
    12421 cgctttgcct tgatacgtcg agagtctggc tttatttcag gtttggtggc tgttttgcat
    12481 gatacgacgg agcaggagaa ggaagaacgc gaacgaagac tctttgtttc caatgttagc
    12541 catgagttac ggactcctct gactagcgta aaatcctatc ttgaagcctt ggatgagggg
    12601 gctttgtgtg aaactgtagc accagacttt atcaaggttt ctcttgatga gaccaaccgt
    12661 atgatgcgca tggtgacgga tctcctccat ctttcacgta ttgataatgc taccagtcac
    12721 ctagatgtgg aactgattaa cttcactgct tttattacct ttatcctcaa tcgttttgac
    12781 aagatgaaag gacaggaaaa ggagaaaaaa tatgagttgg tgagagatta tcccatcaat
    12841 tctatctgga tggaaattga tacagataag atgacgcagg ttgtcgacaa tattttaaat
    12901 aatgctatta agtattcgcc agatgggggt aaaatcactg tcagaatgaa gacaactgaa
    12961 gaccagatga ttttatccat ttctgaccac ggtttgggga ttcctaagca ggatttacca
    13021 cgtatctttg accgtttcta tcgtgtggat cgtgctagaa gtcgtgcgca aggtggtaca
    13081 ggtctaggac tgtctatcgc taaagaaatt atcaaacaac ataagggctt tatttgggcc
    13141 aagagtgaat acggcaaggg ttcaaccttt accattgtgc tcccttatga taaggatgca
    13201 gtgaaagaag aagtatggga ggatgaagta gaagactaga atgagtgaaa taggctttaa
    13261 atacagtatt ttagcgtcgg gttccagtgg aaattctttt tatctggaaa cctcaaaaaa
    13321 gaagctttta gtagatgcag gcttgtctgg caagaaaatt accagtctgc tagctgaaat
    13381 taaccgtaag ccagaagacc tggatgccat cttgattacc catgagcatt cagatcatat
    13441 ccatggagta ggcgttttgg ctcgcaagta tggtatggat ctttatgcca atgaaaagac
    13501 ctggcaagct atggaaaata gtaaatatct tggcaaggtg gattcttcgc aaaagcatat
    13561 ttttgaaatg ggtaaaacca aaacctttgg agatatcgac atcgagagtt ttggtgtaag
    13621 ccatgatgca gtcgcaccgc agttctatcg ctttatgaag gatgataaga gttttgtcct
    13681 tttgacagat acaggttatg tcagtgaccg tatggcgggc attgtcgaaa atgcggatgg
    13741 ctatcttatc gaggccaacc atgatgtaga gattttgcga tcaggttctt acgcttggcg
    13801 actcaaacaa cgaatcctat ctgaccttgg tcacctttct aacgaggacg gtgctgaagc
    13861 tatgattcgg acgctaggaa atcgtactaa gaagatttac cttgggcatt tatctaagga
    13921 aaataatatc aaggaactgg ctcatatgac catggtcaat cagctggctc aagctgatct
    13981 gggagtcgga gtagacttta aggtttatga tacctcacca gataccgcaa caccattgac
    14041 agagatatag aaagaacgct gagaaggtgt tctttttata ttgactgaac acctaaaaag
    14101 taatacaatg gtgttaccat taaaaaaggg agcacaaaag atgactacta ttacattaaa
    14161 agtttctgaa gctgataaaa catttatgaa agcaatggct aagtttgaag gagtttccct
    14221 ttcggaactt attcgcacca aaactcttga agccctagaa gatgaatacg atgctcgtgt
    14281 ggcagattta gcctatcaag agtatttaga agacttggaa aaaggagttg aacccattac
    14341 ttgggaagaa atgatgcatg atttaggctt gaaggatgaa taatttgtat aaattagttc
    14401 caacaagacg ttttatcaag caattgaaaa aattggaccg ttatacgcag aagctaatta
    14461 caaactattt acaaaccaat gttttggaag gtccaagacg acacggaaag gctttggttg
    14521 gtaatcgcgt tggtcaatgg cgctatagaa ttggtaatta tcgagttatc gtacaaattg
    14581 tagatgatga attagtcgtt gctactctag aagttggtca tcggagagat atttattgaa
    14641 ttaaagctga gtaataacaa tatagaaagt aaggagagta aaaatttgaa gaaaaaatgg
    14701 ttatttgcag attattatga tacaacaatt attttacttg ctttaatctc tgttattctg
    14761 gtattacttg gatttgctga gatgactgat ttggacaatc cgccttatag tattattgat
    14821 ttagtaatct ggggtgtttt tgtaattgat tatagttggc gcttttttat tactaaaaga
    14881 aaatggcgct ttattcttga aaatattttt gatttattga ccattctccc tttaaatgct
    14941 atttttacag tgtttcgatt aggacgtatc ttccgcttag caaggctgac aaaattactg
    15001 aaactgactc gtttacttag aataattgga cttacaggta aactagaaag aaaaattagt
    15061 agattcttac gaacaaatgg attgatttat atcttgtatg ttaatatctt tattgttcta
    15121 gtagggagtt cgattttatc cgttgttgaa gaaaaatcct tctcagatag tctttggtgg
    15181 gctcttgtga cagtaactac tgttggttat ggtgatattg ttccagtttc cctttttggg
    15241 aaatggctag cagttttact gatgcttgtc ggtattggaa caatagggat gctaacaagt
    15301 gctttgacga acttttttgt aaaggataat ccagatgaac agataaaact tgataaactc
    15361 aaagacgaat tatcgagcta aagaatatta atagagaaac aatctgaaaa aatcgaagaa
    15421 ctacattgaa tgataaaaga cttagttgaa aaaatatcat aaaggtgaga caaaataaaa
    15481 cttgattcga ggagaaatca agtaagtttt gacacaatag aacgcatatt atcaggtata
    15541 aaaacttgat actatgcgtt ttatagagaa ataaaataaa atctgaacaa atcaattagg
    15601 aatttaaagc attttataac aacgttttag agtaatgggg tgctatttca acttcaacct
    15661 actataatac agaaaaaaat acagaaaaaa acaactccct gatgattcaa ggagttgtct
    15721 atagttaaat tagtttttag aagcttcttg gaattctgga tttttccatg cttcgtcaat
    15781 aatagcttgc aattctttag cagatgcttg cattttttga gtttctgcat cgttcaatgg
    15841 aatgtttact ggacgaacga taccatgtgc accaacaaca gctggttgac cgataaagac
    15901 attctcaact ccgtattgac cttcttggaa tactgaaagt ggaagtactg cgttttcatc
    15961 gtcaaggatt gctttagtga tacgagcaag ggctactgcg ataccgtagt atgttgcacc
    16021 ttttttgttg atgattgtgt aggctgcatc acgaacacct tcgaacaatt caatcaattc
    16081 agcttcttga acattttgag tgtctttaag gaattcttca agatttacac cagcgatgtt
    16141 agcgtgtgac caaacagcga actcagagtc accgtgttca cccatgatgt aggcgtgcac
    16201 tgaacgagca tccacatcca atttttcagc aagtgcttga cggaaacgag ctgagtcaag
    16261 tgaagtacct gaaccgataa cgcgttcttt agggaaacca gagaatttcc aagttgagta
    16321 agtcaaaacg tcaactgggt tagcagcaac aaggaagata cctttgaaac cagattcaac
    16381 aacttgagtt acgattgatt tgttgatagc aaggttttta cctacaaggt caagacgagt
    16441 ttcacctggt ttttgaggtg cacctgcagt gatcacaaca aggtcagcgt ctgcacagtc
    16501 agagtattga gctgcataga tttttttagg tgaagtgaag gcaagggcgt gactaaggtc
    16561 aagcgcatca ccaacagctt tttcatgcaa ttgtggaatt tcgataattc caagctcttg
    16621 tgcaattcct tggttaacaa gtgcaaaagc gtaagatgaa cctacagcac catcaccgac
    16681 aaggataact tttttgtgtt gtttagttga agtcattgtt ttaaacatct ccttaatttt
    16741 attaggggat tttccctaga caacttcatt ctatcacttt taaaaaactt tgtcacgaat
    16801 atgccttata gttctcgatg taaacgtttt agtggtttag aggctgaaat agatgggaat
    16861 ttatggtata atgttgttac ttactaattg tgaaatgagg catttattaa tgcaggataa
    16921 aaatttagtg aatgtcaatc tgacaaagga gatgaaggca agttttatcg actacgccat
    16981 gagtgttatc gtagcgcgag ctcttcctga tgttcgagat ggcttaaaac ctgttcaccg
    17041 tcgcattctc tacggaatga atgaattggg tgtgacccca gacaaacccc ataaaaaatc
    17101 tgctcgtatt acaggggatg tcatgggtaa atatcaccca cacggggatt cctctattta
    17161 tgaagccatg gtccgtatgg ctcaatggtg gagctaccgt tacatgcttg tagatggtca
    17221 tgggaatttt ggttccatgg atggagatag tgctgccgct caacgttata ccgaggcacg
    17281 tatgagcaag attgctctgg aaatgcttcg tgatatcaac aaaaatacag ttgatttcgt
    17341 tgataactat gatgccaatg aacgggaacc cttggtcttg ccagcgcgtt ttccaaacct
    17401 tttggttaat ggagcaactg gtatcgcggt tgggatggca accaatattc cacctcataa
    17461 tctgggtgaa accattgatg cagtgaagtt ggtcatggat aatcctgaag tgactaccaa
    17521 ggacttgatg gaagtcttgc ctggaccaga ttttccaact ggtgctcttg tcatggggaa
    17581 atcaggtatc cataaggctt atgaaacagg taaaggttcg attgtcctac gttctcgtac
    17641 agagattgaa acgactaaga ctggtcgtga gcgtatcgtt gtaacagaat ttccttacat
    17701 ggtcaataaa accaaggtgc atgagcatat tgttcgcttg gttcaggaaa aacgcattga
    17761 gggtatcaca gcagtacgtg atgagtcaaa ccgtgaaggt gttcgatttg ttattgaagt
    17821 caagcgcgac gcctcagcca atgttattct caataacctc ttcaaaatga cccaaatgca
    17881 aaccaatttt ggattcaata tgctcgctat ccaaaatggt ataccgaaaa ttttgtctct
    17941 tcgtcagatt ttggatgctt atattgagca ccaaaaagaa gtggttgttc gtcgtacacg
    18001 ttttgataag gaaaaagcgg aagcgcgcgc tcatatctta gaaggtctct tgattgcgct
    18061 agaccatatc gacgaagtga ttcgtatcat ccgtgctagt gaaacggatg cggaagctca
    18121 agctgagttg atgagcaagt ttaagctttc tgaacgtcaa agtcaagcta tccttgatat
    18181 gcgtcttcgt cgtttgacag gtttggaacg cgataagatt caatctgagt atgatgacct
    18241 cttggctctg attgcggatt tagcagatat tcttgctaag cctgaacgtg tttctcaaat
    18301 tatcaaagac gaattggatg aagttaaacg taaattttct gataaacgcc gtacagagtt
    18361 gatggttgga cagatcttga gtctcgagga tgaggacttg attgaagaat cggatgtctt
    18421 gattaccctt tctaacagag gctacattaa gcgtttggat caggacgagt tcactgctca
    18481 aaaacgtggg ggtcgtggtg tccaaggaac gggagtgaaa gatgatgact ttgttcgtga
    18541 gttagtgtca actagcaccc atgatcatct gctcttcttc acaaacaagg gacgtgtcta
    18601 tcgtcttaaa ggttatgaaa ttcctgagta tggtcggact gccaaagggc taccagtagt
    18661 caatctcttg aaattggatg aagatgaaag tattcagacg gttatcaatg ttgagtctga
    18721 tcgcagtgat gatgcttatc tcttctttac aacccgtcac ggtattgtga agagaactag
    18781 tgttaaggag tttgccaata ttcgtcaaaa tggtctcaaa gcgctgaatt taaaggatga
    18841 agatgagtta atcaatgtct tgttgacaga aggagatatg gatattatca ttggtaccaa
    18901 gtttggttat gcagttcgct ttaatcaatc agccgttcgt ggtatgagcc gtatcgccac
    18961 tggtgtgaaa ggtgttaacc ttcgtgaagg agacacagtt gttggtgcca gcttgattac
    19021 tgatcaagat gaggttctta ttatcacaga aaaaggatat ggtaagcgta cagtcgctac
    19081 tgaataccca acaaaaggtc gtggtggtaa gggaatgcag acagctaaaa ttaccgaaaa
    19141 aaatggcttg ctggccggtc ttatgactgt tcaaggggat gaggatttga tgattatcac
    19201 tgatacaggt gtcatgattc gaaccaatct tgccaatatt tcacaaacag gacgtgcaac
    19261 tatgggagtt aaagtaatgc gcctggatca agatgctcag atagtgactt tcacaacggt
    19321 tgcggtggca gaaaaagaag aagttgggac agaaaacgaa acagaaggtg aagcataatg
    19381 tctcaaaaaa ataataaaaa gaaaaacaag cgaaaaaatc tgctgacaaa tatcctagca
    19441 ggatttctga tattactgtc actggctttg atttttaata ctcaaattcg aaatattttc
    19501 atagtctgga ataccaataa gtatcaagtt agccaggtat caaaagaaaa attagaagaa
    19561 aatcaggata cagaaggcaa ttttgacttt gattctgtca aagctatctc ttcggaagct
    19621 gttctaactt ctcaatggga tgctcaaaaa ttaccagtta ttgggggaat tgcaattcct
    19681 gaattggaaa tgaatttgcc gatttttaaa ggacttgata atgttaatct cttttacgga
    19741 gctggtacaa tgaaacgcga gcaagtaatg ggagaaggaa attatagtct agctagtcac
    19801 catatctttg gtgttgataa tgctaataaa atgttatttt ctcctttaga taatgctaaa
    19861 aatggcatga agatttatct aaccgataaa aataaagttt atacttatga aatacgtgaa
    19921 gtcaaacgtg tgacaccgga tcgtgttgat gaagttgatg atagagatgg ggtcaatgaa
    19981 atcacattag taacctgtga agaccttgct gctacagaac gtattattgt caaaggtgat
    20041 ttgaaagaaa caaaagatta ttcacaaaca tctgatgaaa ttctaacagc tttcaat
//
LOCUS       DAVIME010000037        20075 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVIME010000037 DAVIME010000000
VERSION     DAVIME010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.037"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(85..1026)
                     /locus_tag="VV588_001483"
     CDS             complement(85..1026)
                     /locus_tag="VV588_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU7083809.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VV588_001484"
     CDS             complement(1004..2767)
                     /gene="aspS"
                     /locus_tag="VV588_001484"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU7083810.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(2952..3032)
                     /locus_tag="VV588_001485"
                     /pseudo
     CDS             complement(2952..3032)
                     /locus_tag="VV588_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3074..3304)
                     /locus_tag="VV588_001486"
     CDS             complement(3074..3304)
                     /locus_tag="VV588_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083811.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(3322..3963)
                     /locus_tag="VV588_001487"
     CDS             complement(3322..3963)
                     /locus_tag="VV588_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU7083812.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(3975..4709)
                     /locus_tag="VV588_001488"
     CDS             complement(3975..4709)
                     /locus_tag="VV588_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU7083813.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(4712..4909)
                     /locus_tag="VV588_001489"
     CDS             complement(4712..4909)
                     /locus_tag="VV588_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083814.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(4909..5115)
                     /locus_tag="VV588_001490"
     CDS             complement(4909..5115)
                     /locus_tag="VV588_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7083815.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(5125..5439)
                     /locus_tag="VV588_001491"
     CDS             complement(5125..5439)
                     /locus_tag="VV588_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083816.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(5706..5783)
                     /locus_tag="VV588_001492"
                     /pseudo
     CDS             complement(5706..5783)
                     /locus_tag="VV588_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(5780..7069)
                     /locus_tag="VV588_001493"
     CDS             complement(5780..7069)
                     /locus_tag="VV588_001493"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU7083817.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(7147..8394)
                     /locus_tag="VV588_001494"
     CDS             complement(7147..8394)
                     /locus_tag="VV588_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU7083818.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLDLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(8585..9436)
                     /gene="rgg"
                     /locus_tag="VV588_001495"
     CDS             complement(8585..9436)
                     /gene="rgg"
                     /locus_tag="VV588_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU7083819.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELLV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            9560..9901
                     /locus_tag="VV588_001496"
     CDS             9560..9901
                     /locus_tag="VV588_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU7083820.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIEDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            9959..10039
                     /locus_tag="VV588_001497"
                     /pseudo
     CDS             9959..10039
                     /locus_tag="VV588_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10155..11858)
                     /gene="ilvD"
                     /locus_tag="VV588_001498"
     CDS             complement(10155..11858)
                     /gene="ilvD"
                     /locus_tag="VV588_001498"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU7083821.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIIDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(12091..13023)
                     /locus_tag="VV588_001499"
     CDS             complement(12091..13023)
                     /locus_tag="VV588_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU7083822.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(13020..13877)
                     /locus_tag="VV588_001500"
     CDS             complement(13020..13877)
                     /locus_tag="VV588_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU7083823.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(13881..15227)
                     /locus_tag="VV588_001501"
     CDS             complement(13881..15227)
                     /locus_tag="VV588_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU7083824.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(15240..15524)
                     /locus_tag="VV588_001502"
     CDS             complement(15240..15524)
                     /locus_tag="VV588_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7083825.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(15528..17558)
                     /locus_tag="VV588_001503"
     CDS             complement(15528..17558)
                     /locus_tag="VV588_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU7083826.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            17749..18756
                     /locus_tag="VV588_001504"
     CDS             17749..18756
                     /locus_tag="VV588_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU7083827.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            18759..18959
                     /locus_tag="VV588_001505"
     CDS             18759..18959
                     /locus_tag="VV588_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU7083828.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            19111..19293
                     /gene="rpmF"
                     /locus_tag="VV588_001506"
     CDS             19111..19293
                     /gene="rpmF"
                     /locus_tag="VV588_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU7083829.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            19309..19458
                     /gene="rpmG"
                     /locus_tag="VV588_001507"
     CDS             19309..19458
                     /gene="rpmG"
                     /locus_tag="VV588_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU7083830.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(19938..>20075)
                     /locus_tag="VV588_001508"
     CDS             complement(19938..>20075)
                     /locus_tag="VV588_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083831.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         6396 a         4306 c         3520 g         5853 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacataca tacggtaagg cgacgctgac gtggtttgaa
       61 gagattttcg aagagtatta atcactaatt atctatctca acaaatcttc ctagaatatg
      121 aacattttcc gagacagaga caaaggagct tggatccact tgtgtcataa tctgtttaaa
      181 ttcattaaac tctgcacgtg taatgacagt gattaaaact gcctttctct cgtgattata
      241 ggttccttct gcatcatgga tcatggttgc tccgcggtgc aattttttat ggattttttc
      301 aattaccttc tctggatgat ttgtcacaat catggcctgc atacgctttt gcttagtaaa
      361 gactgcgtct gtcacacggc tagagacaaa gatggtaatc atagaataaa gagcgtattt
      421 ccaaccaaag gtcaaacctg ctatcagcat gatagttcca tttaccaaga aagaaatact
      481 accaacattc ttacccgttt tcttgcgaat agtcaggctg acgatatccg tcccaccact
      541 ggagatattg tttcgaagag caaaaccaat ccccaaaccc ataacaacac ccccaaaaag
      601 ggcattgata atgggatcct ccgtcaaggt tgccacaggg acaaactgga taaagaagga
      661 actcatagat accgtgataa aggtaaagac ggtgaactta tggccaatct gataccaagc
      721 taagaccatc aaagggaagt taatggcgta gaagcttagc gaaatcggaa tatgaaaacc
      781 aaaccagtga ttactcaagg cagagataat ctgtgccaga cctgttgcac cactcgaata
      841 cacatgccct ggttggaaaa agaaattaac tgctactgct gataaaaaac catagaccag
      901 agaggccgaa atcttctcat catacttttc tcgagagata ctttgtaaga cacgtaaaat
      961 ttttatctga taagcaaagc ggcgcagata atagcgccac cgcttaattc gttttgcttg
     1021 tttcatcttc ttctacttgt aagctgagtt cctctagttg tttgagagcg actgttgatg
     1081 gagcttgtgt cattgggtca gttgccttgt tgttcttagg aaaggcaatg acttcacgga
     1141 tattttcttc tccagcaagc aacatgacaa aacggtcaag cccgatagcc aaaccaccgt
     1201 gtggtgggaa accatagtcc atggcttcaa gaaggaaacc aaactggtca ttggcttctt
     1261 cagctgagaa accaagagcc ttgaacatgc gttcttgaag gtctttttgg ttgatacgaa
     1321 ggctaccacc accaagctca taaccgttca agacgatatc gtaagcaatg gcacgaacct
     1381 tagccaaatc accttctaat tcgtgagcag tctcttcctg tggaagtgtg aatggatggt
     1441 gggcgctcat gtagcggcct tcttcttcag accattcaaa catcggccag tcaaccaccc
     1501 aaaggaagtt gaacttatca ttatcaatca agccaagctc tttagcaata cgtccacgaa
     1561 gggcacccag tgttgcatta gccacttcaa gcgtatccgc cacaaagaga accaagtcct
     1621 tatcttcaag agcaagcgct gttgtcaatt cttcttggat accagtcaag aacttggcaa
     1681 ctggtccgtt taattctcca tcaaccacct tgacccaagc aagacctttg gcaccatact
     1741 gtttggctac ttccgtcatc ttgtcgatgt ctttacgtga atagttgtcc gcagctcctt
     1801 tgaccacaat cgcttttaca gcaggtgctt ctgaaaagac tttaaagtct acacctttga
     1861 ccacttctgt caagtcctga agcaacatgt caaaacgagt atctggcttg tcagaaccgt
     1921 aaagagccat agcatcatcg tatttcatac gagggaacgg tagcgttact tcgatgcctt
     1981 ttgtttcctt catcacgcgc gcgatcaagc cttctgtaat atcttggatt tctttctcag
     2041 taaggaagga cgtttccaag tcgacctgag taaattcagg ctggcggtct ccacgcaagt
     2101 cctcgtcacg gaaacattta acgatttggt agtaacggtc aaaaccagca ttcatcaaga
     2161 gctgtttcgt gatttgtgga ctttgaggaa gagcgtaaaa atgcccctta ttaacacgag
     2221 acggcactaa ataatcacgc gccccttcag gcgttgactt agaaaggaat ggtgtctcca
     2281 cgtcgataaa ctccaactca tccaaatagt tgcggataga gtgggtcacc ttggcacgaa
     2341 gtttaagatt ttccaacatt tctggacgac gaaggtcaag gtaacggtaa cgcaaacgtg
     2401 tatcgtcatt tgcctcaatg ccatccttaa tctcaaatgg tgttgtctta gctgtgttaa
     2461 gcacaataag agctgtcacg tttaactcaa ccgcaccagt tggcaactta tcattggctt
     2521 gctcacgcgc agcgacctga ccagtcacct caataacaaa ttcgctacga aggctttcag
     2581 ctgttgccat aacctctgca gatacttttt cagggttgat aaccaactgc atgattcctt
     2641 cacggtcacg aagatcgata aagatcaaac caccaaggtc acgacgacgg ccaacccatc
     2701 ctttcaaggt tatttcttgt ccgatgtgtt cctcacgaac acgaccagca tacatactac
     2761 gtttcattat ttctctcctc ttttattctg ttactatttt accataaaag cgcaggctct
     2821 tcatgaaaat catcagaaaa gtttgccagt ctttaaaagt caggtgaaag ccctaaaaat
     2881 tagcgctaat actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtaggta
     2941 tggttactga ctccgtcagt tctatccaca acctcaaaac agtgttttga gcaacctgcg
     3001 gctagcttcc tagtttgctc tttgattttc attgagtata atacaaaaat ccgatgaact
     3061 tcaccggact cttttatttt gaatttttgc ctgctttacg cttttcagcg atttcggctg
     3121 cctttcgagg caagacaatt tccgttatgt aagccgtccc aaaacgcagt acacctgcaa
     3181 taggagcaaa gacaactgct agatagttat agaagaaatc gcctttgaag gcataagcta
     3241 gcgctccaat gatgaaaaat agaacgactg cctgaatcac tgctaataaa attactcgtt
     3301 tcatgtgacc tcctgactct attatagcat gagaatcatc aaaaagccga ctaaattatt
     3361 caaagcgtga agagaaatac tgtagaccag accttttctg ctaatgtaag ccaaacccaa
     3421 actaaaacca aggctaaaat agacaaaaaa ttgttgcaca tcacctggaa aatgaatcaa
     3481 ggcaaataga agactagata ccagaagaaa aatcagggtt cgtttactat tgtcctgctt
     3541 aggaaagaga tagcgtgcta acatccctct aaaaacaatc tcttccgtca aaggagcaaa
     3601 aataaccaca gcaaagaatg agaaaagtgg ttgagacaag gtcaagtctg tcgctatttg
     3661 ctgatttact gaaggatcat ctggcaagaa gaattgaacg accagagata agaaccaaac
     3721 caaggcagga agccaaataa atcggttaaa gccgctcttc tcaatataaa caggagcttt
     3781 ctgataccat ttgtaaatgc cgtacacata tactccagcc aagaccacat agagtagagt
     3841 aacagcatag ggtgaagcgc ctaaagcaag cgacgcagtc gcgagcccct gaataaagcc
     3901 atagataaag aaaaaggata gaagggctag aagaatccag ccaaggtttt taagtaattt
     3961 catagataac tcctttattt gaaataacgt tttaccatag gtaactgcat cacattgata
     4021 taaacatgga tggctcctac aagcaagaaa gctagtaact gaatctctcc tgtcaagaaa
     4081 gaaatgataa taagaaaaat atataaggct ggtaagacat attggtgtaa ttggaataaa
     4141 attcgaaaac tctgttccaa attagcctga cgctcccctt catcataaga atttatatag
     4201 ttcaagacat cctttggtgt agcgaaaaat tccaaatcaa actgacgaac aatcgcaatg
     4261 gttttaaaaa gagatttttg agcgactaag aataccacaa agagtaagaa agaaaggaaa
     4321 aatgtttgag ggtttgtatg caatataatc acctcactta atgaaataaa aatagccaat
     4381 ggaatcgcta cacctgtaat attaaaagca atggttccaa actcaagatt ccgatacatt
     4441 tgcacataat aggtttcatt cagatcgtca tccatttcct cttgatacaa ggaatgaaat
     4501 tttctgcttt tctttaagaa attgaaagtc aaaaacatac taatgaaacc tatcagtaaa
     4561 caaatagctg atatccatgg catcaaggct tttacatcta aaataatttc gtgggattcg
     4621 acacgtgcct taaacatccc tacaaacatg cccaagaacc cccccaagac aatagacatc
     4681 aaaaataaca atctacgttt ctttttcata ttcattctcc tttttcactt gctagatttt
     4741 tggatttctt ttcaatccat tcagttactg ggatgagagc aaagtagacc caaacaaatt
     4801 ggtcgctttg atagggatta aaccagctta ggtccatccc aatcagtaga aatacgctga
     4861 ctaataaagc tatgaccact acataataaa tcactttata cttgttcatc actcgtcctc
     4921 ctccaaacga aataccgatt cgactgtttc gttgaaaatt tgagatattt tcagggcaat
     4981 gataatggat ggggtgtact catcccgttc tagtaggcta atggtctgtc tggaaacccc
     5041 tgccagtttg gctaggtcgg tttgattgag accatcgcga gctcgaagct cttttagacg
     5101 attttttagt tgcatgttac acacctactc tccgtcaaat tcaacggttt ggatatcttc
     5161 aatacgttgc aacttgaatt tttctttccc ctttttatca acactacgta gtttgaccca
     5221 ttcctcgtca acatccacaa cttcccagtt atctggccca atatacactc ccgttataat
     5281 tggttccttt ccaatcattt cttgcaataa tctcgacatt tctgcgtttc ctttctcttt
     5341 tcgctcaagt tttttgattt tattctctag tttcttgatt tttttagaat tattagaata
     5401 aaagaaaatc ataaatagta taaatactag tacccacatt ataactcctt tctgcttcct
     5461 atttcttaac ttgaattcat tgtaacacat ctttttcttt ttgacaatta tagttgtcaa
     5521 aaagtttatg atttttgtca ttttgcaaaa gaaaaaggtc aggagtaagt tcctgaccac
     5581 tttatctatc attaatactc ttctaaaatc tcttcaaacc acgtcagctt caccttgccg
     5641 taggtatagt tactgacttc gtcagtttca tctacaacct caaaaccatg ttttgagctg
     5701 acttcgtcag ttctatccac aacctcaaaa cagtgttttg agcaacctgc ggctagcttc
     5761 ctagtttgct ctttgatttt cattgagtat aaaatcctag tttttcaaag atttctgaga
     5821 agttttggct gattgtctca agtgacactt gcacttcttc tcgggtttgg ttgttcttga
     5881 ccgtcacttg tccgctttcg acttcgctct ctcctagggt gatgagggtc ttagccgcaa
     5941 agacatctgc tgacttgaac tgagctttga gcttacggtt gaggtaatca cgctctgctt
     6001 tgaaaccttg ttggcgaaga gcttggacta gttctagggc tttgacattt gctccatcac
     6061 ccaagactgc gatatagaca tctagggcgt tttcgatagg gagggccacg ccttgttttt
     6121 caaggatgag aagcaggcgc tctacaccaa gcccaaaacc aaatccagca gtttcagggc
     6181 ctccaaagta agcaaccaaa ccatcgtagc gaccacccgc acagactgtc aagtcattgc
     6241 cctcaatctc tgtgataaac tcgaaaatgg tgtggttgta gtagtccaga ccacgcacca
     6301 tattggtatc gatgatgtaa tctactccaa gattttccaa catctgacgc acagcatcaa
     6361 aatgagtttg gctttcttca tcaagaaagt ccaagataga cggcgcattc tctactgcca
     6421 ccttgtcttc tttttcctta gagtccaaga cacgaagagg attttcctcc aagcgacgtt
     6481 ggctatcctt agacaaggtc tccttgagcg gtgtcaaata gtcaatcaag gcttggcggt
     6541 aggctgcacg gctctcagga tttccaagag tgttgaggtg caatttgaca ccttgaatac
     6601 cgatttcctt caaaaaatgg gctgccataa cgattgtttc cacatcggta gctggattgc
     6661 tagagccaaa acactcaaca ccaatctggt ggaattggcg caagcgccct gcctgtggac
     6721 gctcataacg gaacataggt cccatgtagt agaacttgct tggcttttgc acttctgggg
     6781 cgaagagttt attttccaca taggaacgga caacgggcgc agttccttct ggacggaggg
     6841 taatatggcg gtcacccttg tcatagaaat cgtacatttc cttggttacg atatccgttg
     6901 tatctccgac agagcggctg ataacctcgt aatgctcgaa aataggcgta cgcacttctg
     6961 cgtagttgta gcgcttgaaa atctcacggg caaagccctc aacgtactgc cacttagcag
     7021 actcagcagg taaaatatcc tgcgttcctt ttggtttttg taatttcata gggaatcctc
     7081 tttaaactta atagtcttat tttaccataa atagagggat taaaacagtg agaaaaaaat
     7141 taggatttag atatcatttt tgagattaag aattgtcaaa aaaatagcta gcaaggaaag
     7201 accaacaaat agcatccaag tcaactgtat attccatacg gctactagtg aaaaacaagc
     7261 tgttcccaca ggtatggata aggtaaacaa tagatctaaa aaattactag tacgagctag
     7321 aacctctgga gctagatttt tcatgagcat ggcactaatc tttggttgaa ctttaccaga
     7381 cacatacaga gtaaagaaga gaaatagcaa accaagcacg acttgattga ataaattagc
     7441 caaaccaact agactaagtc ctacagtcgc ccacatcatc aatctaggca aggactgctt
     7501 cccaaaataa gcattgcccg taaggctact gatgatgatt gctactaaaa cacagaattg
     7561 attgataaat agtgcctctg tataagaaaa attcaagaga gaatggctca aaaagaagat
     7621 attataaatt ccacccaaag cgccacccaa ggaattaata agcaagacag caaagagcat
     7681 aaaaccaaag tttttctgcc cacttttaag aaaaacgaga cgtaaatttc ggtaaattgt
     7741 taggaactgg tctttgatag aaagcttctc attttttaag ttttcaccat cagcagatga
     7801 cattgacagg ctcaatttgc tttttcctaa aaagaggata gtggctgata ctaggaaaaa
     7861 gcaggcattg attcccgcaa cgagagaaaa attgttgacc gatagagcta agagccagac
     7921 tccgaaagct tgaccaccaa tagctgaaat ataggtgatg aactgtgaaa aagaataagc
     7981 ctccatcaga tcatcttcag ctactttttc cttaataaga ggcatacgca ggccacctgc
     8041 aaaatcactg atgatatcac taatgacatt gatcaaacac aggctagaaa aggcaaagag
     8101 actagcttgc tgaacaacta gggctgctag aaaaaataga accgcctgaa acaaaccgct
     8161 atagaccatc catttgacct tgtccctcgt gtaatctgcc cgaatccctg caaaaactgt
     8221 aaagaaggtc ggaagaatca tgacaatatt cgccatagca acagcaaaag atgcttgtga
     8281 caaggtcgat gcatagacga taaagaccag gttgaaaatc gaagcaccaa aagcattgaa
     8341 gaagcgtgat aaagtcaaaa ttctataagc tggatttcta aacaatagtt tcatagataa
     8401 tctccctcct tgttctaagt tctacatcaa gaatagcttt agtatagcac ttatgaattt
     8461 gcgaaacgat tcttttgaat atatgcaaca aacaaaatga gcaaaaaaac gatagaactt
     8521 ttgtaatgac ctgagagagg gtaacagttc tatcgcttca aattttttct tggtttgcag
     8581 atactcaaca ttcggtcgta tttctatagt attcggcaga tttattacag ccaagcatct
     8641 caaaaatacg gacagcatcc tccatctttt tctggccttc cttgactcta ccttgcttgc
     8701 tatcaaggag accttctgcc cacagataaa caattcggaa ataggtctca ttttccttgt
     8761 agaaatgctc ttcgataaca cgtttaaaat aataggcatt ggtaaattct tcacactcaa
     8821 tactagctaa aaagccattc aatagtatag tatgaaaaag gtttcgattg ccagacattt
     8881 ccattagaaa atcagattta cgtaccattt ctcgtacata tctagtaaaa agagaaacag
     8941 ataaaaatgg agaactgact gaaaataaat tgagttcata gattccccag atctcggtag
     9001 aaaacaaata atcatgaagg acttttcctt cctctgctgt taactctacc ctttcatcta
     9061 tgctcttcat ataagacttg ataataatgg catttagaat atgtttctgt ttgttgtgag
     9121 aatgggcatg cttttgatac tccctgcgat ataagtcctc aagaggtgct atattctttg
     9181 gttccaagac atctgtaatt tcttttctca actcagaatc tgtatcatac tggaaacctc
     9241 tcgccagaaa gaggatctcc tccacactgg cagatatatt ttccagagca aatagaaact
     9301 tttccaccaa aagctcactc tgacctgttt caaaacggga caacatagac ggcgaaaatt
     9361 gtcctccggt tgcttgtctc agtgagatat ttcttgactc tcgtaattgt ctaaagactt
     9421 ttccaatctg ctccatagac ttccccttga ttccgtattt tcttcatttt atcatatttt
     9481 tcagaaaatt catcaaaaac ttgccaaatt gtcagaatta tgagaaaata gaggatattt
     9541 atcacgtgga gggactgcta tgagagacga tatcaaaatc aatgaccgtg ctttggcctt
     9601 gcaagaccaa attatcgaaa aactagagaa agtttttgat acagatgtgg aattggatgt
     9661 ttacaatcta ggtctgattt atgaaatcaa tctggatgaa acggggctct gcaagattgt
     9721 catgaccttc accgatactg cctgtgattg cgccgaaagc ctgcctattg aaatcgtggc
     9781 aggtctgaaa caaatcgagg gtatcgaaga tatcaaggtt gaagttacct ggtcgcctgc
     9841 ttggaaaatc acacgaatca gtcgctatgg ccgtattgcc cttggactac cacctcgtta
     9901 agcaggccaa tcacttttaa agatgaaaaa agcaagccga aaatggcttg ctttttgata
     9961 ctcaatgaaa atcaaagggc aaactagaaa actagccgca ggttgctcaa aacactgttt
    10021 tgaagttatg gatagaactg acgaagtcag ctcaaaatac tgttttgagg ttgtggatag
    10081 aactgacgaa gtcagtaacc atacctacgg caaggcgacg ttgacgtgat ttgaagagat
    10141 tttcgagtat gagtttattt tttacctgac ttgtccatat tccagaagtc tgtcacggct
    10201 ccgcgtgaag cagatgatac gatgtgggca tatttaccga ggacaccacg gctgtaaagt
    10261 ggtggcaagg ttgtttctgc cttgcgtttt tcaagttctt cttcggatac ggccatggaa
    10321 atttctttgg tatcttggtc aaccgtaacg atatcgccgg tacggagata ggcaattggt
    10381 ccaccatcct gagcttcagg agcgatatgt ccaacaacca gaccataagt accaccagag
    10441 aaacgtccgt ccgtcaagag ggccacctta tctccctgac ctttaccaac aatcattgaa
    10501 gaaagtgaca gcatctcagg cataccagga ccacctttag gtccaacaaa acgaacaacg
    10561 actacatcgc catcaatgat ttcatctgtc aggacggcct gaatcgcatc ttcttctgag
    10621 tcaaagacct tagctggccc aacgtgacga cgcactttaa cacctgatac cttggcaact
    10681 gcaccgtcag gagcaaggtt cccgttcaag atgataagcg gaccatccgc acgttttgga
    10741 ttttcaagtg gcatgataac tttttggcct ggagtcaagt ctgcaaagtc agccaagttt
    10801 tcagctacag tcttaccagt acatgtgatg cgatctccgt gaaggaaacc atttgccaac
    10861 aagtacttca taaccgcagg gacaccaccg acttcgtaga ggtcttggaa gacatactga
    10921 ccagatggtt tcaagtcggc caagtgaggc acacgttctt gaatcgtatt gaagtcctca
    10981 agtgacaagt caacatttgc ggcatgggca atggcgagca agtgaagagt ggcgtttgta
    11041 gaaccaccga gagccatcgt tacagtaata gcatcttcaa aggcttcacg agtcaagata
    11101 tctgatggtt tgagaccaag ttccaacatc ttaacaacag cacgtcctgc tgcttcgata
    11161 tcttctttct tatcagctga ttcagctggg tgagaggatg accctggcaa actcatccct
    11221 agaacttcga tagcagttgc catggtatta gcagtataca taccaccaca accaccaggg
    11281 ccagggcagg cattacattc aagacgtttc acgtcctcag ctgtcatgtc accgtggttc
    11341 cattttccga taccttcaaa gacagaaacc aagtcgatat ctttaccatc aagatttccc
    11401 ggtgcaatag ttccaccata ggcgaaaata gctgggatat ccatattagc aatagcaatc
    11461 atagatccag gcatgttctt gtcacagcca ccgatagcga cgaaggcatc cacgttgtga
    11521 ccactcatag ccgcctcgat ggagtccgcg atgatgtcac gagatgttag agagaaacgc
    11581 ataccaggcg ttcccatagc gatcccgtcc gctacggtaa tggttccaaa ctgtacaggc
    11641 caagcgcctg cagatttgac accttcttta gccagtttcc cgaaatcatg caagtgaatg
    11701 ttacatggtg tattttccgc ccaagtcgaa atcactccca caatcgatgt ttcaaagtcc
    11761 ttatctgtca taccagtcgc acgaagcata gcacggttag gtgatttaac catgctgtca
    11821 taaatgctac tgcggtgacg tttatctaat tcagtcatct tatccctccc atttcagttt
    11881 ttactattat agcacaattt aaaggcaatg aacagaataa aattcttgaa ttttcagaaa
    11941 attctatacg catgtgaaat atttaaaatt aaaaacaaca aagcggatta gtgcactttc
    12001 tgatgaccag aatatgcttt ttaatccgct ttctttaaat aacgtactgt aatttttaca
    12061 gaaattcttt cagataagtg tatttaacat ctatcttgca ttataaattt ctagaacctt
    12121 ctcttttata ttcgattcac tcaaaccata ctcattaaga agataatcca ttttccctac
    12181 ttgaccgaat ctttcttgaa cacccatccg atgaattttt gttattccat catcagagaa
    12241 taattcacat aaagcactgc caattccacc tatctgattg tggttttcta cagtaaatat
    12301 agtttttcca cttaacattg tttttatctg ttctggtatc ggtttgattc taaataaatc
    12361 tatcacacct actgaataac ctaatttaga cagttcatct gcaactcgaa tacttggagc
    12421 aaccattatg ccagaagcaa cgattacaag atcttcacca tgtcttaact caatgtagcc
    12481 cttagaaaaa tcttctccac cttgatatac agcctctgga gcttttctaa ttgttcgaat
    12541 atattttagt ccttttaagt ctaatgtctg attcaatatt tcacgaaatt ggatatcatc
    12601 agttgcttca aaaatgattg atttaggaat taaacgtaac aatccaattt cttcaaatgg
    12661 catatgtgtc ccaccattca tttctgcagt tactcctgca tctgatccaa tcacagtggc
    12721 atccaattgt gcgtatccaa gagaaataaa taattgatca aatactcttc gtgaagcaaa
    12781 aggaccaaat gtatgaagat aaggtctaaa cccctgaata gacaagcctg ctgcaaggcc
    12841 gaccatttct gcttccataa tcccaacatt cacataacgg tctccaaagt tcttttcaag
    12901 attattagta gccatcgaac ttgacaaatc ggcttctaag actactatat cagaataact
    12961 ttgattagcc tctaaaagga agtctctata tacatgccgt aattctttcg tacttctcat
    13021 cattctgttt cctccaattc ctgacttaat ctttctacaa ctgaagttaa catttgtttc
    13081 tcctctacag tagggcgaag atgatgattg gatttcattt cttccagctc ttgaacccct
    13141 tgacctttaa tagtatctaa tacaatgcac ttaggtgatg aattatttga ctgttttaat
    13201 tggacaatcc cttcataaat ttctctaata tctgaaccct tgaccctaat ggattcaaat
    13261 ccaaatgctg aaaatttttc tacgaaatca cctggattac aaatatcctt tgtaaaacca
    13321 tctaattgtt ttttgttatc atcaacaaat acaattaagt tggataactg ttgatgagaa
    13381 gcaaactgta tagcctccca acattgtccc tcatttaact caccatctcc aacaatagca
    13441 taagtataaa agggactctt tcttattctc tgaccatatg caagtccagt tgcaacacta
    13501 attccttgtc ctaaagagcc cgttgtcata tctatgcctg gcgttagatt tctatcagga
    13561 tgagacggta atttggttcc atttgtattt aaagaatata agaattcttt gtcaaagaaa
    13621 ccattcaaat agagtgtact gtatagagct ggtcctccat gaccttttga taatatgaaa
    13681 taatctctat ctcgtgctgc aaatatttct ggagtcattg gcattatttc accataaagc
    13741 actgctaaaa cttctacgat agacagactt cctccgtaat gtccgaatcc aagatgattc
    13801 aatgttctaa gagtatttaa tcggatgtta gtcgcaaatt ttcttaaccc atcttctcta
    13861 tttttactta aaatcatccc ttattcctcc tttgcagatg gctttttaat aaaggatact
    13921 ccaaacataa ctgctagaat aagaacaaga ccaatcacaa tacctgcttg tgagccaaat
    13981 tgatttaaca ttcctaaaat aattcctgat agaccaaaat ctgcatctga gaaagttgat
    14041 ccttggaaac caagtcctcc caaaactggc attaaaaaga ctggaagaaa actgattaaa
    14101 ataccttgta aaaatgctcc aatagtggcg ccacgaacac caccagatgc attcccaatg
    14161 acacctgcag tcgctccaca gaagaaatga ggcacaacac ctggtaagat aacaaccgtt
    14221 cctgaagcaa tcataattgc catacttact aaaccaccaa caaaactaga gataaatcca
    14281 attagaactg cattgggtgc ataagtataa acaatcggac aatccaaagc aggttttgaa
    14341 ttaggtacaa gacgctctga aataccttta aaggctggaa caatttcgcc caaaataagg
    14401 cgaacacctg ctaaaataac aaatacccct gctgcaaatt gacctgctaa ttgtaaagca
    14461 taaactagac cacttgtacc actactgatt tctttttcta tatattctga ccctgcaaag
    14521 atagctacaa taatgtaaat aactgccata gataaagtga tactaacagt actatcacgt
    14581 aaaaaagcta aactctttgg aaatttaatg tcctctgttg attttgattt gtcaccgata
    14641 aggctaccag taaaaccact caaccaatat cccaaagaac tgaaatgacc taaagccacc
    14701 ttgtcatttc cagttaattg aaccatatat ttttgcacaa atgctgggga aatactcata
    14761 ataataccga gtgctaatcc tcctagtaag atgagaggca agctagtaaa gccagcaact
    14821 gataaaatga ccgcaatcat acatgccata tatagagtgt ggtgccctgt taaaaaaata
    14881 tatttaaatc gagtaaaacg agcgattaag atattgaaca ccatgcctgc aaacataatc
    14941 attgcagtag ctgagccata tgttgttaaa gctacagcta caattgcttc attattcggc
    15001 acaacgccag ataaatgaaa agcatgctca aacatggtac caaatggatt taaagaattt
    15061 tgtacaattc ctgcaccacc agatacaact aagaaaccaa caaaggtctt aattccacct
    15121 ttaataatat caggtaattt cttcttctga agaactaatc ctaaaattgc aattaaagct
    15181 actaaaatag ctggtgtact aacaatatcc aatatgaact tcatcatgac gctagcctcc
    15241 tatataagtc ctttttcttc acaaagttta gtaattaatt ctcgtagttc atccatatca
    15301 ataatactat ttaagatacg aacatctcca agatgactag ctgaatcagc tagatcacga
    15361 ccaacaatcc aaatatcagc tgcatttgga tctgctccac ctaaatcata atgttcaact
    15421 tctacatccg aaacattcaa atcactcaat acagattcaa tattcatctg taccataaaa
    15481 cttgaaccta atcctgaacc acaagctgta ccaattttta acattatcta atcctcctgt
    15541 ttaattatca ttttaatgtc atcatagttt tttgatgata ttaaagtttg aacatgattt
    15601 ttatctctta aaattgttgt taaatgtgac aaagccttta aatgactctc attatcaatg
    15661 gctgcaatac aaatcaacaa tcttacctct tgttctggat tatccaataa ataaatcggt
    15721 tcttccaaaa ctaacattga cattcctatt tcattcacac cttcatctgg ccgagcgtga
    15781 ggaattgcta ctcccttccc taaattaata aaaggtccaa actcttctac tttttgaatc
    15841 attgcctcag ggtagttctc agttatctta tcttgatcca aaagcggttt agctgctaaa
    15901 cgaatcgcct ccttccatcc taatttttgc gaactaacct gataggtttc tttggtaata
    15961 agttgttcta gcactggtac aatttccttt ctatcatttt tttggtaaag ataattcttt
    16021 aacgccaatc ttaattccaa ttcttgtgta ataattccat atcttttgac aatattcagg
    16081 atttgttcaa tctcaaaatc tccatactct aaattcggaa aatcttttaa cactagttct
    16141 actagttgta ttgcttgctc ttcagtcatc ataaccgaaa ctagataatt tggcttttct
    16201 gtctccacct ttatggtaga aaaaaccata tcatagtcac tactagcttt cacctgtaaa
    16261 tcatcaatct ttgaggttcc tataaactca atttgaggaa ataatgctaa tagattctct
    16321 tttaacatca atgaagaact aacaccatta ggacaaatga ttgctgcttt atagcatttt
    16381 tgaggcaaag tatctgcttt ctttaaataa cctccgaaat ggataacaaa atatgctgtt
    16441 tcactatcag gtatgggatt gtcaatagcg tccatcaagg gcatcaaaga atctttgact
    16501 aattcaaata aatcaggata atgttcttta acatgcaata catattcatt tgaactaggt
    16561 aggccgaact ttaatctata gtaagccggt ataaggtggc ggcgaagatt ttctctcaat
    16621 ccttcccttt gtttaaaatg taacaaagaa atatcttcca ttctacttat aatagcctct
    16681 gttaattgat taaagtaaac cggagcaaca tctacttcac cttcaaagca acttgataat
    16741 aaaactgtga tatagcgata atcatcctca gaaaacaccg tatctataat tcccaaatca
    16801 accactgtat ccaataaaat agtggttata tcttgaataa caggagatac taatgtctct
    16861 gaaagacata ctctttcaac atccctttga tacctacaca gaatgaatac taaaccgaaa
    16921 aggcaaactt ttaattgatt aacaataggt actagttgta gcttctcata ataatcttta
    16981 actacctgat ttatcaaatc ataagttaat gaataccccc aactggataa aacataatcc
    17041 aaaccccaaa tccctatgga ggattccagc aactcactaa ccatttgaaa agctaagcgg
    17101 tgcttattcc actctgaacc gtgtaaagta taaccttttg ctctactgta ccctagctcc
    17161 aaatcattat ctaacataat ctttcttaat gattgaatat cagataaggt tgtattctta
    17221 cttactttca aaaagtcttg gtaatgatta ttcgatataa aatctaatcg gcaaaaagtg
    17281 taaagataga ttaaagctaa gcgagtcgac tttggtaaaa ccaattcatc cgacttaata
    17341 atatctgtca aagactgctt cgtacgattt gataaactat agcgaccttg ttttttatcc
    17401 agcactatcc ctttattagc tagataaggc actaaataat ctattccttc tttgacttcc
    17461 tttataggta agctcacctt aacagataat tcatataatg atagctcaca atgatccatc
    17521 aaagtcatca aaataactag tgctctataa tcaaacattt ctcttccttt ctaactacaa
    17581 ttatagtgta aaaattataa gaataaaaga gtatttgagc acaatataat ctcacctttt
    17641 aaaagaaatt attgggctga aagtttttag tgattatttt caactttcta ttgactttta
    17701 aaaacaaagt gatatcattt agatatcaaa taatgggagg tcattcttat gactgaaaaa
    17761 ctaatcaatt caaaaccaaa tggtgtattc gcattgattc tcattgagtt gacaatcgta
    17821 cttggtgtct ttatatttat aatgggtgtt ggttcggaaa acatttttgg aattattatc
    17881 ggacctttac taatcgtaat tgcaggtcta gctcatgctg gtttaaaagt tgtcaaacct
    17941 caggaagctc tggttctgac actctttggt aattatacag gtaccatcaa agaacctggt
    18001 ttttactttg tcaatccctt cagcgtagca gtcaaccctg caaaccacac tcgacttgga
    18061 caaagtggtg atgttagcac aaaatctcct tttttaggag ctaaatcatc aaatgacaat
    18121 gatgtaaatc ttgaaattgg caagaaacac atttccctca aagtcatgac cttgagcaat
    18181 tctcgtcaaa aaatcaatga ttgcttagga aaccctgtag aaatcggtat cgcggtaact
    18241 tggagagttg tcgataccgc taaggcagtc ttcaacgttg ataactacaa agaatatctt
    18301 tcactgcaat gtgatagcgc cctccgtaat attgtccgca tctatcctta cgatgtgtct
    18361 cctaatgtgg atactacggg tgacgggcaa gcagatgaag gtagtctccg tggctctagc
    18421 gaaattgttg ctaaccgtat tcgtgaagaa atccaaagtc gtgttgagga tgctggcttg
    18481 gaaatccttg aagcacgtat cacttaccta gcttatgctc cagaaattgc tgccgttatg
    18541 cttcaacgcc aacaagcatc tgccattatt gatgcacgta agatgattgt agatggtgct
    18601 gtaggaatgg ttgaaatggc actagaacgg ctcaatgaag gggaattggt agaacttgac
    18661 gaagaacgaa aagctgccat ggtttcaaat ctccttgtcg ttctttgtgg caatcatgat
    18721 gcacaaccaa ttgtcaacac aggaagtctt tactaaagat ggctgaagct aaaaaaaagc
    18781 agatccccct tcgactctca acaaagttat acgctgcact cgcatcatgg gcagaagacg
    18841 actttcgttc agtcaatggc caaatcgaat atctcctcac agagtgtgtc aagcaacgga
    18901 agaaagacgg aaaatacgta tcagaaacca ttgacgaacc atttgagatt gatatttaac
    18961 accttctcct gtctgccgtg tcggatagga gaattttttc atcttttttt gtcaagtaac
    19021 tttactttac aaaaaaaatg tgttatccta gtatggttga tgaaaatcag tagattgaat
    19081 cgaatataaa tacctaaagg agaaatcaaa atggcagtac ctgcacgtcg cacttcaaaa
    19141 gcgaagaaaa acaaacgtcg tacacactac aaagtaacag ctccatctgt aaactttgac
    19201 gaaactactg gagattactc acgttctcac cgtgtatcac ttaaaggata ctacaaagga
    19261 cgtaaaatcg ctaaagctgc atcagctgaa taatagaagg gagataccat gcgcgtaaat
    19321 attacacttg aacacaaaga atctggtgaa cgcttgtacc ttacttctaa aaacaaacgt
    19381 aacactccag accgccttca attgaagaaa tactcaccaa aacttcgcaa acacgttgtg
    19441 tttacagaag tgaagtaagc attcaatacg aatcaataca gaagaaaaac gcttgatcag
    19501 cgttttttct ttttgttaat ttcactatat tgcaagagaa atcattcgaa tgactacatt
    19561 ttttgaaata agaatacgga ttcggacgat taaaagtaag agaaactcaa atgtaagttg
    19621 gggttccttt tttgtatatt tttcaaataa cgcctctaca ctatttgtag caaattcacc
    19681 aactacagtt gcatcttagt taaaataagt tagaatatgt aagtgagtac cagatatacc
    19741 aagacatcgt caccatctaa ggtatattca aaatacaaaa gttgaccaac tagatttctg
    19801 aatatcctta tatatccatt cttaaaattg gtttaaatag cgtagtcttt taaactagtt
    19861 ttgagaatcc aaaaaatctt cctacatatg taagaagatt ttttagttca gaatgattag
    19921 atttagctaa tggataccta tcctacccac tcaccgttag cattgactcg atagccatcg
    19981 ggtgtagtcg tgtttactaa taaatctcct gaattatagg tatagtacca tttaccagaa
    20041 actgtaaacc aaccagtagc cattgaacct gattc
//
LOCUS       DAVIME010000038        19759 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVIME010000038 DAVIME010000000
VERSION     DAVIME010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.038"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            248..2176
                     /gene="glgB"
                     /locus_tag="VV588_001509"
     CDS             248..2176
                     /gene="glgB"
                     /locus_tag="VV588_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU7083832.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPNVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLICIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2166..3308
                     /locus_tag="VV588_001510"
     CDS             2166..3308
                     /locus_tag="VV588_001510"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU7083833.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3298..4437
                     /gene="glgD"
                     /locus_tag="VV588_001511"
     CDS             3298..4437
                     /gene="glgD"
                     /locus_tag="VV588_001511"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU7083834.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4434..5867
                     /gene="glgA"
                     /locus_tag="VV588_001512"
     CDS             4434..5867
                     /gene="glgA"
                     /locus_tag="VV588_001512"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU7083835.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHIHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWLAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5926..6297
                     /locus_tag="VV588_001513"
     CDS             5926..6297
                     /locus_tag="VV588_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU7083836.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6242..6571
                     /locus_tag="VV588_001514"
     CDS             6242..6571
                     /locus_tag="VV588_001514"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU7083837.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            6580..7695
                     /locus_tag="VV588_001515"
     CDS             6580..7695
                     /locus_tag="VV588_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU7083838.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7692..8138)
                     /locus_tag="VV588_001516"
     CDS             complement(7692..8138)
                     /locus_tag="VV588_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU7083839.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8302..9606
                     /gene="eno"
                     /locus_tag="VV588_001517"
     CDS             8302..9606
                     /gene="eno"
                     /locus_tag="VV588_001517"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU7083840.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9744..10124)
                     /locus_tag="VV588_001518"
     CDS             complement(9744..10124)
                     /locus_tag="VV588_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU7083841.1"
                     /translation="MRLFCLVLVSIDYINCLSETTDKNWHKSDRVFVTNTGKTVHSSI
                     LSKSLQRANERLKKPIPKHLSPHIFRHTTISILSENKIPLKTITDRVGHSDSEVTTSI
                     YTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(10090..10936)
                     /locus_tag="VV588_001519"
                     /pseudo
     CDS             complement(10090..10936)
                     /locus_tag="VV588_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            11004..11159
                     /locus_tag="VV588_001520"
                     /pseudo
     CDS             11004..11159
                     /locus_tag="VV588_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            11359..14634
                     /gene="rexB"
                     /locus_tag="VV588_001521"
     CDS             11359..14634
                     /gene="rexB"
                     /locus_tag="VV588_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU7083842.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYCFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            14631..18281
                     /gene="addA"
                     /locus_tag="VV588_001522"
     CDS             14631..18281
                     /gene="addA"
                     /locus_tag="VV588_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU7083843.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEVYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYIFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLTSLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            18451..19629
                     /locus_tag="VV588_001523"
     CDS             18451..19629
                     /locus_tag="VV588_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083844.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFYRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERDIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         5997 a         3783 c         4261 g         5718 t
ORIGIN      
        1 agacattgtt agaaattaga ttaaagtcct taatcgattt gcgcatgttt tatttcattt
       61 cactatagta gaaaaagaaa ggcgttttcg caattttttg aaaaaatatt gatttacaat
      121 tgaacgagta agtgaacttg ttgtagattt tcaaaataat taaagaagta tagtaattta
      181 cttgaatctt ctctaaaaag gtagtataat aaaaacatag aaaacgctta caggagaagg
      241 ggagtatatg gataatagag aagcattaaa aacctttatg acgggtgaaa atttttatct
      301 ccaacattat ctaggagcac atagggaaga actaaatgga gagcatggct ataccttccg
      361 tgtttgggca cctaatgctc aggctgttca cttggttggt gattttacca actggattga
      421 aaatcagatt ccaatggtaa gaaatgattt tggggtctgg gaagtcttta ccaatatggc
      481 tcaagaaggg catatttaca aatatcatgt cacacgtcaa aatggtcatc aactgatgaa
      541 gattgaccct tttgctgtca ggtatgaggc tcgtccagga acaggggcaa tcttaacaga
      601 gcttcctgag aagaaatgga aggatggact ttggctggca cgaagaaaac gttggggctt
      661 tgaagagcgt cctgtcaata tttatgaagt tcacgctgga tcatggaaaa gaaattctga
      721 tggcagtcct tatagttttg cccagctcaa ggatgaactc attccttatc tcgttgaaat
      781 gaactatact catattgagt ttatgccctt gatgtcccat cctttgggct tgagttgggg
      841 gtatcagctt atgggttact tcgctttaga gcatgcttat ggccgaccag aggagtttca
      901 agattttgtc gaggagtgtc atacccataa tattggggtt attgtggact gggtaccagg
      961 tcactttacc atcaacgatg atgccttagc ctattatgat gggacaccga cttttgaata
     1021 ccaagaccat aataaggctc ataaccatgg ttggggtgcc cttaattttg accttggaaa
     1081 aaatgaagtc cagtccttct taatttcttg cattaagcat tggattgatg tctatcattt
     1141 ggatggtatt cgtgtggatg ctgttagcaa catgctctat ttggactatg atgatgctcc
     1201 atggacacct aataaagatg gcggaaatct caactatgaa ggttattatt tccttcagcg
     1261 cttgaatgag gttattaagt tagaatatcc aaatgtgatg atgattgcag aagaaagttc
     1321 gtctgcgacc aagattacgg gaatgaaaga gattggtggt ctaggatttg actacaaatg
     1381 gaacatgggc tggatgaatg atatcctccg tttctacgaa gaagatccga tctatcgtaa
     1441 atatgacttt aacctggtga ctttcagctt tatgtatgtt ttcaaggaga attatctctt
     1501 gccattctcg cacgatgaag tggttcatgg caagaagagt atgatgcata agatgtgggg
     1561 agatcgttac aatcaattcg caggcttgcg caatctctat acgtaccaaa tttgtcaccc
     1621 tggtaagaaa ttgctcttca tgggtagcga atacggtcaa ttcctagaat ggaaatctga
     1681 agaacagttg gaatggtcta acctagaaga cccaatgaat gctaagatga agtatttcac
     1741 ttctcagcta aaccagtttt acaaagatca tcgctgtctg tgggaaatcg ataccagcta
     1801 tgatggtatt gaaatcattg atgcggataa tcgagaccag agtgttcttt cctttattcg
     1861 taagggtaaa aagggagaaa tgttaatctg tatctttaac atggtacctg ttgagcggaa
     1921 agattttaca atcggactac ccgttgcagg aatttacgaa gaagtatgga atactgagtt
     1981 ggaagagtgg ggaggcgttt ggaaagaaca taatcaaact gttcaaacgc aagaaggact
     2041 atggaaagat tatgagcaga ccttaacctt tactctaccg gctatgggag caagtgtatg
     2101 gaaaatcaaa cgtcgcttga aatctactaa aaccgtcaca aataaaaacc aaaaaggagt
     2161 agaaaatgaa aaatgaaatg ttagctttga ttcttgctgg tgggcaagga actcgtctcg
     2221 gtaaactcac tcaaagcatc gcaaaaccag ctgtgcaatt tggtgggcgc taccgtatca
     2281 ttgactttgc cctatcaaac tgtgccaact cagggattca taatgttggg gtcgttacac
     2341 agtatcaacc acttgctctc aacaaccata ttgggaatgg ttcaagctgg ggactagacg
     2401 gtatcaattc aggtgtctct attcttcaac cttattctgc aagtgaagga aatcgttggt
     2461 ttgaggggac tagtcacgct atttaccaaa atatcgacta tatcgacagt gtcaatcctg
     2521 agtatgtctt gattttgtct ggggatcaca tctacaaaat ggactatgat gatatgctcc
     2581 agtctcataa ggataataat gccagcttga cagtagcagt tttagacgtc cctcttaaag
     2641 aagcaagccg ttttggtatc atgaacacag atgctaacaa tcgtattgtt gaatttgaag
     2701 aaaaaccagc tcaacctaaa tctacaaaag cttctatggg aatctacatt tttgattggc
     2761 aacgccttcg taatatgtta gtcgctgctg aaaagagcaa ggttggcatg tcagactttg
     2821 ggaaaaatgt cattccaaat taccttgagt caggtgaaag tgtttatgct tacgaattta
     2881 gtggttattg gaaagatgtt ggtactattg agtcactttg ggaagcgaac atggagtata
     2941 tttctccaga aaatgccttg gatagtcgta accgtcaatg gaagatttac tcaagaaact
     3001 tgatttcacc accaaacttc ctcggggcaa atgctcatgt ggaagactca ttagttgtag
     3061 acggatgttt cgttgatgga actgttaaac attctatcct ttcaacaggc gcgcaagttc
     3121 gcgaaggagc ggaagtcctt gattcagtta tcatgagtgg agctatcatt ggtcaaggag
     3181 ctaagattaa acgtgccatt attggtgaag gtgcgattat ttctgacggt gtcgaaattg
     3241 atggaacaga tgaagtacaa gttgtaggat ataatgaagt agtgggggta gcaacagatg
     3301 aagattgata aatattctgc cattttagga aatacagttg gttttcacaa tatgtcgaca
     3361 ttgacggacc accgtccagt agcaagtttg ccatttggtg ggaaatatcg tttgattgac
     3421 ttcccacttt caagccttgc taatgcaggt gttcgtagtg tctttggtat tttccagcag
     3481 gataatatca gctcagtatt tgaccatatt cgttcaggac gcgagtgggg cttatcaacc
     3541 cttcttagtc attactatct aggaatttac aatacccgtg tagaaagtag tacagttgga
     3601 aaagaatact accaacagct tcttacttat ttgaaacgtt ctggctcaaa ccaaacggtt
     3661 gccctcaact gcgatgttct tattaacatt gatttgaacc aagttttcca cctacatagt
     3721 acaacaaaag agcctatcac tgtagtttat aaaaaactag ctaagaaaga tatttcagaa
     3781 gtaaatgcaa tcttggatgt agatgaaaca gaccatgttc tttctcataa actctttgat
     3841 agcaagtcaa cagctgaaac gttcaatatg tctacagata tctttgtcgt tgatacacct
     3901 tggttgattg aacacttgga agaagaagct aaaaaagaac atccaaagaa attgcgctat
     3961 gttttacggg atttggctgt aaaagaggga gctttcgcct acgagtacac gggctatcta
     4021 gccaatattc actctgttaa atcttattat caagcgaata tcgatatgct tgaatcacaa
     4081 aaattctatt ctcttttctc accaaaccaa aagatttata caaaggtcaa aaacgaagag
     4141 ccaacttact atgctaatac atctaaggta agcacttctc agtttgcctc tggtagtatt
     4201 attgaaggtc aagtagctaa ttctgttcta tcacgtaata ttcatgtcca taaggatagc
     4261 ttggttaaag atagcctgct cttccctcgt gttgttattg gagaaggggc tcaggtcgaa
     4321 tatgctatct tggacaaagg ggttgaagtt gagcctggtg ttgtgattcg aggaactgca
     4381 gaacatccag ttgtggttaa gaaaggtgct aaagtaacag aggatattca ttcatgaaaa
     4441 ttttatttgt agcagcagag ggtgcaccct tttcaaaaac aggtggtttg ggagacgtca
     4501 ttggcgctct tccaaaatca ctggtaaaag ctgggcacga agttgcagtg attttaccct
     4561 actatgatat ggtagaggct aaatttggaa atcagattga agatgtgctt cattttgagg
     4621 tgagcgttgg ttggcgcaga cagtattgtg gaattaagaa aacagtatta aatggtgtaa
     4681 ccttctactt tattgacaat caatattatt tcttccgtgg tcatgtttac ggtgattttg
     4741 atgacggaga acgctttgcc tttttccaac tggctgccat tgaggctatg gaaaggattg
     4801 actttattcc tgatcttctc catattcatg actaccatac agctatgatt cctttcttgt
     4861 tgaaggaaaa ataccgttgg attcaagcct atgaggacat tgaaacagtt ttaaccattc
     4921 ataatttaga attccaagga caattttcag aaggaatgtt gggtgatttg tttggagttg
     4981 gccttgaacg ttacgctgat ggcacccttc gatggaacaa ctgtctgaac tggatgaagg
     5041 caggtattct ctatgcgaac cgtgtttcaa ccgtttcacc tagctatgct catgaaatta
     5101 tgactagtca gtttggatgt aatttggatc agattcttaa aatggagtct ggtaaagtat
     5161 ctggtatcgt gaatgggatt gatgctgatc tttataatcc tcagacggat gctcttttag
     5221 actatcattt caatcaggaa gatttgtctg ggaaagccaa aaataaggca aaattgcaag
     5281 aaagagttgg cttgcctgtt agagcagacg ttccactggt gggaattgtt tctcgtttga
     5341 cacgtcaaaa aggttttgat gtggtggtcg aaagtcttca ccatatcttg caagaagatg
     5401 ttcagattgt tcttttggga actggcgatc cagcctttga aggagctttc tcatggttgg
     5461 ctcagattta cccagacaag ctatcaacaa atatcacttt tgatgtcaaa cttgctcagg
     5521 aaatctacgc tgcttgtgac ctcttcctca tgccaagtcg ttttgaaccg tgtggcttgt
     5581 ctcaaatgat ggctatgcgt tatggaacct tgccattggt ccatgaagtt ggaggcttgc
     5641 gagatacagt tcgcgctttc aatccaatcg aaggaagcgg tactggcttt agctttgaca
     5701 atctatctcc ttattggtta aattggactt tccaaacagc attggacttg tatagaaacc
     5761 atccagacat ttggagaaac ctacaaaaac aagctatgga gagtgacttc tcatgggata
     5821 cagcctgcaa gtcatacctt gacttgtacc atagtttagt taattaatag ataaaatcgt
     5881 atgatgactt catacgattt ttaggctgtt tagagaggag aactgatgtc tcaagtaaaa
     5941 ggcttgtgtg ttttggatgt agatggaacc ttaatcctag aagaagtgat tgatctttta
     6001 gggagagagg caggtcatga ggcggaaatt tcgcagatta caagtcgagc aatgcgagga
     6061 gagttggtct ttgaaagcag tttaagaaaa agagtgtcct tgttggaagg tcttcctatt
     6121 ttggtctttg ataacgtctt caactcaatt catctatcgc taaatgtccc agagttcatc
     6181 tctattctcc aaaagaatgg catcctagtt ggtctggtgt ctggtggatt tacaccaata
     6241 gttggagaga ttagcaaaat cccttggtat tgcctatttc actgccaacc agcttgaagt
     6301 caaagaaggt cttttaacag gaaaattagt tggacaaatt ataagtcccc aggtcaaaaa
     6361 agaaactctg gaaaaatgga gaaagaaact aaaactttct aaagaaagaa cggtggcaat
     6421 cggtgatggg gtcaataatc tattaatgtt gaagtcggcg gagttaggaa tcgccttttg
     6481 ttccaaagaa atgctcaaaa aagaaatacc acatcatgtt gacaagaggg attttttaga
     6541 agttcttcct ttgattgact gtttagaatg agggaaaata tgaagattgt aattgcaccg
     6601 gattcgttta aggaaagctt gacagctcaa caggtagctg aagcaataaa aagaggcttc
     6661 caacaatcga tagcagatgt agaatgtctc ctctgccctg ttggtgatgg gggagaaggt
     6721 actgtagatg ctatccgaca ttctcttgac ctaaaagaaa aatggatcca agtgacagac
     6781 ccttttggac aaaaagaagc catgcgctat tttcaaaaag gggaactggc actatttgaa
     6841 gtagctgact tggttggtct tggaaaaatt ccgctagaga aacgaaatcc acttcaaatc
     6901 caaacttgtg gtattggaga gttgattctc catctcattt ctaaagggat taaagatatt
     6961 tatatcggtg ttggtggcac ggccagtaat gatggaggac tggggattgc tgctggttta
     7021 ggttatcaat tttatgatag ggatggaaat gtcttgcctg cttccgatca atccttatta
     7081 aacttagctt ctgtttcaac agaaaattgc tataaaattc ctgaaggtgt tcaaattcat
     7141 attctagcag atgtcgtgag tcccttatgt ggtcatcaag gtgcgactta cacttttggc
     7201 aatcaaaaag gtctacatcc gactatgttt gcagtcgtag atcaggcgat ccaagatttt
     7261 tatgaaaaat tctcacctgc aacattagaa attaaaggag caggagcagg tggaggcctt
     7321 gctggtggtt tgtgtgcctt tgctcaggca agtatcgtgt ctggaattga tacctgcttg
     7381 gacttaatca actttgataa gaaagtttca gatgctgact tggttgttgt tggagaagga
     7441 agacttgata gtcaaagctt tgctgggaaa gcgcctatag gtgttgcaaa aagaacccct
     7501 gttggagttc ctgttattgc tatttgcggt agtcttgctg aagatttacc tcccctacca
     7561 tttgaaaata tccaagctgt cttttctatt ttggagaaaa gtgaaccttt agaagatagt
     7621 ttgaaaaatg ccagtctcta tctggagcgc acggctgcca atattgggca cttattaaat
     7681 atgtgcaaga tttagctaaa ccatttcttc cataaggatg ttttggctgg ttcttccttt
     7741 ttaacttccc aaagttttgg aaaagcaagt cgaaggtctt tttcttctac ttgaactggt
     7801 gcattgctat gaataaccag gccaaaagga gaagtaatat gctcttcaga tactatggtg
     7861 gcttgactat cagtttcttt tgcttctttt aagtagaaaa cttgcttatc aaattcgata
     7921 gttggtgaaa tcttcacaaa tagtggctct gctttttcct gaaggttttc taaaataaat
     7981 aaaaagcctt tttctaactg agggctattt gctgtgtcaa tatctacata tccaagaact
     8041 ctttcctcaa aagtaccaag atagcgtctt tgttcatccg gatttatttt taacccacca
     8101 tgagcttttt caagtaattg ttttgataaa tctgtcatga aaacagtata tcataaaagt
     8161 tagaataaaa cagacaaaag aaagcgatta ctttataaag ttaaggaaaa gttgcacaaa
     8221 gataacgttt tttcttgaaa aaggaggggt tttaaggtat tatagaggtg taaaaaattt
     8281 aactcataag gagagtaaaa aatgtcaatt attactgatg tttacgctcg cgaagtccta
     8341 gactcacgcg gtaacccaac acttgaagta gaagtttaca ctgaatcagg tgctttcgga
     8401 cgtggtatgg ttccatcagg agcttctact ggtgaacacg aagcagttga acttcgcgac
     8461 ggtgacaaat ctcgttacgg tggtcttggt acacaaaaag ctgttgacaa cgtaaacaac
     8521 atcattgctg aagctatcat tggctacgat gtacgtgatc aacaagctat tgaccgtgct
     8581 atgatcgcac ttgacggtac tcctaacaaa ggtaaattgg gtgcgaatgc aatcctcggt
     8641 gtgtctatcg ctgtagctcg tgctgctgct gactaccttg aaatcccact ttacagctac
     8701 cttggtggat tcaacactaa agttcttcca actccaatga tgaacatcat caacggtggt
     8761 tctcactctg acgctccaat cgctttccaa gagttcatga tcttgccagt tggtgcgcca
     8821 acatttaaag aagcccttcg ttacggtgct gaaatcttcc acgctcttaa gaaaatcctt
     8881 aaatcacgtg gtttggaaac tgccgtaggt gacgaaggtg gattcgctcc tcgtttcgaa
     8941 ggaactgaag atggtgttga aactatcctt gctgcgattg aagctgctgg atatgtacca
     9001 ggtaaagacg tatttatcgg atttgactgt gcttcatcag aattctacga taaagaacgt
     9061 aaagtttacg actacactaa atttgaaggt gaaggtgctg ctgttcgtac atctgcagaa
     9121 caaatcgact accttgaaga attggttaac aaatacccaa tcatcactat tgaagatggt
     9181 atggatgaaa acgactggga tggttggaaa gctcttactg aacgtcttgg taagaaagta
     9241 caacttgttg gtgacgactt cttcgtaaca aacactgact accttgcacg tggtatccaa
     9301 gaaggtgctg ctaactcaat ccttatcaaa gttaaccaaa tcggtactct tactgaaact
     9361 tttgaagcta tcgaaatggc taaagaagct ggttacactg ctgttgtatc acaccgttca
     9421 ggtgaaactg aagattcaac aatcgctgat attgcagttg caactaacgc aggacaaatc
     9481 aagactggtt cactttcacg tacagaccgt atcgctaaat acaaccaatt gcttcgtatc
     9541 gaagaccaac ttggtgaagt agctgaatat cgtggattga aatcattcta caaccttaaa
     9601 aaataaaata gttcagtgaa ctattttatc ccgaaccatg aaattcaaaa gttcggccgt
     9661 tgatttaaca acgtttctag cccctcggat tttatccgaa gggctatttt tgtatttaga
     9721 ggacaaaaaa ggggcaaaac tttttaaaaa atctttttca taactttatc cagtacattg
     9781 attgcttcat ctttcatgtt ctttgtgacg tgggtgtaga tggaagtagt gacttcagag
     9841 tcggaatgac caaccctgtc cgtgattgtt tttaaaggaa ttttattttc tgataagatg
     9901 ctaatagtgg tgtgtctgaa gatgtgaggg gacagatgtt tgggaattgg ttttttaagg
     9961 cgttcgtttg ctcgctggag agacttgctc aagatagaac tatgaactgt ttttcctgta
    10021 ttggtaacaa aaacacggtc gcttttgtgc caattcttat cggttgtttc gcttagacaa
    10081 tttatatagt caattgaaac aagaacaaga caaaagagcc tcataaaagg tattgcaact
    10141 tggtaatacc tttttgaggt gctttttgat atgagcccat gttttctcaa taggattgta
    10201 ctcaggtgag tagggaggaa gaggtaaaag tttataccca aactcttcac acaagagttc
    10261 taacttaccc attctatgga atcttgcatt atccataata ataaccgatg gtgtggttaa
    10321 tgttggtaag aaaaacttct gaaaccaagc ttcaaaaaag tcgctcgtca tcgtctcttc
    10381 gtaagtcatt ggaacgatta actcaccatt tgttagacct gcaaccaaag aaatcctctg
    10441 atatcttctt ccagatactt tacctcttat taactgacct tttaatgagc gaccatattt
    10501 tcgataaaaa taagtatcga atcctgtttc gtcaatctaa acaggtgcta ggtgctttaa
    10561 actattaaaa ttcttaagaa ataaggctac tttttctggg tcttgttcat agtaggtgtg
    10621 gttctttttt tcgagtgtag cccatagctt tgagcgtata gtggatggta gttggatgac
    10681 agccaaattc agaagctatt tcagtcaaat aagcgtctgg attgtcagta agatagtttt
    10741 taagtctatc tctatcaact tttcttggtt ttgttccttt tacttggtgg tttagctctc
    10801 ctgttttctt ttttagcttt aaccagccat aaatggtatt acgtgagatt tggaaaacgt
    10861 gtgatgcttc tgttatacta cctgttcgct cacaataaga gagaactttt ttacgaaaat
    10921 ctattgaata tgccataaga agattatacc acattgtgtc ctatttttgg ttcattttac
    10981 tatagttcaa tcattctatc aagaatattg aatatataaa ggcacgtaat attaaaactt
    11041 cttctgatat cgaattagag tccgatgttg atggcgataa atcagacaat ctacccgtcg
    11101 acattaagac actgggacaa cacattgaag tgtattccgt acctaagaaa caatcataaa
    11161 actcaaagcc ttgttaccga ggctttttta ttatatgatt ttcagtggcc agacttattc
    11221 tatctaatac aagtaaagct aagtatttaa gatttagcag atgatgaaga aaagaaagga
    11281 tggcctaaat attttaacag atttacgagg ctaatcatgg tataatatag ggtgatgaaa
    11341 aattccaacg aggctgagat gaaattactt tatactgata ttcgaacttc tttgacagaa
    11401 attctaacaa gagaggcaga agagctagtt gcagctggca agcgggtctt ctacattgcc
    11461 cccaactctc tttcttttga aaaggaacgc gccgtgctgg aatgcttgtc ccagcaggct
    11521 tctttttcga ttaccgtcac gcgctttgct caaatggctc gttatctggt cttgaatgat
    11581 ttaccagtta aaactactct tgatgatatc ggtcttgggt tggcctttta caaatgcctt
    11641 gccgaactcg atcccaagga cttgcgtgtt tatggagcta ttaagcagga tcctcaattg
    11701 atccagcagt taattgagct ttaccatgag atgaccaaat ctcagatgaa ttttttggac
    11761 ttggagaatt taacagatga ggataagagg gcggatttac tcttgatttt tgagaaagta
    11821 acagcctatc ttaatcaagg tcagttagcc cagggaagtc agttgtccca tttgattgag
    11881 gctattgaga atgacaaggt aagtagtgat tttaatcaaa tcgccttggt cattgacggc
    11941 tttactcgtt tttctgctga ggaagagcgg gttgtggact tacttcacgg caaaggtgtt
    12001 gagattgtta tcggggctta tgctagtaag aaagcctata ccagtccttt tagcgagggc
    12061 aatctctacc aagccagcgt aaaatttctc catcatctgg cttctaaata ccaaacgccc
    12121 gctcaggact gttctcaaac tcatgagaag atggatagtt ttgacaaggc ctctcgtttg
    12181 ttggagtctt cttatgactt ttcagaactc gctttggatg tcgatgagaa agaccgtgaa
    12241 aatttacaaa tctggtcttg tttgacgcaa aaggaggagt tggagctagt agcccgtagc
    12301 attcgtcaga aattacatga gaactcagac ctgagctaca agcattttcg tattctcttg
    12361 ggggatgtag cttcttacca gttatctctc aaaaccattt ttgaccagta tcagattcct
    12421 ttttatcttg gtagaagcga agccatggct catcatccct tgactcagtt tgtcgagtct
    12481 attttagctt taaaacgtta ctgttttcgt caggaggatt tgattaatct tcttagaact
    12541 gacttgtata ctgacctcag tcagtctgat attgatgctt ttgagcaata tatccgctat
    12601 cttggtatca atggcttgcc agcctttcag caaatcttca ccaaatccca ccatggaaaa
    12661 tttaatcttg agcgtttgaa tgtcctccgc ctgagaattt tagcacctct tgaaaccctc
    12721 tttgccagcc gaaaacaaaa ggctgaaaac ctcctacaaa aatggagtgt ctttctaaaa
    12781 gaaggagctg tgaccaagca gttacaagat ttgacaacca ctttggaagc tgtagaacag
    12841 gaaagacaag ccgaagtttg gaaggctttc tgccatgttt tagaacaatt tgcgactgtt
    12901 tttgctggtt cacaggttag tctggaagac ttcctagcct tgctccattc tggaatgagt
    12961 ttgtcccaat accgtaccat tccagcaaca gtggacactg ttctggtgca gagttacgat
    13021 ttgattgcac cattgactgc tgactttgtc tatgctattg gactaactca ggacaattta
    13081 ccaaaaattt ctcaaaacac cagtcttctg acagatgaag aaaggcaaaa tctaaaccaa
    13141 gcgaccgaag aaggcgttca attactgatt gccagcagtg aaaatctcaa gaaaaatcgc
    13201 tacactatgc tttccttagt caattctgct cgtaagcagt tgttcttgtc ggctccaagc
    13261 ctttttaacg aaagtgaaag taaggaatct gcctatcttc aagagttgat ccattttgga
    13321 tttaggcgga gagagaagag gatgaatcac aaaggactgt ctaaggagga tatggggtcc
    13381 tatcacagtc ttttgtctag tctggttgcc tatcaccagc agggtgagat gagcgatact
    13441 gagcaagatt tgacttttgt caaggttctg tcgcgtgtca taggtaaaaa actagatcag
    13501 caaggtctgg aaaatccagc catcccaatc agtccaagca gcaagacctt agccaaggac
    13561 accttgcaag ctctctatcc tgccaaacag gagttttacc tgtctacgtc gggtttgaca
    13621 gagttttatc gcaatgaata cagttatttc ctacgctacg ttttaggctt gcaggaggaa
    13681 ttacgtttgc gtcctgatgc ccgtagtcac gggaatttct tgcatcgtat ctttgaacgc
    13741 gccttgcagt tgcctaatga agattccttt gaccaacgtc tagaacaagc tattcaagaa
    13801 accagtcaag aacgcgaatt tgaagctatt tatcaagaaa gtttggaagc ccagtttacc
    13861 aaggaagttt tgcttgatgt tgcacggaca actggacata ttctccgaca caatccagcc
    13921 atcgaaacaa tcaaagaaga agcaaatttt ggtggaaaag accaagcctt tattcaatta
    13981 gacaatggac gcagtgtctt tgtacgaggc aaggtggacc ggattgaccg tttgaaagct
    14041 aatggagcga taggagtagt agactacaaa tccagtctga ctcagttcca gtttcctcat
    14101 ttctttaatg ggctcaattc tcagttacca acctatcttg ctgccctaaa aagagaaggg
    14161 gagcagaact ttttcggcgc catgtacttg gaaatggctg aacctgtcca atctctgatg
    14221 gcggtaaaaa gtctggcagg agcagtggta gaagccagca aatctatgaa ataccaaggg
    14281 ctcttcttgg aaaaagaaag cagttattta ggcgaatttt ataacaaaaa caaggcgaat
    14341 caactgacag atgaggaatt tcagctccta ctggactaca atgcctatct ttacaagaaa
    14401 gctgctgaga agattttagc aggccggttc gccatcaatc cttatactga aaatggcaga
    14461 agcattgccc catacgtcca gcaacatcag gctattacag gctttgaagc caattaccat
    14521 ctgggccaag cccgtttcct agaaaagttg gacctagctg atggcaagcg tctggtcgga
    14581 gaaaaactca agcaagcttg gcttgaaaaa ataagagagg agttgaatcg atgaagctta
    14641 ttcccttttt aagtgaggag gagattcaaa aactgcaaga agcagaagca aattcgagca
    14701 aggaacagaa gaaaactgcc gagcaaatcg aagctatcta cacttctggc cagaatatcc
    14761 tggtctcagc atcggctggt tctggaaaga cctttgtcat ggcagagcgc attctggacc
    14821 aattggcgcg tggtgtcgaa atttctcaac tctttatctc aacctttacc gtcaaggctg
    14881 caaatgaact taaagaacgt ttagagaaaa aaatcagcaa gaaaatccaa gaaacagatg
    14941 atgtcgacct caaacaacac ttgggacgcc agttggcaga cctaccaaac gctgccatcg
    15001 gaaccatgga ctctttcaca caaaaattcc ttggcaaaca tggttatctg cttgatattg
    15061 cacctaattt ccgtatttta caaaaccaaa gcgagcaact tcttctcgaa aacgaagtct
    15121 ttcatgaggt ctttgaagcg cattaccaag gtaaacagaa agagaccttt agtcatttgc
    15181 tgaaaaactt tgctgggcgt ggcaaggacg aacggggtct gcgccagcag gtctataaaa
    15241 tctatgactt cctccaatcc accagtaatc ctcaaaagtg gctgagtgaa tctttcctca
    15301 aaggctttga gaaagctgat tttaccagtg aaaaagaaaa actgactgag caaatcaaac
    15361 aagccctttg ggatttggaa agctttttcc gttaccatct ggataacgat gccaaggagt
    15421 ttgcaaaggc tgcctattta gaaaatgttc agttaattct ggatgaaatt ggctccctaa
    15481 atcaggagtc cgatagtcag gcttatcagg cagtgcttgc gcgtgttgtc gccatctcta
    15541 aggagaaaaa cggtcgagct ctgactaatg ccagtcgtaa ggctgatttg aagcccctgg
    15601 ctgatgccta caacgaagag agaaagaccc agtttgctaa actaggacaa ttatcagacc
    15661 agataaccat tctcgactat caagaacgtt atcatcaaga cacatgggaa ctagctaaaa
    15721 ccttccaaac ctttatgagt cattttgtgg aggtttatcg tcagcgcaaa cgccaggaaa
    15781 atgcctttga attcgctgat atcagccatt acaccattga gattttagag aatttcccac
    15841 aagttcgtga gtcttatcag gagcgcttcc atgaagtcat ggtcgatgag tatcaggata
    15901 ccaaccatat tcaagaacgg atgctggaat tgttgtctaa tggccacaat cgctttatgg
    15961 tgggagatat caagcaatcc atctatcgtt tccgtcaggc agacccgcag attttcaatg
    16021 agaaattcca acgctatgcg caaaatcccc aagaaggcaa gctcattctc ctcaaggaaa
    16081 atttccgtag tagttcagaa gtgctgtcag caaccaatga tgtctttgaa cgtctcatgg
    16141 accaagaggt cggcgaaatc aactatgata acaagcacca gcttgttttt gccaatacca
    16201 aactgactcc caatccagac aacaaggcag aatttctcct ctacgacaag gacgatacag
    16261 gtgaggaaga agagagtcaa acagaaacga aactaacagg cgaaatgcgc ttagttatca
    16321 aggagattct gaaacttcat caagaaaaag gtgttgcctt taaggaaatt gcccttctga
    16381 cctccagccg cagtcgtaat gaccagattc tcctcgccct gtctgagtac ggaattcctg
    16441 tcaaaactga cggagagcaa aacaattatc tccaatccct agaagtgcaa gtcatgctag
    16501 acactcttcg tgtcattcac aatcccctgc aagactacgc cttggttgcc cttatgaagt
    16561 ctccaatgtt tggttttgat gaggatgagc tagcacgttt gtcccttcag aaagcagagg
    16621 ataaagtcca cgaaaatctc tatgagaaac tggtcaatgc acaaaaaatg gcaagtagtc
    16681 aaaaaggctt gattcacaca gctctagctg aaaaactaaa gcaattcatg gatatcctag
    16741 cttcttggcg cttgtatgcc aaaacccatt ctctctatga cttgatttgg aagatttaca
    16801 acgaccgttt ttattatgac tatgttgggg ctttgccgaa tggtcctgct aggcaggcca
    16861 atctctatgc cctagcactg cgtgctgatc aatttgaaaa gagcaatttc aaaggtttgt
    16921 cgcgttttat tcgtatgatt gaccaagtct tagaagccca gcacgatttg gcaagcgtag
    16981 ccgtcgcacc gccaaaagat gcagtagagc tcatgaccat ccacaagagt aaagggctgg
    17041 agtttcctta catctttatc ctcaatatgg atcaagattt caacaagcaa gactctatgt
    17101 cagaagtcat tctcagtcgt cagaatggtc ttggtgtcaa atatattgcc aagatggaga
    17161 caggggcagt agaagaccac tatcctaaaa ccatcaaact ctccattcct agtctgacct
    17221 ataggcagaa cgaagaggaa ttacagctag caagctattc tgagcagatg cgtttgctgt
    17281 atgttgctat gacgcgggct gagaaaaagc tctatcttgt cggcaagggt tctcgtgaaa
    17341 agctggaatc caaggaatac ccagcagcca aaaatgggaa actaaatagc aatactagac
    17401 tgcaagcacg gaatttccaa gattggcttt gggctatcag taaagtgttt actaaggaca
    17461 agctcaactt tagttatcgt tttattggcg aagatcagtt gaccagagaa gctatcggag
    17521 agttggaaac caagagtcct ctccaagata gctcccaagc agacaatcgt cagtcagata
    17581 ccatcaaaga agctctggaa atgctgaagg aggtggaagt ttataatact cttcaccgcg
    17641 cagctattga acttcctagt gttcaaaccc caagtcaaat caagaaattc tacgaaccag
    17701 ttatggatat ggaaggtgtc gagattgctg gtcaaggtca gtcagtaggc aagaaaatca
    17761 gcttcgattt gccagatttt tcaaccaaag aaaaggtaac tggagctgag attggtagtg
    17821 ctactcacga actcatgcag agaattgacc tcagccagca actaaccctt actagcctaa
    17881 cagaaacact caaacaagtt caaactagcc aagctgtcag agacaagatc aatcttgata
    17941 aaattcttgc tttctttgac acagcactcg gtcaggaaat tcttgctaat accgaccatc
    18001 tctatcgcga gcaacctttc tccatgctca aacgagacca aaagagtcag gaagactttg
    18061 ttgtccgtgg tatccttgat ggctatctgc tttacgaaaa caaaattgtt ctgttcgact
    18121 acaagacaga ccgctatgat gaaccaagtc aactcgtaga ccgctatcgt ggtcagttag
    18181 ctctatacga agaggcttta tcacgagcct attcgattga aaatattgaa aaatacttga
    18241 ttttactcgg taaagacgag gttcaagttg taaaagtata acttatactc ttcgaaaatc
    18301 tcttcaaacc acgtcagctt cgccttgctg tatatatggt tactgacttc gtcagttcta
    18361 tccacaacct caaaacagtg ttttgagctg actgcggcta gctttctagt ttgctctttg
    18421 atttttattg agtattagaa aggagacctc atgacacttc cagttagaaa atccctgcac
    18481 gatgcagttt tacaggcttc gaaagcggat acttgggaac aagctaccaa ggaatggaat
    18541 gaagtttcct tgatttttaa cggtatcggc cgtagcaatt gtgtctgtgg aaatgccatc
    18601 aaatacgctt atgaactctt taacggtgtc acaggccaac gcctctttcc aattggtagc
    18661 gactgtgttc gtcattttta tcgattgtcc cttgaccagc aattggaaga ggaagaaaaa
    18721 ctgctcagaa aggttgaaaa tctaaccaga aaagctcaga aaaaggaaaa aatcaaggtc
    18781 aataaaagtg actttgacga gcgacttcta aaatggctct gggaaaaagg tgttttcaaa
    18841 cccaatcgtg gcaatcaatt tgcgcctgag agagactacc agcttttcct agaagtcttt
    18901 cagggaggaa gttggaccaa ggcggaacca aagaaaaagg ctcggatgga agaagtcctt
    18961 gaaaagtgta tcaaaccctt tttacttggg aaatcggatg accaactcta ccttgtcaag
    19021 ctaggcaagg agaaaattga ctacgaacaa gaactccgta tccaggcaga gaaagaacgc
    19081 aagaagaggg ataaaatcgc caagcaatat gcagacaatc tggttctagc catgggaccc
    19141 gcagagcgtg cttatcaaga ttactttggc tttacagaga ccctgactca agaagaacgc
    19201 aagtgggaaa aaattctttt tggtaaaaat agagcagaac gggatatcaa ggccaaacaa
    19261 taccaaaaag agctggaaaa agaccaacga attgccagtc aggatccaat tgaaagaaaa
    19321 cagaagcaga cttggctcct caattcctat tttcgtgagc ttcctgaaga aaaagctcga
    19381 ttttctaggc tcttattaga atatcgaaaa agtggtgaag tacccttttc aactgaatac
    19441 ctgtccgatc atctcatcga ctttttctat aaaatgaaag cctttgaatt tgaaatcgca
    19501 ccagaacaag tccgagattt tctaaaaaaa agcctgcagg aagaccatcg ctcatcagca
    19561 caaggaagct ggatagaagg aattctcctc aactgcctca aaccattttt agaacgatta
    19621 gtgatatgag taacacctac cgtgtaaatt tcatggtagg tgttattgta cctcaaaata
    19681 atataaaaca aagtatgaaa gcgcatctca attttaagac ttttttgtaa attaagagta
    19741 taattaaggt atactgcct
//
LOCUS       DAVIME010000039        19738 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVIME010000039 DAVIME010000000
VERSION     DAVIME010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19738
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.039"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(94..2253)
                     /locus_tag="VV588_001524"
     CDS             complement(94..2253)
                     /locus_tag="VV588_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU7083845.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(2250..2846)
                     /gene="recU"
                     /locus_tag="VV588_001525"
     CDS             complement(2250..2846)
                     /gene="recU"
                     /locus_tag="VV588_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU7083846.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            2912..3439
                     /locus_tag="VV588_001526"
     CDS             2912..3439
                     /locus_tag="VV588_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU7083847.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            3509..3838
                     /gene="gpsB"
                     /locus_tag="VV588_001527"
     CDS             3509..3838
                     /gene="gpsB"
                     /locus_tag="VV588_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU7083848.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            3859..4239
                     /gene="rnpB"
                     /locus_tag="VV588_001528"
     ncRNA           3859..4239
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VV588_001528"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4324..5481
                     /locus_tag="VV588_001529"
     CDS             4324..5481
                     /locus_tag="VV588_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU7083849.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MASGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            5494..6888
                     /gene="mapZ"
                     /locus_tag="VV588_001530"
     CDS             5494..6888
                     /gene="mapZ"
                     /locus_tag="VV588_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU7083850.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            6964..8388
                     /gene="gndA"
                     /locus_tag="VV588_001531"
     CDS             6964..8388
                     /gene="gndA"
                     /locus_tag="VV588_001531"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU7083851.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSHKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVYASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            8400..9089
                     /locus_tag="VV588_001532"
     CDS             8400..9089
                     /locus_tag="VV588_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083852.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVAYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            9187..10203
                     /gene="cbpC"
                     /locus_tag="VV588_001533"
     CDS             9187..10203
                     /gene="cbpC"
                     /locus_tag="VV588_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU7083853.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGQFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEPKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYFGNKWYYLRSSG
                     AMVTGWYQDGLTWYYLNAGNGDMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNG
                     EWVQ"
     gene            10325..11203
                     /gene="mvk"
                     /locus_tag="VV588_001534"
     CDS             10325..11203
                     /gene="mvk"
                     /locus_tag="VV588_001534"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU7083854.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFWVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            11185..12138
                     /gene="mvaD"
                     /locus_tag="VV588_001535"
     CDS             11185..12138
                     /gene="mvaD"
                     /locus_tag="VV588_001535"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU7083855.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            12125..13132
                     /locus_tag="VV588_001536"
     CDS             12125..13132
                     /locus_tag="VV588_001536"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU7083856.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            13116..14126
                     /locus_tag="VV588_001537"
     CDS             13116..14126
                     /locus_tag="VV588_001537"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU7083857.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDNS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            14203..14901
                     /locus_tag="VV588_001538"
     CDS             14203..14901
                     /locus_tag="VV588_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU7083858.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            14898..15893
                     /locus_tag="VV588_001539"
     CDS             14898..15893
                     /locus_tag="VV588_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU7083859.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FFFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            15907..16539
                     /locus_tag="VV588_001540"
     CDS             15907..16539
                     /locus_tag="VV588_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7083860.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            16540..16781
                     /locus_tag="VV588_001541"
                     /pseudo
     CDS             16540..16781
                     /locus_tag="VV588_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            16763..17017
                     /locus_tag="VV588_001542"
     CDS             16763..17017
                     /locus_tag="VV588_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU7083861.1"
                     /translation="MAANYLKAMQSYLKETDLPKLEQLVVTKSWWDTVDILDRVVGSL
                     VYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLAS"
     gene            17042..17308
                     /locus_tag="VV588_001543"
                     /pseudo
     CDS             17042..17308
                     /locus_tag="VV588_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            17458..17697
                     /locus_tag="VV588_001544"
     CDS             17458..17697
                     /locus_tag="VV588_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083862.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            17778..18599
                     /gene="cbpG"
                     /locus_tag="VV588_001545"
     CDS             17778..18599
                     /gene="cbpG"
                     /locus_tag="VV588_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU7083863.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            18618..19640
                     /gene="cbpF"
                     /locus_tag="VV588_001546"
     CDS             18618..19640
                     /gene="cbpF"
                     /locus_tag="VV588_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEU7083864.1"
                     /translation="MKLLKKMMQIALATFFFGLLATNTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSQAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLNPATGI
                     MQTGWQYLGNRWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQESSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAINTTVGGYYLNY
                     NGEWVK"
BASE COUNT         5873 a         3469 c         4635 g         5761 t
ORIGIN      
        1 aagcctgaga agatgccttc tcaggctttt gttaagcaca taaatacaat agtgctatga
       61 caaaatcacc cagaaaaatc tgggtgataa atgttatggt tgtgctggtt gaggattctg
      121 attttgttga tcaggggttg tatttgattg ttgcgtatta ttgttaggat tggtagtcgt
      181 actattattt gtgcttggag tggttgagct agactgtgaa gttgaactat ctgatgatga
      241 gcttgaactt tcagttgatg ggggttgttg tggagcaggt gagttccacg tagaacgagc
      301 accattttta aatacgaatt ctccatttct gtagagcccc tctggtatat tccaatcctc
      361 tggattgctt ccttcagaca gataggtcat catagagcgg taaactttgg cagcgaccgt
      421 aagaccattg cctacaagtg gtgtcagacg gttagaatag cctgtccata cagccattga
      481 atatttacgc gtatagccag caaatagttc atcaggtgct acaaattgag aggtcttgat
      541 gtggttttca atttcctcgt ctgtatagtt agaggttcct gttttaccag cctgagggag
      601 ccaagcaaga taggcatttc gtccagttcc ataactcaag actgttttca tcatgtcggt
      661 catcatatag gctgtcgttt ccttcatggc acgagttccg acattagaga actctttttc
      721 actcccatca ctaaagacga ctttatggat atacattggt ttatagtaag ttccaccatt
      781 tgcaaaggca gcgtaagcag cagccatctt ttcactactt gctccatatt ttttgtctga
      841 ttcggttgtg ttacttgaaa tggcatttga gtagtgaata cttgggtagt cgattccgag
      901 accatttagg aaagtcttgg cgcggttgag tccgaccttg tttagagttt ccacggctgg
      961 gacgtttcgc gattgttgca gggcgtattg caaggtgatg ttgccaaagt agcccctatc
     1021 ccagttataa acaggggtat ttgtcccagg gtagttatag ggctcatcgt gaacgatagt
     1081 agcagttgaa tcgtagatac cgtactccaa ggcaggagca tagtctgtga tcggtttcat
     1141 agttgatccc cagtcgcggt ttgtttctac tgcttggtta attccgaagg aaacattact
     1201 tgactgatgg cgtgctccta gctgggcaat gactttaccg ttagaaacat caacaatggt
     1261 agaagcgact tgcaattcat cgtctggata ggcaacgtat tcgtctgtat tgtaaatatc
     1321 ccacagatgt ttttgagctt cttggtctac atttgtgtag acatccatcc cagttgtgag
     1381 caggttatag cctgtttctt cttcaacttg attgatgact tccttgaggt aattatccat
     1441 gtaagcaggg taattacttg ctgatttgag actttgtagt ccatcagtaa ttggtgtatt
     1501 gactgctttc tcatactgtt cagcagagat gtagccttga tttttcattt cagataagac
     1561 caagtttcgg cggtcttggg ctgcttctgg atgtgaatag gggtcatatt ggtttggtgc
     1621 ctgaggcatt ccagccagca aggctaactg aggtaaactt aaattattga ggtctttacc
     1681 atagtagttt tgagctgctg tctgcattcc atagttccca ttagacatgt agaccttatt
     1741 tatatagtag gtcaagattt cttgcttggt tgctttttgt tctaactgaa tcgctaacca
     1801 agcttcctga gccttacgag aaatagtctg gtcggaagtc gaagttgaaa agtaagtcaa
     1861 cttaatcaac tgttgagtga gagttgatcc accttggagg gaattgcttt gcagattgcg
     1921 caagaaagct cccaggatac ggatggtatc aatccccctg tggtcgaaga agcgatggtc
     1981 ttcgatagaa acgattgctt taaccaaatc tgtgggaata tcattagctt gggcattgac
     2041 gcggcgttca gaacccaagt cagcaatgag ttgattttta ttgtcgtaga ttttactaga
     2101 agttgttgca actagtttac tctcggatag gctaggagcc ttgctaacgt agtagaaaaa
     2161 aactcctccg cctaagacaa tggctgcgat aaccaagctt aagaagctaa tgctcagata
     2221 cttgattagg cgcagaatcg ttggtttgtt catcttgttt taccacctaa taaatgttct
     2281 ttgataacat tgagataagg aatttgaggg aaggcaccag ccttgatttc atatccatat
     2341 tctcgaatat attcaagtgg cattgatttt tgtcccttat cttgatgata gaagcgaatc
     2401 aaatcgaatg ccggcaataa gtaggtttct tgctgagaag aaaagtgaag aaggacaaag
     2461 cagattcctt gttgagcaag gacttgttcc atatgctgaa tctgatgtgg atgaaaattt
     2521 ttcatcggaa tcgcacgttt ttgttttgtt tccttgactt caaagtcgat gtaatatcca
     2581 ttataaacgc cagaatagtc cgtcgttgaa gcttgtcgaa aataggcttc aacaatcttg
     2641 gcacgacttc gttgtggata gtccacttgt acgatttgaa taggagttgg tttcttatgt
     2701 ataacagcca agccctgaga caaatagtag tcgttggtag cattgatcat cttttcaaaa
     2761 gacattcctc gatttgcgaa atttttgggt tgagaaagag atgtttgtct tttttgtgat
     2821 gaaactttat gtggatagtt gaccataatt ctccttattg gtacaataac atcactttat
     2881 tataccataa tttgcacaga aagggttaaa aatggctaca gctttggttt taggctattc
     2941 tgcttttgat ttgggtttat tttctgataa ggatcctcgt cttaaattga ttaaaaaagc
     3001 gatacgtaaa gatttagagg ctatggcagc agatggggtg tcttggcttg tgtttacagg
     3061 gactttgggc tttgaatatt gggttttaga ggttgctcag gagatgaaaa ccgaatacgg
     3121 tttccagttg gccaccattt ttgcttttga aacccatggg gaaaattgga atgaaggcaa
     3181 tcagatgaaa ctgagtcgct ttaagcaggt agactttgtc aaatatgcct atcctcgcta
     3241 tgaacacaag gggcagttaa gagattacca gcagtttttg ctggaaaaca cgactagttc
     3301 ctatcttttt tatgatgaag aaaatgaaac aaaactagct tatttttacc aaaagatgaa
     3361 aaatcaagag gactatttta taaagagatt aacatttgat caattaaatg aacttgctga
     3421 aaatttttcc gaaaattgaa gctttgacct tgatttttgt ttgccttttt ttatataata
     3481 atactagcaa gcgagaatgg agagagacat ggcaagtatt attttttcag cgaaagatat
     3541 ttttgaacaa gagtttggac gtgaagtccg tggctataat aaagtagaag ttgacgagtt
     3601 tttagacgat gtcatcaagg actatgaaac ctatgctgcc ttggtcaagt cacttcgtca
     3661 ggaaattgcg gatttgaagg aagaattaac tcgtaaaccg aaaccttcac cagttcaagc
     3721 agaacccctt gaagcggcaa ttacaagttc tatgacgaat tttgatattt tgaaacgcct
     3781 gaatagattg gaaaaagaag tttttggtaa acaaatttta gataactcag atttttaagt
     3841 agttatttga gatgtgcaat ttttggataa tcgcgtgagg agaattgctt ctcatgagga
     3901 aagtccatgc tagcacaggc tgtgatgcct gtagtgtttg tgctaggcga aaccataagc
     3961 ctagggacga gaaatcgtta cggcagttga aatggctaag tccttggata ggccagagta
     4021 ggcttgaaag tgccacagtg acgaagtctt tctggaaaca gagagagtgg aacgcggtaa
     4081 acccctcaag ctagcaaccc aaattttggt cggggcatgg agtacgcgga aacgaacgta
     4141 gtattctgac tgctatcagc tagagctgtt agtggtagac agatgattat cgaaggaagt
     4201 ggtcctagtc acttctggaa caaaacatgg cttatagaaa attgcatata ggttggggct
     4261 gagaaatttt ctcaacctca ttttttaaag tggacatata gaaaggtctt gcaagactgt
     4321 aacatgaaaa aagaatttaa tttaattgca actgtggcag cagggcttga ggctgtcgtt
     4381 ggtcgtgaag tgcgagagtt gggctacgat tgtcagattg aaaatggacg tgttcgtttt
     4441 caaggagacg tgagagctat tatcgaaacc aacctttggc tgcgggcagc agatcgtatc
     4501 aaaattatcg taggaacgtt ccctgctaag acttttgaag agctatttca gggagttttc
     4561 gctttagatt gggaaaatta tttaccactt ggagctcggt tcccgatttc aaaagctaaa
     4621 tgtgttaagt ccaaacttca caatgagccc agtgttcagg ctatttctaa gaaagctgtt
     4681 gtcaagaaat tgcagaaaca ctatgctcgc ccagaagggg ttcctctgat ggagaatggc
     4741 ccagagttta agattgaggt ctctattctc aaagatgtgg caactgtcat gattgatacg
     4801 accgggtcta gcctctttaa acgtggttat cgtaccgaaa aaggtggcgc tcctatcaag
     4861 gaaaatatgg cagcagccat tttacaactt tctaactggt atccagacaa gcctttgatt
     4921 gatccgacct gtggttcggg gactttctgt attgaggcag ttatgattgc tagaaagatg
     4981 gcgtcaggtc ttcgtcgctc ttttgcattt gaggaatgga actggatcag cgatcgcttg
     5041 attcaagaag tgcgcacaga agcggctaaa aaagtagacc gtgagcttga gctggatatc
     5101 atgggctgtg atattgatgc tcgcatggtg gaaattgcta aggccaatgc tcaggcagct
     5161 ggtgttgcag gagacattac ttttaagcag atgcgcgtgc aggatttatg ttccgataaa
     5221 atcaatggag taatcatttc caatccgcct tatggtgaac gtttgtcaga tgatgcaggg
     5281 gtgaccaagc tctatgctga gatggggcaa gtatttgcac cgctgaaaac ttggagcaaa
     5341 tttatcctga ctagtgatga agcttttgaa agcaagtatg gtagccaagc agataagaag
     5401 cgtaagttat acaacggaac cttgaaagtg gatctgtatc aatattttgg tcagcgtgtc
     5461 aaacggcaag aggtaaaata gaaagggata ctcatgagta aaaaaagacg aaatcgtcaa
     5521 aaaaaagaag gtcaagaacc gcaatttgat tttgatgaag caaaagagct aacagttggt
     5581 caagctattc gtaaaaatga agaagtggaa gcaggagtct tgcctgagga ttccattttg
     5641 gacaagtatg ttaagcaaca cagagatgaa attgaggcgg ataagtttgc gactcgtcaa
     5701 tacaaaaaag aggagttcgt tgaaactcag agtctggatg atttaattca agagatgcgt
     5761 gaggctgtag agaagtcaga agcttcttcg gaggaagttc catcttctga agacatctta
     5821 ctacccttgc ctctggacga tgaggagcaa ggcttggatc ctctattgct agatgatgaa
     5881 aatccaacag aaatgactga agaagtggaa gaggagcaaa acctttctcg tctggatcaa
     5941 gaggactcag aaaagaaaag taaaaaaggc tttattttga ccgttttggc gcttgtatca
     6001 gtaattattt gtgtcagtgc ttattatgtc taccgtcaag tggctcgttc gaccaaggaa
     6061 attgaaactt ctcaatcaac tacagccaat caatcggatg tggatgattt taatacactt
     6121 tatgacgcct tttacacaga tagcaataaa acggctttga aaaatagcca gtttgataaa
     6181 ctgaatcaac tcaagacttt acttgataag ctggaaggta gtcgtgaaca tacgcttgcc
     6241 aaatctaaat atgatagtct agcaacgcaa atcaaggcta ttcaagatgt caatgctcaa
     6301 tttgagaaac cagctattgt ggatggtgtg ttggatacca atgccaaagc caaatcggat
     6361 gctaaattta cggatattaa aactggaaat acggagcttg ataaagtgct agataaggct
     6421 atcagtcttg gtaagagcca gcaaacaagt acttctagct caagttcaag tcaaactagc
     6481 agctcaagtt caagtcaagc aagttcaaat acgactagtg agccaaaacc aagtagttca
     6541 aatgagacta gaagtagtcg cagtgaagtc aatatgggtc tctcgagtgc aggggttgct
     6601 gttcaaagaa gtgccagtcg tgttgcctat aatcagtctg ctattgatga tagtaataac
     6661 tctgcctggg attttgcgga tggtgtcttg gaacaaattc tagcgacttc acgttcacgt
     6721 ggctatatca ctggagacca atatatcctt gaacgtgtca atatcgttaa cggcaatggt
     6781 tattacaacc tctataagcc agatggaacc tatctcttta cccttaactg taagacaggc
     6841 tactttgtcg gaaatggcgc tggtcatgcg gatgacttgg actactaagc agtcgttaca
     6901 aaattctttc ttttcaaaag taaaaatgat aaaataaaac aaatgaaaca agaggagtgt
     6961 caaatgacaa aagctaactt tggtgtcgta ggtatggccg taatgggtcg taaccttgcc
     7021 cttaatattg aatcacgtgg ttacacagtt gctatctaca accgtagtaa agaaaaaacg
     7081 gaagatgtga ttgcttgcca tcctgaaaag aattttgtac caagctatga cgttgaaagt
     7141 tttgtaaact caatcgaaaa acctcgtcgt atcatgctga tggttcaagc tggacctggt
     7201 acagatgcta ctatccaagc ccttcttcca caccttgaca agggtgatat cttgattgac
     7261 ggaggaaaca ctttctacaa agataccatc cgtcgtaatg aagaattggc aaactcaggt
     7321 atcaacttta tcggtactgg agtttctggt ggtgaaaaag gtgcccttga aggtccttct
     7381 atcatgcctg gtggacaaaa agaggcctac gaattggttg cggatgttct tgaagaaatc
     7441 tcagctaaag caccagaaga tggcaaacca tgtgtgactt acatcggccc tgatggagct
     7501 ggtcactatg tgaaaatggt tcacaatggt attgagtacg gtgatatgca attgatcgca
     7561 gaaagctatg acttgatgca acacttgcta ggcctttctg cagaggatat ggctgaaatc
     7621 tttactgagt ggaacaaggg tgaattagac agctatttga tcgaaatcac agctgatatc
     7681 ttgagccata aagacgatga aggccaagat ggaccaatcg tagactacat ccttgatgct
     7741 gcaggtaaca agggaactgg taaatggact agccaatcat ctcttgacct tggtgtacca
     7801 ttgtcactga ttactgagtc agtgtttgca cgctacattt caacttacaa agaagaacgt
     7861 gtatatgcta gcaaggtgct tccaaaacca gctgccttca actttgaagg agacaaggct
     7921 gaattgattg aaaagatccg tcaagccctt tacttctcaa aaatcatttc atacgcacaa
     7981 ggatttgctc aattgcgtgt agcctctaaa gaaaacaact ggaacttgcc atttgcagat
     8041 atcgcatcta tctggcgtga tggctgtatc atccgttctc gtttcttgca aaagattaca
     8101 gatgcttaca accgcgatgc agatcttgcc aaccttcttt tggacgagta cttcttggat
     8161 gttactgcta agtatcaaca agcagtgcgt gatatcgtag ctcttgcggt tcaagctggt
     8221 gtgccagtgc caactttctc agcagctatt acttactttg atagctaccg ttcagctgac
     8281 cttccagcta acttgatcca agcacaacgt gactactttg gtgctcacac ttaccaacgt
     8341 aaagacaaag aaggaacctt ccactactct tggtatgacg aaaaataagt aggtcagcca
     8401 tggggaaacg gattttatta cttgagaaag aacgaaatct agctcatttt ttaagtttgg
     8461 aactccagaa agagcagtat cgggttgatc tggtagagga ggggcaaaaa gccctctcca
     8521 tggctcttca gacagactat gatttgatgt tattgaacgt taatctggga gatatgatgg
     8581 ctcaggattt tgcagaaaaa ttgagtcgaa ctaaacctgc ctcagtcatc atgattttag
     8641 atcattggga agacttgcaa gaagagctgg aagttgttca gcgttttgca gttgcataca
     8701 tttataagcc agtccttatc gaaaatctgg tagcgcgtat ttcggcgatc ttccgaggtc
     8761 gggacttcat tgatcaacac tgcagtctga tgaaagttcc aaggacttac cgcaatctta
     8821 ggatagatgt tgaacatcac acggtttatc gtggtgaaga gatgattgct ctgacccgcc
     8881 gtgagtatga ccttttggcg acacttatgg gaagcaagaa agtattgact cgtgagcaat
     8941 tgttggaaag tgtttggaag tatgaaagtg cgaccgagac aaatatcgta gatgtctata
     9001 tccgctatct acggagcaag cttgatgtta aaggccaaaa aagctacatt aaaaccgtgc
     9061 gtggtgttgg atataccatg caagaataga taagcagttg cagttgtgta actgcttttt
     9121 tgaggagttt ttatatattg acatgcagtc gggtctttgc tacaatcgtt ttaggaggat
     9181 atatagatga aacttttgaa aaaaatgatg caagttctac tagcagtctt tttctttggt
     9241 ttgctagcta caaatacggt atttgcgaat accacaggtg gccaatttgt tgataaggat
     9301 aatagaaaat attatgtaaa agatgatcat aaagcaatct attggcataa aatagacggt
     9361 aaaacttact attttggtga tattggagag atggttgtcg gttggcaata cttagaaatt
     9421 cctggaacag gttatcgtga taatttattc gataaccaac cagttaatga gattggcctt
     9481 caggagaagt ggtactattt tggacaagat ggtgctttgc tagaacaaac agataaacaa
     9541 gtactagagc caaaaacgtc tgaaaataca ggaaaagtat acggtgaaca atatcctcta
     9601 tctgctgaaa agagaactta ttattttgat aataattatg ctgtaaagac aggctggatt
     9661 tatgaagacg gcaattggta ttatttaaat aagctaggaa attttggcga tgattcttac
     9721 aatccactac caattggtga agttgctaag ggttggactc aagattttca tgttactatt
     9781 gacattgata gaagcaaacc tgctccatgg tactacctag atgcttcagg taagatgctt
     9841 acagattggc aaaaagtaaa cggaaaatgg tattattttg gctcctctgg ttctatggca
     9901 acaggttgga aatatgtacg aggcaaatgg tattacttag ataataaaaa tggtgatatg
     9961 aaaacaggat ggcaatactt tggtaacaag tggtactacc tccgttcatc aggagctatg
    10021 gtaactggct ggtatcaaga tggtttaact tggtactacc taaatgcagg taatggagac
    10081 atgacgacag gttggttcca ggtcaatggc agatggtact acgcttatag ctcaggtgcc
    10141 ttggcagtga atacgaccgt agatggctat tctgtcaact ataatggcga atgggttcaa
    10201 taatgaaaga agcgattgtg aatggaaaca atcgcttttt ttgtgaaaat ataataaaat
    10261 agataggaaa gaattaatac ttgtatgaaa aataagacgt tttttcgtct agtaaaagga
    10321 aaaaatgaca aaaaaagttg gtgtcggtca ggcacatagt aagataattt taatagggga
    10381 acatgcggtc gtttacggtt atcctgccat ttccctgcct cttttggagg tggaggtgac
    10441 ctgtaaggta gttcctgcag agagtccttg gcgcctttat gaggaggata ccttgtccat
    10501 ggcggtttat gcctcactgg agtatttgaa tatcacagaa gcctgcattc gttgtgagat
    10561 tgactcggct atccctgaga aacgggggat gggttcgtca gcggctatca gcatagcggc
    10621 cattcgtgca gtatttgact actatcaggc tgatctgcct catgatgtac tagaaatctt
    10681 ggtcaatcga gctgaaatga ttgcccatat gaatcctagt ggtttggatg ctaagacctg
    10741 tcttagtgac caacctattc gctttatcaa gaacgtagga tttacagaac ttgagatgga
    10801 tttatccgcc tatttggtga ttgccgatac gggtgtttat ggtcatactc gtgaagccat
    10861 ccaagtggtt caaaataagg gcaaggatgc cctaccgttt ttgcatgcct tgggagaatt
    10921 aacccagcaa gcagaagttg cgatttcaca aaaagatgct gaaggactgg gacaaatcct
    10981 cagtcaagcg catttacatt taaaagaaat tggagtcagt agccctgagg cagacttttg
    11041 ggttgaaacg actcttagcc atggtgctct gggtgccaag atgagcggtg gtgggctagg
    11101 aggttgtatc atagccttgg taaccaattt gacacacgca caagaactag cagaaagatt
    11161 agaagagaaa ggagctgttc agacatggat agagagcctg taacagtacg ttcctacgca
    11221 aatattgcta ttatcaaata ttggggaaag aaaaaagaaa aagagatggt gcctgctact
    11281 agcagtattt ctctaacttt ggaaaatatg tatacagaga cgaccttgtc gcctttacca
    11341 gccaatgtaa cagctgacga attttacatc aatggtcagc tacaaaatga ggtcgagcat
    11401 gccaagatga gtaagattat tgaccgttat cgtccagctg gtgagggctt tgtccgtatc
    11461 gatactcaaa acaatatgcc tacggcagcg ggtctgtcct caagttctag tggtttgtcc
    11521 gccctggtca aggcttgtaa tgcttatttc aagcttggat tggatagaag tcagttggca
    11581 caggaagcca aatttgcctc aggttcttct tctcggagtt tttatggacc actaggagcc
    11641 tgggataagg atagtggaga aatttaccct gtagagacag acttgaaact agctatgatt
    11701 atgttggtgc tagaggacaa gaaaaaacca atctctagcc gtgacgggat gaaactttgt
    11761 gtggaaacct cgacgacttt tgacgactgg gttcgtcagt ctgagaagga ctatcaggat
    11821 atgctgattt atctcaagga aaatgatttt gccaagattg gagaattaac ggagaaaaat
    11881 gccctggcta tgcatgctac gacaaagact gctagtccag ccttttctta tctgacggat
    11941 gcctcttatg aggctatgga ctttgttcgc cagcttcgtg agaaaggaga ggcctgctac
    12001 tttaccatgg atgctggtcc caatgttaag gtcttctgtc aggagaaaga cttggagcat
    12061 ttatcagaaa ttttcggtca tcgttatcgc ttgattgtgt caaaaacaaa ggatttgagt
    12121 caagatgatt gctgttaaaa cttgcggaaa actctattgg gcaggtgaat atgctatttt
    12181 agagccaggg cagttagctt tgataaagga tattcccatc tatatgaggg ctgagattgc
    12241 tttttctgac agctaccgta tctattcaga tatgtttgat ttcgcagtgg acttaaggcc
    12301 taatcctgac tacagcttga ttcaagaaac gattgctttg atgggagact tcctcgctgt
    12361 tcgcggtcag aatttaagac ctttttccct aaaaatctgt ggcaaaatgg aacgagaagg
    12421 gaaaaagttt ggtctaggtt ctagtggcag cgtcgttgtc ttggttgtca aggctttatt
    12481 ggctctctat aatctttcgg ttgatcagga gctcttgttc aagctgacta gcgctgtctt
    12541 gcttaagcga ggagacaatg gttccatggg cgaccttgcc tgtattgtgg cagaggattt
    12601 ggttctctac cagtcatttg atcgccagaa ggcggctgct tggttagaag aagaaaactt
    12661 ggcgacagtt ctggagcgtg attggggatt ttttatctca caagtgaaac caactttaga
    12721 atgtgatttc ttagtgggat ggaccaagga agtggctgta tcgagtcaca tggtccagca
    12781 aatcaagcaa aatatcaatc aaaatttttt aagttcctca aaagaaacgg tggtttcttt
    12841 ggtcgaagcc ttggagcagg ggaaagccga aaaagttatc gagcaagtag aagtagccag
    12901 caagctttta gaaggcttga gtacagatat ttacacgcct ttgcttagac agttgaaaga
    12961 agccagtcaa gatttgcagg ccgttgccaa gagtagtggt gctggtggtg gtgactgtgg
    13021 catcgccctg agttttgatg cgcaatcaac caaaacctta aaaaatcgtt gggccgatct
    13081 ggggattgag ctcttatatc aagaaaggat aggacatgac gacaaatcgt aaggacgagc
    13141 atatcctcta tgcccttgag cagaaaagtt cctataatag ctttgatgag gtggagctga
    13201 ttcattcttc cttgcctctt tacaatctgg atgaaatcga tctttcgaca gagtttgctg
    13261 gtcgaaagtg ggactttcct ttttatatca atgccatgac tggtggaagt aataagggaa
    13321 gagaaatcaa tcaaaagctg gctcaggtgg cggaatcctg tggtatttta tttgtaacgg
    13381 gttcttatag cgcagccctc aaaaatccaa cggataattc tttttctgtc aagtctagtc
    13441 atcccaatct cctccttgga accaatattg gattggacaa acctgtcgag ttaggacttc
    13501 agactgtaga agagatgaat cctgttctat tgcaagtgca tgtcaatgtc atgcaggaat
    13561 tactcatgcc cgagggagaa aggaagttta gaagctggca atcgcatcta gcagattata
    13621 gcaagcaaat tcccgttcct attgtcctca aggaagtggg ctttggaatg gatgccaaga
    13681 caatcgaaag agcctatgaa ttcggtgttc gtacagtgga cctatcgggt cgtggtggca
    13741 ccagctttgc ctatatcgaa aaccgtcgta gtggccagcg tgattacctc aatcaatggg
    13801 gtcagtctac catgcaggcc cttctcaatg cccaagaatg gaaagataag gtcgaactct
    13861 tggttagtgg aggggttcgg aatccgctgg atatgattaa gtgcttggtt tttggtgcta
    13921 agtctgtggg attgtcacga accgttctgg aattggttga aacctacaca gttgaagaag
    13981 tgattggcat tgtccaaggc tggaaagcag acctacgctt gattatgtgt tcccttaact
    14041 gtgccaccat agcagatcta caaaaagtag actatcttct ttatggaaaa ttaaaagaag
    14101 caaatgatca gatgaaaaag gcgtaaccag cgcctttttt ccatcctcag actgaggtga
    14161 cttttttgaa ttgtgataaa atagaaggga gaggatgaac ctatgagaaa atttaaaatc
    14221 tttttattta tcgaagcctg tcttctgaca ggagctctga ttttgatggt atcagagcat
    14281 ttttcgcgtt ttctgctgat actattcctc tttttgcttt tgattcgcta ctacactggt
    14341 aaagagggga ataatcttct tttagtagcg gcaaccattc tcttcttttt cattgttatg
    14401 ctcaatcctt ttgtgattct agctattttt gttgcggtta tctatagtct ctttcttctt
    14461 tacccgatga tgaaccagga aaaagagcag accaatttgg tttttgaaga ggttgtgacg
    14521 gttaagaagg agaaaaatcg ttggtttgga aatcttcatc atttttcaag ctaccagact
    14581 tgccaatttg atgatatcaa tctctttcgc ttcatgggca aggacactat tcatctggag
    14641 agagtcatct taaccaatca tgacaatgtc attatcctca gaaagatggt aggaacgacc
    14701 aaaatcatcg tacctgtaga tgtggaagtc agtctcagcg ttaactgtct ctatggggat
    14761 ttgacttttt tcaaccagcc caagcgagcc ctccgcaatg aacactatca tcaagaaaca
    14821 aaagactatc tcaagagtaa caagagtgtc aagattttct tgaccactat gattggtgat
    14881 gttgaggtgg ttagaggatg aaaaaacaag cctatgtcat tatcgctctc acctccttcc
    14941 tgtttgtctt ttttttctcc catagcttgc tggaaatact tgattttgac tggtctatct
    15001 ttttgcacga tgtcgaaaaa acagaaaaat ttttcttttt attgttggtt ttcagcatgt
    15061 ccatgacctg tctcttagcc ctgttttggc gagggatcga agagctttct ctaagaaaaa
    15121 tgcaggctaa tctcaagcgt ttattggcag ggcaagaagt ggttcaggtt gtagatccag
    15181 atttggatgc cagtttcaag tccttatcag gtaaacttaa ccttttgaca gaggctcttc
    15241 aaaaagctga aaatcatagc cttgctcagg aagaggaaat catcgagaag gaacggaagc
    15301 gaattgctcg ggatttgcac gatacagtca gtcaggagtt gtttgcggcc cacatgattt
    15361 tatcgggtat cagtcagcag gctttgaaat tggatagaga aaagatgcag acccagttgc
    15421 agagtgtcac agctatttta gaaacagccc agaaggattt gcgggttttg ctcttgcatt
    15481 tgcgaccagt tgaactggag cagaagagct tgatagaagg gattcaaatt cttttaaaag
    15541 agcttgagga caagagtgat cttagggtta gtctcaagca gaatatgacg aaattgccta
    15601 agaaaatcga ggagcatatc ttccgtatcc tgcaagagtt gattagcaat accctccgcc
    15661 atgcccaggc atcttgccta gatgtctacc tctatcagac agatgttgaa ttgcaactga
    15721 aggtggtgga caatgggatt ggtttccagt tagggagctt agacgacttg agttatggac
    15781 tgcgaaatat caaggagcgg gttgaagata tggctggaac agttcaactc ttgacagctc
    15841 ccaagcaagg gctggcggtt gatatccgta ttcctctgtt agataaggaa tgataaagga
    15901 gtaaagatga aaattttact agtagatgac catgaaatgg tccgattggg cttgaaaagc
    15961 tactttgacc tccaagacga tgtagaagtt gtgggtgagg cgtccaacgg gtctcaaggg
    16021 attgacttgg ccttggaact gcgtccagat gtcattgtca tggatattgt catgcctgag
    16081 atgaatggga ttgacgcgac cttagcaatc cttaaagaat ggcctgaagc caagattttg
    16141 attgtgacct cttatttgga caatgaaaaa atcatgccag tcttagatgc tggtgccaaa
    16201 ggctatatgc tcaagacttc tagtgcagat gaattgcttc atgccgtcag taaggtagct
    16261 gctggcgagc tggccattga gcaagaggtt agcaagaagg ttgaatacca ccgcaatcat
    16321 atggaacttc atgaagaatt gactgcgcgt gagcgagatg ttctccaact catcgccaag
    16381 ggctacgaaa atcagcgcat cgcagatgac ctctttatct ctctcaagac ggtcaagacc
    16441 cacgtgtcca atattcttgc caaacttgaa gtcagcgatc gtacccaggc ggctgtctat
    16501 gcctttcagc accatttggt ggggcaagag gagttttaga tgagtttagc agatttactt
    16561 gaggagctag aagcagcaaa agactctaaa aaagcaaggt ccatggaagc ctatatgcgc
    16621 catcaatttt cttttctagg tattgcggtg cctgaaagaa ataaactcta taaaatattt
    16681 tccagaagcg aaaaaaacaa agattatcga ttgggatttt gcagacactt gctgggaaaa
    16741 gaatcctaga aaataccaat atgtggctgc taactatttg aaagcaatgc agtcttatct
    16801 aaaggaaacc gatttgccta agctagagca gttagtcgtg acaaaatcct ggtgggacac
    16861 ggtagatatc ctagatcgag tagtagggag tttggtgtat gaacactctg aactagaaga
    16921 aataatctta atactcttcg aaaatctctt caaaccacgt cagctctatc tgcaacctca
    16981 aaacagtgtt ttgagcaatc tgcggctagc ttcctagttt gctctttgat tttcattgag
    17041 tataaaatgg agcctatcag ataatatctg gctgagacgt gtcgctattg accaccagtt
    17101 gttaagaaaa gagaagacca atactcaatt aatggaaaag attctacttc ataacttgaa
    17161 ccaaacagaa ttttttatca ataaagccat tggctggact ctgcgagact actccaaaac
    17221 gaatcccact tgggtaacat gctttattga gaaaaacaag gaaagaatgg ctgaacttag
    17281 tatcaaagaa gcaagcaagt acctctagcg tgattgaaaa gcgcagtcat taattgaaaa
    17341 gtttacctgt ttatgtgata atggagggta tttaaagaag gtggtagatt tcttgattct
    17401 atagtagatt aagaaattta gaatagtacg ctataattac attaggagga tacaataatg
    17461 aagaaaactg tttataaaaa attgggtatt tcaattattg cgagtacttt attggctagc
    17521 cagttatcga cagtatctgc tttgagtgtt atttctagta caggtgaaga atatgaggta
    17581 agtgagacac tagaaaaagg tccagagtct aatgattctt cattatctga gatttcacca
    17641 acgtatggtt catactacca aaagcaatca gaagtattat cggtaatgat gatttgatta
    17701 aaattgataa tactttacag tatccgtatt cgacttcagc tatggtttta tctaagtatt
    17761 atggagtagc cgatggaatg aatgtagaag ggaggggaag tgcgaatttt attaaagata
    17821 atgtgttaat tacagcggct cacaactact acagacatga ctatgggaaa gaagcggatg
    17881 atatttatgt tcttccggct gttagtccaa gtcaagaact atttggaaag atcaaagtaa
    17941 aggaagttcg ttatttgaag gaatttagaa atttaaattc taaggatgca agggaatatg
    18001 acttggcttt attaattcta gaagagccca ttggtgcaaa attagggact ttgggtcttc
    18061 ctactagtca aaaaaatttg acaggaataa ctgtgactat cacaggctat ccatcatata
    18121 attttaaaat tcatcaaatg tatacagata aaaaacaagt tttaagtgat gatggcatgt
    18181 tcttggatta ccaagttgat actttagagg ggtctagtgg atctacagtt tatgatgcta
    18241 gtcaccgtgt agtaggagtg catactttag gagatggagc taatcaaatt aacagtgcag
    18301 ttaaattaaa tgaacgaaat ttgccattta tttattcggt tcttaaaggt tactctcttg
    18361 aaggatggaa gaaaataaat ggtagttggt accattatag acaacatgat aaacaaacgg
    18421 gttggcagga gataaatgat acttggtatt atttagacag ttccggtaag atgcttacag
    18481 attggcaaaa agtaaatgga aaatggtatt atctcaattc aaatggagca atggttacag
    18541 gtagccaaac tatcgatggt aaagtttata acttcgcttc atctggtgag tggatttaat
    18601 gttggaggat atataaaatg aagcttttga aaaaaatgat gcaaatcgca ctagccacat
    18661 ttttcttcgg tttgttagcg acaaatacag tatttgcaga tgattctgaa ggatggcagt
    18721 ttgtccaaga aaatggtaga acctactaca aaaaggggga tctaaaagaa acctactgga
    18781 gagtgataga tgggaagtac tattattttg atcctttatc cggagagatg gttgtcggct
    18841 ggcaatatat acctgctcca cacaaggggg ttacgattgg tccttctcca agaatagaga
    18901 ttgctcttag accagattgg ttttattttg gtcaagatgg tgtattacaa gaatttgttg
    18961 gcaagcaagt tttagaagca aaaactgcta cgaataccaa caaacatcat ggggaagaat
    19021 atgatagcca agcagagaaa cgagtctatt attttgaaga tcagcgtagt tatcatactt
    19081 taaaaactgg ttggatttat gaagagggtc attggtatta tttacagaag gatggtggct
    19141 ttgattcgcg catcaacaga ttgacggttg gagagctagc acgtggttgg gttaaggatt
    19201 accctcttac gtatgatgaa gagaagctaa aagcagctcc atggtactat ctaaatccag
    19261 caactggcat tatgcaaaca ggttggcaat atctaggtaa tagatggtac tacctccatt
    19321 cgtcaggagc tatggcaact ggctggtata aggaaggctc aacttggtac tatctagatg
    19381 ctgaaaatgg tgatatgaga actggctggc aaaaccttgg gaacaaatgg tactatctcc
    19441 gttcatcagg agctatggca actggttggt atcaggaaag ttcgacttgg tactatctaa
    19501 atgcaagtaa tggagatatg aaaacaggct ggttccaagt caatggtaac tggtactatg
    19561 cctatgattc aggtgcttta gctattaata ccacagtagg tggttactat ttaaactata
    19621 atggtgaatg ggttaagtaa tgaagactaa ttgtaaactg tgatggatac ttaactttgt
    19681 ataataggtg gataaaagtc ttcacaatca aaaaacgcat agtatcaagg tttttctg
//
LOCUS       DAVIME010000040        18876 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVIME010000040 DAVIME010000000
VERSION     DAVIME010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.040"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            171..509
                     /locus_tag="VV588_001547"
     CDS             171..509
                     /locus_tag="VV588_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU7083865.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVKEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            699..2135
                     /locus_tag="VV588_001548"
     CDS             699..2135
                     /locus_tag="VV588_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU7083866.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            2187..2426
                     /locus_tag="VV588_001549"
     CDS             2187..2426
                     /locus_tag="VV588_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU7083867.1"
                     /translation="MIGSIAAILTTFAFLPQVFRIVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2556..2870
                     /locus_tag="VV588_001550"
     CDS             2556..2870
                     /locus_tag="VV588_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU7083868.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            2988..4968
                     /locus_tag="VV588_001551"
                     /pseudo
     CDS             2988..4968
                     /locus_tag="VV588_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
     gene            4978..5292
                     /locus_tag="VV588_001552"
     CDS             4978..5292
                     /locus_tag="VV588_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU7083869.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5323..5829
                     /locus_tag="VV588_001553"
     CDS             5323..5829
                     /locus_tag="VV588_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083870.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LSQFISPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLALSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5909..7255
                     /gene="celB"
                     /locus_tag="VV588_001554"
     CDS             5909..7255
                     /gene="celB"
                     /locus_tag="VV588_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU7083871.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7637..7813
                     /locus_tag="VV588_001555"
     CDS             7637..7813
                     /locus_tag="VV588_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083872.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8214..10427
                     /locus_tag="VV588_001556"
     CDS             8214..10427
                     /locus_tag="VV588_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU7083873.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10649..11125)
                     /locus_tag="VV588_001557"
     CDS             complement(10649..11125)
                     /locus_tag="VV588_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU7083874.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11348..14551
                     /locus_tag="VV588_001558"
     CDS             11348..14551
                     /locus_tag="VV588_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEU7083875.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            14931..15316
                     /gene="tnpA"
                     /locus_tag="VV588_001559"
                     /pseudo
     CDS             14931..15316
                     /gene="tnpA"
                     /locus_tag="VV588_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(15695..16324)
                     /locus_tag="VV588_001560"
     CDS             complement(15695..16324)
                     /locus_tag="VV588_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU7083876.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKKEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDGISEIAQQYVTLR"
     gene            complement(16334..17335)
                     /locus_tag="VV588_001561"
     CDS             complement(16334..17335)
                     /locus_tag="VV588_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU7083877.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(17366..18007)
                     /locus_tag="VV588_001562"
     CDS             complement(17366..18007)
                     /locus_tag="VV588_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU7083878.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(18026..18841)
                     /locus_tag="VV588_001563"
     CDS             complement(18026..18841)
                     /locus_tag="VV588_001563"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU7083879.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6097 a         2973 c         3922 g         5884 t
ORIGIN      
        1 tcttgtttca attgactata aatcgctata agaaaaaatc attttattgg tataaagaag
       61 tgattgaaag taatggcgaa acgttagata attagttcat aaaaaacaag tttagatcct
      121 catctaaact tgttttttta aaattgaagg atgattttgg aggatataag atgacattga
      181 ctattcatgt atattataaa ggtgatggag atagtgcaat aaagtttgca agagaaatgc
      241 ttgatagtgg ccttgttaaa gaaattagaa atcaaaaagg taacttgaaa tacgaatatt
      301 ttttaccaat tgaaaaagag ggaactattc tccttattga tcagtggata aatcaagaaa
      361 ctttagataa acattatcaa tcaaagacaa tgcagaaaat cttagattta agaaaaaaat
      421 atcacttgca gatgcaagtt gaacgttata tagaagatga ttctgggatg ccagaaagcg
      481 ataagtcgtt tatagacaca gggaattaga attattgtga gagtttttgt agtttgaaag
      541 tattgaaaat cgtaaagata tcattacgag aatacaagaa gatattgttc tatttccatt
      601 aaaaattact tctttcctta acaataagga aaaagaatgc gttttcatct tttggtttaa
      661 ggtttataat aagagtatca aagtcaggag gaaaaaagat gactactttt aaagatggat
      721 ttttatgggg tggtgctgtt gctgctcatc aacttgaagg tggatggcaa gaaggtggca
      781 agggaattag tgttgctgat gttatgactg ctggtcgtca tggagtagct cgtgaaatta
      841 ctttgggagt tttagagggt aaatattatc caaatcatga ggcgatagat ttttatcatc
      901 gttataaaga agacatagca ctttttgctg aaatgggatt caagtgcttc cgtacctcta
      961 ttgcatggac acgtatcttt ccaaaaggtg atgagttaga gccgaatgaa gaaggattac
     1021 agttttatga taatcttttt gatgaatgct taaagaatgg tattgaacct gtcatcactc
     1081 tatctcattt tgaaatgcct tatcacttag tgaccgaata tggtggttgg aaaaatagga
     1141 aattgattga tttctttgct cgttttgcag aagtcgtatt taaacgttac aaagataagg
     1201 ttaaatattg gatgactttc aatgaaatca ataatcaagc gaattatcag gaagattttg
     1261 caccatttac taactcaggt attgtatatg aggaaggtga taatagagaa gcaattatgt
     1321 atcaagcagc acattacgaa ttagttgctt ctgcacgagc tgtaaaaatt ggtcatgaga
     1381 ttaatccaga ttttcaaata ggttgtatga ttgcgatgtg tccaatttat ccagttactt
     1441 gcaatcctaa ggatatctta atggcaatga aagctatgca gaagcgttat tattttgctg
     1501 atgtgcatgt tttaggtaaa tatcctgagc atattttcaa gtattgggaa cgaaaaggta
     1561 tttcagttga ttttactgac caggataaag aagatttact tggtgggact gtagattaca
     1621 ttggtttcag ttactatatg tcctttgcta tagactctca tcgtgaaaat aatccttatt
     1681 ttgattatct tgaaacagaa gatttagtga aaaataatta tgttaaggct tctgaatggg
     1741 agtggcaaat tgatccagaa ggtttacgtt atgcgttaaa ttggtttaca gaccactatc
     1801 acttaccact ctttattgtt gaaaatggtt ttggagctat agatcaagtt gcagcagatg
     1861 gtatggtaca tgatgattat agaattgaat atctaggtgc ccatattcgt gaaatgaaaa
     1921 aggctgtagt tgaagatggt gttgatttaa tgggttatac tccatgggga tgtattgatt
     1981 tggtttcagc tggtaccggt gaaatgcgga aacgttatgg ttttatttat gtagataaag
     2041 atgacaatgg gaagggaagt tataatcgtt ccccgaaaaa atcttttggc tggtataagg
     2101 aagttatttc atctaacggt gaatcagtag aatagtataa acaaactgag attattctca
     2161 gtttgtttag catattggga tgacatatga ttggaagtat tgcagcaatt ttaacaacat
     2221 ttgcattttt accacaagtt tttcgtatag ttaagacaaa ggacacagga tctattgctc
     2281 taggtatgta tgttatgcaa gttattggta ttgcattgtg gcttgctcat ggtattcgta
     2341 taggagactt gcctttgatt ttagcaaata gtgtttcatt tctactctca ggaataattt
     2401 tattttataa attgaagtat aaataatttt tttccatatc atttaggaaa atgagggaat
     2461 tgtcattgga aacgctttat tttataataa aaatagataa caaataagcc aacttagcac
     2521 agctttgatt ggatttaaga aaaggagaaa atattatggc aaaagcttta attatttgtg
     2581 cagcaggaat gtcttcatca cttatggcac agaaaacaac agagtttcta aaaggaaaag
     2641 ggaaagatat tgtagttgat gctattagtg ctactgaagg agggaaagct atcgcagcag
     2701 cagcttttga tttgtatctt gtcagccctc aaacaaaaat gtactttaag caatttgaag
     2761 aggctggttc taaagcagga aaaccagttg tacaaatacc tcctcaagcc tatattccta
     2821 ttccaatggg aattgaaaaa atggctaatt tgattcttga gaatatttga tgaacacatg
     2881 aaatgtcaat aaatatttag gttaagataa attgttttga gtttgatata aactgattta
     2941 agtgtataat atgcttcaat atatgaaaac atacgtttta ggagggaatg aatgtgttaa
     3001 acattaaaga gaaagatatc cttcaatttt taataaaaaa taaggaacgt tttgttacaa
     3061 gcaaagaact ggcagaatat ttatcctgtt cagatagaac tgtccgtaat gtactgaaat
     3121 taattgagaa gacaatgatt attcaaggag tccggttgat ttcaaaacaa ggtcaagggt
     3181 atcaaatatt ttttgagaat caaggcgctt accaggagtt tagacaaact tatgaactgg
     3241 aagaagacta tacgaaaact gcggtttcaa aaggtgatga tcgtttagta tttatcttaa
     3301 ataaattatt atttgagcaa gttccagttc tttttgatga tttagctgat gaactttacg
     3361 ttagccgttc aacattatct catgatttca gaaagatacg agtgatgtta tcagagtata
     3421 atttgtccat tgagagtagg gcgaataaag gagtttatgt ctcaggcgag gaacgtgata
     3481 aacgacgttt tatcataaat tatttcctag agaatcaatt ttttaaaaca atacattgct
     3541 atgtaaaatt taactttttt gatcaaactg ttccattaga agaatttgct agaattgttt
     3601 tggatgaatg ccaagaggcc aacctaaaac tatctgattt tgtactacag aatttagtag
     3661 ttcacatagc attgtctgtg attcgtttaa aatccggatt tgaaataaaa aatatagact
     3721 gtcagatgac tgatgatgca atagagagaa aggttgccca aagaattctt tctaaagtaa
     3781 gagaagtaac aaatcaggaa tttccagttc aggaaataga ctacattact ttgcatttgt
     3841 tagctaagag tcaacaatgt caaaaaaatc agaagaatat ttctgaagaa gttttaaaaa
     3901 aaatctttat ttaaaacatt tcagaattta ggattagatg atatgtataa cttttcttca
     3961 gatttccaac taattgaagg attgataact catctaatga cactacaagt acgtttagaa
     4021 agccggatta ccttaaataa ccctttggta gatgaaatta aacagaatta tagtgatata
     4081 ttctttatga ctagagaaat tcttgcaaat atggacaagt tcttggagtg gacaatatca
     4141 gatgatgaag tagcatatgt aagtcttcac tttttagctg ctatggaacg tagcaaagag
     4201 agtactaagt ttaatattct tgctatttgt gcaacaggat ttggtgcagc ccaaatgtta
     4261 agaaatcgtt tggaaacgga gtttgggaag cgagtagaag ttgttgatgt aataggctac
     4321 tatgaattga atcaagaaaa acttaaagga atagatttta tagtgtcagc tgttgattta
     4381 tcaaatctat attttcaaat cccagttttt aaagttagtg tgtttcttaa aagtgatgag
     4441 atggaaatga ttagaaaagc tatggatcag atgcaagttt ctagttatgt acaatcatca
     4501 aagattaaca aatttgaaaa caacggcttt agacagtatt ttagtaaaga aaatttttta
     4561 atatgtactg aatcagacaa ggtaaattta cttgaaaaga tggttgaggg tttatctgtt
     4621 ggtgaatcaa atgagtttga acaatcttta ctttatggaa ttaaacagcg cgaagaatta
     4681 agttcagttg ttttttctga aaaaattgca gttccgcatc ctattcagcc ctttggtaca
     4741 gagggaaagg tttcggttgc aatttgtaaa gattcgctac tctgggataa tcaaagttca
     4801 catgtccagc tagtatttct tctatctcca tcaatatatg ggaacgaagg tttggcaact
     4861 gtgactaaaa agatagtctc tctgacagag aatgatgaat tgcaaaatca gctaatatct
     4921 tgcaataact ttgaagattt tattaacata tttgagaaga taaaatagga ggttcatatg
     4981 aatcaagagg aactgcaggt tgcagcattt gaaattatcc tgcattcggg aaatgcaagg
     5041 tcagaaatac atgaagcatt tgcaaaaatg agagaaggta gttttgatga tgcagaaagt
     5101 aaattaaatc aatcaaatga gataattctt gaagcgcatc atgcacaaac caaactcttg
     5161 caagaatacg caagtggagt ggaaattaaa attgaaatta tcatggtaca tgctcaagat
     5221 catttaatga ccactatgac attattagaa gtagcaaagg aaatgttagc tctttataag
     5281 aaagttaact aaatatgtgt tgttatataa ggaggaaatg atatggataa aaaagaacga
     5341 caaaagattg aacaacaacg tcgagagatg gctctaacta atactttttt taatcgatat
     5401 cttcttctac gttattcaat agcactcttc ttttttggga atatttattg gcttttgagt
     5461 cagtttatta gtccctcgcc tattattatt ttccccatta tgctcatagt attttctatt
     5521 ttagcaactg ttgaacaatt taaactctat ggaaatagga aagaaaagtt gggaataaca
     5581 ctaatgtttg ttagaataca aatgcttatt tcaataggat tacttgtttt aacttggaca
     5641 agttggttta agaatctttt tccgattttt gaaaataacc aagtagcacg tttatttgtt
     5701 tttgtagttc ttctattagg tttagctctg agtttgttag acattagaag aattaaaaaa
     5761 atttataaac gaacagataa ggcttatcaa caatttgtcc aattggaaaa gaactcactt
     5821 agtttataat cctgatctag tataatttgt atttgaaacc agtctttaga aagtaaaaat
     5881 tattatgttt tattaaggag gtctatttat ggatcaacaa aacgggttgt ttggttttct
     5941 tgaaaaccat gttatgggac caatgggcaa acttgctcag tttaaagtag tgcgtgctat
     6001 cacggctgca ggtatggctg ctgtaccatt tactattgta ggatcaatgt ttttggtatt
     6061 cagtattttg ccacaagctt tctcattttg gccaattgtg gcagatattt tctctgcttc
     6121 atttgataaa ttcacatcac tttacatggt tgcaaactat gcgactatgg gttctctatc
     6181 tctttatttc gttctatcac ttgcatatga attgacaaaa atttatgcag aggaagaaga
     6241 actcaatatg aatcctctta atggtgcctt gcttgccttg atggcttttg tcatgacagt
     6301 accgcaaatc atttttgatg gtggaatgat gaagactgtg acaagtctaa aagaaggtgc
     6361 agtaattgca gatggatggg caatgggaaa tggagtcgca cgttttggga caacagggat
     6421 ttttaccgca atcattatgg caattgtgac tgttcttatt tatcgtatgt gtgttaaaca
     6481 taattgggtt attaaaatgc ctgaagctgt tccagaagga gtttctcgtg gatttaccgc
     6541 tttggttccg ggatttgttg ttgcatttgt tgttatcttt atcaacggtc ttcttgtagc
     6601 aatgggaaca gatattttta aagtcattgc aattccattt ggttttgtat ccaatctgac
     6661 taattcgtgg attggtttaa tgattattta tctattgact caactacttt ggattgtagg
     6721 tatccacggt gcgaacattg tttttgcatt tgttagtcca attgctcttg ctaacatggc
     6781 tgaaaatgct gctggcgggc acttcgctgt tgcaggtgaa ttttctaata tgtttgtaat
     6841 tgcaggtggt tctggtgcaa ctttaggact atgtttatat attgcttttg cctctaaatc
     6901 tgaacagctt aaagcaatag gacgagcatc tgtagttcca gccttattta atattaatga
     6961 accattaatt tttggattac ctattatcta taatccagcc ttggctatac catttatttt
     7021 agcaccaatg gttactgcta ctatttatta cgtagcgaat tctctaaact ttattaagcc
     7081 aattatcgca caggttccat ggccaactcc agtagggatt ggagctttct tagggacagc
     7141 agatcttcga gctgtattag ttgctctagt atgtgcattt gcagcattcc tagtctatct
     7201 tccattcatc cgtgtatatg atcaaaaatt ggtgaaagaa gagcaaggta tctaataagt
     7261 aaaaaagtat actcgatgat agaatccata tagtttaaat aatgagtgtt aacattagca
     7321 gtgaagagat ctttttaaga tattcttctc tgctttttca ttttattttt ttgctatgta
     7381 gggtatgaag caaaatagaa agtagttcga atagttgata aacagggaac tgctgttatt
     7441 taaaaaaaca ataaagtaaa gtatgttatc gtagaatacg atacaatagt aaaaaagcaa
     7501 aaagaatgcg ttttatattt gggtttgagg cttataaaat aggataagcg tgctgaaaac
     7561 ttagatatga caaacaaaat aaaattttta aaagctacag agaaacatgg tataatgtat
     7621 ctaaaggagg tagcatatgt ccttagatat agataaagaa aagatgacaa tcatgggaat
     7681 agcttttgaa aaccgatccg tttttaagag tgtttggtat gctttaagta caaatatgat
     7741 tgaaggatgg cgacctacgg ttagtgatgt tgaaaaatta cgagatgaag ctcttgctct
     7801 ggggatgact taatgaagcg caactgttat gaatcttatg actatgttga tccggataat
     7861 ttatataccg atccgggttc ttcagttcta agaaataagc aggaaggaaa aaagcacgtg
     7921 agcttgaata tcgtatgatt gctagtaaga gtttgaaatt atttatcaat cctatcttag
     7981 ttaatagttt aaaagtagtt tgtttcacaa ctgcataagc ttagaaaagt tgaaaagtga
     8041 taactcttta ataaactctt ggtttgttaa aagatatttt gtccactaca ttttttcaat
     8101 tgactattat ttgtcataga tataacagat agaacattgc attcagaata atgaaaaacg
     8161 catcaaaaat ggtgcgttct gtttttatgc taccataaaa ggaggaaaac aaattgaaaa
     8221 tttttaaggg agagttttat cgaatctctg tattaacaga caagctagta aggttagaat
     8281 actctcgaac tggaaatttt gaggatagaa cgacacaact tatctataat agagattttg
     8341 gccaagtttc gttagattat atcgagacat caaatgtact agatattatg acggactatt
     8401 ttcatctgca ctttaataaa ggagaattta acgccgaaaa tttatttata gaattaaaag
     8461 gaaattttgc cgtatatggt agtcgctggt attttggtga atctattgaa acgttaaaag
     8521 gaacagctcg gactctggat aaggcagatg gagcaatctc gttagaagat ggaattatta
     8581 gccgaaatgg tatagcctta ttggatgatt ctcaaggatt tatttgggat gaacaatctg
     8641 gttatattga gagagaaaat caaattgacc tgtatttctt tgcctatggg catgattata
     8701 gaggagcaat cagagacttt taccatttga ctggttcaac acccttgttg ccaagatatg
     8761 ctttaggcaa ttggtggagt agatattggc cttatacgtc ggatgaatac ttggatttaa
     8821 tagacagatt tgaaacagag aaaattccat tatctatcgg tgtgttagat atggattggc
     8881 atataactga cattccagct cgttttggaa gtggctggac aggatatagt tggaataaaa
     8941 acttaatacc taatccagaa cagttattgc aacaacttca tgatagaaag ttaaaactct
     9001 ctttaaatgt ccatcctgct gatggtatac gggcttatga agaagcttat cctcaagtcg
     9061 ccaaacgatt agggttaaat gtagaactag aagaacctgc catttttgat ttttttaatc
     9121 cctcttttag ggaagcctac tttaaagatg ttcattatga gctagaaaag cagggagtag
     9181 atttttggtg gattgactgg caacaaggga ctcaaggcat attggatcca ctatggcttt
     9241 taaaccatta tcattatcag gatagttgta aaaatgcaga aggtggtttg attttatcaa
     9301 gatatgcagg tcctggtagc caccgctacc ctgttggttt ttcaggggac actattatta
     9361 gttggaattc cttaagattt caaccttatt ttacagcgac agcatctaat atcggttata
     9421 gttggtggag ccatgatatc ggtgggcaca tgctggggga ttatgacgaa gagctgcaaa
     9481 ctagatggct acagtttggt gtttttagtc cgatcactcg attacatagt tctagaagtc
     9541 cttttaatag taaagaacct tggttttttt cagaaacaac atctaagatt atgaagaaat
     9601 accttcgttt gagacatcag atgattccct atctatatac catgaatgta aagacacacg
     9661 aggaaggtgc cccattaatc agtccaatct attatttcta cccagagaat gatgagagct
     9721 ataatgttcc aaaccaatac ttttttggaa cagaactaat ggtggctccc attgtagaaa
     9781 agatggactt ggcattccaa tctgcaaaag tggatgtatg gttccctgaa ggtgaatggt
     9841 atgacttctt ttcagagaaa aaatatacag gtggtgtgaa gttgagtgtt tatagagaca
     9901 tttcgactat acctgtgttt gcaaaaagtg gtgcgatcat tcccttggtt ggttctgaga
     9961 tagatatggg tgttgattta cctgaagttg tagattggta tgtattccca ggcaaacaac
    10021 attcttttga aatgcttgaa gatcaaaatg gtcaaagata taaaacaaga ttatcaatcg
    10081 attgggaaat ggggatggta gagttaacat tacaaggaga ttctagtatc gttccaagca
    10141 atagaaggca tagaattcat tttaaaggaa cgaatgtgtc tataattgaa ttaccaaata
    10201 agaatgatac agctagattt gaatgtaaag ataataaaac aatatcttta aatgatgaag
    10261 tttttagact actaaagaca gcttctcttc catatgaatt aaaagataga ttgttaaatc
    10321 aattcatcaa tgcgaaaaac tctcatgact taatgaatat cttgcatcat caggataagg
    10381 aattgagagg gcgtttgttg gaaatgatat ttactagcca aaactaattg atataattag
    10441 aaagtcattt gtttagtgta tatgaagatt ctgtatggta ttcgttatca ctggtcacat
    10501 tgaaaatgtg aaataagcac ctacaacata gactttacaa cacttcatgt ttcatatcat
    10561 ggggtgtttt tctatttaag tcaaagccaa tcaaaaaatc tcactattca tcaggttaaa
    10621 ggaaacctaa tcatagtgag attgtgaatt atagtagagt ttgtatcgcc tcttcaattt
    10681 gttttgggtc tgtttttgaa gaaaagcgtt caaagacttg cccatctcga ccgatgagaa
    10741 acttagcgaa attccattcg actcgttttc ctagtgggcc ggatttctgg tcttttaacc
    10801 agacatagag agggtctgct tccttaccgt tgaccttaat cttggcaaaa cgtgggaagg
    10861 tggtttgaaa atgtaggcta cagaaggcgt tgatttcctc tgcgctgccg ggtgcttgtc
    10921 ccataaactg attgcaaggg aaatccaata tttcaaagcc ctgatcttga tagcgttcat
    10981 agagttcttg aagtccctgg tactggggcg ttaaaccaca tccagtagca gtgttgacaa
    11041 tcaagagaac tttgccacga tagctatcca agggagttgc ttggttgttt tggttcaaaa
    11101 cggaaaaatc ataaagtgaa gtcatgaggg cctcttttct ttttctacat tgtaacagtt
    11161 tttacttttt tcgtcgagtc ggatggaaga tattgttgaa gaataagccc tcaatatgat
    11221 agaaaccgtt tacaaataac tttaaaaatg gtataattta attaaaccgg tttacttagt
    11281 tgctataaat ctctaatttg agatttagtt cctattgatt ttacaatatg tttattggag
    11341 tgtatacatg caaacaaaaa caaagaagct cattgtgagt ttgtcttcac ttgttttatc
    11401 aggattttta ttaaaccatt atatgacagt tggagcggaa gaaacgacta cgaataccat
    11461 tcagcaaagc cagaaggaag ttcagtatca gcaaagggat acaaaaaatt tagttgaaaa
    11521 tggtgatttt ggtcagacgg aggacggaag cagtccgtgg acaggaagca aagctcaggg
    11581 gtggtcagct tgggtagacc agaagaatag ttctgcagat gcctcaactc gagtcattga
    11641 ggctaaggat ggggctatca ctatctcaag ccatgagaaa ttaagggcag cgcttcaccg
    11701 tatggttcct attgaagtta agaaaaagta taaactgcgt ttcaagatta aaacagataa
    11761 taaaatcggg attgccaaag ttcgtatcat tgaggaaagt ggtaaggaca agcgattgtg
    11821 gaattctgca acgacgtcag gaacaaagga ctggcagacc attgaagcag actatagccc
    11881 gactttagat gttgataaaa tcaagctgga gttattctat gaaacaggaa ctgggactgt
    11941 ttcctttaag gatattgagc tggtagaggt agcagcccag ctttctgagg attctcaaac
    12001 agataaacag cttgaggaaa agattgattt accaattgga aaaaaacatg ttttttctct
    12061 tgcggactat acttataagg tagaaaatcc tgacgttgct tcagtcaaaa atggaatttt
    12121 agaacctctt aaggaaggga caaccaatgt cattgtcagt aaagatggca aggaagtgaa
    12181 aaagattcct ttgaagattc tagcctctgt taaggataca tacacagacc gtttggatga
    12241 ctggaatggc atcatcgctg ggaatcaata ctatgattct aaaaatgaac agatggccaa
    12301 attaaaccag gaattggaag gaaaggtagc tgatagccta tccagtattt caagtcaggc
    12361 ggaccgcacc tatttgtggg aaaaattttc aaattataaa acgtctgcaa atctgactgc
    12421 cacttatcgg aaattggagg agatggccaa gcaagtgacc aatccttctt ctcgttatta
    12481 tcaagatgaa actgtcgttc gaacagtcag ggattccatg gaatggatgc ataaacatgt
    12541 ctacaatagt gaaaagagca ttgttgggaa ctggtgggat tatgaaatcg gtacacctcg
    12601 tgccatcaac aataccttgt ctctgatgaa agaatacttc tctgatgagg aaattaaaaa
    12661 atatacagat gtgattgaaa aatttgtacc agatcccgaa catttccgaa agacgactga
    12721 taacccattt aaggctctag gtggaaactt agttgatatg ggaagagtaa aagtaatagc
    12781 tggtttactg cgtaaggatg atcaagaaat ttcttctacc attcgctcga ttgagcaagt
    12841 gttcaagttg gtagaccaag gtgaaggttt ttatcaagat ggatcctata tcgaccacac
    12901 caatgttgcc tatacgggtg cttatgggaa tgttttgatt gatggcctgt ctcaactgtt
    12961 gccagtcatt caaaagacca agagtccaat cgataaagat aaaatgcaaa ccatgtacca
    13021 ctggattgat aaatcgtttg ctcctttgct ggtgaatgga gagctgatgg atatgagtcg
    13081 tggacgctcg atcagtcgtg caaatagcga ggggcacgtg gccgcagtag aagtactaag
    13141 agggattcac cgaatagcgg atatgtctga aggagaaacc aaacaacgtt tgcagagtct
    13201 tgtgaagacc attgttcaat cggatagtta ttatgatgtc tttaagaatt tgaagactta
    13261 taaggatatc agtttgatgc aatccttgtt aagtgatgca ggagtcgcaa gtgttccaag
    13321 aacaagttac ctatctgcct ttaacaagat ggataaaaca gccatgtaca atgcagagaa
    13381 agggtttgga tttggcttgt cactcttttc cagtcgtacc ttgaattacg aacacatgaa
    13441 caaggaaaat aaacgtggtt ggtatacgag tgatgggatg ttctatcttt acaatggcga
    13501 tttgagtcac tatagcgatg gctactggcc aacagttaat ccatataaga tgcctggtac
    13561 aacagagacg gatgctaaga gagcggatag cgatacaggt aaagttttac cgtctgcttt
    13621 cgttggaacg agcaaactag atgatgccaa tgcgacagca accatggatt tcaccaactg
    13681 gaatcaaaca ttgactgctc ataagagctg gtttatgcta aaggataaga ttgccttttt
    13741 aggaagcaat atccaaaaca cttcaacaga tactgctgca actacaattg accagagaaa
    13801 actggaatca agtaatccat ataaagtcta tgtcaatgat aaagaagcct cccttacaga
    13861 acaagaaaag gattatcctg aaacccaaag tgtcttttta gaatcgtccg attcgaaaaa
    13921 gaatattggt tactttttct ttaagaagag ttcaatcagt atgagtaagg ctttgcaaaa
    13981 gggagcctgg aaggatatca atgaaggaca gtcagacaag gaagttgaaa atgaatttct
    14041 tactattagt caggctcata agcaaaatgg agattcttat ggctatatgc tcattcctaa
    14101 cgtggatcgt gccaccttca atcaaatgat aaaagagtta gaaagtagcc tcatcgaaaa
    14161 taacgaaacc cttcagtctg tttatgatgc caaacaagga gtttggggca ttgtgaaata
    14221 tgatgattct gtctctacta tttccaacca attccaagtt ttgaaacgtg gagtctatac
    14281 cattcgaaaa gaaggggatg aatataagat tgcctactat aatcctgaaa cccaggaatc
    14341 agctccagat caggaagtct ttaaaaagct agagcaagca gctcagccac aagtacagaa
    14401 ttcaaaagaa aaggaaaaat ctgaagaaga aaagaaccat tcggatcaaa agaatctccc
    14461 tcagacagga gaaggtcagt caatcttggc aagtctaggg ttcttgctac ttggggcgtt
    14521 ttatttattc cgtagaggaa agaacaacta atttgttcat catctagatg aattacatga
    14581 aactgtggaa aatagaaaaa atccgaagaa ggccaaatat cttcggattt ttcttttaaa
    14641 aagggataag ttgatactta tcctttttta cttcattatg tgactatagc gttttgaaac
    14701 tagaatagga cgtcataact gctaaaagat ttctataaat tcatttgatt ttcctaatca
    14761 atttgttcgt atcctatttc actccactat attagtccgt ctcgctccgt gaggtgcgag
    14821 acaaaacaac cacccgctat gcgggtgcgc gtcgaaggct ataccaaaaa actccaaacg
    14881 cgatacaata aaggtgttca atccaattgt aaagcgaaag gagaaaaaat atggcacaaa
    14941 agactcatag tttatcatac acaaagtgga tgtgttctat catattgtgt tcacccctaa
    15001 gtatagacga aaagtcatct ataatcaata tagaagtagt ttaggcgaaa tatttcatcg
    15061 cttgtgtagt tataaaggtg ttgaaatgat cgagggtcac ttaatgccag accatgtaca
    15121 catgttagtc agtattccac taaggctaag tgtttcgagt ttcatggggt atttaaaagg
    15181 caaaagtgca ctcatgatgt ttgacaaaca cgccaatctc aagtacaagt ttgggaatcg
    15241 gcatttctgg gcggaaggtt attatgtaag tacagtaggg cttaataaag ccacacttaa
    15301 gaaatatagt caagattaaa gaaattatcg agtggatgat ttcttcacga gtatgaaaat
    15361 ttgagaacga gtaaagtatg atatatagta aaatgaaata agaacaggac aaaatcgatc
    15421 aggacagtca aatcgatttt taacaatgtt ttagaagtag aggtgtacta ttccagtttc
    15481 aatctactat agcactagat aaattgagtg taaaagaata tgaggatccc tttagggata
    15541 gtggtaagta ataccaaagt ctcttaaaga ggcaagtgac gagtcaagag caataaggct
    15601 tgaacaacgt gaaagccagc gtctttaggc gctggctgat gatttgggct tatagctctg
    15661 agataaacca cccgttagac gggtagttat gattttatct gagtgtaaca tactgttggg
    15721 caatctcgct gatgccgtca aagttgcctt gggaagcgag tttattgagt tcgccaccaa
    15781 ttccaacggc atctgcacca gcagcgaacc attgagggat gttgtttaga ccgactcctc
    15841 cggttaccat tacggaaact tgtgggatcg gtgccttgac tgcagagata tatgctggac
    15901 tgagagcact acctgggaag agtttgatga tttcactacc ggcttcaagt gcagtcgtga
    15961 tctctgtgag ggtaatacag cctggaatgt acggtgtgct gtagagattg cacattttcg
    16021 cagtttcagc atggaaagat ggagaaacaa cgtaatttgc tccggctaga atggcatctc
    16081 tagcagttac ggcatcaagc acagtacctg caccgataca aacactctga tcgtcctgat
    16141 acaagtctac aagttccttg atgatttgtc ctgcatactg attggtatag gcgatttcaa
    16201 tagctttgat accgcccttg atacaagcaa tcgaggcttg cagtccttct ttctttgtat
    16261 ttcctcgaat gacagcgaca attttctgtt tttttagttc aataatcgta tctgatttgg
    16321 tcatgtaatt ctcctaacga atgatatctt gtgcatttgc cagtaaattt tcaatactag
    16381 ttgcggaagt ggagagatgg tctcctggaa gagtgcattt gagagttgcg ctcgcaactg
    16441 caaagtcaat ggtagttttt agggaggaat gatggagtag ttggtaaagg gcaccagata
    16501 taaaggcatc cccgctacca attcgttgat agactgcagt ttttagttgg acagactctt
    16561 caaatcgttc ttccagagca taggcttgat agacattttt gtcttgctca tcactagagc
    16621 ggagggtatg gaaaatggcc ttgaaaccat aggcttcttt taaaagtcgc atgcgatttt
    16681 ccacctcttc taggctagca ctgtctcttg gaaacatctc tagattttgg tcatcaatca
    16741 tgagaggatc aataccgaag caatagtcag taaaacgtgc aaacttagaa aattcatact
    16801 tggcttctag gactgaaatc atctttgttc tcagattgag atccattgaa acgacaattc
    16861 ctcggcgctt ggcttcttcc aagagtagga gaaggatcgc acggacctct tgaccgatag
    16921 ctatggtgat tccactaaaa tgaaaatggc taatcccctg aaagagagaa tccatatcta
    16981 gcatgtttgg ccgaatctgg ctgatactcg tatgcttacg atcgtagaaa acttcacttt
    17041 gacgacaacc aaagccgttc tccaaatagt agaggccgat tcgatcgcca agccgacaga
    17101 ttgaactggt atcgatttgg tgctgtttca agaatgtgag aaaacgatct ccaatctcgt
    17161 tggcagggag tgcggtaaag actttcgttg agatacccag ggcttgcaaa ttacaagcga
    17221 tgttaatttc tgatccgcca aaataagtcg aactggcaac atgatcgccg atactggtgg
    17281 catctaatgg tgagattcga attaatggtt cgccaaacag taatattttc gtcatccatt
    17341 agttcctttc tggtttagaa tagctttact tggctaatac ttctttcaaa taagcagcga
    17401 cttcatcatc ttggcagttt tcaaagaagt attcttggaa gtatttgcca gagatggtgt
    17461 ctttgaggaa gtcttggtcg attgttttaa ggatggtcat caaatcattg tgggtgattt
    17521 gtttcacctc gtttaagata cgagcgttac gttgttcagg gattacacgt tctcttgggt
    17581 agccaccgcc catttcttca gcaaataagc gttcaaacat caatttgagg gtcagttctg
    17641 ccccccagcc aaatcctttg gcataaggga tagacaaggc gttaccacca ttgatttgag
    17701 aataaaggta agcgtcagtt gggtccactg ctagaccaca gacaacacca gggaagctgt
    17761 ttaaagcaag catagcccct acacccgtac cacagccggt aacaacaaag tcaactgcct
    17821 ttgtatttaa aaggatggca gccattagtc cgttctgcac ataagttaat tgactttctc
    17881 cttcttctcc acgcatacca tagttaaata attggtagtc ttttttatct gtcgcttctt
    17941 ttagactatc gtaaataatg tgattcttgc tagcttgact attttcattg attaatgcga
    18001 ttttcataag atcttctttc tatttttact caggttgttt tccgatgtag gctaagatac
    18061 cgccatctac atataggatg tggccattga caaaattgct ggcatcacta gcgagaaaga
    18121 cagcagggcc catcaaatct tcaggatttc cccaacgtgc agcaggtgtt tttgcaatga
    18181 tgaactggtc aaatgggtgg cgagaaccat cttcttgcaa ctcacgaaga ggtgctgttt
    18241 gaggagtggc aatataaccc ggtccaattc cgttacattg gatattggct ccaccgtatt
    18301 cagacgcaat gttgcgggtc aacattttca agcccccttt agcagcagca taagcgctaa
    18361 ctgtttcacg tcccagttcg ctcatcatcg aacaaatatt gataatcttt ccatgccctt
    18421 tctttatcat agaaggaata actgcctttg aaacgataaa tggtgcgttt aagtcaatat
    18481 cgatgacctt acggaaatca gcggcgctca tttcgcacat tggaactcgg cggataatac
    18541 cagcgttatt aacgaggatg tcaatgacac caacctcttg ttcgatttgc ttgaccatgg
    18601 cttggatacc gtcctcgtct gtcacgtcac agacatatcc atgggcttcg atgccaactt
    18661 cacgataagc ttcaatccct ttattgacca gatcttgatt gatatcgtta aagacaatag
    18721 tagcgccggc ttcagcgtag gatttggcaa tagcaaatcc aattccataa gaagcgccgg
    18781 tgatgagagc aatttttcct tttaaagaaa actgctcaat tgagaatgat gtatttgtca
    18841 tttgatactt cctttcaaat ttgttaagac ttctct
//
LOCUS       DAVIME010000041        18448 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVIME010000041 DAVIME010000000
VERSION     DAVIME010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18448
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.041"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..1077
                     /gene="dnaN"
                     /locus_tag="VV588_001564"
     CDS             <1..1077
                     /gene="dnaN"
                     /locus_tag="VV588_001564"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU7083880.1"
                     /translation="AISSKNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNED
                     AGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQ
                     YPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVAT
                     DSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENI
                     SFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKD
                     GVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAV
                     RPFTLVPADTDEDFMQLITPVRTN"
     gene            1142..1336
                     /locus_tag="VV588_001565"
     CDS             1142..1336
                     /locus_tag="VV588_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU7083881.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1420..2535
                     /gene="ychF"
                     /locus_tag="VV588_001566"
     CDS             1420..2535
                     /gene="ychF"
                     /locus_tag="VV588_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU7083882.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2606..3175
                     /locus_tag="VV588_001567"
     CDS             2606..3175
                     /locus_tag="VV588_001567"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU7083883.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3176..6685
                     /gene="mfd"
                     /locus_tag="VV588_001568"
     CDS             3176..6685
                     /gene="mfd"
                     /locus_tag="VV588_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU7083884.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            6753..7019
                     /locus_tag="VV588_001569"
     CDS             6753..7019
                     /locus_tag="VV588_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU7083885.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7012..7380
                     /locus_tag="VV588_001570"
     CDS             7012..7380
                     /locus_tag="VV588_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU7083886.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7500..8768
                     /locus_tag="VV588_001571"
     CDS             7500..8768
                     /locus_tag="VV588_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU7083887.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8765..10042
                     /gene="tilS"
                     /locus_tag="VV588_001572"
     CDS             8765..10042
                     /gene="tilS"
                     /locus_tag="VV588_001572"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU7083888.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPKLEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKTQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10046..10588
                     /gene="hpt"
                     /locus_tag="VV588_001573"
     CDS             10046..10588
                     /gene="hpt"
                     /locus_tag="VV588_001573"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU7083889.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEVDYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10604..12562
                     /gene="ftsH"
                     /locus_tag="VV588_001574"
     CDS             10604..12562
                     /gene="ftsH"
                     /locus_tag="VV588_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU7083890.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNKARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            12684..13163
                     /locus_tag="VV588_001575"
     CDS             12684..13163
                     /locus_tag="VV588_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU7083891.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            13257..13328
                     /locus_tag="VV588_001576"
     tRNA            13257..13328
                     /locus_tag="VV588_001576"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13290..13292,aa:Glu,seq:ttc)
     gene            13581..15126
                     /locus_tag="VV588_001577"
     rRNA            13581..15126
                     /locus_tag="VV588_001577"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            15178..15250
                     /locus_tag="VV588_001578"
     tRNA            15178..15250
                     /locus_tag="VV588_001578"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15211..15213,aa:Ala,seq:tgc)
     gene            15375..18276
                     /locus_tag="VV588_001579"
     rRNA            15375..18276
                     /locus_tag="VV588_001579"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            18353..>18448
                     /gene="rrf"
                     /locus_tag="VV588_001580"
     rRNA            18353..>18448
                     /gene="rrf"
                     /locus_tag="VV588_001580"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6055 a         3034 c         4239 g         5120 t
ORIGIN      
        1 gctattagtt ctaaaaatgc cattcctatt ttatcaacag taaaaattga cgtgaccaat
       61 gaaggtatta ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt tatttctcaa
      121 aaaaatgaag atgctggttt gttaattact tctttaggtt cgatccttct tgaagcttct
      181 ttctttatca atgtagtatc tagtttacct gatgtaactc ttgattttaa agaaattgaa
      241 caaaatcaaa ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg aaaagatagc
      301 gaacaatatc cacgaatcca agaaatttca gcaagcactc ctttaatact tgaaacaaaa
      361 ttactcaaga aaattattaa tgaaacagcc tttgctgcaa gtacacaaga gagtcgtccg
      421 attttaacag gtgtccactt cgtattgagt caacacaaag agttaaaaac agttgcaaca
      481 gactctcatc gcctaagcca gaaaaaattg actcttgaaa aaaatagtga tgattttgat
      541 gtcgtaattc ctagccgttc tctacgcgaa ttttcagcgg tatttacaga tgatatcgaa
      601 actgtagaga ttttctttgc caataatcaa atcctcttta gaagcgaaaa tattagcttc
      661 tatactcgtc tcctagaagg aaactatcct gatacagatc gcttgattcc aacagacttt
      721 aacactacta ttacttttaa tgtggtaaac ttacgccagt caatggagcg tgcccgtctt
      781 ttatcaagtg cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg ggttgttagc
      841 gcccatgttc actctccaga agttggtaaa gtaaacgaag aaatcgatac tgatcaggtt
      901 actggtgaag atttgaccat tagtttcaac ccaacttact tgattgattc tcttaaagct
      961 ttaaatagcg aaaaggtgac tattagcttt atctcagctg ttcgtccatt tactcttgtg
     1021 ccagcagata ctgacgaaga cttcatgcag ctcattacac cagttcgtac aaattaagtg
     1081 aaagaggttg agcctggctc gcctctttta tgatataatc gaaaaagaaa aggagagtag
     1141 tatgtatcaa gttggaaatt ttgttgagat gaaaaaatca cacgcttgta caatcaagtc
     1201 gactggtaaa aaggctaatc gttgggaaat tacacgtgta ggagcagata tcaaaataaa
     1261 atgcagtaat tgtgagcatg ttgtcatgat ggggcgatat gattttgagc gaaaaatgaa
     1321 taaaattatt gactgagaac ccttagttag agggttagca ctttatccct ttttgtgtta
     1381 taatattagg gattgaaatg aaaacggaga atgagaaata tggctttgac agcaggtatc
     1441 gttggtttgc caaacgttgg taaatcaaca ctatttaatg caattacaaa agcaggagca
     1501 gaggcagcaa actacccatt tgcgactatt gatccaaatg ttggaatggt ggaagttcca
     1561 gatgaacgcc tacaaaaact aactgaaatg ataactccta aaaagacagt tcccacaaca
     1621 tttgaattta cggatattgc agggattgta aaaggagctt caaaaggaga agggctaggg
     1681 aataaattct tggccaatat tcgtgaagta gatgcgattg ttcacgtagt tcgtgctttt
     1741 gatgatgaaa atgtgatgcg cgagcaagga cgtgaagacg cctttgtgga tccacttgca
     1801 gatattgaca ccattaacct agaattgatt cttgcagact tagaatcagt caataaacga
     1861 tatgcgcgtg tagaaaagat ggcacgtacg caaaaagata aagaatcagt agcagaattc
     1921 aatgttcttc aaaagattaa accagtccta gaagacggga aatcagctcg taccattgaa
     1981 tttacagatg aggaacaaaa ggttgtcaaa ggtcttttcc ttttgacgac taaaccagtt
     2041 ctttatgtag ctaatgtgga cgaggatgtg gtttcagaac ctgactctat cgactatgtc
     2101 aaacaaattc gtgaatttgc agcgacagaa aatgctgaag tagtcgttat ttctgcgcgt
     2161 gctgaggaag aaatttctga attggatgat gaagataaaa aagagtttct tgaagccatt
     2221 ggtttgatag aatcaggtgt agataagttg acgcgtgcag cttaccactt gcttggattg
     2281 ggaacttact tcacagctgg tgaaaaagaa gttcgcgctt ggactttcaa acgtggtatg
     2341 aaggctcctc aagcagctgg tattatccac tcagactttg aaaaaggctt tattcgtgca
     2401 gtaaccatgt catatgagga tctagtgaaa tacgaatctg aaaaggccgt aaaagaagct
     2461 ggacgcttgc gtgaagaagg aaaagaatat atcgttcaag atggcgatat catggaattc
     2521 cgctttaatg tctaaaaatt aataaatggt gtcaattagg ttggaaaaaa attccaaccc
     2581 ttttggcttt tgaaaggaaa aataaatgac caaattactt gtaggcttgg gaaatccagg
     2641 ggataaatat tttgaaacaa aacacaatgt tggttttatg ttgattgatc aactagcgaa
     2701 gaaacagaat gtcactttta cacacgataa gatatttaaa gctgacctag catccttttt
     2761 cctaaatgga gaaaaaattt atctggttaa accaacgacc tttatgaatg aaagtggaaa
     2821 agcagttcat gctttattaa cttactatgg tttggatatt gacgatttac ttatcattta
     2881 cgatgatctt gacatggaag ttgggaaaat tcgtttaaga gcaaaaggct cagcaggtgg
     2941 tcataatggt atcaagtcta ttattcaaca tataggaact caggtcttta accgtgttaa
     3001 gattggaatt ggaagaccta aaaatggtat gtcagttgtt catcatgttt tgagtaagtt
     3061 tgacagggat gattatatcg gtattttaca gtctgttgac aaagttgacg attctgtaaa
     3121 ctactattta caagagaaaa attttgagaa aacaatgcag aggtataacg gataaatggt
     3181 gaccttatta gatttattct cagaaaatga tcagattaaa aaatggcatc aaaatttaac
     3241 tgataagaaa agacaactaa tacttggttt atcaacatct actaaggctc ttgcaattgc
     3301 aagcagttta gaaaaagaag ataggattgt gttattgacg tcaacttatg gagaagcaga
     3361 aggacttgtt agtgatctta tatctatctt gggtgaggaa ctcgtctatc catttttggt
     3421 agatgatgct cctatggtgg agtttttgat gtcttcacag gaaaaaatta tttcacgggt
     3481 tgaagccttg cgttttttga ctgattcatc taagaaaggg attttagttt gtaatatcgc
     3541 agcaagtcga ttgattttac cgtctcccaa tgcattcaaa gatagtattg taaaaatctc
     3601 agttggtgaa gaatatgatc aacacgcgtt tatccatcag ttaaaggaaa atggctatcg
     3661 aaaagttact caagtacaaa ctcagggcga atttagtctt cgaggagata ttttagatat
     3721 ttttgaaata tcccagttag aaccttgtcg aattgagttt tttggtgatg aaattgatgg
     3781 tatcaggtca tttgaagtag aaacacaatt atcgaaagaa aataagacag aactcactat
     3841 ctttccagct agtgatatgc ttttgagaga aaaggattat caacgaggac agtcagcttt
     3901 agaaaaacaa atttcaaaaa ctttatcacc tattttgaaa tcatacctag aagaaattct
     3961 ttcaagtttt caccaaaaac aaagtcatgc agactctcgg aagtttttat ctttgtgcta
     4021 tgataagaca tggactgtct ttgattatat tgaaaaagat actccaatat tctttgatga
     4081 ttatcaaaaa ttgatgaatc agtatgaagt ctttgaaaga gacttagcgc agtactttac
     4141 agaagaatta cagaatagta aagcattttc tgatatgcag tatttttctg atattgaaca
     4201 aatctataaa aaacaaagtc cagtgacctt tttctctaat cttcaaaagg gtttaggaaa
     4261 tctcaaattt gacaaaattt atcaattcaa tcaatatcct atgcaggaat ttttcaatca
     4321 gttttctttt ctaaaagaag aaattgaacg atataaaaaa atggattaca ccattattct
     4381 gcagtctagc aattcaatgg gaagtaaaac attggaggat atgttagagg aatatcagat
     4441 taaattggat tctagagata agacaaatat ctgtaaagaa tctgtaaact taatagaggg
     4501 taatctcaga catggttttc attttgtaga tgaaaagatt ttattgataa ctgaacatga
     4561 gatttttcaa aagaaattaa agcgtcgttt tcgaagacaa catgtttcaa atgcagagag
     4621 attaaaagat tacaatgaac ttgaaaaagg ggactatgtt gtccatcata tccatgggat
     4681 tggtcaatat ctaggaattg aaaccattga aatcaaggga attcatcgcg attatgtcag
     4741 tgtccaatac caaaatggtg atcaaatttc tatccccgtg gaacagattc atctactgtc
     4801 caaatatatt tcaagtgatg gtaaagctcc aaaactcaat aaattaaatg acggtcattt
     4861 taaaaaggcc aagcaaaagg ttaagaacca ggtagaggat atagctgatg atttaatcaa
     4921 actctactct gaacgtagtc agttgaaggg ttttgctttc tcagctgatg atgatgatca
     4981 agatgccttt gatgatgctt tcccttatgt tgaaacggat gatcaacttc gtagtattga
     5041 ggaaatcaaa agggatatgc aggcttctca gccaatggat cgacttttag ttggggatgt
     5101 tggttttgga aagactgaag ttgctatgcg tgcagccttt aaagcagtca atgatcacaa
     5161 acaggttgtc attctagttc cgacgacggt tttagcgcaa cagcactata cgaattttaa
     5221 ggaacgattc caaaattttg cagttaatgt tgatgtgttg agtcgcttta gaagtaaaaa
     5281 agagcagact gcaacacttg aaaaattgaa aaacggtcaa gtcgatattt tgattggaac
     5341 acatcgtgtt ttgtcaaaag atgttgtgtt tgctgatttg ggcttgatga ttattgatga
     5401 ggaacagcga tttggtgtca agcataagga aactttgaaa gaactgaaga aacaagtgga
     5461 tgtcctaacc ttgaccgcta cgccaatccc tcgtaccctc catatgtcta tgctgggaat
     5521 cagagatttg tctgttattg aaactccgcc gactaatcgc tatcctgttc agacctatgt
     5581 tttggaaaag aatgatagtg tcattcgtga tgctgtcttg cgtgaaatgg agcgtggagg
     5641 tcaagtttac tatctttaca acaaagttga cacaattgtt cagaaggttt cagaattaca
     5701 ggagttgatt ccggaggctt cgattggata tgttcatggt cgaatgagtg aagtccagtt
     5761 ggaaaatact ctattagact ttattgaggg acaatacgat atcttggtga cgactactat
     5821 tattgagaca ggggtggaca ttccaaatgc taatacttta tttattgaaa atgcggacca
     5881 tatgggcttg tcaaccttat atcagttaag aggaagagtc ggtcgtagta atcgtattgc
     5941 ttatgcttat ctcatgtatc gtccagaaaa atcaatcagt gaagtctctg aaaagagatt
     6001 agaagcgatt aaaggattta cagaattggg ctctggcttt aagattgcaa tgcgagatct
     6061 ttcgattcgt ggagcaggaa atcttttagg aaaatcccag tctggtttca ttgattctgt
     6121 tggttttgaa ttgtattcgc agttattaga ggaagctatt gctaaacgaa acggtaatgc
     6181 taacgctaac acaagaacca aagggaatgc tgagttgatt ttgcaaattg atgcctatct
     6241 tcctgatact tatatttctg atcaacgaca taagattgaa atttacaaga aaattcgtca
     6301 aattgacaac cgtgtcaatt atgaagagtt acaagaggag ttgatagacc gttttggaga
     6361 atacccagat gtagtagcct atcttttaga gattggtttg gtcaaatcat acttggacaa
     6421 ggtctttgtt caacgtgtgg aaagaaaaga taataaaatt acaattcaat ttgaaaaagt
     6481 cactcaacga ctgtttttag ctcaagatta ttttaaagct ttatccgtaa cgaacttaaa
     6541 agcaggcatc gctgagaata agggattaat ggagcttgta tttgatgtcc aaaataagaa
     6601 agattatgaa attttagaag gtctgctgat ttttggagaa agtttattag agataaaaga
     6661 gtttaaggaa gaaaattcca tttgatattt ttcttctata aaatagataa aaatagataa
     6721 aaatggtaca ataataaatt gaggtaataa ggatgagatt agataaatat ttaaaagtat
     6781 cgcgaattat caagcgtcgt acagtcgcaa aggaagtagc agataaaggt agaatcaagg
     6841 ttaatggaat cttggccaaa agttcaacgg acttgaaagt taatgaccaa gttgaaattc
     6901 gctttggcaa taagttgctg cttgtaaaag tactagagat gaaagatagt acaaaaaaag
     6961 aagatgcagc aggaatgtat gaaattatca gtgaaacacg ggtagaagaa aatgtctaaa
     7021 aatattgtac aattgaataa ttcttttatt caaaatgaat accaacgtcg tcgctacctg
     7081 atgaaagaac gacaaaaacg gaatcgtttt atgggggggg tattgatttt gattatgcta
     7141 ttatttatct tgccaacttt taatttggcg cagagttatc agcaattact ccaaagacgt
     7201 cagcaattag cagacttgca aactcagtat caaactttga gtgatgaaaa ggataaggaa
     7261 acagcatttg ctaccaagtt gaaagatgaa gattatgctg ctaaatatac acgagcgaag
     7321 tactattatt ctaagtcgag ggaaaaagtt tatacgattc ctgacttgct tcaaaggtga
     7381 taaaatggaa aatttattag acgtaataga gcaatttttg agtttgtcag atgaaaagct
     7441 ggaagaattg actgataaaa atcaattatt gcgtttacaa gaagaaaagg aaaggaagaa
     7501 tgcgtaaatt cttaattatt ttgttgctac caagtttttt gaccatttca aaagtcgtta
     7561 gcacagaaaa agaagtcgtc tatacttcga aagaaattta ttacctttca caatctgact
     7621 ttggtattta ttttagagaa aaattaagtt ctcccatggt ttatggagag gttcctgttt
     7681 atgcgaatga agatttagta gtggaatctg ggaaattgac tcccaaaaca agttttcaaa
     7741 taaccgagtg gcgcttaaat aaacaaggaa ttccagtatt taagctatca aatcatcaat
     7801 ttatagctgc ggacaaacga tttttatatg atcaatcaga ggtaactcca acaataaaaa
     7861 aagcatggtt agaatctgac tttaaactgt acaatagtcc ttatgattta aaagaagtga
     7921 aatcatcctt atcagcttat tcgcaagtat caatcgacaa gaccatgttt gtagaaggaa
     7981 gagaatttct acatattgat caggctggat gggtagctaa agaatcaact tctgaagaag
     8041 ataatcggat gagtaaagtt caagaaatgt tatctgaaaa atatcagaaa gattctttct
     8101 ctatttatgt taagcaactg actactggaa aagaagctgg tatcaatcaa gatgaaaaga
     8161 tgtatgcagc cagcgttttg aaactctcct atctctatta tacgcaagaa aaaataaatg
     8221 agggtcttta tcagttagat acgactgtaa aatacgtatc tgcagtcaat gattttccag
     8281 gttcttataa accagaggga agtggtagtc ttcctaaaaa agaagataat aaagaatatt
     8341 ctttaaagga tttaattacg aaagtatcaa aagaatctga taatgtagct cataatctat
     8401 tgggatatta catttcaaac caatctgatg ccacattcaa atccaagatg tctgccatta
     8461 tgggagatga ttgggatcca aaagaaaaat tgatttcttc taagatggcc gggaagttta
     8521 tggaagctat ttataatcaa aatggatttg tgctagagtc tttgactaaa acagattttg
     8581 atagtcagcg aattgccaaa ggtgtttctg ttaaagtagc tcataaaatt ggagatgcgg
     8641 atgaatttaa gcatgatacg ggtgttgtct atgcagattc tccatttatt ctttctattt
     8701 tcactaagaa ttctgattat gatacgattt ctaagatagc caaggatgtt tatgaggttc
     8761 taaaatgagg gaaccagatt ttttaaatca ttttctcaag aagggatatt tcaaaaagca
     8821 tgctaaggcg gttctagctc tttctggtgg attagattct atgtttctat ttaaggtatt
     8881 gtctacttat caaaaagagt tagagattga attgattctg gctcatgtga atcataagca
     8941 gagaattgaa tcagattggg aagaaaagga attaaggaag ttggctgctg aagcagagct
     9001 tcctatttat atcagcaatt tttcaggaga attttcagaa gcgcgtgcac gaaattttcg
     9061 ttatgatttt tttcaagagg tcatgaaaaa gacaggtgcg acagctttag tcactgccca
     9121 ccatgctgat gatcaggtgg aaacgatttt gatgcgcttg attcgaggaa ctcgcttgcg
     9181 ctatctatca ggaattaagg agaagcaagt agtcggagag atagaaatca ttcgtccctt
     9241 cttgcatttt cagaaaaaag actttccatc aatttttcac tttgaagata catcaaatca
     9301 ggagaatcat tattttcgaa atcgtattcg aaattcttac ttaccaaaat tggaaaaaga
     9361 aaatcctcga tttagggatg caatcttagg cattggcaat gaaattttag attatgattt
     9421 ggcaatagct gaattatcta acaatattaa tgtggaagat ttacagcagt tattttctta
     9481 ctctgagtct acacaaagag ttttacttca aacttatctg aatcgttttc cagatttgaa
     9541 tcttacaaaa actcagtttg ctgaagttca gcagatttta aaatctaaaa gccagtatcg
     9601 tcatccgatt aaaaatggct atgaattgat aaaagagtac caacagtttc agatttgtaa
     9661 aatcagtccg caggctgatg aaaaggaaga tgaacttgtg ttacactatc aaaatcaggt
     9721 agcttatcaa ggatatttat tttcctttgg acttccatta gaaggtgaat taattcaaca
     9781 aatacctgtt tcacgtgaaa catccataca cattcgtcat cgaaaaacag gagatgtttt
     9841 gattcaaaat gggcatagaa aaaaactcag acgtttattt attgatttga aaatccctat
     9901 ggaaaagaga aactctgctc ttattattga gcaatttggt gaaattgtct caattttggg
     9961 aattgcgacc aataatttga gtaaaaaaac gaaaaatgat ataatgaaca ctgtacttta
    10021 tatagaaaaa atagataggt aaaaaatgtt agaaaacgat attaaaaaag tcctcgtttc
    10081 acacgatgaa attacagaag cagctaaaaa actaggtgct caattaacta aagactatgc
    10141 aggaaaaaat ccaatcttag ttgggatttt aaaaggatct attcctttta tggctgaatt
    10201 ggtcaaacat attgatacac atattgaaat ggacttcatg atggtttcta gctaccatgg
    10261 tggaacagca agtagtggtg ttatcaatat taaacaagat gtgactcaag atatcaaagg
    10321 aagacatgtt ctatttgtag aagatatcat tgatacaggt caaactttga agaatttgcg
    10381 agatatgttt aaagaaagag aagcagcttc tgttaaaatt gcaaccttgt tggataaacc
    10441 agaaggacgt gttgtagaaa ttgaggtaga ctatacctgc tttactatcc caaatgagtt
    10501 tgtagtaggt tatggtttag actacaaaga aaattatcgt aatcttcctt atattggagt
    10561 attgaaagag gaagtgtatt caaattagaa agaataatct ttaatgaaaa aacaaaataa
    10621 tggtttaatt aaaaatcctt ttctatggtt attatttatc tttttccttg tgacaggatt
    10681 ccagtatttc tattctggga ataactcagg aggaagtcag caaatcaact atactgagtt
    10741 ggtacaagaa attaccgatg gtaatgtaaa agaattaact taccaaccaa atggtagtgt
    10801 tatcgaagtt tctggtgtct ataaaaatcc taaaacaagt aaagaaggaa caggtattca
    10861 gtttttcacg ccatctgtta ctaaggtaga gaaatttacc agcactattc ttcctgcaga
    10921 tactaccgta tcagaattgc aaaaacttgc tactgaccat aaagcagaag taactgttaa
    10981 gcatgaaagt tcaagtggta tatggattaa tctactcgta tccattgtgc catttggaat
    11041 tctattcttc ttcctattct ctatgatggg aaatatggga ggaggcaatg gccgtaatcc
    11101 aatgagtttt ggacgtagta aggctaaagc agcaaataaa gaagatatta aagtaagatt
    11161 ttcagatgtt gctggagctg aggaagaaaa acaagaacta gttgaagttg ttgagttctt
    11221 aaaagatcca aaacgattca caaaacttgg agcccgtatt ccagcaggtg ttcttttgga
    11281 gggacctccg gggacaggta agactttgct tgctaaggca gtcgctggag aagcaggtgt
    11341 tccattcttt agtatctcag gttctgactt tgtagaaatg tttgtcggag ttggagctag
    11401 tcgtgttcgc tctctttttg aggatgccaa aaaagcagca ccagctatca tctttatcga
    11461 tgaaattgat gctgttggac gtcaacgtgg agttggtctc ggcggaggta atgacgaacg
    11521 tgaacaaacc ttgaaccaac ttttgattga gatggatggt tttgagggaa atgaagggat
    11581 tatcgtcatc gctgcgacaa accgttcaga tgtacttgat cctgcccttt tgcgtccagg
    11641 acgttttgat agaaaagtat tggttggccg tcctgatgtt aaaggtcgtg aagcaatctt
    11701 gaaagttcac gctaagaaca agcctttagc agaagatgtt gatttgaaat tagtggctca
    11761 acaaactcca ggctttgttg gtgctgattt agagaatgtc ttgaatgaag cagctttagt
    11821 tgctgctcgt cgcaataaat cgataattga tgcttcagat attgatgaag cagaagatag
    11881 agttattgct ggaccttcta agaaagataa gacagtttca caaaaagaac gagaattggt
    11941 tgcttaccat gaggcaggac ataccattgt tggtctagtc ttgtcgaatg ctcgcgttgt
    12001 ccataaggtt acaattgtac cacgcggccg tgcaggcgga tacatgattg cacttcctaa
    12061 agaggatcaa atgcttctat ctaaagaaga tatgaaagag caattggctg gcttaatggg
    12121 tggacgtgta gctgaagaaa ttatctttaa tgtccaaact acaggagctt caaacgactt
    12181 tgaacaagcg acacaaatgg cacgtgcaat ggttacagag tacggtatga gtgaaaaact
    12241 tggcccagta caatatgaag gaaaccatgc tatgtttggt gcacagaatc ctcaaaaatc
    12301 aatttcagaa caaacagctt atgaaattga tgaagaggtt cgttcattat taaataaggc
    12361 acgaaataaa gctgctgaaa ttattcagtc aaatcgtgaa actcacaagt taattgcaga
    12421 agcattattg aaatacgaaa cattggatag tacacaaatt aaagctcttt acgaaacagg
    12481 aaagatgcct gaagcagtag aagaggaatc tcatgcacta tcctatgatg aagtaaagtc
    12541 aaaaatgaat gacgaaaaat aaccctgaga gaggctggag cctctctttt ttgtgcagtt
    12601 taggagctaa agggaacaga atggagaaaa tggaacaaat gtgttttcta atctgttaga
    12661 ctgtatctag aaaggggaaa attatgatta aagaattgta tgaagaagtc caagggactg
    12721 tgtataagtg tagaaatgaa tattaccttc atttatggga attatcggat tgggaccaag
    12781 aaggcatgct ctgcttacat gaattgatta gtagagaaga aggactggta gacgatattc
    12841 cacgtttaag gaaatatttc aaaaccaagt ttcgaaatcg aattttagac tatatccgta
    12901 agcaggaaag tcagaagcgt agatacgata aagaacccta tgaagaagtg ggtgagatca
    12961 gtcatcgtat aagtgagggg ggtctctggc tagatgatta ttatctcttt catgaaacac
    13021 taagagatta tagaaacaaa caaagtaaag agaaacaaga agaactagaa cgcgtcttaa
    13081 gcaatgaacg atttcgaggg cgtcaaagag tattaagaga cttacgcatt gtgtttaagg
    13141 agtttactat ccgtacccat tagtaagtca tgcaaaaaaa atgaaaaaaa ttagaaaaag
    13201 tagttgacaa agtttgaaaa ggctgtataa tagtaagagt tgaaaataac aactcaggtc
    13261 cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt cgaatcccgt
    13321 acggactatg gtatgttgcg gttggaacac ttgatgaaaa aaagtttaaa aaaacttaaa
    13381 aatcttcaaa aaagtgttga caagtgaaag tggctgtgat atactaatat agttgtcgct
    13441 tgagagaagc aagtgacaaa gacctttgaa aactgaacaa gacgaaccaa tgtgcagggc
    13501 gctacaacat aagttgtagt actgaacaat gaaaaaaaca ataaatctgt cagtgacaga
    13561 aatgagtaag aactcaaact tttaatgaga gtttgatcct ggctcaggac gaacgctggc
    13621 ggcgtgccta atacatgcaa gtagaacgct gaaggaggag cttgcttctc tggatgagtt
    13681 gcgaacgggt gagtaacgcg taggtaacct gcctggtagc gggggataac tattggaaac
    13741 gatagctaat accgcataag agtggatgtt gcatgacatt tgcttaaaag gtgcacttgc
    13801 atcactacca gatggacctg cgttgtatta gctagttggt ggggtaacgg ctcaccaagg
    13861 cgacgataca tagccgacct gagagggtga tcggccacac tgggactgag acacggccca
    13921 gactcctacg ggaggcagca gtagggaatc ttcggcaatg gacggaagtc tgaccgagca
    13981 acgccgcgtg agtgaagaag gttttcggat cgtaaagctc tgttgtaaga gaagaacgag
    14041 tgtgagagtg gaaagttcac actgtgacgg tatcttacca gaaagggacg gctaactacg
    14101 tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc cggatttatt gggcgtaaag
    14161 cgagcgcagg cggttagata agtctgaagt taaaggctgt ggcttaacca tagtaggctt
    14221 tggaaactgt ttaacttgag tgcaagaggg gagagtggaa ttccatgtgt agcggtgaaa
    14281 tgcgtagata tatggaggaa caccggtggc gaaagcggct ctctggcttg taactgacgc
    14341 tgaggctcga aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgctgtaaa
    14401 cgatgagtgc taggtgttag accctttccg gggtttagtg ccgtagctaa cgcattaagc
    14461 actccgcctg gggagtacga ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca
    14521 caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac
    14581 atccctctga ccgctctaga gatagagttt tccttcggga cagaggtgac aggtggtgca
    14641 tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt cccgcaacga gcgcaacccc
    14701 tattgttagt tgccatcatt cagttgggca ctctagcgag actgccggta ataaaccgga
    14761 ggaaggtggg gatgacgtca aatcatcatg ccccttatga cctgggctac acacgtgcta
    14821 caatggctgg tacaacgagt cgcaagccgg tgacggcaag ctaatctctt aaagccagtc
    14881 tcagttcgga ttgtaggctg caactcgcct acatgaagtc ggaatcgcta gtaatcgcgg
    14941 atcagcacgc cgcggtgaat acgttcccgg gccttgtaca caccgcccgt cacaccacga
    15001 gagtttgtaa cacccgaagt cggtgaggta accgtaagga gccagccgcc taaggtggga
    15061 tagatgattg gggtgaagtc gtaacaaggt agccgtatcg gaaggtgcgg ctggatcacc
    15121 tcctttctaa ggataaggaa ctgcgcattg gtcttgttta gtcttgagag gtcttgtggg
    15181 gccttagctc agctgggaga gcgcctgctt tgcacgcagg aggtcagcgg ttcgatcccg
    15241 ctaggctcca ttggtgagag atcaccaagt aatgcacatt gaaaattgaa tatctatatc
    15301 aaatagtaac aagaaaataa accgaaaacg ctgtagtatt aataagagtt tatgactgaa
    15361 aggtcagaaa ataaggttaa gttaataagg gcgcacggtg gatgccttgg cactaggagc
    15421 cgacgaagga cgtgacaaac gacgatatgc cttgggtagc tgtaagtaag cgatgatcca
    15481 gggatttccg aatgggggaa cccaacaggt aatacctgtt acccacatct gttaaggatg
    15541 tgaggaggaa gacgcagtga actgaaacat ctaagtagct gcaggaagag aaagcaaaag
    15601 cgattgcctt agtagcggcg agcgaaacgg cagaagggca aaccgaagag tttactcttc
    15661 ggggttgtag gactgcaatg tggactcaaa gattatagaa gaatgatttg ggaagatcag
    15721 ccaaagagag taatagcctc gtatttaaaa tagtctttgt acctagcagt atcctgagta
    15781 cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc atctcccaac cctaaatact
    15841 ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg tgaaaagcac cccgggaggg
    15901 gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt cgagcccgtt aatgggtgag
    15961 agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg atgcgaggtt aagttgaaga
    16021 gacggagccg tagggaaacc gagtctgaat agggcgcctt agtatcatga cgtagacccg
    16081 aaaccatgtg acctacccat gagcaggttg aaggtgcggt aagacgcact ggaggaccga
    16141 accagggcac gttgaaaagt gcttggatga cttgtgggta gcggagaaat tccaaacgaa
    16201 cttggagata gctggttctc tccgaaatag ctttagggct agcgtcgaca ttagagattc
    16261 ttggaggtag agcactgttt gggtgagggg tccatcccgg attaccaatc tcagataaac
    16321 tccgaatgcc aatgaattat ggtcggcagt cagactgcga gtgctaagat ccgtagtcga
    16381 aagggaaaca gcccagacca ccagctaagg tcccaaaata attgttaagt ggaaaaggat
    16441 gtggggttgc acagacaact aggatgttag cttagaagca gctattcatt caaagagtgc
    16501 gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt accggggcta aaacaattta
    16561 ccgaagctgt ggataccttt ataggtatgg taggagagcg ttctatgtgt gatgaaggta
    16621 taccgtgagg agtgctggaa cgcatagaag tgagaatgcc ggtatgagta gcgaaagaca
    16681 ggtgagaatc ctgtccaccg taagactaag gtttccaggg gaaggctcgt ccgccctggg
    16741 ttagtcggga cctaaggaga gaccgaaagg tgtatccgat ggacaacagg ttgatattcc
    16801 tgtactagag tatgtagtga tggagggacg cagtaggcta actaaagcag acgattggaa
    16861 gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc ttaattctat aacattgagc
    16921 tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt cacactgcca agaaaagctt
    16981 ctagcgttta aacatactct acccgtaccg caaaccgaca caggtagtcg aggcgagtag
    17041 cctcaggtga gcgagagaac tctcgttaag gaactcggca aaatgacccc gtaacttcgg
    17101 gagaaggggt gctgacttta agtcagccgc agtgaatagg cccaagcaac tgtttatcaa
    17161 aaacacagct ctctgctaaa tcgtaagatg atgtataggg ggtgacgcct gcccggtgct
    17221 ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga attgaagccc cagtaaacgg
    17281 cggccgtaac tataacggtc ctaaggtagc gaaattcctt gtcgggtaag ttccgacccg
    17341 cacgaaaggc gtaatgattt gggcactgtc tcaacgagag actcggtgaa attttagtac
    17401 ctgtgaagat gcaggttacc cgcgacagga cggaaagacc ccatggagct ttactgcagt
    17461 ttgatattga gtgtctgtac cacatgtaca ggataggtag gagtctaaga gatcgggacg
    17521 ccagtttcga aggagacgct gttgggatac tacccttgtg ttatggccac tctaacccag
    17581 ataggtgatc cctatcggag acagtgtctg acgggcagtt tgactggggc ggtcgcctcc
    17641 taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg ttggaaatca ttcgcagagt
    17701 gtaaaggtat aagggagctt gactgcgaga gctacaactc gagcagggac gaaagtcggg
    17761 cttagtgatc cggtggttcc gtatggaagg gccatcgctc aacggataaa agctaccctg
    17821 gggataacag gcttatctcc cccaagagtt cacatcgacg gggaggtttg gcacctcgat
    17881 gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg gttgggctgt tcgcccatta
    17941 aagcggcacg cgagctgggt tcagaacgtc gtgagacagt tcggtcccta tccgtcgcgg
    18001 gcgtaggaaa tttgagagga tctgctccta gtacgagagg accagagtgg acttaccgct
    18061 ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct atgtagggaa gggataaacg
    18121 ctgaaagcat ctaagtgtga aacccacctc aagatgagat ttcccatgat tatatatcag
    18181 taagagccct gagagatgat caggtagata ggttagaagt ggaagtgtgg cgacacatgt
    18241 agcggactaa tactaatagc tcgaggactt atccaaagta actgagaata tgaaagcgaa
    18301 cggttttctt aaattgaata gatattcaat tttgagtagg tattactcag agttaagtga
    18361 cgatagccta ggagatacac ctgtacccat gccgaacaca gaagttaagc cctagaacgc
    18421 cggaagtagt tgggggttgc cccctgtg
//
LOCUS       DAVIME010000042        18365 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVIME010000042 DAVIME010000000
VERSION     DAVIME010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.042"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(45..854)
                     /locus_tag="VV588_001581"
     CDS             complement(45..854)
                     /locus_tag="VV588_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU7083892.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(856..1659)
                     /locus_tag="VV588_001582"
     CDS             complement(856..1659)
                     /locus_tag="VV588_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU7083893.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1669..3156)
                     /gene="tacF"
                     /locus_tag="VV588_001583"
     CDS             complement(1669..3156)
                     /gene="tacF"
                     /locus_tag="VV588_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU7083894.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3492..4199
                     /locus_tag="VV588_001584"
     CDS             3492..4199
                     /locus_tag="VV588_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU7083895.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLHKERIIITKGGADRNTSIEKIIEAIDAYRPL
                     TSEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4204..5226
                     /locus_tag="VV588_001585"
     CDS             4204..5226
                     /locus_tag="VV588_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU7083896.1"
                     /translation="MINQIYQLTKPKFINVKYQEEVIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5243..6112
                     /gene="licA"
                     /locus_tag="VV588_001586"
     CDS             5243..6112
                     /gene="licA"
                     /locus_tag="VV588_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU7083897.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIEFAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6102..6980
                     /locus_tag="VV588_001587"
     CDS             6102..6980
                     /locus_tag="VV588_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU7083898.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            6992..7681
                     /locus_tag="VV588_001588"
     CDS             6992..7681
                     /locus_tag="VV588_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU7083899.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEIFKNEN"
     gene            7777..8625
                     /gene="dprA"
                     /locus_tag="VV588_001589"
     CDS             7777..8625
                     /gene="dprA"
                     /locus_tag="VV588_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU7083900.1"
                     /translation="MKITNYEIYKLKKSSLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9509..10552
                     /locus_tag="VV588_001590"
     CDS             9509..10552
                     /locus_tag="VV588_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU7083901.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10719..12806
                     /gene="topA"
                     /locus_tag="VV588_001591"
     CDS             10719..12806
                     /gene="topA"
                     /locus_tag="VV588_001591"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU7083902.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            12912..13271
                     /locus_tag="VV588_001592"
     CDS             12912..13271
                     /locus_tag="VV588_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU7083903.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13364..13996
                     /locus_tag="VV588_001593"
     CDS             13364..13996
                     /locus_tag="VV588_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU7083904.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14040..14696
                     /locus_tag="VV588_001594"
     CDS             14040..14696
                     /locus_tag="VV588_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU7083905.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14715..15809
                     /locus_tag="VV588_001595"
     CDS             14715..15809
                     /locus_tag="VV588_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU7083906.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGIAVANSLAAVKNGAGRVEETINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLTETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQERVLVTVENRDTETILNAAGLDFDVLKASA
                     IAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15821..16858
                     /gene="leuB"
                     /locus_tag="VV588_001596"
     CDS             15821..16858
                     /gene="leuB"
                     /locus_tag="VV588_001596"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU7083907.1"
                     /translation="MAKKIVALAGDGIGPEIMEAGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGSPLPDETLKASREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILLVVMMLRDSFGRYEDTERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            16855..17124
                     /locus_tag="VV588_001597"
     CDS             16855..17124
                     /locus_tag="VV588_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU7083908.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17128..17487
                     /gene="leuD"
                     /locus_tag="VV588_001598"
     CDS             17128..17487
                     /gene="leuD"
                     /locus_tag="VV588_001598"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU7083909.1"
                     /translation="MVGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17649..18272
                     /locus_tag="VV588_001599"
                     /pseudo
     CDS             17649..18272
                     /locus_tag="VV588_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         5749 a         3159 c         3890 g         5567 t
ORIGIN      
        1 ttttgaataa cctctatctt agtagtttgt ataatacccc tcaatcagtt tttgcgataa
       61 gctttaatgc tatgactata ccactcttgc atttcttttg atggtggtgt catataatcg
      121 ccatacatct gggttaaaaa ttggtcatat tttttgggaa caggcaacat acggccctca
      181 aactcagtta aaatcagttc tttaaaggta tcaactggga agatttcttt catcccttcc
      241 ttaccgatcc caactcctcc ttcatattga ggagtgttgg ttacagcatt tttgactagt
      301 tgatcaattt tcttgtaaaa gtagcgagga ttgacaaatc ggagagcgta ccagctacat
      361 aatctaagaa aatcttttag tttgctatca ccgtgaactg ctcgtgattt tttgatataa
      421 gctagttgac gaagagccac atacttatag ctcttgtcga caatgctcaa gtctgtaaat
      481 cgatcaattg ggaagacatc gatgaaaagg ctggtatcat gacgcttgta cttaacatgg
      541 tcttctataa cagtagaagt gtccaaaatc gatgcgaaat tatggaagta ccaagaagat
      601 gtatcgtagg aaagaacctt gtagcgaggg tgattttctt cttcaataat cttcagtaaa
      661 cgctcataat cctcacgata aagggaaata tcaatatcat catcccaagg aatcatacct
      721 ttgtggcgga tggctccaag catggttcca taactgagaa aataaggaat atcatgtttc
      781 ttacaagtct catcaatata gtccagcagg gctagttgaa tttctttaat ttcttttttt
      841 tctaaatatt gcatcctaat cctccaattt ataagcgtga aattcatgac tgtagaagcg
      901 tttttcttct ggtggtaggg tcatataatc tccataaaat tgtgtcaaaa tagtatcaaa
      961 tttttcaggt gcaggaaggc ttaaattctc aaagggtaaa tcgattgttt tatcaaaggt
     1021 accacttggg aagacttcct tttccttaaa ttttgaagga ataaaagcca tatactgccc
     1081 attttcacga ctatattttt gaatttcttt ctcgatttta tttgcaaaat aacgaggaga
     1141 aaccggtcga aggagcaacc aaaaggctgt tcgtatccaa tcttttaaaa ggctatcctt
     1201 atagacaata tttttatgtt tactgaaaga cagcagtttg aagctttcca gtttataaca
     1261 agtatcaatg accttaggat catcaaagcg atctataggg aaaatatcga taaagatacc
     1321 agactcatag gtttttgtat ttcgagtatc aataatttta gttgtactgt cggttatctt
     1381 gataaagttg ttaaagtagt tcttatcagt ttctaaggat aggagcttat acttgctttt
     1441 ttccttttga aaaatgttaa taaatcgttg gtagtcttct ctaggcatgg ataaatcaat
     1501 atcgtcgtcc caagggataa agccctcatg tcgaaccgcc ccaatcagag taccgtagtt
     1561 aataatatag ttgatattgt gctttttaca gagagtatca atataattca aaatttctaa
     1621 ttcaatttgt ttggcatctt caacggttag ttgtttcatt ttaaactcct aagatttttt
     1681 aaatttattt tttaaggcta ggacatggtt taaaaattca tagaaaatgc tatcttttgt
     1741 gaagacaagt agactaatat aagagatagc tgatagcaag acaatcaaac cagtattaat
     1801 caaaaatggc aaattaatga ccatatccac aggatacatg aaattaatca ggaaataaat
     1861 tgctacaaag gaaagtgaaa agagagagta tcgaacagta tagctaaaga tatgtcccaa
     1921 gtggatgagt tgttttctat ggatgaaaat gatatagaaa acaagtagag aagtctctga
     1981 taacatagtt gtcagtaagt agtattcagg agccacgata tggttgaaaa agaggagact
     2041 attcaagccc aaattgagta gcccagcaaa gactgtatag actgtgatac gtttttcata
     2101 gccattggta aagagaattt gggaaccaag aatggtatct aaggccagga taatcgtacg
     2161 aaaagcgaag agagaggtca agatgccgcc tccgatatat ttttcactac cgtaaagtag
     2221 gatggcattt ggtcctaaaa ccatgagtcc aaaactcagt ggaatgataa agaagttaaa
     2281 gattcgacta cctctattaa ccagagaaac ataggcttct ttgtctcctt tccccagata
     2341 gtaactgaga cgaggcacac tcactccaat tgcacctgtt acaaccccag ctataacggt
     2401 cacaattcgc tgagctatgg tatagtaact aacgttgaca tcaatccctg ttttaacgag
     2461 gaagaggcga tctaaaaaag tgaagagcat attggcattg gcaaagacta acatggctgt
     2521 cagagggaga aagagtggtt taaaatcact taggtgaatt ttaacaagtt tgatgtctct
     2581 tttaatccaa aaataactaa tcaggtagtt aatcagcgtc gataaactca tcacaagtgt
     2641 atagacaaca atatcgtgtt catttttaac aaataagaaa atagagacca gcatcaggat
     2701 acggatgaag gcagttttgt aaaagagaaa actgtaattt tccagagctt cattgaccca
     2761 ttcgattgaa aaaatctggg caatgagttg aatccccata acaaggtaga cctttttgac
     2821 gattggatta tcagtaaaga agagaggata ggctaggata tagacagcag tggtcaaaat
     2881 cgtacaagcg atgcacaaat aaaaaagact agaaaaggtt ctgttaagat cttttttgtt
     2941 atccttgaca ttactgatag cccttaaacc gtagttatag acaccataag ttgcaaaggg
     3001 caagaaaaat gacaaaatag tgtcgactga gttgaagtaa ccatagtcag ttcggtccaa
     3061 gacacgcgcg acataggttc cagttaggat gggaaaaata atattcaaga cacgaattcc
     3121 catgtaagat agagcattta attttatact tttcattcaa tttacctcgt ttttcattat
     3181 atcataaagt tagctaataa gaaatgaagg gcagtaagtc aagtaatcac tttgaagttt
     3241 caaatcttaa attttaagtt ttctttaagg aaagtatatt attctgaagg actctaaaat
     3301 ttcgcagcca tttattagta attgctacag aattcctagt cattactaga aatgaactag
     3361 tttctttgaa taatagaact gcataattct cctattctag aaggggagga ccagtatttc
     3421 ttttatgata ggactagatt gtggtataat agagagaata agttttttta gtaagacaaa
     3481 ggagaaaata gatgatttat gcaggaattc ttgccggtgg aactggcaca cgcatgggaa
     3541 tcagtaactt gccaaaacaa tttttagagc taggtgatcg acctattttg attcatacaa
     3601 ttgaaaaatt tgtcttggag ccaagtattg aaaaaattgt agttggggtt catggagact
     3661 gggtttctca tgcagaagat cttgtagata aatatcttcc tcttcacaag gaacgtatca
     3721 tcattacaaa gggtggtgct gaccgcaata caagtattga gaaaatcatt gaagccattg
     3781 atgcttatcg tccgcttact tcagaggata tcgttgttac ccacgattct gttcgtccat
     3841 ttattacact tcgcatgatt caggacaata tccaacttgc ccaaaatcat gacgcagtgg
     3901 acacagtggt agaagcggtt gatactatcg ttgaaagtac caatggtcaa tttattacag
     3961 atattccaaa tcgtgctcac ctttatcaag gacaaacacc tcaaacattc cgttgcaagg
     4021 acttcatgga cctttatgga tctctttctg atgaagagaa ggaaatcttg acagatgcat
     4081 gtaaaatctt tgtgatcaaa ggaaaagatg tggccttggc caaaggtgaa tactcaaatc
     4141 tgaagattac aaccgtaaca gatttgaaga ttgcaaaaag tatgattgag aaagactagt
     4201 aaaatgatta atcaaattta tcaactaact aagcctaagt ttatcaatgt caaatatcag
     4261 gaagaggtta ttgaccaaga gaatcatatc cttatccgtc ccaactacat ggctgtctgt
     4321 catgcggatc agcgttacta tcagggaaaa cgtgatccca agattttgaa taaaaagctt
     4381 ccaatggcaa tgattcacga gtcatgtgga accgtcattt ctgacccgac cggaacctac
     4441 gaggttggtc aaaaagttgt catgattccc aatcagtctc ctatgcagag tgatgaagaa
     4501 ttctatgaaa actacatgac agggacccat ttcttgtcta gtggatttga tggctttatg
     4561 agagagtttg tttctctccc taaagatcgt gtggtggctt atgatgctat tgaagatacg
     4621 gttgcagcca ttacagagtt tgtcagtgtg ggcatgcacg ctatgaatcg tctattgact
     4681 cttgctcata gcaagcggga gcggatcgcc gttattggag atggaagttt agcttttgtg
     4741 gttgccaata ttatcaacta tactttgcca gaagcagaga ttgtggttat tggtcgtcat
     4801 tgggaaaagt tggaactctt ctcatttgcc aaagaatgct atattacgga taatattcct
     4861 gaagatttgg cctttgacca tgcttttgaa tgttgtggtg gtgatggtac tggaccagct
     4921 attaatgact tgattcgcta cattcgtcct cagggaacga ttctcatgat gggagttagc
     4981 gaatataaag tcaatctcaa tactcgcgat gccttagaaa agggcttgat tttggttggg
     5041 tcatctcgtt ctggtcgcat tgattttgaa aatgctatcc aaatgatgga agtcaagaaa
     5101 tttgccaatc gtcttaaaaa tatcctttat ctagaagaac ctgtaagaga aattaaagat
     5161 attcatcgtg tctttgcaac cgatttaaac acagccttta aaacagtgtt taagtgggaa
     5221 gtataagtac tggaggttaa ttgtggagaa aatcattaaa gaaaaaattt cttccttact
     5281 tagtcaagaa gaggaagtcc tcagtgttga acaactgggt ggaatgacca atcaaaacta
     5341 tttggccaaa acaacaaata agcaatacat tgttaaattc tttggtaaag ggacagaaaa
     5401 gcttatcaat cgacaagatg aaaagtacaa tcttgaacta ctaaaggatt taggcttaga
     5461 tgtaaaaaat tatctttttg atattgaagc tggtatcaaa gtaaatgagt atatcgaatt
     5521 tgcgattacg cttgattcaa cgtcaatcaa gaccaagttc gacaaaattg ctccaatatt
     5581 acaaactatt catacgtctg ctaaggaatt aagaggagaa tttgctcctt ttgaagaaat
     5641 caaaaaatac gaatccttga ttgaagaaca aattccttat gccaactatg aatctgttag
     5701 aaatgcagtc ttctccttag agaaaagact ggctgactta ggtgttgaca gaaaatcttg
     5761 tcatatcgat ttggtgcctg aaaactttat cgaatcacct caaggacgac tttatttgat
     5821 tgactgggaa tattcatcaa tgaatgatcc aatgtgggat ttggctgccc tctttttaga
     5881 gtctgaattc acttcccaag aggaagaaac tttcttatct cactatgaga gtgaccaaac
     5941 accggtttct catgaaaaga ttgctattta taaaatttta caagatacta tttggagtct
     6001 atggactgtc tataaggaag agcaaggtga agattttggt gactatggtg tgaatcgtta
     6061 ccaaagagct gttaaaggtt tggcttctta tggaggttca gatgaaaagt aaaaacggag
     6121 ttccttttgg ccttctctca ggtattttct ggggcttggg tctaacggtt agtgcttata
     6181 tcttttcgat ttttacagat ttgtcaccct ttgtggtggc tgcagctcat gattttttga
     6241 gcatctttat cttactagct tttctcttgg taaaagaagg gaaagttcgc ctctcaattt
     6301 tcttaaatat tcgcaatgtc agtgttatca tcggagcctt gctagcaggc cctatcggta
     6361 tgcaggccaa tctttatgca gttaagtata tcggaagttc tttagcttca tctgtatcgg
     6421 ctatttaccc tgcgatttca gttctattgg ctttcttctt tttgaagcac aagatttcga
     6481 aaaatactgt atttgggatt gtcttgatta ttggagggat tattgctcag acctataagg
     6541 ttgaacaggt taattctttc tacattggga ttctttgtgc tttggtttgt gctattgcat
     6601 ggggaagtga gagtgttctt agctcttttg ccatggaaag tgaattgagt gaaatcgaag
     6661 ccctcttaat ccgtcaagta acttcgttct tgtcctatct tgtgattgtg ctcttctctc
     6721 atcagtcatt tactgcagta gccaatggac aattgctagg tctcatgatt gtttttgcag
     6781 cctttgatat gatttcctac ttggcttatt atatcgctat caatcgcttg caaccagcca
     6841 aggctacagg cttgaacgtg agctatgtag tatggacggt cttgtttgca gttgttttct
     6901 tgggtgcacc gctagatatg ctgaccatta tgacgtcact tgtcgtcatt gctggagttt
     6961 atattattat taaagaataa aggagattcg tgtgaaagcc attatcttag cagcgggatt
     7021 gggaactcgc ttgcgtccta tgactgaaaa tacccctaaa gccttggttc aggttaatca
     7081 aaaaccctta attgagtacc aaattgagtt tctcaaagaa aaaggaatca atgacatcat
     7141 catcattgtt ggttatctta aagaacaatt cgattactta aaagaaaaat acggtgttcg
     7201 cctcgttttc aatgataaat acgctgacta caataacttt tactctctct atcttgtaaa
     7261 agaagaattg gccaacagct atgttattga tgctgacaat tatctcttta aaaatatgtt
     7321 ccgcaatgat ttgactcgtt cgacttattt tagtgtttat cgtgaagatt gtaccaacga
     7381 atggttcttg gtctatggag atgactacaa ggttcaagac attattgttg atagcaaggc
     7441 aggtcgcatc cttagtggtg tatccttctg ggatgctcca actgcagaaa agattgtcag
     7501 ctttatcgat aaggcttatg caagtggcga atttgttgat ctctattggg acaatatggt
     7561 taaggataat atcaaagagc tagatgtcta tgttgaagaa ttagaaggca atagcattta
     7621 tgagatcgat agtgtccaag actatcgtaa attagaagaa atttttaaaa acgaaaatta
     7681 aagattccaa catctgacaa aatagtcgga tgttttttga ttttttacga acttttacga
     7741 atagatagat gagtagaaaa agaaatggag ttatttatga aaatcacaaa ctatgaaatc
     7801 tataagttaa aaaaatcaag tttgaccaat caacagattt tgaaagttct agaatacggt
     7861 gaaaatgttg atcaggagct tttgttgggt gatattgcag atatatcagg ttgccgtaat
     7921 ccagccgttt ttatggaacg ttattttcag atagacgatg cgcatttgtc gaaagagttt
     7981 caaaaatttc catctttctc tattttagat gactgttatc cttgggattt gagtgaaata
     8041 tatgatgcgc ctgtactttt attttacaag ggaaatcttg acctcctgaa attcccgaag
     8101 gtagcggtcg tgggcagtcg tgcttgtagc aaacagggag ctaagtcagt tgaaaaagtc
     8161 attcaaggct tggaaaatga actggttatt gtcagtggtc tggccaaggg cattgacaca
     8221 gcagctcata tggcagctct tcagaatggc ggaaaaacca ttgcagtgat tggaacagga
     8281 ctggatgtgt tttatcctaa agccaataaa cgcttgcaag actacatcgg caatgaccat
     8341 ctggttctaa gtgaatatgg acctggcgaa caacctctga aatttcattt tcctgcccgt
     8401 aatcgcatca ttgctggact ttgtcgtggt gtgattgtag cagaggctaa gatgcgttca
     8461 ggtagtctca ttacgtgtga gcgagcaatg gaagaaggac gcgatgtctt tgctattcct
     8521 gatagcattt tagatggact atcagacggt tgccatcatt tgattcaaga aggagcaaaa
     8581 ttggtcacca gtgggcaaga tgttcttgcg gaatttgaat tttaaaaatg acctaagcta
     8641 gaattctaag aaaaaatcaa ttttaagaga aaatgaaccc aacatttcca taataaaacg
     8701 catattagca agtttttaac acttgataat atgcgttttt tctaagtgga ttagtagagt
     8761 agaggatttt tctcatataa tactcttcga aaatctcttc aaactacgtc agcttccatc
     8821 tgcaacctca aaacagtatt ttgagctgac ttcgtcagtc ttatctacaa cctcaaagca
     8881 gtgctttgag caacctgtgg ctagcttcct agtttgcgct ttgattttca ttgagtataa
     8941 gggaaagtat agtgaattga aataagatgt gaacaactct atcaggaaag tcaaattaat
     9001 ttatagaaat attttagcag ccaaggtgca ctgttataga ttcaatacac tataatttag
     9061 tgtaattgag aaaggagaaa tgattgtgat tgatgttggc taggttatgt tcaatgattc
     9121 ctaccgtctc aaatcttgtc agtaaggaaa aataaattct tcaaaagtag agattacaag
     9181 gcttgtttaa gaaagaattc aaagaccttg acaaataaaa ataaaatggt tattataaga
     9241 aatggtctaa aatagatgat gatacttttc gaaaatcttt ttacgtcagc tcagctttgc
     9301 cttgctgtgt tttgagcaag ctacggttag cttccgagtt tgattttcat ttactagaaa
     9361 tgaaactgat gagagatatc agtagacatt tgagtcagga tattatggaa aatgataaaa
     9421 agagctcgtg agattggcat atcagactac taaagtattg agtttgttag gattttagcg
     9481 actagttagc tgggaaagga agatatttgt gacaaataat aaactgtatt cgttgataga
     9541 atttagaaat aaaatatatg aagaattaga actttccaga agtgatttag cgattttact
     9601 atgtgccatg cttatcgcct ctatcggatt aaatatggat tcgactcccg tgattattgg
     9661 agccatgtta atctctcctt tgatgacacc tattctggga gtggggctct ctctagctat
     9721 atttgatttt aaattgttaa gaaaatcttt taaaatatta gctattcaaa ttcttgccag
     9781 tctaatagct tcaacacttt atttttatct ttctcccatt tcgtatgcta gttcggagat
     9841 tgttgctaga acctctccga ctatttggga tgttctcatt gcttttgtag gagggatagc
     9901 aggtattatt ggtgctagga aaaaagagac caataatatt gttcctggtg ttgctattgc
     9961 aaccgccttg atgcctcctc tttgtacagt aggttatgct attgcttctg ctaatctaaa
    10021 atttatcata ggctcctctt acctattcct catcaattgt agctttattg tcattgcgac
    10081 ttatataggt gttaggttga tgatggttaa gaaacattat tttaaagata acgaagaaga
    10141 ctctaaaatg cgtaggattt tgcttctagt tgctgttttg ctgatgattc cgagtttcat
    10201 ctctgcaacg actttagtga gagaaacgtt gaaaaaagag tcccttaaga aatttatatc
    10261 agagcagttt caggggtata atattttgaa aaaaacctat tctaaaaaga ctcataccct
    10321 aaagctaacc atttcaggaa attatttgac agaagaagaa ctcgatatga tttcaagtaa
    10381 gagaggtgac tatggtttaa gtgatgtttc tgttcaagtt tcacaattgt ctgattcaga
    10441 acaacttagt aaggaagagc tggtggagta tttcttccag tatatcaagg ataaggaagc
    10501 aaaagaaaag gagaaagcca ataaatttga tacagagtct gaggagcaat aatttcttga
    10561 gaatagctgg tttctctcgt gagtcttcta tgtatatcaa aggaagactg aggttttaag
    10621 tataaaactt ttcttctatt atagtagcta agtcttgaca gggttcaaaa aatggtttac
    10681 actttataaa gtttattact ttgaaaaggt gtgatactgt ggctacggca acaaaaaaga
    10741 aaaaatcaac agttaaaaaa aatctagtca tcgtggagtc gcctgctaag gccaagacga
    10801 ttgaaaaata tctaggcaga aactacaagg ttttagccag tgtcgggcat atccgtgatt
    10861 tgaagaaatc cagtatgtcc gtcgatattg aaaataatta tgaaccgcaa tatatcaata
    10921 tccgaggaaa aggccctctt atcaatgact tgaaaaaaga agctaaaaaa gctaataaag
    10981 tttttctcgc gagtgacccg gaccgtgaag gagaagcgat ttcttggcat ttggcccata
    11041 ttctcaactt ggatgaaaat gatgccaacc gtgtggtctt caatgaaatc accaaggatg
    11101 cagtcaaaaa tgcttttaaa gaacctcgta agatcgatat ggacttggtc gatgcccaac
    11161 aagctcgtcg gatcttggat cgcttggtag ggtattcgat ttcgcctatt ttgtggaaga
    11221 aggtcaagaa gggcttgtca gcaggtcgcg ttcagtccat tgcccttaaa ctcatcattg
    11281 accgtgaaaa tgaaatcaat gccttccagc cagaagaata ctggacagtt gatgctgtct
    11341 ttaaaaaggg aaccaaacaa tttcatgctt ccttctatgg agtagatggt aaaaagatga
    11401 aactgaccag caataacgaa gtcaaggaag tcttgtctcg tctgacgagt aaagactttt
    11461 cagtagatca ggtggataag aaagagcgta agcgcaatgc tcctttaccc tataccactt
    11521 catctatgca gatggatgct gccaataaaa tcaatttccg tactcgaaaa accatgatgg
    11581 ttgcccaaca gctctatgaa ggaattaata tcggttctgg tgttcaaggt ttgattacct
    11641 atatgcgtac cgattcgact cgtatcagtc ctgtagcgca aaatgaggcg gcaagcttca
    11701 ttacggatcg ttttggtagc aagtattcta agcacggtag caaggtcaaa aacgcatcag
    11761 gtgctcagga tgcccatgag gctattcgtc cgtcgagtgt ctttaataca ccagaaagca
    11821 tcgctaagta tctggacaag gatcagctca agctatatac ccttatctgg aatcgttttg
    11881 tggctagcca gatgacagcg gccgtttttg ataccatggc tgttaaattg tctcaaaatg
    11941 gagttcaatt tgctgccaat ggtagtcagg ttaagtttga tggttatctt gccatttata
    12001 atgattctga caagaataaa atgctaccag atatggctgt tggagatgtg gtcaaacagg
    12061 ttaatagcaa accagagcaa catttcaccc aaccgcctgc ccgttattct gaagcaacac
    12121 tgattaaaac cttagaggaa aatggggttg gacgtccatc aacctatgcg ccaaccattg
    12181 aaaccattca gaaacgttat tatgttcgcc tggcagccaa acgttttgaa ccgacagagt
    12241 tgggagaaat tgtcaataag ctcatcgttg aatatttccc agatatcgta aacgtgacct
    12301 tcacagctga aatggaaggt aaactggatg atgtcgaagt tggaaaagag cagtggcgac
    12361 gggtcattga tgccttttac aaaccattct ctaaagaagt tgccaaggct gaagaagaaa
    12421 tggaaaaaat ccagattaag gatgaaccag ctggatttga ctgtgaagtg tgtggcagtc
    12481 caatggtcat taaacttggt cgttttggta aattctacgc ttgtagcaat ttcccagatt
    12541 gccgtcatac ccaagcaatc gtgaaagaga ttggtgttga gtgtccaagc tgtcatcagg
    12601 gacaaattat tgagcgaaaa accaagcgta atcgcctttt ctatggttgc aatcgctatc
    12661 cagaatgtga atttacctct tgggacaagc ctgttggtcg tgactgtcca aaatgtggca
    12721 acttcctcat ggagaaaaaa gtccgtggtg gtggcaagca ggttgtttgt agcaaaggcg
    12781 actacgagga agaaaagatt aaataagagg aggggcccga aagtaaattt caggctcctt
    12841 ttggttagaa cttgacaaaa tacatcattt tatgcgaaac tagaagaaga ttattttaac
    12901 taggagaagt tatgcgtctt atctatctga taattggttt tttatcactg gccttggcta
    12961 ttgttggggt tgttttaccc ttgttgccga caacgccttt ccttttgttg tctattgctt
    13021 gtttctccag aagttccaag cgtttcgaag actggcttta tcataccaag ctctatcaaa
    13081 catatgtagc tgattttcgc gagactaagt ctattacgcg tgaacgaaag aaaaaaatca
    13141 tcgtctctat ctacgtcttg atgggaattt ctatttattt tgcacctctt ttaccagtca
    13201 aaatcggtct gggtgctttg accatcttta tcacttatta tcttttcaag gtcattccag
    13261 acaaagaata gttaaaacag tagttatttg ccttgataaa attgaaagca tattcataat
    13321 aatatgatat aataaatttg aagtaatatt caaggagaat caaatgattt acgaattttg
    13381 tgctgaaaat gtgactttac ttgaaaaagc gatgcaggct ggagctcgtc ggattgaact
    13441 ctgtgataat ctagcagttg gtgggacaac acccagctat ggagtgacta aggcagcggt
    13501 tgaactggca gctaactacg atacaaccat catgaccatg attcggccac gtggtggtga
    13561 ctttgtctat aatgacctag aaattgctat catgctagaa gacattcgtt tgactgctca
    13621 ggctggaagt caaggggttg tatttggaac tttaactgct gataaaaagt tggataagcc
    13681 taatctggaa aagttaattg ctgcatcaaa aggaatggaa attgtctttc acatggcctt
    13741 tgatgaacta agtgatgaag atcaaccgga agctattgac tggctcagtc aagccggtgt
    13801 cactcgtatc ctaactcgtg ctggtgtgtc tggcgactcc ttagaaaaac gttttgttca
    13861 ctatcacaga attttggagt acgctaaagg taaaattgaa attctaccag gtggggggat
    13921 tgaccttgaa aaccgtcaaa cctttatcga ccaggtgggg gtaacacaat tgcatggtac
    13981 taaggttgtt ttttaaaaaa tagaaaggaa ctgctagctt tgggtagcag ttttcactta
    14041 tgtttgaaat ttttaaatcc tatcaattta atcaagaaaa ggctcatgat tatggtttta
    14101 tagaaaatag cgaagtctgg acatatagtt gccagatttt gcaaggtgac tttgtcatga
    14161 ctgtgtccat cactgctgat aatgtgaact ttcaagtctt tgaccaagag actggtgacc
    14221 tctatcctca cgttcatatg gaaagcatga ggggaagttt tgtcggaaat gtccgtgagg
    14281 cttgtctgga gattctttac cagattcgga aggcttgttt tgatgtgcaa gattttatct
    14341 gtcatcagac taagcgtatc atgactcaag ttcaggaaaa gtatggaaac cagttggagt
    14401 atctgtggga aaaatcgcct gatacagctg tattgcgcca tgaaggcaat caaaagtggt
    14461 atgccgtctt gatgaaaatc tcttggaata agctggaaaa gggcagagaa ggacaagtgg
    14521 aagcagtcaa cctcaagcat gaccaagtag ctaatttgct ttcacaaaag gggatttatc
    14581 cagccttcca tatgagcaag cgctactgga ttagtgtgtc ccttgatgat actttatcag
    14641 atgaagaagt actggaattg atagaaaaaa gttggaactt aacctctaaa aaatgaaata
    14701 ttttaataat tttcatgaac tttcaattag ctaaatattc tttactgaag aaattttcag
    14761 aaaatatagg atttaccaca ccagaggaat atggtgccat cttcaaatac ctgattgaga
    14821 atgtcaagac ggatcgtcag atcatctatt cgcctcactg tcatgatgac ctcggaatag
    14881 cagtggcaaa tagccttgct gctgtcaaga atggtgcagg acgtgttgaa gagactatca
    14941 atggtattag ggagcgagct ggaaatgctg ctttggaaga aattgcagtg gctctcaata
    15001 ttcgccaaga ttactaccaa gtagaaacca gtattgtcct aactgagacc atcaatacgt
    15061 cagaaatggt ttctcgcttc tctggtattc cagttcctaa aaacaaagcc gtcgttggtg
    15121 gcaatacctt ctcccacgaa tctggtattc accaagatgg agtccttaaa aatcctctca
    15181 cttatgagat catcacacct gaattggttg gtgttaagat tccgcttgga aaattatctg
    15241 gtcgccatgc ttttgttgag aaactgagag aattggccct agattttaca gaagaggata
    15301 tcaaaccact ctttgctaag ttcaaggcac tggtcgataa gaagcaagaa atcacagatg
    15361 cagatattcg agctttggta gctggaacca tggttgaaaa tccagaaggc ttccactttg
    15421 atgatttaca acttcaaact catgcagata atgacattga agcgctcgtt agcctagcca
    15481 atatggatgg tgagaaagtc gaatttaatg cgacagggca aggttccgtt gaagcaatct
    15541 ttaatgctat cgataagttc tttaaccaat ctgttcgttt ggtgtcctac actatcgatg
    15601 cggtaacaga tggaatcgat acccaggaac gggttttggt cactgttgaa aacagagata
    15661 cagaaaccat cttgaatgca gcagggcttg attttgatgt gttgaaggct tctgctattg
    15721 cctatataaa cgctaatacc tttgttcaaa aagagaatgc aggtgagatg ggacgcagtg
    15781 tttcttacca cgatatgcct agtgtgtaaa ggagaaggct atggcaaaga aaatagtagc
    15841 tctagcagga gacggaattg gcccagaaat catggaggct ggtttagaag ttctggaggc
    15901 tctagctgaa aaaacaggtt ttgactatga gattgacaga cgaccgttcg gaggtgcaga
    15961 tattgatgca gcaggatctc ccttacctga tgaaaccctt aaggcaagta gggaagcaga
    16021 tgctatccta ctagtagcta tcggtagtcc tcagtatgat ggagtagcgg ttcgccctga
    16081 acaaggcctg atggctctcc gtaaggaact caatctttac gctaatattc gtcctgtaaa
    16141 aatctttgac agtctcaagt atttgtcacc actcaaaccg gaacgaattt ctggtgtaga
    16201 ctttgtcgtg gtgcgtgaat tgacaggcga gatttacttt ggagatcata ttcttgaaga
    16261 gcgcaaagcg cgtgatatca acgactatag ctatgaggaa gtggagcgga ttattcgcaa
    16321 agcctttgaa attgcaagaa atcgcagaaa aatcgttact agtatcgata agcaaaatgt
    16381 tctagcgacc tcaaaactct ggcggaaagt agctgaggaa gtcgcacagg atttcccaga
    16441 tgtaaccttg gaacaccagc tggtagactc agctgctatg cttatgatta ccaatcctgc
    16501 taagtttgat gttattgtaa cggagaatct ttttggagat attttatctg atgaatcaag
    16561 cgtcttatct ggtacacttg aggttatgcc atcagccagt cattctgaaa atggaccaag
    16621 tctctatgaa cctattcacg gttcagcacc tgatattgca ggtcaaggaa ttgccaatcc
    16681 tatttccatg attttattag ttgtcatgat gttgagagat agtttcggac gttatgagga
    16741 tacagagcgt atcaaacgtg ctgttgagac aagtctggcg gcaggaattt taacgagaga
    16801 tataggaggt caggcttcaa caaaggaaat gatggaagct attattgcaa ggttatgaag
    16861 ttagacgaaa aaattactct agtccttttg atttggaatg tcatcatttt cttgatttat
    16921 ggcattgaca aattcaaggc aagaagaaga gcttggcgca tcccagagaa aatcttactc
    16981 attttagccc ttacttgtgg tggttttggg gcctggttag ctggaatcac ttttcaccac
    17041 aagactcgaa aatggtactt taaaacagtt tggtttcttg ggatggtgac cacactagta
    17101 gccttatatt ttatttggag gtaatggatg gtagggtctt cgagggaaca cgctgcttgg
    17161 gctctagcgg actatggttt taaggtcgtg attgcaggat ctttcggtga cattcattac
    17221 aataatgaac tcaataatgg catgttgcca atcgttcagc ctagagaggt tagagagaaa
    17281 ctagcccagc taaaaccaac cgaccaggta actgtggact tggaacaaca aaaaatcatc
    17341 tcaccagttg aagaattcac cttcgagata gatagcaagt ggaaacataa actcctaaat
    17401 agtttggatg atatcggtat taccttgcag tatgaagagt tgattgctgc ttatgaaaaa
    17461 caacgaccag cctactggca ggattagaaa aaatagaaaa ggaaatatag taaactgaaa
    17521 taagatgtaa acaaatgaat tggagcttaa catccatttc cagcaatttt ttagaaacta
    17581 cagtggacta ttctggattc aacacattat aaaattatga caaaacacat tcacaagaag
    17641 gctacgacat tttaaaaggt gagggcggat gtatcgtttg ccctactaaa gttggttaca
    17701 ttatcatgac cagcaacaag gcaggacttg agcgtaagtt cgcagccaaa gaacgtaagc
    17761 gtaacaaacc aggtgttgtt ctctgcggta gcatggatga acttcgcgct ttagcgcaac
    17821 tcaacccaga aattgaagca ttctactaaa aacattggat gaagatattc ttcttggttg
    17881 tatccttcct tggaaaccag aagcctttga aaaactcaaa gcatacgggg atggccgtga
    17941 agaacttatg actgatgtac gtggtactag ctgttttgtt atcaagtttg gaaaagcagg
    18001 tgaacaattg gctgccaagc tttgggaaga aggtaaaatg gtctacgcct catatgcttc
    18061 aatgacaaaa cgattgaaac tcgctatgag agcaaggtgt aatggtgtct atggtcgata
    18121 aggacggcaa actcatccca gaacaaggag gagcacgttc aacttcacca gcaccagttg
    18181 tgatccgtaa agggcttgac attgataaaa tcatgatgca cctgtcagat acttttaact
    18241 catgggacta ctgtcaggtt gagtattatt aagataaaaa aagaagtcta gtgttatgag
    18301 atattaaagc tcctaacact ggactttttg tttagaattt cttttctttt tctataggat
    18361 atggt
//
LOCUS       DAVIME010000043        18139 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVIME010000043 DAVIME010000000
VERSION     DAVIME010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18139
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.043"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            55..351
                     /locus_tag="VV588_001600"
     CDS             55..351
                     /locus_tag="VV588_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU7083910.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDLVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            472..1416
                     /gene="manA"
                     /locus_tag="VV588_001601"
     CDS             472..1416
                     /gene="manA"
                     /locus_tag="VV588_001601"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU7083911.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(1437..2800)
                     /locus_tag="VV588_001602"
                     /pseudo
     CDS             complement(1437..2800)
                     /locus_tag="VV588_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821651.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3028..3777
                     /locus_tag="VV588_001603"
     CDS             3028..3777
                     /locus_tag="VV588_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU7083912.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3797..4252)
                     /locus_tag="VV588_001604"
     CDS             complement(3797..4252)
                     /locus_tag="VV588_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU7083913.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4272..5447)
                     /locus_tag="VV588_001605"
     CDS             complement(4272..5447)
                     /locus_tag="VV588_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU7083914.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5506..6351)
                     /locus_tag="VV588_001606"
     CDS             complement(5506..6351)
                     /locus_tag="VV588_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU7083915.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6476..7033
                     /locus_tag="VV588_001607"
     CDS             6476..7033
                     /locus_tag="VV588_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU7083916.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7052..7519
                     /locus_tag="VV588_001608"
     CDS             7052..7519
                     /locus_tag="VV588_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU7083917.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7608..8237
                     /gene="upp"
                     /locus_tag="VV588_001609"
     CDS             7608..8237
                     /gene="upp"
                     /locus_tag="VV588_001609"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU7083918.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8411..9001
                     /gene="clpP"
                     /locus_tag="VV588_001610"
     CDS             8411..9001
                     /gene="clpP"
                     /locus_tag="VV588_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU7083919.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9080..9328
                     /locus_tag="VV588_001611"
     CDS             9080..9328
                     /locus_tag="VV588_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU7083920.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9430..10590
                     /locus_tag="VV588_001612"
     CDS             9430..10590
                     /locus_tag="VV588_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU7083921.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDSLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10858..11727
                     /locus_tag="VV588_001613"
     CDS             10858..11727
                     /locus_tag="VV588_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU7083922.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11731..12687
                     /locus_tag="VV588_001614"
     CDS             11731..12687
                     /locus_tag="VV588_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU7083923.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12687..13451
                     /locus_tag="VV588_001615"
     CDS             12687..13451
                     /locus_tag="VV588_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083924.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13451..14161
                     /locus_tag="VV588_001616"
     CDS             13451..14161
                     /locus_tag="VV588_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083925.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14469..15125
                     /locus_tag="VV588_001617"
     CDS             14469..15125
                     /locus_tag="VV588_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU7083926.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIISL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15233..16328
                     /gene="prfB"
                     /locus_tag="VV588_001618"
     CDS             join(15233..15304,15306..16328)
                     /gene="prfB"
                     /locus_tag="VV588_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU7083927.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSYEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16346..17038
                     /gene="ftsE"
                     /locus_tag="VV588_001619"
     CDS             16346..17038
                     /gene="ftsE"
                     /locus_tag="VV588_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU7083928.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17031..17957
                     /locus_tag="VV588_001620"
     CDS             17031..17957
                     /locus_tag="VV588_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7083929.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT         5586 a         3422 c         3952 g         5179 t
ORIGIN      
        1 tataatgctt tttgatttta gtttagtatt atcgtagaaa atggactcgg tgctatggat
       61 acaccggatg agaatggtta tgtagcagat aactatcgga ttacttactt agaggcccac
      121 atcaaggcca tgcgagatgc catttaccaa gacggggttg acttgcttgg ttatacgact
      181 tggggctgta tcgatctggt ttcagctggc acaggggaaa tgaataagcg ctatggcttt
      241 atctatgtag atcgagataa tgtaggaaac ggagctctca aacgtagcaa gaagaagtcc
      301 ttctattggt acaaggatgt cattgatagc aatggtgcaa gcatcgggta gagcacattt
      361 gtttactatt tttataaaat cttctccctg ctttataaga tgtaaaaaag agttcaattc
      421 gaactctttt tttgctataa tgaggggaga aaaatcagac aggagatcga catgtcagaa
      481 ccattatttt tacaatcagt tatgcaagaa aaaatctggg gtggagccaa gctacgtgat
      541 gagtttggct acgacatccc aagtgaaaaa atcggagaat attgggccat ctcagcccat
      601 ccaaatggag tctctaaagt tgccaatggt cgttacgagg gaacagatct tgctactttg
      661 tatgcggaac accgtgaatt atttggcaat cgtccagaac ctgtatttcc acttttgacc
      721 aagatcctcg atgccaacga ctggctcagt gtccaagttc acccagacga tgcttatgga
      781 ctcgagcatg aaggcgaact cggaaaaaca gaatgctggt acattatcgc agcggatgaa
      841 ggttcagaga ttatctacgg tcacaatgcc aagtcaaaag aagaactccg ccagcaaatc
      901 gaggataaga actgggatgc gctgttgaca aaagtgccag ttaaagcagg agatttcttc
      961 tatgtaccaa gcggtaccat gcacgctatc ggggcgggta tcttgattct tgaaacccag
     1021 cagtctagcg ataccactta ccgtgtctat gactttgacc gaaaggacga taagggcaac
     1081 ttgcgtgaac ttcaccttga aaaatctatc gatgtcttga acattggtga acccgcaaat
     1141 agccgtccag tgacaatcaa agcagatgat ctacgttcca ctctccttgt atccaatgat
     1201 ttcttcgcag tttacaaatg ggaaattact ggaaaagtta actttgaaaa gacagctgac
     1261 tacagcttgt tgagtgtctt ggctggtcaa ggtcaactaa ctgttgacgg gaaaaactat
     1321 ccaatccaaa aagggagaca ctttatccta ccaagtgatg ttgaatcttg gactttagaa
     1381 gggcaagatt tggaattgat tgttagtcat ccataaaaag aaagggcctg agttcactac
     1441 tcaagtcctt tttgattaca taaattgggc gatgaagacc acgatgatga ttggaatgac
     1501 gaaacgaaga aacgaaggag gaagagccag acttggaaaa gtacttgttt ccaggctctt
     1561 tcatcgagat ggagttcctc cataacaaga gcctttttaa agatatagcc tgtaaaaagt
     1621 gaaaggcaga gagctccaaa tggcatgaga agattggaaa ccaagaaatc catggcatca
     1681 aagaaagtct taccaaagat gtgaacatcc gccataactc cataggatag ggctgaagga
     1741 atgccaaaga caaaggtcaa aattcctaaa ataacactcc atttggcacg tttgctgtta
     1801 tcctggttgg tgatattgcc cacattgatc tccagcatca cgacagaaaa agtgactggc
     1861 gcaaaaagga agagcaagag gaaaaggacg tagaaaatgg ttccaaaagg catcttgtca
     1921 aagagttgag gcaagacgat aaagagcaag ctcggtcccc cttcagactg gatattgaag
     1981 ggggaccgag cttggaaaat ggctagacct gccatgatgg atatcgagat attcatggct
     2041 acgatggaga ttcctgactg gactaggttg gttttcttgt ccaagtaaga agcataggtc
     2101 aacatgactg taacccctag tgagagggca aagaaagatt gtcccagagc atagaggaga
     2161 ccagcgctag tcagttttga aaagtctggt ttgaggaagt aaagaacccc ttccatggca
     2221 tttggcaaac tgagagagcg accgatgata acaacaaaga tgataaagag caggggcatc
     2281 atgactttcg aagctctttc aatccctttt tgaaccccac gtgatacaat aaagatattt
     2341 aataagataa aggctgcttg agctcctagg gcaatggctg gatttgaaat gattgaagta
     2401 aataactgag cataatcacc cgttccacca agttggaaca atttcccaaa ctcaatacct
     2461 agatagacta gaatccatcc tccgataaca ctgtaaaaag ataagaggat aaagagggca
     2521 aaggcgccaa tccaaccgat aaagttgtac ttgttattct tgcccagttt tccaaaggtt
     2581 ttgatagcgg aaacgccagc actacggcca agggcaaact cagccagcag gagagggaaa
     2641 ccgattaaaa tagtggaaat gagaaagatt agtaaaaagc ctccatcgcc attagcagca
     2701 gtcatgtagg gaaacttcca aacggaacca agcccgatgg ccagccagca gatgctagaa
     2761 taaaaccaag tttcgacccc cattgtgatt tttctgacat agttaaactc tgatctcctt
     2821 tttcaaaata agaaaaagct acttgagttg tcaaatagcc ttctgtttga ttgatagact
     2881 tgactatcct atcatgtttt ctaaggtctg tcaagaaaat cattttcaag ttttcacacc
     2941 tttctcaaaa aagttaaaaa attttctcaa aaacgcttga ctctgaccta aggggagggg
     3001 ttatactatc attgtaagga ggaaatcatg taccatataa aagaagctgc gcagctttca
     3061 ggtgtctctg tcaagaccct gcatcactat gacaagatag gactcttggt ccccttaaag
     3121 tcggaaaacg gctatcgaac ctacagtcaa gaggatttgg aacgccttca ggtcattctt
     3181 tactacaaat atctaggctt ttctttagag aaaatagcag agctgttaaa ggaagaaagg
     3241 acagatttat tgccccattt gactaggcag ttggactatc taactcgcga aaggcaacat
     3301 ctggatacct tgatttccac cttgcaaaaa actattcaag aacaaaaagg agaaagaaaa
     3361 atgaccattg aggaaaaatt cacgggattt agctatcaag acaatcaaaa ataccaccaa
     3421 gaagcggtag agaaatatgg tcaagaagtc atgggacaag cgctcgaacg ccaaaaaggt
     3481 cacgaagacg aggctacggc cgcctttaac caagtctttc aaactttggc acaaaatctt
     3541 caagttggtt tacctgcaac agcaaccgaa aaccaagagc aagcagccaa gctcttgcaa
     3601 gccattcgca cttatggatt tgactgctct attgaggtat tcggtcatat cggtaaaggt
     3661 tacgtctata acccagagtt taaggaaaac attgacaagt ttggttctgg aacagcccag
     3721 tacacgtcag atgccattgc agcttacgtt cagacaaatg cagaaaaaat aggctaggaa
     3781 tttcctagcc tattttttac ttcaaatcat aaagccagtc gtcaccgttt ttgtagtaaa
     3841 agaattcact gagatcttct tctagaaaca cacgaagcat atcagacata tcatcggttg
     3901 caagttttag atgagaaaga ttttcaaagt cctcccacca aactttccct tcgtctgaag
     3961 actggagttc accagtaaag tgttctgtct tgtaaaaaag gacgacataa cgataatcct
     4021 tgtcgtcata ccagtttttg ataccacaga gttggggttt ggaaatgatc agaccagttt
     4081 cttctttcac ttcacgaatg acagcatcga caaaggattc gccacgttca acatgaccac
     4141 caggaaaagt aatgccaggc cagtcgggac taactcggtc ttggaccagg accttatctc
     4201 cgtttttaat catacacatg ttaacaaatt cgactgcctc tcttctgttc attcttcaca
     4261 acctttaatc tttaatcata atgcagactt cccgccaccc agccggtaca gagggcagaa
     4321 gtgatgttaa agccacccgt gtgggcattg atatccataa cttcgcctgc aaagtggagg
     4381 ccaggtacca gcttactttc aagggtttta ggattgattt ccttgagact gactccaccc
     4441 ttggtaacaa aggactttgc aagggacatt tttccagtta caggaatttt aagttcttta
     4501 atggactgga caagctgttc tcgttccttt tcagtcagct gtttgacttt ttcaggatat
     4561 ccttgtacaa aaaattcggc caagcgttct ggtaacaagg tttttaaagc gtttttcaag
     4621 gatttttccc gattttcttc tagaaatgta accaagtcct tctcagaaag ttgaggcaaa
     4681 acatcgagtg agagaacctc cccacctttg acaaagctag acatgcgtag ggcagcagga
     4741 cctgacaaac caaagtgggt aaagagtaaa tcatgagtga tgacatgctt accataactt
     4801 agggtcacat cgtccaaaga aatcccttgt aaggctttat gtggaaaatc tgttaataaa
     4861 ggactttcag cagcctcaag atcggtgatg gtatgcttaa aatggcgagc aatctcgtga
     4921 ccaaaaccag tcgaaccagt cgaaggataa gacttaccac ctgttgtgac aatgagtttc
     4981 tcacaagtga aggtttgatc cgctgactta aggacaaact ggttatctac ttttttaaca
     5041 gaaacgattt ctatttgagt agcaacttga ccacctagtt cggtgatttt cttttccaaa
     5101 gcttcgataa tagtccgaga cttgtcactg gctggaaaga cgcgtccgtg gtcttcgacc
     5161 ttaagtttaa caccattttc tgtaaaaaag ttgatgatgt catgattatc gaactgggag
     5221 aaaacactgt aaagaaagcg tccgtttcca ggaattccag ctagcaggtt gtctaagcta
     5281 ccattgttgg tcacattgca acgtccccca ccagtcccag ctaatttttt tccaagtttc
     5341 cgattttttt cgatgaggag ggttttctgt ccataaaagc tactggaaat cgtagccatc
     5401 ataccagcag gtcccccacc gatgacaata gtatcaaaat gtttcatagc tctattgtac
     5461 cacaaaaaaa caagagatga tggtcacctc ttgtcaagaa tgcaattaat caatttcata
     5521 gcccatcagc aaaccgccct cttctgcata gaaactgcag agaccagagg ttggtagaat
     5581 tttaatatcc gcttgtggga aggtttcacg gattcgctct gagagctgtt gacaacattt
     5641 ttcgttattg cgttgggcca tgacaatacg gccaccagca tatccagctt ttactaactc
     5701 atcataggca gcttgaactg atttctttga tccccttgct ttttgtagca attcgagagt
     5761 cccagtttca ctagcttttc cgaccatacg aatgttgaga aggccaacga ccgtaccgat
     5821 aagcttgctc aaacggccgt tcttcaccaa gttatcgact ttggctagga caaagagcaa
     5881 cttagttttt tcttgatagg cggtgatagc ttcaaccact tcttcaaaag acaagccctg
     5941 gtcaatcaag tcattcaatt tttctacgag taggtcaact tcaccaccag cagataaact
     6001 atcaatcaca tgaatcttag tgtcaggatg gtcttccaga taaatattct ttgctagttg
     6061 agcactattg tgactgccag aaagggtacc tgtgatggtt actaggaaaa tgtttttggc
     6121 accttcaaat gctcgcaaat agtcatctgg gcttggacaa gctgattttg aagcttctgc
     6181 agttgcatac atggtttcca tcatttggtc aatatcgaga ctggcgtcat caacaaagac
     6241 ctgatcagct acttgaatgg ttaaggggac acttacaaag gttgtgttaa tagctggtgt
     6301 tggcagttga cgataatcac aaccagagtc agcaataatc ttccaagtca tagaaattct
     6361 ccatctttgt cagttataca ttgacaaagg ttctgtcttt ttttacaatt atatcatgaa
     6421 aactcttgaa acaaaagcat catccgtctg ttgtgacaag tagaaagaaa atgttatgtc
     6481 tgaacgtaga atctctgaaa agtctcttga aaatctcaga aaatcaaatc aagaatccaa
     6541 tttattaacc agagaagcca ttgaaacagc cctcttgcaa ctcttggaaa aaaaggagct
     6601 gaccaagatt agtatttctg aattggtcaa acgtgcaggt gtttcgcgtg cggcctttta
     6661 tcgcaattat gactccaaag aggaaatttt agagagcgtc tttaaacgaa ctgtccacaa
     6721 tattatggaa cagctgcatc attacgattt aaagacagac ctttatttgg tttgggttca
     6781 ccttttccgg gaggccagaa aggaagctag agtaattcaa ttggccttgg attaccatct
     6841 ggaaaaaatc tttgtccaag ccatgcagga atttctagaa aaataccatg ggaaatcaaa
     6901 aggtgtcagc tcttatcttc attccttctg gagctcagcc atcgtctctg tccttctaaa
     6961 atggatcaag gatggcatga aggtaccagc tgaaaagatt gcagatttag gtttaccatt
     7021 ttttaaaaaa tagagaaaaa ggagaaaaga gatgactgaa aaaagactgg cctgggatga
     7081 gtattttgca gcccaagccc tactaattgc gaatcgttcc acttgtaaac gtgctaaagt
     7141 gggcgcgatt ctggtaaaag ataataaggt tatttccact ggttacaatg gttcggtgtc
     7201 agggactgag cattgtattg atcacgaatg tttggtcatt gaaggccact gtgttcgcac
     7261 ccttcacgct gaggtcaatg ctatccttca aggtgctgag cgtggtgttc ccaaaggctt
     7321 tacagcctat gtaacccatt ttccttgtct caactgtaca aaacaattgc ttcaggtcgg
     7381 ctgcaagcgc gtggtttata tcaaccagta ccgaatggac gactacgccc aataccttta
     7441 tcaagaaaaa gggacagaat tgacccattt accacttgag acagtacaga cagctcttaa
     7501 agaggctgat ctaatgtaaa aattatcaaa aataaatggt ttagaaagat ttttaaaccg
     7561 ttttttggta taatgagaag aataaattga aagaaggaat tccaaaaatg ggaaaaattg
     7621 aagttattaa tcacccactg attcaacaca aattgtcaat cttgcgtcgt acagatactt
     7681 ctacaaaagc ttttcgtgag ctagtagatg agattgcaat gttgatgggg tatgaagtac
     7741 ttcgtgatct tccactagaa gatgtggaaa tcgaaacacc aattacaaaa acagttcaaa
     7801 aacaattggc aggtaagaaa ttggccatcg tcccaatctt gcgtgcaggt atcgggatgg
     7861 ttgatggtct cttgagcttg gttccagctg ctaaagttgg ccacatcggt atgtaccgtg
     7921 atgaagaaac acttcaacca gttgaatact tggtgaaatt gcctgaggac attgaccaac
     7981 gtcaaatttt tgtagtagac ccaatgttgg caacaggtgg ctcagcaatc ttggctgttg
     8041 attctcttaa aaaacgtggc gcatcaaata tcaaatttgt ctgccttgta tctgctccag
     8101 agggtgtaaa agcccttcaa gaagctcatc cagatgtaga aatctttaca gcagccttgg
     8161 atgaacgttt gaacgaacac ggttatatcg ttccaggtct tggagatgct ggagaccgct
     8221 tgttcggtac aaaataagat cgaaaagaag aatgacttgg aaaagtattt ccagtcacga
     8281 aaggaggttg ggtttttgtt tctgtctaat gaaagcagag caaaaatttg accttttttg
     8341 accaagatat tataatagtc ttatcttcag tcatttgacc aacaaaatta aaactcaaaa
     8401 ggagaaatga atgattcctg tagttattga acaaacaagc cgtggagaac gttcttacga
     8461 tatttactca cgtcttctca aagaccgcat cattatgctg acaggtccgg ttgaagacaa
     8521 tatggctaac tctgttattg cccaattgct tttcttggat gcccaagata gtacaaaaga
     8581 tatttacctt tatgtcaata caccaggtgg ttctgtttca gctggtttgg caatcgtaga
     8641 taccatgaac tttatcaagg cagatgtcca aaccattgtt atgggaatgg ctgcatctat
     8701 gggaacagtc atcgcatcaa gtggagcaaa aggcaaacgt ttcatgcttc caaatgctga
     8761 atacatgatt catcaaccaa tgggcggtac aggtggtggt acccaacaaa ctgatatggc
     8821 tatcgctgca gaacacttgc tcaaaactcg taataccttg gaaaaaatct tggctgaaaa
     8881 ttcaggtcag tcaatggaaa aagtccatgc agatgcagaa cgtgataact ggatgagcgc
     8941 ccaggaaaca cttgaatatg gctttattga tgaaattatg gccaacaatt cattgaacta
     9001 atgatgatag aaggcaaact cgactgggtt tgcttttttt ggtataatag ggagagattt
     9061 cttagaaaga ggatttatca tgtttgaaaa agtcaatcgc tctggcttga ttatctatct
     9121 ttactataat cgtgatgcca aaaaactgca ggattatgga gatattacct atcattccaa
     9181 gaaacatcgt tacttacaac tctatgttcc aactcaagaa gtggagcaat tggtcggacg
     9241 cttgagcaag gaaaaattta ttaaaaaagt tagagtttgt catatccaag agttggaaac
     9301 accctttgtg ggcaatcttt atcgatagga aaacgttatc atcgaaaaag ttcaaggaaa
     9361 acattgacaa ttttctgata attcggtata ttcttaacag actatttaag aaataaggag
     9421 acaaaaaaga tgaagaaaaa atttgcccta tcgtttgtgg cgcttgcaag tgtagcactt
     9481 cttgcagcct gtggagaagt gaagtctgga gcagtcaaca ctgctggtaa ctcagtagag
     9541 gaaaagacaa ttaaaatcgg gtttaacttt gaagaatcag gttctttagc tgcatacgga
     9601 acagctgaac aaaaaggtgc ccaattggct gttgatgaaa tcaatgccgc aggtggtatc
     9661 gatggaaaac aaatcgaagt agtcgataaa gataataagt ctgaaacagc tgaggctgct
     9721 tcagttacaa ctaaccttgt aacccaatct aaagtatcag cagtcgtagg acctgcgaca
     9781 tctggtgcga ctgcagctgc ggtagcgaac gctacaaaag caggtgttcc cttgatctca
     9841 ccaagtgcga ctcaagatgg attgactaaa ggtcaagatt acctctttat tggaactttc
     9901 caagatagct tccaaggaaa aattatctca aactatgttt ctgaaaaatt aaatgctaag
     9961 aaagttgttc tttacactga caatgccagt gactatgcta aagggattgc caaatctttc
    10021 cgcgagtcat acaagggtga aatcgttgca gatgaaactt tcgtagcagg tgacacagac
    10081 ttccaagcag cccttacaaa aatgaaaggg aaagactttg atgctatcgt tgttcctggt
    10141 tactataatg aggctggtaa gattgtaaac caagcgcgtg gcatgggaat tgacaaacca
    10201 atcgttggtg gtgatggatt caacggtgag gagtttgtac aacaagcaac tgctgaaaaa
    10261 gcatcaaaca tctactttat ctcaggcttc tcaactactg tagaagtttc agctaaagct
    10321 aaagccttcc ttgacgctta ccgtgctaag tacaatgaag agccttcaac atttgcagcc
    10381 ttggcttatg attcagttca ccttgtagca aacgcagcaa aaggtgctaa aaattcaggt
    10441 gaaatcaagg atagccttgc taaaacaaaa gattttgaag gtgtaactgg tcaaacaagc
    10501 ttcgatgcag accacaacac agtcaaaact gcttacatga tgaccatgaa caatggtaaa
    10561 gttgaagcag cagaagttgt aaaaccataa tagaaaaatg ttgaaatagg gaatgagcct
    10621 ttgactcact ccctgtttcg atatttaata ctcttcgaaa atctcttcaa actgcgtcaa
    10681 cgtcgccttg gattatatat gtgactgact tcgtcagtct tatctacaac ctcaaagcag
    10741 tgctttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtataag
    10801 aacctatcaa aaagtgaggg aaaaccctcg gaattataaa tagaaagagt gaatcttatg
    10861 ctccaacaac tcgtaaatgg tttgattcta ggtagtgttt acgcgctgtt agccctagga
    10921 tataccatgg tttacggaat tatcaagctc atcaacttcg cccatggtga tatttatatg
    10981 atgggagcct ttatcggtta tttcttgatc aattctttcc aaatgaattt ctttgtagcg
    11041 cttattgtag ctatgctagc gacagctatt cttggtgtcg tgattgagtt tcttgcttac
    11101 cgacctttgc gccactctac tcgtattgct gttttgatta cggctattgg ggtttctttc
    11161 ctattggagt atggaatggt ctatctggtt ggtgccaata cccgtgcctt ccctcaagcg
    11221 attcaaacag ttcgatatga tttgggacca attagcttaa caaatgtgca gttaatgatt
    11281 ttggccattt ccttgatttt gatgattttg ttacaagtca ttgtccaaaa gactaagatg
    11341 gggaaagcca tgcgtgcagt atcagtagat agcgacgcgg cgcaattgat ggggatcaat
    11401 gtaaaccgta cgattagctt taccttcgct ttgggttctg ctcttgcggg tgcggctggt
    11461 gttctgattg ctctttatta taactctctt gagcctttga tgggggttac tccaggtctt
    11521 aaatctttcg ttgccgcagt acttggtggt atcggaatta ttcctggtgc ggctcttggt
    11581 ggctttgtga ttggtctatt ggaaaccttt gcgacagcct ttgggatgtc agatttccgt
    11641 gatgccattg tttatggaat cttgttgttg atcttgattg tccgcccagc tggtatcctt
    11701 ggtaagaatg tgaaagagaa ggtgtaaacg atgaaggaaa atttaaaagt taatattcta
    11761 tggttactcc ttttgttagc tggctatagc ttgattagtg tactggtttc agtcggagta
    11821 cttaatctat tctatgtaca gattttacaa caaattggaa ttaatattat tttggctgtt
    11881 ggtctcaact taatcgttgg tttttcagga caattttcac ttggtcatgc tggtttcatg
    11941 gcgattggtg cctatgcagc agctattatt ggttctaaat caccaaccta cggtgccttc
    12001 tttggagcta tgcttgtagg ggctttgctt tcaggagcag ttgccttact tgtcggcatt
    12061 ccaaccttgc gcttgaaggg ggactatctt gcggtagcaa ctctgggtgt ttctgaaatt
    12121 atccgtatct ttatcatcaa tggtggaagt cttacaaatg gtgcggcagg tatcttaggg
    12181 attcctaact ttacaacttg gcaaatggtt tacttctttg tcgtgattac aaccattgca
    12241 accttgaact tcttgcgtag cccaattggc cgttcaaccc tctctgttcg tgaagatgaa
    12301 atcgctgctg agtcagttgg ggttaatacg actaaaatta aaatcatcgc ttttgtcttt
    12361 ggtgccatta ctgcaagtat tgctgggtca cttcaggcag gatttatcgg gtctgttgta
    12421 ccgaaagatt acaccttcat caactcaatc aacgttttga ttattgttgt atttggtgga
    12481 ctcggttcca ttacaggtgc gattgtttcg gctattgttc tgggaatttt gaatatgctt
    12541 ctccaagatg ttgctagtgt gcgtatgatt atttacgctt tggccttggt attggtaatg
    12601 attttcagac caggtggact ccttggaacg tgggaactga gcctatcacg tttctttaaa
    12661 aaatctaaga aggaggaaca aaactaatgg cattacttga agtaaaacag ttaaccaaac
    12721 attttggtgg tctaacagct gttggagatg tgactcttga attgaacgaa ggggaactgg
    12781 ttggattaat cggtccaaac ggagctggga aaaccaccct tttcaacctt ttgaccggtg
    12841 tttatgaacc aagcgaggga acagtaaccc tagatggtca ccttttgaat gggaaatcac
    12901 cttataagat tgcctctttg ggacttggac gtactttcca aaatatccgt ctttttaaag
    12961 atttaacagt tttagacaat gttttgattg cttttggaaa ccatcacaaa cagcatgttt
    13021 ttactagttt cttacgctta ccagcttttt acaagagtga aaaagaatta aaggctaaag
    13081 ctttggaatt gttgaaaatc tttgatttag atggtgatgc agagactctt gctaaaaatc
    13141 tttcctacgg acaacaacgt cgtttggaaa ttgttcgtgc ccttgctacg gaacctaaaa
    13201 ttctcttctt agatgaacca gcagcaggta tgaacccaca ggaaacagcc gaattgactg
    13261 agttaattcg tcgtatcaaa gatgaattta agattacaat catgttgatt gaacacgata
    13321 tgaatctggt catggaagta acagaacgta tctacgtact tgaatatggc cgtttaattg
    13381 ctcaaggaac tccagacgaa attaagacca ataaacgcgt tatcgaagct tatctaggag
    13441 gtgaagccta atgtctatgt taaaagttga aaatctttct gtgcattacg gtatgatcca
    13501 agcagtccgt gatgtaagct ttgaagttaa tgaaggagaa gttgtttccc ttatcggtgc
    13561 caacggtgca ggtaagacaa ctattcttcg caccttgtca ggtttggttc gaccaagttc
    13621 aggaaagatt gaatttttag gtcaagaaat ccaaaaaatg ccagctcaga aaatcgtggc
    13681 aggtggtctt tcacaagttc cagaaggacg ccacgtcttt cctggcttga ctgttatgga
    13741 aaatcttgaa atgggagctt tcttaaagaa aaatcgtgaa gaaaatcaag ctaacttgaa
    13801 gaaggttttc tcacgctttc ctcgtcttga agaacggaag aaccaagatg cagctactct
    13861 ttcaggaggg gaacaacaaa tgcttgccat gggacgcgct cttatgtcaa caccaaaact
    13921 tcttctttta gatgaaccat caatgggact tgccccaatc ttcatccaag agatttttga
    13981 tatcattcaa gatattcaga agcaaggaac aaccgtcctc ttgattgaac aaaatgccaa
    14041 taaagcactc gcaatctctg accgaggata tgtattggaa acaggaaaaa tcgtcctatc
    14101 agggacagga aaagaactcg cttcatcaga agaagtcaga aaagcatatc taggtggcta
    14161 aaacaatcca gtggattgtt ttagtcggca gatgaagatt acgaagtaat catcaatata
    14221 gtccggggga cctttttagc cggtagattg agattgcaaa caaatctgca tctacattga
    14281 aagcttaatt tctaataatt gaaaaaatcg aatgaaaagt ttcttacctt cattcacaga
    14341 gctcgatttt agagctcttt ttgctagctt attcatactt ttctaaattt tgaaaaagaa
    14401 atgtaagcgt ttgatagatt tgcaaaaaga ttgtataata gggataagaa tagaaaagga
    14461 gaagtctcat ggcagttaaa gattttatga cccgcaaggt agtttatatt agtccagata
    14521 caacagtatc tcatgcagca gatttgatga gagagcaagg attgcaccgc ttgcctgtta
    14581 tcgaaaatga tcaattggtt ggtttggtga ctgagggaac cattgcacaa gcaagtccat
    14641 ctaaagcaac aagtctttct atctatgaga tgaattatct tctgaataag acaaaagtaa
    14701 aagatgtcat gattcgcgat gttgtcactg tctcaggcta tgctagtcta gaagatgcaa
    14761 cttatctgat gttgaaaaat aagattggta ttctccctgt cgtagataac catcaagtat
    14821 acggagttat tactgaccgt gacgttttcc aagcctttct tgaaattgca ggttatggcg
    14881 aagaagggat tcgtgtacgc tttgttacag aagatgaagt tggtgttctt ggaaaaatta
    14941 tttctttgat tgtagaagaa aatttgaata tctcccatac agtcaatatt ccgcgtaagg
    15001 atggtaaggt cattatcgaa gtgcaaatcg atggatcaat tgatttacca gccttgaaag
    15061 aaaaatttga agcaaatggt attcaagtgg aagaaatcgc tcgcacttca gcaaaagtct
    15121 tgtaagaagg gaagcccaaa ggcttctttt ttcatgaaaa ggggattaga gcaaaagatg
    15181 gaaagaaatg ataaaatatg ctataatgaa atgatgtaaa aaaggagtat ttatggacat
    15241 ttcagtaatt cgtcagaaaa ttgacgcaaa tcgtgaaaaa ttagcttctt tcagggggtc
    15301 tctttgacct cgaagggcta gaggaagaga ttgccatctt ggaaaacaag atgacagaac
    15361 ctgatttttg gaacgataat attgcggccc aaaaaacgtc gcaagaattg aatgaattaa
    15421 aaaacactta caataccttc cataagatgg aagagttgca ggatgaagtc gaaattttat
    15481 tggatttttt ggctgaagac gagtcagtgc atgatgaact ggtagcgcag ttagccgaac
    15541 ttgataagat aatgaccagc tacgagatga ctctactctt gtcagaacct tatgaccaca
    15601 acaatgccat cttggaaatc catccaggtt ctggtggtac tgaggcgcag gactggggtg
    15661 atatgttgct tcgtatgtat actcgttatg gtaatgctaa aggctttaaa gtggaagtgt
    15721 tggattacca agcaggtgat gaggctggta ttaagtcggt aactttatca tttgaagggc
    15781 ctaatgccta tggtctcctc aagtcagaaa tgggtgttca tcgcttagtg cgaatctcac
    15841 catttgactc tgccaaacgt cgccatacct ctttcacatc tgtagaagtg atgccagaat
    15901 tggatgatac tattgaagtg gaaatccgtg aagatgatat caagatggat accttccgtt
    15961 caggtggtgc cggtggacaa aacgtcaata aggtttcaac aggtgtacgt ttaacccaca
    16021 ttccaactgg aattgttgtc caatcaacag tggatcgtac ccagtatgga aatagagatc
    16081 gcgccatgaa gatgttgcag gctaagctct atcaaatgga gcaagagaag aaggctgcgg
    16141 aggtagattc tctcaaaggt gagaaaaagg agatcacttg gggaagtcaa atccgttctt
    16201 atgtcttcac gccttatact atggtaaaag atcaccgaac tagctatgag gttgctcagg
    16261 tagataaggt tatggatggg gacctagatg gttttatcga tgcttatctc aagtggcgaa
    16321 ttagctaaga tagaaaggaa ctcacatgtc aattattgaa atgagagatg tcgttaaaaa
    16381 atacgacaac ggaacgactg ctctacgcgg tgtttcggtt agcgttcaac cgggggaatt
    16441 tgcttacatc gtaggacctt caggagcagg gaagtcaact tttattcgtt ctctgtatcg
    16501 tgaagtaaaa atcgataaag gaagtctatc agttgctggt tttaatctgg ttaagatcaa
    16561 aaagaaagat gtcccgcttc tacgtcgtag tgttggggtt gtcttccaag attataaact
    16621 gttaccaaag aaaactgtct atgaaaatat tgcttacgct atggaagtaa tcggggaaaa
    16681 tcgccgtaat atcaaaagac gagtgatgga agttttggac ttggttggat tgaagcataa
    16741 ggttcgttct ttcccaaatg aactctcagg tggggagcaa cagcggattg cgattgcgcg
    16801 tgcaattgta aataatccca aagtattgat agctgatgag ccaacaggaa atctggatcc
    16861 ggataattca tgggaaatta tgaatctctt ggaacggatt aacctacaag gaacaactat
    16921 tttgatggcg actcataata gccagattgt aaataccttg cgccaccgtg tcattgccat
    16981 tgaaaatggc cgtgtcgttc gtgacgaatc aaaaggagag tatggatacg atgattagta
    17041 gattttttcg ccatttattt gaagccttaa aaagtttgaa acgaaatggt tggatgacag
    17101 tagctgctgt cagttcagtc atgattactt tgaccttggt ggcaatattt gcatctgtta
    17161 ttttcaatac agcgaaacta gctacagata ttgaaaataa tgtccgtgta gtagtttata
    17221 tccgaaagga tgtggaagat aatagtcaga caattgaaaa agaaggtcaa actgttacaa
    17281 ataatgacta ccacaaggta tatgattctt tgaagaacat gtctacggtt aaaagtgtta
    17341 ccttttcaag taaagaagaa caatatgaaa aattaaccga gataatggga gataactgga
    17401 aaatctttga aggagatgcc aatcctctct atgatgccta tattgtagag gcaaacactc
    17461 caaatgatgt aaaaactata gccgaagatg ctaaaaaaat tgaaggtgtc tctgaggttc
    17521 aagatggcgg tgccaataca gaaagactct tcaagttagc ttcatttatc cgtgtttggg
    17581 gactagggat tgctgctttg ttaattttta tcgcagtttt cttgatttca aataccattc
    17641 gtattaccat tatttcccgc agtcgcgaaa ttcaaatcat gcgcttggtc ggagctaaaa
    17701 acagttatat ccgtggaccg ttcttgttag aaggagcctt tatcggttta ttgggagcta
    17761 tcgcaccatc tgttttggtc tttattgttt atcaaattgt ttaccaatct gtcaacaaat
    17821 cgttggtagg gcaaaatcta tccatgatta gtccagattt atttagtccg ttgatgattg
    17881 ccctactatt tgtgattggg gttttcattg gttcattggg atcaggaata tccatgcgcc
    17941 gattcttgaa gatttaggta aaatagctgc ttttatgagg agattgtaaa atctcctttt
    18001 ttgctacaag agtttttgaa aagagatgcg cagaagaaaa gagcttccaa agaagtcccc
    18061 cagagaagac ttcttgatgg ctaatttgaa cttgaaattt ggcgcactag aaatttttta
    18121 gaaaaaagtg taatttttt
//
LOCUS       DAVIME010000044        17698 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVIME010000044 DAVIME010000000
VERSION     DAVIME010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.044"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..980
                     /locus_tag="VV588_001621"
     CDS             <1..980
                     /locus_tag="VV588_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU7083930.1"
                     /translation="RKNRITLFSSLFLLIIISLSFFILLIGDESYSFSTLIKVLNSET
                     VPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIGVTSSSSIAAV
                     FCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIGFQAVTRAGTS
                     FLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFNKRLEIIELGE
                     EIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALNIGKKRSPILA
                     GLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRNI"
     gene            980..1774
                     /locus_tag="VV588_001622"
     CDS             980..1774
                     /locus_tag="VV588_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083931.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            2162..2587
                     /locus_tag="VV588_001623"
     CDS             2162..2587
                     /locus_tag="VV588_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU7083932.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            2643..2960
                     /locus_tag="VV588_001624"
     CDS             2643..2960
                     /locus_tag="VV588_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU7083933.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            3270..4490
                     /locus_tag="VV588_001625"
     CDS             3270..4490
                     /locus_tag="VV588_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU7083934.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDKSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKEKESIQKQIKKYK
                     DLSKNKDKTKEKGK"
     gene            4664..5386
                     /locus_tag="VV588_001626"
     CDS             4664..5386
                     /locus_tag="VV588_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU7083935.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEKDIEIDKEREGEIDKKSTP
                     IFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEE
                     DKDKLRQKGLNKKMNYDVGESL"
     gene            6070..6231
                     /locus_tag="VV588_001627"
     CDS             6070..6231
                     /locus_tag="VV588_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083936.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQDMKNSFD
                     MAKTQIETD"
     gene            6323..8002
                     /locus_tag="VV588_001628"
     CDS             6323..8002
                     /locus_tag="VV588_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU7083937.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSDKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIIEELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYKEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            8270..8836
                     /locus_tag="VV588_001629"
     CDS             8270..8836
                     /locus_tag="VV588_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083938.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPGENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            9158..9346
                     /locus_tag="VV588_001630"
     CDS             9158..9346
                     /locus_tag="VV588_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU7083939.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            9407..10165
                     /locus_tag="VV588_001631"
     CDS             9407..10165
                     /locus_tag="VV588_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU7083940.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDVRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            10223..11077
                     /locus_tag="VV588_001632"
     CDS             10223..11077
                     /locus_tag="VV588_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU7083941.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEATYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            11189..12073
                     /locus_tag="VV588_001633"
     CDS             11189..12073
                     /locus_tag="VV588_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU7083942.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            12236..13009
                     /locus_tag="VV588_001634"
     CDS             12236..13009
                     /locus_tag="VV588_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEU7083943.1"
                     /translation="MELSAIYHGPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDGVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQ"
     gene            13076..13975
                     /locus_tag="VV588_001635"
     CDS             13076..13975
                     /locus_tag="VV588_001635"
                     /inference="COORDINATES: protein motif:HMM:NF012356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU7083944.1"
                     /translation="MTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYW
                     IEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAV
                     MNYPLSDSIKDYFLRGIKNTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTA
                     NEDVQLVKSALAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFM
                     KRLIKIRKYASVIISHGKYSLQEIKSDLVDLEWKYEGRILKAIFNQSTEDYLLEKEAV
                     VLASNCQELENQLVISPDGFVIF"
     gene            14250..14705
                     /locus_tag="VV588_001636"
     CDS             14250..14705
                     /locus_tag="VV588_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083945.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            15150..15626
                     /locus_tag="VV588_001637"
     CDS             15150..15626
                     /locus_tag="VV588_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7083946.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            15626..16402
                     /locus_tag="VV588_001638"
     CDS             15626..16402
                     /locus_tag="VV588_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU7083947.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQSIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQENGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYAINPNPARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAAEVLQEYLFGKWSKVEEEMLKVGEERMRDMSKSNGKDA"
     gene            16386..17195
                     /locus_tag="VV588_001639"
     CDS             16386..17195
                     /locus_tag="VV588_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
                     /protein_id="HEU7083948.1"
                     /translation="MEKMHSYIKYLTQEDPIITDEGKQIEILHLDIQDDPEIFEDWAK
                     QFRRNYCSDDELAEMIGFMNISPKEYLENFKLPSDSGIGLSTMSGDFGEILVSDYLQY
                     IEEYVVPRTRYDSKVNKNTSTQGSDVLGYKQDSSNVSNDEVVVIEVKSSASDSSSSKA
                     KNKLQEAINHSDKDFERFSTSIVASYLRLKKSNSDQANVVERFLNITDKPFNVIYGAV
                     AVYSNQSYDIDVIKTVVSKNHRDFQKLRLLVIHSNELMKFIRELYSKASEV"
     gene            17192..>17698
                     /locus_tag="VV588_001640"
     CDS             17192..>17698
                     /locus_tag="VV588_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence associated protein"
                     /protein_id="HEU7083949.1"
                     /translation="MIEFGRRSLYFSKLVRSKAKMIEFDIPLESHLPISEDAQKSFLG
                     ALAIVADTARKYFEVYINRKSFNLQLKNQLHNAAEYFDALLVSGLGNSAEYQDYIAIL
                     GTTAYYLCDYNGSSRVMINYISDDIQLLEDCMTLIKVFIDVVTDELFLNHTPIEGKYS
                     SELNTLVES"
BASE COUNT         6717 a         2420 c         3419 g         5142 t
ORIGIN      
        1 aaagaaaaaa tagaataaca ctattttcct cactattttt attaataata atcagtctat
       61 catttttcat tttacttatc ggagatgaaa gttattcttt ttcaactttg attaaagtct
      121 taaatagtga aactgttcct ggagctagtt tttcgattat ggaaattaga ttaccaaaat
      181 tattagcagg aattatagct ggctggtctt ttggattggc aggatttatc tttcaaacta
      241 tgttaagaaa tcctcttgca agtcctgata taatcggtgt cacaagttct tcatctattg
      301 cagcggtctt ttgcatattg gtattaaaaa caaatagttt aactactgga attatttcaa
      361 taacttgtgg actaacatca tctttaatat tatttttact agctaaaaaa gatggttttt
      421 cagcagcaag actgataata ttaggtattg gttttcaagc tgtcacaaga gcaggcacct
      481 catttttatt gttgaaagta gcaagatatg aattacaaga agttatgaga tggctcagtg
      541 gctctttatc ttttacaaag ttagatgaca tacctcttgt tctaatagta agtattattg
      601 ctactatatt agttttattt tttaataaaa gactagaaat tattgaactt ggtgaagaaa
      661 tagcaatcgg acttggagca aatcccgagc tttcaaggct tgttttaatt ttttgcgctg
      721 tatctttaac tgctttttct acttcaatta caggaccaat agcttgtata tcttttttag
      781 ctggtcccat agccttaaat attggcaaga aaagaagccc aatattagct ggattggttg
      841 gaattttact agttttgtta tcagacatat tctctcaaaa tattttacca gctagatatc
      901 cagtaggtgt tgtaactggc ttgttaggtt caccatactt aatatactta ctaataaaaa
      961 tgaacaggag gaatatataa tgaaaggtct gtggtcaaat aatcttacct gcggttatga
     1021 tgaaaaaata atcttggaaa atataaatat aaaaatacct gaagaaaaaa tatcagttat
     1081 tattgggtca aatggttgtg ggaaatcaac actcattaaa accttgtctc gacttataaa
     1141 gccattagag ggagaagtat tgcttgataa taaatcaatt aattcttata aagaaaaaga
     1201 tttagcaaaa cacatagcta tattacctca atctccaata atccctgaat caataacagt
     1261 agctgatctt gtaagccgtg gtcgtttccc ctacagaaag ccttttaaga gtcttggaaa
     1321 agatgacctt gaaataataa acagatcaat ggttaaggcc aatgttgaag atctagcaaa
     1381 taacctagtt gaagaacttt ctgggggtca aaggcaaaga gtatggatag ctctagccct
     1441 agcccaagat acaagtatcc tacttttaga tgagccaact acttacttgg atatctcata
     1501 tcaaatagaa ctattagacc tcttgactga tctaaaccaa aaatataaga caaccatttg
     1561 catgattttg cacgatataa atctaacagc aagatacgct gattacctat ttgcaattaa
     1621 agaaggtaaa cttgttgcag agggaaagcc tgaagatata ctaaatgata aactagttaa
     1681 agatatcttt aatcttgaag caaaaattat acgtgaccct atttccaatt cgcctctaat
     1741 gattcctatt ggcaagcacc atgttaactc ttaataattg aatattggaa ttcatttaaa
     1801 agtcgcaaat tttgaactga ccctcaaaag ttaggccaaa aaactaacta aaggaggtca
     1861 gttttttaat ggcaaataca gcacagaatt taagataaaa ttagtaaaag aatatcatga
     1921 atgaaaaata ggatatagag aataacagca atattaaaaa gatcaggact gataataaac
     1981 aaaaagaaag tacaacgact agttcaaaag ctaaaacttc aagtaaaaag ttattcaaga
     2041 aaatctagaa aatactcatc ctacaaagga caggtaggaa aaatatcaga caacaaaata
     2101 aaaagaaata tttattaccg aaaaaaaggg gaaatcgagt taagtaccaa caggctcatc
     2161 tattccaaaa agatatttac tcgatggaaa aactcctaga attagtgcta caaatattga
     2221 caatggtatc ttaggttact acgaagatat agatgataaa aattatagag tctttgaaaa
     2281 ttttatatct gtttcatttt taggagcagt cttttatcat aaatataaag caagcctaga
     2341 tatgaaaatt cattgtttaa aattaaaaaa taaagaattg aataaagaag tagcattcta
     2401 tttaacttca attattaggc aagctttaaa aaatactgaa tataaagatc aaatatctag
     2461 cacagtattg ccagatatca aaattaaatt accgatagac agtagaggta ctccagattg
     2521 gaattacatg gaaagatata tagaagactt aaaattaaaa tgcaatatag caaattataa
     2581 tatttaaaac aagaacgatt agaaataaaa atctagtcgt tttttatttt aagaaaggat
     2641 acatgatggc aagtaaaaga ttaagtattg aagaacagat tgaaaagaaa gaagaaagca
     2701 ttaagcaatt acaaaatcaa aaaagacagt tgaagaaaaa acttaatgaa caagaaagaa
     2761 aagcaagaaa caaaagactt atagaaaaag gtgcagtgtt tgaaagtatt tttgaagaaa
     2821 gtattgattt aacaaaagat gaattttata agttaataaa aacgttaaat gatgaagaaa
     2881 taagattaaa cataatggaa attttagaag aaagaataga tgataatgta gaaaaatcat
     2941 ctaaagatga aataacataa ttgtcccttg gttacaaggg cgcaattata caccctaaag
     3001 ggtgcttgcg tcctgcggag tcaaaccctt gcagggagca acaaccattc gctttttaaa
     3061 agtcaagggt aaataaactc gctaaggctc gcccttgact tttaaaattt gaaatgaaag
     3121 taacaattaa gccaacatac tgaaacaaca aaaattaatt cagtagtcgg cttttttaat
     3181 tctatcattt caaaacgctc attcacaaag aggatataaa aaaactatta agcctccacc
     3241 taaaacaaca aagaaaggaa gtgataaaaa tggcagacag ttttcatttt tcagtaaaca
     3301 taatatcaag aggaaaaggc aaaagtgcag tagcaagtgc agcatatata agtggagaaa
     3361 aaataaaaaa tgaatgggac ggagtaaccc atgactacac aagaaaagaa aaaatattag
     3421 taaaaaatat aatattgcct gatcatatac caaaagaatt taatgataag tctaccttat
     3481 ggaataaagt agaaatggca gaaaaaaatt ctaatgcaca actagcaaga caattcataa
     3541 taggactacc aaaagagtta tctttaagtg aaaataaaaa cctggttgaa agatatataa
     3601 aagaaaattt aacatcacaa ggaatgatag tagattatgc aattcatgat gagagtcaag
     3661 ataaaaatgg aaatatccat tgtcatataa tgaccataat gcgaccaata aacgaaaaag
     3721 gagagttctt agccaagtca aaaaaagaat atatcctaga tgaaaaagga gaaaaagtat
     3781 taaacaaaaa tggaaaacca aagacaagaa aagtagaact aacaacctgg aacgatacag
     3841 gcaatgtaga aaaatggaga gaaaattttt cagatctttg taacaaatat ttagaaagag
     3901 caggagcaga aaaaagagta gaccatagga gttttaaaag acaaaattca gattatctac
     3961 cgacaatcca tttaggatca gcagcaagtg caatggaaag aaagggaata gaaactgaca
     4021 agggaaacta taatagagaa ataagaaaat ataatcaact tgtaaaaaca ataaaagaag
     4081 agataaaaac attaaagggt tggataggaa atttattaga taacttatct actgcttatg
     4141 aaaaatttaa ggatatcgaa agagataagg taatagacaa ccctaaactt tttaatctaa
     4201 caaattatct attaacttat tcagaaattc aaaaagaaaa aagtaaatat ctaaaaggat
     4261 atgcaaaaac taataaagaa aaatatgact tcaaaaagct aacaagtgca tatagttatt
     4321 taagaaaaaa caacatagaa accataggtc agttacaaac aaaaatagaa actttaaagt
     4381 ctaatagtta taggctaaat aaaaaagaaa aagaaagtat ccaaaaacaa ataaagaaat
     4441 acaaagacct atccaaaaac aaagataaga caaaagaaaa aggaaagtaa aagaaaaagt
     4501 aaaaccaaac aaaaaagata tgaccagaga aatctaaagg gagtaacgaa aagttacacc
     4561 cttaaataac cataataaca agacttccga aaaacagaag tccagaattc cgaaaatcgg
     4621 aaatcaagaa tttcgattat cgaaaatcaa gaaaggagca gatatggcaa caaacaaaag
     4681 atactattgg ataaaattaa aagaagaatt tttcacagac aaaaggataa aaaggttaag
     4741 gagaatatct ggaggagata cctatacgat aatctaccta aaacttctac tactaagcct
     4801 aaaagatgag ggcaaactct attatgacgg agtagaaagt gattttataa aagagttagc
     4861 actaaccata gatgaaacag acgatgatgt aatggtaaca gtaaattatt taatcaatca
     4921 aggcttatta gaagttgtaa cagaaaatga tgaatactac ctaactgaaa taccaaactt
     4981 aatcggatca gaaacagcct gggcagagaa aaaaagaaga tacagacaaa ataaacagag
     5041 gacattgtcc ttaatgagtc caacccatgt ccgacaagag atagagaaag atatagagat
     5101 agataaagag agagagggag agatagataa aaagtccacc cccatttttt atggagaatt
     5161 caaaaatgta aggttaagca aagaagaata taaaaatcta aaagaaaaat taaactcaca
     5221 cacagatata atgataaata aactatccag atacatggaa agcagtggta agacctatca
     5281 aaaccactat gtgacaatat taaaatggta tgaagaagat aaagacaaac taagacagaa
     5341 aggtttaaat aaaaaaatga attatgatgt aggagaatct ttatagataa aaagaggtgg
     5401 aaaggcacta ttaaagactt taagtctaaa aaggtatcaa agtatgccag agataaaaaa
     5461 atataaatat gacactttaa aggcgattag aaaattaaag aaatgctaga agacttttag
     5521 atgacagtta ccaagagggt ctaattttca ctgctactta tgcagtggga attgaacctt
     5581 tttatataag caaattctat ttcaaaattg gttaccaaga aagacttctt ttcactgtta
     5641 agtataagag ggtaatttat agaattttgt tacatcaaga taaatatttt ctgatggtca
     5701 aattttaaaa agattaataa ctctcgataa attttgaacc ttaacaattg aatagaccaa
     5761 gacaagacgt taattatttt tggagcgtaa taacctatcc gtcaagatct ttcggctgaa
     5821 taattcggca aaaaaagttc tgctaagcaa aaagaaagtg agcgataagt aagagtttga
     5881 atatagggag ggatacccta tccgctatga agaaaatgag gataatgata cttctaaggt
     5941 tgaagccggc tcatccggaa tagaggcgga ggtgagattc ctatgttgct aatccaaagc
     6001 acttgtcaat gtcaaaaaac ttaattaaac aaataattat tagatataaa actttagagg
     6061 aggtatatat tggacaatga ctggaatgga ttggctgatt taatagcaaa tctgattgca
     6121 aaatatgctg gtgctttaga tttagataat ctacccgatc caacgccagc aaaaaatcaa
     6181 gatatgaaaa atagttttga catggcaaaa acacaaattg agacggacta ataaaagtgt
     6241 tataatatac ttgaaatgat agtccaaact taaattaaaa aaattatata tgatatagaa
     6301 aaattatatt gaggttaata ctatgtcaaa agaaaaaata aaagtatacc tctatacacg
     6361 agtatctacg tcaatacaga tagaggggta ttcgttagag gcacaaaaat cacgaatgaa
     6421 agcttttgct atttacaacg attatgaaat tgttggagag tatgaagatg ccgggaagtc
     6481 tgacaagtct attgaaggta gaatacagtt caatcgaatg atggaagata taaaatctgg
     6541 aaaagatgga gtatcttttg ttcttgtgtt taagttatca agatttgcaa gaaatgccgc
     6601 tgatgttctt tctacacttc agataatgca ggattatgga gttaatctta tctgcgttga
     6661 agatggcatt gattcatcta aagatgctgg gaaactaatg atttctgttt tatcagctgt
     6721 ggctgaaata gaaagagaaa acatccgtat tcaaacaatg gaaggtcgca ttcaaaaagc
     6781 aagggaagga aaatggaatg gtggctttgc tccgtatgga tataaacttg aagacggcaa
     6841 gctgtttata aatgaggaag aggcagttgc aataagaacg attttcgacc agtatgtaaa
     6901 tactacgata ggagccaatg ggatatctaa atacttagag aatcatggaa ttagaaaaat
     6961 cccaagacag aatggtaaga atcctttgtt tgatgcaggt cttataagaa agatattaaa
     7021 gaatcctgta tataatggga aaatagcatt tggaagaaga actttagaaa aagttcatgg
     7081 tacaagaaat gaatataagc aggttgaaca agatgaatat ctaatatctg aagggataca
     7141 tgaagctata gtttccgatg aagtttggca agctgctcag gttaagctaa aatctcaagc
     7201 aaagaaatat gagcatgtga ataaaggaaa agatacacgc acacacttgc tttctggaat
     7261 tgtaaaatgc ccgatatgtg gagtgggaat gtttgggaac aagtgtatca agaaaaagaa
     7321 agatggcaca aagtataaag atttttatta ctatggttgt aaacataggc agatgataag
     7381 aggtcataag tgtacattca gtaagcaaat tatagaagaa ttgttagatg atgctgttgc
     7441 agaggtgatt gtcaagatag taagtaatcc gaaatttgct tctatgatgc aagaaaaaat
     7501 caacatgaag gtggatacct ctgaaataga aaaagaaata gataattacc aaaaggaatt
     7561 gagaaagagt cattctacaa agtttaagct aattgaggaa atagataatt tagatgttga
     7621 agataagcat tataagagaa ggaaacagga tttagatgat agactatatc gtatgtatga
     7681 caaaatagat gaattagaat catcactaat tgatgcgaaa gcaaagaaac agactattga
     7741 agctgaaaag cttacaggag ataacatata taaggttctg atctattttg ataagctcta
     7801 taaagtcatg aatgatgtag agcgtaggca gttaatttca gctttgattt ctgaaattca
     7861 agtttataaa gaaaaacaat ctaacggaca atggctaaaa tccattactt ttaagctacc
     7921 aattatagaa gaaaatctca acataggttt ggacaatgat gaacaagttg aatgtgtaag
     7981 tttattagag aaacgtagtt aatcctcaaa aggttccccg aaccttttga gtcccactga
     8041 cgcatcacgc tgaggcggta tcactgcttg tacgagttga agcatcagca aagtaaaagt
     8101 agatgttcag ccaatgcgac gaggtgagac cgaaggtcga taaggtgtgt tctgggtata
     8161 ggactcgtaa agtaagtagg aaatatgatg agatgataca gagagcctga attggtcagg
     8221 tgacgtgctt atttacatta gcctgataat gaaaatggag agattatcga tggttatatt
     8281 ggaattgtac caaaatgatt attctaaaga tttagtagca tttgattcca tagaagatgg
     8341 gaaagccttt gtagctcaaa tcccgggata cactctggaa acagaagatg gttttgaagt
     8401 ggagtatttt aatcctaaaa acataccgga ttatatggaa attattttta acggaaatat
     8461 tgttccttta tctaaattta tgttcgatcc tggggaaaat gtaaacatta tttggaaaga
     8521 gatttcaaat ttatccctca aaaatgatag agtgatcgaa ggatattcaa aaattgatgc
     8581 atatgtcgtt aacaaccatg aagttaaagc ctatgtcgaa acaagagaaa cgaactatcg
     8641 taaagcaaaa gacttcttag aaagccgcgg atatgaaatc gacagaagct ttttcggaag
     8701 tgaagacggt gaagcgattc tttacagaaa aaaagggatc gaagtttggc atttcttgtg
     8761 tcacttagac ccaatgtttg tagagattga agatgtagaa ggatatgtta aagaagaagt
     8821 tggagagatt caatagtcaa ccaaagttcc ttgtgagtat atacctttgc tagtaaaaga
     8881 gtcaaaacgt tataacgaag ggggggaaga aaatccttga gtgtaagtct ttttcttgtt
     8941 tagagggaaa gtattagagt agccgctcat aatttatact agatttgata actgatttga
     9001 gacagatttt atttctataa atattgtgaa aattttttaa taccaaagat ttaaagttac
     9061 tgtgtaaaaa atcctctcca cttttaaact aatgtattat aaaagccagt tgacacaagt
     9121 gttacacctg tgatagaatt aacttgaggt gatgaaaatg gcaaccgata aaaatagaat
     9181 aatgattagt ttggatgata aaaatctaga gaaacttgaa aatttagtag aagatgctag
     9241 agatagaagg ggaatgcgac taacaaagtc ccaggttatt gaattactcc taaataccgt
     9301 tgattatttc gatgatatta tgggggctat ttactcaaaa aaataagagc aaaattgcta
     9361 ttatttttac aaattggtgt aacactagtg atataggagt gatgaaatgg ttgtttatat
     9421 tagacaaagt aaattaccaa gtgaggtttc aattaataaa tacaatgctc aagtaggtgc
     9481 ctacttacaa ggagaagaag ttattttata tcaatctttt tctgaaataa aagagttaac
     9541 aagtgaagat atagttgtag attatataat ggagactaga gcattactaa aaatgatggg
     9601 cttaaacgtt ccggtttatg actatcctat tgagcttaaa gagttttatg gtcgaaagat
     9661 ttatgctggt attttaggag agattgtgaa tatacctgat aattggggaa aatttattaa
     9721 gcctaaagct ggttcaaaag tctttactgg aagagttgtt aatggaaccc atgatttaat
     9781 aggtattggt ctacctttcg actatcctat atggattagt gaggttgtag aattcatagc
     9841 tgaatggcgt tgttttgtgt tagatgttcg cgtattagat gttcgaccct atacaggtga
     9901 ttatcatgca caatttgatg caagtgtaat tgatgaagcg atatcatgtt ggaaagatgc
     9961 gccaatagct tatggactag atatcggtgt tactcgcgat ggcagaacac ttgttgttga
    10021 agtaaatgat ggttatgcat tgggaaatta tggcctatct cctttaaaat caatcaattt
    10081 tcatagagct aggtggaaag aaatggtaaa accctatttt gaaaaaaatg aaatttttaa
    10141 aatccaacag gatgttattt tctaaaataa atatggtaga taaccaatat aaaaagcatc
    10201 aaaatgaaca aggaggaatc tgatgcttgg agcaattatt ggagatattg tcggttctgt
    10261 ttacgaatgg aacaatatca aaacaaagga ctttccttta tttcggaagg actgcttttt
    10321 tacagatgac acggttatga cctgtgctgt tgcagaagca attatgaatg gtggacaaaa
    10381 agacgatttc attgacgcga tgaagaaata tggcagaatg tatccgaatg ctgattacgg
    10441 tgctcggttt aatgcatggc taaacagcga taaccgtgaa ccttataata gctttgggaa
    10501 tggatcagct atgcgtattt ctccatgtgc ttggatcatg gactgtggtt tttatgcgaa
    10561 aactggtatg tggccatcat ctagaggact tacgagtctt tctgcagagg taactcataa
    10621 tcatccagaa ggtgtcaaag gcgctatggc tacagctgat gctatctttc tatgtcgttt
    10681 ttactttggt ggttattgta gagagtacga gcaatcaatt aacgacaatc ctacagagtg
    10741 taaaagacga attaaggatt atatagaaaa agaatacgat tacaatctat ctcaaacttt
    10801 agatgaaatc cgtcctaact atcgttttaa cgaaacatgt caggaaactg tccctcaagc
    10861 cattatcgcc tttcttgaaa gtagagactt cgaagatgcg ataagaaatg ccatctcact
    10921 tggtggcgac agtgatactc tcgcagcaat cacttgtagc atagcagagg caacttacgg
    10981 tattcctgat tggatcaagg ataaggccta ttcttacttg gatgaaccct taaaggatgt
    11041 agttaggcga tgggaaaata gaataaaagc gtattaatct ccagtacgtc agatttctct
    11101 tttctgtatt ttcattgtat aataggatta catttacttg catacgacga aatgtaaaca
    11161 tttctgttta aaattaagga taaaatcaat gaaaaaagca atggtaatta tcaaccctac
    11221 ttctggtggc gagaaggctt tggattacaa agaaaagctg gagaataaag caaaagaata
    11281 ctttgaatat gttgaaacca aaattaccga aaaagcgctg gatgcaacac attttgctga
    11341 agaagcttct cgtgagcagt atgatgcagt ggttgtgttt ggtggagatg gaactgtcaa
    11401 tgaagtcatt tcaggtattg atgagagaga ctacattcct aagttaggga ttatcccagg
    11461 cggtacgggt aacctcatta caaaactttt ggaaatcaat caagacatcg atggcgcaat
    11521 tgacgaactg gattttgatt taaccaataa gattgatatc ggtaaagcaa atgacaacta
    11581 ttttggttat atctttagta tcggttctct gcctgaggcg attcacaatg ttgaaataga
    11641 ggacaaaaca aaattcggta ttttaaccta tgctgtaaat accatgaagt ctgtcatgac
    11701 agatcaggtc tttaacatta aggttgagac agaaaatgga aattatgttg gtgaagctag
    11761 ccatgttttg gtccttttga caaattactt cgctgataag aaaatctttg aagaaaacaa
    11821 ggacggctat gccaacattt tgattctgaa agatgcctct atattctcca aattatccgt
    11881 cattcctgat ttattaaaag gggatgttat cgcaaatgat aatatcgagt atatcaaagc
    11941 gcgtaatatt aaaatctctt cagatagtga attggagtca gatgttgacg gagataaatc
    12001 agataaccta cctgtagaaa tcaaagtcct agctcagcga gtagaagtat tttcaaaacc
    12061 gaaagaggat tagtatatag agaaagcctt ttttaaggct ttttgtatac tttaaaagat
    12121 agttccttta acaacggaca ttccttgcaa atagtttaca aaaatagtat actggattta
    12181 ttgagtttga aaacgtttgc gtaaaatttg aatgaatact ttaggagaca aattgatgga
    12241 attaagtgct atttaccatg ggcctgagtc ggagtatgcc tatctttata aggataagaa
    12301 actccatatt cgaattcgaa ctaagaaagg ggacattgaa agcatcaact tgcactatgg
    12361 ggaccctttt atctttatgg aggagtttta tcaggataca aaagaaatgg tcaagataac
    12421 ttctggtacc ttatttgacc attggcaggt tgaagtgtca gttgactttg cacgtatcca
    12481 gtatctcttt gagctcagag atacagaagg tcaaaatatt ttgtatggcg ataaagggtg
    12541 tgtggaaaat tctctagaaa atcttcatgc aattgggaat ggatttaagt tgccttatct
    12601 tcatgagatt gatgcctgca aggttcctga cggggtttca aatacggtat ggtatcagat
    12661 atttcctgaa agatttgcca atggcaatgc tctattaaac ccagaaggga ctttagactg
    12721 ggattcatct gtcacaccta agagtgatga tttctttggt ggtgatttac aggggattat
    12781 tgatcatatg gattacttgc aagacttggg tattactgga ctatatcttt gtcccatctt
    12841 tgaatctaca agcaatcaca agtacaatac gacagattac tttgaaattg accgtcattt
    12901 tggagacaag gagacctttc gggaactggt ggatcaagcg catcatcgtg gcatgaaagt
    12961 catgctggat gcggtattta atcatattgg ttcgcaatct cttcaatgaa aaaatgtcgt
    13021 caaaaatggt gaacagtctg cttataagga ttggttccat attcaacaat tcccagtgac
    13081 aactgaaaag ctagttaata agagagactt accctatcat gtttttggtt tcgaggacta
    13141 tatgcctaag ctaaatacag ccaatccaga ggtcaagaat tatcttttaa aggttgcgac
    13201 ttattggatt gaagagttta atatcgatgc ttggcgtttg gatgtggcta atgagattga
    13261 ccatcagttc tggaaggatt ttcgtaaggc agttttagct aaaaatcctg atctttatat
    13321 cctaggagaa gtctggcata catctcagcc ttggctaaat ggagatgagt tccatgccgt
    13381 catgaattat cctttatctg atagtatcaa ggactatttc ttacgaggaa ttaagaatac
    13441 agaccagttc atcgatgaaa tcaatggaga gtctatgtat tacaagcagc agatttcaga
    13501 ggtcatgttt aatctcttgg attcacatga tacagagcga atcctgtgga cggccaatga
    13561 agatgttcaa ctggttaaat cagccttagc ctttctcttt ttacaaaaag gaacaccgtg
    13621 catttattac ggaaccgagc tagccttgac tggaggacca gatccagatt gtcgtcgttg
    13681 tatgccttgg gaacgtgtat caagtgacaa tgatatgctg aactttatga agaggctgat
    13741 taagattcgg aaatacgcgt cagtaatcat ttcgcatggc aagtatagcc ttcaagaaat
    13801 caaatctgat ctagtagatc tggaatggaa atacgaagga cggatcctca aagcaatatt
    13861 caaccaatca acagaagatt atcttttaga gaaagaagca gtagtactag caagcaattg
    13921 ccaagaattg gagaatcagc ttgtcatctc tccagatgga tttgtgattt tctaaaaact
    13981 agttgatgaa gattatggta catttcatat cttatatagt ataataaggc tagttactaa
    14041 acttgtaaag gagaacttaa atgaattgta gaggacatga aacaagacaa agaattgtta
    14101 gagattttga agtttagcct aaagcacata ttaagctgtt agcaaatcaa caaaaacata
    14161 gtgatgcagg agcaactatt gaagatgaat attatgtatt tatcgctgag agtaaaattg
    14221 atggcaagaa ggaagttatt cagtgttgca tgggtgcggc aagggatttt ttagaactaa
    14281 ttaatcacaa agggctacct ctttttaatc cgcttgtagg tgattctcat gtaaataata
    14341 gacaagaata tgacaataca gggagtggaa atttacaacc tgaaaagtgg aatgaaactg
    14401 caaagcagct ttataatgtt ataatgtggt tgattatttt atggaatgct aagccggata
    14461 cacctttatt taattttaaa gacgaagtaa ttaagtataa aacatatgag ccttttgaaa
    14521 gcagtataaa aagagtaaat actactataa agaatggtag taaagggaaa actctgactg
    14581 agatgattaa tggctacaga gcggataacg atattagaga tgaaatttgt aactttaata
    14641 ttctgaaaaa taaaattcgt gatatgaaag accaacaagg aaatacaatg gaatcttact
    14701 tttagttatt gttgaatttt gggtattcta taaaatatcc taattgagat ttaaatagta
    14761 gactatacaa tatagttaaa atatcagtaa aaacaacact ttattgaggt attggatacg
    14821 ctttgctaat agcctaataa tcacatgtgg agtgttgcta caacgaaaaa ggtgataatc
    14881 cttgatttca agctatttta taagcatttt gtctttgtag ataaaggcaa ttttgacaat
    14941 aaaaatccta aaaggtgaat cgttatagat gtatttgtag atatcgtttg cgcatcgaaa
    15001 aaattaatac aagaataaat atttatggct ctttaggtga cttttataga agtaaagttt
    15061 aggatagaaa aacagtcaat aacgcaccat ttttggtgcg ttatgctttt ttatgctata
    15121 atggatttat aaaaataaag gagtttgcca tgattggaaa aaacataaaa tccttacgta
    15181 aaacacatga cttaacacaa cacgaatttg cacgaattat aggaatttct cgaaatagct
    15241 tgagtcgtta tgaaaatgga actagttcag tctctacgga attaattgac atcatttgtc
    15301 agaagtttaa tgtatcttat gtcgatattg taggagaaga taaaatgctc aatcctgttg
    15361 aagattatga attgactttg aaaattgaaa ttgtgaaaga aagaggtgct aatctattat
    15421 ctcgactcta tcgttatcaa gatagtcagg gaattagcat tgatgatgaa tctaatcctt
    15481 ggattttaat gagtgatgat ctatctgact tgattcagac aaatatctat ttagtagaaa
    15541 attttgatga aatagagaga tatagcggct atttggatgg aattgaacgt atgttagaga
    15601 tatctgaaaa gcggatggta gcttaatgga aatccaagat tatactgata gtgaattcaa
    15661 acatgcttta gcaaggaatc ttcgttcact gacaagagga aaaaagtcca gtaaacaatc
    15721 tatagcgatt ttgcttggag gtcaaagtgg tgccggtaag actacaattc atcgtattaa
    15781 acagaaagaa tttcaaggaa atattgttat catagatggt gatagttttc gttctcagca
    15841 tccacactat ttagaactgc agcaagaaaa tggcaaagat agcgttgaat acaccaaaga
    15901 ttttgcaggg aaaatggtag agtctttagt aaccgaattg agtcatttgg gatacaatct
    15961 tttgatagag ggaactttac gaactattga tgttccaaag aaaacagcac aactattaaa
    16021 aaataagggg tatgaggtac aattagcctt aattgcaacc aagcccgaat tgtcctatct
    16081 gagcaccctt atccgatacg aagaactgta tgctatcaat ccaaatccag cacgcgcaac
    16141 tccaaaagaa catcatgatt tcattgtaaa tcatctagtt gataatacac gacaattgga
    16201 agaactagct atttttgaaa gaattcaaat ttaccaacga gatagaagtt gtgtatatga
    16261 ttcaaaagaa aatacaactt cagcagcaga agtgctacaa gaatacctct tcggaaaatg
    16321 gagcaaggta gaggaagaga tgttgaaggt gggagaagaa cggatgaggg atatgagtaa
    16381 aagtaatgga aaagatgcat agttatataa agtatctaac tcaagaagat cctattatta
    16441 ctgatgaagg taagcagatt gagattcttc acttagatat tcaagatgac ccagaaattt
    16501 ttgaagattg ggcaaaacaa ttcagaagaa attattgttc tgatgatgaa cttgctgaaa
    16561 tgataggttt tatgaatatc tcccctaaag agtatcttga aaattttaaa ttaccctcgg
    16621 atagtggtat tggcctttca acgatgtcag gagattttgg agaaatatta gtatctgatt
    16681 atcttcagta tattgaagaa tatgtggttc ctaggactcg ttatgatagt aaagtcaata
    16741 aaaatacttc aactcaagga agtgatgttc taggatataa gcaagattct tcgaatgtgt
    16801 cgaatgatga ggttgtagtt attgaagtaa aatcatctgc atcagattct agtagctcta
    16861 aagcgaaaaa taagcttcaa gaagctatta atcattctga taaagatttt gaacgatttt
    16921 caacctcaat tgtagccagc tatttgaggt taaagaaatc taatagtgat caagcaaatg
    16981 tagtagaaag atttttaaac ataacggata aaccgtttaa tgtaatctat ggagctgttg
    17041 cagtctactc caatcaatca tatgatattg atgttatcaa gacagtagtt tcaaaaaatc
    17101 acagagattt tcagaaatta cgactattgg tcattcattc taatgaatta atgaaattta
    17161 ttagagaact ctattcgaaa gcgagtgagg tatgatagaa tttgggagaa ggtcattata
    17221 tttttcaaaa ttagtgcgtt caaaggcaaa gatgattgaa tttgatattc ctttagaaag
    17281 tcatttacca atttcagagg atgctcaaaa atcgtttctt ggggcactag caattgttgc
    17341 agatactgct aggaagtatt ttgaagttta tatcaatcgt aagagtttta atttacaatt
    17401 aaaaaatcaa ttacacaatg ctgctgaata ttttgatgca ttgctggtgt caggattagg
    17461 aaattcagct gaatatcaag actatattgc aatattgggt accacagctt attatctatg
    17521 cgattataat ggtagttcga gagttatgat taactatata tcggatgata tccagttatt
    17581 agaagactgt atgactctta taaaagtatt tattgacgtt gtaacggatg aactcttttt
    17641 gaatcatacg ccaatagaag gtaaatactc tagtgagtta aatactctag ttgaatca
//
LOCUS       DAVIME010000045        17622 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVIME010000045 DAVIME010000000
VERSION     DAVIME010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.045"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..64
                     /locus_tag="VV588_001641"
     CDS             <1..64
                     /locus_tag="VV588_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU7083950.1"
                     /translation="TSMLSHLKKEVEIYYQAKER"
     gene            complement(116..703)
                     /locus_tag="VV588_001642"
     CDS             complement(116..703)
                     /locus_tag="VV588_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU7083951.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQKLVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            945..1616
                     /gene="sdaAB"
                     /locus_tag="VV588_001643"
     CDS             945..1616
                     /gene="sdaAB"
                     /locus_tag="VV588_001643"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU7083952.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            1625..2497
                     /gene="sdaAA"
                     /locus_tag="VV588_001644"
     CDS             1625..2497
                     /gene="sdaAA"
                     /locus_tag="VV588_001644"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU7083953.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            2519..3151
                     /locus_tag="VV588_001645"
     CDS             2519..3151
                     /locus_tag="VV588_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU7083954.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            3201..3458
                     /locus_tag="VV588_001646"
     CDS             3201..3458
                     /locus_tag="VV588_001646"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083955.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKIVDGTDEVSSKHCFKVVDGTDEVS
                     SKHCFEVADRTDEVSSKHCFKVVDGTDEVSNHIRQGDVDVI"
     gene            complement(3544..5394)
                     /locus_tag="VV588_001647"
     CDS             complement(3544..5394)
                     /locus_tag="VV588_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU7083956.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(5436..6593)
                     /locus_tag="VV588_001648"
     CDS             complement(5436..6593)
                     /locus_tag="VV588_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU7083957.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVINNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            6651..7817
                     /locus_tag="VV588_001649"
     CDS             6651..7817
                     /locus_tag="VV588_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU7083958.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            7956..8282
                     /locus_tag="VV588_001650"
     CDS             7956..8282
                     /locus_tag="VV588_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU7083959.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            8269..8862
                     /locus_tag="VV588_001651"
     CDS             8269..8862
                     /locus_tag="VV588_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU7083960.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            8855..9766
                     /locus_tag="VV588_001652"
     CDS             8855..9766
                     /locus_tag="VV588_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU7083961.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9829..10893
                     /locus_tag="VV588_001653"
     CDS             9829..10893
                     /locus_tag="VV588_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083962.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(10965..11825)
                     /locus_tag="VV588_001654"
     CDS             complement(10965..11825)
                     /locus_tag="VV588_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU7083963.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(11947..12933)
                     /locus_tag="VV588_001655"
     CDS             complement(11947..12933)
                     /locus_tag="VV588_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU7083964.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(13205..14680)
                     /locus_tag="VV588_001656"
     CDS             complement(13205..14680)
                     /locus_tag="VV588_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU7083965.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(14764..15687)
                     /locus_tag="VV588_001657"
     CDS             complement(14764..15687)
                     /locus_tag="VV588_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU7083966.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(15701..16630)
                     /locus_tag="VV588_001658"
     CDS             complement(15701..16630)
                     /locus_tag="VV588_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7083967.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(16949..17299)
                     /locus_tag="VV588_001659"
     CDS             complement(16949..17299)
                     /locus_tag="VV588_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083968.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         5239 a         3788 c         3319 g         5276 t
ORIGIN      
        1 aacttctatg ctgtctcatc tcaaaaaaga agtagagatc tattaccaag cgaaggaaag
       61 ataaaaaagc cgagggattt cctcgactct ttacatatta tttgttcgtt agttcttaat
      121 accagccatt gttaagccag aagtttttag cagctgtcca tgaaccgtaa cgtcctgcaa
      181 cgtaggcatc tgctacacgt tcttggtttt cagctgagta gtcaccgttc aggtatgaat
      241 ctgttaattg gtaacgtccg atataacgtc catttgtagc tgtatagcta ccacctgatt
      301 ctttttgagc gatccattct ttggcttctg cttcagatcc gcttacagtt gaaacaactg
      361 tttcacttac tactggagtt tctgccactg gagctgaaac agtttcatct tgagcggctg
      421 gtgccgcata agtagctggc gctggtgttg caacaggcgc tacagggcca tcgataacca
      481 acttttgatc aacataaatc aaatgaatgt tatcaatgtg gttgttttct gccaattttt
      541 caactgttgt gttgtgagtt tcagcgattt ctgaaagtgt atcaccttct ttaacagtgt
      601 aagttgatga ttcttgagca gatacaaatg atggagcaaa tactgcaaac aaggcagcta
      661 ctcctgcaag agttgcttta atctttttag ttattgattt catattcgaa aattctcctt
      721 ctttctatag ttctatcata ccctttaaat attaccgttt cttgacactt ttatgtagaa
      781 atattacaaa attatttttt atttccctaa ataaggtgtt ttttgtcata aaagatacta
      841 tttttatgct atttgaggta ttagaaaggt tttcatccac aattaaagcc aagcccctca
      901 ttctttgata taatagagat aagaattttt ataaggggaa actgatgaaa tcacttcgtt
      961 ttcaatctgt ctttgatatc atcggaccag ttatgattgg cccatctagt agccataccg
     1021 ctggtgctgt tcgtattggg aagattgtct cttccatttt tgatgatact ccgacagaag
     1081 ttgaattcca actttttaac tcatttgcca agacctatcg tggtcacgga acagacctag
     1141 cccttgttgc aggtatttta ggaatggata cagatgatcc tgaaattcca aatagtctgg
     1201 aaattgccca caagcgtggt atcaagattg tctggaccat tcagaaagac agcaatgccc
     1261 ctcaccctaa caccactaaa attactgtta aaaatgccca caagaccatc agcgtgactg
     1321 gtatttctat cggtggagga aatattcagg taaccgaact caatggtttt gccgtctctc
     1381 tcaatatgaa tacaccgact atcatcatcg ttcatcaaga tattccaggt atgattgccc
     1441 ttgttacaga ggcgctttcc cgctatggta tcaatatcgc ccagatgaat gtcactcgtg
     1501 aaaaagctgg tgaaaaagcc attatgatta tcgaagttga cagtcgcaac tgtgatgagg
     1561 ctatcgaaga aattcgaaaa atccctcatc tccacaatgt caatttcttt aaataggagg
     1621 aagcatgttt tattctatca aagaattggt cgagcaagca gatctggact ttcaaggaaa
     1681 tgtcgcagaa ctcatgatta caacagagtt tgaattgacc ggtcgcgaac gtgaagaagt
     1741 cttccttctc atggaacgca atctggaagt tatgaaagcc tctgtccaac ttggcctcaa
     1801 tgaaaataaa tctcgtagtg gcctgacagg tggagatgct gccaaattgg atcactacat
     1861 cgaaaacgga aaaactctgt cagattatac gattctctcg gctgcccgaa atgccatcgc
     1921 agtcaatgaa cacaatgcca aaatgggctt ggtctgtgcc actccaaccg ctggaagtgc
     1981 tggctgtctg ccatccgttc tcactgctgc tattgaaaaa ttagacctca gccacgagca
     2041 acaattggat ttcctctttg ctgctggtgc ctttggacta gtcatcgcaa acaatgcctc
     2101 catctcaggt gctgagggtg ggtgtcaagc tgaagttggt tcagcctctg ctatgagtgc
     2161 tgccgccttg actctggctg caggtggaac accttatcag gccagtcaag ctattgcctt
     2221 tgtcattaaa aatatgctag gcctcatctg tgaccctgtt gcaggtttgg tcgaagttcc
     2281 ctgtgtcaaa cgtaatgcca tgggagctag ctttgctttc atcgcagcag acatggcctt
     2341 ggcaggtatc gaatctaaaa tccctgtgga tgaagtgatc gatgccatgt accaagtagg
     2401 agcaagcatg ccaactgcct ttcgtgaaac agctgaaggt ggactcgcta ccacccctac
     2461 tggtcgtcgc ctccaaaaag agattttcgg agaataagct tatcaaatag gagaaaccat
     2521 gacctctatc acagcgattt ttttcgattt ggatggaacc ctcgttgata gttctatcgg
     2581 gattcacaat gcctttacct atacctttaa agagctgggg gtgcctagcc ctgatgccaa
     2641 aactattcgt ggttttatgg gaccacctct cgaaagtagt tttgcgacct gcctgtccaa
     2701 agaccaaatt tctgaagcca tgcagatata tcgttcttac tataaggcaa aaggcatcta
     2761 tgaagctcaa ctctttcctc agattataga cttgcttgag gagttatcga gcagttatcc
     2821 actctacatc accacgacaa agaatacatc tactgctcaa gacatggcca aaaacttgga
     2881 aatccatcat ttctttgatg gtatttatgg ttctagccct gaagcacccc ataaggcaga
     2941 tgtcattcac caagccttac agacacatca actagcacca gaacaagcca tcatcatcgg
     3001 agataccaag tttgatatgc tgggagctcg agaaacaggt attcagaaat tggccgtcac
     3061 ttggggattt ggagagcaag cagatctact aaactatcaa cctgattata tcgctcacaa
     3121 acccttagaa gttttggcgt attttcaata gcatagactg ggtaacaact ccatttcaga
     3181 agaaaatgaa gtaatactca atgaaaatca aagagcaaac taggaaacta gctgcgggct
     3241 gctcaaaaca ctgttttaag attgtagatg gaactgacga agtcagctca aaacactgtt
     3301 ttaaggttgt ggatggaact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
     3361 gaactgacga agtcagctca aaacactgtt ttaaggttgt agatggaact gacgaagtca
     3421 gtaaccatat acggcaaggc gacgttgacg tgatttgaag agattttcga agagtataag
     3481 tctctacata ataaaacgca tattaccaag gttgtttaac ttgataatat gcgtttttct
     3541 tttttattca atgtgggttg tttgattagc aaaggcgata atagcttgct tcaactcatc
     3601 tccactgaga gtgcggaact ctccaatctt ttgattgatg gattctaaag gcatgacatt
     3661 aaccttacca acgaaaatct tatccataac ttgattgtca acgagttcgg ttgataccaa
     3721 gagttcttcg tagagttttt cacctgggcg gattccaact tcaacgattg gaatttcact
     3781 ctcagtgtgg ccacttagaa gcaccatctt cttggccaag tcataaatct tgactggttt
     3841 gcccatatca aggataaaga cttccccatc tttggcataa gcaccagcat ggataaccag
     3901 acgactagct tctggaatgg tcataaagta acgggtcatg cggaagtctg tcaccgttac
     3961 aggcccacct tcagcaatct gacgttcaaa gactggaatg acactaccac ggctaccaag
     4021 aacattccca aaacgaactg cacagtaggt tgattggcta cgttggttaa agccagtgac
     4081 aatcaactcc gccacgcgct tggttgctcc cataacattt ggtggattaa ctgccttatc
     4141 tgtcgaaatc ataaccatct taggcacctt ggcttcatca acggctctag caacattgta
     4201 agttccacgg atattgtttt tgaaggcttc ttttggattg cgctccatca taggaacatg
     4261 cttgtgggct gccgcatgat aaacaatagc aggtttgtac tgctcaaaga cttgcaacaa
     4321 acgatcatag tcttgaatgt ccgcaatcac aggtacataa tcaatccctt ggaacttacg
     4381 aatcaattca tgataaacaa ggtagattga gttttcccca tgaccgagca agacaatgcg
     4441 ttcaggattg aagcgactaa cttgacgaca gatttcagaa ccgattgaac ctccagctcc
     4501 tgtgactaag atggtcttac ctgtcagttc tgcacccaga cgcgattcgt caagacggat
     4561 ttcctgacga cccaaaaggt ccgtaatatc aattttttgg aagccagtac ctgcttggtg
     4621 aaggccctga acaacagttt caaccttagg catcttgtaa catttgacac ccagcttatt
     4681 acacatctgc aagatacgct catattctga cggatccagc gacggaatcg caacgatgac
     4741 acgctcgatt tgatggcgtt tggctaattc aggcagattg tcataagagc ccaaaacagg
     4801 aataccacca agtttttgac cctttttctt agaatcctta tccaaaatac cgaccagttc
     4861 taattcactg gttggatgtt ggtaactatc cataaagaga gccccaccat caccggcacc
     4921 aatcaagaag gtccgacggt gttctccatc accactacct tttttgcgtc tggagtagat
     4981 taactgccaa gtaatccgtg gcaataaaat caagaaggta ctcaacaaga taaagagaat
     5041 gatgaaacgg atggagaaga gtggcaagaa ggcataacag atactatatg acaagacact
     5101 gctagcagtc acaccaaaaa agattttcat gaaatccgta atcttgctgt aacgactaat
     5161 gctcgcgttc aacccccaaa aaccaatcat caattgatag aacaagaagg ccaaactcgt
     5221 atagataatg tagtcaacag gtgctggatt aatcagccca taaaataaaa tataagatac
     5281 aattatggaa accaccatac tgaaaatatc aaatattccc cagaaaacct gcttttgttg
     5341 tttatttaaa atttccacca gatcaatcac ataatctgtt agttttttat tcatagaaat
     5401 ctactcctcc ttaaaagagt tttactatat tgttattata gcatattttg atttatttgg
     5461 cttattttat ccaaataaat tattgttccc ttgtactcct tcttccattt aaatcctcta
     5521 attaaaccta caatcgtccc aaggccataa gcaaagtgaa tggaaaataa aagaaagggc
     5581 atcacaatta gaaatccatt tttatgtttt aataaagtca gcaaagtgag taatgacaaa
     5641 agtagaaaat aggcacctaa tagtaaagtt atgaatacga atgtgatcgg taacaatgct
     5701 agactaaaca caagactcaa aacaaataaa caaggaacat agtgaaataa tgataaacac
     5761 ttaaactgaa catgacttgt caagccaatc cacaaaccat ttgaatactt ttgatgcagc
     5821 attttcttga atgttggtcg aatatactga taagatagaa tacttgggct atagcggatt
     5881 ttataaccat gttctcgaat tctataatga atatcattat cttcagttcg gccaagttgc
     5941 tcatttacta aaccaacctt ctggaaaacc tctcgtttat acatcccatg aaaaatagaa
     6001 gaaacatatc tatcctcgga actatttcga taattggcaa tgctactgcc aaacatattt
     6061 tcctcaacaa gatgcaaggt ctctgcccat tttccttttc cttcgacaat cgtcggtcta
     6121 ggccccccac agacaaattc accttgttga ataatagcca cattgttaat tacaaaactc
     6181 tcagtaactt ttgaatgagc atcaattttt aaaataaggt cccctacaga atgtttaact
     6241 cccaggttaa aaccactagc ttgatttttc ttaggattgt tatacaatct aattgagtta
     6301 aactctgtat cttcctttat aaattgctga atgatagctg tggtcccatc tgtggacata
     6361 gcatttataa atagaatttc aatatcctct ttaggatagg tttgattttt taagtcttca
     6421 attagaccag gcagatattt ttcttcattg tatgcactga ttacaatgga tacgagaaga
     6481 ctttcaacat tttgagtcac tactactctc ctgaattttt ccttccacca ttctatcata
     6541 attttcaaga ctttcccatt tttatcttga aagccagaaa ccttacttga cattatagtg
     6601 aaaaagcctt aaaataagct gttattaaaa tcagctagaa gaggtattat atgaaaaagc
     6661 aatcactctt ttttgttcca ggtattatcc tgattggtgt ttccttgcga actcctttta
     6721 ctgttttacc cattattttg ggaaatattt cgcaaggtct ggaggtagaa gttagttcgc
     6781 ttggtgtctt gaccagcctg cctctcctta tgtttaccct cttttcacca ttttctaccc
     6841 aactggctca gaaaatcggc ttggagcatc tcttcaccta cagcctcttc ttcttgacca
     6901 tcggctcact tattcgacta atcaatctgc ccctgctcta tctaggaacc ttgatggttg
     6961 gggcaagtgt cgcagtcatc aatgtcctgc ttcctagtct tatccaagcc aatcaaccaa
     7021 agaaaattgg ttttctgacc accttatatg taacgtctat ggggattgca acggctctgg
     7081 cttcctatct agctgtgccc attacacaag ccagttcttg gaaaggactt atccttctcc
     7141 tcacgttact ctgtctagca acttttttgg tctggctccc aaatcaccgc tataatcata
     7201 gactagctcc acaaaccaaa caaaaaagtc aaataaaggt catgcgtaat aaacaggttt
     7261 gggcaattat tatcttttca ggttttcaat ccttgatctt ttacaccgtc atgacctggt
     7321 tacctaccat gtctatccat gcaggtctat ccagtcacga agctggcttg ctgacttcta
     7381 tcttatctct gattagcatt cctttttcaa tgaccatccc aagcctgaca accagtttat
     7441 ctactcgcaa ccgtcagctc atgctcactc tggtttcact agctggtgtg gtcggcattt
     7501 ccatgctctt tttcccaatc aataatttca tttactggct tgccatccat ctcctcatcg
     7561 gaaccgcaac cagtgccctc ttcccttatc tcatggtcaa cttttcactc aagacaagcg
     7621 cccctgaaaa gacagcccaa ttgtccggcc tatctcaaac aggaggctat atcctagcag
     7681 cctttgggcc aaccctcttt ggttacagtt ttgacctgtt ccactcttgg gtaccatctg
     7741 tagctgccct cttgctcatc gatatcctga tgactgtggc cctctttaca gtggacagag
     7801 cggataagat cctttaaact tctagtttta gctagaagtt ttttatatat aaaaatttta
     7861 cacatttctc ttgacagggc tttcttttag atgtacaatg tatgtgtaga aaaattatat
     7921 ataaaaatct tacacattag aaaaggaggt ttcccatgta ctttccaaca tcctctgcct
     7981 tgattgaatt tctcatcttg gctgtactgg agcagggtga ttcttatggt tatgagatta
     8041 gccaaaccat taagctgatc gctaatatca aagaatccac actctatccc attctcaaaa
     8101 aattggaagg caatagcttt ctgacaacct attctagaga gttccaaggt cgcatgcgca
     8161 aatactactc cttgacaaac ggtggtatag agcagctctt gaccctaaaa gatgaatggg
     8221 cactctatac agacaccatc aatggcatca tagaagggag tatccgccat gacaagaact
     8281 gaatacctga ctcagctaga actctatctc aagaaactac ctgaagctga ccgtatcgaa
     8341 gccatggact atttcagaga gctctttgac gatgctggag tcgaaggaga agaagaactc
     8401 atcgctagtt tgggaactcc caaagaagcg gcccacgaag ttctatccaa tcttctcgat
     8461 aaaaaaatca atgaagcacc cgctcaaaaa aataaccgac aaattttaca tatcgccttg
     8521 ttagccctcc ttgcagcacc tatcggcatt cctctgggaa tcgccatcct cgtgaccctg
     8581 ttcgcaattc ttgtagccgc tttgactgtc attctggctt tctttgcagt ttccatactg
     8641 ggtatcatcg gcggattcct atttttagtt gaaagtttca ctgtcctcgc ccaagccaaa
     8701 tcagccttta tcttgatttt tggttctggt ttactggcta tcggtgcttc ttcgctagtt
     8761 ttacttggca tttcctatgc aactcgcttc ttcggtctac tcattgttcg tctggtacaa
     8821 tttgttctta aaaaaggaaa gagaggtaat cagcatgcgt aaatggacaa aaggatttct
     8881 catctttggt gtggtgacta ccgttatcgg ctttatcctg ctttttgtag gtatccaatc
     8941 tgacgggatt aagagcctac tttccatgtc caaagaacct gtctatgata gccgtacgga
     9001 aaagctaacc tttggcaagg aagtcgaaaa cctagaaatt actctccacc aacacacgct
     9061 caccatcaca gactctttcg atgatcaaat ccacatttct taccatccat ctctttctgc
     9121 tcaccatgat cttatcacca atcagaacga tagaactctg agtctcactg ataagaaact
     9181 gtctgaaact ccgtttctct cttctggaat tggtgggatt cttcatatcg caagtagcta
     9241 ctctagtcgt tttgaagaag ttattctccg actaccaaaa gggagaactc taaaagggat
     9301 caacatctca gccaatcgcg gacaaaccac catcataaat gctagccttg aaaatgcgac
     9361 cctcaataca aacagctata tcctccgaat tgaaggaagt cgtatcaaaa acagtaaact
     9421 cacaacgccc aatatcgtta atatctttga tacagttctt acagatagtc agctagagtc
     9481 aacagagaat cacttccacg ctgaaaatat ccaagtccat ggcaaggttg aactgactgc
     9541 caaagattat ctcagaatca tcctagacca gaaagaaagc caacgaatta actgggacat
     9601 ctcaagcaac tatggttcta tcttccaatt cacaagagaa aagcctgaat caagaggtac
     9661 ggaattaagc aacccttaca aaactgaaaa aaccgatgtc aaggatcaac tcattgcgag
     9721 atctgatgat aatattgatc taatatccac accaagcaga cgttgacaaa aacgcttaca
     9781 tttgctacta tggaaacata tttatctaac taaaaaggag gttctaccat gaaacaagaa
     9841 tggtttgaaa gtaatgattt tgtaaaaaca acaagcaaga acaagcctga agagcaagct
     9901 caagaggttg cagacaaggc tgaagaaacg atagccaatc tcgatacacc aattggaaaa
     9961 aatactcaag tagaggagga agtctctcaa gctgaagtcg aactggaaag ccagcaagaa
    10021 gagaaaattg aaactcctga aggcggtgaa gcgagaacag aaatagaaga aaagaaggca
    10081 tctaattcta ctgaagaaga gccagacctt tctaaagaaa cagaaaaagt cactatagct
    10141 gaagagagcc aagaagctct tcctcagcaa aaagcaacca cgaaagagcc acttcttatc
    10201 agtaaatctt taaaaagtcc ttatatcccc gaccaagctc caaaatctag ggataaatgg
    10261 aaagagcaag tgcttgattt ttggtcttgg ctagtagaag cgatcaaatc tcctacaagt
    10321 aagttggaaa caagtatcac acacagttac acagcctttc tcttgctcat tctgttttct
    10381 gcatcttcct ttttctttag tatctatcac atcaaacatg cttactatgg acatatagca
    10441 agcattaaca gtcgcttccc tgagcagcta gctcctttaa ctcttttttc tatcatctct
    10501 atcctagtag cgacaacact cttcttcttt tcattcctct tgggtagttt cgttgtgaga
    10561 cgatttatcc accaggaaaa ggactggacg ctagacaagg ttctccaaca atatagtcaa
    10621 ctcttggcaa ttccaatctt cctcactgct attgctagtt tctttgcttt ctttgatagc
    10681 ctacgattta cagctctctt gtgtgtgatt agcattggaa tcattctgct tgccagtctc
    10741 catatcatta caagaccaag tcaagcaagt gaaaccgact ccttctatca attattcttg
    10801 tctgtccttg tgaacggagt tattatcctc ctcttctttg tagctgaagt ggcactgatt
    10861 ggagattatc ttcgtatctt ggcctttctt taaaattcaa tcctgtcatc cttggcagga
    10921 ttttttctat gtcaaaaaag caagtcgatt gacctgcttc tgctttactt ttcttgtgct
    10981 aatgttttaa aatctttgtc taatatgggt tgcacttcta tttgattggc gtctagttgg
    11041 tggtaaaaag atgggggtaa tacctctaag aattttgcat agtccaagcg agctatggat
    11101 tcatagtctt ctggtttaga gccgtctcct gtgatttgaa ccaagtcaat ctcccactgg
    11161 acttccttat ccaccaattg ctcaatatag gctgcaggaa caaacggttc tctcggtaaa
    11221 actgtcttga ctccttgagc taaatggtaa acgccatgca cttttccttc tccatcctga
    11281 tagaaggaaa ctcttgcaaa gtaggcatct gtctcttgaa ccgcacgcac acgcgcttca
    11341 aactgagcca agccatctgc ctctaaaaag cttttcaagt tctcacgact aaagaaaata
    11401 ggattaaaaa ttccttggca aatcgtaaaa cgagctacag ggtctgctag ataggcttga
    11461 atacttgctt ggaaataagc ttcaaaatca aaaccatcta gcccttcaat atcagtccct
    11521 gtataagcaa gcaaagcatc taaaaatgac ttgataatct gccagtctgt ctttgttagt
    11581 aggtcaggaa gatcgacacg gtaagccttt tgaccatcag cataactgac cttaaagaga
    11641 aattgtgatt gccccactat cgcacactca atatactcga gacgattaag aggctgacga
    11701 agatagacta catcatagct atgtgactcc aaaccgtcta gcaaggccaa gatcgacttg
    11761 gcattcaaaa tctcttgttc tcctaaaatg ctctgtttat ttggaataaa aaatgttttt
    11821 gccataactg gactcctttg aaatcgttta catacagtat accttatttt cctgaaagat
    11881 acaaaaacaa actttagatt tttgagtaca aagcatagaa aaacagcccc tgaggactgt
    11941 ttgatcttat acagtagctg cctgatccaa gctttcaccg atagcggcta ggcgctcaat
    12001 cacttcagct tgtgtcaatt cattttttga aacatagcgg ttacgtgggt gaacacggca
    12061 ctcgtgtgag catccacgaa ggtacttgtc ttcattttct tctgatgtca agatacgacg
    12121 gttacagaag ggatttccac agttgacata acgttcacat ggtgttccat caaaccagtc
    12181 tttccctacg atggttgggt tgacatggtt gacatcaacg gcaatacgct cgtcaaagac
    12241 gtacattttc ccatcccaaa gctcaccttg aacttctggg tctttaccgt aagttgcgat
    12301 tcctccgtgc aattggccga catctttgta gccttcacgg accatccagc ctgagaattt
    12361 ctcacagcga acgccacctg tacagtaaac cacgacacgc ttgtccatga atttttcctt
    12421 gttatcacgg acccattgtg gtaactcacg gaagttgcga atatctgggc gaatagcccc
    12481 acggaaatgt cctaggtcgt actcataatc gttacgtgtg tcaaggacaa cggtatcttt
    12541 atcaagaagc gcttctttga actcttttgg agacaagtaa gcacctgttg tttcaagtgg
    12601 gttgatgtca ttgtcaaagt cgttgtcttc caaaccaagg tggacaattt ctttcttgta
    12661 gcgaacaaac atcttcttga aggcttgttc attttcttcg tcaatcttga accagagttc
    12721 ttccattcct ggaaggctgt gaacgtagtc catgtatttt tgagttgttt catagtcacc
    12781 tgaaactgtt ccgttaattc cctcgtcagc gactaggata cggcctttaa ggccgattga
    12841 tttacagaaa gccaagtggt ctgcagcaaa ttgctctgca ttttcaattg gagtataaag
    12901 gtagtaaagt aagacacgaa tatcttttgc cataagattt gttctctttt ctattcttaa
    12961 attttctaaa ttttttattt atctacacta gtatacctgc ttgagaaaac gaatgcaatt
    13021 tatttgactg gaaattgtag agggttctcg aaatttcctg aatggttaaa ataaggacaa
    13081 gagaaaacat ggatatctat atccttgtgc caaaaaaacc actgccctcc ccagaccaac
    13141 ctgaggaaag cggtgattct tattttagga gttaggaatg aatacacgaa atcaatttag
    13201 ctgattattt tttgtttttc aagaattcat cgtattgttt ttgcatttcg ttcaatactt
    13261 tttcgtaggc accttcagat ttcaattttt ccatcaattc tggaatcgct ttatctgggt
    13321 ctacagtacc agtgttgata gctgtatcaa attgttgcat tgtgttagca atagctgaga
    13381 tttcagattt cacattgtca gtattgaaga taaatccaag cgctggagat tctttagctt
    13441 ctgccaattc tttcttagaa ttttcgattt gttggtctgt aacgttttcg ttgatgtaaa
    13501 ggatccagtt gttaccagtg ttccatccac ccatgtgagt gtttcctttg tagccatcaa
    13561 gaacgcgaac acggttttct ttaccttcaa ttttttccca gttcttgcct tctggaccgt
    13621 aaacaagacc gttcaaaagt tctgggttcg tattcaagag gttcaagatt tccattgatt
    13681 tttctttgtt cttagagttg tttgagatga caaagttagc aacttgtgtt gtttggtttt
    13741 tcttgatgaa gttagtgatt ggtttgattt ggatatcttt gttggcaaca cgtgaaagca
    13801 agctgttacc gtagtcagct ggtcctactg tttcttcacg aacgaaccaa gtatcttgtt
    13861 gaaggtcaaa tgaagtgtca cttgttgcga cgtcttttgg aatgtagcca gcttcataga
    13921 atttgtgaag agtcttcaag tgttctttga aacgaggcac ttcgtaacgg tttacaactt
    13981 tagtagtatc gccttcaagg tcaataacga atggaagccc gtttgctact gggtagtcaa
    14041 agttatcaga tgggatgaaa actttaccaa tagcaaatgg tactacgtct ggagcttttt
    14101 ctttgatttg tttcaagact ggctcaagag tttcgtaaga agtaacacct gaaatatcga
    14161 taccatattt ggcaaggaga gttccgttga aggcaaagtt ttgagatgat gctacgttgg
    14221 ctgcaactgg tacagcgtaa atcttaccat ttacagtatt acccttgata taagctggat
    14281 caagtgcctt gtaaaggtct ttaccttctt ttttgtacaa ttctgtcaag tcagcataag
    14341 cacctttttg agcatttaca atatagttat ctgcaaaggc gatatcatag ttttcaccag
    14401 atgatgtgat aactgacatt ttcttaccat agtcacccca gccaaggtat tggatatcca
    14461 atttggcacc aactttttct tcgatgattt tgttggcatt tgctaacaat tcatccaagt
    14521 tatctggttt gtcaccgatt tggtacattt tgataacagg tttgtcacct gaatcagcag
    14581 cttttttgct gttacctgtc aaatttccac aagcagcaag acctgcagcc aaagcgacta
    14641 cactagcaga tgcaaaagca tattttttcc agtttttcat gataaaaact ccttttttta
    14701 tttttaaact tataaacaat gtaatgatct taacttcacg caagggaagt ttggaaacaa
    14761 gtgctattct ttcacaccac cgatagtcaa accttttaca aagtagcgtt ggaagaatgg
    14821 atacaaaatt gcgattggaa gggttgctac cacaaccatg gccatacgac ctgtttcttt
    14881 cggtagagca actcccagtt gaccagtcaa gccgaccgct ttggcaatgt agtccatatt
    14941 ttgttggatt tgcatgagca aatattgcaa tggatacaag ttgtcactct tgatgtaaag
    15001 aagggcgttg aaccagtcat tccagaaacc aagagctgtc aaaagcgtga tggttgcgat
    15061 acctggtagt gacaatggca aacagatttg gaagaaaatc cgggcctcac tggcaccatc
    15121 gatacgagcc gattcgagaa tggcttctgg aatggtcttc ttgaagaagg aacgcatcaa
    15181 gatgatattg aatggtgaga gaagcattgg aacaatcaag gcccaaacag tgtcaccaag
    15241 ctgaagtaca cgggtcacca tgatataacc tggtaccaaa ccagcgttga acaacatact
    15301 gagaaggacg aagatggtaa aaaatctgcg atacttaaag gttgtccgtg aaatagcgta
    15361 ggcataggtt gttgtgataa agacatttgt caatgtccca actacggtta caaagacaga
    15421 gatgaagagg gcttgtagga ttttatcctt aaactgtgcc aaaaactcaa aaccgtctaa
    15481 gccaaattgg gatgggaaga agctatagcc gtattggagg aggcttttct cgtctgtcac
    15541 tgaaataatg ataacgaata caaaaggtag gatacaagag agggcaatca aacccgaaat
    15601 gatactgaag aagatatctg ctttcttact gaaggagtga atgccgacat tatcaatttt
    15661 ttctttttta attttctttt ttgccatatt ctcctccttt ctagaacaaa gctgagtttg
    15721 gatcgactcg tcttgcaagc aagtttgata ggataaccag aatcaaacca acaacggatt
    15781 ggtaaagacc ggctgctgca gccataccga tatctgctgt ctgagtcaaa ccattaaaaa
    15841 catatacgtc caaaacgttg gttacattgt aaagctgacc agcattgtgt gggatttgat
    15901 agaagagacc gaagtctgcg cggaagatat ttccgactgc aaggatggtc aatacagtta
    15961 caagcggagt caactgagga atggttacgt tgcgaatacg ttgccacttg ctagctccgt
    16021 ccactgtcgc tgcttcgtag taggttggat caattcccat gatcgtcgca tagtacatga
    16081 cactgctata tccaaaacct ttccaaatac ctaggaaaag taggagatag ggccagatgc
    16141 ccaggtcagc gtagaaattg acttctttga gaccaagact ttccaataga tgattgaaca
    16201 cccctttatc aatatttagg aaggcatctg taaagaaact gatgataacc caagacaaga
    16261 agtaagggaa caacatagaa gtttggaaaa tcttcaccat tctcttagaa cggagctcgc
    16321 tgaggataat ggcaatccct acagatacaa ctaaacctag aaagataaag ccaagattgt
    16381 agaggacagt atttcgtgtg ataataaagg cgtctcttga actaaataag aatctgaaat
    16441 tatcgagtcc gacccattta ctatttatga tactatctat gaaaccatta ctggtcatgt
    16501 ggtagtcttt gaaggcaacc acgttcccaa atactggaat gtaaaagaat agaatcaacc
    16561 agagtgcccc tggcaaaacc atcaagagaa agatccagtt gtctctcaat gtttttgaaa
    16621 actttttcat aatttcctcc ctttttattt tgatatccat ctaaaaattc ttttttagac
    16681 ttttgataac gattacatta ttagtatact cctatttgca ggttaggtta aactcctaat
    16741 tatagaaaaa attccacaaa ttatgtagca gatttaaaac tttatcacca ctatcaaaca
    16801 aatgtcctaa atcaattgtt tattttatct ctattagccc agtgatggcg tcactctgtt
    16861 ataagcatcc aacaacgggg tatactgaaa aatctccaga ctagggaact cagcgatagt
    16921 tcctaatctg gagattttta atatgttatt aggcgtttgc tttcaactta gcaataacct
    16981 ctttaagatt atcaatcaac tctgcttcag tatgctcaga gcctttttca tctgccaaga
    17041 acaaaactgc tttttgaagt tcttcttgag agttttcaag gacatcctta tctgctgttt
    17101 ctttgcccgc tgtttgtcct ccatccttag ttgctgactg gctttcctta atggactcta
    17161 gggaagcaat ggcatctttg actgtttgca agatatcacg taaaccttgc tctgtcaaac
    17221 tatcatctgt aagagctttc ttagcctctg ccaaaaccag acgtgctgaa tctgtggtag
    17281 gattcgatac acctgtcaat gatctcaaaa gattttctaa ggtttgagtc tgcttactaa
    17341 tactagacta aaatcaaaaa gcattacata acagtgatat gaaatcaact aaagaagaaa
    17401 tccaaaccat caaaacactt ttaaaagact ctcgtacagc taaatatcat aaacgccttc
    17461 aaatcgttct atagtaaaat gaaacaagaa caggacaaat cgatcaggac agtcaaatcg
    17521 atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatcc attatatttc
    17581 gtctgatggg caaatcttat aaagagatta tagagctttt at
//
LOCUS       DAVIME010000046        17541 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVIME010000046 DAVIME010000000
VERSION     DAVIME010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.046"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..1545)
                     /gene="phtB"
                     /locus_tag="VV588_001660"
     CDS             complement(<1..1545)
                     /gene="phtB"
                     /locus_tag="VV588_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU7083969.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVLKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDISSDKVKLVEDILAFLAPIRHP
                     ERLGKPN"
     gene            complement(1553..2470)
                     /gene="adcAII"
                     /locus_tag="VV588_001661"
     CDS             complement(1553..2470)
                     /gene="adcAII"
                     /locus_tag="VV588_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU7083970.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLAEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            complement(2613..4004)
                     /locus_tag="VV588_001662"
     CDS             complement(2613..4004)
                     /locus_tag="VV588_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU7083971.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            complement(4378..4935)
                     /gene="sdbB"
                     /locus_tag="VV588_001663"
     CDS             complement(4378..4935)
                     /gene="sdbB"
                     /locus_tag="VV588_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU7083972.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            complement(4946..5653)
                     /gene="ccdA2"
                     /locus_tag="VV588_001664"
     CDS             complement(4946..5653)
                     /gene="ccdA2"
                     /locus_tag="VV588_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU7083973.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDFNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            complement(5884..6288)
                     /locus_tag="VV588_001665"
     CDS             complement(5884..6288)
                     /locus_tag="VV588_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083974.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            complement(6330..6530)
                     /locus_tag="VV588_001666"
     CDS             complement(6330..6530)
                     /locus_tag="VV588_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7083975.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            complement(6697..7338)
                     /locus_tag="VV588_001667"
                     /pseudo
     CDS             complement(6697..7338)
                     /locus_tag="VV588_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(7552..9315)
                     /locus_tag="VV588_001668"
     CDS             complement(7552..9315)
                     /locus_tag="VV588_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU7083976.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            complement(9324..9914)
                     /locus_tag="VV588_001669"
     CDS             complement(9324..9914)
                     /locus_tag="VV588_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU7083977.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            complement(10012..10503)
                     /gene="rocS"
                     /locus_tag="VV588_001670"
     CDS             complement(10012..10503)
                     /gene="rocS"
                     /locus_tag="VV588_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU7083978.1"
                     /translation="MSIEMTVSEIAEILGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            complement(10580..11272)
                     /locus_tag="VV588_001671"
     CDS             complement(10580..11272)
                     /locus_tag="VV588_001671"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU7083979.1"
                     /translation="MKIGIIAAMPEELAHLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            complement(11289..11603)
                     /locus_tag="VV588_001672"
     CDS             complement(11289..11603)
                     /locus_tag="VV588_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU7083980.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            complement(11615..12160)
                     /locus_tag="VV588_001673"
     CDS             complement(11615..12160)
                     /locus_tag="VV588_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU7083981.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            complement(12170..13549)
                     /gene="glmU"
                     /locus_tag="VV588_001674"
     CDS             complement(12170..13549)
                     /gene="glmU"
                     /locus_tag="VV588_001674"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU7083982.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRCRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKGEYAT
                     RLPHHPRNQ"
     gene            13683..14483
                     /locus_tag="VV588_001675"
     CDS             13683..14483
                     /locus_tag="VV588_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU7083983.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQHPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSIWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            14578..15420
                     /locus_tag="VV588_001676"
     CDS             14578..15420
                     /locus_tag="VV588_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU7083984.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYSLNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNTGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            15420..15902
                     /locus_tag="VV588_001677"
     CDS             15420..15902
                     /locus_tag="VV588_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU7083985.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            15902..16522
                     /locus_tag="VV588_001678"
     CDS             15902..16522
                     /locus_tag="VV588_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU7083986.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPADRILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(16775..16870)
                     /locus_tag="VV588_001679"
                     /pseudo
     CDS             complement(16775..16870)
                     /locus_tag="VV588_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            17283..17541
                     /locus_tag="VV588_001680"
                     /pseudo
     CDS             17283..17541
                     /locus_tag="VV588_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5310 a         3686 c         3121 g         5424 t
ORIGIN      
        1 atttggtttt cctaaacgtt ctggatgacg aatcggagct aagaaggcaa gaatatcttc
       61 cactaacttg actttatcac ttgagatatc cttgagtcgt tccaacaggt tatccaaagc
      121 ctcaaaatca acttgtcgac ctttattatc aagtaaatct tggtgaattc ttgctagtaa
      181 gtcataagcc ttattgtaaa attctctatc actagatggg aggtcagttt tcttagctcc
      241 tagcttatga gataaacttt cctgcttggc cagtttgcta tcaatgcctg ctgctgtttc
      301 tgctgaaaga tccttggctg ggatataacg agaaactcca ttctcctcaa agacataacc
      361 atcgcctact tttcgaacag cttctttgac caatttctca tcaattggat tgcttggagc
      421 tggttgagga tttggtgcag gttgcagact tggactaggt tccggagtcg attgtggact
      481 tggttgttct ggtcttgaat ctggtaccca atggtttgaa cgataacgaa ggggaataat
      541 acgagcaatt cgtttttcca attcagacat ttgttcataa gggataaagt ggtaatggtt
      601 accatgaggg acagctacac ctctggcggt tcgacttgtg atttgcgctg ggtcgaaaat
      661 aaggccatca gattccacat ggcgttctga taagggttta gcatacaatt cacgtaaaag
      721 gcttgaaatg ttttcccctt gattttgatg ataagttgga gtgacagtca gattgtggtt
      781 ctctgacaat cttggttgag ctgtatttgc attataacta gaacttgaag aaggacgaga
      841 tccctgcttc ccattccaat aggcttgggc agcagctaac tcgctagctg ataactcatt
      901 cttaggaatg taatggtaat ggtcgccgtg aggaacgata taggcatcgc ccgtatcttc
      961 aatgatatca gatgcattga agatataccc atcatccgtt gtataacgtc cttgggctct
     1021 ggctgcagca acagcattat ctgctcttga gttatgatta tgactgcgtt cctgcttctg
     1081 acgtttaatc tcttcttttg tccgaatatt atccgcatga gctgcatcct taaggtaaac
     1141 atagtattta ccgtttacct taaggacata accacccttg atttcattga caatgtctga
     1201 atccttcaac tgataattcg gatctttcat gaggagctct tcactgatga tggcatcata
     1261 agggaccttg ccattatagt aatgataatg gtctccatga gaggtcacat aaccttgatc
     1321 cgtaatcttg atgacgattt gttcggcgtt gatcccctcc ctcttactga cttcatctgg
     1381 tgtcaagttt tctgcctttt gaccagcctg atcaccatct atataagcaa ctcgattaga
     1441 ctctttctta tcctgaccag cttggtaacg tccaagctca taggaacaaa cacttagggc
     1501 aagaactgcc accgaacctg ctagatattt tttattgatt ttcattcttt cctcacttta
     1561 attcttctgc tagaacactc atattttctt ccagattttc taaataggtc ttgtcatttt
     1621 gtgggtctgc ctctaaagga ttcagagttt taagacccac acctgttgat ttgacaagag
     1681 tttcagctac ttttgaagaa gcattacttt ctgtaaaaat cgttttaacc ttataggttt
     1741 taacaaattc ctgaatttct gctaattgtc gtggacttgg ttcttgttca ggagagatgc
     1801 ctgcaatacc aagttgatta agcccaaatc tcttcgctag ataagaaaag gctgtatgtt
     1861 gtgttacaaa tgttttctga gtcgcttttt caaattttgg ttggaatttc ttagtcaatt
     1921 cctgagcttt tttgataaag gcttgcgcat ttttttgata agtctcttta tgctcactat
     1981 ccacctctga aagtttatca gcgataattt gggcttcttc tccagctttt tcaggatcta
     2041 gccatgtgtg agggtcatag agcgtttttt catcaactcc atcccctgct tccacatcct
     2101 ctagtccagg gacacgttcc aaggtcattc cctcagaagc ctctaagacc ttcactttgg
     2161 atttttttag attgggatcc agacttcctg cccaagattc gagtgtatga gaatggtaaa
     2221 caaagacatc tgcatcatag atggctgcga tatcatttgc cgaaggttca aaggagtgaa
     2281 taccactact tgactgaatc atccgaacat cattcaagtc accagatact tccttaacca
     2341 tagcgtagat aggataaaaa ctggtcacaa ttttcatccc ctttcctgtc tgactttcct
     2401 tttgaccaca agcccccaag cacaaaagaa agacacttaa caggactaaa aataaatttt
     2461 gtttcttcat gaacaactcc ttaaccattt aattaactag taaatattct actcctgaaa
     2521 atttaatctg tcaagatatt tttagaaaaa atttgaaatt tctttcacat ataaaaatct
     2581 gctgagtgtc aacaactcaa tagactttca ctttattctt ctatggtaga atgcttatag
     2641 ccataagtga agtaaataat acttcctact aacaacgcaa ctaggaaagc aatccaggta
     2701 ttcatattat actgtaacat gaaggataaa caaatgatga tcgataaaat tggtaacaga
     2761 ggtaccaatg gtgttttaaa ttccccagct ttgggcattc ctttttcttt ccgtaagcga
     2821 atcagaccat aagccaacat gatcaagtag gctaaggtac aaatatttaa aaaggctgca
     2881 atactggcta gtgggaacat tcctgctgct actgctgaag ctagacctgt caagatagta
     2941 gcattctttg gtaccttgct agtcttcgtc agttccttaa aggcagcagg cactaagccg
     3001 tcacgtgcta aactgtaaat catacgcgat agggcatagg tcatcgaaat acaaactgta
     3061 atcaaggtca agatagccac taatgacaca tagttggctg cccaactaat cccaacacta
     3121 cgaagggcaa aggcaacggc atcatcgaca tttaaatgac tatagtgaac cacaccagtc
     3181 aaaacaaggg tcaccaaggc atagagaatg gttacgatag aaagcgataa gacaatccct
     3241 ctaggaatat ttttttgagg agtcttgact tcatctacag ccatagagat ggattcaaat
     3301 cccaaaaaac cgaagaacat caaggatgca ccagccataa taccagtact agctccatag
     3361 atttgtccaa aaccgtaagg agcaaaattg ctccaattat caaacttaat attccaaatt
     3421 cctactaaaa caaagagagc taaagcggaa aatttcaaaa taactagaat cgaattaaag
     3481 cgtaaggctg ccttggcatt tagtaaaaca agcgaagtca ccaagaccaa gacaagaata
     3541 ggcaataaat caacaaatgt ccctgcttga ggattaaagg taccatttaa agcctgagga
     3601 aaggctatcc cgtattgaga gagcaagcct ttaaaataag ctgcccaacc cgaagctacg
     3661 cctgatatgg ctgtcatgaa ctccatcatg gttaaccaac cagccaacca ggcagggaat
     3721 tctcctaaga tagcatagag gtaactatag gcacctcctg tagcgggtac tcgcgaggca
     3781 aattctgcaa aaaagagggc tgataatccc acacacaagg cagaaataac gattgaaatc
     3841 actagggctg ggccagcaag tgttgcagct gcagtacctg tgattgtaaa gacgcctgtc
     3901 cctaccatgg ctccgatacc cagcaaaatc aaatcccata acttcaaatg cctatgcatc
     3961 tctgttttat ctaaactaac attctttgtt ctaaatatat tcatctttga ctccaaaata
     4021 aactgataat tctattttac cataaatata ggagatatgt gaatatttat aaaatgtttt
     4081 tctaaaaaaa tctgactacc gtaacttctc aaagtaactt ccatctctct cccaaaactg
     4141 gaagttactc taagacgact ctgttttagg gctatttgtc gtgcactttt tctgagtctt
     4201 ttcgcttttg aacccttata tatcaagaaa aagaaaacca gtggaagtta gtctaagacg
     4261 gatttccact gatgtcacgc gtttttctca tactaaaagc taggttgtgg gaaactggaa
     4321 gttagtttta gaagttacca aaatctgact acatcttgta atcagatttt atcgattcta
     4381 gttcatttct ttaaatgctg cttctgcatc cgcattactg atagcaccaa attgaatctt
     4441 tccaatcttt ccttggctat caattaaata ttctgtagga atgcttcgaa tttgataagc
     4501 ttggaaggtg gttgctttgg tatcataaag aactgggata tccttatatc cttgttcctg
     4561 gaaccattgt gggaattgct caacagtttt ttcaccttga attcctggtg caatgacagt
     4621 aagaatttcg aaatcacgat ctggtttcgc cgctagttcc atcaactctg gcatactttt
     4681 cttgcatgga ccacaccatg aagcccaaaa cttcaagtaa acctttttac ccttaaaatc
     4741 agataactta acttctttgc catccatgga ttgcaatgta aagtctggag catcttttcc
     4801 aacagaaatt tgttgtacag tcgtttgttg ttttggctgt tgtgctgctt gagtcttttt
     4861 agtttcttcc tcaccacagg ccatcaatac aactaatgac aagagactta agccagcaaa
     4921 cattactttt ttcatttgtc ctcctttatt caaaaattcc agctagaaca tttacttgtc
     4981 ctaatagtaa caaaattccc attaaaacaa tgaggaaacc accaattttc tttagtagca
     5041 tcatatgacg cttgatttta ctaaaatatg gcatgactag acctgaagct agtgccaaga
     5101 ccaagaaagg aagggccatg cccagagtgt aaatgagagt ataaatcgct ccttgccaag
     5161 caccattgcc tccagaagcc gcaagtgcta aaacagaact taaaactgga ccaatacaag
     5221 gtgtccaacc aaagctaaag gtaataccaa gtaaaaaagc tgaccaataa cgattaaaat
     5281 ctgatttttt aaaggtaaaa cttttttgaa cttctaattt cttcaaatga aaaatttcca
     5341 tctggtgaag acccaaaatg ataataatag ctcccatgac atatcgaaac caatttgcat
     5401 agagaatatg accaaagtaa ccagcaccaa agcctagaat aaagaaaatg agagagatac
     5461 cagcgataaa gcaaagtgtt cgaatcaagc ctgaccagag aacctttctc ccaaacaaag
     5521 aaaagctttt tgcactttct tgatcatcca ataaaatccc agcatagact ggcagaagag
     5581 gaaaaataca aggagaaaaa aaggataaaa cacctgctag aaaaacagag attaaaaata
     5641 ctatcgtttc caataaagaa ccaactttct taataattct aatcctattt tactatattc
     5701 aattttattt gtaagctttc tgctacgcaa aatcgtatcg ggcactattg gaccaatctt
     5761 ttcttttgct agtcaaggcg gatcttatcc cccaaaatag ccaaaaagca acgacaagga
     5821 ttactcatcg ctgcttttgt gaacgaaaat gtcttttagg tctgacattt cataaatcat
     5881 gttttacttg agtttgtcaa ggattgcttt aagctcctct actagtttag tttctgtctc
     5941 tgctgagcca ttttcttctt tcacgaaatc aagggtttct tggagaaggt tttgggcttt
     6001 ggcaaggact tttttatccg ctttttctgc atctagctgt cctagaacct tgatcaattc
     6061 cgtgcttaat tgctggattt ctgactcttt cttacggcga atcagccaga aggcaatcac
     6121 gcctaggagg gcaagtagac tgaccacaat cactcctgcc ggaactgagt ttgtttcagt
     6181 catcttatct gaatccttac tatcttccgt tccttgtttt gcatccttct tgtcctgtgc
     6241 aggcttgctg tcgctagcat ttgctttcac atctttgaga gagtccaagg cagcccagcc
     6301 ttcacagact ctactgcagt atgcagacct tactctgtca aggcactatc ttccggagct
     6361 ttttgagcat ctaggaggac agccttggtt gcatcgattt tcggatcaga tactgttgcc
     6421 aaagctttca agcgttggtc taactcttga ctcaaggcac gaagttcaga cttgtcaact
     6481 tgctcttgag cttgtgtgct cgttgagcta gccgaagcgc ttgctaccac tctaggatct
     6541 tgagtcggag ctgagcttgg agctgggaca gggcttgcag gttgactagg aacagttatg
     6601 gtatattgaa actagaatag tacatatgga cttctaaaac attgttagaa ttcgatttta
     6661 ctgtcctgat cgatttgtcc tattcttatt tcattttact ataataaccg atggtgtggt
     6721 taatgttggt aagaaaaact tctgaaacca tacttcaaaa aagtcgctcg tcatcatctc
     6781 ttcgtaagtc attggagcga ttaattcacc atttgttaga cctgcaacca aagaaatcct
     6841 ctgatatctt cttccagata ctttgcctct tcttaactga ccttttaatg agcgaccata
     6901 ttctcgataa aaataagtat cgaatcctgt ttcatcaatc taaacaggtg ctaggtgctt
     6961 taaactatta aaattcttaa gaaataaggc tacttttctg ggtcttgttc atagtaggtg
     7021 tggttctttt tttcgagtgt agcccatagc tttgaacgca tagtggatgg tagttggatg
     7081 acagccaaat tcagaagcta tttcagtcaa ataagcgtct ggattgtcag taagatagtt
     7141 tttaagtcta tctctatcaa cttttcttgg ttttgttcct tttacttggt ggtttaactc
     7201 tcctgttttc ttttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac
     7261 gtgtgatgct tctgttatac tacctattcg ctcacaataa gagagaactt ttttacgaaa
     7321 atctattgaa tatgccataa gaagattata ccacattgtg tactattttt ggttcatttt
     7381 actatatttt ataagttata gtgtagcatt ccaacttcaa agcactataa agtaaattga
     7441 aacaagaaca atacaaacaa ttctcgtaaa cggattgcaa ccacaaaaaa gcaagcattc
     7501 acaagaatac ttacctatca tgggaggaac aaccgttcct cttttttatt actaaaattc
     7561 aaagaattcc aatgcttttt tcaagagcaa atccgtatat tctggatctt cttgggctac
     7621 ttctatttcc cgctgaactt tttccaaatc atctgtaatc actccatcta ctcctaagtg
     7681 aagagatttg ctgatagctt ctgaatcatt gacagtccag acataaagtt tctgatccgt
     7741 tgtccatagt ttgcttacaa aatattcatc caaggttgag tactccatag tatatcctgt
     7801 cgctcttgtt ttaggaaaga cagaattgta gggcatgatg aaataaactg gcagttcggc
     7861 atcatactgt cttacttttt cgacaacatg gtagtctaaa gactggattt gatgtccata
     7921 aatcttgagc tttgcagcat aacgggctaa aaagcggttc atcatgtctg gactatcttt
     7981 tttactggtt ttaatttcaa ttagtaattt ttgaccaagt tcgttggctc gactgagata
     8041 atcttcaaag cttgaaattt tagtctggta gccattttca aaaatatcaa tccctttaag
     8101 ctcctccaag tttaagtctt gaggactttt attgatacct gctagatttt tcaagttagc
     8161 atcatgcatc atgacaaact gcccatcttt tgtttcctgc acgtccgtct ccaccaagtc
     8221 tggtttgagt tgtgctgtag tttccaagga ctctactgta ttttgaatcc catttgcatt
     8281 ggaaacccct cggtgagaaa taagttgagg tagatgaacc atgggagcct ccagataaat
     8341 ataaccttct aaggcaaaga aaagactggc acaagtcatg acaccccatc gcacgatgtg
     8401 atctttttct ctcctaggaa gcatatccag ctcctttcct gtcaaaaatg aaacaaattt
     8461 aaccaaaaaa taagtcagag ccatataata gagattttta atcacgacaa aattcaaaat
     8521 accaagaatc agagactctc tctgagtgat atcatctacc aaagtttgag ccaataataa
     8581 agggatcaaa ggaagataaa ataataaatg tgctttgagc aagatgtaaa ataaattcca
     8641 agcataaaaa gtaactctct tcttggtttt ctccaagcta aacatcactg cttctcgaac
     8701 agtcagctga tcatatacaa tcttcggaag ggcaaacatc aatctgacag agacatagag
     8761 aaagataaga gatagaagta ggatgctcag ccaccacatc caatatctat cttctaaata
     8821 agcttggata aactctggaa tgacgatttt attaagataa taaatcttca gcattttccg
     8881 tataaaagga aacagcatag ctatatagaa aaagataaac aaggctttag cgcaagttag
     8941 ctttttcata aatccaaaac tttcatggaa aaccttgcgg atatactcaa ttagccttcg
     9001 cttttcatta tagaggagat gacgagcacc aataaagagg agtcctattt gaaaataagc
     9061 aaccagaagg ttaattacaa tcaaggctaa aaaagctaga ctaatcaatg gagaatgagt
     9121 aaggatggct aagacattgt tataggaaat aaaaagataa cctgtctgat ctaataagaa
     9181 gctagccaac catgaattga atggtaccca caaatactcc actatcataa aaatcaagaa
     9241 aaatagaaag aggattttat caagattgag gtaaatctgt ttaagaccca attttttagg
     9301 tttttcaggt ttcataggca ctcctagtca aataattgag acaagtccaa gccaccaaaa
     9361 ggattgtttg ataagctact ttctgtctct aacaattccc tagcttgatc cgactctaag
     9421 aaggattcgt aaacacgcgc cgtcatccga gcatcctcta aactattatg agactgacct
     9481 tgaaatccaa gaaatgaggc aacagtttgc aatttgagat tggcaatacc atgtaaatct
     9541 gaactccgac gttcaaaagc ttcatcatac aaatccacct tgtactgttg gctatagtct
     9601 aaaccatgct ctgctaaaat aggtaaatca cttttagcag cattgtagcc tatcatcagc
     9661 aaagaaccca caaactcttg gaattcttct aagactttct caactggagg agcatctttt
     9721 aaggtctcag ctgtaatccc ggtcaaacca ttgataaagc tttttagagg gacgctggta
     9781 tgaacatagg aatcataggc atcgatttcc cgaccatctc taaaacgcac tgccgatact
     9841 tgaatcaagt gtgtttgtcc ttcgtgctga ttaaattcta agtcaaaagc aatgtaatct
     9901 tctaatcgtt ccattctgta cctctcctct actgtctctg ttctaatcaa ctatactatt
     9961 cacaaacaaa agaagccatc aggttagcat ttaacctaaa cagctccttg attatcctcc
    10021 aaataaacga gcaaaaaagc cttttttagt ggattggact tcttcttttg cttggtccag
    10081 ctctagctta agattttctt gatccttcat ggcttgaagg gtcaattgtt gttgctgatc
    10141 taattgtttg tctttctcag caatctgacg gtctttgata cgcatctgct cgtctttttc
    10201 tgataactga cgatccttgg cttttaattg ttcataaaga cgaagaattt ctgcattctt
    10261 ctcatccact agaatctcca tcagttcacg ttgtttgaca tcttcactga caggttcatc
    10321 ttcaaaaatc gtttttttat agatttcttc tagcttaatc aagccacttc tggtaacaac
    10381 tgttacccct ttgtcatttt tatctgtgtc ttcttctggt aattctttga cacggttatt
    10441 gattgcttgg cgagataatc ctaagatctc tgcaatctca ctgacggtca tttcaatact
    10501 cataatatcc tctgaaacgt tttctagctt ttctttactt aaatcttatc ataagctaga
    10561 aaaactgtca aatttccgct taatctaaag ccttcaaaaa ggccaacaag acttgggcag
    10621 agcgacgtcc agcttcgata ataaactcat caaaaaagat gtttgcttca tggttggcat
    10681 tgtcactcat agctctgatg actaagactg ggagattgag ggcatgcgct gcttgagcaa
    10741 tagctgcccc ctccatctcc acggctaaaa cttctgggaa atgggactta atcgcttcta
    10801 tcttgtcatt tcctgcaaca aaactatctc ctgtagcaat caaaccaaga tgccagtttt
    10861 ggtccaattg agataaactc tcttggattt gagcaacaaa ggttttgtct gattcgaaat
    10921 aaagcggttg ttgcgccatt tgtccataag catagccaaa agctgtgaca tccacgtcat
    10981 gataggctaa tttgtcagca atcacgacat ccccaacagc gataccttct gctactgccc
    11041 cagctgaacc cgtattaata agggcatcca cctggaaatg atcagccaaa atcgccacac
    11101 tcatagcaga catgacctta ccaattccac tttctacaag aacgacttca tgagaagcaa
    11161 tggttcctgt atgataggta ttccccaaaa caacttgctc ctgggcattg tctaaatgct
    11221 ggaccagatg agccagttct tctggcatag cagcaataat tcctattttc atttcaattc
    11281 cttttctatt acaaaagttt cattgctaaa acaagcaaaa tcaagagaaa gatgaccgcg
    11341 aataagattt tattcaactt agaattgaag acatttctct tggtattttc aatgcgacgg
    11401 cttttatgaa tagatggttc gacctgaatc ttcaaggttt cctggctaaa accatgatcc
    11461 ttaggattgg cataaccaaa acgggaagaa gaggttggta aaatcttagt ttcctcatta
    11521 tcatccagca aaggaggacc tgaaattttt tcgcctctat tagctctttc aatcatttca
    11581 tccgttaata aagatttacc catactgacc tcctctattt tttctgcaac tcccaatact
    11641 gaacagccat aattgtcttg gcatcacaga tatgacctga ttggattaat tctttcgctt
    11701 cttctaagct cacttcaagg acttccaagg tttcatcctc atcctgcgga cgcggatttt
    11761 ccacttttgt caaatcgctt gctaaatata gttttaactt ctcattacaa aagccaatag
    11821 ctgaataaaa atcgtacaag agttctaatt tccctgtata ggctgtttct tcctctaatt
    11881 cacgaagggc agctgccaca ggggctgtgt tttctcctac ctccaatttt ccggctggaa
    11941 tttcgtaaga gacagcctcg atagctttgc ggtactgctt gaccaagata agtttttgtt
    12001 catccgttac tgctaaaaca cagacagccc cattgtggaa aatcaaatcc cgttgggcag
    12061 ttcccttgcc ttctggtaat tcaacctgat cttggaccag tttaaatatt ggtccttgat
    12121 agatttcttt tcggctaagc gttttttctt caaactccat gataggctcc tactggttcc
    12181 taggatgatg aggaagacgt gttgcatatt cgcctttatt gatctgacga ccgcgaccaa
    12241 tagcaatagc atctgctggc acgtctttag taatagttga accagcacca acgagggaat
    12301 tgtcaccaag ttctactggt gcaataatgg ttgaatttga accaacaaag acattgtctc
    12361 caatgactgt cttgtatttg tttttgccgt catagttgac tgtaatagtt ccagcaccga
    12421 aattaacgtt gcttcccact tcacagtttc cgatataagt caaatgacca gccttggtat
    12481 tctcaccgat tgaagatcct ttcacctcaa caaagttacc aatatgaact tgggcaccca
    12541 gacttgaatt tggacgaatg tgagcataag gaccgactgt cacaccgtct gcaacactac
    12601 tttcctcaat catagaattg gtaatgaccg ctcctgctcc gatagtgctg tccactacat
    12661 aagtaccgtt tgtcaaaaca gtctcagcac caattttcgt ttgccctttc aaggtaacat
    12721 tggcttcgat ttgaacttcc ggagcaatct caacatcaat atcgatataa gttgcttctg
    12781 gattgacaaa gctaacacca ttgaccatgt gtttatgatt gatgcgacaa cgcataactg
    12841 actcagctgt cgcaagcgcc acacggtcat ttaccccaag actttcatca aaatctttca
    12901 aagtataagc gccaactttt tcaccagttt cacggaaaat accaatgacg tctgtaatat
    12961 agtattcgcc ttgagcgtta ttggtattga tatttttcaa agcctcaaac aaacgctcgt
    13021 tgtcaaagac gtatgttcca gtgttgattt ccttgatttg cttttcaaaa tctgtagcat
    13081 ccttctgctc aacaatacga agaacctcag cattgtcatt acgaacaatt cgtccatagc
    13141 caaaaggatt atccgtttca gcagtcaaga tagtggccac atttttatga ttgatatgga
    13201 aatcaatcaa gtttttcaag ctttcaccag tgattaaagg agtatctcct gcaatgacca
    13261 aggtgtgtcc tgacaaacct tctaagatag gctctgtcat cataactgca tgaccagttc
    13321 ccaactgttc agattgagtc acaaattctg tctgtccagc caagacctcc tcaaccaatt
    13381 ctgccttgtg tcctacaact gttactgtct tttcaggttg gatagctccc acactacgga
    13441 aaacatgttc caacatagaa atacccgcaa ccttgtgcaa aacttttggc aaatcagatt
    13501 tcatgcgagt ccctttaccc gctgctaaaa taatggcaaa atttgacata atcttctctt
    13561 tcctgtagaa attccctttt attataccat atttcaaatc attccgcact cttgaatgaa
    13621 aaaatgctct aaagtctctt ccttaaccca tttttttgat ttttagggta gaattataag
    13681 atatgagaaa acaaattcat ccacttattt tatttagttt tttggggatt atgatgttca
    13741 ttttaatcat caatcgccca cttaatgaca accaatcgtt taaaacaaaa tccaatatag
    13801 cacagattga agcacaggct ttgaaacact tagacaaacc gattattgac ctctctggct
    13861 ggcagcatcc tgaggaaatc aactacgatg ccctctcaca aaatatttca ggtgctattg
    13921 ttcgtgttca cagtggtgct caaacgacaa aagaaaatga tgcttcattt atcaatggaa
    13981 tagacaaggc ctataagagt catatcactg aacttcaaaa gcggaatgtc ccagttgctg
    14041 tctacgctta tgtagctgga aaaagtgtcc aagaaatgga aaaggctgcc gaagttttct
    14101 acaatgctgc ctctccttac agccctagtt actattggct tgacgtggaa gacaaaacca
    14161 tgtctaatat gaacgaaggt gtcgaaaact ttcgagcaaa actagcatca ctaggtgcta
    14221 aaaacatcgg catctacgtt ggtgtctact tcatggaaga acacagtatt gatacaggca
    14281 agtttacctc tatttggatt ccgtcctacg gctcagactc aggatttttg gagagcagtc
    14341 ctaaaactga tttagattat gatattcacc aatacacatc taaaggaaaa attgccggct
    14401 ttgaccacga tttagatatc aacgttatct ctcccttaaa aaataaagaa gaaacctttc
    14461 gaaaactttt tttaaaacct taaaagcatt tgtttatcat ttgctttttc tttttgtgtc
    14521 tgattgtgat acaatatagt aaggattttt tgaaatagaa atagttggag gaaatatatg
    14581 ctctcatggt tagcacgcgt tattaaagga attgtgattg ctcttggatt tatcctaccg
    14641 ggaatttccg gaggggttct agcagcaatc ttaggaatct atgaacgaat gattggcttt
    14701 ctggctcatc cctttaaaga ccttaaagaa aatgttttgt actttattcc agttgccatc
    14761 ggtatgcttc tgggaatcgg cttattttcc tacccgattg aatacctgct tgaaaattat
    14821 caggtctttg tattatggag ctttgcggga gctattatcg gtacagttcc tagcctcctc
    14881 aaagaatcaa ctcgagaatc tgaccgagac aagattgatt tagcttggtt atggacaacc
    14941 tttatcattt ctggattagg actctattcc ttaaattttg tcgttggaac cttaagcgcc
    15001 agctttctta acttcgtcct agcaggcgca ctattggccc ttggcgtctt ggttcctggc
    15061 ctcagcccat cgaatttact tttgattttg ggactctatg ctcctatgtt gactggtttt
    15121 aaaacttttg atctcttggg aaccttcttt ccgattggaa ttggtgcagg tgcaactctc
    15181 atcgtttttt caaaattgat ggattatgcc ttaaacaact accactcacg cgtctatcat
    15241 ttcatcatcg gtatcgtcct atcaagtacc cttttgatct taattccaaa tacaggaaac
    15301 gctgaaagta tccaatacac aggactttca cttgtcggtt atgtcatcat cgccttcttc
    15361 tttgcgctgg gaatctggct tggtatttgg atgagtcaat tggaggataa atataaataa
    15421 tggcaaaaaa agttaaaatc aaaaaaacat tggtggaaca aatcctatct aaagcagcta
    15481 tccctcatca ggggattcaa atcaatgccc tagaaggaga gcttcctcaa ggttatgaac
    15541 gagatcagat tttcaaaacc ttggcgcttt tgggagacaa gaccggaccg attatcggaa
    15601 ttgtccctat cactcagcac ttgtctgaaa agaaactagc taaaatttct ggcaataaaa
    15661 aagtgagcat gattccacaa aaggacttag aaaaaacaac tggttacatt catggagcca
    15721 ataatcctgt cggaattcgt cagaaacaca attatcccat ttttatcgat aaaattgctc
    15781 tagatttgga tcgaatgatt gtctctgcag gcgaagtcgg acacagcatt atcgtcgcgc
    15841 cacaagactt ggctagcttt gtaaaggcag actttgtaga tattttggag gacatcaagt
    15901 aatgaaactc tactttgtcc gccacggtcg taccctctgg aaccaagaag gtcgttttca
    15961 aggtgctagc ggtgattctc ctcttcttcc tgaatccatt gaaaccctaa aacgacttgg
    16021 ccagtatctc aaggaaattc cttttgatca gatttattca agtgatttac ctcgagcggt
    16081 caaatctgct gagattatcc aaagtcaact ccataccccc tgttctttag aaatcgttcc
    16141 taatctccgt gaatggcaac ttgggaagtt agaaggtttg aaaattgcaa ccttggaagc
    16201 tatttacccg caacaaatcc aggcttttcg ttcaaatctt gctcaatttg acactcgaat
    16261 gttcggagcc gaatccctct atagtacaac tcagcggacc atccaattta tcaaatcatt
    16321 aaaagatagt ccagctgatc gtattctaat tgtcggacac ggcgccaatc ttactgccag
    16381 tcttcgtact ctcctaggct ataaagaacc acttcttcgt aaagatggcg gtctagcaaa
    16441 tgccagcctg accattatag aaacccatga ttttgaaaca ttcactctca atacttggaa
    16501 tgatacttct tatcaatcat aattatagcc tagccttctg aactagaacc ataggagata
    16561 tagtcagttg aaacaaaaat aagacaaaag aaccttgtaa aaaggtattg caacttgcca
    16621 ataccttttt gatatgaaca cgtgtcttct caacaggatt gtagagcaaa atgaaataag
    16681 aactgaataa tatgatttga gaatttaaat caatttataa gaatgtttta gaagcagtta
    16741 tgtactattt tagattcact tttctatact aagatgagta gggaggaaaa ggtaaaagtt
    16801 tatgcccaaa ttcttcacat aagaactcta gcttacccat tctatggaat cttgcattat
    16861 ccattaaaac ttccagactc atacccttct aaaatctatt caaaccacgt cagcttcaca
    16921 ttatatatgt tggtgacctc acaagtttta tctacaacct caaagctgtt ctttgagcag
    16981 cctacagcta gcttcctagt ttaatctttg cttttcactg agtatcaagt taaaaaaatg
    17041 aggctggtca aaaagtcttt aaaataaaaa acgcatatta tcaggtgtta aatgaactgc
    17101 accccaaaag ttagacagaa aaaatctaac ttttggggtg tttttattat gaaattaact
    17161 tatgatgata aagttcagat ctatgaactt agaaaacaag gatatagctt agagaagctt
    17221 tcaaataaat ttgagataaa caattctaat attaggtaca tgattaaatt gattgatcgt
    17281 taatgttgga acaggcattc aaagagaagc actacgagaa tacgattctc catagtgacc
    17341 aaggctggca atatcaacac gattcttatc atcggttcct agagagtaag ggaattcaag
    17401 catctatgtc acgcaaggga aacagccaag acaacggtat gatggaatct ttctttggca
    17461 ttttaaaatc cgaaatgttt tatggctatg agaaaacatt taaatcactt aatcaattgg
    17521 aacaagccat tatagactat a
//
LOCUS       DAVIME010000047        17425 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVIME010000047 DAVIME010000000
VERSION     DAVIME010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17425
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.047"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..702
                     /locus_tag="VV588_001681"
     CDS             <1..702
                     /locus_tag="VV588_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU7083987.1"
                     /translation="PAPKPAPAPKPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGS
                     WYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWLQYNDSWYYLNTNGAMATGWLEYN
                     GSWYYLNANGAMATGWLEYNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAK
                     VNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKANQWFKVSDKWYYVNGLGALAVN
                     TTVDGYTVNENGEWV"
     gene            1103..2224
                     /gene="mnmA"
                     /locus_tag="VV588_001682"
     CDS             1103..2224
                     /gene="mnmA"
                     /locus_tag="VV588_001682"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU7083988.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLKKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            2365..2820
                     /locus_tag="VV588_001683"
     CDS             2365..2820
                     /locus_tag="VV588_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU7083989.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2830..4743
                     /gene="mnmG"
                     /locus_tag="VV588_001684"
     CDS             2830..4743
                     /gene="mnmG"
                     /locus_tag="VV588_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU7083990.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWASFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4938..6617)
                     /locus_tag="VV588_001685"
     CDS             complement(4938..6617)
                     /locus_tag="VV588_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU7083991.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6619..6852)
                     /locus_tag="VV588_001686"
     CDS             complement(6619..6852)
                     /locus_tag="VV588_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU7083992.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(7670..7822)
                     /gene="cibB"
                     /locus_tag="VV588_001687"
     CDS             complement(7670..7822)
                     /gene="cibB"
                     /locus_tag="VV588_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU7083993.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7824..8009)
                     /gene="cibA"
                     /locus_tag="VV588_001688"
     CDS             complement(7824..8009)
                     /gene="cibA"
                     /locus_tag="VV588_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU7083994.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8187..8870
                     /gene="tsaB"
                     /locus_tag="VV588_001689"
     CDS             8187..8870
                     /gene="tsaB"
                     /locus_tag="VV588_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU7083995.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8867..9304
                     /gene="rimI"
                     /locus_tag="VV588_001690"
     CDS             8867..9304
                     /gene="rimI"
                     /locus_tag="VV588_001690"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU7083996.1"
                     /translation="MIEIKRIQQQPALAQDIYAVMAAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLTVQETLFEAEVLQIAVKGACQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            9294..10304
                     /gene="tsaD"
                     /locus_tag="VV588_001691"
     CDS             9294..10304
                     /gene="tsaD"
                     /locus_tag="VV588_001691"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU7083997.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10344..11650)
                     /locus_tag="VV588_001692"
                     /pseudo
     CDS             complement(10344..11650)
                     /locus_tag="VV588_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11926..12277)
                     /locus_tag="VV588_001693"
                     /pseudo
     CDS             complement(11926..12277)
                     /locus_tag="VV588_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12384..12677)
                     /locus_tag="VV588_001694"
                     /pseudo
     CDS             complement(12384..12677)
                     /locus_tag="VV588_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12920..14126
                     /locus_tag="VV588_001695"
                     /pseudo
     CDS             12920..14126
                     /locus_tag="VV588_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            14119..14915
                     /locus_tag="VV588_001696"
                     /pseudo
     CDS             14119..14915
                     /locus_tag="VV588_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            15002..16618
                     /locus_tag="VV588_001697"
     CDS             15002..16618
                     /locus_tag="VV588_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7083998.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRIATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16638..17425
                     /locus_tag="VV588_001698"
                     /pseudo
     CDS             16638..17425
                     /locus_tag="VV588_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         5303 a         3052 c         3847 g         5223 t
ORIGIN      
        1 ccggctccta aaccagctcc agctcctaaa ccagaaactc caaaaacagg ctggaaacaa
       61 gaaaatggta tgtggtactt ctacaatacg gatggttcaa tggcaacagg ctggctacaa
      121 aataatggct catggtacta cctcaacgct aatggtgcta tggcaacagg ttgggctaaa
      181 gtcaacggct tatggtatta cctcaacagc aatggcgcta tggcgacagg atggctccaa
      241 tacaatgatt catggtacta cctcaatact aatggtgcta tggcgacagg ttggctagaa
      301 tacaatggtt catggtacta cctcaacgct aatggtgcta tggcgacagg ttggctagaa
      361 tacaatggct catggtacta cctcaacagc aatggcgcta tggcgacagg ttggctccaa
      421 tacaatggtt catggtacta tctaaacgct aacggcgcta tggcaacagg ttgggctaaa
      481 gtcaacggtt catggtacta cctcaacgct aacggttcaa tggcaacagg ttgggtgaaa
      541 gatggagata cctggtacta tcttgaagca tcaggtgcta tgaaagcaaa ccaatggttc
      601 aaagtatcag ataaatggta ctatgtcaat ggcttaggtg cccttgcagt caacacaact
      661 gtagacggat atactgtcaa tgaaaacggt gaatgggttt aagccgatta aattaaatca
      721 tgttaagaac atttgacatt ttaattttga aacaaagata aggttcgatt gaatagattt
      781 atgttcgtat tctttaggta cctatcttat gatttcagga aatgtcatta aaaaaacgac
      841 tccttttctc taacttgaaa aatagattag agaaaatggg ttgttttatt tattatagtt
      901 atttgaatga agataagaag aaggtatact cacatcattc acataatctg tatattgact
      961 ataagtttta aaaaacaatt tttaagctct tccttgtctt ctctaaccaa gcgtgttata
     1021 atgaatactg ctcaagcgac cttcaatcgt gaagcacaca cgaccttcaa tcgtgaataa
     1081 acgaatagat gggagactta ccatgagtga taactctaaa acacgtgttg tcgtggggat
     1141 gagtggtggt gttgattcgt cggtgacggc tcttttgctc aaggagcagg gctacgatgt
     1201 gatcggtatc ttcatgaaga actgggatga cacagatgaa aacggcgtct gtacggcgac
     1261 cgaagattac aaggatgtgg ttgcggtggc agaccagatt ggcattccct actactctgt
     1321 caattttgaa aaagagtact gggaccgcgt ttttgagtat ttcctagcgg aataccgtgc
     1381 agggcgcacg ccaaatccgg acgttatgtg caacaaggaa atcaagttca aggccttttt
     1441 ggactatgcc ataaccttgg gggcagacta tgtagcgact gggcattatg ctcgagtggc
     1501 gcgtgatgag gatggcactg ttcacatgct tcgtggcgtg gacaatggca aggaccagac
     1561 ctatttcctc agccaacttt cgcaagaaca acttcaaaaa accatgttcc cactaggaca
     1621 tttgaaaaag cctgaagttc gaaaactagc agaagaagca ggtctttcga ctgctaagaa
     1681 gaaagactcg acagggattt gctttatcgg agaaaagaac tttaaaaact ttctcagcaa
     1741 ctacctgcca gctcagcctg gtcgtatgat gactgtggat ggtcgtgata tgggcgagca
     1801 tgctggtctt atgtactata caatcggtca gcgtggcgga ctcggtatcg gtgggcaaca
     1861 cggtggtgac aatgcccctt ggttcgttgt cggaaaagat ctaagcaaga atattctcta
     1921 tgtaggccaa ggtttctacc atgattcgct catgtcaacc agcctagagg ctagccaagt
     1981 ccactttact cgtgaaatgc cagaagagtt tacgctagaa tgtacggcta aattccgtta
     2041 ccgtcagcct gactctaagg tgaccgtcca tgtcaaagga gacaaggcag aagttatctt
     2101 tgcggaacca caacgcgcga ttacaccagg acaggcagtt gtcttttacg atggcgaaga
     2161 gtgtctaggt ggcggtttga ttgacaatgc ttaccgcgat ggacaagttt gtcagtacat
     2221 ttagattgac aaattttctc aatttgctac aataataaca gcaatagaaa tgatggtcaa
     2281 agctcatgga tgttgcaggc ttttttgtcc tgcacttctt tggagttttg actgtttttg
     2341 tgtcgtttaa gggaaaggac aagaatgact caacaagact ttcggacaaa agtagacaat
     2401 acggtttttg gtgttcgggc gacagccttg attgtccaaa atcacaagct tctagtcacc
     2461 aaagacaagg gcaagtatta cattatcggc ggtgcgattc aagttaacga aaaaacggaa
     2521 gacgcggtag tccgtgaagt gaaggaagaa ctgggtgtta aagctcaagc tgggcagcta
     2581 gcttttgtgg ttgaaaatcg ttttgaagtg gacggcgttt cctatcacaa tatcgagttt
     2641 cattatctgg tggatttgct tgaagatgcc ccgttgacca tgcaggaaga tgagaaaagg
     2701 cagccctgtg agtggattga cttggataag cttgaggata tccagctagt tccagccttt
     2761 ttaaaaacag ccctaccaga ttgggaaggc caactaagac acattcatct tgaggaatag
     2821 gagagaaaca tgacttatca ttttactgaa gaatacgata ttattgtaat tggtgcggga
     2881 cacgctgggg ttgaggcttc cttggccgct agccgtatgg gctgtaaggt cctgcttgcg
     2941 accatcaata ttgaaatgct ggctttcatg ccttgtaatc cctctatcgg tggttctgcc
     3001 aaggggattg tcgtgcgtga agtcgatgcc ctcggtggcg agatggccaa gactattgac
     3061 aagacttaca tccagatgaa gatgctcaac acagggaagg ggccagctgt tcgtgctctt
     3121 cgtgcgcagg ctgacaagga actttactct aaggaaatgc gcaagacagt tgaaaatcaa
     3181 gaaaatctga cccttcgtca aaccatgatt gatgagattt tggtggaaga tggtaaggtt
     3241 gtcggtgtgc gtacagccac ccatcaagaa tatgctgcta aggctgttat tgtgacgaca
     3301 gggactgctc tccgtgggga aattatcatc ggagacctca agtactcatc aggtcctaac
     3361 cacagcttgg cttctattaa cctagctgac aatctcaagg aactgggtct cgaaatcggt
     3421 cgtttcaaga caggaacccc tccacgtgtc aaggcctctt ctatcaacta cgacgtgaca
     3481 gaaatccaac caggagatga agcacctaat cacttctcat acacttcacg tgatgaggat
     3541 tatgtcaagg accaagtacc atgctggttg acctacacca atggtaccag tcatgagatt
     3601 atccaaaaca acctccaccg tgcgcctatg tttacaggtg tggtcaaggg agtggggcct
     3661 cgttactgtc cgtcgattga agacaagatt gtgcgctttg cggacaagga acgtcaccaa
     3721 ctcttccttg agccagaagg gcgcaatact gaggaagtct atgttcaagg actttcaacc
     3781 agtctgcctg aggatgtcca gcgtgacttg gttcattcca tcaaaggttt ggaaaatgca
     3841 gagatgatgc ggacaggtta tgctattgag tatgatatgg tcttgcctca tcagttgcgt
     3901 gcgactttgg aaaccaagaa aatctcaggt ctcttcactg ctggtcagac aaatggaaca
     3961 tcaggttatg aagaagctgc tggccaaggg attatcgcgg gtatcaatgc ggctctgaaa
     4021 atccaaggca agcctgagtt gattttgaag cgcagtgacg gttatatcgg ggtgatgatc
     4081 gacgacttgg tgaccaaggg aaccattgaa ccctaccgtc tcttgacaag tcgtgctgaa
     4141 taccgtctca ttcttcgtca tgacaatgct gatatgcgct tgactgagat gggacgcgag
     4201 attggccttg tggatgatga acgctgggct agttttgaaa tcaagaaaaa tcaatttgat
     4261 aatgagatga aacgcctaga cagtatcaaa ctcaagccag tcaaggaaac caatgctaag
     4321 gttgaggaaa tgggcttcaa gccgttgaca gatgcggtga cagccaagga attccttcgc
     4381 cgtccagaag tttcttacca agatgtggtg gccttcatcg gaccagctgc agaagacttg
     4441 gatgacaaga ttatcgaatt gattgaaaca gaaatcaagt acgaaggcta tatttccaaa
     4501 gccatggatc aggttgccaa gatgaaacgt atggaagaaa aacgcattcc agccaatatc
     4561 gactgggatg acatcgattc tattgcgacg gaagctcgtc agaagttcaa actcatcaat
     4621 ccagaaacca tcggccaagc cagccgtatt tcgggagtaa acccagcaga tatttctatt
     4681 ttgatggtgt atctggaagg taaaaatcgt agtatttcta aaactcttca aaaatcaaaa
     4741 tgatacgtcg tcggcttctt acgaatgagt tcaaagcttg gctttgattc atctccaacc
     4801 tcccatagtt ccccgaacta tgggagctaa ctcaagttat gcattttcct agccttctgg
     4861 tctgattttc attgagtttt aatctcaaaa gaaagcatag agaaaaacag ctccgaagac
     4921 ggggctgttt tcttgcttta ttcttcatct ggtgtgagga tcatcgggat gatgatcggt
     4981 tcacgttcgg tattttcata gaggaagggg cgaatagcgt tgacaatggc accattgaca
     5041 gattgcacgc tagcatcctt atttttcagt gcgatacgaa tggcattgaa gaggatacgc
     5101 tggctttggc gaatcaagtc gccagactct ctcatgtaga caaagcctcg gctgaggatg
     5161 tctggaccag atagaatcat ctgcgatttg aagtcaacag ttgcgactgc cagaacgaca
     5221 ccgtcttcag atagatcgcg acgatctttg aggacagctg cgccaatttc accgatacga
     5281 tttccatcga catagatatc ttgggcgttg aaatgacctg cgatacgagc tgagtcagca
     5341 gtaagggcaa gcacatcgcc attgctcatg ataaagatat tgtccttctc aacaccagta
     5401 tccactgcta gtccagcgtg gactttttgc atgcggtatt caccgtggac aggcatgaag
     5461 tattttggct taatcaagca gagcatgagt ttttgctctt gctgaccacc gtgtccagat
     5521 gtatggatat tgttcacttt accgtggata acttcgacac cagcttcaga aatgatgtta
     5581 atcagcttgt tgacgctagt agtgtttcca gggatgggac tagaagagaa gataacggta
     5641 tcacctggtt gtaattgtac ttgacggtgg gttccgttgg cgatacgaga gagggctgcc
     5701 ataggctcac cctgactacc tgtacagagg ataagaactt ctcctgcagg ataatctttg
     5761 atttcatttg gctcgataaa ggttccctta ggagctttga tgtagccaag atcgattccg
     5821 ttgacaatgg ccttttccat agaacgacca aagaccgcaa tcttgcgtcc agtcttaaca
     5881 gcagcttctg ttgcctgctg gagacggaag atatttgagg caaaggatgc aaagatgata
     5941 cgtccttcaa taccttggat aatcttcata atggactgac caacgacttt ttcagagttg
     6001 gtaaaggttg gtacttccgc atttgtcgag tcagacagga gacagagcac gccttcttca
     6061 ccaagcgcag ccatacgatg caagtccgca ggttctccaa ctggagtaaa gtcgaactta
     6121 aagtcacccg tacagacgat tttcccttga ggagtatgaa tgacaatccc caaaggctct
     6181 ggaatagagt gagtcgttct aaagaaagtt gccttgagat ttttaaaggt caactcggtg
     6241 ttgtggttga tttcgtaaag tttggcgttg cgcaagaggc cgtgttcttc gagtttccca
     6301 cggatcaaag ccaaggcaag cggtccagca taaataggga catttgcttg cttgagtagg
     6361 aacggaatcc caccaatgtg gtcctcgtgt ccgtgtgtga ttaaaacagc cttgacgcgg
     6421 tcgatattgt ctacgatgta agagtagtca ggaatgacat agtcgatacc aagcaagtca
     6481 tcttctggga atttaatccc agcatcgacg atgataatct cgtcttggta ttcaattccg
     6541 taagtgtttt tcccgatttc tcctagacca ccgatggcaa aaacgccgac ttcttcaggt
     6601 ttaagagtgt aggccatatt agaactccgt gatttcgaag gcgccagttt ctttttcgta
     6661 atcgagcaat ttgtcagaca agagttcgat atattcgata ttgtactctg ggcgattttc
     6721 ttcgacaagt tggcgagcag tgatgcgacc ctcaagttct gagctggcat cgatgtctag
     6781 gtaaagcgcg cgtgttgttt cacggcgtgg gctacgttct tttgtttctt gataaaaaac
     6841 tttgtaaatc atatagttcc tttctattta caggtcagct tattccaaac ttttagcaga
     6901 tatttgcttg atttcattcc attttgtgtc tagattgacc ttgattcgtt acaattattt
     6961 caattatacc acaaaatgaa aaattagtaa aagacggaaa cgagaaagtt agggggcgat
     7021 ttctttggta agcgtttgca aaaataaaga aaatgtgtta tgttgataac ggaagtgaag
     7081 tttattactt gtcataattc catatagatt ttaagtcaag gaggttgccc tatgtataac
     7141 ttatttgctt ttgctatcgg agttcgtttg ctagctttta tcgtttttgt tgcttgcgtt
     7201 tatggaggaa atcttctatt tgccaaactg gaacgatgac aaaccaagtt cttgtggaaa
     7261 attacctttg tgactctcta ctcgcttttt ctcctcctcg tgacctatgt cgtttggttt
     7321 gtattttact ttggattaaa tgcttagatg ccctgcttat gctggttttt tttgtttggg
     7381 aatgtagaga tagtagattt acgacacgaa aattccaccc catctatcaa gatgaggtgg
     7441 tctttgcatt tttctaacat gacatgacaa tggaattttc aaagcttatt atttttatgg
     7501 gagtcattgt tctactcaaa aatagagttg aagcataaaa ataaaacaat acaaacagat
     7561 aaatcgaatg gtaaagggat ggtagtaatg ttcaaatcat tgagaatgct gagcaaactg
     7621 taagagatga agacaataaa atttatcctt ctaaaaatgt gtttcttatc tagcatgact
     7681 taccaaactt tttacgaagg tcttttccaa tggtataacc tgccataaat aaagcgatac
     7741 caacaccgac accaaagcca cccttgattt cttgcaattc cttattagaa atttcacgat
     7801 aattgttcaa atctttcatc atattaatct cctcctaaaa aataaccagc tgccaaacca
     7861 gaacctataa gtgctgttcc acctgcaata gccttccaag atactgctac tccaaagata
     7921 accaagggag cgagaccgcc atcaatatct gataattcat tttcagataa ggataaaaat
     7981 tgattgtcaa gaatgtcaaa atttgtcatt gaactttcct ccttttttct tgttcacttt
     8041 tatattcgga aaagaaaagg aaaagtgagc atttttttaa attattttta gttaagtgag
     8101 ggcactcttg tctgggggca aagaaaattc ccatgtgcca gcttttgtag tataatagta
     8161 agcagacaaa aagataggaa tgtgttatga aagtattagc ttttgatacg tccagcaagg
     8221 ctctttctct ggctatttta gaggataagc aggttcttgc cgagacgacg attaatatta
     8281 agaaaaatca cagtattact cttatgcctg ccatcgattt tttgatggca agtttggatt
     8341 ggacacccaa ggatttggac cgaatcgtgg tagctgaagg gccgggtagc tatacaggct
     8401 tgcgaattgc ggtagcaact gctaagacct tagcttacac cctgaacatt gagttggttg
     8461 gtatgtctag tctcttggct ctagtgccat atcaacaaga aggtttgttt gttcctttga
     8521 tggatgcgcg tcgcaataat gtttatgcag gattttatga aaatgccaaa cctgtcatgg
     8581 cagaagcaca tctgcctttt gagcgagtca ttgagctaat caagggcgct agtcaggtaa
     8641 cctttgtcgg agaagttggc ccctttgttg agcagattca aaaacacttg ccaaggactg
     8701 attacaaaga aacattgccc aatgcagcta atctagctct tttggcctgg gacaaggaag
     8761 cagactcctt gcatgatttt gtgccaaatt acctcaaacg tgttgaggca gaggaaaact
     8821 ggctcaagaa ccataccgag tctggtgagt cttacattaa acgcctatga tagaaatcaa
     8881 acgtatccaa cagcaacctg ccttggctca agatatctac gctgtcatgg cagctgttta
     8941 cccagtcagt ccttggacac tagaacaaat ccaagcagat ctgtcccaag accagacttg
     9001 gtatgctctg gcctatgatg gggcagaagt gattggcttt ctaactgttc aggagactct
     9061 ctttgaagca gaagtcctgc aaatcgctgt caaaggagcc tgtcagggtc agggaattgc
     9121 gtcagccttg tttgctcaat tgccgacaga caaggaaatt ttcctcgaag ttagacagtc
     9181 aaatcaacga gcgcaagcat tttacaagaa agaaaaaatg gcggtcatcg ctgagcgaaa
     9241 agcctactac catgacccag tcgaggacgc cattatcatg aagagagaaa tagatgaagg
     9301 atagatatat tttagcattt gagacatcct gtgatgagac cagtgttgcc gtcttgaaaa
     9361 acgacgatga gctcttgtcc aatgtcattg ctagtcaaat tgagagtcac aaacgttttg
     9421 ggggcgtagt gccagaagta gccagtcgtc accatgtcga ggtcattaca gcctgtatcg
     9481 aggaggcgct agcagaagca gggattacag aagaggacgt gacagctgtg gcggttacct
     9541 atggaccggg cttggtcgga gccttactag ttggtttgtc agctgccaag gcctttgctt
     9601 gggcacatgg acttccgctg attcccgtta accacatggc tggccatctc atggcggctc
     9661 aaagtgtgga acctttggag tttcccttgc tagccctctt ggttagcggt gggcacacag
     9721 agttggttta tgtttcggag gcaggagatt ataagattgt tggggaaacc cgtgatgatg
     9781 cggttggtga ggcttatgat aaggtcggcc gtgtcatggg cttgacctat cctgcaggtc
     9841 gtgagattga cgagctggct catcaggggc aggatattta tgatttcccc cgtgccatga
     9901 ttaaggaaga taatctggag ttctccttct caggtttgaa atctgccttt atcaatcttt
     9961 atcacaatgc cgagcaaaag ggagaaagcc tgtctacaga agatttgtgt gcttccttcc
    10021 aagcagcagt tatggacatt ctcatggcaa aaaccaagaa ggctttggag aaatatcctg
    10081 ttaaaaccct ggttgtggca ggtggtgtgg cagccaataa aggtctcaga gaacgcctag
    10141 cagccgaaat cacagatgtc aaggttatca tcccccctct gcgactctgc ggagacaatg
    10201 caggtatgat tgcctatgcc agcgtcagcg agtggaacaa agaaaacttc gcaggctggg
    10261 acctcaatgc caaaccaagt cttgcctttg ataccatgga ataaagagtg gctctttgtc
    10321 aagtgtagtg ggtaggcgaa aagctacaat ctggagagta cgaaattcgt actctctttt
    10381 ttgatgttca aagtcatcaa aatccgtttt ttaaaattgt taaagttccg gaaaccaaag
    10441 gctttgcgct tgataatctt aatcaaatta ttggtcgctt caagtttagc gttggaataa
    10501 ggcagcttaa gtgcgttgat aatcttatct ctatccctta aaaaagtcca aaagaccgtt
    10561 tgaaaaagcg gatgaaccgt tggcagttct tgctcaatca atccaaagaa atggtcggca
    10621 ttcttctctt gaaaatgaaa gagcaggagt tgatagagtt cgtagtgaac ctgtaatccc
    10681 tcagagtaag aaagcagctt atctcgtact tcccgatggg ttaagtgcat tcgaaacgtg
    10741 ggctgataga atcgtttctg acagagcttg aagctatact ggtgtagtaa atcagtccag
    10801 tggactgatt tagcccgagc ctagaaacga aaaagcgagg gttccaaaag cgcttgagcg
    10861 cccgatactc caaggatttt cggtcaaatt ggttcatgat ttggattcgt actcggttca
    10921 tagctcggct cagatgttgg acaatgtgga agcggtcaag aacaatcttc gcctttggaa
    10981 agagttgctt agcgagccga taataagggc tgtacatgtc catggtgatg acctcgacca
    11041 gctcccgaac ctctctctga tagcgttgga aatggtttcg aatcaccgca tgagttcgcc
    11101 cgtctaaaat tgcgaggatg gatttggact caaaatcttg ggcaatgaag ctcattttgc
    11161 tctttttgaa gctatactca tcccaactca taacttttgg caacttggtc caatcggttt
    11221 caaacttaaa ttccctcagt tttcggatga cggtggaagt tgagaccgcc aatctgtggg
    11281 caatctcagt catagactgc ttttcaagga ggagctgagc gattttttgt ctcaccatgt
    11341 tggaaatctg gcaatttttc ttgacaatgg atgtttgaga aacgaccacc ttaaggcaat
    11401 tcttgcactg aaagcggcgc tttttgagat gcagtaccgt gggtaaaccc tgacagtcga
    11461 gaagcggaat tttagaggct ttctggaagt cgtatttgat catcttccct tgacaatgag
    11521 gacaaggagg agcgggggaa tccaactttg cctgaacgac tagatgggtt tggtatttca
    11581 gaacagacaa gattttgata tttttgtctt ccaatccgag caaatctgtg gtattcttaa
    11641 gttgttccat atgaaccctt tctaatgagt tggttagacg cttttcatta taggtcatat
    11701 ggggcttttt ttctacaaga aacgacccta taattcctgg ggtgggatta cccactacag
    11761 aaattataga gccaaagcat tccaaagtct tgtctgactc tggaatgttt tctgttcaca
    11821 gttgttttgt aactgcctaa taagtaaccg cgctataacg aggtatctac cgagattgtc
    11881 aattctccag tatactgtta taaaaaacaa aactggagga tttttttatg tccccccatc
    11941 gtcccatcga ctgttccgta gctgcccaat aacggagtat agtcggctga aacaagaata
    12001 ggacaaaagt gcctcaagaa aagcatcgta atttgacaat attattctga gatgtttttg
    12061 atgtaagccc atattttctc aatgggatta tactcgggtg aataggtagg aagtggtaac
    12121 agtctatgcc ctgctcctta cacatgttca ttctgtgaaa ccttgcatgg tccataatga
    12181 taagggatgg tgtatctaaa gtaggtagta agaatttttg gaagcaagct tcgaaaaagt
    12241 cactcgtcat cgtatcttta taggtcatcg gagccatagt atattgaaac aaaaaagggc
    12301 attagtactt ctataacagt atcgcaatct ctggtgtgcg ttgtctcgat cttaattcaa
    12361 ataattatat cttcttccag agagactaac tgcctgctca aggctcgatc atattcgaga
    12421 taaaaatagg tctcaacccc tgtctcataa atataaatag gagtcaggta gcttaagtga
    12481 ttcaattctt taaggaaccg atttactttt tctgggtctt gttcgcagta ggtacggctc
    12541 ttttttagac tatatcccat agcctttaga gcgtaatgaa tagttgttgg aggacagttg
    12601 aattcagcag ctatttcagt caaataagca tcgggatgag tttcaatata gatttttaat
    12661 ttatctctat caattttttc aattaatagt ggaagttttc ttgaagttag tgtattgaaa
    12721 cgtttttata cagtgctaaa atttgaagtg tagtgcagat ggatttgtaa tagtattata
    12781 gcaattcttt ggagaaggtc gagacaagat aaaataggta tctttgagat ataagcatga
    12841 tttactataa aattattgag ttattcataa aaatttctct atcaaatatc ataatgcgtc
    12901 gtttaaggag atggttacaa tgcaatatag ttgtggaaaa ataaatatta atatccctga
    12961 tggatatgga gacattaagg atatagtgtt ttcggctcat attatagtta ggtataataa
    13021 tggacattgt ggaggtatag atccgcatat aattggactt tgtaaaaagc agatcagaag
    13081 gatgtctcta tatcctattt tgataatcgt atctagagat tcaaaggtta ttgatgatta
    13141 taaaaattta gatattgcct atgttgattg tactcaatgt tcaaataatt ttgaaactgc
    13201 cttacacgtt aaaaatattt taaaattatt aaaaatccaa cttatacact gtcatggcta
    13261 ctcaactaat tattttttat atatgttaaa aaaacttgac aagaatggat ttggaaaggt
    13321 taagacagtg ataacatgcc atggatgggt tgaatataac ttaaaaaaga aattcttgac
    13381 ttattttgat ttttggacat attctatggg agatgctttt atttgtgtat ctgaaactat
    13441 gaaaaaaaga ttggagagta taataaaaaa ataagaagat agttgcaata aataacggaa
    13501 ttaatgtatc aaatagcgat ttagatgtag taggtgttca agactttaaa aaagaatttt
    13561 gtattccaaa taacaaaaaa atcatttgtt atgttggaag gttggatcca gaaaaaaggc
    13621 cggatagatt ccttgaattt gcagaaaaat tatttttagt cagagaagat gtgattttta
    13681 ttatggctgg aaatggtagt atgtgggctg ctttgaaaga aaaaatttgc catttgaaat
    13741 gtagagataa tttcaggtta cttggtgaaa tctatccagc tactatagtt taccaaatat
    13801 cggatttatt gtatatttct tctgatacag aaggaatacc tatgtgtgtt ttagagtcaa
    13861 tgtcacaagg aacttcggtt ttagctagta atgttggcgg gttaagtgaa attattgaac
    13921 atagggttga tggattttta tttgagaagg aagatgttga gggagtgtgt gcttgtgcta
    13981 attttttact caatgattct gagtatttga aatatatagg tgagaatagt aaatcaaaaa
    14041 taagaaaaca tttttctgtg caaaaaatgt ttgtagaaac catgagagta tatgatgaat
    14101 tattagagaa gagtagtcat ggataggaat atagatcaag aattagtaag tattataata
    14161 ccaacacata ataggtatga atctctgatt agagctgtga aaacttgttt acatcaaagt
    14221 tataaaaata tcgaagttat aattattgat gataattata gtaatgtaaa tttaagaaat
    14281 aaaattatcc atcaatttgg ctataccaat catagaatta agttaatttt aagtaatgaa
    14341 gatttaggtg caactaatgc cagaaacata ggtatcaaaa attctagagg taagtatata
    14401 tcatttttag acgatgatga tgaatatatg ccagatcgaa ttttaaagtt gatggcttgt
    14461 tttaaaaaga gtagaatgaa gaatttagct ttagtttata gttatggaat aataatttat
    14521 ccaaatggta cacgagaaga ggagaagacc gattttgttg gaaatccctt gtttgttcaa
    14581 atggttcaca tcaggacggt gttgttttat taaaactact tgctcaagga taccaaattg
    14641 atatagtgcg agaattcttg gtgaattact acgctcacag taaagaaaac ggtatcactg
    14701 gagtgacaca aaaaacaatt aatgcagatg aagaatatta taattactgt aggaaatatt
    14761 ttaatttatt gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca
    14821 taaagcggtt actattaata ggagacaaat gcaaggcttt aaaagtaatc aagaaggcaa
    14881 gagaagaaaa aatttttaac gaatttcttt tttgaaatat atgttattat atcattttgg
    14941 ttttttctat tgtatatatg acaactatgt tcaattaaaa tttagaaagt gagaaactat
    15001 tgtgtatact attataaaat caaatataaa aaaatttagt ttattaacga tatttattgt
    15061 tgctggtcaa ttattgctaa tttatgcagc aactattaat gctctggtgt tgaatgaatt
    15121 aattgcgatg aatttagagc ggtttttgaa attgtcaatc taccaaatga ttgtctggtg
    15181 tgggataata ttccttgact gggtagtgaa aaattatcag gttgaagtga tccaagagtt
    15241 taatctagag attcgaaata gaattgccac agacatctct aactctacct atcaagaatt
    15301 tcatagtaaa tcatcaggaa catatctttc gtggctaaat aatgatgttc agactttaaa
    15361 tgatcaggct tttaaacaac tttttttagt aataaaagga atttctggta ctatatttgc
    15421 agttgtgact cttaatcact atcattggtc attgactgta gccaccttgt tttcattaat
    15481 gattatgcta cttgtaccaa aaatctttgc atcgaaaatg cgagaagtta gtctaaattt
    15541 aactaaccaa aatgaagctt ttttaaaatc tagtgagact atattgaatg gatttgatgt
    15601 gttagcgtcc ttgaatcttt tatatgtatt gcctaagaaa attaaagaag caggaatttt
    15661 attaaagatg gttatacaaa gaaagacaac tgtagaaacg ttagcaggcg ctattagctt
    15721 ctttctcaat attttttttc agatatctct cgttttttta acaggctatc ttgcaataaa
    15781 aggaatagtg aaaattggta ctattgaagc aataggagca ctaacaggtg ttatttttac
    15841 agcgctaggt gaattaggag gtcaattatc ctctattatt ggtacgaagc ctattttttt
    15901 aaaattgtat tcaattaatc caattgagtc aaataaaatg aatgatatcg aaccaaatga
    15961 ggtgaataga gattttccgt tatatgaagc aaaaaatatt tgctataagt atggagataa
    16021 agaaatatta aaaaacttaa atttttgttt tcaacgtaat gaaaagtatt taattttagg
    16081 tgaaagtgga agcgggaaat ctacattatt aaaattattg aatggctttt tgagagatta
    16141 tagtggagaa ttgcgattct gcggggatga tataaaaaaa acctcctatt taaatatggt
    16201 ttcgaatgtt ctatatgtag atcaaaaagc ttatttgttt gaaggtacga ttagagataa
    16261 tattttattg gaagaaaatt atactgatga agaaatacta cagtctttag agcaagttgg
    16321 tttgagtgta aaagattttc ctaataacat tttagattat tatgttggtg atgatgggag
    16381 attactgtca ggagggcaga aacaaaaaat tactttagct agagggctaa ttagaaataa
    16441 gaaaatagta ttaattgacg agggaacttc tgctatcgat aggagaactt cgttagcgat
    16501 tgaacgtaag atattagata gagaggattt gactgtcatt attgttaccc atgctccgca
    16561 tccggaactt aaacaatatt ttactaagat atatcaattt ccaaaggatt ttatttaaga
    16621 atatagggga gggaaacatg agattctatt gtgaagctta tgaggtaatt actgaagaga
    16681 aaaaagtata ctttaatgat attgagttag aagttaagta ttcctctgtc gaagaattgt
    16741 ttataatatg tgagaaatta ttagataaga aaaaagtatc atttttttat gtagatgaga
    16801 aacccttaag gtatctgtta tttgactata tatttccact agttctagct aaaaaaaaat
    16861 atcccaatct tagatggagt ttccaataag caagttgctc caacgttgct gcatcacttt
    16921 tctttggaaa ttgaaaagaa ttttatcgat ttttgctata aaaatatgga tctcatccta
    16981 aaaactcaaa gtatatcttt gtgtcataga gaagagctta ttattgtaga tgtttcagat
    17041 gactctaaat ttggtgtttt ttacaagcgt tttagaacac tggttgataa aaataacgga
    17101 aaatatgttt gtgtttataa tttcagtcgt gtttcagata tactgcaaaa ctggaaaaat
    17161 tattgcaatc gaaaattttc ggttacgttt actgaaagcc aatttgaatt atttaagctt
    17221 ttatataatc aaaaaaattt taaaacaatt tcgttgctat ttggaaaaaa attgttgctg
    17281 gaggaattat ctattatagc gatcttacta atatagaata cttttgtatt ttttggtggg
    17341 atagtatgtt tgggaaagat tctattggaa aatacgtata tgtagaagag attagtagat
    17401 gtcatttttt agatagaaat tattc
//
LOCUS       DAVIME010000048        16531 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVIME010000048 DAVIME010000000
VERSION     DAVIME010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16531
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.048"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            142..1920
                     /locus_tag="VV588_001699"
     CDS             142..1920
                     /locus_tag="VV588_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU7083999.1"
                     /translation="MSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIY
                     WNKKTNKYKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIG
                     RSAMVTKLLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYP
                     ELEPSKLGTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGK
                     TYLAKEIAKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKD
                     FCQKAKETQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSG
                     VPGWSLPSKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKF
                     VFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIG
                     TMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIEN
                     VQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAF
                     ELTNNEQKDQAVADDNEGDENDDADY"
     gene            1907..3223
                     /locus_tag="VV588_001700"
     CDS             1907..3223
                     /locus_tag="VV588_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU7084000.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            3398..4384
                     /locus_tag="VV588_001701"
     CDS             3398..4384
                     /locus_tag="VV588_001701"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU7084001.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVSQLKADTPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            4448..4519
                     /locus_tag="VV588_001702"
     tRNA            4448..4519
                     /locus_tag="VV588_001702"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4481..4483,aa:Arg,seq:ccg)
     gene            4702..5400
                     /locus_tag="VV588_001703"
     CDS             4702..5400
                     /locus_tag="VV588_001703"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU7084002.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            5391..8930
                     /gene="smc"
                     /locus_tag="VV588_001704"
     CDS             5391..8930
                     /gene="smc"
                     /locus_tag="VV588_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU7084003.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENACKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIVIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            8927..9721
                     /locus_tag="VV588_001705"
     CDS             8927..9721
                     /locus_tag="VV588_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU7084004.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            9721..10539
                     /locus_tag="VV588_001706"
     CDS             9721..10539
                     /locus_tag="VV588_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU7084005.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVSEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            10543..11820
                     /gene="ftsY"
                     /locus_tag="VV588_001707"
     CDS             10543..11820
                     /gene="ftsY"
                     /locus_tag="VV588_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU7084006.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(11864..13351)
                     /locus_tag="VV588_001708"
     CDS             complement(11864..13351)
                     /locus_tag="VV588_001708"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU7084007.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(13500..14240)
                     /locus_tag="VV588_001709"
     CDS             complement(13500..14240)
                     /locus_tag="VV588_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU7084008.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(14240..16405)
                     /locus_tag="VV588_001710"
     CDS             complement(14240..16405)
                     /locus_tag="VV588_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU7084009.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT         5168 a         2940 c         3651 g         4772 t
ORIGIN      
        1 aaagttagtt tagaagattt ttataaatgg tatagtctaa ataaagaaga gttattaaat
       61 aaggcaactg ttggtgaaaa gtttaatgat aaattaaaag aagagtttct ccaggaatgg
      121 cctttggata ggattttaac aatgtcaatc gatgaatatg taataggaaa gggacagcaa
      181 aataagtctt tatgctacgc tcttgagaag ggaaaataca aaaatctatt tcttggaatt
      241 tctggtggct cagcttcaaa atttggtatt tattggaata aaaaaacaaa caaatataaa
      301 gatcaagcta ataatgagat ttcagagttg gatcagcgat tttcaaaatt aaaatcagat
      361 ttgtatgaaa ttatcaaaga aggtattcgt tttaactttg aaaatcctat ttttgatatg
      421 aaaagatcaa caaatgaatt tattggtcgt tctgctatgg tgacaaaatt actttgtatc
      481 tatactgagg gagatccttt ctttggtgta aatattaata gtcagaaaga attttggaac
      541 cactttgttt ctcagacaaa tcaaggtgga ccttatctgc aaaatcataa aataattgaa
      601 ctggtgtcca aaacttatcc tgagttggag ccatcgaaat taggaactat gctttttgag
      661 tattctaagc tttttatgga aaataaggaa gacaatagta caatggattc atcaaacaat
      721 tttagtcatc aattaactca atctctatta aagtctccaa accttatcct tcgtggtgct
      781 cctggcacag gaaagactta tcttgctaaa gaaattgcca aagaattaac ggatggcaac
      841 gaagaccaaa tcggatttgt acaatttcac ccatcctatg attatacgga ttttgtagaa
      901 ggtttaagac cagtatcaaa tggggatgga gctattgagt ttaggctaca ggacggtatt
      961 tttaaagatt tttgtcagaa agcaaaagaa acccaattga ttggaggaca agataatttt
     1021 gatgaggctt gggattctta cttagaatat ataaatgttg ctgaagaaaa agaatatata
     1081 acaaaaacat cttacttatc tgttaatagt agacaaaatt tgtcagtaaa ttatgatagt
     1141 ggtgttccag gatggtcact acctagcaaa tatgtttacg agttgtataa agataaaaat
     1201 tataataagc aagaatacta caaaagtggt ggaaaaactg tcctagaaac attgagaaag
     1261 agatttggtt tgaaagacta tgtttcccca acagaaattg atactgataa gaaattcgtc
     1321 ttcatcatcg atgaaatcaa tcgtggggag atttctaaga tttttggcga actctttttc
     1381 tctatcgacc ctggctatcg tggtgaaaaa ggaagtgttt ctacccaata tgcaaatcta
     1441 cacgaaactg atgaaaagtt ctatatcccc gaaaatgttt acatcatcgg aactatgaat
     1501 gatattgatc gttcagtgga tacctttgat tttgctatgc gtcgtcgttt tcgttttgtt
     1561 gaagttactg ccgagggtca agttggcatg ttggataaag agctgaatat ccatgcagaa
     1621 gaagcaaaaa ttcgtctaag aaacttgaac gctgctatcg aaaatgttca ggaattaaac
     1681 agtcattatc atattggacc aagttatttt cttaagttga aggatgtaga ttttgactat
     1741 gaattactct ggtctgatta tattaagcct ctcctagaag actacttgcg aggttcttat
     1801 gatgaggttg aaactttgga aactttgaaa aaagcatttg aactgacaaa taatgagcaa
     1861 aaagatcagg cagtagctga tgacaatgaa ggcgatgaaa acgatgatgc ggattactga
     1921 taatcaacac aagattatta aagaaaaatt tgttgaagaa tatcctaaac taagcaatct
     1981 tcttttagac agaaccttgg aaagtctatc ccaagatgaa cgtattttca tttttccaaa
     2041 tgatttgact catactcctg atttggataa ggaccaaaag atttttgaaa cagtcaatca
     2101 gaaaatcaag acagggaacg tgattggttt tcttggatat ggtcaggaaa gattaacgat
     2161 ttcctcacga ttttctgatg agagtaatga ccattttttg cattatctct taaacaaggt
     2221 tcttcatatc aatctcacta gtttagatgt tgctttgtct cgtgaagaga ggctttatca
     2281 acttttgatg tatctcttcc ccaagtatct acaagctgct attcgaaaag gtctttataa
     2341 ggaataccag agattttctc ataacgacag tcatgttaag ggagtgattg atgtaagaaa
     2401 ccatctcaag aaaaatcttc ctttcacggg aaatattgcc tacgcaacga gagagttcac
     2461 ctatgataat cccctcatgc agttggtccg tcacactatt gaatacatta agaatcagaa
     2521 aagcattggt caaggggtac tagataatct ctcaactagt cgtgaaaacg tatctgaaat
     2581 cgtgcgtgta acgccctctt ataaactagc tgatcgtgct aagattattc ggggaaatca
     2641 atctaaacct atacgtcatg catactttca cgagtacaga aacttacaag aactttgtct
     2701 gatgatccta aaccaagaaa agcacggttt agggtatcaa gatcaaaaaa tctatggtat
     2761 tctctttgat gttgcctggc tttgggaaga gtatgtttac accttgttgc caaaaggttt
     2821 tgtacatccc agaaataagg ataagacgga tggaatttca gtattttctg ttgggaaacg
     2881 aaaagtatat ccagattttt atgacagaga acgaaagatt gttctagatg caaaatataa
     2941 aaaactggaa ttgactgaaa aaggaatcaa ccgtgaggac ttattccagc tgatttccta
     3001 ttcttatatt ttaaaagctg agaaggctgg actgattttt cctagtatgg agcagtcagt
     3061 aaatagtgaa ataggaaaag tagctggcta tggagctcaa ttgaagaagt ggtctattcg
     3121 aatccctcag aatgcctcat tctatagtac attttgtaaa atgatggaaa attcagaaga
     3181 aaattttaaa gcgattattg atgaagaagt ggggagaaaa taatttcccc tctttctttt
     3241 atttttaaca caagtaaaac ccgaacgata tattttaatt cataaaataa tttgacaaaa
     3301 actgtacttt gatttataat aaattaagga aacgtcggaa aaggcgtagt gatgcaagag
     3361 cataggtagg tcattacaaa agaaacgaga catcgatatg ttaaatgaat ttccaatttt
     3421 tgattacgaa gatattcaat tgattccaaa taaatgtgtc attaaaagcc gtgcagaagc
     3481 ggatacaagt gtcactttag gaaatcacac ctttaaacta cctgttgtgc cagcgaatat
     3541 gcagacgatt ttggatgaaa atgtagcaga gcaactggct aaaggtggtt acttctacat
     3601 tatgcaccgt tttgatgagg caggacgcat tccttttatt aaacgaatgc acaatcaagg
     3661 gctcattgct tctatctctg tcggtgttaa ggattatgag tatgattttg ttagccagct
     3721 caaggctgat actcctgagt atatcactat tgatattgct catggtcatg cggatagcgt
     3781 gatttctatg attcaacaca tcaagaaaga attgccagat acctttgtca ttgctggaaa
     3841 tgtgggaaca ccagaagctg tgcgtgaatt ggaaaatgct ggtgcggatg ctactaaggt
     3901 cggaatcggt cctggtaagg tttgtatcac caaggttaag actggttttg gtacaggtgg
     3961 ttggcagttg gctgctctac gctggtgtgc caaggctgcg cgtaaaccga ttatcgctga
     4021 tggaggaatt cgtactcacg gtgatattgc caagtctatc cgcttcggtg ctagcatgat
     4081 catgattggt tccctctttg caggacacat tgaaagtcca gggaaaacga ttgaagtcga
     4141 tggtgaacag ttcaaagaat attatggttc agcctcacaa tatcaaaaag gtgcttacaa
     4201 aaatgtggaa ggcaaacgta tcttgcttcc tgctaaaggt catctgcaag acactttaac
     4261 tgagatggaa caagaccttc aaagtgctat ttcttatgca ggtggacgtc aggttgctga
     4321 ccttaaacac gttgattatg tgatcgtgaa aaactccatc tggaatgggg atgcttccca
     4381 ctaagacggg gtctttgacc aaaaaacttg ttattagagc aaatttctgt tataataaaa
     4441 caagtttcca cccttagtgt aatggatatc acgtaagatt ccggttcttg agatgggggt
     4501 tcgattccct cagggtggat gtaaacatcc taaaaagcct ttaatagggc ttttttcttt
     4561 atcctgaccc aaatttgccg ctaaaactga gaatctctgt ctaaagaatt cccaaatgct
     4621 ttccagtccc gttttagagt gactcagggg gctttttttg atataataaa aaggactatt
     4681 atcagttaga aagaggttgg tatgaaagaa ttacaaactg tactaaagaa tcattttgca
     4741 atcgaatttg cagacaaaaa tttactggaa actgccttta ctcatacgag ttatgccaat
     4801 gagcaccgcc tcttaaaaat ttcacacaat gaacgcttgg aatttttagg agacgctgtt
     4861 ctacagttat tgatttcaga atatctatat aaaaaatatc ctaaaaagcc tgaaggtgac
     4921 ctatcaaaac tccgtgctat gattgtccgt gaggagagtt tagctggttt tgcgcgtgat
     4981 tgccagtttg accagtttat caagttgggt aaaggggaag aaaaatctgg tggtcgcaat
     5041 cgtgacacca ttcttggtga tgcctttgaa gcctttcttg gtgcccttct tttggataag
     5101 gatgtggcca aggtcaagga atttatctat caagtcatga ttcctaaggt tgaagcaggc
     5161 gaatttgaga tgattacaga ctataaaacc catctccaag agttacttca ggtcaatggt
     5221 gatgtggcta ttcgttatca ggtgatttct gaaacagggc ctgctcacga taaggtcttt
     5281 gatgtagaag ttcttgttga aggtaagagc atcggtcaag gccaaggtcg ttctaagaaa
     5341 ttagcagagc aggaagctgc caaaaatgcc gttgagaagg ggctggattc atgtatttaa
     5401 aggaaatcga aattcagggg ttcaagtctt ttgctgataa gaccaaggtc gtttttgacc
     5461 aaggtgtgac ggcagttgtt ggacccaatg gatctggaaa gtccaatatt acagaaagtc
     5521 tgcgttgggc tttgggggag tctagtgtca agagtctccg tgggggcaag atgccggatg
     5581 tcatctttgc tggaaccgaa agtcgcaaac cgctcaatta tgcttctgta gttgtgactc
     5641 tggataatca tgacggattt atcaaggatg caggtcaaga aatcagggtg gaacgccata
     5701 tctatcgtag tggagatagc gaatacaaga ttgacggcaa gaaagtccgt ctgcgtgata
     5761 ttcatgacct cttcttggat actggattgg gacgagattc cttctctatt atttcccaag
     5821 ggaaggttga ggagattttt aattccaagc ctgaggaacg acgagctatt tttgaagaag
     5881 ctgcaggagt tttaaaatac aagactcgca gaaaagaaac tgagagtaaa ctgcaacaaa
     5941 ctcaggataa tctagaccgc ttagaggaca ttatctacga gttggataat caaatcaagc
     6001 ctcttgagaa gcaagctgag aatgcctgta agtttttaga cttggaagga caacgtaagg
     6061 ctatttattt agacgttctg gttgctcaaa tcaaggaaaa taaggcagaa ctagagtcga
     6121 cagaagaaga gctggctcag gttcaagaac tcttgatgag ttattaccaa aagcgtgaaa
     6181 aattagaaga agaaaatcaa actcttaaaa agcaacgcca agatttacag gctgaaatgg
     6241 ccaaagacca aggcagtttg atggacttga ctagtctgat tagtgattta gaaagaaaat
     6301 tagccctatc gaaactggag tccgagcaag tggccttgaa tcaacaggag gcacaagctc
     6361 gtttggctgc tttggaggat aagagaaatt cactcagcaa agaaaagtct gataaagaaa
     6421 gctctttagc tctgttagag ggaaatctag tccaaaataa tcaaaaactc aatcgtttag
     6481 aagctgaatt gctggctttc tcagacgatc ctgatcagat gattgagctc ttacgtgaac
     6541 gctttgtagc tcttttacaa gaagaagcgg atgtctcaaa ccagttgacc cgtattgaga
     6601 atgagttgga aaatagtcgt cagctttctc aaaaacaagc agatcaacta gaaaagctga
     6661 aagagcaatt agctatagct aaagagaagg ctagtcagca aaaggaagag cttgaaactg
     6721 ccaaggagca ggttcagaaa ttattggctg actaccaagc tattgccaag gagcaagagg
     6781 agcagaaaac ttcctatcaa gctcaacaaa gccaactctt tgaccgtctg gataatctca
     6841 aaaacaagca ggccagagct caaagtttgg aaaatatcct gagaaatcat agtaactttt
     6901 atgcaggtgt taagagtgtt ctccaagaaa aagatcgcct aggtgggatt attggtgcag
     6961 tcagtgagca tctgaccttt gatatgcatt atcaaactgc cctagaaatt gcgcttggag
     7021 cgagtagtca gcacattatt gtagaagatg agaatgcggc aaccaaggct attgacttcc
     7081 ttaaacggaa cagagccggt cgtgcaacct ttcttccttt gaccactatt aaggcgcgta
     7141 cgatttctag tcagaaccaa gatgctatcg ctgtaagccc aggtttcctt gggatggcag
     7201 atgagttggt gacttttgat actagactgg aagccatttt caagaacttg ctagctacga
     7261 cggctatctt tgataccgta gaacatgcgc gtgaagctgc tcgacaagtt cgttatcagg
     7321 ttcgtatggt gacattggat gggacagaat tacgcacggg tggttcctat gcgggtggtg
     7381 ccaatcgcca aaataacagt attgtcatca agccagaact ggagcaatta caaaaagaaa
     7441 ttgctgcaga tgaagcaagc ttgggttcag aagaagcggc tttgaagacc ttgcaagacc
     7501 agatggctgc attgacagaa agattagaag ccatcaaatc tcaaggagag caggcacgta
     7561 ttcaggagca aggcttgtcc ctcgcttatc agcaaactag tcagcaagtt gaagaactgg
     7621 aaactctttg gaaactccaa gaagaggaaa tagatcgtct ttctgaggga gattggcaag
     7681 cggataagga aaaatgtcaa gagagccttg ctactatcgc cagtgaaaag caaaatctgg
     7741 aagctgagat tgaagaaatt aagtctaata aaaacgccat ccaagaacgc tatcaaaatt
     7801 tgcaggaaga ggtggcgcaa gctcgcttgc ttaagacaga actgcaaggg caaaaacgtt
     7861 atgaagtagc tgatattgag cgtttaggca aggaattgga caatcttaat atcgaacaag
     7921 aagaaattca gcgcatgctc caagaaaaag ttgacaatct tgagaaggtt gatacagaat
     7981 tgctcagtca acaggcggaa gaatccaaaa ctcagaaaac aaatctccaa caaggtttga
     8041 ttcgcaagca gtttgagttg gatgatatag aaggtcaact ggatgatatt gccagtcact
     8101 tggatcaagc tcgccagcag aatgaggagt ggattcgcaa gcaaacacgt gctgaagcca
     8161 agaaagaaaa ggtcagcgag cgcttgcgcc atctacaaaa tcaattaaca gaccagtacc
     8221 agattagcta tactgaagca ctagaaaagg cacatgaatt ggaaaacctc aatctggcag
     8281 agcaagaggt gcaggattta gagaaggcta ttcgctcatt gggacctgtc aacttggaag
     8341 ctattgacca gtacgaagaa gttcacaacc gtctggactt tctaaatagt cagcgagatg
     8401 atattttgtc agcgaaaaat ctgctccttg aaaccattac agagatgaat gatgaggtca
     8461 aggaacgctt taaatcaacc tttgaagcta ttcgtgagtc ctttaaagtg accttcaagc
     8521 agatgtttgg cggaggtcag gcagacttga tattgactga gggcgacctt ttaacagctg
     8581 gtgtggagat ttctgttcaa cctccaggta agaaaatcca gtcgcttaac ctcatgagtg
     8641 gtggtgaaaa agctctatcg gctcttgcct tgcttttctc cattattcgt gtcaagacca
     8701 ttccttttgt catcttggat gaggtggaag ctgcgctgga tgaagccaat gttaaacgtt
     8761 ttggggatta cctcaaccgc tttgacaagg acagccagtt tatcgttgta acccaccgta
     8821 agggaaccat ggcagcggct gattccatct atggagtgac catgcaagaa tcgggtgttt
     8881 caaagattgt ttcagttaag ttaaaagatt tagaaagtat tgaaggatga caattaaact
     8941 agtagcaacg gatatggacg gaaccttcct agatgggaat ggacgctttg atatggatcg
     9001 tctcaagtct ctcttggctt cctacaagga aaaagggatt tactttgcgg tggcttcggg
     9061 tcggggattt ctgtctctgg aaaaattatt tgctgatgtt cgtgatgaca ttattttcat
     9121 cgcggaaaat ggcagtttgg tagagtatca aggtcaggac ttgtatgaag cgactatgtc
     9181 tcgtgacttt tatctggcaa cttttgaaaa gctgaaaacg tcaccttatg tagatatcaa
     9241 taaactgctc ttgacgggta agaagggttc atatgttcta gatacggttg atgagaccta
     9301 tttgaaagtg agtcagcatt ataatgaaaa tatccaaaaa gtagcgagtt tggaagatat
     9361 cacagatgac attttcaaat ttacaaccaa cttcacagaa gaaacgctag aagctggtga
     9421 agcttgggtt aatgaacatg tccctggtgt taaggccatg acaactggct ttgaatctat
     9481 tgatattgtt ctggactatg tcgataaggg tgtagctatt gttgaattag ctaaaaaact
     9541 tggtatcaca atggatcagg tcatggcttt tggagacaat cttaatgact tacatatgat
     9601 gcaggttgtg ggacatcctg tagctcctga aaatgcacga cctgaaattt tagaattagc
     9661 aaagactgtg attggtcacc ataaggaacg gtcggttata gcttatatgg agggcttata
     9721 atggcagata taaaattgat tgcattggac ttggacggga ccttgctgac tactgataaa
     9781 aggctgacgg atcgtaccaa ggaaaccttg aaagctgcgc gtgatcgtgg tatcaaggtc
     9841 gtattgacaa ctggtcgtcc cttaaaagcc atggacttct ttctccatga gttagggact
     9901 gacggccatg aagatgagta taccattact tttaatggtg gattagttca gaaaaataca
     9961 ggagaaatcc ttgataaaac agtcttttca tatgatgatg tggcacgttt gtatgaagaa
    10021 acagagaaat tatcactgcc tcttgatgcc atctcagaag gaacagttta tcaaatccaa
    10081 tcggaccaag aaagtcttta tgccaaattc aatccagctt tgacctttgt tccagtggac
    10141 tttgaagact tatctagtca aatgacctac aacaaatgcg tgactgcctt tgctcaagaa
    10201 cccttggatg cagccattca gaagatttct ccagaattgt ttgaccaata tgaaatcttt
    10261 aaatcacgtg aaatgttgct agaatggtca ccaaagaatg ttcataaagc aacaggtttg
    10321 gcaaaactaa tcagccatct tggaatcgac caaagtcaag tgatggcttg tggtgacgag
    10381 gccaatgacc tctctatgat tgaatgggca ggtcttggtg ttgctatgca aaacgctgtt
    10441 tctgaagtaa aggcagccgc aaatgtagtg acgccgatga ccaacgatga ggaagctgtc
    10501 gcctgggcta tcgaagaata tgtgctaaag gagaactaag atatgggatt gtttgaccgt
    10561 ctattcggaa aaaaagaaga acctaaaatc gaagaagttg taaaagaagc tctggaaaat
    10621 cttgatttgt ctgaagatgt tgatcctacc ttcacagaag ttgaggaagt ttctcaggaa
    10681 gaagcagagg ttgaaattgt tgaacaagct gtgttccaag aagaggaaat ccaagacaca
    10741 gttgaagaaa gtctggattt agagccagtt gtagaagttt ctcaaaaaga agtcgaagaa
    10801 tttccacact cagaagaagg gaatactgag tttctagaga ctatagaaga aaataattct
    10861 gaagttcttg aagcagaaag gcctcaagca gaagaaaccg ttcaggaaaa atatgaccgc
    10921 agtcttaaga aaactcgtac aggtttcggt gcccgcttga atgccttctt tgctaacttc
    10981 cgctctgttg acgaagaatt tttcgaggaa ctggaagaac tgctgattat gagtgatgtt
    11041 ggtgtccaag tcgcttctaa cttaacggag gaactacgtt acgaagccaa gcttgaaaat
    11101 gccaagaaac ctgatgcact tcgtcgtgtc atcattgaga aattggttga gctttatgaa
    11161 aaggatggta gctacgatga aagcatccac ttccaagata acttgacagt tatgctcttt
    11221 gttggtgtga atggtgttgg gaaaacaact tctatcggaa aactagccca ccgctacaaa
    11281 cgagctggta agaaggtcat gctggttgca gcagatacct tccgtgcggg tgcagtagct
    11341 cagctagctg aatggggccg acgagtagat gttccagtag taactggacc tgaaaaagct
    11401 gatccagcca gcgtggtctt tgatggtatg gaacgtgccg tggctgaagg tatcgatatt
    11461 ctcatgattg atactgctgg tcgtctgcaa aataaggata accttatggc tgagttggaa
    11521 aagattggtc gtattatcaa acgtgttgtg ccagaagcac cacatgaaac cttcttggca
    11581 cttgatgcat caacaggtca aaatgcccta gtacaggcca aagaattttc gaaaatcaca
    11641 cctttaacgg gaattgtttt gactaagatt gatggaactg ctcgaggagg tgtggttcta
    11701 gccattcgtg aagaactcaa tattcctgta aaattgattg gttttggtga aaaaatcgat
    11761 gatattggag agtttaactc agaaaacttt atgaaaggtc tcttggaagg cttaatctaa
    11821 tcagaagcaa aaatcctgca aggtacaaac ttgcaggatt tttttattcg aaacgaccat
    11881 cttgacgata ggcgatatct ggttgccaag tccatttggc atcgaatttt tcaagtaggt
    11941 caaagctggc ttgaggtccc atgcttccag ctttatagtc atgaagtggg gcaccatttt
    12001 cggcccagag ctcttcaata cggtcaatca acttccatga cgcaccaact tcatcccagt
    12061 ggctaaagtt agttgagttg ttatttagga catcataaat caatttttcg tatggttctg
    12121 gagaagcacc agttgcagtc gcatctgtac ggtaatcaag tgagttagga gccaagttaa
    12181 attcttctcc tacttgcttc ccatttaggc taagagagaa gccttctgtt ggttgaatat
    12241 agatggtcaa aatatttgga gcaagtggtt ctccaaagat agaatccatt tgtttaaaga
    12301 cgatgttgac atgggttcct ttttcagtca gtcgtttacc tgtacggaaa aagaaaggaa
    12361 caccacggaa tcgatcgctg tctacaaaga aggcacctga tgtaaaggtt tcagttgttg
    12421 attctggatt cacatttggc tcgctacgat aagagatgta tttcatgcca tcaatcttac
    12481 cagagcggta ttgcccacgg ataaagtgtt ctttgagttc ttcatcagtt ggatgataga
    12541 ggtttttaaa gaccttaatc ttttcagcac gaatctcgtc ttttgtgaag cttgctggtt
    12601 tgtccatggc gaggagcgaa agaagttgta gagtgtggtt ttggaccatg tcacggaggg
    12661 caccggattg gtcatagtag ccaccacgtt cttctacacc caagcgctcc gcaaaggtaa
    12721 tttgaacatt gtcgataaaa tccttgttcc aaacgttttc aaaaatcaag tttgcaaagc
    12781 gaactgcaaa gatgctttgg atcatttcct taccaagata atggtcgata cggaaaattt
    12841 gttcttcgtc aaatgttgct aggagttcgt cattcaactt gtttgcagtt gcgtaatctg
    12901 taccaaatgg tttttcaacg atcaagcgct caaaaccttt gccatcgaca atgttttcag
    12961 atttgaggtg tttggcaatg gttccaaaga actgaggtgc catagacaag aagaagagct
    13021 tattgtgttc agcttggtat ttttcattaa gctcagcttg taattgacgc aaagcaatat
    13081 aatgttccga atcattgaca tcatggcttt gatagtagaa gtggctagca aattcttggg
    13141 cttgctcggt actatctgcc aaatcaagga tggactcgac aactacagat tcaaaatatt
    13201 ccttactcca aggtctacgg gcagttccaa taacggcaaa gtgcttggaa agattgccgg
    13261 atttatatag tctaaaaagg gaagggtaga gcttgcgttt agccaggtct ccactcgcac
    13321 cgaaaattgt aacaataacc ttagatgaca tctagctacc taatttctat ttttattcct
    13381 agtcttgcta ggtatgagga aacctcattt cataaactta attctaacat aattttccga
    13441 aaaatcaaaa attccaatac gaggtagaaa aactgcaagg aaatccttac agtttgagtt
    13501 tagacgttta agaccttatc taagaactct ttcagacgag ggtgttgtgg gttatcaaag
    13561 atttggtcag gtgttccgtc ttcaaggaac tcgccatctg cagtaaagat aacgcggttg
    13621 gcaacctgac gagcaaatcc catctcatgg gttacgataa tcatggtcat gccttgctca
    13681 gccaattcct tcataacgtt aagtacgtct ccaaccatct cagggtcaag ggcagaagtt
    13741 ggttcatcga agagcatgat gtctggattc attgctaggc cacgagcgat ggccacacgt
    13801 tgtttttgac cacctgatag gctatctgga ttggcattag ctttatctgc tagtccaacc
    13861 ttttcaagca actccattcc caattcctca gcttcttcct tagtcatcaa cttgtgctca
    13921 ataggagcaa aggtgatgtt gtccaataca gacatatgag ggaagaggtt gaagtgttgg
    13981 aataccatgc cgatattttc acggacgtgg tcaacattgg ttgttttttc agttaaatca
    14041 tagccgttca cagtgatgtg accgctagtg acttcttcta aaagattgag gctacggagg
    14101 aaagttgact taccagaacc tgaaggaccg atgatacaaa caacatctcc ttcatagaac
    14161 ttagtcgtaa ttccttttag gacttcattt tttccatagt gcttgtgtaa atcatttaca
    14221 tcaattttta attttgccat taacgaatcc tcttttctaa gcgtttcgct agtctagtca
    14281 aaagtgtgat aattacaaga tagaagatag caaggattgc atacatcttg aaactttggt
    14341 agttacgagc aatgataatc ttaccagttt ggaagagttc aaccaaaccg atagcagata
    14401 cgatagttgt atctttaaga gcgataacga attggttgac aaagtttggc aacatcaatt
    14461 tagttgcttg tggcaagata atcttacgca tggtttttcc ataagagata cccaagcttc
    14521 ggctggcttc catttggcca actggaacgg cctgaatacc accacgaacg atttcagcga
    14581 tataagcagc cgcattgagt gagagggcaa tggttccagc tacaaagtcg ttaattgggc
    14641 tttgttggcc tgtgatagac tcgatgaagt ttggaattcc ccagaagatg aaggctgcaa
    14701 gaatcatcaa tggaatacca cgaataacgt caacgaaaat ctcagagatg acgcgaagag
    14761 atttgtatgg gctaacgcta aacataccga agataattcc gatgacaatg gcaatagcaa
    14821 atgagataag agctagagca agagtgatac caagaccgct aaggagttgt ttgtagttgt
    14881 tttgaagcaa gccccagagc gttgtttcgt caacagtact tgttgaagca gttgaagatt
    14941 cgctagctag gtatttgtca agaatctttt ggaattcacc gtttgcctta aggtttgcaa
    15001 gtccgttgtt gaacatttca atcagttctg gatttgctcc ttttttaacg gcaaaggctg
    15061 tttcaccgat tggagttcca gagattggag ttttcaattt ttgaccttgg ctgatagaat
    15121 atttgagaac aggttcatca tccataacgg catcaatggc accagtgttt aaactgtcat
    15181 acattgaaga accatcagca aaggttttga ttttgtaacc gtatttgctt tgattttctg
    15241 ttaggaaggt ttgagaagca gttccgtttt taacaccgac tgtctttcct tttagatctt
    15301 cataagaagc aatattgctt gattctttga caccaagaat ggtattagca gtgtagtatg
    15361 attctgagaa gtcaaaagtt gccttacgag catctgtgac agacatacca gcaatgatac
    15421 catcggcttg accagcttgg acagcactga tagcagcatc aaaaccaggg ttggtgattt
    15481 caatttcaaa accttggtct ttagcgattg ccttaatcaa ttccatatca ataccagtgt
    15541 attggttgct tgaattttgg aaaacaaaag gtgcaaaaga agaatcgctg gcaatgatat
    15601 atttagcctt aacaggaata gcttttaatc ctgcgagagt agttgtagtt ggcactgctg
    15661 aagatgatga agcagtccat ttcttgataa ttttatcaag actaccatct tttttcattt
    15721 cagccaaggc ttggttaaat tcagtaacca ggtgctcgta tttacttcct tttttcacac
    15781 cgaaagcaaa acttcctaca gcttcaccat ccatttcaat atggaggtct tgaccttggt
    15841 taatggcata ttcgataaca ggtttgtcat ccatcatggc atcgatggca ccagcactca
    15901 agctgttgtt cattaaatca ccagtgtcaa atgttttaat agtaaagccg tatttatctt
    15961 tgattgtttc aaggaaacgt tgagcggcag ttccgttttt aacaccaacg gttttgccag
    16021 ttaattggtc gtacttgcta attttgtgtg actttgtagt agcaatgaca acttttgtat
    16081 catagtaagt atcagacatg gtgaagactt tttcacgttc tttagtcttt gtcatccctg
    16141 ccatgatagc gtcggcttgc ccagcttgaa ccgcattgac cgctgcgtca aatccaggat
    16201 aggacatctg aatgttccag cctttaatct cagcgacttt gttaataatg tcaacatcaa
    16261 ttcctttata agtttgatct gaatctttaa actcaaaagg tgcataggcg gtatcagaaa
    16321 caatcttaat cgtttctgct ttggcaatac ctaatgagaa aattgggaat aaaattagca
    16381 aaaatgctag aaattttttc ttcattttta gtctcctttt ccgaatattc tctcattata
    16441 tcagaaaaag taaaaaaagg caaattttta tattttccgt gtcagaaaat ataacattga
    16501 tttttccttt tctttcttga attgctatta a
//
LOCUS       DAVIME010000049        16103 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVIME010000049 DAVIME010000000
VERSION     DAVIME010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16103
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.049"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(29..1651)
                     /gene="groL"
                     /locus_tag="VV588_001711"
     CDS             complement(29..1651)
                     /gene="groL"
                     /locus_tag="VV588_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU7084010.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1667..1951)
                     /gene="groES"
                     /locus_tag="VV588_001712"
     CDS             complement(1667..1951)
                     /gene="groES"
                     /locus_tag="VV588_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU7084011.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2221..2616)
                     /locus_tag="VV588_001713"
     CDS             complement(2221..2616)
                     /locus_tag="VV588_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU7084012.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2694..3455)
                     /locus_tag="VV588_001714"
     CDS             complement(2694..3455)
                     /locus_tag="VV588_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU7084013.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(3488..4114)
                     /locus_tag="VV588_001715"
     CDS             complement(3488..4114)
                     /locus_tag="VV588_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU7084014.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(4130..4447)
                     /locus_tag="VV588_001716"
     CDS             complement(4130..4447)
                     /locus_tag="VV588_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU7084015.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4444..4743)
                     /locus_tag="VV588_001717"
     CDS             complement(4444..4743)
                     /locus_tag="VV588_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU7084016.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5028..5219)
                     /locus_tag="VV588_001718"
     CDS             complement(5028..5219)
                     /locus_tag="VV588_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU7084017.1"
                     /translation="MSYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGAMIANDWVKDNGK"
     gene            complement(5380..6054)
                     /locus_tag="VV588_001719"
     CDS             complement(5380..6054)
                     /locus_tag="VV588_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084018.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLAIIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6060..6506)
                     /locus_tag="VV588_001720"
     CDS             complement(6060..6506)
                     /locus_tag="VV588_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7084019.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6620..7123)
                     /locus_tag="VV588_001721"
     CDS             complement(6620..7123)
                     /locus_tag="VV588_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU7084020.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVFIPATGFVILSLLRKKINAPRPYEEWDIKPLLDRDSPGQSM
                     PSRHVFSATIISMTCLHASLTVGFILLVLSALLGLVRVLGGVHYPKDVVVGYICGLAW
                     GVLFFLF"
     gene            complement(7120..7482)
                     /locus_tag="VV588_001722"
     CDS             complement(7120..7482)
                     /locus_tag="VV588_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEU7084021.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGEAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7608..9407)
                     /locus_tag="VV588_001723"
                     /pseudo
     CDS             complement(7608..9407)
                     /locus_tag="VV588_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9446..9895)
                     /locus_tag="VV588_001724"
                     /pseudo
     CDS             complement(9446..9895)
                     /locus_tag="VV588_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(10019..10735)
                     /locus_tag="VV588_001725"
     CDS             complement(10019..10735)
                     /locus_tag="VV588_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU7084022.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11616..13031)
                     /gene="ply"
                     /locus_tag="VV588_001726"
     CDS             complement(11616..13031)
                     /gene="ply"
                     /locus_tag="VV588_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU7084023.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13042..13374)
                     /locus_tag="VV588_001727"
     CDS             complement(13042..13374)
                     /locus_tag="VV588_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084024.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13445..14053)
                     /locus_tag="VV588_001728"
     CDS             complement(13445..14053)
                     /locus_tag="VV588_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084025.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14066..14524)
                     /locus_tag="VV588_001729"
     CDS             complement(14066..14524)
                     /locus_tag="VV588_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU7084026.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14649..15048
                     /locus_tag="VV588_001730"
                     /pseudo
     CDS             14649..15048
                     /locus_tag="VV588_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15812..16072)
                     /locus_tag="VV588_001731"
     CDS             complement(15812..16072)
                     /locus_tag="VV588_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084027.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAIISSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
BASE COUNT         4747 a         3668 c         2905 g         4783 t
ORIGIN      
        1 tttttataag ttgttttcta tagaaagctt acatcatccc gcccatcatg cttggatcca
       61 ttgctggagc tggggctact ggttctggtt tattggctac gactgcttct gttgtcaaaa
      121 tcaagctggc tacagatgct gcattttgta gggctgaacg actcacttta actggatcaa
      181 tgataccttg atcaatcatg ttaacccact cgccagttgc tgcgttgaat cctataccaa
      241 gctcagcatt tttcaaacga tcgataacga tagatccttc aaatcctgca ttgtgagcaa
      301 tttgacgaac aggttcttcc aaagcacgga gaacaatatt acgtcctgtt gcttcatctc
      361 ctgtcaattc caaggtagca acagctggaa tcacattggc aagagctgtt ccaccacctg
      421 caacaatacc ttcttcaaca gctgcacgag tagcgttgag ggcatcttca atgcggagtt
      481 tcatttcttt caactcagtt tcagttgcgg ctccgacctt aataaccgct acaccacctg
      541 acaatttggc caagcgttct tgcaattttt cacggtcaaa ttcagaagtt gtagtttcga
      601 tttgagactt gataaccgca acacggtgag aaatcgcttc aggatttcct gcaccttcta
      661 caataaccgt gctatctttg tccacggtca ctctcgctgc ttgaccaaga gcttcaattg
      721 tcgcatcttt caactcaaga ccaaggtctt ctgtgataac tgttccgcct gttaagatgg
      781 cgatatcttc aagcatagct ttgcgacggt caccaaaacc aggtgccttg actgctacta
      841 cgttgaaggt tccacgaatc ttgttcaaaa caagagttgg aagagcctcg ccatccacat
      901 catccgcaat aatcaagagt ggacgattgc tttggagaat gctttccaaa agtggcaaga
      961 tttcttggat attggaaatt ttcttgtctg taatcaaaat gtacggattt tcaaggtcag
     1021 ccaccatttt ttcgctatct gtcaccatgt actgtgaaag gtaaccacgg tcaaactgca
     1081 ttccttctac gacttcaagc tctgtttcca taccacgtga ctcttcgatg gtgatgacac
     1141 cgtctttgcc aactttttcc attgcttcag agatgtactc accaactttt tcagaacgag
     1201 aagatacggc tgcaacttga gcgatagctt ctttattggc aacagggatg gcgttgtttt
     1261 tcaaagcttc aactgctgcg gcaactgctg tttcaatccc acgacgaata ccgattggat
     1321 ttgcacctgc tgtgacgttt ttgattcctt cacggacgat agcttgggtc aagactgttg
     1381 cagtcgtagt tccgtcacct gcgatatcat tggttttaga agctacttct gatactaact
     1441 tagcacccat attttcaaaa tggtcttcca attcgatttc tttggcaatg gtcacaccgt
     1501 cattggtaat caagggtgaa ccgaatgact tttcaagaac gacattgcga ccttttggtc
     1561 ccaaggttac tttaacagtg tctgcaagga tatcgacacc acgaaccatg gctgaacggg
     1621 catctgatga aaatttaatt tcttttgaca tacttacttt ctccttctat tcctcaatga
     1681 ttgccaagat gttagcttcg cctacgatga tgtacttttc atcgccatct ttgacatcaa
     1741 gacctgcgtg ggcttcaact aagacacgat ctccagtttt aacacttgga gcaaccaagt
     1801 caccgttcaa ggtacgaaca ccttgtccag tagccacaac ttgagctgtt ttggtttttt
     1861 cttgggctga gcctgcaagg acaaagcccc caacggtttg ttctttttct tctattttta
     1921 agaccacacg gtcccctaat ggtttcaaca tctgatttcc tccataatga gatagatatt
     1981 attagcactc tttgaacttg agtgctaatt cataattcta ttgtatcact tggtcagaaa
     2041 tagtcaagaa aaaagtctga ctttctcaag ataaaaagcc tgagaccaac tcagactttt
     2101 taatgtttat actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca
     2161 aagcattgct ttgatgttgt ggataaagct aacgtggttt gaagagattt tcgaagagta
     2221 ttaaaatggc aattcttcct cttccaagac caaatctgcc aaatcttggc ctgcattatt
     2281 ttcacgcatg gcacgttgag cacgactttc taagagttgg aatcctgtca caaggacttc
     2341 ggttacatag ttcatctgac catttttctc aaagcgacgg gtacgcaatt ctccatcaac
     2401 ggaaatgaga ctacctttgg ttgcgtagct tgccaaagtt tctgctagcc tgccccatag
     2461 gaccatattg acaaaatcag cttcacgttc accgttttgg tctttgtaac gacggttgac
     2521 agcgatagtt gctcgcgcta ccgacttgtc attgttggtt ttgtgcaatt ctggtgtaga
     2581 cgttaaacgc ccaatcaaga taactttatt atacatattt tcttcctcct acttatctat
     2641 tcgtaggaaa tcaaaaaaag ttacagaaat ttgtaacttt tcgaggaaat ttcttatttt
     2701 ttatgaatca tgaaacctgt cgcctgttga ttggccataa tggtcatatc tgtaatctga
     2761 acacggcgag gctgactggt cacatagact actgtgtctg caatatcctg agcttgcaag
     2821 gcttctattc cttggtaaac ggacgcagcc cgctctttat caccatgaaa acgaacagtt
     2881 gagaaatctg tttcgacaat cccaggctga atggttgtca ccttgatatc cgttgcgatg
     2941 gtatcaattc gcagtccatc cgaaaaggtc ttaaccgcag ccttggtagc tgagtaaaca
     3001 gcggcaccag cataggcgta gattcctgcg gttgacccca tattgataat atgaccttga
     3061 ttgactttta tcattgctgg caagaaacag cgagtaaccg ccatcagacc tttaacattg
     3121 gtatccaaca tggtcaacat atccaactcc tcatagtctt gatagggagc caagtcaaga
     3181 gccagtccgg cgttgttgac caagatatca atcctcccta tcgtttctag aatatcagag
     3241 caaacagtct tcaccatgac catatccgtc acatctagtg gaaaagtcca gacggtttga
     3301 tttggaaagc ttactgcaaa ctccgacttg aggatttcta atctgtctat ccgtcgtcct
     3361 gttagaacga catcctcacc ctgctccaga taagcacgcg caatcgcttc accgattcct
     3421 gaggttgctc ccgtaatcac tacatttttt gccatcttat ttccttctat cagatgctga
     3481 caagttccta ggcagtccag tgtttcgctg ggtcgaacgg tgttccgaca acttggtctt
     3541 ctgataattc aagcacccca cgtttttgcg gagcatttgg caaatgcaat tcacgaggac
     3601 tacacatcat cccaaaactc ttttcaccac gaagttcgcc tgggaaaatg aaattccctt
     3661 ttggcatcat ggcaccagga agagccacaa tggttttcaa cccaacacgc gcattaggtg
     3721 ctcctgcaac gatttgcact atcttgtcac ttgcgactgc aacttggcag atgttgaggt
     3781 ggtcactgtc tggatgagct accatctcga caatttcacc aacaacaaac ttaggttcct
     3841 tatcattaac aatttcttct gtaaaacctt ccgcctgtaa ttcttggttc aaacgagcga
     3901 cttgctcatc tgataaaaag acttgaccgc gctctgcaat ttcaaacaag ctcgaaacct
     3961 caaaaatgtt ccaagctact gtttccccat tttctttgag gaaaacacgg gctaccttgc
     4021 ctttgcgttc cacattcagt ttggcatctc cgctattttt cacgatgacc ataaggacat
     4081 caccgacatg ttctttgtta tacgtaaaaa tcattgtttc ctttttctcc tatttcaatc
     4141 ctgctaaaaa atcgttaatt tgctccttac ttttacggtc gcgattgaca aaacgaccga
     4201 tttccttgtc cttttctaga acaacaaggc taggaattcc gtaaacatcc cagagtttgg
     4261 ccaaatccat atactgatct cggtccattc gaataaaggt gaactctgga ttggtctctt
     4321 caatctctgg taaggcagga taaatataac gacaatcgcc acaccagtct gccacaaaaa
     4381 ggaagacctt cttgcccgct ttttccacta aagatgctaa ttcttctaaa cttgctggct
     4441 gtatcataag acttcctcct catagactag gtcttcattt tcatagacaa aggtataatg
     4501 acggccatcc tcaaaaatga cgccaccaag caagctctct agactgcttt catagacttg
     4561 aacatagagg gtcgcaattt cccccatgtc tgaaaaatgg tctcgcacaa tctctgtcaa
     4621 ctcttcctga gtcttcatga gcttacggtc atctgcaact tttttcgtag caagagcaag
     4681 gcttccgata cctagcagag ccaagcctgc catccacatt tttttagctt tcataccatt
     4741 cattttaaca caaaaaaggc ttcaggacaa atgaggaagc agcagaaaag caagtaaaaa
     4801 gcctcttcct ttaaggaaaa ggacttctta tactaagagc aaactagaaa gctagccgca
     4861 ggctgctcaa aacacggttt tgaggttgta gataaggcga cgttgacgtg gtttgaagag
     4921 attttcaaag agtattattc ttattgccag gcacctaagt tgccaacgta gtaaccatca
     4981 ggtgtgtagg tattgcgaag catcttacct gatgaagcca gataatacta cttgccattg
     5041 tctttgaccc aatcattcgc aatcatggca ccagaagaac ttacataata ccattctccc
     5101 ttgtcataaa cccaagtact gactttcatg gttcctgagc aattaaaggc aaaaaaactg
     5161 tccaatatca ttcgtttttt aaaagcattt gacactacat catctacgct gtaggacata
     5221 gatgcatcaa acgtaaaagc caaaatatcg aaaaatatac aacttttaaa ggcagcattt
     5281 cattttttaa agtctaacaa ccatagaact gaaatcagag caaggcatca atttcctact
     5341 cttagtacgt ctattttgat ggttgaagtg aagatttttt tatttaacgt agacaatttc
     5401 caacttccca aaagccacat ctccacggat aatcaaggtt ttgctggttg gggctacagg
     5461 agcgtcagcc ttagctgcac caaaggaggt ttctactttc aaatctacac gccagtgttg
     5521 tggaacatag acggttgcat ttccgaaggc cacttcaata tttaaagttg caaaatcacc
     5581 tagcatctct gcattatcat agtagatttt agcatcccca aaagcgactt ccacttggtc
     5641 atctacgaga tcttgatctt gcttatagaa ggtcccgcta ccaaaagcga cttccttatc
     5701 cgtgacgact gtttttttcc cattgtacca ccattttttt tcattccaga acttacttga
     5761 atgcgtcaga taaccaacac caagtaccac caagatgcta gcccaaataa gagaatgatt
     5821 ggtaactggt aacaagtcat aagcgtaatt tgcaatgatg atcgccagta aacctgtaaa
     5881 aactgccgaa gtgagatgac gtctaaggat ggactcaatg gacttataag caaaaaaaac
     5941 aatacctagt aaaggccata ttttaccatc caaagaagga attccaaaat tcccttgcag
     6001 caagatccaa gctgctaaaa ccaataaaac aataccaaat gctttctttt tcatgttttt
     6061 tacctcatgt ttcttagatt ttcttttagg agggattggt aatgccgtga gacatgaacc
     6121 tccttgtgcg tctgataaaa ggaaatggtg cccgttcctg aaaaggactt gtccactgag
     6181 taaatctgac ggatgtttgc gatcgttgac ttggaaactc gattaaaata gcgaggcaag
     6241 atagactcca actcatagag cttgaggcga acctcataag cttccttctg gttatgagcg
     6301 tagatcttgc tcccttctgt ttcaaagaag agaatttctg acaggtctag ataatattca
     6361 cctgtcccct tgtaaaaagt caacctcgga gcctttgact cttgcaagag ccgttgcaag
     6421 tctgcaattt catctgtcaa agtgggggtc ttgatgacaa tttcagtctc ctctaaattg
     6481 ccgtcaatct caattcgtaa cttcatcaca tctcctttct gactctacta tatcaaagct
     6541 aagttaggaa tacaagggca aaaaagcaag tggtcaattt gaagcagtaa gtggttgcaa
     6601 gaccaactta acttacaggt caaaatagaa agaaaagcac accccacgca agaccacaaa
     6661 tataaccaac tactacatcc ttgggataat gtacaccacc taagactctc acgagaccga
     6721 ggagggctga caagaccaac aagataaagc ccacagttag actagcatgt aagcaagtca
     6781 tggagataat ggttgctgaa aagacatgac gactgggcat agactgacca ggactatctc
     6841 tgtcaagcaa gggtttaata tcccattcct cataaggcct aggggcattg attttcttac
     6901 gaagaaggga taaaatcaca aaacctgtag cagggataaa cacataaacc ccaacttgct
     6961 gaccaagtcc tagttgcagg taagtggtga ctagcaagat cagatagacc aggggcatgg
     7021 cgactgtcat caaacgattg aaactgcgta ataggaataa aagaattgga cgactagtta
     7081 gtctggagct gatatttcga taccattctt gataattttt catttatgct tctcatactt
     7141 ttctagaact tgttgagatg ttttcccctt ggcaagccaa tccactagct tgtccaagcg
     7201 acgtatttcc tgcatcagag gatcatcaat ttcctcaata cggacaccgc aaatcttccc
     7261 tgtaattgca attcgttcag ggacataata tggtgcttgt cgaaaaaaat ctccgtaagt
     7321 aacatcccta tccagacaag caagaacgtc actcacttca taccctgtca accaactggt
     7381 cacttggtga actgactctg cctctccacc ctttcgctca acttttgcaa tcaaggctaa
     7441 atagacagca gcaaatttca tattgtataa tttctgactc atacttctct ctttctatgt
     7501 gtactagtat aaataagaaa aagaaggccg tcaagccttc ttttgattta ttcttctgct
     7561 tcatcttctg taaattgact attgtacaag tcagcgtaga agccacctta caccatcagt
     7621 tcctcatagt tgccttgctc gatgatattt ccatctttca tgaccaagat caagtctgca
     7681 tttcggatgg ttgacaagcg gtgggcaatg acaaaggatg tgcgtccttc catcaaacgg
     7741 tccatggctt tttggatcaa ttcctctgtc cgtgtgtcaa cagaagaagt cgcctcatcc
     7801 aaaatcaaaa gcggtgcatc cttaagaagg gcacgagcaa tagtcaatag ttgtttttgt
     7861 cctacagaca aggtcacggt gtcatccaag atggtatcat agccatctgg caaggtcata
     7921 ataaagtggt gaattcccac agccttacta gcttccatca ttcgttcatc actaatccct
     7981 atttgattat agatgagatt gtctcgaata gttccttcaa agagccaggt atcctgcaag
     8041 accattgaaa aggcatcatg cacttctgaa cgcgtcatag ccttggtatc cacaccatca
     8101 atgcgaatac ttcccttatc aatctcatag aatttcatca aaagattgac aatggttgtc
     8161 ttaccagccc cagtcggccc aacaatggca accctttgac cagcatgagc tgtcgcagag
     8221 aagtcatagt cttgaacatt gacaccgtcc accagaattt ctcctgctga cacgtcgtag
     8281 aaacgtggaa tcagattgac cagagttgat ttaccagaac ctattgaccc aataaaggcc
     8341 actgtttgac cagtttctgc tttaaagcta acatgttcaa taactgcctc cgaatttgcc
     8401 gcatagcgga aggtcacatc cttaaactcg acctgacctt tgaagttttc atcagtcagc
     8461 tgcacttgag cagggttttg gatagaagaa tgcaaatcta aaacttgatt aatccgctta
     8521 gcagagacca tagttcgggg aagaacgatg aagagtgctc ccatgagaag gaagtccatg
     8581 acaacctaca tggcataaga catgaaaaca atcatgtcac taaagagagg cagacgcgct
     8641 atcggagcag cgtcgttaat cacataggcc ccaatccagt aaatcgccac actcaaacca
     8701 cttgaaatcc ccatcatgat aggattcaaa atagccataa gacggttgac aaacaaattt
     8761 taacgggtca attcatcatt tactgctgca aatttttcat tttgataatc ctctgcattg
     8821 taggcacgaa cgacacgaat acctgttaaa ctctcacgag tgatactgtt cagtttatct
     8881 gtcagcccct gaatcaagga ctgttttgga aaggctagcg tcatcaaaac ggtcgtcatc
     8941 aggacgttga caatcactgc cacaagtacg gcccagagtc agtattctga atgacctaaa
     9001 atcttcccaa tagcccagat agccataatt ggaccacacg ttaccacttg caagtccata
     9061 gtaatcaaca tttgaacttg agtaatgtca ttggtagtac gcatcaagag gctaggaatt
     9121 gaaaatttct taatctctgt ctgcgagtaa tccaaaactc ggttaaaaat atcacttctc
     9181 agcctactag tataagaagc cgccactcgg gatgcaaaaa atccaactgc aactacggac
     9241 aagaaggcaa gaaagggcat tcccatcatc atgcttgccg gctgccacaa ctcatctaaa
     9301 ttagtttctt gactacctag caaatccgta attttcgaga tataggtcgg cacttccaac
     9361 tctagataga ccgaaaagca agtaaagaga atggctagta aaatcatccc ccattctttt
     9421 ctactaattc ttttggttaa tttctttatt ctctcctcct attcccttga tattttgcct
     9481 gtagttgacc gagaactttc tcaaaaatca gtaattcatc ttcatcaatg tcttccatca
     9541 actgcttgtc tatgcgttca aaaaaagcct taacctgttg catctgagaa cgtgctttgt
     9601 ccgtcagacg aacaaactta gcccgcttat caacaggact cgcctccaat tccaccaaac
     9661 cattttgcac tatacgctta accagattac tagcaacaga cttggtaata ttgagttcct
     9721 gctcgatatc tttaatcaag accaagtctt gatttttcta gcgattatcc aaaaaacgca
     9781 caacctgacc ttgcggccca cccataaatt caatgccgca acgtttggct tccttttgca
     9841 ccatcaggta aatttgatga ccaaaacgct taaagactaa catcggttta tccataatct
     9901 cccccttcta aataaaaata gttctctgga gaataattaa atttctatga gaactatttt
     9961 cttgattaaa aaaatcccaa gtgattttct cacttaggat catgttctat aggttaaatt
    10021 aaaacccatc tacgttcgta taaatctttt ggacgtcttc gtcgtcttca agaacgctgt
    10081 aaagtttttc aaaggtttca aggtcttcgc ctgacaattc cacttctgac tgaggaatca
    10141 tttccaattc agtcacttgg aattcttcaa taccagactc acggagagca acgatagcct
    10201 tgtgaaggtc agttggcgct gtgtaaactg tgattgtacc ttcttgtgct tctacgtcat
    10261 ccacatccac atccgcttcg agcaattgct caaagactgc gtccgcatct tcacctccaa
    10321 atacaataac acctttgttg tcaaaaaggt aagaaacaga acctgaagcg cccatgtttc
    10381 cgccgttttt accaaaggct gcacggacat tggctgctgt acggttaacg ttagaagtca
    10441 aagtatccac aattagcata gagccatttg gcccaaaacc ttcgtaacgt ccttctgtaa
    10501 aggtttcgtc tgtgtttcct ttggctttat caatcgcttt atcgataatg tgttttggca
    10561 cttgggcttg tttagcacgg tcgataacga atttcaaagc tgagtttgat tctggatctg
    10621 gatcaccttt tttagctgct acatagattt ctacaccaaa ttttgcatat actttagagt
    10681 tagctccatc tttagccgtt ttcttggcta cgatattggc ccatttacgt cccattagga
    10741 atctcctttt ttcacatttt aatctttctt attataacac aagttttttt gattttcact
    10801 agaggaaatg gattttatta gcaaatcaag ctaggatagc actttacctg ctaagatggt
    10861 cttgcctttc tatctttatc aacagacact catccacatt caaaaaacaa actagaccat
    10921 tatctgcaaa tagaaagttt cagccaagtt tgacaaagtc agctcaaatt actgtttgaa
    10981 gtttgtagat ataagcgaca aaaacaatca tactgcacct tttgttgaca gtctactcca
    11041 gacatatcat agttcaagta aatactttga aattcaacag ttcttatagg cgctattgta
    11101 ttctaagaaa tcaatagaag agtttctaag caaacctcta atactcaata aaaatcaaaa
    11161 agcaaactag aaagctagcc gcaggttgct caaaacactg ttttgaggtt gcggatagga
    11221 ctgacctggt ttgaagagat tttcgaagag tataatttac gtgttcccaa gatggagaaa
    11281 ttagactagt acactggcac ttctaaacca ttgctagcaa ttgatttgtt catatttaat
    11341 ttcatttttt ccataaatgg gtattagata taaacagcaa aatatttccg atacgtgtca
    11401 ttcttgaatt tccaatcatc taaaacaagt aaaggataat caatcccctg tatatcaagg
    11461 aattggctac cctttttact tttttacaca ttctgtttga tagattcatt ttaacatcac
    11521 gagcatactc caatggaaat cgctaggcaa gagataaact ttcagatatt cgcagagagc
    11581 tcatcgcctc tttttgtcgc aaacattctt ctctcctaat cattttctac cttatcctct
    11641 acctgaggat agagagttgt tccccaaata gaaatcgtcc gcttacgcac tagtggcaaa
    11701 tcggtttttt cataaaccgt acgccaccat tcccaggcaa gcccggtaca ctctctaatt
    11761 ttgacagaga gattacgaac attccctttt aaaggaatac tagtggtaaa gtgagccgtc
    11821 aaatcctgcc catttctgtc ccaagcctta ggagtcaaga cttccttacc ttgatgatca
    11881 taggataatt catcccaagt aatataatat tgggcaacat aggcaccact atgatccagc
    11941 agtaaatctc cgtttctgta agctgtaacc ttagtctcaa catagtctgt actattttga
    12001 aaggtcgcaa ctacattgtc acgtaaaaaa gaagttgtat aggaaatcgg caagcctgga
    12061 tgatctgctg taaagcgact gccttcttga atcaagtcct ctaccatatc caccttgcct
    12121 gttacaactc gggcacccga acttgggtcg ccccctaaaa taaccgcctt cacttctgta
    12181 ttgtccaaaa tctgcttcca ctctgtctga ggagctacct tgactccttt tatcaaagct
    12241 tcaaaagcag cctctacttc atcactctta ctcgtggttt ccaacttgag atagacttgg
    12301 cgcccataag caacactcga aatatagacc aaaggacgct ctgcagaaat tcctctctgt
    12361 tttaaatcct ctaccgttac agtatcttga aacacatctc ctggattttt aacagcatct
    12421 acgctgactg tataataaat ctgcttaaaa ttaacaatct gaatctgctt ttcgcctgaa
    12481 tggacagagt taaaatcaat atcaagagaa ttccctgtct tttcaaagtc agaaccaaac
    12541 ttgaccttga gttgttccat gctgtgagcc gtgatttttt catactgcat tctagctggg
    12601 acattattga cctgaccata atcttgatgc cacttagcca acaaatcgtt taccgctccg
    12661 cgaacacttg aattgctggg gtcttccact tggagaaagc tatcgctact tgccaaacca
    12721 ggcaaatcaa tactataagt catcggagca cgatcgaccg caagaagagt gggattattc
    12781 tctaacaagg tctcatccac tacgagaagt gctccaggat agaggcgact gtcgttggta
    12841 gctgttacag aaatatcact tgtatttgtc gacaagctcc gcttctttct ttcgataaca
    12901 acaaactcat cgggtagctg attaccctct ttgatgaaac gattttcaat actttctccc
    12961 tgatgggtca agagtttctt tttatcgtaa ttcatagcta gtataaagtc atttactgct
    13021 ttatttgcca tcttatacct cctaataagt tcctggattg agttgcataa actcagactt
    13081 gttcagcgaa atcagccgtg gttggactaa gtgatccaaa atttcctcgt acaattcttc
    13141 tgagacattg cgtcgccgtc tggctagata agaagtcgga ataaccgtat tatccaacat
    13201 aaatacctta tctaagtcaa tcaaggttgg tcttgtaaaa ggattacgag ctagatccgg
    13261 ctcttctatc ataaagttct tgaccaaacg tctggtcaag agagctggtt tgaaggtctg
    13321 atttttaacc aactctttgt ttttagtcat gctgttgtca atacagatat acatatgatt
    13381 cttcacagcc aaatcgctac taatagtcgg aaaaggcaaa taaagagcta caacatctcc
    13441 tctcttaatc aagcaagagc accccctttt ctcctaatgt aacatagaca ggattgacca
    13501 agtcttctga ttgactcaga atttccaaag tttgagtttg gcgcgctgtc aatttagtag
    13561 catcttgtct cttcaataca aaatgcttgt cgccaataac cttgacaata taatccttct
    13621 ccaaagctga ctggtaaatc cacatcagat gttgtctgtc ctgagaactc aagagagaag
    13681 gattttcaag cctcccgata gtctgataaa aatcaaaaac aggagctaac tcctgccaat
    13741 ctgattggct agttgtcaag gctagaaaaa gggctttgcg agctgatact tcttggttag
    13801 ccttgagagt tactttcccc tccaagtttt ttagaaatcg ggaaactcca gaaagcaaat
    13861 ttttctctaa ctgcgagaaa taaaaacctt tcgttcccag acataagtct ttcatgtcgc
    13921 tttctctagc aaataagagc tcaaacattt gatagtaaaa gaaaaatatc tggcactggg
    13981 tcgcgctcat cttttcctta tcggcttctt tttttaacca gagcaagggc gacaggtagc
    14041 tggattgaga catttcctct acctcctact cttttttaac tggagcatct gcactagctg
    14101 ccacttcttt tgactggata ctttcccact ggttaatctc ctctgagata agaccttcgc
    14161 atgtcttgac aaatagggca aaagccttgg tctttcctgc atatttctcc gtttggcatt
    14221 gatagaggaa tttttctttc tccaggagtt gcgcagtttt ttggtaagaa atccaatttt
    14281 cctttgcatt atacaaattg ataatcccct cacacagcaa gccgagactg gataaggcaa
    14341 ccgaaatcaa acggtagcga tcacctggca taggaatagc acaaaagaca gctatgagga
    14401 aacctgccac gatttctgtt atttttaata ccttatagcg cctacgatgt tgaacgcttt
    14461 tctttaaaaa atgagctatc tgtacgtcta atcgctctgt caggtacatt tcttctggcg
    14521 tcatattcgt aactcctttc atttactttg ataaccatag tataacatat ttgaatatca
    14581 aagtatagta aaaactggac tataacttat tagactccct gcgaaacaaa atatggtata
    14641 gtagttctat gaattatgaa gcaagtaaac aattaactga tacacgattt aagcgtcttg
    14701 ttggtgttca gcgtaccact tttgaagaga tgttagctgt attaaaaaca gcttatcaaa
    14761 aaagtcggac aagctggtaa aatcttggct gacagtaatt atcaagggct catgaagata
    14821 tatcctcaag cacaaactcc acgtaaatcc agcaaactca agccactaac agttgaagat
    14881 aaagtctata accatgcgct atctaaggag agaagcaagg ttgagaacat ctttgccaaa
    14941 gtaaaaacgt ttaaaatgtt ttcaacaacc tgtcgaaatc atcgtaaacg cttcggatta
    15001 cgaatgaatt tgagtgctgg tattatcaat catgaactag gattctagtt ttgcaggaag
    15061 tctattatat atatgcacag acatatgaaa tctttttgat acagccttct ttttacatag
    15121 agagacagca gttatgatat atttatccat tcacaacatc ttctgtacca atactacaat
    15181 attggtacat tttgattaca caatcgtttc aaaaaatatg atggaagcct gagtatttta
    15241 tagtaattcc cttcctatca actagatcaa ccagttgagt gttgaatgtt gaaacaccct
    15301 agcctcagca aaggactatg atcagcattt cctagccaat aggacgctcc aaatcaccta
    15361 ttctaagtcc atcactagct tggtcagtaa gatacagact gcaaggcaag actgacgtgg
    15421 ttgatgagat tttggaagag tattacaatc atagattcac cagtagactt gaccgcagat
    15481 ttaactatag tagattgaaa ctagaatagt acacttctgc ttctaaaaca ttgttagaaa
    15541 tcgatttgac tgtcctgatc aatttgtcct gttctcgttt cattttacta tactaaaaaa
    15601 ccacctgaaa caaatcaagt gactagagga taaaaacaaa gactgggcaa aaagttttga
    15661 aaagcaaaaa acgcataata tcaggtcttg aaaaaccttg atactatacg tttgattgtg
    15721 ggaagattga cttcattttc tcctgaaatt gaagtttttt ctagtttcca gatatagacg
    15781 aattcaatat agccatctcg ctacaattat tttaaccatc gagaaaattt ttcagaattt
    15841 caaaaatttc attttgatcc aatgaaatgt catcattttg aagaatagtt gacttcacag
    15901 gctctaattc tatcacaaag cggtgcatgt ctgcttttac cgcactactt gatattatag
    15961 ccgataactt ttcatctcct agcaaggaag ctgtcaaacg ggtaatgtca ttcaaatgct
    16021 ttttaatgga cttacttaaa tcttgagcac ctgtagcaga gcgctctctc atatccagcc
    16081 aagctttagc cttaaaaata att
//
LOCUS       DAVIME010000050        15073 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVIME010000050 DAVIME010000000
VERSION     DAVIME010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15073
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.050"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..962)
                     /locus_tag="VV588_001732"
     CDS             complement(<1..962)
                     /locus_tag="VV588_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084028.1"
                     /translation="MNVFELFGKIGINNKPANKAIDETTGKAEGAHSKLSVIFGKIGN
                     LAVKAGKVMATGLAVGITAISSLIGAAVKNYAEYEQLVGGIETLFGAGGKSLEEYAQS
                     VGKSVDDASSEYKKLINAQEDLLNKSKIAYKTAGLSANEYMETATSFSASLIQSVKGD
                     TEKAAKLADQAIIDMSDNANKMGSSMESIQNAYQGFAKQNYTMLDNLKLGFGGTKEEM
                     QRLLDEAGKISGVKYDISSFADITEAIHVMQVKMGIAGTTSKEAASTISGSLGMVKAS
                     WENFLTGMSDPEQDFEDLVDSLTESIGIALGNIIPKLVQALPRV"
     gene            complement(967..1176)
                     /locus_tag="VV588_001733"
     CDS             complement(967..1176)
                     /locus_tag="VV588_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084029.1"
                     /translation="MYLLDEQDKEELTDIWKSKEINMSLADFIKKYSKKSYIEKQSKK
                     QQTIKKDNEAIALAESILKLPGKGG"
     gene            complement(1272..1700)
                     /locus_tag="VV588_001734"
     CDS             complement(1272..1700)
                     /locus_tag="VV588_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084030.1"
                     /translation="MSEKLEMRELNGGDIFTMLSIIGKLDIKEEVVALIERQYATGKN
                     VVPLADHQKKKPTKKEQEEASLSYQKRGMVLATDIGFAILKHVGDAKNEVNKFLADLT
                     STSQKEIESLNMASYTKLLFDFGKKAELKDFFQSIASLLD"
     gene            complement(1710..2327)
                     /locus_tag="VV588_001735"
     CDS             complement(1710..2327)
                     /locus_tag="VV588_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084031.1"
                     /translation="MGKTAVKRTGYSANTPKHYLINAGAIYKNLEWNATGGEGSKGQW
                     EGELLGATAGGNKVTIEQNYRVIDIDGVFTPAVGQKILESQTAKLETNVKELTAENIR
                     LSINGKIADSDGVDAPTGYKVISGKAKLENTDYIKNLGIVGTMSGTDDPIIIIIDNAL
                     CTSGLDFETKDNDEAVISMTFEAHANEGQVDDLSLPCRIYFPNIN"
     gene            complement(2328..2696)
                     /locus_tag="VV588_001736"
     CDS             complement(2328..2696)
                     /locus_tag="VV588_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084032.1"
                     /translation="MKEVIKTILKELKSLNTESYYIKNSAQVVKYPYAVFSLSLTNID
                     QHADSCYMDVDIFCNEGLDQVQIETLSESIKMHFRHFNKILEDCYMRMQFQSMQTVQT
                     NLDNLQRRNLRFYIKIDWRK"
     gene            complement(2697..3104)
                     /locus_tag="VV588_001737"
     CDS             complement(2697..3104)
                     /locus_tag="VV588_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU7084033.1"
                     /translation="MKFVDNSTTVKRELERAAIRGLIKAAMLVEAQAVLLVPVGETGD
                     LRGSIGYKVNESELVAYVGTNCEYAIYVEFGTGDFAENGNGRKGGWVYRTPKGEVFFT
                     YGMPPQPYLRPAFRENQKAIREILANCLKELGG"
     gene            complement(3104..3412)
                     /locus_tag="VV588_001738"
     CDS             complement(3104..3412)
                     /locus_tag="VV588_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEU7084034.1"
                     /translation="MMMAFNLLKPTSNGENELGQEIFEHKQVAVFFGYMDMLDGSEST
                     DKLAYIADSTHVILTKGRTVNAEIEDKIEVNGKTYEVTYVDDPVNIGHHLEIYVKGAH
                     "
     gene            complement(3409..3939)
                     /locus_tag="VV588_001739"
     CDS             complement(3409..3939)
                     /locus_tag="VV588_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084035.1"
                     /translation="MIISLDEALKLDATATQETCDGLETMVRKLTNNNFQLIKFRLRD
                     LKLSENTIKSSSGRMDVFRPGDTIEINGTDYNDGLYIVKSVSDSVITVHGEFIAEINS
                     GAIATKINYPADVLAGVKKLIAYDVKMRDKVGIKSETIARWSVTYYDVTAAESSEGYP
                     VSLLGFLNKYKKLRWS"
     gene            complement(3972..4199)
                     /locus_tag="VV588_001740"
     CDS             complement(3972..4199)
                     /locus_tag="VV588_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084036.1"
                     /translation="MRKFKRLNVIKETDSDLVADRLLEEGFEEIMGDNEPEGLSRDNI
                     KAQLDAAGIEYAKNAKTEILLEILEASKPGE"
     gene            complement(4210..5127)
                     /locus_tag="VV588_001741"
     CDS             complement(4210..5127)
                     /locus_tag="VV588_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084037.1"
                     /translation="MPNTLEYSKIFQPALDKQIVQESTTGWMEVNSKLVQYNGGNEVK
                     LPSIVMDGLADYDRNTGYVDGAVTLKWETYKLTQDRGRKFQLDAMDVNETNFVATAGT
                     IMGEFQRTLVVPEIDAYRYSAIASKAIAAEQNRAATITDTNILTELLKDIAKVKEVVG
                     NTSKLKIVMSETMLINLGLDDKAAKRMSTVNNAAAGEVATVITKIDGHEITTTQQSLL
                     QTAFKFNDGKTSGQEKGGFVKDSSAKAINWLIIAENAPIAVSKTDTVRVFDPITNQRA
                     NAWDMDYRKYHDIWIPKSKEKSIFVNTVA"
     gene            complement(5146..5685)
                     /locus_tag="VV588_001742"
     CDS             complement(5146..5685)
                     /locus_tag="VV588_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEU7084038.1"
                     /translation="MKRDFLVGLGLSDDVINQIMVEHGKSVQGVQSKLDEAESKLEEA
                     NSTLDTLKQSNKDNEDLQNELKTYKEKVSQLEADAKETTKKQTIKDALGNVKATDVDY
                     LMYKLGDVELAEDGSIKDLDSKIKDLQTNYPTFFQISEPEQPDNGFKSLGGADIPPGG
                     KIDPNQSMANEFSQALGLK"
     gene            complement(6045..7616)
                     /locus_tag="VV588_001743"
     CDS             complement(6045..7616)
                     /locus_tag="VV588_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084039.1"
                     /translation="MNRFQREIEFLLKKADKSTDRRLYDLYIDTIKDLKKSLLVDYQR
                     IGELKSSEKLKLSQMTALLEQLERSSSELKKELKNEITGHLIHTGQIAYNELFYEYET
                     SYAGINFALLKEDELRTIIETPIANFKLSERLDDGVVERLKSNIKDDLNRVFLNGDSY
                     AKAAARLAEQGYSSYRRAIMITRTEAGRVQAVAREKAQVEARNLGIDFDKVWVATLDG
                     RTRHNHAELDGAKADKDGYFEINGLRTKQPHMFGVASEDVNCRCRTISRLKDDKTPLL
                     RRDNETGEIVEYRNYQEWEKATLERRLATNERKSIDNRLYRKYHIDNSQTKDISTETL
                     KSVNESLDKLMQKHKGIKPYLKKVTFTDSLADTTASAGIRFNKGKAEFSIKLNHEHFK
                     KPETIQKLIDVRVADGEWTPKNGINGILEHEVIHLREYKAIVKRYGTLNGTNTEAQKS
                     KIRKAFANNELPKEIKETALKNLQIPDENAIIESRLGRYATENAAEFVAEAYSDASNS
                     EIAIEVRRLVDKKWR"
     gene            complement(7570..9056)
                     /locus_tag="VV588_001744"
                     /pseudo
     CDS             complement(7570..9056)
                     /locus_tag="VV588_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894655.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            complement(9072..10460)
                     /gene="terL"
                     /locus_tag="VV588_001745"
     CDS             complement(9072..10460)
                     /gene="terL"
                     /locus_tag="VV588_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HEU7084040.1"
                     /translation="MDKAALKRQAQLELARRNFFYYCQLMAGDFYKSERIYLKQLCDS
                     FQNFMSDDEHNVLIINIGPRHSKSRTAGMFVQWLLGNDNTKKIMTGSYNDTLSTVFSK
                     SVRNAIQEEKADDSITVFSDIFPDTKIKRGDGAMNLWSLEKGYNNYLATSPGGTATGF
                     GADVIIIDDLIKSALEANNANILEGHWEWFTNTMLSRFEEGGKLIIIMTRWHSEDLAG
                     KALSKLPESGYSVKHISMRTYDEETDTMLCEDVLSKESYFRKVKAMGADIASANYQQE
                     PIDIKGRLYSEFKTYVDRPIFKRISAYTDTADTGKDYLASYIYGETMDKEAYILDILF
                     TKEPMEVTEPLLARKLVENEVNLCWIESNNGGRGFARNVERLMRENHGTNQTTVKWFH
                     QSKNKQARILTNATWLMEHVYFPEGWRNRWPELYKSLMTYQREGRNAHDDAQDALTGI
                     AEKITANSSWLV"
     gene            complement(10524..10856)
                     /locus_tag="VV588_001746"
     CDS             complement(10524..10856)
                     /locus_tag="VV588_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084041.1"
                     /translation="MILAKKTKRGRPTKMTQGTLRKLEELFVRGLSDEEACLLADIGT
                     TTLYDYCKENPEFSERKELLKQRVKIRAKLNISKAIEDGDTDLSKWYLSVEIMILRQN
                     KQSHTAEK"
     gene            complement(10919..10991)
                     /locus_tag="VV588_001747"
     tRNA            complement(10919..10991)
                     /locus_tag="VV588_001747"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10956..10958),aa:Glu,seq:ttc)
     gene            complement(11176..11637)
                     /locus_tag="VV588_001748"
     CDS             complement(11176..11637)
                     /locus_tag="VV588_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU7084042.1"
                     /translation="MNKAKELLKELQDLDIDIQSRIDEINELEAGLLSSPKWTDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVIDRKLELGRMINRLKNPKHRTILRKTYINK
                     MYVDDICESMGGMSSPTYYRLKKQAVNELDVILSELIVNDSNGTGMKSKIC"
     gene            complement(11714..12112)
                     /locus_tag="VV588_001749"
     CDS             complement(11714..12112)
                     /locus_tag="VV588_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084043.1"
                     /translation="MKIKKIVAVISVLSALLLLTACRESEKVSYNVSQEADNFNIVRR
                     VAVINTRTDKVEFEVIGRISVETEANEGKRLEILVETAKGVYKKHMVNLTSWNMYVVE
                     DLEGAEVDQYKYEVNYMPESIIPFKVTKKD"
     gene            complement(12114..12401)
                     /locus_tag="VV588_001750"
     CDS             complement(12114..12401)
                     /locus_tag="VV588_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084044.1"
                     /translation="MAKDILTDLAFENFHKCMGITDWKESDEVILVSLANKEQIESDE
                     SYRSAGKCNYLGKRICIFCTQVKKNNYITLHKSFLEKVIKTMESFKDVEEK"
     gene            complement(12463..12711)
                     /locus_tag="VV588_001751"
     CDS             complement(12463..12711)
                     /locus_tag="VV588_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEU7084045.1"
                     /translation="MKNTLIRFLLAWSLIATCLLFMQREAQKPLLVYYTDSKYQITGK
                     VEEKRKIGNLFTITVNGNVFVVNEQKYKNIEIGDNIEL"
     gene            complement(12708..13301)
                     /locus_tag="VV588_001752"
     CDS             complement(12708..13301)
                     /locus_tag="VV588_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084046.1"
                     /translation="MEDTIWLEWIAEVMATKPVGNELLESQRGQEVVDLLLDLESNDF
                     NWHRGDADTFWIDAQMCIKYQLSNAEIKFLAKQQPGVVNYKKHAKERNAYSEMMRGLE
                     KLKELNFPEIYNHSLSPEEEKKKFEEEMAIEQKYISPYQKLDELEKRFFENQFLFGQK
                     VMEAAMKIVSSEKKITVDNFFNIGSHRIKFTVEEVTN"
     gene            complement(13301..13789)
                     /locus_tag="VV588_001753"
     CDS             complement(13301..13789)
                     /locus_tag="VV588_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU7084047.1"
                     /translation="MNKQELIGRIKRLDESYLKTEFVLKLIEQLDEPKPVKVPQFVAE
                     YIEYAKNNYWDLQDLFKFIDDEENKNLQRWFYHECEQETLALAWLFGYEVEGEKRYFV
                     KMKGIAKYKNYLVFGEISRTWFFASVGSNDVTFTHTSKELEEAGFGWVFNCEGIEVEE
                     VE"
     gene            complement(13894..14325)
                     /locus_tag="VV588_001754"
     CDS             complement(13894..14325)
                     /locus_tag="VV588_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEU7084048.1"
                     /translation="MKLVLNIEPKPQSRPRFARRGSFTTTYEDKDMKAWRNHCQLLIA
                     NQYMGQPLLEGALRAKVRFYIKPPQYISKAKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEVEVMEPLSI"
     gene            complement(14322..14657)
                     /locus_tag="VV588_001755"
     CDS             complement(14322..14657)
                     /locus_tag="VV588_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084049.1"
                     /translation="MQRTAVINTPFTIVTSKTEQNIEIVGSSLWSPVAEFVKQDRQLS
                     LDENGDLFEPEYKLVLEAKQSVDMILDSAYAAGEFAKDTKEVQTLFKFIEENKKNLFE
                     ELGFHGVLL"
     gene            complement(14672..14881)
                     /locus_tag="VV588_001756"
     CDS             complement(14672..14881)
                     /locus_tag="VV588_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084050.1"
                     /translation="MEWTDWVDLEPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     MDIKRDCLRIGVPFEDVYPLQTTLF"
BASE COUNT         3988 a         3369 c         2424 g         5292 t
ORIGIN      
        1 atgactcttg gtaaagcttg aaccaatttt gggattatat tacctaatgc aatcccaatt
       61 gattcagtta aagaatcaac taaatcctca aaatcctgtt caggatctga catgcctgtt
      121 aaaaaatttt cccagcttgc ttttaccata ccgagagaac cagagattgt tgaagcagct
      181 tccttcgaag ttgttcctgc aattcccatt tttacttgca ttacatgtat agcttcggtg
      241 atatctgcaa atgaagaaat gtcatactta acaccgctga tttttcccgc ttcatcaagc
      301 aatcgctgca tttcttcttt agtgccacca aaacctaatt tcaagttatc cagcatagta
      361 taattctgct tagcaaatcc ctgataagca ttttgtatag attccatcga tgaccccatc
      421 ttattagcat tatcagacat atcgatgata gcttgatctg caagtttagc agctttttca
      481 gtgtcccctt ttactgattg gattaaagag gcagagaaag atgtcgcagt ttccatgtac
      541 tcatttgccg ataggcctgc tgtcttatat gcgattttag acttattcaa caaatcttct
      601 tgtgcgttta ttagcttctt gtattcgcta gacgcatcat ctacactctt accaactgat
      661 tgagcatatt cttcaagaga ttttccgcct gcgccgaaaa gtgtttctat cccgcctacc
      721 aattgctcat attcagcata gtttttaact gcagcgccaa ttaaactgct tattgctgta
      781 ataccgactg ctaatccagt agccatcact ttaccagctt ttacagctag attgccaatt
      841 tttccaaaaa taactgatag tttactatga gcaccttctg ctttcccagt cgtttcatcg
      901 atagctttgt tagcaggttt attatttata ccgatttttc caaatagttc aaatacattc
      961 acttttctaa cctcctttcc ctggtaattt caagatagat tcagccaaag ctatagcttc
     1021 attatctttt tttattgttt gttgcttctt actttgtttt tcaatataac ttttcttaga
     1081 gtattttttg ataaaatctg ctaaagacat atttatttct tttgatttcc aaatgtctgt
     1141 tagttcttct ttatcttgtt catcaagtaa atacataaaa aaatccaaag cttcttttag
     1201 attttgattt tctaaaagtt gctctggatt cccgtacctc ttgaaaagta tatctcttag
     1261 cttatttaat cctaatccaa tagcgaagca atagattgga aaaaatcctt aagttccgcc
     1321 tttttcccaa aatcaaaaag cagcttcgtg taacttgcca tgtttaatga ctcaatttct
     1381 ttctgactcg tgcttgtcaa gtcggccaag aatttattga cttcattttt agcatcgcca
     1441 acatgtttta aaatagcgaa tccaatatcc gttgctaaca ccatgccacg tttttgatag
     1501 ctaagactcg cttcttcttg ttcttttttg gtaggtttct ttttctgatg atcagctaaa
     1561 ggaactacat ttttcccagt cgcatattga cgctcaatca gtgcgacaac ttcttctttg
     1621 atatctagtt ttccaataat agataacata gtgaagatat ctccaccatt caactcacgc
     1681 atttccaatt tctcagacat aaaaacctcc taattgatat ttgggaaata aatacgacaa
     1741 ggtaagctta aatcatcaac ttgaccttca ttagcatgcg cttcgaaagt cattgagatt
     1801 acagcctcat cattgtcttt tgtttcaaag tctaagccag atgtgcacaa agcattatca
     1861 ataatgataa tgattggatc gtcggttcct gacatcgttc caacaattcc taagtttttg
     1921 atataatcag tgttttctaa tttcgcttta ccagaaatca ctttatatcc agtcggagca
     1981 tctacaccgt ctgagtctgc aatcttccca ttgattgaca atcgaatgtt ttcggctgtc
     2041 aattctttga cattagtttc cagttttgcc gtttgacttt cgaggatctt ttggcctact
     2101 gcaggagtaa acacaccatc aatatcaatt actcggtaat tctgttcaat tgtaacctta
     2161 ttacctccag cagttgcacc aagcaattca ccttcccatt ggcctttgct cccttcacca
     2221 ccagttgcat tccattctaa atttttatag attgcaccag cattaatcaa ataatgtttt
     2281 ggtgtattgg ctgagtagcc tgttcgcttt acagcagttt ttcccattta ttttctccaa
     2341 tctattttta tataaaaacg caagttccga cgttgcaggt tgtccagatt tgtttgtact
     2401 gtctgcatcg attggaattg cattcgcatg tagcaatcct caaggatttt gttaaaatgt
     2461 ctaaaatgca ttttgatact ttcggataat gtttctattt gaacctgatc cagtccctcg
     2521 ttacaaaaaa tatccacatc catataacag ctgtctgcgt gttggtcaat gttagtcaga
     2581 cttaatgaaa agactgcgta aggatatttg acaacctgag cactgttctt gatgtagtaa
     2641 ctctcagtat taagactttt caattctttc agaattgttt tgataacttc tttcatctac
     2701 cctcccaatt ctttcaagca gtttgctaat atctccctta tagctttttg attttctcta
     2761 aaagctggtc tcaggtacgg ttgtggtggc attccataag tgaaaaagac ctctccttta
     2821 ggcgtacggt acacccagcc acctttacga ccattcccat tctctgcaaa atcaccagta
     2881 ccaaattcga cataaatcgc atattcacag ttagtgccga cataagctac cagctcgctt
     2941 tcattgactt tatagccaat actacctcgc aaatcgcctg tttcaccaac agggaccagt
     3001 aacacagctt gagcctctac caacatagct gccttaatca agcctctaat tgcagcacgt
     3061 tcaagctctc ttttgacagt cgttgaatta tcaacaaatt tcatcaatgg gctcctttaa
     3121 catagatttc cagatgatgc ccgatattta ccggatcatc aacataggtc acttcatagg
     3181 tttttccatt aacttcaatc ttgtcttcta tttcagcatt gactgtcctg ccctttgtta
     3241 gaatgacatg agtactatct gcaatatagg ctagtttgtc ggtcgattca ctaccgtcca
     3301 gcatatccat ataaccaaaa aacacagcaa cttgcttgtg ttcaaagatt tcttggccaa
     3361 gttcattctc gccattagag gtaggtttta gaagattaaa tgccatcatc atgaccacct
     3421 cagtttcttg tacttattta agaatccaag tagactgacc ggatagcctt ctgaactttc
     3481 tgctgctgta acatcgtagt acgtcacaga ccaacgtgct attgtctcgg atttgatacc
     3541 tactttgtca cgcattttta catcgtaagc aatcaacttc ttcacaccgg ccaaaacatc
     3601 cgctggatag ttaattttcg ttgctatggc tcctgaattg atttctgcga taaattctcc
     3661 atggacagta atcacgctat cagaaacgct cttgacgatg tataggccgt cattgtaatc
     3721 tgttccgtta atttcgattg tgtctccagg gcggaataca tccatacgcc cactacttga
     3781 cttgattgtg ttttctgaca atttcaagtc tcggagtcgg aatttaatca attgaaaatt
     3841 gttgttggtc aattttcgaa ccatagtttc caaaccgtca caagtttcct gtgtggcagt
     3901 tgcgtcaagt tttagtgctt cgtctaggct aataatcata catacctccg attaaaaagg
     3961 agagtagatg actactctcc tggttttgat gcttctaaaa tttcaagcaa gatttcagtt
     4021 tttgcgtttt tagcatactc gatgccagct gcatccaatt gagctttgat attgtcacga
     4081 gacagacctt ctggttcatt gtcacccatg atttcttcaa acccttcctc taaaagtctg
     4141 tcagctacca agtcactatc cgtttcctta atgacattca gtcgtttaaa tttgcgcata
     4201 agaaacctcc taagctacag tattgacaaa aattgatttt tctttagatt taggaatcca
     4261 aatatcatga tatttacgat agtccatatc ccaagcgttc gcacgttgat ttgtaattgg
     4321 atcaaatact cgcacagtat ctgttttaga cactgcaata ggtgcatttt cagcaatgat
     4381 aagccagtta atagctttag cagaggagtc ttttacaaag ccacctttct cctgtccact
     4441 agttttaccg tcattaaact taaatgcagt ttgaagtaat gactgctgag ttgtagtgat
     4501 ttcgtgaccg tcaattttag taataacagt cgccacttct ccagcagctg cattattaac
     4561 tgtcgacata cgtttagcag ctttatcgtc aagtccaaga ttgatcaaca tggtttcaga
     4621 cataacaatt tttagtttag aagtatttcc gacaacttct ttcactttcg caatatcttt
     4681 caaaagctcg gtcaagatgt ttgtatcagt aattgttgct gcacgatttt gttcggctgc
     4741 aatagcttta gatgcgattg ctgagtaacg gtaagcgtcg atttctggta ctaccagagt
     4801 tcgttggaat tcacccatga tagttcctgc agttgcaaca aagtttgttt cattaacgtc
     4861 catagcatcc aattggaact tacgtccacg atcttgtgta agtttgtagg tttcccattt
     4921 gagtgttaca gcaccgtcaa cataacctgt attacgatca taatcagcaa gtccgtccat
     4981 cacaatagat ggaagcttga cttcattacc accgttgtat tggactaact tactgttaac
     5041 ttccatccaa cccgttgttg attcctgtac gatttgctta tccagggcag gttggaaaat
     5101 ttttgagtat tcaagagtat ttggcataat ttactttctc cttttttatt ttaatcctaa
     5161 tgcttggcta aattcattag ccatagattg atttgggtcg attttcccac caggtgggat
     5221 atcagctcca cccaaagact taaaaccatt atctggttgt tctggctctg aaatttggaa
     5281 gaatgtcggg tagtttgtct gcaagtcctt gattttactg tcgaggtcct taatgctacc
     5341 gtcctctgcc aattctacat cgcctagttt gtacatgaga taatcaacat ctgttgcttt
     5401 tacgttgccc aaagcatcct tgatggtctg cttcttggtt gtttcttttg catcagcttc
     5461 cagttgcgac accttctctt tgtacgtttt tagttcgttc tgcagatctt cattgtcctt
     5521 attagactgt ttcagcgtgt ccagcgtgct gttagcttct tcgagcttac tctctgcttc
     5581 gtcaagcttc gactgcacac cttgaacaga cttcccgtgc tcaaccataa tctgattgat
     5641 aacgtcatca gacaatccaa ggcctactaa aaaatcacgt ttcatacgtt ctccttctac
     5701 gtctagttaa cgtgtgacga ccacgagaat ttgaaatatg ttaaacagtt taacgccatg
     5761 ccgggcgagt tttttgggca aaaagaaaac cgtacgggat tccatacggt taggatataa
     5821 gaaaagcact tagacttctc taggtgctta ttctatatcg tcatcaaaaa caaatttaga
     5881 cctatctttt cgatactctt tgattgtttc gttgcatcgg tctaacaaat cctggtcacc
     5941 tttcgtccaa gtagctttgt actcagattt tacatgccaa tagccatcat ccaaacgttc
     6001 aactctgctt cctaattgta aactagggct aatgagcata aaggtcacct ccatttcttg
     6061 tcaactaatc gtctcacttc aattgctatc tctgaattac ttgcgtctga gtatgcttca
     6121 gctacaaatt cagctgcatt ttctgtggcg tacctaccta gtcttgattc aattatagca
     6181 ttttcatcag gaatttgtaa gttttttagc gctgtttctt tgatttcttt tggtagttcg
     6241 ttattagcaa atgcctttct tattttagat ttttgagcct ctgtatttgt accgttcaaa
     6301 gtcccgtatc tcttgacaat tgctttgtat tctcgcaagt ggataacttc gtgttcaaga
     6361 atgccgttaa taccattctt aggggtccat tcaccatctg cgacacgaac atctattaac
     6421 ttttgaatcg tttccggttt tttaaaatgt tcatgattca acttgataga aaattcagct
     6481 ttccctttat tgaatcttat tccagcgctt gcagtagtat cagctaagct atcagtaaaa
     6541 gttacctttt ttaaatacgg cttgatacct ttgtgctttt gcatcaattt gtctaggctt
     6601 tcattcacag atttcaaagt ttctgttgat atatccttgg tttgactgtt atcaatatga
     6661 tatttacgat acaggcgatt atcaattgat tttctctcat ttgtcgccaa tctgcgttcc
     6721 aaggtggctt tctcccactc ctgataattc cgatattcga caatctcgcc agtttcgtta
     6781 tcgcgtctta aaagcggggt tttatcatct ttaagccttg atattgtccg acatctgcag
     6841 ttgacatcct cgctggcaac accgaacata tgcggttgct tggtccgcag accgttaatc
     6901 tcaaagtaac cgtctttgtc ggccttggca ccgtccaatt ctgcatgatt gtgtctagta
     6961 cgaccatcca gagtagctac ccaaaccttg tcaaaatcaa tacccagatt tctagcttct
     7021 acttgtgctt tctccctggc aacagcctga acccgtccag cttctgttcg ggtaatcata
     7081 attgctctac gataggaact atacccttgt tccgctagtc tagcagcagc ctttgcataa
     7141 ctatctccgt tcaaaaacac tcggtttaaa tcatccttga tattgctttt taaccgttcg
     7201 acaactccgt catctaaccg ttcggataat ttaaaattag cgataggtgt ttctataata
     7261 gtcctgagtt catcttcttt cagaagagca aagttaatcc cagcatagct agtctcatac
     7321 tcatagaata actcgttata agctatctgt cccgtatgta ttagatgccc tgtgatttca
     7381 tttttaagtt ctttttttag ttcactagag gatcgctcca gttgttccaa aagtgctgtc
     7441 atttgactca atttgagttt ttctgacgat tttaattctc cgattcgctg ataatctacc
     7501 agcaaggatt ttttcaagtc tttaatcgta tcaatgtaga ggtcatagag ccgtctatcc
     7561 gttgacttat cagctttctt cagcaggaac tctatttccc gctgaaacct gttcaactcc
     7621 gtcatctgtc acctccgaat tctgattgaa atctcctttg taaccctgtt catcaaacaa
     7681 gcgctcgact tctgcaaaat ccacttctag gatttcacac aaagttttta gaacagtctt
     7741 atcatccaat cgggtagaag ctgtcatgat gttatccaca agaatcttct tagtctcagc
     7801 ttcaatcttc tcagttgtcg cattgtccgt cttgttaacc ataacatcgc gagtaatttt
     7861 tatagtgatt gtcgacgcat caaaagcctt ttcatgcagc tcatttatat tctctacaat
     7921 aagttttagc attctcttaa tgactttccg cagtcggact tcagttttat tacactttaa
     7981 atcaagtaag ctgtatctcg atttgataac aacattagtg atatttccat cacctgtctg
     8041 agaactatcg aagcccattc caaatttata gatggcctct ttatcaatag ttaattttgt
     8101 tttacgtgct tcaacaggaa tattaacagt atgaacttcg atacctccat tctccccaac
     8161 accaacagtt tttttgttct caaattagta actaggttat caaggttatc accttcaaaa
     8221 cctctgacag cataaatcgg gtgatcaaag tcgattaagt tattagatag agaacatgcc
     8281 atcaaatcat aatcatcgat taaatccttg ataggcgcta aatcattttt cttttgtcga
     8341 ttgttttcta aacataggaa tggcacctgg ccgtaacttt ttccaaatag ctcactattg
     8401 ttttttgcga ttatgtgcgg agagggatta attttgatag aatcatctaa ctttaaatct
     8461 ttattgtcga tttgcacaaa ataaaaaatc tcttcttttg tccagagctg aactttagtt
     8521 acgggttttt tcttattttc aatcgtaatt tcatcatcgt aataatagat tacttgttca
     8581 atgttgtaaa atgcatcgta aatcggtatt attttaaaag cgtcagcagt tttaaaactg
     8641 atacggttgt ctgcaccttt tttccaaaaa acatactcaa tagctttttg acttgctcct
     8701 tcaacgagtt cttgtaacat gagttgaaaa tcttcatcta tatactcatt caaatatttt
     8761 tgcaattcag catcttctgt tgaaatttca ataggatttg aaagcaagta ttgtactttt
     8821 tgatccacta actcagtaaa gaactgatga gcaatttttg tattgcttcg attcttctct
     8881 tctacaattt gaccttcgtt gttgaaaaag aaaagtctgt aacctccaat atcatgtaat
     8941 ccattgtagt aatcaatact aacttgcata tcttttttta gatcgcttac acgatcatca
     9001 gcaatcattt tttttacttc agcaactagt tttagtatat cattcgtttc taacattatt
     9061 cctcctatac actatacaag ccagctcgaa ttagctgtga ttttctctgc tatacctgtc
     9121 aaagcatctt gcgcatcatc atgagcattt ctaccctccc tttgataggt cataagactt
     9181 ttatacaact ctggccaacg gttacgccac ccttctggaa aatagacatg ttccattaac
     9241 cacgttgcat ttgttaaaat acgagcctgc ttattttttg actgatggaa ccatttgacc
     9301 gttgtttgat ttgtaccatg attttctctc atcaatcgtt ctacattccg agcaaaacca
     9361 cgaccaccat tattggattc aatccagcat agatttacct cgttctcgac taatttcctc
     9421 gctaataaag gttctgtcac ttccatcggc tccttcgtga acaagatatc taagatataa
     9481 gcttccttat ccatcgtttc tccgtagata taactagcta gatagtcctt acccgtatct
     9541 gccgtatcag tataggcgct aatacgctta aatatcggtc tatctacata ggttttaaac
     9601 tcgctatata atctaccttt aatgtcgata ggttcttgtt gatagttagc cgaagcaata
     9661 tcggcaccca tagctttgac cttgcggaaa taagactctt tgctcagaac atcctcgcac
     9721 aacatagtgt ctgtttcttc atcgtaggtc cgcatactga tatgcttgac gctataccca
     9781 gattcgggta gcttgctcaa ggccttgcca gcaaggtctt cggaatgcca gcgggtcatg
     9841 atgataatca gtttgccacc ttcttcaaaa cgcgatagca tggtatttgt gaaccactcc
     9901 caatgaccct ctaggatatt cgcattattg gcttccagag cgctcttaat caagtcatct
     9961 atgataatga catccgcgcc gaaacctgtt gcggtcccgc ctggtgaggt cgccaagtaa
    10021 ttgttatacc ccttttccag tgaccacagg ttcatagctc catcgccacg cttgattttg
    10081 gtatccggga atatgtcaga aaagactgtg atggagtcat ctgccttctc ttcctggata
    10141 gcgtttcgaa cagattttga aaatactgtt gacaatgtat cattgtatga gcctgtcata
    10201 attttctttg tgttatcatt tcccaacaac cattggacaa acattccagc cgtacgcgat
    10261 ttactatggc gcgggccgat attgatgatc aacacattgt gctcgtcgtc agacatgaag
    10321 ttttgaaaac tgtcacacaa ctgttttaga tagattcttt ctgacttgta gaaatctcct
    10381 gccataagtt ggcagtaata aaaaaaatta cgacgtgcaa gttccagctg cgcttgcctc
    10441 ttgagtgctg ctttatccat cagcaattaa ctttcttaat tcttcagttg atagaccagc
    10501 gaatggattt acttgattaa cagctatttc tccgccgtgt gtgactgctt gttttgcctt
    10561 aaaatcatta tctcgacgct caagtaccat tttgacaagt ctgtatcacc gtcttcaatt
    10621 gcttttgata tattaagttt agctcgtatt ttaacgcgtt gcttaagtag ctcttttcgc
    10681 tccgaaaatt caggattttc cttgcagtaa tcatagagag ttgtggttcc tatatcagct
    10741 agaagacagg cttcttcgtc acttaaacct ctcacaaaca actcttctaa tttccggagt
    10801 gtcccttggg tcatcttggt cggtctacca cgcttcgttt tcttcgccaa tatcatcacc
    10861 acccgttttt tacaacacaa aaagccacac aatgtgtgac cctttgtaag acctctcata
    10921 agaacaacag gacttgaacc tgcaaccaat agggtgaaaa cctaccgctc taccaattga
    10981 gctatgtcct tactgcaagg cgactacaac cttgctagtt tagatactac atttgttttt
    11041 tattttttgt agtcattttt tgcgatatta aaacatccta ctctatcgcc actggtaacc
    11101 caagccagca gtttttcaga agcttttcta ggtcgtcgcc taaggtgcct ttgttcaatt
    11161 cttgatacta ccattctaac agattttaga cttcatgcct gtaccgttac tatcattcac
    11221 tatcaattcc gaaagaatga catcaagctc atttaccgcc tgtttcttca agcgataata
    11281 agtaggagag ctcatgcctc ccatactctc acagatgtca tcgacgtaca ttttattgat
    11341 gtaggtcttt ctcaaaatag ttctatgctt tggattttta agcctgttga tcattctacc
    11401 taattcaagc tttctgtcga taacctcttt cgtatcctgt tctatagcct ctttcattac
    11461 aacaagctga gtatagacgt catcaacttt tctagcttga ccaccttgga ctttgacatc
    11521 agtccactta gggcttgaga gcaaacctgc ctcaagctcg ttaatttcgt ctatacggct
    11581 ttggatatct atatccagat cctgtagctc tttcaagagc tctttagcct tgttcactct
    11641 ctatctcctt ttgtggtatc atagtctttg cgataactat tagctgagac agagagtgtc
    11701 ttggcttttt tatttagtct tttttcgtta ctttaaacgg gataatactt tcaggcatgt
    11761 agttgacctc atatttgtac tgatctactt cagcgccttc aaggtcttct acgacataca
    11821 tattccaact tgttagattt accatgtgtt tcttgtaaac gccctttgca gtctcaacta
    11881 agatttcaag acgtttgcct tcgtttgctt ccgtctctac agaaatgcgt ccaatgacct
    11941 caaactcaac tttatctgtt cgagtgttaa taactgccac gcgacgaaca atgttgaagt
    12001 tatctgcttc ttgactgacg ttataagaaa ccttttcgct ttcacggcaa gcagttaata
    12061 ataacaatgc acttaatact gaaataactg ctacaatttt tttgattttc attttacttt
    12121 tcctccacat ctttaaatga ttccattgtc ttaataactt tttctaaaaa agatttatgt
    12181 agcgtaatgt aattattttt ctttacctgt gtgcaaaaga tacagattcg tttgccaaga
    12241 taattacatt ttccggctga acgataactt tcatctgact caatttgttc tttgttagcc
    12301 aagctaacaa gaattacttc atcagattct ttccaatcag taattcccat acatttgtga
    12361 aaattctcaa atgctagatc cgttaaaata tctttagcca tcattctcct ccgttttcta
    12421 aatcacggtc aataaaccat tgtttgactt tgtctattgt gttcataatt cgatattatc
    12481 tcctatttca atatttttat atttctgctc attcaccaca aacacgttac cgtttaccgt
    12541 gatagtgaat agatttccga tttttcgttt ttcttccacc ttgccagtga tctgatactt
    12601 gctatcagtg taataaacaa gcaagggttt ctgtgcttca cgttgcatga ataacaagca
    12661 agtagcgata agcgaccatg caagcaagaa gcgaattagt gtatttttca atttgtgacc
    12721 tcctcaactg tgaatttaat tcgatgactt ccaatattga aaaaattatc aacagttatt
    12781 ttcttttcgc ttgatacaat tttcattgca gcttccatca ctttttgacc aaataaaaat
    12841 tgattttcaa aaaatcgttt ttcaagttca tctaattttt gataaggcga tatgtacttt
    12901 tgttcaatcg ccatttcttc ttcaaatttt ttcttttctt cttctggaga taacgaatga
    12961 ttatatattt ctggaaagtt aagttctttc aacttctcaa gacctctcat catctctgaa
    13021 taagcatttc tttcttttgc gtgcttctta taattcacaa cacctggttg ttgtttagct
    13081 aagaatttaa tctccgcatt tgaaagttga tacttgatgc acatctgagc atctatccag
    13141 aaagtgtcag catcgcctcg atgccaatta aagtcattgc tctccaaatc caatagcaaa
    13201 tcaactactt cttgaccacg ttggctttct agcaattcgt taccgacagg cttagttgcc
    13261 ataacctcag caatccattc tagccagata gtatcttcca tcactccacc tcctcgactt
    13321 ctatcccctc acaattaaac acccagccga aaccagcttc ttctagttct ttgctggtgt
    13381 gtgtgaatgt cacatcattg cttccaacac tagcaaaaaa ccatgttctc gatatttcac
    13441 caaatactaa ataatttttg tattttgcga tccctttcat cttcacaaaa taccgctttt
    13501 ctccctcgac ctcgtagccg aaaagccaag ctagtgcaag tgtttcttgt tcacattcgt
    13561 gataaaacca tctttgtaaa ttcttatttt cttcatcgtc tataaactta aataaatctt
    13621 gtaaatccca atagttgttt ttcgcatact cgatatattc cgccacaaac tgcggaactt
    13681 tgactggttt tggttcgtct agttgttcga ttaattttaa aacaaattcc gtttttaagt
    13741 atgattcatc taaacgttta attcttccaa tcaactcctg cttattcatc ttcctgctcc
    13801 tttaacttat cttatggctt tccaggtctc caaattcgtg accgcagctt acaaagtacg
    13861 agccaatcag gattgcatct gctcctcatt tctttaaata ctcaggggtt ccataacctc
    13921 cacctctacc tctatccgtg gatttagact gtagaacttg cctacatcat gtagcgctat
    13981 ctgaccatcg tcctggaaga caatccctga catactgtca tatagggctt tttcgtagtt
    14041 gtcaatgtca ggcttcttgc ctacagggat aatctcatcc aggagggcct gctggttctt
    14101 cttggcctta gaaatgtact gaggaggttt gatataaaat ctaacctttg ccctcaaagc
    14161 tccctcaaga agaggctggc ccatgtactg attagcaatg agcaactggc aatgattgcg
    14221 ccaggctttc atgtccttgt cttcgtaagt cgtggtaaaa ctcccacgtc ttgcaaacct
    14281 tggccgtgat tgaggtttag gctcaatgtt caggacaagc ttcatagcaa aactccatgg
    14341 aatcccaatt cttcaaatag attctttttg ttttcttcaa taaatttaaa gagggtctga
    14401 acttctttgg tatctttggc aaattctcca gctgcatagg cgctatctaa aatcatatca
    14461 acagattgct tagcttctag caccagcttg tattcaggct caaataagtc gccgttttcg
    14521 tctagtgata gctgtctatc ttgttttaca aattctgcta ctggactcca caacgagctc
    14581 ccgacaattt cgatattctg ttctgttttg cttgttacga ttgtaaaagg cgtattaatt
    14641 accgctgttc tttgcatttg tttttctcct gttaaaaaag tgtagtttgc aaagggtaca
    14701 catcttcaaa tggcacccca attcttagac agtctcgctt gatgtccatt gtagaaatga
    14761 cgtacttgac gccattgttt ttcttgtcgt agtgtggaaa agtgtatcca tcattttcaa
    14821 tcttggtttt gatgtccgtt ttggtttcag gttccaagtc cacccaatcc gtccactcca
    14881 tgctggtcct cccaactcac aattccagat ataatacacc tgccatctaa tcgacttgca
    14941 agtgtagttc tgttataaag tccgtgactg gtttcaatac agtctccgta gatctttttg
    15001 atttgtacga ttttaaagaa ttctccattt ttaaaatttt cacaaaatca cctgctttta
    15061 agctcatatc tct
//
LOCUS       DAVIME010000051        14967 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVIME010000051 DAVIME010000000
VERSION     DAVIME010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14967
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.051"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..393
                     /locus_tag="VV588_001757"
     CDS             <1..393
                     /locus_tag="VV588_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU7084051.1"
                     /translation="DHVQRNKNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKP
                     ESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLK
                     NNLLFGTQDNNTIMAEAEKLLALLKESK"
     gene            815..1195
                     /locus_tag="VV588_001758"
     CDS             815..1195
                     /locus_tag="VV588_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU7084052.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            1654..2367
                     /locus_tag="VV588_001759"
     CDS             1654..2367
                     /locus_tag="VV588_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU7084053.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2381..3028
                     /locus_tag="VV588_001760"
     CDS             2381..3028
                     /locus_tag="VV588_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084054.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSDDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            3166..3819
                     /locus_tag="VV588_001761"
     CDS             3166..3819
                     /locus_tag="VV588_001761"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU7084055.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3829..4293
                     /locus_tag="VV588_001762"
     CDS             3829..4293
                     /locus_tag="VV588_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU7084056.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4306..5574
                     /locus_tag="VV588_001763"
     CDS             4306..5574
                     /locus_tag="VV588_001763"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU7084057.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5588..5848
                     /locus_tag="VV588_001764"
     CDS             5588..5848
                     /locus_tag="VV588_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084058.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5859..7220
                     /gene="pdrM"
                     /locus_tag="VV588_001765"
     CDS             5859..7220
                     /gene="pdrM"
                     /locus_tag="VV588_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU7084059.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7374..8342
                     /locus_tag="VV588_001766"
     CDS             7374..8342
                     /locus_tag="VV588_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU7084060.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8358..9350
                     /locus_tag="VV588_001767"
     CDS             8358..9350
                     /locus_tag="VV588_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU7084061.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9568..10611
                     /locus_tag="VV588_001768"
     CDS             9568..10611
                     /locus_tag="VV588_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU7084062.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10675..12360
                     /gene="lpdA"
                     /locus_tag="VV588_001769"
     CDS             10675..12360
                     /gene="lpdA"
                     /locus_tag="VV588_001769"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU7084063.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELES
                     EEDGYLIAILKGEGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVITDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12424..13413
                     /locus_tag="VV588_001770"
     CDS             12424..13413
                     /locus_tag="VV588_001770"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU7084064.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13486..14556)
                     /gene="xerS"
                     /locus_tag="VV588_001771"
     CDS             complement(13486..14556)
                     /gene="xerS"
                     /locus_tag="VV588_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU7084065.1"
                     /translation="MKREILLERINKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAINLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         4589 a         2689 c         3243 g         4446 t
ORIGIN      
        1 gaccatgttc aaagaaacaa aaatggtcaa gctgatacca atcaaacgga aaaaccaagc
       61 gaggagaaac ctcagacaga aaaacctgag gaagaaaccc ctcgagaaga gaaaccgcaa
      121 agcgagaaac cagagtctcc aaaaccaaca gaggaaccag aagaagaatc accagaggaa
      181 tcagaagaac ctcaggtcga gactgaaaag gttgaagaaa aactgagaga ggctgaagat
      241 ttacttggaa aaatccagga tccaattatc aagtccaatg ccaaagagac tctcacagga
      301 ttaaaaaata atttactatt tggcacccag gacaacaata ctattatggc agaagctgaa
      361 aaactattgg ctttattaaa ggagagtaag taaaggtagc agcattttct aactcctaaa
      421 aacaggatag gagaacggga aaacgaaaaa tgagagcaga atgtgagttc tagttctcat
      481 ttttttcatg aaaatgtgca aaatatagta gattgaaact agaatagtat acctctactt
      541 ctaaaacatt gttagaaatc gatttgactg tcctgttctt atttcatttt actatatctt
      601 aacagatagt gtaaataaag ataaactatt tactggctaa ttgatcagtt aaacactagt
      661 taaggagtaa tgatgaaaaa aagaacaata ctattattga tggccagtct gttagctctt
      721 gtcttaggag catgtggttt cttggacata ttgatcctgg atcattctca tcaggattac
      781 tctttactgc tattttagaa actggggtgg tttgatggaa agtattggta ttggtcttgt
      841 tatcgtttca cattccaaac acattgcaga aggtgttgtt gaactgatta gtaaagtagc
      901 taaagatgtt ccgattactt atgtaggagg aaccgagggc ggaggaattg gaacgagttt
      961 tgatcaagta gatagggttg tttccgaaaa tccagcagat actttacttg ccttttttga
     1021 cctaggttct gctaaaatga acttaaaaat ggtgactgat ttcagtgata aaagtatcat
     1081 catcaacagg gttccaattg tagaaggtgc ctataatgca gctgctcttc ttcaggctgg
     1141 tgcagaactg tcagttattc aaacacagtt agcggagctt gaaatcaata aataaggaat
     1201 tttactataa ctctttttat aggtaagcta ttgattatct caactataaa atgttaagta
     1261 aatgatttca aaatcagaaa gggattgctt tatgcagttc ctttttattt taacaggagt
     1321 gaaactatag tgtttctaaa ttgtgaatca atcaaaactg attgtgatgg gactattcta
     1381 gctttagaat ccttcaaaaa ttaaaattta aggcaatcaa ttacttggaa gagtatgaaa
     1441 gcatttagtt tataggaatt ctaggtctag aattacacat atatttatga agacagggtg
     1501 ctcgatagtt agtattgttc tattctgaaa gatttgagct gtcagttgta tagaaagtgt
     1561 tcgaattttt tttaagtgat taaattagtt aattgtatga ggtgctttat gatataatgt
     1621 tcttaatgaa ttttcagaaa ggaaaacctc aaattgttct acaaatttct actcttcgac
     1681 ctcgaccaca ctcttcttga ttttgatgct gctgaggatg tggctttgac ccaacttcta
     1741 aaagaagaag gagttgcgga tattcaggct tataaagatt attacgttcc tatgaacaag
     1801 gctctctgga aagacttgga gctgaagaaa atcagtaaac aagagctggt taacacgcgc
     1861 ttttctcgtt tattttctca ttttggacag gaaaaagacg gtagttttct tgcccagcgt
     1921 taccaatttt atctcgctca gcagggacaa acactatcgg gcgctcatga tctcttggac
     1981 agcctcattg agcgtgatta taacttgtat gctgcgacaa atggcattac tgccattcag
     2041 acaggacgtt tggctcaatc tggtctagta ccttatttca atcaagtctt tatctcagaa
     2101 cagttgcaaa ctcaaaagcc ggatgctctc ttttatgaaa agattggcca gcaaattgct
     2161 ggatttagta aagaaaagac gctgatgatt ggagattctc taaccgccga cattcaaggt
     2221 ggcaataatg cggggattga cactatctgg tataatcctc atcacctcga aaatcacaca
     2281 caagcccagc cgacttacga agtctattct taccaagact tgctggattg tttagataaa
     2341 aatattcttg aaaagatcac attttaaagg agattagcta atgactacaa aaaaagctaa
     2401 tattactatt gaagagtaca ttgaaatgtc tgaagttgat tttaatgaag ctgttaatta
     2461 tgaatttaca tctgacactt gtcaattagc aaatagtatt tatcaatctc tttttaagtt
     2521 ttttgataag aaaaatttct ctgacgattt aatttttact tggaaatctc catcattagt
     2581 caaagaaggg gattatattg ggagaaggga ttcacaagta gataatctta gagtaatagg
     2641 aaatatattt ccgaattatc ttactaatcg aaaatatagc ctcaatatga atcgtaatgg
     2701 ctgtatggga gattttcctc atgacttttt tgatatatac ctagatcatg tagcaaaata
     2761 tgcctacgaa caaaaagtta ataatattaa agagtattat cctttaaaaa gagcgatttt
     2821 acaccaagag aatgcattgt attttcgatt tttttctaat tttgacgact ttttagaaaa
     2881 aaattattta aagactatat ggcaagtttc taaagaaact cctttttctg aaatggattt
     2941 taatatgttt aaaaatattt cagaaaagat aatcttcgaa agaggtagta aaatgcttaa
     3001 tgatttaaaa agtaattata aaaaatagcc agtctttata aactgtattc acgtattcaa
     3061 atcgtatata tagtcgattt attaaatctt tagataaact gtaaaaagtg gtttccatag
     3121 ccactttttg ctataataga ggcagtaaaa atgaaggagt cggctatgga acactcgtct
     3181 tggcatgctt tgattaaggc gcaattacct gagggttatt tcgggaaaat caatcagttt
     3241 atggagcagg tctattctca ggggattatt tatccaccca aggaaaaggt ttttcaggct
     3301 ctcttgacaa cactgcttga agaagttaag gtggtaattc tagggcaaga cccctatcac
     3361 ggaccaggtc aagcgcaggg cttgagtttt tctgtacctg actctatccc agctccacca
     3421 tccttgcaaa atatcttgaa agaattgtca gatgatatcg gagttaagaa atctcatgat
     3481 ttgacagctt gggctgagca aggagtcttg cttcttaatg cttgtttgac tgttcctgct
     3541 ggacaggcca atggtcatgc tggtcaaatc tgggagcctt ttactgatgc tgtgattcag
     3601 gtggtcaatc atctagatag accagtcgtt tttgtactct ggggagctta tgcacgtaag
     3661 aagaaggcat tagttaccaa tcctcatcac ttgattatcg aatcagccca tccaagtcct
     3721 ttgtcggttt atagaggatt ttggggttcc aagccctttt ccaaggccaa tgcattctta
     3781 aaagagacag gacaagagcc aatcgattgg cttagataag gagaaaatat gcctcagtta
     3841 gcgacgattt gctacattga taatgggaaa gaactgctca tgctccatcg taataagaaa
     3901 cccaatgatg tccatgaagg gaaatggatt ggtgtgggtg gtaagctaga gagaggagag
     3961 acgccccagg aatgcgcggc gcgtgaaatc cttgaagaaa cagggctcaa agccaagcca
     4021 gttctaaaag gtgtcatcac ttttcctgaa tttacaccag atttagactg gtacacctat
     4081 gtttttaagg tgacggagtt tgagggcgac ttgattgact gcaatgaggg gacgctagaa
     4141 tgggttccct atgatgaggt tttgagcaag ccgacttggg aaggtgacca cacctttgtt
     4201 gagtggcttt tagaggataa acccttcttt tcagccaagt ttgtttatga tggggataaa
     4261 ttgttggata cccaagttga tttctatgaa taaaggagaa agcagatgct actaatcaaa
     4321 aatggtcgtg taatggatcc caagtctggt ttggatcaag tttgtgatgt cttagttcaa
     4381 gatgggaaaa ttatcaaaat tgcgcctgag atcacggaag aaggagcaga aacgattgat
     4441 gctactggtc ttgtggttgc tcctggtttg gtcgatattc atgtgcattt ccgtgaacct
     4501 ggtcaaacac ataaagaaga cattcatact ggtgccctgg cagccgctgc aggtggtttt
     4561 actactgtcg tcatgatggc taataccagt ccaaccattt cagacgtgga gactttgcaa
     4621 gcagttctcc agtcagctgc caaagagaag attaatgtca agacagttgc gaccattact
     4681 aaaaacttta atggtaaaaa cttgactgac tttaaggcgc tcttagaagc tggtgcggct
     4741 ggtttctctg atgacggtat tccgcttgag agcagtaaga ttgtcaagga agccatggag
     4801 gaagccaaaa aactcaatac ctttatcagc cttcatgagg aagatccagg tttgaacggt
     4861 gttcttggct ttaatgaaaa tattgctaga gaacatttcc atatctgcgg tgctactggg
     4921 gtggctgagt acgctatgat ggcgcgtgat gtcatgattg cctatgcaac taaagcccat
     4981 gttcacatcc agcatttgtc taaggaagaa agtgttaaag tagtggagtt tgctcagggg
     5041 ttaggtgcag aagtcacagc agaagtagcg ccacagcatt tctctaagac agaagcactt
     5101 tttttaacac aaggtagcaa tgctaagatg aatccaccgc ttcgtttgga atcagaccgt
     5161 cgtgccgtta tcgaaggtct caaatcaggt gtcatcacag ttattgcgac tgaccacgcg
     5221 cctcatcatg tagatgaaaa aaatgttgag gatattacca aagcgccatc tggtatgact
     5281 ggcttagaaa catccctgtc tctcagcttg acctatttag tagaagctgg tgagttgagc
     5341 ttgatggaat tacttgaaaa aatgacatac aacccagcca agctttacaa ctttgaagca
     5401 ggttacttgg ctgagaatgg tccagcagat atcactattt ttgatgccaa ggctgaccgc
     5461 cttgtggact cccattttgc ttccaaagca gctaattcac cattcatcgg tgaaacctta
     5521 aaagggcagg ttaaatatac catctgtaag ggacaaatcg tctatcaagc ttgataggag
     5581 ttagaatatg aattattttc gaaaacgtag ggagagacaa gcgaaatcta atagtggaat
     5641 ttactgtccc gcagctaatc gttccaaaat tcaatatgaa actaaagaaa aagctgacca
     5701 tgcggttcaa tatgataacg gaggtttagt tagaagctat tattgtcgta catgtgcgtg
     5761 ttggcatact acttcaaaat ctaataaacc tccgctaagt ttgaaaaact atggtctgaa
     5821 actctttggt ttagataaat cagaatagaa agagaagtat gtataagaca aagtgtttac
     5881 gagagaagtt agtattattt ttaaaaattt tcttcccaat cctgatttac caatttgcca
     5941 attattctgc ctcttttgtt gatactgcaa tgacaggtca atacaacact atggacttgg
     6001 ctggtgtatc tatggcaacc agtatctgga atcctttctt tacatttcta acagggattg
     6061 tgtcagcctt ggtgcctatc attggtcacc atcttggtcg aggaaaaaag gaagaagttg
     6121 cgtctgattt ttaccaattt atttatttgg ccttgggcct atctgtggta ttgctgggga
     6181 tggtactttt cttggcacca acaatcttga atcatattgg gttagaagca gcagtagcgg
     6241 cagtagcggt tcgctatctt tggtttttat ctatcgggat tatccccttg ttgctcttta
     6301 gcgtcattcg ttccttgctg gattcgctgg gcttgaccaa actgtccatg tacctcatgc
     6361 ttttgttact ccctctcaat agcggattta actatctctt gatttacggt gcctttggtg
     6421 ttccagaact gggaggggct ggtgctggtt taggaacatc cttggcctac tgggtcttgc
     6481 ttgggatttc tgttctggtt ttatttaaac aggagaagct caaagcctta caccttgaga
     6541 aacgaattcc acttaatatg gataaaatta aggaaggagt tcgtttaggt ctgcctattg
     6601 ggggaactgt cttcgcggaa gtggctatct tttcagtggt tggcttgatt atggctaagt
     6661 tttcgtcctt gattatagct agtcaccagt cagctatgaa cttttcaagt cttatgtacg
     6721 cctttcctat gagtatctca tcggctatgg ctattgtcgt ttcctatgaa gtgggagcca
     6781 agcgatttga tgatgcgaaa acctatattg gtctaggaag atggactgcc ctcatttttg
     6841 cggccttcac cttaaccttc ctttacattt ttaggggaaa tgtggccagt ctttatggta
     6901 acgacccaaa atttatcgat ttgacagtgc gttttttaac ttatagtctt ttcttccagt
     6961 tagcagatac ctttgcggcg ccgcttcagg gaattttgcg ggggtataag gatacagtta
     7021 ttccttttta ccttggtttg cttggttatt ggggcgtagc aatccctgtg gctacgctat
     7081 ttgattctct aacagatttt ggagcttatt cttactggat cggcttgatt attagtttga
     7141 ttgtgagtgg ggcgctctac cgttggcgtt taactgtgat tatgaagaga tttgaatctt
     7201 tagcaaaatc caaacgctaa aaagtttgtg aaaaaatatt cttgataaga aaatcccttg
     7261 ttttcacggg gttttctttt ttattttgtg aaatttcttt tagaaaaact ttgacagtat
     7321 ttgccaaaaa cggtaaaata gtaaggtaag aagaaagtta gaaaggcaag aagatgtcaa
     7381 ctttagataa aaatcttttg ctagaaatgt tccgtaagat ggaagaaatc cgtcgcatgg
     7441 acttaaaaat tgcacaatta gtaaagaaag ggaaagtgcc aggaatgacg cacttttctg
     7501 ttggtgaaga ggcagctaac gtgggggcta tgttagctct caatccagat gatctgatta
     7561 cctcaaacca ccgtggacac gggcaagcta ttgctaaagg gattgacctc aacggaatga
     7621 tggctgaaat ccttggtaaa tacactggaa cctgtaaagg gaaaggtgga tctatgcata
     7681 tcgctgacct tgatgctggg aaccttggtg ccaatggtat tgtaggtggt ggtatgggga
     7741 tcgctgtcgg tgcagccctc agtcagcaaa tgcaaaatac cggtaaaatc gttgtctgct
     7801 tctttggaga tggtgcgacc aatgaaggtg ttttccacga agcagtgaac atggcttcta
     7861 tctggaacct gccagtcatt ttctattgca ttaacaacgg ttacggtatc tctgcggata
     7921 tcaagaaaat gaccaatata gaacatatcc atcaacgtag cgccgcttat ggaattcctg
     7981 gaatgttcat cgaagatggt aacaatgtca tcgatgtcta tgaaggattt cagaaagctg
     8041 tggaccatgt tcgcagtggc aatggtccag tcttgattga aagtgtaact tatcgctggc
     8101 tcggtcactc atcatctgac cctggtaaat atcgtacgcg tgaagaagtg gaattgtgga
     8161 aacaaaaaga tccaatcgaa aacctccgca attaccttat tgaaaataac attgcaagtg
     8221 ccgaagaatt ggaagaaatc caagcgcaag taaaggaagc agtagaagct tctgttaaat
     8281 ttgcagagga aagcccattc ccaccgcttg aatcagcctt tgaagatatt tacgcagact
     8341 aaggagaaag agataaaatg gaaacaaaaa caatgtcctt ccgtgacacc attatccttg
     8401 ctatgtctga ggaaatgcgt cgcgatgaaa atgtgttctt gatgggagaa gacgtcggtg
     8461 tcttcggagg agacttcggt acttctgttg gaatgcttga agaatttggt ccagaacgcg
     8521 tccgtgactg tccgatttct gaagctgcca tctctggagc agcagcagga gctgccatga
     8581 caggacttcg tccaatcgtc gatatgacct tcatggactt ctctgttatt gccatggaca
     8641 atatcgtcaa ccaagctgct aaaacacgtt acatgtttgg tggtaaaggt caggttccaa
     8701 tgactgttcg ttgtgcagct ggtaacggag ttggctctgc cgcccagcac tcacaatctc
     8761 tagagtcttg gtttactcac attccaggac ttaaggttgt ggcacctgga acacctgcgg
     8821 acatgaaagg cctgcttaag tcttctatcc gtgataaaaa cccagttatt atacttgagt
     8881 acaagtcaga atttaaccaa aaaggggaag tgccagttga tccagactac acaattccac
     8941 ttggggttgg tgaaatcaaa cgccaaggaa cggatgtaac agttgttact tatggaaaaa
     9001 tgcttcgccg tgtggttcaa gctgctgaag aattagcaga agaaggaatt tcagttgaaa
     9061 ttgttgaccc acgtaccctt gttccgcttg ataaggatat catcataaac tcagtgaaga
     9121 agactggtaa ggttgttctg gtcaacgatg cccacaaaac aagtggctat atcggtgaaa
     9181 tttcagctat tatttcagaa tcagaagcat ttgactatct agatgcacca attcgccgtt
     9241 gtgcaggaga agatgtgccg atgccttatg cacaaaacct agaaaatgca atgattccaa
     9301 cagttgaaag tatcaaagat gcaatccgaa aaacttataa caaagaatag agttacataa
     9361 gataagttat gtaaataaaa taaagctgac gagaaacttt gtatctttta ggtgcagagc
     9421 tcttcgtcat taatatctta gattagagca cgggctaaaa gctcggaaaa aagataaatc
     9481 tccttggctt catcgaagcc atcgtcgatt tcctattttt cagtcgcttt tgacgccctt
     9541 tgtatcataa atagaattgg agaggtcatg gctgatgaca agctaagagc gactcctgca
     9601 gctagaaagt tagcggatga tttagggata aacctctacg acgtttctgg ctcaggtgca
     9661 aacggtcgtg tccacaaaga agacgtggaa acttataaag acacaaacgt ggttcgcatt
     9721 tcgccacttg caaaacgaat tgccctcgaa cataacattg cttggcagga aatccaagga
     9781 accggtcatc gtggtaaaat catgaagaag gatgttttgg ccctgcttcc tgaaaatatc
     9841 gaaaacgata gcatcaaatc tcctgctcag attgaaaaag tggaagaagt ccctgataac
     9901 gtaacaccat atggtgaaat cgagcgtatt ccaatgacac caatgcgtaa ggttattgcc
     9961 caacgcatgg ttgaatctta cttgactgcg ccaaccttca ccctcaacta tgaagttgat
    10021 atgactgaaa tgttggctct tcgtaagagg gttcttgagc caatcatgga agcaactggg
    10081 aagaagacta ctgtaacaga ccttctttca cttgcagttg ttaagactct tatgaaacat
    10141 ccatacatca acgcttcatt gacagaagat ggcaagacta ttatcactca caactatgtc
    10201 aatcttgcca tggcagttgg gatggataat ggattgatga cacctgttgt ttacaatgct
    10261 gagaagatga gtctttcaga actggttgta gcctttaagg atgttattgg ccgtaccttg
    10321 gatggtaaat tggctccaag tgagttacaa aattcaacat tcacaatcag taatttggga
    10381 atgtttggtg ttcagtcctt tggtccgatt attaaccaac ccaactcagc tatccttggt
    10441 gtcagttcga caatcgagaa gccagttgtc gtcaatggtg aaattgtgat tcgcccaatc
    10501 atgagtttag gattaactat tgaccaccgt gtcgtagatg gtatggctgg tgctaagttt
    10561 atgaaggact tgaaagagtt gattgaaacc ccaatctcaa tgttgattta agagcaagag
    10621 tattcatttt taagatatag ataaaggaag gaagacatgg ccttagaagt aattatgcca
    10681 aaagccggcg tggatatgac agaaggacaa atcgtccaat ggaataaaaa agtcggagaa
    10741 tttgtaaaag aaggagaaat ccttttggaa atcatgactg ataaagtcag catggaattg
    10801 gaatccgaag aagatgggta cttgattgcc attctcaaag gagagggtga aactgtccct
    10861 gtaacggaag ttatcggtta ccttggtgaa gaaagggaaa acatcccaac agctggagca
    10921 gcatcgccag aagctagccc tgtacctgta gcaagtacct caaacgatga tggtaagagc
    10981 gatgatgctt ttgatatcgt tgtgattggt ggaggtcctg ctggttatgt tgcagccatt
    11041 aaagctgccc aactcggcgg taaggttgcc cttgttgaga aatctgaact tggtggaacc
    11101 tgcttaaacc gtggatgtat tccaaccaag acctaccttc ataacgctga aattattgaa
    11161 aatatcggtc atgctgcaaa tcgtggtatc gtgattgaaa atcctaactt cactgttgat
    11221 atggaaaaac ttttagaaac taaatctaaa gttgttaata ctcttgttgg tggtgttgca
    11281 ggacttcttc gtagctacgg agttactgtt cataaaggaa ttggtacaat cactaaagac
    11341 aagaacgtct tggtaaatgg ttctgaattg cttgaaacca agaaaatcat tcttgctggt
    11401 ggttcaaaag tcagcaagat caacgtccct ggtatggaat cttcacttgt catgactagt
    11461 gatgacattc ttgaaatgaa cgaagtgcca gaaagccttg ttatcatcgg tggtggagtt
    11521 gtcggtatcg aactcggtca ggccttcatg acatttggtt caaaagtgac tgttatcgaa
    11581 atgatggacc gtatagttcc agctatggat gcggaagttt ctaagaacct tcgcttgatc
    11641 cttgagcgta aaggaatgac catcttgact ggtactaaac tgcaagaaat cattgaggaa
    11701 aatggtcaac ttcgtatcaa ggttgaagga aaagacgata tcatcgcaag caaagctctt
    11761 ctttcaattg gtcgtatgcc agaccttgaa ggtattggag aggttgagtt tgaattggat
    11821 cgtggttgta tcaaggtcaa cgaatacatg gaaacttcag ttccaggcat ttatgcacca
    11881 ggtgacatca acggtactaa gatgttggct cacgcagctt tccgcatggg tgaagtttcc
    11941 gctgaaaatg cccttaaagg aaatcatgca gttgccaaat tgaatttgac tcctgcagcc
    12001 atctacactc tccctgaagt agcagcagta ggtttgacag aagaacaagc ccgtgagaaa
    12061 tacgatgttg ccatcggtaa gtttaacttt gctgctaacg gtcgtgctat tgcatctgac
    12121 gctgctcaag gtttcgtaaa agttatcact gataagaaat acggagaaat ccttggtgta
    12181 cacattattg gtcctgcagc cgcagaatta ataaacgaag catcaagcat catcgaaatg
    12241 gaaatcactg ttgaggaaat gctgaagacc atccacgggc acccaactta ctctgaagtg
    12301 atgtacgaag cgtttgcaga tgttctagga atggccatcc attcacctaa gaaaaaataa
    12361 aacaaagata gattagactg gaaggttatt tccagtttct atcatataaa gtaaagggat
    12421 atcatgaaat acattatcaa tcattcaaat gacactgctt ttaatattgc cttggaagaa
    12481 tacgccttta aacacctttt ggatgaggat caaatcttcc tactttggat taacaagcca
    12541 tctatcattg ttggtcgtca ccagaacact atcgaagaaa tcaaccgtga ttatgttcgc
    12601 gaaaatggta ttgaggtagt tcgccgtatt agtggtggtg gagctgttta ccacgattta
    12661 aataacctca actacacgat catctccaaa gaagatgaaa ataaggcatt tgacttcaag
    12721 agcttctcaa ctccggttat caataccctg gctcaacttg gggttaaagc tgagttcaca
    12781 ggtcgtaatg accttgagat tgatggtaag aagttctgtg gcaatgccca agcctatatc
    12841 aacggccgta tcatgcacca cggttgcttg ctctttgacg ttgatttgtc agtcctcgca
    12901 aatgccctta aggtttcaaa agataaattt gaatcaaaag gtgtgaaatc cgtccgtgcc
    12961 cgtgtaacca atattatcaa tgaattacca aaaaaaatca cagtcgaaaa attccgtgat
    13021 ttactcttgg aatacatgaa aaaagagtac ccagagatga ctgaatacgt cttttcagaa
    13081 gaagaattgg ccgaaatcaa tcgcatcaag gatactaagt ttggaacttg ggactggaac
    13141 tatggtaaat cacctgaatt taacgtccgt cgtggaacca aattcactag tggtaaggtt
    13201 gaagtctttg ctaacgttac tgaatcaaaa atccaagaca tcaagattta tggtgacttc
    13261 tttggtattg aagacgttgc tgcagtagaa gatgtccttc gtggggtgaa atacgaacgc
    13321 gaagatgttc ttaaggcgct aaaaaccatt gatatcacac gctacttcgc tggtattagc
    13381 cgtgaagaaa tcgctgaagc ggtagttgga taaatcaaaa agaagttggc caactaacca
    13441 acttcttttt ttgatattta tttacataat ttaaaatacg taaaatcata aactatccag
    13501 agcattcttt tgttcatcat taacaatatg ggtatagagg tcagtgactt gtgtgctggc
    13561 atgtcctagt tggtgactga ctaaaacttg tgatttagta gcatcataga gcctagttgc
    13621 tagtgtatgg cgcagtttat ggggtgttac acgtacttta aaatcctctg agtatttagc
    13681 aaccattttc tcaacgctag aagcatcgat acgattagga acacctctgt agagagttaa
    13741 aaaaagggct gtatctgttt tttccgtttt atagcgttga ttccgaatgg ccagataatt
    13801 ctctaaataa ggtttagcaa aagcagcgac attgactgag tcacgtttgc caccttttcg
    13861 agtaacatca ataaccatca tttttagatt gagatctctt agatctagat taatagcttc
    13921 agataagcga acaccagatg ccaagagaag ggcaataatg gctaaatctc gttctttatt
    13981 tttgttgaat gatgagagag ctcgatttga aagctgttgt gggtgctctt gatcgatata
    14041 agttagaaaa ccttctgttt catcacctag aaagagtttt tgcttgatat tttcagctct
    14101 ggcagcaagg gtttctttct ttttcttggt tgaaactttt ttcattacat tacgatagaa
    14161 ataaggttcc ccctgatcgt tttcaacctc ctcggttaga tacttgtaaa gactagaaag
    14221 tgctgataag gttcgattga tagttgtctg tgaaacacct tgttttgttg tattagcatt
    14281 cagcaaggga cgttcacgta gataaaggat aaaggattcc atgtctttct tagacatatt
    14341 ttccaaaact gataaaggaa tatcggatat tttatcagcg tttgaaatac cagactccaa
    14401 aacccagctg aaaaatcggt catattcctt aaggtattcg tacagggttg taaaactgta
    14461 gggcacagcc agtttagatt ggtagtattc cagaacatac cagggcatga gttgttttag
    14521 tttgttgatt cgttccagta aaatctcacg tttcatgtat tttctccata agtaagtata
    14581 ctagtagtat agcatagact tgtatatttt tcaagaaaat tatagttttt cagaaagatg
    14641 ttataggagt ttttcaaagt gataaaaaga cttagaccta caaacaaaac agaataagga
    14701 aaataatgaa aatctcaccc actaaacttc tgttaatact acataactga agagctatat
    14761 aaggagctat gagatacaaa acacattgta taatagattg aaactagaat agtacatctg
    14821 gacttctaaa acattgctag aaattgattt gattgtcctg tttgttttat cctatttcta
    14881 tttcatttca ctataattac tattgttttc tttttcatga ttttaatctt actgtacaga
    14941 tttgatacag taaactcctt tctagct
//
LOCUS       DAVIME010000052        14926 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVIME010000052 DAVIME010000000
VERSION     DAVIME010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.052"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            1..455
                     /locus_tag="VV588_001772"
                     /pseudo
     CDS             1..455
                     /locus_tag="VV588_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            646..2937
                     /gene="pcrA"
                     /locus_tag="VV588_001773"
     CDS             646..2937
                     /gene="pcrA"
                     /locus_tag="VV588_001773"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU7084066.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSISDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2980..3660
                     /gene="radC"
                     /locus_tag="VV588_001774"
     CDS             2980..3660
                     /gene="radC"
                     /locus_tag="VV588_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU7084067.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3657..4346)
                     /locus_tag="VV588_001775"
     CDS             complement(3657..4346)
                     /locus_tag="VV588_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU7084068.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQNSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4364..5005)
                     /locus_tag="VV588_001776"
     CDS             complement(4364..5005)
                     /locus_tag="VV588_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU7084069.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTTILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(5088..5303)
                     /locus_tag="VV588_001777"
     CDS             complement(5088..5303)
                     /locus_tag="VV588_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU7084070.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5311..5658)
                     /locus_tag="VV588_001778"
     CDS             complement(5311..5658)
                     /locus_tag="VV588_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU7084071.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5663..6778)
                     /locus_tag="VV588_001779"
     CDS             complement(5663..6778)
                     /locus_tag="VV588_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU7084072.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPKNQEITAQQIQKALRDDTILVSTMFVNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6788..7747)
                     /locus_tag="VV588_001780"
     CDS             complement(6788..7747)
                     /locus_tag="VV588_001780"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU7084073.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7860..8429)
                     /locus_tag="VV588_001781"
     CDS             complement(7860..8429)
                     /locus_tag="VV588_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU7084074.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKRVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDVENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8557..9228
                     /locus_tag="VV588_001782"
     CDS             8557..9228
                     /locus_tag="VV588_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU7084075.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            9212..10030
                     /locus_tag="VV588_001783"
     CDS             9212..10030
                     /locus_tag="VV588_001783"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU7084076.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            10027..10923
                     /locus_tag="VV588_001784"
     CDS             10027..10923
                     /locus_tag="VV588_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU7084077.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10967..11941
                     /gene="pta"
                     /locus_tag="VV588_001785"
     CDS             10967..11941
                     /gene="pta"
                     /locus_tag="VV588_001785"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU7084078.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(12282..12581)
                     /locus_tag="VV588_001786"
     CDS             complement(12282..12581)
                     /locus_tag="VV588_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU7084079.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVISIDFNPAVIDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            12983..13687
                     /locus_tag="VV588_001787"
     CDS             12983..13687
                     /locus_tag="VV588_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU7084080.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     misc_feature    13746..13833
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            13869..14183
                     /gene="rplU"
                     /locus_tag="VV588_001788"
     CDS             13869..14183
                     /gene="rplU"
                     /locus_tag="VV588_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU7084081.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            14199..14543
                     /locus_tag="VV588_001789"
     CDS             14199..14543
                     /locus_tag="VV588_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU7084082.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            14560..14853
                     /gene="rpmA"
                     /locus_tag="VV588_001790"
     CDS             14560..14853
                     /gene="rpmA"
                     /locus_tag="VV588_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU7084083.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
BASE COUNT         4408 a         2795 c         3180 g         4543 t
ORIGIN      
        1 agtaaaaatc aatcgcccta aaaaaacaat tagcgaatga ttctggtaaa aagaaatgcc
       61 acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatca
      121 ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag
      181 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
      241 aaactccacg taaatccagc aaattcaagc cgctaacagt tgaagataaa acctataacc
      301 atgcgctatc taaggagaga agcaaggttg agaacatctt tgccaaagta gaaacgttta
      361 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt tggattacga atgaatttga
      421 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct attgaggtat
      481 tgagctagtt tatgaaaaaa ttgggtgaaa agtcgagtgt tttagaaacc cacagtgtag
      541 tattctagtt tcaatccact atattttgct actccccgta aagtttctat tttccctgat
      601 ttctgatata atagaaatat tgacttcaag agtaaggaag agaagatgaa cgcattatta
      661 aatggaatga atgaccgtca ggctgaggcg gtgcaaacga cagaaggtcc cttgctaatc
      721 atggcaggag ctggttctgg aaagactcgt gttttaaccc accgtatcgc ttatttgatt
      781 gatgaaaagc tggtcaatcc ttggaatatc ttggccatta cctttaccaa caaggctgcg
      841 cgtgagatga aagagcgtgc ttatagcctc aatccagcta ctcaggactg tctgattgcg
      901 accttccact ccatgtgtgt gcgtattttg cgtcgcgatg cggaccatat tggctacaat
      961 cgtaatttta caattgtgga tcctggtgaa cagcgaacgc tcatgaaacg tattctcaaa
     1021 cagttgaact tggatcctaa aaaatggaat gaacgaacta ttttggggac catttccaat
     1081 gctaagaatg atttgattga tgatgttgct tatgctgccc aagctggcga tatgtatacg
     1141 caaattgtgg cccagtgtta tacaacctat caaaaagaac ttcgtcagtc tgaatccgtt
     1201 gactttgatg atttgattat gctgaccttg cgtctctttg atcaaaatcc tgatgttttg
     1261 acctactacc agcaaaaatt ccaatacatc cacgttgatg agtaccaaga taccaaccac
     1321 gctcagtacc aattggtcaa actcttggct tcccgtttta aaaatatctg tgtggttggg
     1381 gatgcggacc agtctatcta cggttggcgt ggtgctgata tgcagaatat cttggacttt
     1441 gaaaaggatt accccaaagc caaggttgtt ttgttggagg aaaattaccg ctcaaccaaa
     1501 accattctcc aagcggccaa cgaggttatt aaaaataata aaaatcgccg tcctaaaaat
     1561 ctctggactc aaaacgctga tggggagcaa atcgtttact atcgtgccga tgatgagctg
     1621 gatgaggctg tatttgtagc cagaaccatc gatgaactta gtcgcagtca aaacttcctt
     1681 cataaggatt ttgcagttct ctatcggact aatgcccagt cccgtacaat tgaggaagcc
     1741 ctgctcaagt ctaacattcc ttataccatg gttggtggaa ccaaattcta cagccgtaag
     1801 gaaattcgcg atattattgc ttatctcaac cttattgcta atttgagtga caatattagt
     1861 tttgagcgta ttatcaacga gcctaaacgt ggaattggtc taggtacagt tgagaaaatc
     1921 cgtgattttg caaatttgca aaatatgtct atgctggatg cttctgctaa tattatgttg
     1981 tctggtatca agggtaaggc agcccaatct atctgggatt ttgccaatat gatgcttgat
     2041 ttgcgggagc agctagacca cttaagcatt acagagttgg ttgagtccgt cctagaaaaa
     2101 acaggttatg tcgatattct taacgcccaa gcgactttag aaagcaaggc acgggttgaa
     2161 aatatcgaag agtttctttc tgttacgaag aactttgatg acaccacgga tgtgacagaa
     2221 gaggaaactg gtctggacaa actgagtcgt ttcttaaatg acttggcttt gattgccgac
     2281 acagattcag gtagtcagga gacatcagaa gtgaccttga tgaccctgca tgctgccaaa
     2341 ggtctcgaat ttccagttgt ctttttgatt gggatggaag aaaatgtctt tccacttagt
     2401 cgtgcgactg aagattcaga tgaattagaa gaagagcgcc gtctagccta tgtaggtatc
     2461 acgcgtgcag agaaaattct ctatctgacc aatgccaact cacgcttgct ttttggtcgt
     2521 accaattata accgtccgac tcgttttatt aacgaaatca gttcagactt gcttgagtat
     2581 caaggtctgg ctcgtcctgc aaatacaagc tttaaggcat catatagcag tggtagtatt
     2641 tcctttggtc aaggtatgag tttggctcag gctcttcaag accgtaaacg cggtgctgcc
     2701 ccaaaatcaa tccagtcaag cggtcttcca tttggtcaat ttacagctgg cgcaaaacca
     2761 gcatctagcg aggcaaattg gtccattagt gatattgctc tccacaagaa atggggagag
     2821 ggaaccgttc tggaagtttc aggtagcggt gctaggcagg aattgaaaat caatttccca
     2881 gaagtaggtt tgaaaaaact tttagccagt gtggctccaa ttgagaaaaa aatctaattt
     2941 tccatccttc tcacgaataa taaagtgagg aggattttta tgtacagtat ttcattccaa
     3001 gaagattcac tattaccaag agaaaggctg gccaaggaag gagttgaagc gcttagtaac
     3061 caagagttgc tagctatttt actcaggaca ggaacacgtc aagctagcgt ttttgaaatt
     3121 gcccaaaaag tcttgaacaa tctttcaagc ctaacggatt tgaaaaaaat gaccctgcag
     3181 gaattgcaga gtttgtctgg tattgggcgt gttaaggcca tagaattaca agctatgatt
     3241 gaactggggc atcgtattca caaacacgag actcttgaaa tggaaagtat tctcagcagt
     3301 caaaagttgg ccaagaagat gcagcaggaa ttaggggata aaaaacaaga gcacctggtg
     3361 gcactctatc tcaatactca aaatcaaatc atccatcagc agaccatttt tatcgggtct
     3421 gtaactcgta gtatcgctga accgcgagag attcttcact atgcaatcaa gcatatggcg
     3481 acttctctta tcttggtcca caatcatcct tcaggagcgg tagcgcctag ccaaaatgat
     3541 gatcatgtca ctaaacttgt taaagaagcc tgcgaattga tggggattgt tctcttggac
     3601 catttgattg tctctcattc taattacttt agttatcgtg aaaagacaga tttaatctaa
     3661 agttcattaa cgacatagtc aaagagtttt ttatctttgg gacgattttc aaaaagaagt
     3721 tctggatgcc attggacacc gagaaaggcg acatcatccg tactcatgac agcctcaatg
     3781 ataccatctt taggatcatg agccacaact tttaaatttg gtgctaagtc cttgatgctc
     3841 tggtggtgga aggagttgat atgagagatt tctccataga tttcttggag aacggtatct
     3901 ggttctgtta ccaagcgttg agttgtgtac tcaacagaag aattctgcca atggtcttcg
     3961 atatcttggt acaaagttcc acccatggca acgttaaaga gttgggtacc acggcagaca
     4021 gagaaaatgg gctttttctg tttaatagct tccttgatga gggccagttc gaagatatct
     4081 ctttgaaggt gatagtcatc gctatcaatg gttttgggtt cgccataaaa ttttggatcg
     4141 acattttgcc cacctgtcaa gatgagcttg tcaatcaaac tgatatagtg gcaggccatt
     4201 tcttgatcac caatcggtag gatgatggga atccctccag catctttaac gccttcaaca
     4261 aagccttttg ctgcgtagct catcatgatg tcatcatctg gatgagtttt ttcgtttcct
     4321 gtaatcccaa taactggttt tttcataaaa tgattttcgc tttctaatcc tcttttcgca
     4381 tgaagtagag gagggtttgg agttcacttg tcaaatcgac atactgaacg accacgtctt
     4441 ttggtaaatg cagatggact ggtgaaaaac tgagaattcc tttcacacca gcatcaacca
     4501 agagattagc aacctcttgt gacttgacgc tgggaacagt taggatagta gtcttcacat
     4561 cagcatcctt gattttatcc ttgatctgag aaatcccgta aatgggaatc ccgtcaggag
     4621 tttgggtacc gacttcagga tggtcgtcta ggtcaaaggc catgataatc ttcatcttgt
     4681 tacgttcgtg gaagcggtag tggagaaggg catggcccat atttccaata ccaaccagca
     4741 tgacattggt aatagagttg tcattgagca aatcggcaaa aaatgtcatt agttttttga
     4801 catcatagcc aaaaccacga cgaccaagtt caccaaaata ggaaaaatca cgacgtacgg
     4861 tcgctgaatc aataccgata gcctctgcaa tttgcttaga gttggcacgt tcaatctttt
     4921 ctgcatgaaa tctcttaaaa attcgatagt agagagagag tctttttgct gtagcttttg
     4981 gaatagcaaa ctgtttatct ttcacaaaat cacaaccttt ctattcttct attttataga
     5041 aacattgtga aaaaatcaac aaaaataaga aaaaactaag aaaaatctta gttttgatgt
     5101 aaaaaatctg catgagatag aaaacggtag aggtctccga ccagcccctg ataaactttt
     5161 ttgcccctaa aagtcagaga agtcacataa agtgtatctg gtaaggttac acatcctgac
     5221 aaagtcaaca tgagagcctc atgatcctca tacttgagag tacgctctac atgatagcag
     5281 tccttatagg tcagttcaaa cattttggct ctatctttcc gattttgtaa agacaccacg
     5341 ttctaccaag ctatccatga ggaagtagaa tttttcctga tgaatatggt ggtcttctga
     5401 tttgaaaata tcaactagac gaaggccaaa cttgtcagtg atattgattt tagcccctgt
     5461 aagttccttg ttaatgatga ttttgagttg gaagccttca ccgctgtttg gcactttttc
     5521 caaaaggcga gtcagttcat agttaccaac cttagtttca aaaaaggtgt tatctttgag
     5581 ggtgaatttt ttaacagaag ggctaagagt gtaatcgtaa cgacaatttt ttaactgaat
     5641 gattttttca aatgccatat ggctaacctc cgataatttc ttttaaggtt tttgcgaggg
     5701 tttgtaggtc ttcaacggta ttttgtggcg acaaactgat gcgaagggat tccttcaagc
     5761 gttctgaatt tgcgccatac atggcttcaa gaacatggct ggattggaca acgcctgcag
     5821 tacaggctga gccagtagag attgaaattc cagctaaatc tagccgaagg agtaagaggt
     5881 catttttctg accaggaaat ccaatattga gaacataagg gagatgatgt tttcctctat
     5941 tcaggtaata ctgaatgccc tccagctctg ccagaaaggc agtttctaga ttttgtacat
     6001 gttgaaaatg ttcttcttgt ttttctaggt cttcttttag ggctgcaacc atgcctacaa
     6061 tggcaggcag attttcagtt cctgcacgtt ttttctgttc ctggtctccg ccatgtagat
     6121 aggaatcaaa gtccatgcta gatgcgtaga gaaaaccgat tcccttagga ccatggaatt
     6181 tgtgggcaga agcagtgaga aaatcaatgc ccaattcttc tgaatgaatt gggattttac
     6241 caatagcctg aactgcatca acatgatagg cagcagggtg ttgcttgagt atttggccaa
     6301 tttcagcgat gggcagtagg tttcctgtct cattattgac aaacatggta gaaaccaaaa
     6361 tcgtatcgtc acgtaaagcc ttttgaattt gctgggctgt gatttcttga ttttttggct
     6421 ggataatggt tgcttcaaac ccaaagtgtt gaaccaagta atcaattgtt tcaaggacag
     6481 catggtgctc gatggcagtt gtgatgatat gttttccttg ttcttggtga cgaagacagt
     6541 agccaatgat ggtagtatta ttgccttcag tcccaccaga agtgaaaaag atatgttgag
     6601 gttttgtcct tagtaactgg gctagttcct gacgggcttc tcgtaagagt ttgccagctt
     6661 gacgaccatg accatgaata ctagaaggat ttccgtgggt ttcttgcata accttggtca
     6721 tagctgaaat agcaactgct gacataggag tcgttgcagc attgtccaaa taaatcaaag
     6781 aatcacctta tttcttttta ttgtaggcaa agagtgggct gactggtttt ctttcgtgaa
     6841 tacggacgat agcatcacca attaactcac tagcagtgat gtagcataca tttttaggag
     6901 ttttttcttt tgttgctact gaatcagtca caagaatttc tttaatatta gtattgtcaa
     6961 gaagctcagc agctccctcg acgaagagac cgtggctaga aacagcataa atttctgtag
     7021 ctccttcacg ttcaacgatt ttagaagctt cagagaaggt acgtcctgta tttaaaatat
     7081 catcaatcaa gatagctttc ttaccttcaa catcaccaat aatataacct tcgttacgag
     7141 ttgcatcgtc ttgagggtag tcgataatgg cgataggagc atcaagatat tcagccaggc
     7201 tacgcgcacg tttgacacct gaatttttag ggctaacgac aacaacatct gaaccaagca
     7261 atcctttatc gcagtaatgt tttgcgaata ggggaacagt gaaaagatta tccactggaa
     7321 tatcaaagaa accttgaacc tgaacggcat gcaaatcaag agtcaggata cgatcaactc
     7381 cagccttaac cagcatattg gcaactagtt ttgctgtaag tggctcacga ggacaagcaa
     7441 tgcggtcttg acgtgcatag ccaaaatatg gaaggacaac gttgatactg tgggcacttg
     7501 cacgcacaca agcatcgacc atgattaaca attccattag gtggttgttg acagggaaac
     7561 ttgttgattg gatgatgtaa acatcataac cacggacact ttcttcgata tttacttgga
     7621 tttctccgtc tgaaaattga cgtgatgata gttttccaag tgggacacca acagcttggg
     7681 caattttctg tgcaatctct tggttagagt tgagtgcgaa aagtttcatg ttttttctat
     7741 ctgacattat agaccgtcct ctgtaaactt tataaatcct agttatattt accttacata
     7801 tatgaactgg ggtttgtgta tttttatctt ttctatttta ccaaaaaatg gagattattt
     7861 cagctatttt tcatactttt gacaaatcga accaattttg aaggagcttt ttggtaggaa
     7921 atctgatttt tctctaaaaa ttgtcggaaa tcctgtttgc cttgctcatg attttccact
     7981 tcaagctcca attcgtaatc tgtcatatca aagtatcggc tctgatccag tgccatgaga
     8041 ccaatagctg ttttcatttc atagcgaagc gttgttagac aaccaagaac ctgccagttc
     8101 ttactttgga taccatgttt cgccaattca tccagtacta gcccttgagg aagttcttcc
     8161 ttactcagat agttctcaac atcttttagt tgcaattttt ggttgtattc catgtttcca
     8221 acactctgcg ggactttgag tgtcaactca gcccagtctt caaaggttcg aatgcgcata
     8281 gcgactctct tttctcgcag ttcaaaatca ggcgtgtcta tgtagtaatt tgtttgaaga
     8341 acaggagtga cacctgtgaa ctggtctttt agacgattgt attcatcttt tttcaatagt
     8401 gttttcaatt caatttctaa atgtttcatt tttcttacct ttttttatcg ttgaaagcgg
     8461 atttatggta taataagcat tgtatttatt gtatatgaat ctggagaaaa aatcaaagat
     8521 atttttgacg gataatatga gaacaaggga gaatatatga ccttagaatg ggaagaattt
     8581 ctagatcctt acattcaagc tgttggtgag ttaaagatta aacttcgtgg tattcgtaag
     8641 caatatcgta agcaaaataa gcattctcca attgagtttg tgaccggtcg agtcaagcca
     8701 attgagagca tcaaagaaaa aatggctcgt cgtggcatta cttatgcgac cttggaacac
     8761 gatttgcagg atattgctgg cttacgtgtg atggttcagt ttgtagatga cgtcaaggaa
     8821 gtagtggata ttttgcacaa gcgtcaggat atgcgaatca tacaggagcg agattacatt
     8881 actcatagaa aagcatcagg ctatcgttcc tatcatgtgg tagtagaata tacggttgat
     8941 accatcaatg gagctaagac tattttggca gaaattcaaa ttcgtacttt ggccatgaat
     9001 ttctgggcaa cgatagaaca ttctctcaac tacaagtacc aaggggattt cccagatgag
     9061 attaagaagc gactggaaat tacagctaga atcgcccatc agttggatga agaaatgggt
     9121 gaaattcgtg atgatatcca agaagctcag gcactttttg atcctttgag tagaaaatta
     9181 aatgacggtg taggaaacag tgacgataca gatgaagaat acaggtaaac gaattgatct
     9241 gatagccaat agaaaaccgc agagtcaaag ggttttgtat gaattgcgag atcgtttgaa
     9301 gagaaatcag tttatactca atgataccaa tccggatatt gtcatttcca ttggcgggga
     9361 tggtatgctc ttgtcggcct ttcataagta cgaaaatcag cttgacaagg tccgctttat
     9421 cggtcttcat actggacatt tgggcttcta tacagattat cgtgattttg agttggacaa
     9481 gctagtgact aatttgcagc tagatactgg ggcaagggtt tcttaccctg ttttgaatgt
     9541 gaaggtcttt cttgaaaatg gtgaagttaa gattttcaga gcactcaacg aagccagcat
     9601 ccgcaggtct gatcgaacca tggtggcaga tattgtaata aatggtgttc cctttgaacg
     9661 ttttcgtgga gacgggctaa cagtttcgac accgactggt agtactgcct ataacaagtc
     9721 tcttggcggt gctgttttac accctaccat tgaagctttg caattaacgg aaattgccag
     9781 ccttaataat cgtgtttatc gaacactggg ctcttccatt attgtgccta agaaggataa
     9841 gattgaactt attccaacaa gaaacgatta tcatactatt tcggttgaca atagcgttta
     9901 ttctttccgt aatattgagc gtattgagta tcaaatcgac catcataaga ttcactttgt
     9961 cgcgactcct agccatacca gtttctggaa ccgtgttaag gatgccttta tcggtgaggt
    10021 ggatgaatga ggtttgaatt tatcgcagat gaacatgtca aggttaagac ctttttaaaa
    10081 aagcacgagg tttctaaggg attgctggcc aagattaagt ttcgaggtgg agctattctg
    10141 gtcaataatc aaccgcaaaa tgcaacgtat ctattggacg ttggagacta cgttaccatt
    10201 tacattcccg ctgaggaagg ctttgaaacc ttggaggcta ttgagcatcc attagatatt
    10261 ctctatgagg atgaccactt tctagtcttg aataaaccct atggagtggc ttctattcct
    10321 agtgtcaatc actctaatac cattgccaat tttatcaagg gttactatgt caagcaaaat
    10381 tatgaaaatc agcaggttca cattgttacc agactagata gggacacttc tggcttgatg
    10441 ctctttgcca agcacggtta tgcccatgca cgattagaca agcagttgca gaagaaatct
    10501 atcgagaaac gctactttgc tttggttaag ggagatggac atttggagcc agaaggggaa
    10561 attattgctc cgattgcgcg tgatgaagat tccattatta ccagacgagt ggctaaaggc
    10621 ggaaagtatg cccatacttc atacaagatt gtagcttctt atggaaatat tcacttggtc
    10681 tatattcacc tgcacactgg tcgaacccat caaatccgag tccatttttc tcatatcggt
    10741 tttcctttgc tgggagatga tttgtatggt ggtagtctgg aagatggtat tcaacgtcag
    10801 gctctgcatt gccattacct atccttttat catccatttt tagagcaaga cttgcagtta
    10861 gaaagtccct tgccggatga tttcagtaac cttattaccc agttatcaac taatactcta
    10921 taaaaactgt ctcagagtat aattattatc ttaaaggaga aaactcatgg aagtttttga
    10981 aagtctcaaa gccaaccttg ttggtaaaaa tgctcgtatc gttctccctg aaggggaaga
    11041 gcctcgtatt cttcaagcaa caaaacgctt agtaaaagaa acagaagtga ttcctgtttt
    11101 gcttggaaat cctgaaaaaa ttaaaattta tcttgaaatt gaaggaatca tggatggtta
    11161 tgaggtcatc gaccctcaac attatcctca atttgaagaa atggtttctg ccttggtgga
    11221 gcgtcgcaag ggcaaaatga ctgaagaaga tgtacgcaag gttttggttg aagatgtcaa
    11281 ctactttggt gtgatgttgg tttacttggg cttggttgat ggaatggtgt caggagcgat
    11341 tcactcaaca gcttcaacag ttcgtccagc tctacaaatc atcaaaactc gtccaaatgt
    11401 aactcgtact tcaggagcct tcctcatggt tcgtggtacg gaacgttacc tatttggaga
    11461 ctgtgccatt aacatcaatc cagatgcaga agccttggct gaaattgcca tcaactcagc
    11521 aatcacagct aagatgtttg gcatcgaacc taaaattgcc atgttgagct attctactaa
    11581 aggttcaggg tttggtgaaa gcgttgataa ggtcgttgaa gcaactaaaa ttgctcacga
    11641 cttgcgtcct gaccttgaaa tcgatggtga gttgcaattt gatgcagcct ttgttcctga
    11701 aactgcagct ctgaaagctc ctggaagtac ggtagctggt caagcaaatg tcttcatctt
    11761 cccaggtatc gaggcaggaa atatcggtta caagatggct gaacgcctgg gtggctttgc
    11821 ggctgtagga cctgttttgc aaggtttaaa caagccagtt aatgatcttt ctcgtggatg
    11881 taatgcagat gatgtttaca agttgaccct catcacagca gctcaagcag ttcatcaata
    11941 gtgaaaacta taaagcgata tactatgcta tactgtagtt atgaaactat gtacgaaaag
    12001 cactgccatt aattcctgag aactaaatta ctgattggtg tcaaaaagga aaacttccaa
    12061 gcgatgatat cctgtttata cacgacctat agaaatctgt aatatgtatg tccgtaaaac
    12121 gataatttcc ctttttgatt ttaaatgagt atgaaaagag aatttttcat gagaaaacgc
    12181 ataatattaa gtgtcttgac acctgctatt atgcgttttt tataattttt gcacctttct
    12241 tagcctttgt tatcgacaag tattgttcta gctccttgtt tttagaatgg caatttccca
    12301 gcgaaagcac ccagtttttt cttagtagtt tcatcgattt gttcaagagc agagttgatg
    12361 gcttgaacgg tcatatcaga aagagtttca aggtcctctg ggtcaatgac agctggattg
    12421 aaatcaatgc tgataacttt cttatctcca gttaaggtcg cttggacaag atcttgagca
    12481 gatttgccaa caaattgcat agcagcaagt tcagcttggc tttgttccat ttgtttttga
    12541 agtttttgtg cttgacgcat catgttttgc atgttcatca taagatttct aaagttcctt
    12601 tcatctcaag gggataatcc ttgttgttaa caagtgcctg attttctctc ctaattgtta
    12661 ttagtagcat agccatcaag cccaagtatt gattttatta taccattttt ttaagacata
    12721 gtcttttatt ggtgagagtt atttatgtca aggagtgatt agaaataaat taaaataatg
    12781 atttttgcta agagggctct attctagttt catggaaatg attttactaa aggttcgtat
    12841 gctttgtttg caaacatgtt acatctatct atttttggat aaatagttgt ctattattat
    12901 ttttatgcta atagtaaaat ctaaatggta gcctacgatt ttttagaaag aaaatggtac
    12961 aatatttcta agagaaaata caatgggagg taaaatgagg ttattaccta taagaaaaat
    13021 atcacgtcag tctaaaaggt tagcactttt tttgacgttt tgtgctggat atgtggatgc
    13081 ttacactttt attgttcgcg ggaataccct tgtagctgga caaactggaa atgttgtctt
    13141 tctttcagta gaattaatta aaaataatgt ttcggatgtt agggacaagg ttctcacctt
    13201 gctagcgttt atgatgggag tctttttatt aacgatttat aaggaaaaat tgagaattgt
    13261 gaaaaaacct attctgtcct tgattccctt ggcaatctta tcaatcatta ttgcttttgt
    13321 gccgcaaact gtggataata tctatctagt gccgcccttg gccttctgta tgggactggt
    13381 gacaactgct tttggagaag tgtcgggtat tgcctataat aacgctttta tgacagggaa
    13441 tatcaaacgg accatgctgg cttttggaga ttatttccga accaagcaca ctcctttttt
    13501 gcgtgaagga ttcatatttg ttagcctgct tagtagtttt gtccttggcg ttgtcttttc
    13561 agcctatttg acgattttct atcatgaaaa gaccattctt ggtgttccta ttatgatgag
    13621 cgttttttac ctcagcatgc tttttgcctc ttggcagaaa aaagtaaaag aaaaagcttc
    13681 attttaggtg ttattacttg taagaaaata ggagatatgc tatacttgaa gagttgacta
    13741 tgcacgatcc tgtgcaaccg cacgaacatc gttgcttgat tattcaagtt taagtggttc
    13801 gtcccacgat gctaggcgag tcttcacaaa aaatcgggga aacccataaa aatcatagga
    13861 ggtgcataat gagcacatac gcaattatca aaactggcgg aaaacaagtt aaagttgaag
    13921 ttggtcaagc agtttacgtt gaaaaattga acgttgaagc tggtcaagaa gttactttta
    13981 acgaagttgt tcttgttggt ggtgaaaaca ctgttgtcgg aactccactt gttgctggag
    14041 ctactgtagt tggaactgtt gaaaaacaag gaaaacaaaa gaaagtggtt acttacaagt
    14101 acaaacctaa aaaaggtagc caccgtaaac aaggtcaccg tcaaccatat acaaaagttg
    14161 tcatcaacgc aatcaacgct taattttaag gagaacacat gatacaggca gtctttgaga
    14221 gagccgaaga tggcgagctg aggagtgcgg aaattactgg acacgccgag agtggcgaat
    14281 acggcttaga tgtcgtgtgt gcatcggttt ctacgcttgc cattaacttt atcaattcta
    14341 ttgagaaatt tgcaggctat gaaccaatcc tagaattaaa cgaagatgaa ggtggctatc
    14401 tgatggttga aataccaaaa gatcttcctt cacaccagag agaaatgacc cagttattct
    14461 ttgaatcatt tttcttaggt atggcaaact tatcggagaa ctcttctgag ttcgtccaaa
    14521 ccagagttat cacagaaaac taacacggag gaaaacatta tgttaaaaat gactcttaac
    14581 aacttgcaac ttttcgccca caaaaaaggt ggaggttcta catcaaacgg acgtgattca
    14641 caagcgaaac gtcttggagc taaagcagct gacggacaaa ctgtaacagg tggatcaatc
    14701 ctttaccgtc aacgtggtac acacatctat ccaggtgtaa acgttggtcg tggtggagac
    14761 gatactttgt tcgctaaagt tgaaggcgta gtacgctttg aacgtaaagg acgcgataaa
    14821 aaacaagttt ctgtttaccc aatcgctaaa taaaaaggtc cattgaacct tttatcccga
    14881 accttgaaat ataaaggtga ggaagctaga aacagcttaa aataag
//
LOCUS       DAVIME010000053        14067 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVIME010000053 DAVIME010000000
VERSION     DAVIME010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14067
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.053"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(145..333)
                     /gene="pneA2"
                     /locus_tag="VV588_001791"
     CDS             complement(145..333)
                     /gene="pneA2"
                     /locus_tag="VV588_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU7084084.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            complement(340..564)
                     /gene="pneA1"
                     /locus_tag="VV588_001792"
     CDS             complement(340..564)
                     /gene="pneA1"
                     /locus_tag="VV588_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU7084085.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKICISAAVSGIGGLVSYNNDCLG"
     gene            1029..1892
                     /locus_tag="VV588_001793"
     CDS             1029..1892
                     /locus_tag="VV588_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7084086.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEAKELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            2275..2895
                     /locus_tag="VV588_001794"
     CDS             2275..2895
                     /locus_tag="VV588_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084087.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2981..3424
                     /gene="tsaE"
                     /locus_tag="VV588_001795"
     CDS             2981..3424
                     /gene="tsaE"
                     /locus_tag="VV588_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU7084088.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            3414..3932
                     /locus_tag="VV588_001796"
     CDS             3414..3932
                     /locus_tag="VV588_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7084089.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQAGGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            3940..4956
                     /locus_tag="VV588_001797"
     CDS             3940..4956
                     /locus_tag="VV588_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU7084090.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            5041..6297
                     /locus_tag="VV588_001798"
     CDS             5041..6297
                     /locus_tag="VV588_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU7084091.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            6352..7518
                     /gene="recA"
                     /locus_tag="VV588_001799"
     CDS             6352..7518
                     /gene="recA"
                     /locus_tag="VV588_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU7084092.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            7825..9195
                     /locus_tag="VV588_001800"
     CDS             7825..9195
                     /locus_tag="VV588_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU7084093.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     YIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            9571..10527
                     /gene="lytA"
                     /locus_tag="VV588_001801"
     CDS             9571..10527
                     /gene="lytA"
                     /locus_tag="VV588_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU7084094.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            10905..11066
                     /locus_tag="VV588_001802"
     CDS             10905..11066
                     /locus_tag="VV588_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7084095.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            11053..11259
                     /locus_tag="VV588_001803"
     CDS             11053..11259
                     /locus_tag="VV588_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084096.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            11305..11658
                     /locus_tag="VV588_001804"
     CDS             11305..11658
                     /locus_tag="VV588_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084097.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKKCY"
     gene            11792..12217
                     /locus_tag="VV588_001805"
     CDS             11792..12217
                     /locus_tag="VV588_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084098.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVKEFSLEYMTTGDILVEAFKA"
     gene            12625..13615
                     /locus_tag="VV588_001806"
                     /pseudo
     CDS             12625..13615
                     /locus_tag="VV588_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13605..>14067
                     /locus_tag="VV588_001807"
     CDS             13605..>14067
                     /locus_tag="VV588_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084099.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYSLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
BASE COUNT         4482 a         2254 c         2950 g         4381 t
ORIGIN      
        1 tatgcacatt tttaatttta tatttcattt acttacctca aacctatacg acttactatt
       61 gttttaaaaa aaaaacctct ctcaaaatta ttagttacga gagaggaaaa taaagagcaa
      121 cttttatttt taaaattgaa tattttattt tttcttgttg tctttgccac aacgagtctg
      181 agctgacccc aaatatgatg caataaaact taatgtagca gaacatataa ttgttgatct
      241 agggtcagca ccatctgtgc caccataaac caattgcatt tcttcaagag ataattcttt
      301 caaactcttt ccgattacaa aatcattttt cattttaatt taccccaaac aatcattatt
      361 gtagctaact agccccccaa taccagaaac agctgcacta atgcatattt tcgagctagc
      421 tgcagctgat ttcaaaataa taggagtagg cgtccaacgt ggctctgcac catcagatgc
      481 accataaatt aaactcattt catcagcaga caatgatttt aaactttttc cacaaaattt
      541 ttcgtttgaa ttaaagttgg tcataagtaa taactcctcc ttataaaaag ttaaataagt
      601 tgctctatat ttttcgtttt ttcagataaa ttataattct ctcattctcg tgcaaaatat
      661 cgggttttaa tccgccttcc caacatcaag accattggac ttcttttgcg attgcactcg
      721 aatctccaat tgtttattct tctgaataaa ctgttggtaa ggaattgtat tactaaacat
      781 aaaaacacct agcaatgcaa atgtaactaa ttttttaatt ccacgttttt ttctcatgca
      841 atgaaacccc tttctttttc cttgttttta ttctaacaga tatattttat ttagtcaagt
      901 atttttatgt aatttttaac tttttttttt gtttattacc ataaagaatt atttattcct
      961 ttaacttgct attttgaact aaaaacttta taatgaaatt aagcaaatag gaaggtttat
     1021 tatctttaat gaatacactc gcagagaaat tcagattgaa aagaaaagag ttgagactct
     1081 cccaacaaac tcttgcagaa ggaatttgtg aacaaagtca gattagtaaa attgagagag
     1141 ggcatttcat tccctccgca gaccttttgt tcaaactctc tcaacgactt gaagtaccat
     1201 tagattattt ttttaatgaa caaattgaaa ttaaatctaa cctctctaat ttcaagcaat
     1261 tgtctgctcg actattagac gatagaaatt atgacgattt ggaatatatt tatagaatag
     1321 agattgaacg aagtactttt ctaacactag aagaccgaac ttatcttgaa tggattaaag
     1381 ctattattga cttttatcaa tatgacagta agtgtgaagc aatttcttca ttggaaaata
     1441 tattattaaa agtctcctca aatactctga tttatttaaa ggcgttgaat actctatcta
     1501 atttctattc cttagtgggt cgtgaacaag aatatgaggc aaactactct catttaatag
     1561 agttgtatca gacaaaaaat ttggaccatc aagagttttt atttggctac atcagagttc
     1621 gttacaacta cgctcactac ctagtatcaa aggaaaaata taatgaagcc atccaagaag
     1681 ctcttgagac gattgaactc tgtaaacaaa gacagacaag ctaccaactg gctcctctac
     1741 ttattcttgt aggaaatgct ggagccaaat ttctagacag agaacaagtc aaaaattatt
     1801 atatagaagc aaaagagtta tgtaagattt ataacaatcc tttaatgctg atgaagatag
     1861 aaaattattt gaaggaatta gatactgttt agttaatctt gacattatag tttttctgaa
     1921 acgttaaata acctgtaagg ctgatagtga aatgaatact atcagcctta tgattatgtg
     1981 actattagtt cgtctcgctc cgttaggtgc gagacaaaaa aaacacccgc tagacggatt
     2041 ttcatgattt caaatttata ttcttcgaaa atctcttcaa atcacgtcag ctctatctgc
     2101 aatctcaaaa cagtgttttg agcaacctgt ggctagctac ctagtttgat ctttgatttt
     2161 cattgagtat tagtctctag tgtttgttta gcgtcttaaa gagacatttg agaagattag
     2221 aaacagttct ctcttttctc ctagtataat gattggtagg aagggagaga gaagatgaaa
     2281 tcaatgagaa tcttattttt gttagcttta attcaaatca gtttgagtag ctgtttccta
     2341 tggaaggaat gcatcttgtc ctttaaacaa agtacagctt ttttcatcgg aagcatggtt
     2401 ttcgtttcag gaatctgtgc tggagtaaat tatctttata cccgtaagca agaagtccat
     2461 agtgtcctag ccagtaagaa gtcggtgaag cttttttaca gtatgttact cttaattaat
     2521 ttgttaggag ctgttcttgt tttgtcagat aacttgttca tcaaaaatac gctgcagcaa
     2581 gaattagttg actttttatt gccatccttc tttttcctat ttgggctaga tttgctgatt
     2641 tttttaccct tgaaaaaata cgtgcgcgat tttcttgcta tgctagacag aaaaaagaca
     2701 gtgttggtga ctattttagc aacacttctt ttcttaagaa atccaatgac cattgtctca
     2761 cttctgattt atattggact gggcttgttt tttgcagcct atcttgtccc aaattcggtt
     2821 aagaaggaag tttcctttta tggtcatatt ttccgagatc ttgtattggt cattgttacg
     2881 ctcattttct tttagagaaa gcctgttttt tatggatgtt atgatgataa gtttagtagg
     2941 aaaatagaca caaaagaaaa gtttttggta taataagagt atgtacacaa aaaatgaaga
     3001 agagttgcaa gccttagggg agcgtttggg ccatctatta gcaaagaatg atgttttaat
     3061 cttaactgga gaactgggtg caggtaaaac gacctttact aaaggacttg caaaaggatt
     3121 acagatttct caaatgatta aaagtcccac ctatactatc gtgagagagt atgaaggtcg
     3181 acttccactt tatcacctag atgtttatcg tattgaagga gatgctgatt ctatcgactt
     3241 ggatgagttt atctttggtg gcggcgtgac tgttattgag tggggaaatc tcttaggaga
     3301 tgccttgcca gatgcttatt tagaattgga aattctaaaa gaagcagatg gacgccgttt
     3361 aaattttcag gcaaagggtt tgcgtgctga gaaattgtta gaggagcttc aatatggagt
     3421 atgaattgct cattagggaa gcagagccca aagatgcagc tgaattagtg gcctttttaa
     3481 atcgtgtgag tttggagaca gactttacca gcctagacgg agatggtatt ctcttgacta
     3541 gtgaggagat ggaaatattc ctcaacaagc aagctagttc ggacaatcag ataaccttac
     3601 ttgcattctt aaatggcaaa attgctggta ttgtaaatat tacagctgat cagcgtaaga
     3661 gagtccgtca tattggagat ctcttcattg tgattggaaa aagatattgg aataatggct
     3721 tgggaagttt gttgctagaa gaagcgatag agtgggcaca agcaggtggc attctgcgtc
     3781 gtctccaact gactgtccaa actcgtaatc aagcagcagt ccatctttat caaaagcatg
     3841 gctttgtcat tgaaggtagc caagagcgtg gggcatatat agaagaaggg aaatttatcg
     3901 atgtttactt gatgggtaaa ctgataggtt agtagaaata tggttaaaaa aattattgga
     3961 atggtgctag ctttactttc tgtaactgta gtaggagtag gtgtttttgc ttatactatt
     4021 tatcaacaag ggacagaaac cttagctaaa acctataaaa aaatcggcga agaaaccaag
     4081 gttattgaag cgactgaacc tctaaccatt ctgttaatgg gagtggacac cggaaatgct
     4141 gaacgaactg aaacttgggt cggtagaagt gatagcatga tcttgatgac agtgaatcct
     4201 aaaacgaaaa aaacaacaat gatgagttta gagcgggata ttctgacgcg cattgaatca
     4261 gggaatggtc aggctcatga agcgaaactg aactcagcat atgcagatgg tggagcagag
     4321 cttgctatag aaaccattca aaaaatgatg aatatccata ttgatcgcta tgtaatggtc
     4381 aatatgagag ggttgcaaaa actagtggat gcagtaggag gtattacagt caataatatc
     4441 ctaggtttcc caatttctat cagtgaccaa gaagaattta atactatttc tatcggtgtt
     4501 ggggagcaac atattggggg agaagaagcc ctagtctatg cacgaatgcg ttaccaagat
     4561 cctgaggggg attatggtcg tcaaaaacgt caacgtgaag ttattcaaaa agtcatggaa
     4621 aaagctctca gtttaaatag cgttggtcat tatcaagaga ttctaaaagc tttgagtgac
     4681 aatatgcaga ccaatattga tttgtctgca aaaagtatcc ctaacttgct aggctataaa
     4741 gattcattta aaaccattga aactcagcag ttgcagggtg aaggagagat acttcaaggt
     4801 gtttcttacc agattgtttc gagagcacat atgttggaaa tgcaaaatat actccgacgt
     4861 tctttgggac aagaagaagt tactcagctt gaaaccaatg cggttttatt tgaagattta
     4921 tttggcagag cacctgttgg tgatgaagat aattaacttt tgatacaaat aaaaaaatca
     4981 atcgtaggaa aattcctgcg attttttcaa aaaaatacga atagataggt aggaggaaac
     5041 atgaaagcag aaatcattgc tgttggaaca gagattttga caggacagat tgtcaacacc
     5101 aatgcccagt ttttgtcgga aaaactagct gagattgggg tagatgtata ttttcagacg
     5161 gctgtaggag acaatgaagt tcgtctcttg tctttgcttg agattgccag tcaacgtagc
     5221 agtctggtga ttttgacagg cggtttgggg ccaactgagg acgacctaac caaacaaacc
     5281 ctagctaaat ttttagggaa agcattagtc tttgatcctc aggctcagga gaagttggat
     5341 atcttttttg ccctgcgacc agactatgcc cgaacaccga ataacgaaag acaagctcaa
     5401 attgtagaag gagcgattcc actgccaaac gaaacaggac tggctgttgg aggaaaatta
     5461 gaagtagacg gagtgaccta tgtcgtcctt ccaggtccgc caagtgaatt gaaacccatg
     5521 gtcttaaacc aacttctacc caagttgatg acagggagca agctgtattc ccgagttctt
     5581 cgtttctttg ggattggcga gagccagttg gttacgattt tggctgattt aattgataat
     5641 cagatcgatc ctaccttggc cccttatgcc aagacaggag aagtcactct acgtctgtca
     5701 acaaaggcta gcagtcaaga agaggcgaat caagcgctgg atatcttgga aaatcaaatc
     5761 ttggactgcc agactttcga aggaatttct ttacgagact tttgctatgg ttatggggaa
     5821 gaaactagtt tagccagcat tgtggtagaa gaactgaaaa ggcaagggaa aaccatcgcg
     5881 gctgcagaga gtttgacggc aggtcttttc caagctaccg tggcgaattt ttctggagtt
     5941 tcaagtatat ttaagggtgg ttttgtgacc tatagcttgg aggaaaaatc aaggatgttg
     6001 gatattcctg ccaagaattt ggaagaacat ggtgtggtgt ctgaatttac agctcagaag
     6061 atggctgagc aggcacgaag caagacccag tctgattttg gaattagttt gaccggagtg
     6121 gcaggaccag atagcctaga aggacaccca gttgggacag tcttcatagg cttggcgcaa
     6181 gagcaaggaa ctgaggttat caaggttaat attggaggca gaagccgagc agatgtacgt
     6241 catattgcgg ttatgcatgc ctttaaccta gttcgcaagg ctttattaag tgactaactt
     6301 ttgatataat agtagatagg tctgaggatc attagaatgt aggagaatag aatggcgaaa
     6361 aaaccaaaaa aattagaaga aatttcaaaa aaatttgggg cagaacgtga aaaggccttg
     6421 aatgacgctc ttaaattgat tgagaaagac tttggtaaag gatcaatcat gcgtttgggt
     6481 gaacgtgcgg agcaaaaggt gcaagtgatg agctcaggtt ctttagctct tgacattgcc
     6541 cttggctcag gtggttatcc taagggacgt atcatcgaaa tctatggccc agagtcatct
     6601 ggtaagacaa cggttgccct tcatgcagtt gcacaagcgc aaaaagaagg tgggattgct
     6661 gcctttatcg atgcggaaca tgcccttgat ccagcttatg ctgcggccct tggtgtcaat
     6721 attgacgaat tgctcttgtc tcaaccagac tcaggagagc aaggtcttga gattgcggga
     6781 aaattgattg actcaggtgc agttgatctt gtcgtagtcg actcagttgc tgcccttgtt
     6841 cctcgtgcgg aaattgatgg agatatcgga gatagccatg ttggtttgca ggctcgtatg
     6901 atgagccagg ccatgcgtaa acttggcgcc tctatcaata aaaccaaaac aattgccatt
     6961 tttatcaacc aattgcgtga aaaagttgga gtgatgtttg gaaatccaga aacaacaccg
     7021 ggcggacgtg ctttgaaatt ctatgcttca gtccgcttgg atgttcgtgg taatacacaa
     7081 attaagggaa ctggtgacca aaaagaaacc aatgtcggta aagaaactaa gattaaggtt
     7141 gtaaaaaata aggtagctcc accgtttaag gaagccgtag ttgaaattat gtacggagaa
     7201 ggaatttcta agactggtga gcttttgaag attgcaagcg atttggatat tatcaaaaaa
     7261 gcaggggctt ggtattctta caaagatgaa aaaattgggc aaggttctga gaatgctaag
     7321 aaatacttgg cagagcaccc agaaatcttt gatgaaattg ataagcaagt ccgttctaaa
     7381 tttggcttga ttgatggaga agaagtttca gaacaagata ctgaaaacaa aaaagatgag
     7441 ccaaagaaag aagaagcagt gaatgaagaa gttccgcttg acttaggcga tgaacttgaa
     7501 atcgaaattg aagaataagc tgttaaagca gtggagaaat ccgctacttt ttcgattttt
     7561 gattcaagtt tttagattat atatagtaga ttgaaataag atatgaacaa ctttattagg
     7621 aaagtcaaat taatttctag aaatgtttta gcagctacag cgtactattc caaactcaac
     7681 caactataat agatcgaaac tagaatagta cacatctact tctaaaacat tgttaaaaat
     7741 cgatttgact gtccttattt cattccgcta tatataagtt tgctgtttct tgtcgctcct
     7801 ctggaaagct gatataatag ctttatgaat aaaaaacgaa cagtggacct gatacatggt
     7861 ccgattcttc cctcgctctt aagcttcacc tttccaatct tgttatcaaa tatttttcaa
     7921 cagctctata acactgctga tgtcttgatt gttggacgat ttcttggtca agaatccttg
     7981 gctgcagtag gagcgacgac agcgattttt gatctgattg taggttttac acttggtgtt
     8041 ggcaatggca tggggattgt cattgctcgt tattatgggg ctcggaattt cactaaaatc
     8101 aaggaagcag tagcagccac ctggatttta ggtgctcttt tgagcattct agttatgttg
     8161 ctgggctttc ttggcttgta tcctctcttg caatacttag atactcctgc agaaattctt
     8221 cctcaatctt atcaatatat ttctatgatt gtgacctgtg taggtgtcag ctttgcttat
     8281 aatctttttg caggcttgtt gcggtatatt ggtgacagtc tagcagccct gggatttctg
     8341 attttctctg ccttggttaa tgtggttctg gatctctatt ttattacgca attgcatctg
     8401 ggagttcaat ccgcaggact tgctaccatt atttcgcaag gtttatcagc ggttctctgc
     8461 ttttattata ttcgtaaaag tgtgccagaa ctcttgccac agtttaaaca tttcaaatgg
     8521 gacaaaagct tgtacgcgga tctcttggag caaggtttgg ctatgggctt gatgagttca
     8581 attgtatcta tcggcagtgt gattttacag ttttctgtta atacatttgg tgcagtgatt
     8641 attagtgccc agacggcagc tcgacgcatt atgacctttg cccttcttcc tatgaccgct
     8701 atttctgcat caatgacgac ctttgcttct cagaatctag gagctaagcg acctgaccgc
     8761 attgttcaag gtcttcgaat cggcagtcgt ttaagtatat cctgggcagt ttttgtttgt
     8821 attttcctct tttttgccag tccagccttg gtttccttct tggctagttc gacagatggt
     8881 tacttgatag aaaatggaag tctctatctg caaatcagtt cagcctttta tcccattttg
     8941 agcctcttgt tgatttatcg caattgcttg cagggcttgg ggcagaagat ccttcctcta
     9001 gtttctagct ttattgaact aatcggaaaa atcgtttttg tggttttgat tattccttgg
     9061 gcaggatata agggtgttat cctttgtgaa cctcttatct gggttgccat gacagttcaa
     9121 ctgtacttct cactattccg tcatcccttg ataaaagaag gaaaggcaat tttggcaacc
     9181 aaagtgcaat cctagttgga tttactgaat aaaatccatt tcctctagtg aacatcgaaa
     9241 aaacttgtgt tctcttcttc agtttggtgt tgaaaatagt ttaacagact tttgacttct
     9301 tttatatgat ataataaagt atagtattta tgaaaaggac atatagagac tgtaaaaata
     9361 tacttttgaa aagcttttta gtctggggtg ttattgtaga tagaatgcag accttgtcag
     9421 tcctatttac agtgtcaaaa tagtgcgttt tgaggttcta tctacaagcc taatcgtgac
     9481 taagattgtc ttctttgtaa ggtagaaata aaggagtttc tggttctgga ttgtaaaaaa
     9541 tgagttgttt taattgataa ggagtagaat atggaaatta atgtgagtaa attaagaaca
     9601 gatttgcctc aagtcggcgt gcaaccatat aggcaagtac acgcacactc aactgggaat
     9661 ccgcattcaa ccgtacagaa tgaagcggat tatcactggc ggaaagaccc agaattaggt
     9721 tttttctcgc acattgttgg gaacggttgc atcatgcagg taggacctgt tgataatggt
     9781 gcctgggacg ttgggggcgg ttggaatgct gagacctatg cagcggttga actgattgaa
     9841 agccattcaa ctaaagaaga gttcatgacg gactaccgtc tttatatcga actcttacgc
     9901 aatctagcag atgaagcagg tttgccgaaa acgcttgata cagggagttt agctggaatt
     9961 aaaacgcacg agtattgcac gaataaccaa ccaaacaacc actcagacca tgtggatcca
    10021 tacccttact tggcaaaatg gggcattagc cgtgagcagt ttaagtatga tattgagaac
    10081 ggcttgacga ttgaaacagg ctggcagaag aatgacactg gctactggta cgtacattca
    10141 gacggctctt atccaaaaga caagtttgag aaaatcaatg gcacttggta ctactttgac
    10201 agttcaggct atatgcttgc agaccgctgg aggaagcaca cagacggcaa ctggtactgg
    10261 ttcgacaact caggtgaaat ggctacaggc tggaagaaaa tcgctgataa gtggtactat
    10321 ttcaacgaag aaggtgccat gaagacaggc tgggtcaagt acaaggacac ttggtactac
    10381 ttagacgcta aagaaggcgc catggtatca aacgccttta tccagtcagc ggacggaaca
    10441 ggctggtact acctcaaacc agacggaaca ctggcagaca agccagaatt cacagtagag
    10501 ccagatggct tgattacagt aaaataataa tggaatgtct ttcaaatcag aacagcgcat
    10561 attattaggt cttgaaaaag cttaatagta tgcgttttct tgtggagata tttccttcaa
    10621 tttttgctac tatattaaac aaaaatcaaa aagcaaacta gaaagttatg ctcaaataaa
    10681 atctaaattt gacaatgtaa accgagtcgg atagctttaa gtactgtttt gaggttgaag
    10741 atacgatttt tgataggaac tcatcaaata ggtttaatat catcaatttt agatttttaa
    10801 gtagcatcaa taaattgctt ccttgttttg tcataatttt tttatttaaa aaattatgac
    10861 aagagtgtgc tattcttttt atgagaggtg tatgaatatg ataaatgtat gtgataaatg
    10921 tatgtgatgt tggaaaaaga ataaaagaac ttagaatatc ttcaaatctt actcaagata
    10981 agattgctga gtatttgtct ttgaatcaaa gcatgattgc caaaatggaa aaaggtgaaa
    11041 ggaatatcac gaatggattt aagtaataaa gctccaaatc ttagaaaaaa gttgggagct
    11101 gatggtgaat cgccgataga tatttttaaa ttggtacaaa agatagaaaa tttgacgctg
    11161 gtattttatg gactcggaaa gaatattagc ggagtctgtt ataaaggaac tcagttcagt
    11221 ctcattgcag tcaattcaga catgtcatta ggaaggtaaa gattttcttt agcacatgaa
    11281 ctgtatcatc tttattatga tgaggtgaag aagagttcag tcagtcttat cttgattggt
    11341 gaaggagatg aaactgaaag aaaagcggat cagtttgctt cttatttttt aattttccca
    11401 tcttcactgt ataggatggt tgaggaaatc agagaaaatg ccaatagaac tcatcttgaa
    11461 gtagaagata ttataaaatt gggtcagttt tatggtatca gtcataaagc tatgttatat
    11521 agattgagga atgatggata ccttgatgca gaagaaatta aaaatatgga tattagtgtt
    11581 atagagacag cttcaagatt aggctatgat acaagtttat atcgtccttt gtcagaaagt
    11641 aaaaagaaat gttattagga taatatatta atctaactga acaactttta gaaaataaca
    11701 gaatttcgca agggaagtat gaggaactgt tactagatgc tttcagatat gatattgtat
    11761 atgggctaga tgaagagggg ggagttgtcg tttgactagt cgtgtattta ttgatgcaga
    11821 ttgtatttca gtatttttat gggttggcac tgaacatctt ttagaaaagc tctatttggg
    11881 taaaattgtt attccacaag aggtgtatga tgaaatcaat atacctacaa ttccccattt
    11941 aaaatctagg atagatcagt tggtagctaa gggttcagct gagattgtga gcatagacat
    12001 tggaactgaa gaatacgcat tatatagaga tttaacaaga aatcatgata gtaacaagat
    12061 tattggtaag ggagaagcgg cttctatttc cttagcgaaa aagcataatg ggatattagg
    12121 aagtaataac ctaagagatg ttaaatcata tgtaaaagaa ttttctttag aatatatgac
    12181 aacaggagat atactggttg aagcgtttaa agcgtaattt attactgaac aagagggcaa
    12241 tcatatctgg aataatatgc ttaaaaagag aaggaaaatt ggtgcaaatt cattttcaga
    12301 ctatcttcgt ggaagtattc atcaaaatag acaaaaataa atttggataa atcgaactca
    12361 ctattcagga ggcatatgag caattcgaaa aagaaaagtg tcaaattgag cctataggag
    12421 tagaagtgaa atagtaagtc ctgcatagtg gatgagagaa aagttctcct tgaagttttc
    12481 ctgaactatc agtcgcatgt caaacgatat gtagggtaat gtgagagggg atagcgagta
    12541 gtttttggtt attttatcaa aaaacttata ttttattata ccgaatgata aaatataata
    12601 aaaatgatag aataaggaaa aaacatgaat gtcaaaaaga taatgtcaat ttttcaatcc
    12661 ttttatgttg atgtcagtat tgaggaactg actttaccaa tcagttttgt aaaaaagttt
    12721 gagtatactc aaatgacttt tcataaggaa tcatttttat tgattaaaga aaagagaagg
    12781 gggagtttga gttcatttgt tactcaggct cgcactatgg gtgataaagc caatatggat
    12841 gttgttttgg tgttttcgaa gttatcagac ggtgaaaaaa aagcaattac ttcaagctag
    12901 agttccgttt gtagacttta agggaaacct cttcttccct acattgggac tagtactgaa
    12961 tgcgaatgat actgaagtcc ctaaggaatt aatacctagc gaacaattaa cgtggattgc
    13021 ctttttattg acaaaaggtc aaaaagtagt agatgttgat ttgctttcac aagtcactgg
    13081 acttccaaac tcaacaattt ataggtgttt gaggactttt aaagctttat atttgttaaa
    13141 caagcaaaat aagctttaca catatacggt gtcaaagaaa gaattattct taaaatccgt
    13201 gtcatgttta tttaatccca tcaaaaaacg gattttattg ccagatggcg atataaagca
    13261 gataaaatct gtttctaacc ttctatatgg tggtgcttat gctttgtcgc attcaacttt
    13321 tttagctgaa acggatgaaa atattagcta tgtcatatgg cagagaaaat tcaatcagtt
    13381 acccttgcca ctttctcagc atattttaaa aggaaagatg ctagagatat ggaaatatcg
    13441 tccttttgta tctgagtttt ggaatgattt taaaaataat catgataaac aatttgtaga
    13501 tccgatttct ctttatttga ccttaaaaga tgatgatgac ccacgtatag aggaagagag
    13561 tgaagcacta gaaaatatga tattacagta tctgggagaa gatgatgcca gctaatacga
    13621 aagttatttt tcaagaaacg tttgcggatt ttcagaacta ttatgttctg attgggggaa
    13681 ctgctacctc tatcgtattg gattcgcaag gatttaaaag tcgcacaaca aaagattatg
    13741 atatggtcat cattgatgaa gtaaaaaata aggaatttta tactaccttg aatcattttt
    13801 tagaattggg agagtatcaa ggaagtcaga aagatgagaa agcgcagctt tttcgattta
    13861 caacaactaa tcctgagttt ccttctatga ttgaactatt tagtatctta ccagaatatt
    13921 cattaaagaa ggacggtcga gaaattccct tacattttga ccaagatgct agtttatcag
    13981 ccttattatt ggatgaagat tattataata tattggtgca tgaaaaagaa accattcagg
    14041 ggtattcggt attgagtaat tgtggtc
//
LOCUS       DAVIME010000054        13898 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVIME010000054 DAVIME010000000
VERSION     DAVIME010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13898
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.054"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            96..1274
                     /locus_tag="VV588_001808"
     CDS             96..1274
                     /locus_tag="VV588_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU7084100.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1502..1948)
                     /locus_tag="VV588_001809"
     CDS             complement(1502..1948)
                     /locus_tag="VV588_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7084101.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            2018..2677
                     /locus_tag="VV588_001810"
     CDS             2018..2677
                     /locus_tag="VV588_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU7084102.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2729..3880)
                     /locus_tag="VV588_001811"
     CDS             complement(2729..3880)
                     /locus_tag="VV588_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU7084103.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRASNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSICLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(3895..4626)
                     /locus_tag="VV588_001812"
     CDS             complement(3895..4626)
                     /locus_tag="VV588_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084104.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            4855..4956
                     /locus_tag="VV588_001813"
                     /pseudo
     CDS             4855..4956
                     /locus_tag="VV588_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(4928..5704)
                     /locus_tag="VV588_001814"
     CDS             complement(4928..5704)
                     /locus_tag="VV588_001814"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU7084105.1"
                     /translation="MPKTLTEKLNAIKVTGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIAGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(5697..6920)
                     /gene="trpB"
                     /locus_tag="VV588_001815"
     CDS             complement(5697..6920)
                     /gene="trpB"
                     /locus_tag="VV588_001815"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU7084106.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(6898..7497)
                     /locus_tag="VV588_001816"
     CDS             complement(6898..7497)
                     /locus_tag="VV588_001816"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU7084107.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVSLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(7484..8251)
                     /gene="trpC"
                     /locus_tag="VV588_001817"
     CDS             complement(7484..8251)
                     /gene="trpC"
                     /locus_tag="VV588_001817"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU7084108.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG"
     gene            complement(8248..9252)
                     /gene="trpD"
                     /locus_tag="VV588_001818"
     CDS             complement(8248..9252)
                     /gene="trpD"
                     /locus_tag="VV588_001818"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU7084109.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(9263..9829)
                     /locus_tag="VV588_001819"
     CDS             complement(9263..9829)
                     /locus_tag="VV588_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU7084110.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(9826..11187)
                     /gene="trpE"
                     /locus_tag="VV588_001820"
     CDS             complement(9826..11187)
                     /gene="trpE"
                     /locus_tag="VV588_001820"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU7084111.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYLYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKTKSMTRIGE
                     LRP"
     gene            complement(11559..11702)
                     /locus_tag="VV588_001821"
     CDS             complement(11559..11702)
                     /locus_tag="VV588_001821"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084112.1"
                     /translation="MDRTDEVSSKYCFEVVDRTDEVSNHTYGKATLTRFEELFEEYKD
                     VPR"
     gene            complement(11691..11771)
                     /locus_tag="VV588_001822"
                     /pseudo
     CDS             complement(11691..11771)
                     /locus_tag="VV588_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(12373..13374)
                     /locus_tag="VV588_001823"
     CDS             complement(12373..13374)
                     /locus_tag="VV588_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU7084113.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(13482..13745)
                     /locus_tag="VV588_001824"
     CDS             complement(13482..13745)
                     /locus_tag="VV588_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084114.1"
                     /translation="MVFAFHLPLDELITNVIFKEKINSMLKCYIDRLLYVFINPTHFT
                     EKVNLQFYGSFFSYEFICREVGNILKNKGVKCNLNFFEGKEYL"
BASE COUNT         4076 a         3075 c         2353 g         4394 t
ORIGIN      
        1 aagcaatgaa aagcttaaaa agattaacat ctacatttat ccatagcaaa aaatcatagg
       61 attttaagaa tctgacaact aggaagaaaa ctaatatgac cttatctaag aaacaattac
      121 aactaagagc taaaatactg gaaacagttt acacattagg tcccatttca cgaattgaaa
      181 tcgctactaa aacaggaata acacctgcaa caactagcag tatcacaaat gatctgatta
      241 aagaaaatat tctcttagaa cttggtgaag acgaacacga tacaagcgta gggagaaaaa
      301 aaatcctgct agacattcaa gctaaacgat tttactacat tggttgtgaa ctatctgaaa
      361 aacatttcac ttttgcttta ggagataatc taggaaatat cttaaaggaa gagaaagaaa
      421 ttgttactaa acagttaatc caagaaaagg gaaatcaact cattaaccag acactaaagc
      481 aattcttaaa taactgctct gattatgaaa tagaagcaat tggaatcgcg ctacctggtc
      541 gctatttaga taattataaa ataacaacaa acaatccttt atggcaacat atcgacttag
      601 aaatgattca atcccacttt gataagcctt tgtttttctc taacaatgtt aactgtatgg
      661 ctataggtaa acgcctattt agtcgccaac agaatgaccc taattttgct tattttcatt
      721 ttgctagagg tatgcactgt tcttatatct acgacggaaa catttatggg aaaggaaatc
      781 taatgattgg agaaataggg catacagttg tttcatctga gggagaagaa tgtagctgcg
      841 ggcgcaaggg atgcttacaa acttttgctg gagaatcttg gttaatcaaa aaatcaaaaa
      901 ttctatatca tcaatctccc tattctctac ttcctagttt agtcaaaaat gccgatgata
      961 ttgatatcca agttatttta accgcttatc aattaggtga cactggaata atcacactta
     1021 tccatcaagc cttactctat cttagtcaaa ccattttaaa tatcagtatg atgattgact
     1081 ctcaaaaaat ctacctacat agtcctttac taacaaatca acacatcatc caaaaactat
     1141 atagtgaaat gaactacaaa cccaaactgc tctataatcg cctacctgaa gtcattattg
     1201 aaccttacaa tgattttaca gccgcacact cagctattgc actttgtttg tatcatacaa
     1261 ttctacattc ttaattttct attacattta ataaataggc taaaaagagg gagtatatca
     1321 taaaaagcga ataaacctgt tttctgaaaa tcagaattct gttttgttcg ctttctttat
     1381 atttggaatt atactcctat ctcccctttt tcataatgta taataaaatg aaataataac
     1441 aggacgaatc gctcgggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt
     1501 actattctag tttcaatcta ctatattttc gtacaggtgc ttcaaccatt tgaacgattt
     1561 caaatccttc tttttggtaa agattctgag ctctttgatt tgcctcgaag acatttagag
     1621 aaatactatc tatatcttca ttttcaaagg ccaaactaac aaatttcctt aaagcctggc
     1681 tacctaagtc ttgctcctgt ttctgggggt tgataaaaaa tctcccgata tgaagattgc
     1741 tgtcttctag cctgattttc tggataagtc ccacaaactc ttgttcatca aagattgaaa
     1801 agactccttc caaggcttga agggtcagta gaaaaggaat ccttggtccc atccattgtt
     1861 cttgaaagga tttgcctagg gagttggacc actggcatac aaattgagcg ttttctatac
     1921 tcaccttttc ttcaaaacga attgtcatct tttcctcacc atcttatcta tgtttctcca
     1981 ttatactatt tctcccattt tttacgaata gataagtatg attgattttt atttttttct
     2041 cgtcgggagc attctcgctt cctttcttgg tttggtcatt gaccgttttc cagagcaatc
     2101 cattatcagt tcagccagtc actgcgattc ctgtcagact cgcttgcgtc ccttagattt
     2161 gattccgatt ctctcacagg tcttcaatcg ctttcgctgt cgctactgca aagttcgcta
     2221 tcctgtctgg tatgccctct ttgaattagt cttaggactc ctctttctgc tttactcttg
     2281 ggaattgctt tccttggggc aagtcgtcct aatcaccgct ggtttgacct tgggtatcta
     2341 cgactttcac catcaggaat atcccttact ggtctggatg actttccacc taatcctaat
     2401 agcttcctct ggctggaatc tggtcatggt ctccttcctt gctcttggaa ttttggctca
     2461 ttttatcgat atccgcatgg gcgcaggaga tttcctcttt ttagcttctt gtgctctcgt
     2521 ctttagcgta acggagttac tgatcttgat tcagtttgct tctgcgacgg gtatcctggc
     2581 ctttatcctg caaaagaaaa aggaaagact tcctttcgtg cctttcctct tacttgctac
     2641 ttgtttgatt atttttggta agctactgct tgtctgataa aatccaattt ctgccatatg
     2701 tccttcatga aattatttca cagttaaatt ataaattatt tcttttgtac aaagggatga
     2761 tgttatcaaa tcgatctgtt cttctatctt cttgatactg atcaaaaaat ttcatttcga
     2821 ctgaaaatat ttcgcttata aactgtaaac aaatactttg tttagacatt atagtcgcta
     2881 gactgactag atgattactc aaaacgacgt ccagaatact ctttactttg cttggttttt
     2941 taacaaaaat ttgatcatcc aaaggttcaa tcattttgta acctttttgc gcaatttgac
     3001 gataaaagta agaatgttgc tttggagtca ataatcctaa cttaaaagct cgatactcta
     3061 aagcctgtat cgaaacattc aaatccgact tcaataaaat ataactatca ggattgctgg
     3121 cacgcttgcc aaccctctct tcaaatttga ctaaaaactc ttcttttggc aataaaaaac
     3181 atgatgcaaa ataatttgct tcttgctcca aacgatcgcc atcttcattc atatccttat
     3241 atttatgtaa aagaatatgt cctagctcat gagctaagtc aaaatttcga cgtacagatg
     3301 atttattcgt tcccaacaca atataaggtc ttcccaattt tgaccatgcg ctataagcat
     3361 cagcttggcc attaattaat cgttccacga tatagatacc tgaacgttct aatttataaa
     3421 gcaaatcatg attatctttt gaaataccta atttttccct ggcataaaga gccaattcct
     3481 caatggattc tcccttatga taagattcac tcactacatt acttaggtca tgaattataa
     3541 tattaggtat aattacaaaa ctttcaaaat aatcaatcaa actatctacc ttatgtaaat
     3601 acatagtttg aatatctatt gttttccgtg ttgctaggtc tgcatttcta aaggcaatta
     3661 cagaagaatc aaatcgaatg ctctcttctt cctgttcaaa ataagttaaa tcaacatgaa
     3721 attggttggc caaatgcatt ttggttgata atttaggttt cgtttcgttg gactcaaact
     3781 gccaaatggc ttgttccgtt aaattaattc tctgagctaa ttctgctcta cttaaaccat
     3841 ttaacagccg taattctttc aatacccgac cattaaacat ttatatactc cttactactt
     3901 ttgaccttct tgtttttcta ttcttggaat aatttcaaaa tcttctgttt ccgataattc
     3961 tgaaaaatta ggaatatctt gatatttagc ttcttcgaaa tggtacgaac ttgattgaat
     4021 atactcagac aaatcttgaa tcaagtgtag ctgaccagtt cgtgcatcag gcataacaac
     4081 atctacagat ataatattgt tttctgagtc cgcctcataa gttaaaatca taaatttttc
     4141 gatattcgaa tttttagtag cttgttcaat ttcttgaatc atttcatcag aaactaactc
     4201 catctgaatt ggaaaggaat gactatcttc atcatttttg taggaagaat gttgattaag
     4261 ataaagtgta ttcatctgag cgtattcaaa taagtagcca ctcttatttt tttgtaccaa
     4321 aggaaattgg ttcgtaagtc gcttcttacc ctttataatt aacaatactt tcccatattt
     4381 ttctgtattt gtttcaaatt ctaaatatcc ccaagtctgt cctgctaatt gtaatttata
     4441 ctcaaacaaa tctgctgatg caaatgcagt atcaatatga ttaggtcgcg tccatgcata
     4501 accattcgac actatcattg tctctctttt ttctagacgt tcatctacat aatctttttg
     4561 ccctttcatc aaagtatcta caattttttg tgcctcaagc gaatcaaaga gatcctgatt
     4621 caacataatt cttcctcctc caaatacttt ttaatgaatt atatcatttt cttaaagaaa
     4681 ttactacaat aattatcttt ttcttaaagt tctgtgtcag agtaatttag aaaattatat
     4741 cttctatagt aaaatcaatt aaaaactgaa caaatttatt gggaaattca aatcgctttc
     4801 tgaaaatatt ttaggaaccg tagtgtaata ttccagattc aattcactat aaaactgacc
     4861 tttctcctgc aaaagaaaaa ggaaagactt cctttcgtgc ctttcctctt acttgctact
     4921 tgtttgatta tttttggtaa gctactgctt gtctgataaa atcctgaatc ggctctcctt
     4981 ggtggagagc ttttactatt tttgaaccga cgataacacc atctgacacc gcattgaagc
     5041 gttccagatc ggcttgacta gatacaccaa aacctgtcaa gactgggatg tcggccactt
     5101 gatgaagttg cgccaagtgc ttgtccaaat ctgcacggta attgcctgat ttccctgtca
     5161 ccccattgat ggcaacggca tagacgaatc cctccgcccc tgcaatcaac tctttctggc
     5221 gctcaattcc tgtggtcaag cttactaaag gaatcaaggc gatatctgta tctgccaaaa
     5281 atggttctac aaagttggca tgttcatgag gcaagtctgg gataatcaag cccttcacag
     5341 ctgtatcagc cagatctttg acaaagttct ccacaccgta ctgaaagagg gggttgaagt
     5401 aggtcatgat gaccagtgga atctctgttt caatggtttt caaggtttca actaaagcct
     5461 gggtagaggt cccgtgggct aaactgcgca agccagcttc ttcgataaca ggtccatctg
     5521 caacagggtc tgaaaaggga atacccactt caatagcaga gacacccaaa tcttctaaaa
     5581 agtgaattgt ttcagcaaga ccgtccaaac ctttctcgtg gtcaccagcc atgatatagg
     5641 gaacgaaaat tccttttcca gttactttta tagcattcaa tttttctgtt agtgtcttag
     5701 gcatgagctt ctcccttctt tgctgcatct gcttccaagc ggtctttgac ttgaaccaca
     5761 tccttgtccc cacgacctga taggcagaca atcatagact tttctggtcc aagttctttg
     5821 gccaatttca ccgcaaaggc gatagcatgg ctagattcca aggctgggat aatcccttcc
     5881 acacgagaca agagttggaa tccttccaag gcttcttcgt ctgtcacagg gacatagctg
     5941 gcacgtttaa tatcgtggta gtgagaatgc tctggaccga taccaggata gtccaaacct
     6001 gctgagatag agaaggcttc aagaatttga ccatgggcat cttggagcac atccatgagg
     6061 gaaccgtgaa ggacacctgg acgacccttg gtcaaggtag ctgcgtggtg ctccgtatcc
     6121 acaccaagtc cagccgcttc agctccatac atggctactg actcatcttc tacaaaggga
     6181 tggaagagac caatggcatt cgacccacca ccaacacagg ctactagggc atctggcaga
     6241 ttttgtcctg tcaagtcacg gtactgttgt ttagcctctc gaccaatgac actttggaag
     6301 tcacgaacaa tttctggaaa tggatgaggc cccaaggcag aaccaaggat atagtgggta
     6361 tcatctatat tagccaccca tgaacgaaga gctgcattga ccgcatcctt gagcacgcgc
     6421 gaaccatctg tcacggcctc gaccttagct cccaaaagct ccatacggaa gacattgagg
     6481 gcttggcgtt tgacatcttc ctcacccatg tagatggtac attccatgtt aaagagggcc
     6541 gcagcagttg cagttgccac accgtgctga ccagcaccag tttctgcgat aattttcttt
     6601 ttacccatac gtttggcaag ccaaacttgt cctaaggcat tgttaatctt gtgggctcct
     6661 gtatggttaa ggtcttcccg tttgagataa atcttggctc cgccgatatg ctgggtcaag
     6721 ttttttgcgt agtaaagggg agtttcacgt cccacatact ggcgcaaaag ttggtttaat
     6781 tcctcttgga aacttgggtc tgcctgactt tcacggtagg ccttctccaa ctccaaaact
     6841 gctgtcatca atgtttctgg gacaaaacgt ccgccgaatt ttccgtaaaa tccatcttta
     6901 tttggttcct gatatgccat gctttaccct ctctataaat cttctaatct tttcatgatc
     6961 tttttgtcca tctgtctcca ctccgctcga tacatctact gcatagggag taaaatgttg
     7021 aattgctttt actacattat cttcattaag gccacctgcg ataaagaagg gctgtgctag
     7081 tccagtcgta tccagttgac cccaatcaaa ggactgacca cttcctgcca caggggcatc
     7141 aaagagtaga taatctgcct gagaattggg gacatgccca tttccatcta cctgcacagc
     7201 ctgaatactg gcacaaggca aattctcaaa taaatcatct gccacctgac cgtgaacttg
     7261 aaccaagtcc aagctaactt tgtcaatcgc ttccagcagt tctacccgac ttggtgaaac
     7321 aaatactcca acctttttca catctgcagg aataagcttt gccaactcag ctgcctcttc
     7381 taaagtcacc tgtcttttac taggtgcgaa gacaaaaccg atatagtcgg ctcctgctga
     7441 aacggctgtt tccaccgctt ctttggtcga tagtccacaa atcttaacct ttgtcaatct
     7501 gcaactcctt gattctctgg accacatttt ctgcctgcat aagagctgtc cctaccaaaa
     7561 ttccgttaaa gtatggggct agtcgttccg catcctgccc tgtgaaaatg gcagattcag
     7621 aaatgtaata gcgaccttcc tcaaagtaag gggctaaatc tacactggtc tgcaagtcga
     7681 cctcaaaggt agtcaagttg cggttgttga ccccgataat ctcagcacca agtctgtggg
     7741 ctacctctag ttcagctaga ttgtgagtct ccactaagac ttccagacca agctctgtcg
     7801 cgtagtcgta aagttcctta agacgttctt ctgccaaggc tgccacaatg agcaagataa
     7861 ctgtcgcacc tgcattgcga gcgcggataa tttgcttttc atctatgata aagtctttgt
     7921 tgagcgtcgg aatctctacc tgactggaaa tttcccgtag ataatccaaa tgccctttaa
     7981 agaaaacctc atctgtcaac accgaaatca tcactgctcc gttttcttca taagtctggg
     8041 cctgttgcac aatatccaca tcgagattga tatctcccaa actagggcta gctttcttga
     8101 cctcagcgat tacctgcaag cggtcctgat gattcttcaa aaattctgcc aagcgatagg
     8161 tctggcgcag aggctggatt tgctccagct tcatctgctc cacctcacgc gccttctgct
     8221 ctaagattcg tgctaaaaat tcctgactca tttttggtac tcctgtaaca gtctgagttt
     8281 ttcaagggcc ttgcctctag caatcacttg acgggccaag gcaactcctt ccttgatgct
     8341 atcaatctta ccattagcat agaaaccaag accagcattc aagactgtcg tttccaagaa
     8401 tggacttgct tcgtttttca gaacgctaag caaaatttct gcattttcct gagcattccc
     8461 accacgaata tcttccatag catagccttc cattcccaaa tcctctggag taaagcttga
     8521 caagctgatt tcgccatttt caagaagtgc aatcttggtt gttccgttca agccagcttc
     8581 atccaaccct tctggtccag caaccacgat ggcacgtttg cgacccatat ttttcaaaac
     8641 ctgagctgta ctttctagga gttctggacg actaattcca agaagctgtg tttctaaagc
     8701 cattggatga atcagtggac cagtcaagtt cataatcgtt ggaattccca attccaaacg
     8761 agctggcatg atgtatttca tagctgggtg catattttta gcgaagagaa agacgattcc
     8821 agttttatca aagaccttac ctagttcagc tggtttgagg tcaagattga ttcccaaggc
     8881 ttcgaggaca tctgcggaac cagatttaga agaaatcgag cggttaccat gcttggccat
     8941 gtgaataccg ccaccagcca agacaaaggc tgcagttgtg gaaatattaa aactgaaaga
     9001 cttgtcccca cctgtaccac agttgtccat ggcatcatga atctcagttg gaatatgctg
     9061 ggcatgtcct ctcatgactt gggcaatggc tgtgcgttct tcaggtgttt cccccttcat
     9121 cttaagagct aagaggagag aagcaatctg cgcttcagtt acacgcccag ttacgatacg
     9181 ctcaatgaca tccgtcattt ccacacctga taaattttca aattttgcta gtttttcaat
     9241 aatctctttc atcctagttt cctcacttta caaccttctc gataaaattc cgaatagaag
     9301 acaagccgtc tggcgttcca atgctctctg gatggtactg gaagccataa atcggtaggt
     9361 ttttatgttg aatccccatg atggcttggt catcagtcga acgagctgtc acttcaaagt
     9421 cttctggcat ttcctcaatc aaaatactgt gataacgcat gaccgcacgt ccttcctcaa
     9481 taccttgata caaaacagat ggcgcttcaa agttgatatt gctctgtttc ccatgcatga
     9541 cttttggagc caaacctagc ttaccaccaa agacttctgc aatggcttgg tggcccaaac
     9601 aaatccctag aatcggcttc ttgcctgcaa aatcacgaat catgtcttcc atctttccag
     9661 catcaactgg ccaaccagga ccaggagaaa agaccagacc atctgctttt tcagcttctt
     9721 catacagctt ggaatcatca tttctcagaa cctgaacttc tgcaaaattc ccaatgtatt
     9781 gggccaagtt ataggtaaaa gaatcatagt tgtcaatcaa taaaatcatg gtcttagttc
     9841 tccaattcta gtcatagatt ttgttttgtt aatggtttct tggtattcgt tttgggcgat
     9901 agagtcgtag acaatccctg ccccagcctg cacataagct ctttgatttt tgagaatcat
     9961 ggttcggatg gcgatggcca aatccatatc acccgtcgca gacaagtagc cgattgctcc
    10021 tgcgtatacg ccccgttttt ctgtttccag ttcatagata cgtctcatag ctcgaatctt
    10081 tggcgctcca gaaacggttc cagcaggaag cgttgctttc aaggcatcca tagcagtgag
    10141 ttctggaagc aaacgcccct tgaccacgct ggtcaaatgc atgacgtagc ggaagagctc
    10201 cacttccata tacttagtga cttggacact ggtcgtttca gagatgcggc caatatcgtt
    10261 acgccccaag tctaccaaca ttcgatgttc tgctgtttcc ttctcatcag agaggaggtc
    10321 agtcgccaag gccttgtctt cttcatccgt agcccctctt ggtcgcgtcc ctgcaatcgg
    10381 attggttgtc acgatgccat ttttgacaga aaccaaactt tctggactgg ctccgatgat
    10441 ttgataatcc ccaaagtcat ataaatagag gtaattggat ggattggtca cgcggagatt
    10501 tctgtagaag tcaaatggat ttccagtaac ttctgctgag aagcgctgac tgagtacaca
    10561 ttggaacata tcgccattac gaatcaagtc gcgagcggtt tccaccattt cctcaaattt
    10621 atgtggagcg atatgcggtt tgaagtctaa cggagataga tccaagtctt caaattcatt
    10681 tggagcagga atgcgtaatt cctcaagcac ttggttcaag gatttttcca aggcctcttg
    10741 actgcgctca ctataaagtg catcctctat gacatggatt ttttccttct tgtggtcaaa
    10801 gaccatatag ctctcataga caaagaaatg catgtctggc gtcccaattg tatcctcagg
    10861 gatttgacca atttcttcat aaagcgaaat catatcgtaa cccacaaaac caatggctcc
    10921 accaccaaaa ggtagctctg agtggtgctg actcttatga atcacttcat aaaggaaatc
    10981 caagggatcc cgatcaatca cttgaccatt ttgatagaga actccatttt caaacttaat
    11041 ctcaaaaact ggattatagg ctaggataga aaaacgagct gtttccttgt ctctcggaat
    11101 actctctaaa ataaccttat gttgcccctt taagcgcata taagccaaga ttggtgataa
    11161 gacatctcca tgaatgattc gttccattgt aatttccctt tcagttctac ttctagtcag
    11221 tggtgactgt atgaaaaatc cccacgcaaa ataacttgcg tgaggacgaa attcgcggtg
    11281 ccacctcaat tataggattt ctcctatctc tcattcctgt ctcagatatc tcctgtaaca
    11341 ggctgtgcga taaagggcac tcccttgaga atgatgtttt cttctctcgt ttcagatgaa
    11401 cccaacttta cagctttctc tgcttgtttt cagcaaccac aagctctctg tgagagaaag
    11461 aactgtaatt tttccatcta ttatttttta gcttctagta gtctgcaatc gcagctaggt
    11521 ccttgcctcc acgaccagag acattgatga agagatgttc atctcggtac atctttatac
    11581 tcttcgaaca actcttcaaa ccgcgtcaac gtcgccttgc cgtaggtatg gttactgact
    11641 tcgtcagttc tatccacaac ctcaaaacag tattttgagc tgacttcgtc agttctatcc
    11701 acaacctcaa aacagtgttt tgagcaacct gcggctagtt tcctagttta ctctttgatt
    11761 ttcattgagt attactagct tttttcgtat tagtccagcc tttttgtttg cttttagtag
    11821 taggcaagga gctgtagata gaactcaagt tcatcaaagc gacttaaggc cctaataaaa
    11881 gataaaccaa acgacggata gaaaaaagcc cacacacaga atatacttcc gtgtgagggc
    11941 gttggtaacg cggtgccacc tcaattataa agggactatc cctttacatc tctgccttgt
    12001 ttaacaacaa gctgcactgt aaggtgtgcg caccgaattt tcattgtttc aaattcattt
    12061 tcaaaatcag cccactttca ctacttccaa ccacctattc acaatcacca caggctccct
    12121 gaagatcaaa aatagttact tttctgattt gttgaactta ttttaatact ttgttttttc
    12181 tttgtcaaga cttttttacg atttttttga aaatatcatt cgaatatgac catgtcttcc
    12241 ttagatcgaa catgaacatg tcccacttgt tagaaattgg atccaactca atagaaactg
    12301 aatggaggct aaacagaact tattttagaa cactccatct tttccactag gattttcaag
    12361 aattaaacaa tactagaaac tctgtctcct aacaaattta ggagaaactt caacagatgt
    12421 gacactttcc cctttaataa ttgctaaaac accttctatc atttctttag ccaatttaac
    12481 ataattggga gcaattgtag acaaagctgg agtataatac tgagaaatag gaatattatc
    12541 aaatccaatg atagaaatat catctggaat aagaattcct ttctcatagc acgcacgaat
    12601 caagccctga accttttcat ctcctgaaac aaaaataatg tccggataat tttgggtagt
    12661 caagtgctgc attgcataag aataaactga atcaattgta gataagccat aaatgacttt
    12721 taaatccata aagtaatttt tatcattcag aaaagaacgc acacctcttt cacgatcctt
    12781 attaacatgg gattctcctc ccataagcaa ccacatattt ttaaattttt cttcagttac
    12841 agctttcatc atatcataag tagcttgaaa attattatta gatacataga ctactccaga
    12901 cgtttgagat tcaccgaaaa caagaaaagg catatggttc ttctttaaat actgaattct
    12961 gatatcatct acactttcat aaaaaacaat aacaccatct actaggctac ctgtgcttga
    13021 tataattgaa ttactaattg tatcctcctc tccaaagtac tcaactatag cattaacacc
    13081 aaattcttta cacgtccgta acactttatc taacagcgta tgaaaccaaa ttaaaggaaa
    13141 agagtcgatt ttttttacag aaatcaatat atttatagct tcttttttag ttaaattttt
    13201 tgcatacgca tttggaatat acgacaattc ctctataact ttttgaatcg cttgataagt
    13261 ttcttcttta acatttactc caccattaat aactcgtgaa actgtttttg gagaaaaacc
    13321 tgataaacgt gcaatatcat aaatagttac ctttttccca tttatatttt tcatttcagt
    13381 cctccattac gaacattcta atattactat acaatattta atttttttta acaagagaat
    13441 ttagtaaatt atttaagatc cacaaattca caaaattaat tttacaaata ttctttccct
    13501 tcaaaaaagt ttaaattgca tttcacacct ttatttttaa gaatgtttcc aacttcacga
    13561 caaataaatt catatgagaa aaaactgcca taaaattgta gattaacttt ttcagtaaaa
    13621 tgtgtaggat ttataaaaac atataatagc ctgtcaatgt aacattttaa catagagtta
    13681 attttttctt taaagataac atttgttatc aactcatcaa gaggtaaatg aaaggcaaac
    13741 accatttcac aaatatcata aaaagaaata aatttgtata cttgtatcaa acaattatta
    13801 tcaaatattc tattttacct aaatcaaaat tgattttata atctttcata aaaacctctg
    13861 agcaaaaatc tactcaaaaa ttagatgatt aaaacatc
//
LOCUS       DAVIME010000055        13807 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVIME010000055 DAVIME010000000
VERSION     DAVIME010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.055"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            19..855
                     /locus_tag="VV588_001825"
     CDS             19..855
                     /locus_tag="VV588_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU7084115.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            891..1208
                     /locus_tag="VV588_001826"
     CDS             891..1208
                     /locus_tag="VV588_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU7084116.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            1208..2899
                     /locus_tag="VV588_001827"
     CDS             1208..2899
                     /locus_tag="VV588_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU7084117.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            3108..4514
                     /gene="lacG"
                     /locus_tag="VV588_001828"
     CDS             3108..4514
                     /gene="lacG"
                     /locus_tag="VV588_001828"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU7084118.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            4557..4814
                     /locus_tag="VV588_001829"
     CDS             4557..4814
                     /locus_tag="VV588_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU7084119.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEGWDTISFDSDFMPFQQS"
     gene            complement(5093..5854)
                     /locus_tag="VV588_001830"
     CDS             complement(5093..5854)
                     /locus_tag="VV588_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU7084120.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(6036..6998)
                     /gene="nrdF"
                     /locus_tag="VV588_001831"
     CDS             complement(6036..6998)
                     /gene="nrdF"
                     /locus_tag="VV588_001831"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU7084121.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(7186..9345)
                     /gene="nrdE"
                     /locus_tag="VV588_001832"
     CDS             complement(7186..9345)
                     /gene="nrdE"
                     /locus_tag="VV588_001832"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU7084122.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(9426..9644)
                     /gene="nrdH"
                     /locus_tag="VV588_001833"
     CDS             complement(9426..9644)
                     /gene="nrdH"
                     /locus_tag="VV588_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU7084123.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            9995..10258
                     /locus_tag="VV588_001834"
     CDS             9995..10258
                     /locus_tag="VV588_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU7084124.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            10264..11997
                     /gene="ptsP"
                     /locus_tag="VV588_001835"
     CDS             10264..11997
                     /gene="ptsP"
                     /locus_tag="VV588_001835"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU7084125.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            12251..>13807
                     /locus_tag="VV588_001836"
     CDS             12251..>13807
                     /locus_tag="VV588_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU7084126.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEEPSPQPAPNPQPAPSNPIDEKLVKE
                     AVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSD
                     REFYNKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVPSDKVKLVDDILAFLAP
                     IRHPERLGKPN"
BASE COUNT         4269 a         2563 c         2849 g         4126 t
ORIGIN      
        1 atataaaagg aggttgacat gtatcgaatt ctaaatccaa tgaatcacaa tgtctcgctt
       61 gtcagaaatg ataagggaga agaggtgatt ataattggta aggggattgc attcggaaaa
      121 aggaaggggg atttgattgc tgaaaatcag gttgagaaaa tctttcggat gaagaccgaa
      181 gagtccagag aaaactttat ggctcttctc aaagatgttc cgcttgattt tatcacagtg
      241 acctatgaaa tcattgataa gctatcaaag aaatatcatt atccgattca agagtatctc
      301 tatgtaacct tgacagatca tatttactgt tcttatcaag ctctaactca aggaaggtac
      361 aaggatagta atctgccgga tatttccgct aagtatcctg tcgcttttca aatcgcaaat
      421 gaagcttttg aaatttaccg tcagaagcta gcagatcatt ttcctgagga cgagattatt
      481 cggattgctt atcatttcat caatgccgaa ggtgaaaatg aagtggaact tgtggagtcg
      541 attgataaga ggaaagaaat tctcaggaat gttgaagaag tgctaaaggg ttatgcaatt
      601 caacgaacca aaaaaaataa tcatttctat gatcgcttta tgattcattt gaattatttc
      661 ttggattatt tagacagatc tagagatgat aaccaatcac ttctggatat ggaagatcat
      721 attaaacaat cctatccaaa agccttcgag attggttcca agatctatga tgtgattacg
      781 caacatacgg gtcttgattt gtataaaagt gaacgagttt atctagttct acatatccaa
      841 cgtttattgt cataaaaatt tatttaaaac tatataagga gaattctatc atgaatagag
      901 aagaagtaac attgttaggt tttgaaatcg tagcctatgc tggcgatgct cgttcaaaac
      961 tattggaagc cttgaaggct gctgaagctg gtgattttga aaaagcggac gctctggtag
     1021 aggaagctgg tagctgtatt gcagaggctc accacgcgca aacaagtcta ttgactaagg
     1081 aagcttctgg tgaggactta gcgtatagtg tgaccatgat gcatggccaa gaccacttga
     1141 tgacaactat cttgttaaag gatttgatgc accatttgat cgaactctat aagagaggag
     1201 ttaaataatg aacaaactaa ttgcatttat cgagaaagga aagcctttct ttgagaaact
     1261 atctcgtaat atctatcttc gtgctattcg tgatggtttc attgcaggta tgcctgttat
     1321 tctcttctca agtatcttta tcttgattgc ctttgtacca aactcatggg gctttaaatg
     1381 gtctgatgaa gttgtagcct ttctgatgaa accttatagc tattctatgg gtattctggc
     1441 tctcttggta gctggtacaa cagctaagtc attgactgac tcagtaaacc ggagcatgga
     1501 aaaaaccaat caaatcaact atatgtcaac gctgttagca gcgattgttg gtttgttgat
     1561 gttggcagct gatcctatcg aaagtggtct agctactgga ttcttgggga caaaaggttt
     1621 gctttcagcc ttccttgctg ccttcgttac tgtagccatc tataaggttt gtgttaagaa
     1681 caacgtcact attcgtatgc ctgacgaagt tccaccaaat atctcacaag tctttaaaga
     1741 tgtgattcca ttcactctat cagtggtttc tctttatgct cttgatttac tagctcgtca
     1801 ttttgttggt tctagtgtgg cagaatcaat cggtaaattc ttcgcaccac tcttctcagc
     1861 agcagacgga taccttggta ttaccattat ctttggtgcc tttgccttct tctggtttgt
     1921 gggtattcat ggtccatcta ttgttgaacc tgctatcgca gcgattacct atgcaaatgc
     1981 tgaagtcaac ttgaaccttc tccaacaagg tatgcatgct gataaaatcc ttacttcagg
     2041 aactcaaatg tttatcgtta ctatgggagg tactggtgcg acactggttg ttccattcat
     2101 gttcatgtgg ttaacaaaat caaaacgtaa ccgtgcaatc ggacgtgctt cagtagttcc
     2161 aactttcttt ggtgtaaatg aaccaatctt gtttggtgca ccacttgtat taaatccaat
     2221 cttcttcatt ccatttatct ttgctccaat cgcaaacgta tggattttca aattctttat
     2281 tgaaactctt ggaatgaact cattcactgc taatctacca tggacaactc cagctccact
     2341 aggtctagtt cttggaacta acttccaagt gctatcattc attcttgctg cccttctaat
     2401 cgtggttgac gttgtcattt actatccatt ccttaaggtc tatgatgaac aaattcttga
     2461 agaagaacgt tcaggtaagt ctaatgatga attgaaagaa aaagttgctg caaacttcaa
     2521 cactgcaaaa gcggatgcta ttcttgaaaa agcgggtgta gaagcagcac aaaatacaat
     2581 cactaaagaa acaaatgtcc tcgttctctg tgcaggtgga ggaacaagtg gtctccttgc
     2641 aaatgctttg aataaggcag cagcagaata caatgtccct gtgaaagcag cagcaggcgg
     2701 ctatggtgct caccgtgaaa tgttaccaga gtttgatctt gttatccttg cccctcaagt
     2761 tgcttcaaac tttgaagata tgaaggcaga aacagataag ctcggtatta aactagcgaa
     2821 aacagaaggc gctcaataca tcaaattaac tcgtgatgga aaaggtgctc ttgcattcgt
     2881 acaagcgcaa ttcgattaag gctagagact ctgaaatagt ctcctatcgt tacggaaatc
     2941 gctatggcga atttcctatt attaattcgt cggtaaaaag atatcgtttt tacctcctca
     3001 tgtcacaatt cggtgacttg gtacaagaag tgagatggag aaggatggct cactgactcc
     3061 tctcctctca cttttacttt atttaaatca agaaataggt gaaaaaaatg acaaaaacac
     3121 ttccaaaaga ctttattttt ggtggcgcaa cagctgccta tcaagcagaa ggtgctacac
     3181 atactgatgg taaaggacca gtagcgtggg ataaatatct tgaagataac tactggtaca
     3241 ctgcagaacc agccagtgat ttttacaatc gatatccagt tgacctcaag ctagcagaag
     3301 agtatggtgt caatggtatt cgaatttcta ttgcttggtc acgtattttc ccgactgatt
     3361 acggccaagt aaatgctaaa ggtgttgagt tttatcataa tttatttgca gagtgtcaca
     3421 aacgtcatgt tgagcctttt gtaactcttc atcactttga cacgccagaa gctctccact
     3481 caaatggaga cttcttaaac cgtgaaaata tcgaacattt tgtagactac gctgccttct
     3541 gttttgaaga atttccagaa gtaaactatt ggacaacctt taatgaaatt ggaccaatcg
     3601 gtgatggtca atatttggtt gggaaattcc ctccaggtat ccagtacgac cttgccaaag
     3661 tctttcaatc acaccacaat atgatggtgt ctcatgcacg cgcggtaaaa ttgtacaaag
     3721 agaaaggcta taaaggggaa attggtgttg ttcacgccct gccaactaaa tatcctctag
     3781 atcctgaaaa tccagcagat gttcgtgcag ctgagttgga agatatcatc cacaataaat
     3841 tcatcttaga cgcaacttat ctaggtcgct attcagctga aaccatggaa ggtgtcaacc
     3901 atatcttatc agtcaatggt ggtagcttgg atcttcgtga agaagatttt acagcattag
     3961 aagctgcaaa agacttgaat gatttcctag gaatcaacta ctatatgagt gactggatgg
     4021 aagcctttga tggagaaact gaaattatcc ataatggtaa aggtgaaaaa ggaagctcta
     4081 agtatcaaat caaaggtgtt ggtcgtcgtg tagctcctga ctatgtacca cgcacggatt
     4141 gggattggat tatctaccct caaggtttgt atgaccaaat catgcgtgtg aagaaagatt
     4201 atcctaacta caagaagatt tacatcactg aaaatggtct cggctataaa gatgagttcg
     4261 ttgataacac tgtttacgat gatggtcgta ttgattacgt gaaacaacac ttggagatct
     4321 tgtctgatgc gattgcagat ggagctaatg taaaaggtta cttcatttgg tcattaatgg
     4381 atgtcttctc atggtcaaac ggttatgaga aacgttatgg tctcttctac gtagattttg
     4441 aaactcaaga acgttatcct aagaaatcag ctcactggta caagaaagta gcggaaactc
     4501 agattataga ctagtagaat tagtcattag atatagaatt ttagtgagtc aaaaagatgt
     4561 tcaaagattt tatccaatct atttatgaaa aagtttatat tataaatttc gaaaaatgct
     4621 ctcaaatacc gtgtttgacg agtgaagaat tgaaaagtct tggaaaatgg tatgtctcga
     4681 ctggtaaaga atggatttgt cattcagatg atgagctgga agaatttaaa aatctatttt
     4741 taaattttat caatcctgaa ggatgggata ctatctcctt tgattcagat tttatgccgt
     4801 ttcaacaatc gtaaccaatt tctcaaaaaa gttaaatctt atatttagta ctctgtaaaa
     4861 ctcttatcta atcacgttgc ttatactcaa tgaaaatcaa agagcaactt taaactagga
     4921 agcgagtcgc agatttctca atgcatagct ttgaggaatt gggcaaaaag tctttgatat
     4981 agaaaaacgc atagtatcag gtgttgaaac acctgatact atgcgtttta ttgtgggaag
     5041 atttactttt tttcttctga aattgagttg ttacccaggc tctttcagtt tattaaggct
     5101 tgatgacttt aatgtgttta gatagcttaa aaaggattga atcacttagt ttagaatctg
     5161 aaacaatagt atcaagattt gatacattat aaaaagtata aaaatcaaac ttattgaact
     5221 tgctatgatc tgcgagtaaa tattttttat tagaattatt taaagcgatg cgttgagcct
     5281 ctccctcttc ctcgctaaaa gtagctagag ctccgttttg aataccatta cagctaacga
     5341 aagctttaga aaattggaga ttagagagat tttgtagggt caatgtacca acaaaagcac
     5401 ctgtaatatc gcgataattt ccacctatta aaatcaaatc tgttaatttt cgttcgctta
     5461 aaatcagaaa aacaggtaga ctgttggtta cgacgcggat attgtcaata ggcaactcac
     5521 gcgcaaaaaa ctctaatgtt gttcctggtc caatgaaaat agtttctctt tcttctacta
     5581 gactgcctgc aaaatgggct atttcttgtt tttctgccgt ttggagggct tgtttttcaa
     5641 tatttgatcg ctcattagtc aaaagggagt tggttcgaag tttttcagct ccaccatgca
     5701 cacgaatcag caaatcttta tcagctaatt cctgtaaata gcgccttgca gtcatatctg
     5761 aaacggctat ttcgtccata atctgtttaa ctgttatggt tcctttacta tttactatct
     5821 ctaaaatttt ggctaatttt tcttgtttga gcatattatc acctcgtttc ctactactat
     5881 cttaccataa acaaactcat cattcaaata caaaaacaac aaaatgaaac aaaaacaaaa
     5941 atatcgaagt ttgttttcaa aactttcgat atttttgttg ggttataact ttgatgtttc
     6001 tagtttactt tttgatgatt gagagtgatg gagaattagt ctaaaccgta gttatagtca
     6061 tcgtcttgca tggcttcaac ttcgccaaga aggtaaccat ttccgacttg agagaagaag
     6121 tcatggttgg aagttcctgt tgaaataccg ttcataacga ttgggttgac atcttcagct
     6181 gaatctggga aaagtggatc ttgtcccatg ttcatgagag ctttattggc attgtagcga
     6241 aggaaggttt taacctcttc agtccaacca acaccgtcat aaagactctc tgtgtagcct
     6301 tcttcatttt cataaagagt atagagtagg tcgtacatcc attctttgag tttttcttgc
     6361 tcttcttcag gcaattcatt gaaaccaagt tggaatttgt aaccaatgta ggttccgtga
     6421 acagactcgt cacgaataat caatttaatg atttctgcaa cgttggcaag tttgttgtta
     6481 ccgagatagt agaggggagt gaagaaacca gagtagaaga ggaaggtttc gaggaagacg
     6541 ctggcaactt tcttttcaag tgggctgccg tttaggtaga tttcgttgac aatctcagcc
     6601 ttcttttgta ggtaaggatt ggtattggtc cattcgaaaa tttcttcaat ctcagcctta
     6661 gtattcaagg tagaaaagat tgatgagtaa gatttagcgt ggacagattc cataaattgg
     6721 atgttattga aaacagcttc ctcatgtggt gtacggatgt ctgcgcgaag ggcttgaacc
     6781 ccagtttcag attgcatagt gtcaagaagg gttaaaccac caaaaacttt tccgaccaag
     6841 tctttctctt tgttagatag ctttctccag tcatccaagt cgtttgataa gggaatacgt
     6901 gtatcgagcc aaaattgctc cgtcagtttt tcccaagttg atttgtcgat gacatcttcg
     6961 atggcattcc agttaatggc tttgtagtaa gtttccattt aaaatctctt tctgtgttta
     7021 gtattgcgaa ctcacaatta tttctacttt accataattc tataggagta tcgcacaaaa
     7081 agtcggaagc ccgactttta aaatgttaca taaattatgt tatgacatag tagatttgat
     7141 tttatcagtg ctgcttaggg aaaaatagtg tttctatgct agaaactaaa tcacacagct
     7201 ttcacattgg ttggcgccga cttctccacc gtcatctgta aaggtacgga cgtagtagat
     7261 agacttgatt cccttgttaa aggcatagtt acgaaggatg gacaaatcac gtgtcgtttg
     7321 tttattttcc ctcttccatt cgtaaaggcc ttttggaatg tcactacgca tgaagagggt
     7381 gagtgaaagt ccttgatcca cgtgttcagt cgcagcagcg taaacatcga tgactttacg
     7441 catatccata tcgtaggcag aagtgtagta aggaatggtt tctgtagaca agccagcagc
     7501 agggtagtag attttaccaa ttttcttctc ttggcgttct tcgatacgtt gcgtaatcgg
     7561 gtggatagaa gcagaaacgt cgttgatata gctgatagaa ccatttggcg ctacagcaag
     7621 gcgattttgg tggtaaagac catcttcttg aaccttgtcg cgaagttcag cccaatcagc
     7681 aacaccaggg ataaagacat ttttgaagag ttctttaaca cggtctgatg ttggaacaaa
     7741 ttcaccagtt acatacttgt caaagtaact tccgttagca tagtctgatt tttcaaagtt
     7801 gtggaaggta ataccacgtt cacgcgcaat attgtttgac tctaccaagg tccagtagtt
     7861 cataagcata aagtagatgc ttgtaaattc aacagactca ggtgaaccat attcaatgag
     7921 ttgttgggca aggtagctgt gcagtcccat ggcaccgaga ccaaaggtgt gggcttggct
     7981 atttccatgg tcaatcgttg gtacagctac gatatgtgaa ctatctgtaa cgaaagtaag
     8041 ggcacgaacc atagcacgga tagaacgacc aaaatcaggt gaagtcatca tgttaaccac
     8101 gttggttgaa cccaggttac atgaaacatc tgttcccatt tgaaggaatt cttgagcatc
     8161 gttgatcaag cttggttctt gaacttgaag aatctcagaa cacaagttac tcatgataat
     8221 ctttccatca acaggatttg cacggttagc cgtatcgatg ttgactacat aaggatagcc
     8281 agactcttgt tgcaatttag agatttcagt ttccaaatcc cgcgccttga tttttgtctt
     8341 gcgaatattt ggatttgcga ccaattcatc gtatttttca gtaatgtcga tgtaattgaa
     8401 tggcacaccg tattcttttt ctacagagta agggctgaag aggtacattt cttcattttt
     8461 acgagccaat tcgtagaatt tatcaggtac tacaacacca agtgatagag tcttgacacg
     8521 tactttttca tcagcgtttt ctttcttagt tgaaaggaaa gcgatgatat ctgggtgaaa
     8581 gacgttgagg tagacaacac cggcaccttg acgttgcccc aattggttgg agtaagagaa
     8641 gctgtcttca aaaagcttca taacaggaac gacacctgaa gcagctcctt catagccttt
     8701 gataggtgca ccagcttcac gaaggttgct gagggtaatt cccacaccac caccaatacg
     8761 tgaaagttga agagctgagt tgatagaacg tccgatagag ttcatatcat ccgtcacttg
     8821 gattaggaaa caagatacca actccccacg gcgagcacgt ccagcattca agaaggaagg
     8881 agtagcaggt tggtagcgtt ggtggatgat ttcattggca atatcgattg caacagcttc
     8941 attcccatca gcgaaataaa gggcgttgaa gaagacacgg tcttccatat tttcaagata
     9001 gtattcaccg tcattagtct ttaaggcata ttgattgtaa aatttataag ctgccatgaa
     9061 tgacttgaat tggaagtttt ggtctttgat aaattgagcc aattcttcca agaactctgg
     9121 acggtatttc ttgataaagg ctgtttcgat gtagttgtgt tcaatgaggt aattgatttt
     9181 gtctttgatt gaatcaaaaa ccatagtgtt tggaactaca ttttctttaa agaaagcatc
     9241 caaggcttcc ttgtctttat gaagcatgat ttgtccatta acaggacggt taatttcgtt
     9301 attaagacgg aagtaagtca cgtcttcaag atgttttaat cccataaaat ttcccttatc
     9361 taattacaaa agaaaggctt ctaagttagc cctaaaagca gttttttctg gatgatgtac
     9421 taagattatg ctaattgctt cagttttcct ggttggaaac ctgaaaagac ttcagttggt
     9481 gtttggataa caggagctgc gctaaaaccg agctctttaa cttgatcgac gtactcaggt
     9541 tgctcatcaa gattgatttc acgataagag acattattac tgtccaagaa acgcttggtc
     9601 attttacatt ggacacaatt gtttttagaa taaacggtta ccattgtgta actcctcttc
     9661 aaaatttaat actatcttag tatatcagaa aataaaattt tgtcaatgat ttgaactaaa
     9721 tatagtggtg ttcttttgtt gtttttatat ataaacacaa tatatagtgt ttgtgttgtg
     9781 aaatagcaat gattatccta taaattgttt ttgaagaaac tatatcctgt gttttgttat
     9841 ctaggataga agattttcag caagttatct gaaaggaaat tgaaggaaaa tccagaaaat
     9901 gcttgaaaaa aatcctagaa gatggtataa tactaaattg taagggttat cacatataac
     9961 tcaaaaaaag aaagaacaaa aggagagtca aactatggct tctaaagatt tccacgtagt
    10021 ggcagaaaca ggtattcacg cacgtccagc aacattgttg gtacaaactg ctagcaaatt
    10081 tgcttcagat atcactcttg agtacaaagg taaatcagtt aaccttaaat caattatggg
    10141 tgttatgagt cttggtgttg gccaaggtgc tgacgtaact atctcagctg aaggtgcaga
    10201 tgcagatgac gctatcgctg caatctcaga aacaatggaa aaagaaggat tggcataagg
    10261 gaaatgacag aaatgcttaa aggaatcgca gcatctgacg gtgttgcagt tgcaaaagca
    10321 tatctactcg ttcagccgga tttgtcattt gagactatta cagtcgaaga tacaaacgca
    10381 gaagaagctc gccttgatgc cgctctacag gcatcacaag acgagctttc tgttattcgc
    10441 gagaaagcag taggtacgct cggtgaagaa gcagctcaag tttttgatgc tcacttaatg
    10501 gttcttgctg acccagaaat gatcagccaa atcaaggaaa ctatccgtgc gaagaaagtg
    10561 aatgcagaag caggtctgaa agaagttaca gatatgttta tcactatctt tgaaggcatg
    10621 gaagacaacc catacatgca agaacgcgca gcggatatcc gcgacgtgac aaaacgtgta
    10681 ttggcaaacc ttcttggtaa aaaattgcca aacccagctt ctatcaatga agaagtgatt
    10741 gtgattgcgc atgacttgac tccttcagat acagctcaat tggacaaaaa ctttgtaaaa
    10801 gcttttgtaa ccaacattgg tggacgtaca agccactcag ctatcatggc acgtacactt
    10861 gaaattgctg ctgtattagg tacaaacaac atcactgaaa tcgttaaaga cggtgacatc
    10921 cttgctgtta acgggatcac tggagaagtg attatcaacc caacagatga acaagcggca
    10981 gaatttaaag cagctggtga agcctatgcg aaacaaaaag ctgaatgggc acttttgaaa
    11041 gatgctcaaa cagtgactgc tgacggtaaa cacttcgagt tggctgccaa tattggtact
    11101 ccaaaagacg ttgaaggtgt taacaacaac ggtgcagaag ctgttggact ttaccgtaca
    11161 gagttcttgt acatggattc tcaagacttc ccaactgaag atgagcagta tgaagcatac
    11221 aaggctgttc ttgaaggaat gaacggtaaa cctgttgtcg ttcgtacaat ggatatcggt
    11281 ggagataagg aacttcctta cttcgatatg cctcacgaaa tgaacccatt ccttggattc
    11341 cgtgctcttc gtatctctat ctctgagact ggagatgcta tgttccgcac acaaatccgt
    11401 gctcttcttc gtgcgtctgt tcacggtcaa ttgcgtatca tgttcccaat ggttgcgctc
    11461 ttgaaagaat tccgtgcagc gaaagcagtc tttgatgaag aaaaagcaaa ccttcttgct
    11521 gaaggtgttg cagttgcgga taacatccaa gttggtatca tgatcgagat tcctgcagca
    11581 gctatgcttg cagaccaatt tgctaaagaa gttgacttct tctcaattgg tacaaacgac
    11641 ttgatccaat atacaatggc agcagaccgt atgaacgaac aagtttcata cctttaccaa
    11701 ccatacaacc catcaatcct acgcttgatt aacaatgtga tcaaagcagc tcacgctgaa
    11761 ggtaaatggg ctggtatgtg tggtgagatg gctggtgacc aacaagctgt tccacttctt
    11821 gtcggaatgg gcttggatga gttctctatg tcagcaacat ctgtacttcg tacacgcagc
    11881 ttgatgaaga aactcgacac agctaagatg gaagagtacg caaaccgtgc ccttacagaa
    11941 tgctcaacaa tggaagaagt tcttgaactt caaaaagaat acgttaattt tgattaatcg
    12001 aaaaatccct gcaactcagt tacagggatt tttttgatat tttaaaaaga attttcaaga
    12061 aaatctttct tatagaaagt ccaaccttga aaaagtagtg gtcagaacaa aaaatactta
    12121 aatggttcat aaaattcttg acaagttgga gatttaggag taaactatta accagttaag
    12181 taatagagag gagtttctgc aatttagaaa tgaattgcaa ctagaaatat caaatagaaa
    12241 gagagtttcg atgaaaatta ataagaaata ccttgttggt tctgcggcag ctttgatttt
    12301 aagtgtttgt tcttacgagt tgggactgta tcaagctaga acggttaagg aaaataatcg
    12361 tgtttcctat atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga
    12421 ggttagcaag cgtgaaggaa tcaatgctga gcaaatcgtc atcaagataa cagaccaagg
    12481 ctatgtgact tcacatggcg accactatca ttattacaat gggaaggttc cttatgacgc
    12541 tatcatcagt gaagaattgc tgatgaagga tccaaactac cagctaaaag acgaggatat
    12601 tatcagtgaa atcaagggtg gttatgttat caaggtagat ggaaaatact atgtttacct
    12661 taaggatgct gcccacgcgg ataatgtccg tacaaaagaa gaaatcaatc ggcaaaaaca
    12721 agaacatagt cagcatcgtg aaggagggac ttcagcaaac gatggtgcgg tagcctttgc
    12781 acgttcacag ggacgctaca ccacagatga tgggtatatc ttcaatgcat ctgatatcat
    12841 tgaggacacg ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa
    12901 gaatgagtta tcagctagcg agttggctgc tgcagaagcc ttcctatctg gtcgggaaaa
    12961 tctgtcaaat ttaagaacct atcgccgaca aaatagcgat aacactccaa gaacaaactg
    13021 ggtaccttct gtaagcaatc caggaactac aaatactaac acaagcaaca acagcaacac
    13081 taacagtcaa gcaagtcaaa gtaatgacat tgatagtctc ttgaaacagc tctacaaact
    13141 gcctttgagt caacgccatg tagaatctga tggccttatt ttcgacccag cgcaaatcac
    13201 aagtcgaacc gccagaggtg tagctgtccc tcatggtaac cattaccact ttatccctta
    13261 tgaacaaatg tctgaattgg aagaacgaat tgctcgtatt attccccttc gttatcgttc
    13321 aaaccattgg gtaccagatt caagaccaga agaaccaagt ccacaacctg caccaaatcc
    13381 tcaaccagct ccaagcaatc caattgatga gaaattggtc aaagaagctg ttcgaaaagt
    13441 aggcgatggt tatgtctttg aggagaatgg agtttctcgt tatatcccag ccaaggatct
    13501 ttcagcagaa acagcagcag gcattgatag caaactggcc aagcaggaaa gtttatctca
    13561 taagctagga gctaagaaaa ctgacctccc atctagtgat cgagaatttt acaataaggc
    13621 ttatgactta ctagcaagaa ttcaccaaga tttacttgat aataaaggtc gacaagttga
    13681 ttttgaggct ttggataacc tgttggaacg actcaaggat gtcccaagtg ataaagtcaa
    13741 gttagtggat gatattcttg ccttcttagc tccgattcgt catccagaac gtttaggaaa
    13801 accaaat
//
LOCUS       DAVIME010000056        13654 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVIME010000056 DAVIME010000000
VERSION     DAVIME010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13654
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.056"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(98..2356)
                     /locus_tag="VV588_001837"
     CDS             complement(98..2356)
                     /locus_tag="VV588_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU7084127.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VV588_001838"
     CDS             complement(2585..2815)
                     /locus_tag="VV588_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU7084128.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VV588_001839"
     CDS             3005..3688
                     /locus_tag="VV588_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU7084129.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VV588_001840"
     CDS             3688..4422
                     /locus_tag="VV588_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU7084130.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VV588_001841"
     CDS             4576..5433
                     /locus_tag="VV588_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU7084131.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAMDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VV588_001842"
     CDS             5575..6447
                     /locus_tag="VV588_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU7084132.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VV588_001843"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VV588_001843"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU7084133.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VV588_001844"
     CDS             7426..8637
                     /locus_tag="VV588_001844"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU7084134.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VV588_001845"
     CDS             8639..9181
                     /locus_tag="VV588_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU7084135.1"
                     /translation="MTRYSLLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VV588_001846"
     CDS             9197..10006
                     /locus_tag="VV588_001846"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU7084136.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGGFKGLLKAILAEL"
     gene            10482..10877
                     /locus_tag="VV588_001847"
     CDS             10482..10877
                     /locus_tag="VV588_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU7084137.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10887..11462
                     /locus_tag="VV588_001848"
     CDS             10887..11462
                     /locus_tag="VV588_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU7084138.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11534..11998
                     /locus_tag="VV588_001849"
     CDS             11534..11998
                     /locus_tag="VV588_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU7084139.1"
                     /translation="MELEGYNALSLAEVEVFRFIATNAETATQVSKPVQPISQTPVKD
                     KTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGCNQTAGFVLNLPIKENM
                     RNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTLNSKVSDDDVL"
     gene            12656..13366
                     /gene="deoD"
                     /locus_tag="VV588_001850"
     CDS             12656..13366
                     /gene="deoD"
                     /locus_tag="VV588_001850"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU7084140.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13389..>13654)
                     /locus_tag="VV588_001851"
     CDS             complement(13389..>13654)
                     /locus_tag="VV588_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU7084141.1"
                     /translation="DLPTTNIIEPFKRYLKYRGKVRESMAADCPERFDWEFIRWILWD
                     GRSKTQKENYQKLCQEYSHKVTILRNQRELDQFLDKKRKSYNS"
BASE COUNT         4024 a         2512 c         3084 g         4034 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttatca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggggcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcactaat tctgctagtt taaagatttt taaataaatt ggataaaaga
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc aacaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa caggtctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc catggatcca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtcatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa tcgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttattgta taataaaagt gagaggaaaa aaggatgaaa
     5581 gtgattaatc aaaccttatt agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagttg tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagag
     6421 agggtaagta aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagattt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat tctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggagctt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gcctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcttac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggccggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtggtttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggaggctacc
    10741 tagctcagat tgcagcggtt gaagattacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttgggatg
    10861 ctaagaatgg tttctgagat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aataatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctacctcaat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa caggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa acttccaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aatatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaac
    11521 gcgctatgtt cggattgagc tagaaggcta taatgccctc agtcttgcag aagttgaagt
    11581 tttccgcttt atagctacga atgctgaaac ggcgacacaa gtttctaagc cagttcaacc
    11641 aatcagtcag actcctgtga aagataaaac attgacaatt caacacagtg gagcttacat
    11701 tgcccgctac tccataactt gggaagaagt tccagtagat aaagatggaa accaagttgt
    11761 tcgtagtcat tcttgggaag gaaacggttg caaccagact gcaggttttg tcctcaacct
    11821 cccaatcaaa gaaaatatga gaaatctgcg agttaagatt gagaaaaaga cgggcctact
    11881 atggaataga tggcaaacaa tctatgaaaa cagaccaatt ttagctcaac cccaccgtaa
    11941 aattacccat tggggtacga cattgaattc caaggtgagt gacgatgatg tcttgtaatc
    12001 tgatggtaca atgacagtta gtttgtctag tttataagaa agtactacct gagcttgaat
    12061 agaactcagg tagctctctg tgaaagaaca aaattaatac tcaatgaaaa tcaaagagca
    12121 aactaggaaa ctagccgcag gttgctcaaa gcactgcttt gaggttgtag ataagactga
    12181 cgaagtcagt cacatatata atccaaggcg acgttgacgt ggtttgaaga gattttcgaa
    12241 gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa cacgagtaga aaacttttct
    12301 aaaaacaaaa acgaaaggat gggtaaactg tattcgctga actgaatacg ggcgactctc
    12361 ctctaaatca aaattaagaa agaaaggaat tgaccccacc ctaaaagcag tgggaaaaag
    12421 atagttggtc tagcgagcat cgctcactgc gcccaactcc tattttccct tcgctttttg
    12481 acgggtttgg tatctttctc aatataaaat ataaaataaa gaaaggtaga gcgtgtgttt
    12541 tgatttgaac acgagcggaa aactcggaaa atagataatc tgactgaaaa atcaggattt
    12601 ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc tttgtatcat aaattatgtc
    12661 tatccatatt gctgctcagc agggtgaaat tgctgataaa attcttcttc ctggggatcc
    12721 tcttcgtgct aagtttattg cggagaattt ccttggtgat gctgtttgtt ttaacgaagt
    12781 gcgtaacatg tttggttaca ctggtactta caagggtcac cgtgtatctg tcatgggaac
    12841 tgggatggga atgccatcta tttcgattta tgcgcgtgag ttaatcgtag actacggtgt
    12901 gaagaaattg attcgtgtgg gaactgcagg ttctttgaat gaagaggttc atgttcgtga
    12961 attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc gttcgtaatg actggccaca
    13021 gtacgatttt ccacaaattg ctagctttga tttgcttgat aaagcctacc atatcgccaa
    13081 agaacttggt atgactactc acgttgggaa cgttttgtca tctgatgtct tttactcaaa
    13141 ttactttgaa aagaatatcg agcttggtaa atggggagtc aaggctgtgg aaatggaagc
    13201 agcagctctt tactatcttg ctgcccaata ccatgttgat gcgctagcta tcatgaccat
    13261 ctctgatagc ttggtcaatc cagacgaaga cacaactgca gaagaacgtc aaaatacctt
    13321 cactgatatg atgaaggttg gtttggaaac cttgattgca gaataattat agccaaaaag
    13381 gaagcccttt atgaattgta ggacttcctt ttcttatcca gaaattgatc tagctctctc
    13441 tgatttcgaa gaatagtgac tttatgtgaa tattcttggc aaagtttttg gtaattttct
    13501 ttttgagttt tgctacgtcc atcccaaaga atccatctga taaactccca gtcaaagcgt
    13561 tcagggcaat ctgccgccat actttctctg acttttccac ggtatttaag ataacgctta
    13621 aagggctcta taatatttgt agtgggtaaa tcca
//
LOCUS       DAVIME010000057        13133 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVIME010000057 DAVIME010000000
VERSION     DAVIME010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.057"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            192..752
                     /locus_tag="VV588_001852"
     CDS             192..752
                     /locus_tag="VV588_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU7084142.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            753..2138
                     /locus_tag="VV588_001853"
     CDS             753..2138
                     /locus_tag="VV588_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084143.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            2140..2790
                     /locus_tag="VV588_001854"
     CDS             2140..2790
                     /locus_tag="VV588_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU7084144.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFLPSIALNLLVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            2801..3559
                     /gene="tenA"
                     /locus_tag="VV588_001855"
     CDS             2801..3559
                     /gene="tenA"
                     /locus_tag="VV588_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU7084145.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEEWKHEKAPTTSSQINHFIYDDCP"
     gene            3498..4022
                     /gene="thiW"
                     /locus_tag="VV588_001856"
     CDS             3498..4022
                     /gene="thiW"
                     /locus_tag="VV588_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU7084146.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            4022..4825
                     /locus_tag="VV588_001857"
     CDS             4022..4825
                     /locus_tag="VV588_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU7084147.1"
                     /translation="MQEFTNPFPIGSSSLIHCITNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            4818..5450
                     /locus_tag="VV588_001858"
     CDS             4818..5450
                     /locus_tag="VV588_001858"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU7084148.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKIETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(5659..6450)
                     /gene="thiD"
                     /locus_tag="VV588_001859"
     CDS             complement(5659..6450)
                     /gene="thiD"
                     /locus_tag="VV588_001859"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU7084149.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(6534..6632)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6816..7211
                     /locus_tag="VV588_001860"
     CDS             6816..7211
                     /locus_tag="VV588_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU7084150.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVDKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            7222..7593
                     /locus_tag="VV588_001861"
     CDS             7222..7593
                     /locus_tag="VV588_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU7084151.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKRSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            7603..9846
                     /locus_tag="VV588_001862"
     CDS             7603..9846
                     /locus_tag="VV588_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU7084152.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKEIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNILGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            10053..11828
                     /gene="spxB"
                     /locus_tag="VV588_001863"
     CDS             10053..11828
                     /gene="spxB"
                     /locus_tag="VV588_001863"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU7084153.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNVEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            11939..12286
                     /locus_tag="VV588_001864"
     CDS             11939..12286
                     /locus_tag="VV588_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU7084154.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(12403..13133)
                     /locus_tag="VV588_001865"
                     /pseudo
     CDS             complement(12403..13133)
                     /locus_tag="VV588_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         3747 a         2535 c         2895 g         3956 t
ORIGIN      
        1 tcttttacga aactggatga agatgatata gtagattgaa ataagatgcg aacaaatcaa
       61 ttagaaaatt caaattaatt tctagaaata ttttagcatt cttgtgtact gttctaaatt
      121 cagtctgcta tacaaagtat ttaggtcggt cttcttgagt gccccacttt tctttaaaaa
      181 aaggagtttt tatgttgaaa aaatggcagt taaaagatgt tatcttgctt gctttcttgt
      241 ctatcttttt tggtggggtt ttcgttggtt caggatatgt gtataatatt ctcagtctac
      301 tcttaacacc tcttggtttg caggcctttg ccaatgaaat cctcttcggt ctctggtgta
      361 tggctgcgcc cattgctgcc atctttgttc caagagtcgg aagtgcaacg attggagaag
      421 tgctagctgc gcttgctgaa gtcctttatg gtagccaatt tggtctagga gctcttttgt
      481 ctggcttggt tcaaggtttg ggaagtgaat ttggttttat cgtaactaag aatcgctatg
      541 aaagttggct ctctctaact gctaatagta ttgggattac gcttgttagc tttgtctatg
      601 aatacattaa gttaggttac tacgcctttt cccttccgtt tgtcctttcc ttacttgtgg
      661 tacgttttat ttctgtttat ttcttctgta ccatcttggt tcgtgccatt gtcaaactct
      721 atcatcagtt tgcaactgga ggaaaagcat agatgggtct ggaactacga gcgattcagt
      781 ccccaatctt ctctgagccg tttgatttta cttttcatgc gcaagccttt accttgttag
      841 ttgggagcag tggttcagga aaatccagcc tttttcaagt cattgcccaa gtcagttctc
      901 ttccctatag tggtcaagtc ctgatagatg ggagcgaggt cagtcagctt tctatcatcg
      961 cacgtgtcca gaaggttggc attctcttgc aaaatcccaa tcatcaattt accatggaga
     1021 acttgtttga ggagttgatt ttcaccttgg agaatatcgg ctatcacctt caggaaattg
     1081 attctaaaat agcagaggtt gtccagcaat gtcgttgcga ggcaatctta caccgtccca
     1141 ttcatcacct atcaggtggg gaaaagcaaa aagcagcgct ggctgtcctc tttgccatga
     1201 atcctagggt ctatctcttg gatgagccct tcgcttccat tgaccgcaag agtagaatcg
     1261 agatattgga gattctaaaa gagttggctc ttgatgggaa gacagtcatt ttgtgcgacc
     1321 atgatttatc tgactataaa gcctatatcg accatatggt tgagctaaga gacggaaaac
     1381 taagggaagt gtttcaaatc ccttcctatg agatgacaca ggttgcttca aaggaagttg
     1441 ctgctagccc ggaattattc catatgaacc gtgtgactgg tgagcttgga aatcgctccc
     1501 tcttttcgat tgctgatttc acattctatc aagggatttc ctgtatcctg ggtgacaatg
     1561 gtgtcgggaa atcaaccctc tttcgctcta ttcttcaatt tcaaaagtat aaggggcgca
     1621 ttacttggaa gggttcggtc ctgaaaaaga aaaagagttt gtatcgtgat ctgactggtg
     1681 ttgttcagga agctgagaag cagtttatcc gagtcagtct gcgagaggag cttcaattag
     1741 atggacctga ttctgaaaga aatcagcgga tttttcaagc tttacgatat tttgatttgg
     1801 agcaggcagt cgataagagt ccctatcaat taagtggtgg tcagcaaaaa attcttcagc
     1861 tcttgaccat cttgaccagt aaggcttccg tgatcttgct agatgaacct tttgcaggtt
     1921 tggatgatag agcctgccat tatttttgca agtggattgt ggaggagagg aatcaaggaa
     1981 gaagttttct gctcattagt catcgtttag accctttgat ttctgtggtt gattattgga
     2041 ttgagatgac tagtcagggt cttcggcatg tgaaagaagt gaccattacc aaaccactta
     2101 catctcagag tagcaatacc caaggggagg tgagatagta tggtcaaagt agcaacccag
     2161 acaccgatta tcagtctctt cttgctgatt ttatccttgg aaacatcttt ccttccttcg
     2221 attgctctga atcttttggt agtcgcattt tgtattctct ttatgctcta ttaccgtcga
     2281 tttaaaatgt tagcttggat gatcatactt gccattttac catcttttgc caactactgg
     2341 gcagttcagt tacacggaga tgcttcacag gcagtcatgc ttggaacgag ggcctttgtg
     2401 acagtttgta tcggccttgt ctttgtttcc tctatttcac taaaagagct tctcttgtac
     2461 ttggctcaaa aggggctatc acgctcttgg tcctatgcct tgattgtggt attcaattct
     2521 tttcctctca ttcagcaaga aatcaagtcc ctcaaagaag cttgcctatt acgtggtcaa
     2581 gaactacatt tttggtcgcc cttgatttac agtaaggttc tgatgacagt ctttaggtgg
     2641 cgccatcttt acctgagagc tctatctgct cacggatatg acgaacatgc acagttgaag
     2701 aatagctatc ggacttttta tattcctaaa aaaacaaaat taatctacct gcttttcttt
     2761 ttattgcttc aaaccagtct atttttataa aggagttatt atggaattta cagatattgc
     2821 gatggaatta tccaagaaag cttggcaggc ttcctttcat catcccttta ttttacaatt
     2881 acaagagggg aatttagaac ctgccatttt ccgctattac ctgattcagg atgcctacta
     2941 tctgaaggcc ttctcagaaa tctatcatct tttggctgat aagacttcaa accaagagat
     3001 gaaaagactc ttgaaacaaa atgctcaggg tttagtggag ggtgagttat ttattcgcca
     3061 acaatttttc aaggaaatgg aaatcagcga ccaggaaatg gagcaacatc caatcgctcc
     3121 aacctgttat cattacattt ctcatattta taggcaattt gcagaaccga acttagccat
     3181 cgcttttgca agcttgcttc cttgtccttg gttataccat gatataggca aatcacttaa
     3241 tcttaaacca tcaccaaatc ctctctatca acaatggatt gaaacttata ttacggatga
     3301 gttagagcaa cagatcagag aggagggagc actggtcaat cagctctatc gagaaagtga
     3361 cgagacagac aagcaaaaaa tgctagatgc cttccacatc agtgttcata tggaagccaa
     3421 gttttgggaa atggcctacc aacaccagac atggaagagc gatttacagt ctttagaaaa
     3481 aggagaagaa tggaagcatg agaaagcacc aactacaagt tcacaaatta accattttat
     3541 ctatgatgat tgcccttgat gtagtcctta cacctatctt tcggattgag ggaatggcac
     3601 cgatgtccag tgtagtcaat attctagcgg gaatcatgat gggacctgtt tatgccttgg
     3661 ctatggctac agtgacagcc tttatccgta tgacgactca agggattccg cctttagctc
     3721 tcacaggagc gacttttgga gcccttctag caggtctctt ttataagtac ggtcgaaaat
     3781 tttacttttc tgccttggga gaaattgtgg gaacaggtat tattggttct attgtttcct
     3841 atcctgttat ggtactcttt acaggatcag ctgctaagct tagctggttt atctacacgc
     3901 ctcgattttt cggagcaacc ttgattggta cagcgatttc ctttattgcc tttcgatttt
     3961 taatcaagca ggaattcttt aaaaaagtgc agggatattt ctttagtgaa aggatagact
     4021 gatgcaggaa tttacaaatc cctttcctat aggctctagt tccctcattc actgcattac
     4081 caatgagatt tcttgtgaga tgctggcaaa tgggattttg gctctgggat gcaaacctgt
     4141 catggcagat gatccccgtg aggttcttga ttttactaag caaagtcagg ctctcttcat
     4201 caatttgggg catttgtcag ctgagaagga gaaagcaatc cgtatagcag cttcttatgc
     4261 agctcaagtt tgtctcccaa tggtagtaga tgcggttggc gtaacgactt catccattcg
     4321 taagagctta gttaaagacc ttttagacta tagacctacg gtccttaaag gaaacatgtc
     4381 agaaattcga agtcttgttg gattaaagca ccacggcgtt ggggtcgatg cgagtgctaa
     4441 agatcaagaa acggaggatt tgcttcaagt cttgaaagac tggtgtcaga cctatcctgg
     4501 tatgtcattc ttagttactg gccccaagga cctcatcgtt tcggagaatc aagttgctgt
     4561 actgggaaat ggctgtgcag aattagactg gataacaggg acaggagatt tggttggagc
     4621 cttaacagcc gtttttctca gccaaggaaa gactggtttt gaagcttctt gcttagcagt
     4681 ctcttatctt aatatcgctg ctgagaaaat agttgttcaa ggaatgggat tggaagaatt
     4741 tcgttaccaa gtactcaatc agctttcgct cctaagaaga gatgaaaatt ggctagatac
     4801 catcaaagga gaggtttatg aatagagaag cacttagact atatctggta accaatcgct
     4861 atcaagattc cgtggaaagc tttcttgcaa aaattgagac ggcctgccgt tcaggggtta
     4921 ccatagtcca attgcgagaa aaaaatctca caaccaatca atattatcaa ctggcaaaac
     4981 aagtcaagga aataacagat gcttatcagg tacccttgat aatcgatgat cggttggatg
     5041 tttgtcttgc ggttgatgct gctggtctgc atattggaga tgacgaactc ccagtttcgg
     5101 ttgcccgaca agtcttgggt cctgaaaaaa tcctcggtgt caccgctaaa acggttaaaa
     5161 gagctctgga agcggagaaa tcaggtgcag attacttggg gacaggagcc atttttccga
     5221 caaccaccaa ggaaaatgca cccatcaccc tgatttcaac cttgaaaaca atttgccaaa
     5281 cggttgccat tccaatagtt gctattggcg gcttgacttc ggagaatatt gatcagctta
     5341 tgggcactgg catagctggt gtagctgttg tacgtgattt gatgcaagca gaagatattg
     5401 aggcaaaaac gcaagccttt ttaacaaagt tgcatgacat tctttcctaa ttaatactca
     5461 atgaaaatca aagagtaaac tagaaagcta gtcgcaggtt gctcaaagta ctgccttgag
     5521 gttttagata agactgacga agtcagctca aaacagtgtt ttgaagttgc agatggaagc
     5581 tgacgtagtt tgaagagatt ttcgaagagt ataaaaactc tctaattccc ttaaagtggg
     5641 aactagagag tttttttctt aatctttaaa agttgtatgg ttgactggac cagaaccatg
     5701 accgagttga ggggcatctt gaatagcttt tgtgataaag gccttggcct tatcaactgc
     5761 ctggtaaaga ctcttgccct tggctagttc agcagtaatc actgcagcaa aggtacatcc
     5821 agtaccatgg gtgtgacagg tttgaattcg tgggctttcc cagacaaatt gttcattctt
     5881 ggtaaagagg aaatctttag caccaccttt gagatgtccg cctttgataa ccacagactg
     5941 aggaccaaat tcttttaaaa tcaggcgacc agcacgctgc atgtcttcgg ggtcatggat
     6001 tgaaaaacca acaatctctt ctgcttcagg aagatttggc gtaataatag ttgctagagg
     6061 tagtaagttt gttttgagat agtctctagc atttgagtca atcaaggcat ctccacttgt
     6121 agcaaccata acaggatcaa ggacataggg acaatccagt tttttaagat agggttggat
     6181 gatttccatg atttcagtag tagccaacat tccagttttt acagcctgag gtggaatatc
     6241 agaaaagaca ctctccaatt gggctttcaa catttgagga gaaacgtgct cgattagctg
     6301 aacacctctg gtattttgag cgacaagact ggttacaaca gccattccat agacatctct
     6361 cgcttggaat gactttaaat ctgccataat gccagcacca ccactagggt cagtccctgc
     6421 aatggtcaaa gcaacgggta aataagtcat ctaaaacctc ccaaccaact gaagtttgta
     6481 ttcttaagaa caagctagtc tgttttagaa aggcaataga agactgctag tccccattat
     6541 catttccact tccatcagct agcattacct agattgagtc agagggatct agcagtcgtt
     6601 aatctcagct ttacgcaccc ctagtggttg ttttcttttt tctttagtat agcatatttt
     6661 tattgtttat atagtaatat ttgactgcaa atcgtttttc aaatgattaa aattctattt
     6721 ttcgaagaaa atattatttc tataattgac aaatgtagat tttaagagta tactgataag
     6781 tgtaattgac aaatgtagat tttggaggta tggtaatgca gatttcagat gcagaatggc
     6841 aggtcatgaa gattatttgg atgcaggggg agcagaccag tacagatttg attagggttt
     6901 tggcagagcg gtttgactgg tccaagtcca cggttcagac acttttggct cgtctggttg
     6961 ataaagagtg tttgactcgg aaaaaagaag gcaagtcctt tgtttattca gcccttttaa
     7021 ctctagacca aagtcgggat ttacttgtcc aagatatcaa agacaaggtt tgttcccgta
     7081 ggattaggaa tttgttggct gacttgattg tagaatgtga atttactcag actgacttgg
     7141 aagacttgga agctgtgatt tcagagaaga aatcaagtgc tgtaacagaa gtaagatgta
     7201 attgtatgta aaggagacgt catgttaaat agtattgtaa ccattatttg tattgctctt
     7261 atcgcgttta tcttgttttg gtttttcaaa aagcctgaaa aatctggaca aaaagcccag
     7321 caaaaaaacg gataccaaga gattcgagtg gaagtcatgg gaggctatac tcctgagttg
     7381 attgtcctca agagatcagt gccagcccgc attgtctttg accgcaagga tccttcacca
     7441 tgtctggatc aaattgtttt tccagatttt ggtgtacatg cgaacctgcc aatgggggaa
     7501 gagtatgtag tggaaatcac gcctgagcag gctggagagt ttggctttgc ttgtggtatg
     7561 aacatgatgc acggcaagat gattgtagag taggtggaga ctatgacaga aattgtgaaa
     7621 gcaagcttag aaaatggcat tcaaaaaatc cgtatccgag ctgaaaaagg ctatcatcca
     7681 gcccatatcc agcttcaaaa ggaaattcca gctgagatta cctttcatcg tgctactcct
     7741 tcaaactgtt ataaggaaat tctgtttgaa gaagaaggta tcttggaacc aatcggcgta
     7801 gatgaggaga aagtcattcg ttttacacct caagaattag ggcgacatga attttcttgt
     7861 ggcatgaaga tgcaaaaggg aagctatata gtcgttgaga agactcgaaa atctctatct
     7921 ctcctgcaac gtttttggat tactagtatc tttactgtgc ctcttgtgat tctcatgatt
     7981 gggatgttga caggtagcat tagtcatcaa gtcatgcatt ggggaacctt tctagcaaca
     8041 acgcctatta tgttagttgc aggtaagcca tatatccaga gtgcttgggc cagttttaaa
     8101 aagcacaatg ccaacatgga taccttggtt gcgctgggaa ctctagtggc ttatttctat
     8161 agcctagttg ctctctttgc tggtctccct gtttacttcg aaagtgctgg atttatcctc
     8221 tttttcgttc ttttgggagc agtttttgag gaaaaaatga gaaaaaatac gtcccaagct
     8281 gtggagaaat tactggactt gcaagctaaa accgcagaag tcttgagtga tgatagttat
     8341 gtccaagttc ctttggaaca agtcaaggta ggcgacctga ttcgagtgcg tcccggtgaa
     8401 aagattgctg ttgatggtgt cgtagtagaa ggtgtctcta gtattgacga atccatggtg
     8461 acaggtgaga gtctgcctgt ggacaagaca gttggagata ctgtcattgg ctcaaccatc
     8521 aatcatagtg gaacgcttgt ctttagagca gaaaaagttg gctcagagac tgttttggct
     8581 cagattgtgg attttgtgaa gaaagctcag acaagtcgtg cgccgattca ggacttgacg
     8641 gataagattt cagggatttt tgtcccagta gttgtcattt taggaatcat gaccttttgg
     8701 gtttggttcg tcttgctcag ggatagtgtg gttgtgcttg gagctagctt tgtgtcctct
     8761 cttctctacg gagtggcggt tttgattatc gcctgtcctt gtgccttggg acttgcaaca
     8821 ccgacagccc ttatggtggg gacaggacgt agtgccaaga tgggggttct cctcaaaaat
     8881 ggaactgtct tacaggaaat ccagaaagtt caaacccttg tctttgataa gaccgggact
     8941 ttgacggaag ggaaacctgt ggtaacagat gtcatcggcg acgaagtaga agtgtttggg
     9001 ttggcagcct ccttggaaga tgcttctcaa cacccactgg ctgaggctat cgttaagcga
     9061 gcgagtgaag ctggacttga gtttcaaact gttgaaaatt ttcagtcctt gcacgggaaa
     9121 ggtgtttcag ggcgaatcaa tggaaaacaa gttttacttg gaaatgctaa aatgctggat
     9181 ggcatggata tttctaatac ttatcaagat aaactagaag aactagaaaa agaagctaag
     9241 acagttgtgt tcttagctgt tgacaatgaa atcaaaggct tgcttgcttt gcaagatatt
     9301 cctaaggaaa atgctaagct agccatcagt cagctaaaaa aacgtggtct ccgaacagtc
     9361 atgctgacag gagacaatgc tggtgtggcg cgtgctattg cagatcaaat cggaattgaa
     9421 gaggtcattg caggcgtctt gccagaagaa aaagcccatg aaatccataa actgcaacag
     9481 tcagggaaag tagcctttgt tggggacggt atcaatgacg ctcctgccct tagtgtagca
     9541 gatgtgggaa ttgctatggg tgctggaaca gatatcgcca tcgagtcagc agatttggtg
     9601 ttgacaacca ataatatttt aggagtggtt cgtgcctttg atatgagtaa gaaaaccttt
     9661 catcgaattc tactcaatct tttctgggct tttatctaca atgttgtcgg aattccgatt
     9721 gcagcaggag tcttttcagg tgttggactg gctctcaacc cagaattggc aggtctagcc
     9781 atggccttta gttctgtatc tgttctgacc agttcccttc tgttaaattt tagtaaaata
     9841 gactaaaagt aatgactaga tttctttgtt ataaaacaga aatgacaaca ctttcaaaac
     9901 tgtattagaa tagagaatag agagttttga gcagattttt agaaaagtca gcataaatat
     9961 gatacagtgg aatagtaaaa atttggagaa cgtttccaat tctatgtaat cgtattctcc
    10021 aagtctaaaa aaattgaagg agagttatca ttatgactca agggaaaatt actgcatctg
    10081 cagcaatgct taacgtattg aaaacatggg gcgtagatac aatctacggt atcccatcag
    10141 gaacactcag ctcattgatg gatgctttgg ctgaagacaa agatatccgt ttcttacaag
    10201 ttcgccacga agagacaggt gctcttgcag cggttatgca agctaaattc ggcggctcaa
    10261 tcggggttgc agttggttca ggtggtccag gtgcgactca cttgattaac ggtgtttacg
    10321 atgcagctat ggataacact ccattcctag cgatccttgg atcacgtcca gttaacgaat
    10381 tgaacatgga tgctttccaa gagcttaatc aaaacccaat gtacaacggt atcgctgttt
    10441 acaacaaacg tgtagcttac gctgagcaat tgccaaaagt aattgacgaa gcctgccgtg
    10501 ctgcagtttc taaaaaaggt ccagctgttg ttgaaattcc agtaaacttc ggtttccaag
    10561 aaatcgatga aaactcatac tacggttcag gttcatacga acgctcgttc atcgctcctg
    10621 ctttgaacga agttgaaatc gacaaagctg ttgaaatctt gaacaatgct gaacgcccag
    10681 ttatctatgc tggatttggt ggtgttaaag ctggtgaagt gattactgaa ttgtcacgta
    10741 aaatcaaagc accaatcatc acaactggta aaaactttga agctttcgaa tggaactatg
    10801 aaggtttgac aggttctgct taccgtgttg gttggaaacc agccaacgaa gtggtctttg
    10861 aagcagacac agttcttttc cttggttcaa acttcccatt cgctgaagtt tacgaagcat
    10921 tcaagaacac tgaaaaattt atccaagtcg atatcgaccc ttacaaactt ggtaaacgtc
    10981 atgctcttga cgcttcaatc cttggtgatg ctggtcaagc agctaaagct atccttgaca
    11041 aagtaaaccc agttgaatca actccatggt ggcgtgcaaa cgttaagaac aaccaaaact
    11101 ggcgtgatta catgaacaaa ctcgaaggta aaactgaggg tgaattgcaa ttgtatcaag
    11161 tttacaatgc aatcaacaaa catgctgatc aagacgctat ctactcaatc gacgtaggta
    11221 acactactca aacatctact cgtcaccttc acatgacacc taagaacatg tggcgtacat
    11281 ctccactctt tgcgacaatg ggtattgccc ttcctggtgg tatcgctgct aagaaagaca
    11341 atccagatcg ccaagtatgg aacatcatgg gtgacggagc attcaacatg tgctacccag
    11401 acgttatcac aaacgttcaa tacgaccttc cagttatcaa ccttgtcttc tcaaatgttg
    11461 agtacggctt catcaagaac aaatacgaag atacaaacaa acacttgttt ggtgtagact
    11521 tcacaaacgc tgactacgct aaaattgcgg aagctcaagg agctgttgga ttcacagttg
    11581 accgtatcga agacatcgat gcagttgttg cagaagctgt taaattgaac aaagaaggta
    11641 aaactgttgt catcgatgct cgcatcactc aacaccgtcc acttccagta gaagtacttg
    11701 aattggatcc aaaacttcac tcagaagaag ctatcaaagc cttcaaggaa aaatacgaag
    11761 cagaagaact cgtaccattc cgtctcttct tggaagaaga aggattgcaa tcacgcgcaa
    11821 ttaaataatt cctctcgtcg aaaatcaaat atgaaacttg tagactttat tctttgattt
    11881 tcatagagca gaactttaaa agatcggagc aatccggtct ttttatggag gagagtaaat
    11941 gaatttaaat caattagata ttatcgtttc aaatgttccc caagtctgtg ctgacttgga
    12001 gcatatcttg gataaaaagg cagattatgc tgatgatggt tttgctcagt ttacgattgg
    12061 tagtcactgc cttatgttgt cacaaaatca tttggttcct ttggaaaact ttcagtcagg
    12121 aatcattatt catatcgagg ttgaggatgt agaccagaac tacaaacggt tgaacgagct
    12181 tggtataaag gttttacacg gaccaactgt aaccgattgg ggaacagagt ccttattagt
    12241 tcaaggacct gctggtctag tgcttgattt ttatcgtatg aaataggtcg cgtagtcatt
    12301 tgacgttaac cttagctatt tttaaaatag aaattgagaa tatgaactat tgaaagatcg
    12361 gagcaatccg gtctttttat ataaagaaat tgcatataat actcatctgc tttcaaaaag
    12421 cattctagtc catctccgat taacgatgga ctttatcacc tccttctcca atccttgtat
    12481 gacatcttgg agttgattca tgacatcttc caaagttcga aaggctttat tcttaaatcc
    12541 acgtttacga atctctttcc acacttgttc aatggggttc atctctggtg tgtatggagg
    12601 aataaatgca aagccaatat tagtcggaat ctttaaggta cttgatttat gccatatagc
    12661 attgtccata acgagtaaaa aataatcata tggataagct tgtgaaagct cttctaaaaa
    12721 gacgttcatc cactcagtat tacatccacc agctcttaag aaaaatgatt cgcctgtata
    12781 ggcatcaaca gctccataac aatagcgaaa ttctcgtata tagtgactat ggatatgtgg
    12841 acctactcct attggagacc aacaagatcc cagtttactg attctaccga aaccagcctc
    12901 atcttggtac atcaagtgaa ccttacgaaa acgtctactg gttttaaatc gctttctttt
    12961 cttcttgaat tgagatttta tttttagacg cgacaatggt ttgagcgtct gctttcttag
    13021 gatgttctgg acgtggcgta atatttcgcc aaccatggcg cttcaacagt tgatagaagg
    13081 catcacgtgt gtaggaacga cctaactcct ttttataagc ctgaaataag gca
//
LOCUS       DAVIME010000058        12704 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVIME010000058 DAVIME010000000
VERSION     DAVIME010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.058"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(259..987)
                     /locus_tag="VV588_001866"
                     /pseudo
     CDS             complement(259..987)
                     /locus_tag="VV588_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(1222..1533)
                     /locus_tag="VV588_001867"
     CDS             complement(1222..1533)
                     /locus_tag="VV588_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084155.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1548..2834)
                     /locus_tag="VV588_001868"
     CDS             complement(1548..2834)
                     /locus_tag="VV588_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU7084156.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     TLIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            3458..3580
                     /locus_tag="VV588_001869"
     CDS             3458..3580
                     /locus_tag="VV588_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU7084157.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAG"
     gene            3650..4015
                     /locus_tag="VV588_001870"
     CDS             3650..4015
                     /locus_tag="VV588_001870"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU7084158.1"
                     /translation="MPNSESTKPKTFEIDCLVGKKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            4012..5202
                     /locus_tag="VV588_001871"
     CDS             4012..5202
                     /locus_tag="VV588_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU7084159.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGSDM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(5717..6709)
                     /locus_tag="VV588_001872"
     CDS             complement(5717..6709)
                     /locus_tag="VV588_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7084160.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            6869..8623
                     /locus_tag="VV588_001873"
     CDS             6869..8623
                     /locus_tag="VV588_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084161.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            8607..10328
                     /locus_tag="VV588_001874"
     CDS             8607..10328
                     /locus_tag="VV588_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084162.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            10339..10968
                     /locus_tag="VV588_001875"
     CDS             10339..10968
                     /locus_tag="VV588_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU7084163.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYIVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            10869..11426
                     /locus_tag="VV588_001876"
     CDS             10869..11426
                     /locus_tag="VV588_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU7084164.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            11414..>12704
                     /locus_tag="VV588_001877"
     CDS             11414..>12704
                     /locus_tag="VV588_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084165.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTM"
BASE COUNT         4510 a         1946 c         2175 g         4073 t
ORIGIN      
        1 ttgtgaaatt ttattaacaa aaaactctat acaacaaaat aatagagagt tttctgctta
       61 ttaatttttt tcaaaatatc taagacatcg cttctttgtt taatttgata ggctttgata
      121 cctaagctcc gactttatca cttaaaaaat aaaaaagaca gctaatctct tgcgcatcag
      181 gggatttcgc cattctttaa tctcgtttaa gtgttgtata tggagctttg cataattttt
      241 taaaactaaa caactacatt aagcacgaac tgtgacgctg gttccatctt ccttataaag
      301 attgataagc ccctctttaa gagctcgaac catgtctcca gcttgaacag gttgtgggac
      361 tttaatagtc aatagttcca ttggatttgg agcgcggtcg attttatttc ctttggcatc
      421 atgcaaatct tcaatatagg tttcaaaatg acggaaacct ggaccataaa actcaacttg
      481 gtccccttcg ttaatgacgt tccgttgacg aatggttgct gtttgtgtcg catcatcata
      541 agaaaccact tcagcgacaa acttgtactc aggaatttta cgacgagcac caaacaactg
      601 ctcattttca gatggtgtac catagtaaaa tcctgtaacc agttcacgtt gggcaacctt
      661 ccacatctcg tccaccaagt cttgtttgat agcttcaaac ttttcaggac tttcaagata
      721 ggcatccaca gccgccttgt agcagttggt tactgttgat acgtagtgaa tagacttcat
      781 acgtccttcg atttttagac tgtccacacc attttcaatc atatctggaa tgtggtcaat
      841 catagacatg tcaacggctg acattgaaaa ttcttctgga atctcaccct gcaaactctt
      901 acgttctttc ccaaatgcca tatcgtaaag gtcgtatttc caacggcatg actgagaaca
      961 tccaccacgg ttggcatcac gcatactcta gacgcaattc taatctttta gactttgcat
     1021 aataactgtt aaacagttga aaattaaccc agttttaaca agtagtcaaa ataccagata
     1081 aaggaaaaaa gtctttaaaa tcttaaaaac gcatagtatc aggtattgaa caatcttgat
     1141 attatgcgtt ttattgtggg aagatttact tcattttctc ttggaattga gttttctcct
     1201 acttcaaaac tagatgattt gctatttaaa atagcgttcc ttatgatttt ggcaacctgg
     1261 attaaagcga gaaaaacaaa aggggcaact taagctttct ttatattgct tatatgttag
     1321 tagttttaga caaacaccac ataaaatagg cttatcctgt atcaaagata agggatacgg
     1381 ctcaaaaggg tgattttcta atgaatcatg acaccgataa caagcataat actttttaca
     1441 atcatagcat tgtaaagcaa taatatccag cttgctatgg taatgaatgc atcttgtttg
     1501 cttatccact aagaaaccct gtgcctctat catttccttt tcctttctta agctcgaact
     1561 gtgacgctgg ttccatcttc cttataaaga ttgatgagtc cttcttttaa tgcacgaacc
     1621 atgtctcctg attgaacggg ttgaggcacc ttaatagtca atagttccat tggatttgga
     1681 gcgcggtcga ttttattgcc tttggcatca tgcaaatctt caatataggt ttcaaaatga
     1741 cggaaacctg gaccataaaa ctcaacttgg tccccttcgt taatgacatt tcgttgacga
     1801 attgttgctg tttgtgccgc atcatcataa gaaaccactt cagcgacaaa cttgtactca
     1861 ggaattttac ggcgagcacc aaacaactgc tcattttcag atggtgtacc atagtaaaat
     1921 cctgtagcca gttcacgttg ggcaaccttc cacatctcgt ccaccaagtc ttgtttgata
     1981 gcttcaaact tttcaggact ttcaagatag gcatccacag ccgccttgta gcagttggtt
     2041 actgttgata cgtagtgaat agacttcata cgtccttcga tttttagact gtccacacca
     2101 ttttcaatca tatctggaat gtggtcaatc atagacatgt caacggctga cattgaaaat
     2161 tcttctggaa tctcaccctg caaactctta cgttctttcc caaatggcat gtcgtaaagg
     2221 tcgtatttcc aacggcatga ctgagaacat ccaccacggt tggcatcacg catactcatg
     2281 tggtttgaaa gagtacaacg tccagagtat gaaatacaca tagctccatg gacaaaggct
     2341 tcaatttcaa catctgtacg tttgcggatt tcagctaatt cttccattga aacctcacgc
     2401 gctaaaacga cacgagtcaa gcctagctct ttccagaact caagggtttc atagttagtg
     2461 gcactggctt gggtagaaag gtggatttca aggcctggtg cttcagtcgc tgcaatcata
     2521 atcaaggttg ggtcagatac gataactgct gcaatcccga tatcacgcag tttacggaac
     2581 cactcaccag caccagcttc atttccttcg tgcataacca tattagccgc tacatagacc
     2641 ttggcaccat acttggccgc aaactgcacg ccttcttcca tctgttcgaa agtaaagttt
     2701 cccgcacggc tacgaagacc ataggcctga ccaccgataa agacagcatc tgctccatac
     2761 tgaacagcta cctttagctt ctctaaagtc cctgcaggtg ataaaacctc aggacgtttt
     2821 aatgtttttg tcataatttc tcctatttgc aatataaaag tttgacattt ttccttctca
     2881 ttttatagta aataaaggat aaaatcaagc ctagacggat tgttttgaca attctaatct
     2941 tttagacttt gcataataac tgttaaacag tcgaaaatta tcccagtttt aacaagtagt
     3001 caaaaagtct agaaaagtaa aaaccagtat ccaaagatac tgactcgtaa aaatacataa
     3061 attagtcctt agatgactac tcccactctg ttgctcctat aatggaaaag gattgataca
     3121 gtctagaata tcgctttttt atttattatt ctgatataaa actgttagaa ttgatttttt
     3181 gttttatacc caaatatgaa tagagacgta gctaataagt tgaataacat atttggaaaa
     3241 atgagaaata gcaatattac tagaactttt agaaacaatc aatatttaaa aagaaaaaag
     3301 ctcaaagaat ttattaaacc atgttataat agatatagct ataattttat ttataacaag
     3361 aggatagaaa tgaccgaatt agaaagaaaa aatcgaaaaa ttagctaaga aatattctga
     3421 taacttaaac atcaaagttc aagagagagt tcgtgaaatg gcaaatgata ataagagcca
     3481 ttatttgata tacagagttt taggtatttc atttgaagaa ggagaaaata tcgatttgta
     3541 tcaaaataaa ggtcgttttt tatacaaata tgctggttaa tttttagaag aagctgcagt
     3601 actatccttt aacgaaaaat ttggtacaga aaatacttaa aaagttaaca ttcctaattc
     3661 tgaaagtaca aaacctaaga cttttgaaat tgattgttta gtcggaaaaa aacacgcata
     3721 cgaaataaaa tggtgggatg caactacaga tggagaccat ataactaaag aacacactag
     3781 aataaaagtt attcataaca aaggatatat accaattcgg ttaatgttct actatccaaa
     3841 tagaactcaa gctataaaaa ttcagcaaac tttagaaaca ttgtataacg gtattggagg
     3901 gaaatattat tatggagatt ctgcctggga acatttaaga gcagtgaccg gtattgattt
     3961 acttagtatt ctaacagata ttgcaaataa aaaaacaggg gtaaaatcaa aatgacagta
     4021 ttaaaaggag ataacttaga aatattaaaa actattgaat cctcaagtat tgatttaatc
     4081 tatatggacc ctcctttctt tacacagaaa acccaaaaat tatctaataa caaaaatatt
     4141 atgtattcat tcgaagatac gtggacttcg attgaggatt acaaagaatt tttgtctgta
     4201 agattagaag aatgcaaaag agtgctaaaa aatagtggca gcattttcgt tcattgtgat
     4261 aaaattgcaa atcatcatat tagattaatt ttagataata tctttggatc agatatgttt
     4321 caaagcgaaa ttatatggaa ctataaacgg tggtctaatt caaaaaaggg attattgaac
     4381 aatcatcaaa acatttactt ttattcaaag tcaaaagatt ttaaatttaa tacaattttt
     4441 acagagtatt cttctactac aaatatcgac caaatactag tggaacgaaa acgagatgga
     4501 aactctaaaa ctatatataa agttgataat aatggtaact atattctagc aaaagagaaa
     4561 aatggagttc ccctttcaga tgtttggaat ataccatttc ttaatccaaa agctaaagaa
     4621 agagtaggtt atcctacaca aaaacctatt ctgttattag aacaaattat aaagattgct
     4681 actgataaaa atgatatagt tttagacccg ttctgtggaa gtggaactac tttagtagcc
     4741 tccaagattt tgaatagaaa ttatatgggg attgatttat ctgaggaagc tatcaatata
     4801 actcagcaac gtctggaaaa tgttataaaa acaagttcaa atttattgaa taaaggaatc
     4861 gaagcatata gaaccaaaac tgaggaagag gaaaacattc ttaaattatt acaggcaaaa
     4921 attgttcaaa gaaataaagg aattgatggt tttttaccta aacattttca aaaaaaaccg
     4981 atacctataa aaattcaaaa aaataatgaa tgtctgaatg agagtatctc tttattacag
     5041 aatgctataa actccaaaaa acttgatttt ggagtagtta taaaaactca ttcagataat
     5101 ttattatttg attttgatac gattcctgaa aatataatag tagttgacca ttttgaactt
     5161 acaatcgaaa aatggttaag taaaagtcaa cagttactat agtttgcaaa ttatttacag
     5221 aaagaacaaa aatgctctga aacactgatt tcaaagcatt tttttgttag tttaaaatta
     5281 ctcccattct tcttttccaa acgtacaata tatccaaaac cattcaaaat actagattct
     5341 attttttata atatcactaa atccacctaa ttataggacg ttttcagatt tttagtcccg
     5401 tcccagtccc agtaccggag aaatattgtt ttaatataat atctcttttt gtcttctaag
     5461 ctcttaaaag caaaagaaca agtaaagagt caagacaagg ataaaaagtc catattaggg
     5521 caaataaaaa gctttaagac agatgacaaa tctaagtcaa ataagaaaga ccatagcaaa
     5581 ggtgcagaga gataaatatt ggcggtcttc ggactgcctt tattttttta tccatttttc
     5641 aaatcaaatt tattcagact atatatgcac atatacactt aaattcatat aaaaacatgg
     5701 cttgtaaaaa attactttaa tcacaataat cgcatttaaa attgtgatgt ttgcaagcta
     5761 aattacggac ttcacttgga agttttccct tgtatctttt ataatagata gaaaatttgc
     5821 tggcagatga atatccaaca gattctgcta tctcttttat aggtagttca gtgtttaaaa
     5881 gaagagtttc agctacattc attctttttc tttgagtgta ctctgtaatg ctttgacaat
     5941 atttttcctt aaataaattt tttaatttag taccactcat tttagatatt ttttcaagcg
     6001 tgccttgatt tacattcgtt gcaaaatgat catctaagaa tcttgctaca tcttcaagtg
     6061 ctttatcatc atcaatttca attttatatt tttttctatt taagtatgtg tcaattacta
     6121 tacttatcca ttcatttgcc tttgctttaa agaaaaaatc agcggcagga gcgtccatct
     6181 tacaatttaa tatttccatt gccactcttt ctaaggcctt tgtaagtatt atttgattcg
     6241 gttgaagcaa ggttgaataa aaagattctg gattaatgtt aatagatgct aaatgttttt
     6301 ctattagctc ttttttaaaa ccaatggaaa cagcaagata acaacaattc tcgtgtaata
     6361 aaaaaacaaa atcatctttt atattatcaa aatcaaaagt acatagagag tttgcggtaa
     6421 tagtttgata cggattaaac ttttctccgt ttgcactgac aatgtaactt gaataaattg
     6481 aaacatagtc tgacatacta taagtgctat tttgaactac ttcctctttg atataaaaat
     6541 catgtatatc gataatgaag ctgcctcctt cataaaacca atataggcct tctgcataag
     6601 ttgaattctc ttttttccaa caaaatgtat gacctgcact tgaatacttc tcattgtttt
     6661 tacattcatc tactttcata taatctttta caaaatcata atatgacata acacactatc
     6721 ccttttagac aatattccaa ttagccttat taattcaaaa ctattgtatt agtaattata
     6781 acagatgtat aatagaaaag caatgataga tattatcaat taagcgaatt tatatctaaa
     6841 agggatatta aagaaaggag atatgcttat gaagatttac aaaaaactat ttgcttatgt
     6901 ccaagataag aaatatcttg gggttttggc cataattttt tctgctatat ctgctctact
     6961 tacagtatat ggatattatt taatctacaa atttctagat aagttaataa ttaattcaaa
     7021 tttatccggt gcagagagta tagcattaaa atctgttatt acactaacaa gtggagcgat
     7081 attttatttt gtctcaggaa tgttttcaca tatcttggga ttcaggcttg aaacaaattt
     7141 aagaaaaagg ggaatcgatg gtctggaaaa agcaagtttt aggttctttg acttaaatcc
     7201 atctggtcaa ataagaaaga tcatagatga taatgcagca caaactcatc aggtggtagc
     7261 acacatgatt cccgatagtt ctcaggcaat aatcacaccc gtacttgtac ttgcacttgg
     7321 ctttatagta agtataagag ttggcataat tttgcttgct cttactataa ttggtggctt
     7381 aattttaggg gcgatgatgg gcgagcaaga atttatgaag atataccaag aatccctatc
     7441 taaactaagt gctgaaactg ttgagtacgt gagaggaatg caagttgtaa aaatatttaa
     7501 agcaaatgta gagtcattta aaagctttta caaggctata aaagattact caaagtatgc
     7561 ttatgattat tccctatctt gtaaaaggcc ttatgttttg tatcaatggt tattttttgg
     7621 actgattgca attttaatta ttcctatagt ttattttatg actagcttag ctagcgcaaa
     7681 ggtgatttta cttgagctta tcatgatttt atttttatca ggagttctct ttgtttcatt
     7741 catgagaatg atgtggtact ccatgtatat ttctcaagga aattatgcag tagatacttt
     7801 agaggcgctt tacgaagata tgcaaaaaga caaattagtg catggtaatg tcaataattt
     7861 taaaaactat aatatagaat ttgagaatgt tagctttgct tataatgata aagctgtcat
     7921 tgaaaattta tcctttaatt tagaagaagg aaagtcctac gcacttgtcg gttcatctgg
     7981 atcaggcaaa tcaacagtag caaaacttat atcaggtttt tacaatgtta atgaaggaag
     8041 cataaagata ggcgggatag caataagtga atattctgac gaagccttaa ttaaagccat
     8101 ttcctttgtt tttcaagatt caaaattatt caagaagagc atttatgata atgtagcttt
     8161 agctaataaa gatgcgacga aagatgacgt tatgagagcc ttaaaattag caggatgcga
     8221 tttaatatta gacaaattcc cagaaagaga aaatacaatc ataggctcaa aaggtgttta
     8281 tttatccggt ggagaaaaac aaagaattgc aattgctaga gcaattttaa aggattccaa
     8341 aattattatt atggatgaag catcagcatc tattgaccca gataacgagt ttgaattgca
     8401 aaaagctttt aaaaatctta tgaaggataa aacagttatc atgattgcac acaggctatc
     8461 tacaattaaa gaccttgatg aaattattgt catggatagt ggaaaaatta tagaaagagg
     8521 gtctgacaaa gaattaatgt caaaagatac aaggtataag agcctgcaag agatgtttaa
     8581 cagtgcgaat gaatggaggg tttcaaatga aagagtttta taaaaaaaga tttgctctta
     8641 cagatggagg agcaagaaat ttaagtaaag caacactggc ttcatttttc gtttattgta
     8701 taaacatgct tcctgccata ttacttatga tttttgctca ggaagttttg gaaaatatgg
     8761 gcaaaagcaa tggcttttat atagtattct cagttttgac tttgatagca atgtatattt
     8821 tgctttctat cgaatacgat aaattatata acacaaccta tcaagaaagt gcagatttaa
     8881 gaataaggac agcggagaat ttatcaaaat tacctctatc ttacttttct aaacatgaca
     8941 tttccgacat ttcacaaaca atcatggctg atattgaagg catagagcat gcaatgagcc
     9001 actcaatacc aaaggtgggc ggcatggtac tgtttttccc attaatatct gtaatgatgc
     9061 tagcgggcaa tgtcaagatg ggtttagctg taattattcc atctatttta agctttatat
     9121 ttataccttt atctaaaaaa tatcaggtta atggacagaa tagatattat gatgtcttaa
     9181 gaaaaaactc agaaagcttt caagaaaata tcgaaatgca aatggagatt aaagcatata
     9241 atttatcgaa ggatattaaa gatgacttat ataaaaaaat ggaagatagt gagagagtac
     9301 acttaaaggc ggaagtaact acaattttaa ctttgtctat atcttcaata tttagcttta
     9361 tatctcttgc tgttgtgata tttgtcggcg taaatctaat tattaataaa gagataaatt
     9421 ctctctacct tataggatat ttactagctg ctatgaagat aaaagactct ttagatgcat
     9481 ctaaagaggg cttgatggaa atattttatt tatcgcccaa aatagaaaga ttaaaagaaa
     9541 ttcaaaatca agatttacaa gaaggcgatg actatagctt aaaaaaattt gatattgatc
     9601 taaaagatgt tgagtttgcc tacaataaag acgcaaaagt tttaaatggt gtaagtttta
     9661 aagctaagca gggagaggtc actgctttgg taggtgcaag tggctgcggt aaaacaacta
     9721 tcttgaaact tatatcaaga ctttatgatt atgacaaggg acaaatctta atcgatggca
     9781 aagatataaa agaaatatca acagaatctc tttttgataa ggtctctata gttttccaag
     9841 atgtggttct ctttaatcaa agcgttatgg aaaatattag aatcggaaag caagatgcaa
     9901 gtgacgaaga ggttaaaaga gcagcaaaac ttgcaaattg cacagatttt atagaaaaaa
     9961 tggataaagg tttcgataca gttattggtg agaacggagc tgagctatca ggaggagaaa
    10021 gacaaagatt atcaatagcc agagccttct taaaagatgc gccgatattg atcttagatg
    10081 agataacagc aagccttgat gttaacaacg agaaaaagat tcaagagtct ttaaataatt
    10141 tagttaaaga taaaactgtt gtaatcattt cacatagaat gaaatccata gaaaatgcag
    10201 acaagatagt agttcttcaa aacggaagag tagaaagcga aggtaagcat gaagagcttt
    10261 tacaaaaatc aaaaatttac aaaaatttaa tagaaaagac aaaaatggca gaagaattta
    10321 tttattagga ggactacaat ggataataaa aaattaaaag taaaagattt agtaagtatc
    10381 ggtgtttttg gcgtaattta ttttgccttc atgtttggag ttggtatgat gggcttgatt
    10441 ccaatattgt tcttaatata cccgacagta ttagccatag ttgcaggaac tgttgttatg
    10501 ttatttatgg ctaaggttca aaagccatgg gcactattta tatttggtat gatatcacca
    10561 cttgtgatgt ttgcagctgg tcatacctac atagttgtgg ttttatcact tatagtaatg
    10621 ataatagcag aattaattag aaagattggt aattataatt catttaaata caatatgctt
    10681 tcttatgcaa tcttcagcac atggatatgt agctctttaa tgcaaatgct tttagcaaaa
    10741 gaaaaatata tggagtggtc tttgatgacg atgggaaaag attatgttga tgtattagaa
    10801 aagttaataa cttatcctca catggcttta gtagccttag gtgctttctt aggaggaatt
    10861 cttggagcat atataggcaa ggctctattg aaaaaacact tttcaaatgg attatattgt
    10921 gtgggatact ttactccttg cctaatttta tggtgttatc tgaattaaac cctatagtta
    10981 agatgttttt gagtatacct attgttatta gaatgtttat tttaccattt atggcagcaa
    11041 gctttatgat aaagacctcg gatgtaggcg caataatttc atcgatggat aagcttaaga
    11101 tttcaaagaa tgtatccata cctattgcgg ttatgtttag attcttccca tcttttaagg
    11161 aggagaagaa aaacatcaaa atggctatga gagtaagagg gataaatttt aaaaacccag
    11221 tcaaatatct tgaatatgtt tctgtgccac tactcattat atcatctaat atatcagatg
    11281 acattgcaaa agcggcagaa acaaaggcaa tagaaaatcc aattgccaag accagataca
    11341 ttcgcgtaaa gatacagcta attgattttg tttatgtttt agcggttgct ggacttattg
    11401 tgggaggatt aatatggttg aaataaaaaa tttaagtctt gattatggtg aagagcatat
    11461 attagatgat atatcactat ccatagccga gggagagtgc gtgctattta caggaaaaag
    11521 tggaaatggt aagtcatctt taataaattc aatcaatgga ctagctgtaa ggtatgacaa
    11581 cgcaaagaca aagggcgaaa taattattga tggtaagaat ataaaaaatt tggaacttta
    11641 tcaaatctca atgcttgttt caactgtttt tcaaaatcct aagacatatt tttttaatgt
    11701 caatacgaca ttagaattat tattttattt ggaaaatatc ggtcttgcaa gagaagagat
    11761 ggacaggcgt ttgaaggata tgcttgagat attcccgata aaaaatcttt taaacagaaa
    11821 tatatttaat ctatccggcg gtgaaaaaca aattctttgc attgcagctt cttatatagc
    11881 aggtacaaag attatagtta tggatgagcc ttcatcgaat ttagatatta aaagcataag
    11941 tgttttggca aagatgctaa agatattaaa agagaaaggc ataagcataa ttgttgcaga
    12001 gcatagaatt tattatttga tggacatagt tgaccgtgta tttttaatag ataaaggaaa
    12061 gcttaaaaaa acttatacta gaagtgaatt tttaaagcta gataaaaatg aattaaatgc
    12121 tttaagttta agagataaag aattaagtaa attaaaagtt ccttatttaa aagaaggtgg
    12181 agagtatcag ataaaaaatc ttagctacaa atttactgat gatgagtgtt taagcttaaa
    12241 agatatttcg ttcaagcttg ggaaaattta tggcataata ggatccaacg gacgaggaaa
    12301 atcaacgctt ttaagatgtt taataggtct tgagaaaaaa tcaaaagaag aaatttattt
    12361 taagggagag aagctatcta aaaaagaaag actcaaaaac tcttcacttg ttatgcaaga
    12421 tgtaaatcat caattattca cagatgaagt attcaacgag cttagattag gagtaaagaa
    12481 ttttgatgaa gaaaaggcga aaatcatctt aaaagattta ggcctggacg aatttattga
    12541 aaggcatccg atgagtttat caggagggca aaagcaaagg cttgcaatag catctgttat
    12601 gtgcaagaat tctccatttg tcttttttga cgaaccttca agtggtatgg attattccaa
    12661 tatgataaaa atatctgaac tgattaataa gtataaaacc atgg
//
LOCUS       DAVIME010000059        11511 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVIME010000059 DAVIME010000000
VERSION     DAVIME010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.059"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            44..6118
                     /locus_tag="VV588_001878"
     CDS             44..6118
                     /locus_tag="VV588_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU7084166.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVSDKG
                     VPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPV
                     EKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSP
                     DTSSENTGEVSNKPSDSTTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSN
                     QETEKPVQPAEETQTNSGKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSG
                     NTTSENGQTEPEPSNGNSTEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLEL
                     RNVSDLELYSLSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKND
                     KILYKITAKVEKLQQEIESRYKDNFPFYLAKKGTEETTNFTSFSNLVKAINQNLSGTY
                     HLGASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEI
                     NLITPPIVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVK
                     ENSILYQKELLSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANL
                     AEYSIGDSGLLYTPNQFLYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELY
                     LEEQFTKTKEHLAENLKKLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERW
                     YNFSYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLAS
                     HHGTTDLFSTLENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLN
                     SFVEKSAHETAERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVA
                     DFDSPNPAMKHFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVL
                     DPTTRFKDATDLQKYVHNMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDP
                     ADGNDVYATNVVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSGEKGTPGDLMGRRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTK
                     TINNVDELQKLMDEAVLQDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFR
                     RSIFENKK"
     gene            6162..11435
                     /locus_tag="VV588_001879"
     CDS             6162..11435
                     /locus_tag="VV588_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU7084167.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVN
                     DIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVGE
                     DGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTKERPKEKTAPVLTLTKVT
                     EDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDLFKD
                     YKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMN
                     EKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTK
                     VRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVD
                     GDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTI
                     KGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVG
                     ENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVES
                     PVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGV
                     SEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEY
                     KSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQF
                     VTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQ
                     LIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLD
                     KLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNL
                     MMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNM
                     RLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTL
                     KNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPS
                     VRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNW
                     NMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTD
                     VEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMK
                     NYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRD
                     LNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNT
                     SQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSN
                     NQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGN
                     YSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
BASE COUNT         4171 a         1875 c         2359 g         3106 t
ORIGIN      
        1 aaggtctttg taacatatat aaattttatt tcaaggagga ataatggaaa agtattttgg
       61 tgaaaaacaa gagcgttttt catttagaaa attatcagta ggacttgtat ctgcaacgat
      121 ttcaagttta ttttttatgt ctgtattagc tagttcatct gtggatgctc aagaaactgc
      181 gggagttcac tataaatatg tggcagattc agagctatca tcagaagaaa agaagcagct
      241 tgtctatgat attccgacat acgtggagaa tgatgatgaa acttattatc ttgtttataa
      301 gttaaattct caaaatcaac tggcggaatt accaaatact ggaagcaaga atgagaggca
      361 agccctagtt gctggtgcta gcttagctgc tctgggaatt ttaatttttg ctgtttccaa
      421 gaaaaaggtt aagaataaaa cggtattaca tttagtattg gttgcgggaa taggaaatgg
      481 tgtcttagtt tcagtccatg ctttagaaaa tcatcttttg ctaaattaca atacggacta
      541 tgaattgacc tctggagaaa aattacctct tcctaaagag atttcaggtt acacttatat
      601 tggatatatc aaagagggaa aaacgacttc tgattttgaa gtaagtaatc aagaaaaatc
      661 agcagccact cctacaaaac aacaaaaggt ggattataat gttacaccaa attttgtaga
      721 ccatccatca acagtacaag ctattcagga acaaacacct gtttcttcaa ctaagccgac
      781 agaagttcaa gtagttgaaa aacctttctc tactgaatta atcaatccaa gaaaagaaga
      841 gaaacaatct tcagattctc aagaacaatt agccgaacat aagaatctag aaacgaagaa
      901 agaggagaag atttctccaa aagaaaagac tggggtaaat acattaaatc cacaggatga
      961 agttttatca ggtcaattga acaaacctga actcttatat cgtgaggaaa ctatagagac
     1021 aaaaatagat tttcaagaag aaattcaaga aaatcctgat ttagctgaag gaactgtaag
     1081 agtaaaacaa gaaggtaaat taggtaagaa agttgaaatc gtcagaatat tctctgtaaa
     1141 caaggaagaa gtttcgcgag aaattgtttc aacttcaacg actgcgccta gtccaagaat
     1201 agtcgaaaaa ggtactaaaa aaactcaagt tataaaggaa caacctgaga ctggtgtaga
     1261 acataaggac gtacagtctg gagctattgt tgaacccgca attcagcctg agttgcccga
     1321 agctgtagta agtgacaaag gcgaaccaga agttcaacct acattacccg aagcagttgt
     1381 aagcgataaa ggcgtaccag aagttcaacc tgaattaccc gaagcagttg taagcgataa
     1441 aggcgtacca gaagttcagc ctgaattacc cgaagcagtt gtaagtgata aaggtgaacc
     1501 agagcaggta gcaccattgc cagaatataa ggggaatatt gagcaagtaa aacctgaaac
     1561 tccggttgag aagaccaaag aacagggtcc agaaaaaacg gaagaagttc cagtaaaacc
     1621 aacagaagaa acaccagtaa atccaaatga aggtactaca gaaggaacct caattcaagg
     1681 agcagaaaat ccagttcaac ctgcagaaga atcaacaacg aattcagaga aagtatcacc
     1741 agatacatct agcgaaaata ctggggaagt atccaataaa cctagtgatt cgacaacctc
     1801 agttggagaa tcaaataaac cagaacataa tgactctaaa aatgaaaatt cagaaaaaac
     1861 tgtagaagaa gttccggtaa atccaaatga aggcacagta gaagggacct caaatcaaga
     1921 aacagaaaaa ccagttcaac ctgcagaaga aacacaaaca aactctggga aaatagctaa
     1981 cgaaaatact ggagaagtat ccaataaacc tagtgattca aaaccaccag ttgaagaatc
     2041 aaatcaacca gaaaaaaacg gaactgcaac aaaaccagaa aattcaggta atacaacatc
     2101 agagaatgga caaacagaac cagaaccatc aaacggaaat tcaactgagg atgtttcaac
     2161 caaatcaaac acatccaatt caaatggaaa cgaagaaatt aaacaagaaa atgaactaga
     2221 ccccgataaa aaggtagaag atccagagaa aacacttgaa ttaagaaatg tttccgacct
     2281 agagttatac agtttgtcaa atggtactta taaacaacac atttcgttag agcaagttcc
     2341 aagcaatcca aatagctact ttgttaaagt gaaatcttct tcattcaaag atgtatacct
     2401 accagtagca tcaatatcag aggaaagaaa aaatgataaa atcctttata aaatcacagc
     2461 aaaagtagag aagcttcagc aggagataga aagcagatat aaagataatt ttcccttcta
     2521 tctagctaag aagggaacag aagaaacaac aaactttact tcctttagta atctggtcaa
     2581 agctataaac caaaatctct ctggaaccta tcatttagga gctagcctga atgctaacga
     2641 agtggagctt agtactgatg ataaatccta tatcaaggga acctttactg gtcagttgat
     2701 tggtgaaaaa gatggtaagc attatgctat ttacaacttg aaaaagcctc tttttgaaaa
     2761 cttgagtggt gctacagtag aaaaactgag tctaaaaaat gttgctattt cagggaaaaa
     2821 tgatattggt tcactggcaa atgaagctac gaatggcaca aagattaaac aagttcatgt
     2881 tgatggtgtt ctggctggag aacgtggtgt cggtggtttg ttggctaagg cagaccaatc
     2941 aagcatcgca gagagcagtt tcaagggaag aattgtcaat acctatgaaa cgactgattc
     3001 ctacaatatt ggcggtctgg tcggtcattt aacaggaaaa aatgcgtcta ttgctaaatc
     3061 caaagcgaca gtaaccattt cgtcaaacac caataggtca gatcagactg tcggtggtct
     3121 tgcaggtcta gtagaccgag atgcacagat ccaagatagc tatgctgaag gtgatatcaa
     3181 caatgtcaag cactttggta gagtcgctgg agtggcaggc aatttgtggg atcgaacttc
     3241 tggtgatgtt aggcatgctg gaagtttgac caatgttctc agcgatgtta atgtaacaaa
     3301 cggaaatgcc atcactggat accactatac aggaatgaag gtagctaata catttagtag
     3361 taaggctaat agagttttca atgtcacttt agagaagaat gaggtcgtca gcaaagaatc
     3421 cttcgaggaa agaggaacaa tgctagatgc ttctcaaatt gcaagcaaaa aagcagaaat
     3481 caatcttatc actccaccaa tagtggaacc cctctcaaca agcggtaaga aagacagtga
     3541 tttttctaag atagcccatt atcaagccaa ccgtgctttg gtttataaga acattgaaaa
     3601 attgttacct ttctataaca aggcgaccat cgtgaaatac ggaaacctgg ttaaggagaa
     3661 cagtatctta tatcaaaaag aactcttgtc tgcagttatg atgaaggatg accaagtaat
     3721 cacagatatt atttccaaca aacagactgc aaacaaactc ttgcttcact acaaggacca
     3781 ttcatctgaa aagtttgatc tcaggtacca ggctgatttt gccaatttgg cagaatatag
     3841 cattggagat agtgggcttc tctatacgcc aaatcaattc ttgtatcatc aagattctat
     3901 tattaaccaa gtgctgcctg aattgaatcg agtaaattat caatcagatg ctgttagaaa
     3961 tacacttgga atttcaccag aagtgaagct aacggagtta tatcttgaag aacaatttac
     4021 caaaacgaaa gagcatctag cagagaactt gaaaaaactt ttatcatctg atgcaggttt
     4081 agtaacagac aatgaagtta tgacaggata tataatagat aaaattaaac ggaataagga
     4141 agccttactt cttggaatga gttatttaga acgttggtat aactttagct atggtcaagt
     4201 gaatgtcaaa gacctagtta tgtatcatcc ggacttcttt ggtaaaggaa atacttcacc
     4261 attagatact ctgattgagt taggtaaatc tggctttaac aatcttcttg ctaaaaacaa
     4321 tgtcgatact tatgctatca gccttgccag ccatcatgga acgacagatt tgtttagcac
     4381 gttggaaaat taccgaaaag tctttctacc agataaaacc aataatgact ggtttaaatc
     4441 acagactaag gcttacattg tcgaagaaaa atccaatatc gaagaggtga aaacgaagca
     4501 aggactagtt ggcactaagt attctattgg tgtctatgac cgtatcacta gtgccacatg
     4561 gaaataccgt aatatggtac tacctctact taccttgcca gaaagatccg tatttgtcat
     4621 ttcaaccata tctagtctag gttttggtgc ttatgatcgc tatcgtaata aagaacatca
     4681 agcaaatggt gatcttaata gctttgttga aaagagtgct cacgaaacag cagagcgtca
     4741 acgagatcac tatgattatt ggtatcgtat tctagatgaa aaagggcgtg aaaagcttta
     4801 tcgaaatatc ttgctttatg atgcctataa atttggaact aatcatactg aaggaaaggc
     4861 tacagaagta gcagattttg atagtccaaa tcctgcaatg aaacatttct ttggacctgt
     4921 tggaaataag gttggacata atggacatgg tgcttatgct acaggggatg cagtatatta
     4981 tatggggtat cgcatgctag ataaggatgg agctattacg tatactcatg agatgacgca
     5041 taattcagat caagatattt atcttggtgg ttatggaaga agaagtggac ttggacctga
     5101 gttctttgct aaaggcttac tacaagcacc agaccaacca agtgatgcaa cgattactat
     5161 caattctata ttgaaacatt caaaatctga tagtaaagaa ggagaacgat tacaagtact
     5221 tgatccaact acgagattta aagacgcaac agatcttcaa aaatacgtcc acaatatgtt
     5281 tgatgttgtt tatatgttgg aatatctcga aggtaaatct attgttaaga aattaaatgt
     5341 atatcagaaa atagaagctc tcagaaaaat cgagaaccaa tatctaacag atcctgctga
     5401 tggaaatgat gtttatgcta ctaatgttgt gaaaaatttg actgaagatg aagctaaaaa
     5461 attgacgagc tttgatagtt tgattgacaa taacattctt tcggctcgtg agtataaggc
     5521 tggcacttat gagagaaatg gctactttac tataaaactc tttgcaccaa tcttttcagc
     5581 attgagcggt gagaaaggaa ctccaggtga ccttatggga cgaaggatag cttttgaact
     5641 tctagctgct aaaggattta aagatggtat ggtaccatat atttccaacc aatacgaaga
     5701 agatgctaaa caacaagggc aaactatcaa tctttatggt aaagaacggg gcttggtgac
     5761 cgatgagctt gttttgaaaa aggtatttga tggtaagtat aaaacttggg cagaatttaa
     5821 gacagctatg taccaagaac gggtggatca gtttggaaac ttgaagcagg tgacctttaa
     5881 agatccgaca aaaccatggc caagatatgg cacaaagact atcaataatg tggatgaatt
     5941 gcagaaacta atggatgaag ctgttttgca ggatgcaaaa gaacgtaatt attattattg
     6001 gaataactat aatccagaaa cggacagtgc cgtccataag ttgaagagag caatctttaa
     6061 agcctatctt gaccaaacaa atgattttag aagatcaatt tttgagaata aaaaatagtg
     6121 tttactatta ggaaataaaa agtgaatgtg gaggattaga attgtcatta ttaaaaaaag
     6181 ataaattttc cattcggaaa ataaagggta ttgttggttc ggtattcttg gggagtcttt
     6241 tatttgcacc gtcagttgtt ggtacatcga cttatcatta cttagattat agtactttga
     6301 cacaaactga acgtgttcaa ctcaaacaag gtagacctga tgaatcaaaa gagtcatatg
     6361 ctttggttta tgaaaaagac gcattaccaa acacaggaag ttctcaatct attatgactg
     6421 cattgggttt gttagctatc gggagtctta ttgtgattat cacaaaagat aaaaagagga
     6481 aaaaaatcgc tacatttttg attgtagggg cgacaggttt agttacacta tcaactgctt
     6541 cagcacttaa tttgaatgct aacatccatg agtctggacg tgatggtgtg ttgcaaattt
     6601 ctggttacag atatgttgat tacttggagc ttgatgatag aactgtttct ccagttgagc
     6661 aacccaaagt tgtgaccgac aaaggcgaac cagaagttca gccagcgtta ccagaagctg
     6721 ttgtaactgg aaaagggaaa actgaagtac aaccgacatt accagaagct gttgtgactg
     6781 aaaaagggga accggaagta caaccagtgt taccagaagc tgttgtggct gaaaaagggg
     6841 aaccagaagt tcatgagaag cctgactata cgcaaccaat aggtgcaaac cttgttgagc
     6901 ctgaagttca tgagaaacta gcatacactg aacctgtagg tacaacagga gtagatgaaa
     6961 atggaaactt gattgagcca cctgttaacg atattccaga gtatactgaa ccaatatcta
     7021 cagtttcaga agttgcatca gaaagagaag agttgccttc tttacatacc gatattcgta
     7081 cagagactat tcctaaaacc actatagaag aatctgatcc tagcaaattt ataggcgata
     7141 attctgttaa acaagttggt gaggatggcg aacgtcaaat tgttactagc tatgaagagt
     7201 tacatggcaa aaaaatcagc gagtcagttg aaacagtaac aattttgaaa gaaatgaagc
     7261 ctgaaattat tgtaaaaggt acaaaagaaa gaccaaaaga aaaaacggct cctgttttaa
     7321 ccttgaccaa agtaacagaa gatgctatga atcgttctgc caacttaaat tatgagcttg
     7381 ataataaaga taatgctgaa atatcaagta ttgtagctga aattaaagat ggtgatacag
     7441 tagttaaaag ggttgattta tctaaagaaa aattaactga cgctgtacaa aatttggatt
     7501 tgtttaaaga ttataagatt gcaacaacaa tgatttatga tcgtggtcaa ggttctgaaa
     7561 cgtctaaact ggatgaaaga cctctgcgtt tggagttgaa aaaggtcgaa attaaaaata
     7621 tcgcatctac taatttagtg aaggtaaatg atgatggtac tgaaacacct agtgatttta
     7681 tgaatgaaaa accttcagaa gaagatgtta aaaaaatgta cttaaaaatc actagtcgcg
     7741 ataataaggt aactcgttta actgtagact ctattgaaga agtgactgaa gaaggtcaaa
     7801 aactttacaa aataactgct gaagcacaag atttgattca acacacagac ccaacgaagg
     7861 ttcgtaataa gtatgtttat tatatagaaa aaccccatcc taaagaagat aatgtctact
     7921 ataactttaa agatttagta gatgctatga atactgataa aaatggtaca tttaaacttg
     7981 gtgcagattt gaatgccact ggtgttccaa cacctaagaa atggtatgtt gacggcgact
     8041 ttagaggtac attgaagagt gtagagggga aacattatac tatccacaac acggagcgtc
     8101 cgttattcca gaatattatt ggtggtacag taaccaaagt aaatctggga aatgtaaata
     8161 tcaatatgcc atgggcagac cgcatcgcac cgattgctga cactattaaa ggtggcgcta
     8221 aaattgaaga tgtcaaagtg actggtaacg tattaggtag aaactgggta tctggattta
     8281 ttgataagat tgacaaccaa ggtacactca gaaatgtagc ctttatcgga aatgtgacat
     8341 ctgtaggtga tggtggtcaa ttcttgaccg gtatcgttgg tgagaactgg aaaggactag
     8401 tcgaacgtgc gtatgttgac gcaaatctta ttggcaagaa agccaaggct gctggtattg
     8461 cttattggac acaaaacagt ggtgacaatc ataaagttgg tgtcgaaggt gcagtcaaga
     8521 aaggaattgt gaagggtacc attcaggtag aaagtcctgt tgaagtcggc ggtgctgttg
     8581 gacgtttgag tcatcatggt tatatcgggg aagtcgtatc tatgatgaaa gttaagaagg
     8641 gtgaaatttt ttatggttct agtgatatga atgatgaccc atattgggtg gcgaataatg
     8701 tacgaggaaa ttatgtagtt aatggtgtga gtgaaggtac gatatcttat gctcgtgcta
     8761 aagaacacca tcgtatcaaa ccaatttcac agtcagaagc agatactaaa attatgatgt
     8821 taggtattac agcacaagat tttgctatca acgaacctgt ggtcaatcgc ttaaaccgtt
     8881 taaccagaaa agaagatgaa tataagtcaa cccaagacta taaagtagat cgagatctgg
     8941 cttatcgtaa tattgagaaa cttcaaccat tttataacaa agaatggatt gtcaaccaag
     9001 gtaacaaact tgcagaagat tcaaacttag ctaagaaaga agtcctttct gttacgggta
     9061 tgaaggatgg acagtttgta actgacttat cagatattga taagattatg gttcactatg
     9121 ctgatggtac taaagaagaa atggacgtca ctaagaatgc tgattctaaa gtgaaacaag
     9181 ttcgtgaata taccatcgct ggacaaaacg ttgtttatac accaaatatg gttgagaaag
     9241 accgtaacca attgattcaa gatatcaaag ataagttggc gtcagttcaa ttgatttctc
     9301 ctgaagtacg tgctttgatg gatgcacgta agaaaccaga agaaaatact gatgaacgta
     9361 agaatggtta tattaaagac ctttacttag aagaaagctt tgctgaaacg aaagctaatc
     9421 ttgataaatt ggttaaatcc ttagttgaaa atgcagatca tcaattaaat agtgacgaag
     9481 cggctatgaa agcacttgtt aagaaggtgg atgaaaataa agctaaaatc atgatggctc
     9541 tgacttatct caatcgttac tatgatatca agtatgggga tatgactatc aagaacttga
     9601 tgatgtttaa acctgatttc tatggtaaat cagttgacct tcttgatttc ttgattcgaa
     9661 ttggatcaag tgagagaaat atcaaaggtg acagaacttt ggatgcttat cgtgatatga
     9721 ttggtggaac tattggtaag tctgaattac atggattctt agattacaat atgcgtctct
     9781 tcactaacga tactgattta aatgattggt tcatccatgc agctaagaat gtatatgtat
     9841 cagaacctca aacaacgaac ccagattttg ttaataaacg acatcgtgca tttgatggtt
     9901 tgaacaacgg tgttcataat cgtatgattc tacctctatt aactcttaag aatgcacata
     9961 tgttcttgat ttcaacttac aatacaatgg cttatagttc ttttgagaaa tatggtaagt
    10021 atacagaaga agctagaaat gaattcaaaa aagaaattga taaggttgca catgctcaac
    10081 aaacatactt agacttctgg tcacgtttag cattgccaag cgtacgtgac caattactca
    10141 agagtgagaa tagggtacca actcctgtgt gggataacca aaactatagt ggtattaaag
    10201 gaataaaccg tatgggttat gatgagaaga aagtaccaat tgcgccaatt cgtgagttat
    10261 atggtccaac ttggaaattc cataatacca actggaatat gggagctatg gcatctattt
    10321 tcccaaatcc taataacaat gaccaagttt atttcatggg aacaaatatg attagtccgt
    10381 ttggtatttc agcctttact catgaaacta cacacgttaa tgatagaatg ctttacttcg
    10441 gtggtcatag acaccgtcaa ggtacagacg tcgaagccta tgctcaaggt atgctacaaa
    10501 ctccgtcaag tattggtcac caaggtgaat atggtgcttt aggtttgaac atggcttatc
    10561 atcgtgaaaa tgatggtgac caatggtata actatgaccc tgataagctt caaactcgtg
    10621 aagatatcga tcgatatatg aaaaactata atgaagcact gatgatgcta gatcatgtag
    10681 aagcagacgc cgtacttcca caattgaatg gtgataatag caagtggttc aagaaaattg
    10741 atagagaaat gcgcagaaat cttggggatg gtttgaataa cttagtagca ccgcaccaat
    10801 gggacaacgt tcgtgactta aatcaagaag agagttctaa gaaattatca agtattaacg
    10861 atttgattga taataatttc atgaccaaac acggaaatcc aggtaacgga cgttatagac
    10921 cagaggattt tagaccaaac tcagcttacg taaatgtcaa tatgatggca ggaatttacg
    10981 gtgggaatac gagtcaaggt gctcctggtt cattatcgtt caaacataat gccttccgta
    11041 tgtggggtta ttatggatat gacaaaggtt tcactagtta tgtatctagc aaatatcaag
    11101 gtgaagctga taaacaaaac cagggtagat taggtgatga tttcattatc aaaaaagttt
    11161 caaacaacca attctcaaat cttgaagatt ggaagaaata ttggtatcat gatgtgaaat
    11221 ccagagctga aaaaggattc acagagatta caattgatgg acaaaccatt cacaactata
    11281 atgaactgaa agacttattc gacaaagctg tcacagaaga cctcaagaaa gctggaaact
    11341 actcaaatac tgagaatttg aaatccaaag tcttcaaagc tcttcttaaa aacacagacg
    11401 gtttctttaa tccattgttc aaaaaagaca tttaaacccc aattatgcac cccaaatcta
    11461 aaaaccatcc agaatccttg ccttagctta gatcctggat ggtttctttt t
//
LOCUS       DAVIME010000060        10708 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVIME010000060 DAVIME010000000
VERSION     DAVIME010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.060"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(63..1487)
                     /locus_tag="VV588_001880"
     CDS             complement(63..1487)
                     /locus_tag="VV588_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU7084168.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVTWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2032..4311)
                     /gene="pulA"
                     /locus_tag="VV588_001881"
     CDS             complement(2032..4311)
                     /gene="pulA"
                     /locus_tag="VV588_001881"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU7084169.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4423..6381)
                     /gene="ligA"
                     /locus_tag="VV588_001882"
     CDS             complement(4423..6381)
                     /gene="ligA"
                     /locus_tag="VV588_001882"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU7084170.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEVKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6474..7652)
                     /locus_tag="VV588_001883"
     CDS             complement(6474..7652)
                     /locus_tag="VV588_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU7084171.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7732..8595)
                     /locus_tag="VV588_001884"
     CDS             complement(7732..8595)
                     /locus_tag="VV588_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU7084172.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISSHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8598..10499)
                     /locus_tag="VV588_001885"
     CDS             complement(8598..10499)
                     /locus_tag="VV588_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU7084173.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKFSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3211 a         2364 c         1910 g         3223 t
ORIGIN      
        1 taattattat tattttatag caaaaaaata aaaccaggaa aacaatttcc tgattttaca
       61 cgttatttca catcaaaaac aatggatttg acatttgtca tcgcttcaat gctatattta
      121 attccttgca ctccagctcc agaacctttg acaccaagga atgggaaatt atctggacca
      181 cgctgggttt tattattaat gtggactgta cctacttcaa gtttttcagc aatttcaaag
      241 gcttttttga aatcatttgt aaagactgat gattgaaggc cgaattcaga ttcgttggca
      301 aaggcaatag cttcctctac actagccaca cgaatgattg gtaaaacagg accaaatggc
      361 tcttcccatg tcactttcat atcttttgta acttggtcaa aaagcactgg ccagaggaga
      421 ttgccctcac gtttgattgg tgtaagagcc tgagcctctt tttcttgtgc atcctcaatc
      481 aagccccaaa tgaagtcggc tgaagcattg tcaataacag gtgtaatatc agcattgtca
      541 aatggatcac caactgttaa tttagaaact tcttcctgaa gcaaagtagc taatttatct
      601 gctacacttt cgagaacaat gacacgttta atggccgtgc aacgttgtcc tgagtagcta
      661 aaggctcccg caacaatttg cttggcagca tgttccaaat ctgcatcttc tagtacaaga
      721 gctgcatctt tcccaccaag ttccaacatg ataggacgca taccagctaa acgaccaata
      781 cgttctccaa taggagttga acctgtaaag ttgatgaagt tgacttcttt gtgctcaatg
      841 atataatccc caatttctga accacgacct gtaatggtgt tgaaaacacc tgccggaatc
      901 cctgcttctt caaatgcttt agccaacaag agtccagaaa tggaaccttg tgttggtggc
      961 ttcaacatga ccacattccc tgcaatcaag gcaggtgcaa ttttagaagc agataaatta
     1021 actggataat taaagggagc aatcgctagc acgataccaa ctggttcacg acggacaaca
     1081 gccagtttgt ttttacttgc tgcctcaaaa ccaccacctt ccattgcttg tccagtgata
     1141 cggagacctt cctcagcagc ataacgaatc aagtctgctg tacgcactac ttctccaatt
     1201 gctgctttaa tcccttttgc tacttctttg gcaaggatag taccaatttt ttccttatcg
     1261 cgttctaaaa tagctgctgt tttatgcaaa taagccgcac gttcaattgc tgataaagct
     1321 cgccatgctg gcagggctgc acgcgcagct tgcatagcct catcagcttc agtctgagtc
     1381 atggctggaa ctgtacccaa ttcttcttga ttgattggtg aataaatcgt aatttcttgt
     1441 tcagatgatt tccattttcc atttactaaa ttctgatatc ttgtcaaatt cttgtcctcc
     1501 tgaaaatgat taagatatat tttaccaaat tttcagaaaa tcacaaccct ttttgcaaaa
     1561 tttttgagat tattttcaca atcttgattt ttcaaagtat actcaataaa aattaaaaaa
     1621 atccactacg tcaaggcgag gctaatgtgg tttgaagaaa ttttcgaaga gcgtgaatga
     1681 gtatcatcta tagtaaaata aaaaaactga acaatttggt tggggacagc caaaccaatt
     1741 tctcacaatg tttcagaaac aagggtgtgc tattccaatt tcagcctact ataactgtca
     1801 tagattgctg aaacaaagtc taggtaaaag tcttcataat aaaaagacct cctatcaagt
     1861 gttcaaaaac tttgatagga ggtcttgttt tgtgaaaata tttatcaaat tttctataca
     1921 agtgagctgt tagccaggtt ctttctattc tttcaatttc aatgaatgga ttttttacta
     1981 atactcataa ctgggaattt gtctgtgtaa aaatagcgag atagatggta tttataaaac
     2041 actcaagaca gctagactaa tatcatttaa aacattatct tcttttgagc gactgttggt
     2101 taccaacata gctaaatttc ctgcattttc aaattgatag ggttctgatt tagcattcac
     2161 aactaccaag aggtgttctt tgccgtgaac ttcatagata aggcagccgc tatgttcaat
     2221 cgcagaatgc acaaagacat gatggtaaat ttcatcatag ctagagtaag aaaaggcacc
     2281 agtttttgtc ttcaatcgga tgacttgacg gataaactca atactgtctt gacgctcatt
     2341 aatcaagttc cagttcactt ggttcacact gtcaggagca ttatagctat tcatcgcacg
     2401 ctctctatca tcatgggtca actcaccatt ttcaccagtc gcaaccagtt tggtacgacc
     2461 aaattcttga ccgatttcca taaaggccat cccctgcatg agcagattca tggctgtggc
     2521 agtttcgacc ttgcgcatga tttgctctga actttggtct ggatgaaggg ttgccaataa
     2581 atcgtgaaga ttgtaattgt catgggcttc tacatagtta agcacctgat ttggatgtgt
     2641 atagcttcct aattcacgac ttcctaggat tgctttagct agaattggct ctgtcgcagc
     2701 accactgaca aaacctgact tgatagcacc ataaacttct ccccctttga cagcatcgcg
     2761 ctgattgtca ttaaagaaac caatatttgg catctggtag gcattgtcct tcttggcctt
     2821 atcataaggg gcaagacctg ttcccatatc ccatccttct ccatagagga taatgttgga
     2881 gtcgatttca tccaagcttt gacgaatcat ctgcatggtc ttgacatcat gaatccccat
     2941 caagtcaaaa cggaagccgt caatattata ttcctgcacc cagtatagaa gagaatcaat
     3001 catatacttg cgaaacattt cgtgttcact ggctgtttca tttccaacac ccgttccatt
     3061 ctggaaggta ccatctggat tcatacgata atagtaatca gggactgttg tttggaatgg
     3121 tgcatcaaca actgagaagg tatggttata gactacatcc ataatgactc caatacccgc
     3181 atcgtgataa gcttgaacca tcaccttcaa atcacgaatg acctgagctg gatcatctgg
     3241 attagttgaa aaactagttt ctggcgcgtt atagttttgt ggatcataac cccagttgta
     3301 ggttacattt ccatcctcat cgtattcttt atgacggtct gcaattggtt gcaattgaac
     3361 ataattgtag cccagcttct tgatgtaatc aaaagcagtt gactggccgt attggttaac
     3421 tgttccagcc tgagcagcac ccaagaaagt tcctcgaaga tgttcatcta cacccgatgt
     3481 aggtgattta gtcaaatcac gaatgtgcat ttcacagata actgccttac atggattttc
     3541 caagcgccaa gtagcctccg aaccgtgctt aacctcgaag ttttcaactt gcttttctac
     3601 atggctcaga atagctgaac gtttgccatc agggctggtc gcgattgtat aaggatcacg
     3661 tgtcagtgtt tggtgatgag ggaattggac ttgatactga taagtcttac ctaccaaatc
     3721 ttcttcaaca tccaaactcc agacaccgat tgtattgtcc ttatgattat aagagtagct
     3781 attgcctctt ttcatctcaa aagtcttcca aacgggtgca tcattagcag ctgattcata
     3841 aacgacaact tgcacttctg tcgctgtagg tgaccagaga gaaaaatgag cctgattgtc
     3901 ctctacacgg caacccaatt ctccttggta accccaatga tgatcaaaac tagcactgtt
     3961 aatggcctta tcaaaggcaa aaggattttg atttttatag aaaggactgg caatagcagg
     4021 attttcagag taataaatcc tatcatcgcc ttccaaaatc cagacctctg ttaatagggg
     4081 atagtgatta aaacggatag aatattcttt actagtttga cctgtatgaa ccacaaaatt
     4141 caagctttct ataacatgtg aacttgggtg ttcaaagcta aataaagctc caaaataatc
     4201 ttctttgtag gttagcaaat caattcgttg atcctgactt tttacaaagg agcaagtgtc
     4261 atattctcca ttcttacgat ggtaatgaat gcgcataggg tagttataca ttttttattt
     4321 ttccttttta ctttgtttct atttcactaa taaatttttg tcaatctcgt ctcaattaac
     4381 agacatagtc atattctcta aactctgttt ttaaacgatc cattacaaac tttctagcca
     4441 tgcctcatct ctgacctgga taccaagttc ttgtgctttt tgcagtttac ttccagcgtc
     4501 tgcacctacc acgacgaggt cggtcttttt agaaatacta cctgtcactt tggcacccag
     4561 actttcgagt ttacttttaa cttctgagcg cttgagtcgt tccaattttc ctgtcaatac
     4621 cacggtcaaa cctgacaagg ccgcatccgc tactaccgtc tgtcctttat agtccagatt
     4681 gaccccagtt tctttcaatt ctctgagcag aatttcagag ccttctgtcg caaaataagt
     4741 ctgaagactt ttggcaatca cgccacctag actttcaata ctagccactt cctctgaatc
     4801 tgcctgagac agattttcaa ttgaatggaa atattgaagt aaaagctgac taaccttgct
     4861 tccgacatga cgaattccca aaccaaataa gagcttctcg gcagagtttt cctttgatgc
     4921 ttggatagcc tgatacagtt tagcagcgga cttttcctta accccctcta aaaggaggaa
     4981 atcctcttct tgcaaacgat aaatatccgc cacatccttg actaaattag cagcaaaaag
     5041 cttctcaaca atagatggac caaggcctgt aatattcata gcatcacgag aagcaaagtg
     5101 aatcaagcct tccatgattt gagcagggca acgcggattg atacaacgta gggccacttc
     5161 atcttcaaag tgcaacaagt cagagttaca acttggacag tttgtaggga tatctagttt
     5221 ttcttcagaa acccgtttgg actctaccac acgtaaaacg gcagggatga tgtcaccagc
     5281 cttatataca atgaccgtat cgtcttttcg gatatctttt tcagcaatat aatctacatt
     5341 gtgcagggtc gcacggctaa cagtcgtacc ggcaagttgt actggtgtta gattagcagt
     5401 tggagttaca acaccggtac ggccaactgt ccagtcaact gataagagtt gagcttcttt
     5461 ttcttcggca gggaacttgt aggctactgc ccactttgga gccttaacgg taaaaccaag
     5521 ttcttcttga cttgctaggt cgttgacctt gattaccact ccatcaatat cgtaaggcag
     5581 attttcccgt tcctgtccta cttcttggat aaaattccag atttcatcta tgttttcagc
     5641 caagattcgc ttaggattga ccacaaaacc tagttgttct aggtacttca aacccttttc
     5701 ttggctatca cgagttgaag ggctggcttc ttgatagaga aacgttgcaa gattacgctt
     5761 ggcaactact gctgtatcca actgacgcag agttcctgct gccgcattac gaggattagc
     5821 aaattcaggc tctccatttt cttggcgcac ttggttaact tggtcaaagg aagcgcgtgg
     5881 catgtaacat tccccacgaa ctgtgatatc tagttcttct ggcaaagtca aagggatgtc
     5941 cttaacacgc ttgaggtttt ctgtgatatt ttcaccaatt gaaccatctc cacgtgttac
     6001 cccagcaacc aaaatcccct tttcataagt cagcgagata gataagccat cgattttcag
     6061 ctcacaaata taggtcggat gagccacttc cttacgaaca cgcgcatcaa aagcatctag
     6121 ctcctcacgt gaaaaagcat cctgcaaact ataaagagga tactgatgac tgtatttttc
     6181 aaaaccatct aaaaccttgc caccaacacg atgagtcgga ctgtctgcta gcacttgctc
     6241 tggataagca gtttctaact cgaccaactc acggtaaagg cggtcatact cactgtctga
     6301 aaccgaggga ttatcgctgg tatagtactc agtcgcatag cgattgagca aagcgactaa
     6361 ctcattcatt cttttattca taagaccatt ttaccataaa acaagccctc ctcacaaacg
     6421 agaagggcgg aaaaaacact tagtttgaaa ttatttttga aactcaagca accttatatc
     6481 aatttttcaa aatgagttcg aacataaata aacgatatac aagacaagat gataacacca
     6541 cttccaatta tcaggaaaga agagagatgt acacttggca agactgtcat aaatcctttt
     6601 gcaataggca taaatagaat agctaaggta aaaattgtac tcagtactct tccaagaaat
     6661 tcgctctcaa ccttggtttg tacttgagta aaaaagtgaa tattaaaaat cgtcataaac
     6721 aattcacaaa ctaaatttcc agaaaaggaa agaaaagttg gaagtggtaa tcccatcata
     6781 aaaactccga cacctgtcaa agccagtaaa atcaaaagat tataaatatt agctttaatt
     6841 ttactagcta gaagagcccc aatgatggaa ccaatagccc ccatagttaa aatacttgca
     6901 taggctcctt ctgacccgta aagctgattc gaaaagggaa gtagaaattc aaaagctgca
     6961 aaaaagaaat taacgctgga agctaccagc aaaaggaaga aaatttcttg ctgatgccag
     7021 atatagtgta acccatcctt gatatctaca aaaatatctc tcccagtaaa agcctttttc
     7081 tcttgaactt ttgcttcctc ttttggaagg aaagccacta gaacaaaagc aatgaaaaaa
     7141 gtcagcgagt ctagcagtag cgtcatatgg agacttgcaa actgtaaaac aaggaaggaa
     7201 agaacaggag agctaacacc tacaacctgc aaaaccagct ctaggcgaga attatagatc
     7261 acaatctcat ctttctccac cacttcagtt atgatagctt tattggctgt gcgagaaaag
     7321 gcaaaagcaa tagcctgcac aatgttagca acaatcaaag cgccaatcat ccagctatca
     7381 ttccttatga aagaaatagc cagacaaaga atcccacaaa caagatctgc cgtcattaaa
     7441 atcttacgac gagaaaaacg gtctgaaata actccgccaa agggattgac gagaatagat
     7501 gtgacgagct cagaaatctg atacattcct aaaactgtct gtcctatagt ccccatagaa
     7561 gccaaccaga cactatttcc ataatcatag agcatatttc ccattttatt gatagcccca
     7621 cggctaatca actgcactgc atagcgattc atattaaagc tcctctcaaa ttttgaaact
     7681 attgtatcaa aaccgaaagg agctttttat tttttccctt atttgggaaa attaactttt
     7741 gacaaatttt tcgtagtgtt cctgataata ggctacttgc tctggaagac ctaacacatc
     7801 aaaaatatgt atggcctctt gcatctgctt acagccttct ttacactgtc ctttttgata
     7861 taaggcaaaa ccttttaaat aatggaaaac attacgctca taaagcttaa tacctttgtc
     7921 aataatcttc tctgtataag cctcaaaata gttggcatta taaaaagaag aatgctctaa
     7981 acaatgctgg taacaattga gggccaaaat caacactaat ctcttatggc tactaatctc
     8041 ttggtaaaat tcctccctct ccataacttc tctaccaatc cgagtgacat aatccacatc
     8101 gtagaaacta tagaggttac cgaaaagaat caactcatac atggtccatt cttctgtttt
     8161 gaagagataa tctgctacct tatccaaatc atcctgcttc atatcataac tcgcatctct
     8221 ttgacaaatc agaccctgta gcaaaatcca gttcagctca aaataaaggg gagtcgtcga
     8281 actcttagac ttttcaagtt gttctctttg aagcttttga aaacctgcaa tatcgtttga
     8341 atagtaaagt gggataatct gtgccatcat agacacatgt tcatgattat gaaaattcct
     8401 tgccttatcc atgaaatttt cgattgttac atgaatgtta tccaaaatct caaagaaacg
     8461 ggagactgcc aggtcagact ccccaagctc aaagcgagat aactgagagg tagagcagga
     8521 ttcgcctgct gcttccttca aagaataatt tccacttgtt cgaaattcac gaaatacttt
     8581 tccaagatgt tccatcttta cacctgctct gataattctt cccactcaag catagcttct
     8641 tcctgacgat ggctgatttt gtccagctca gcctgtaatt ccatgagttt gtcggcatcg
     8701 tttgtttcca acatttgttc agaaatggct tggctttgac tttctagctc ttcaatttca
     8761 gcttctagac tttcgatttg tcgcatgagt ttgcgaactt ctttttgact ttctttctgg
     8821 gcctgatagt cattgactgg acttgcttcc tttgcttgat tgctagttga agcttcctca
     8881 gtctgactca tttctgctgt tgctttcttc tcaacatagt agtcgtaatc tccaaggtag
     8941 agagttgaac cattctcaga caattccaaa acatgagttg ccacacgatt gataaagtaa
     9001 cgatcatgac tgacaaaaag caaggtacca tcaaagtcaa tcaaggcatt ttctagcact
     9061 tccttactat caatatccaa gtgattggtc ggctcatcca gaatcaaaaa gttattgttt
     9121 tccatagaaa atttagctaa aagcaaacga gctttttcgc caccagatag catgccgact
     9181 gattttttaa catcatctcc tgagaaaagg aaggctccaa gacggttgcg gatttcaact
     9241 tctggtgtca gtttgaaatc attccagagt tcatccagca ccgtattact tggtgtcagc
     9301 ttgctttggg tttggtcata gtaaccaacc tcaacattag cgccaaagcg cttttctccc
     9361 ttgataaaag gaatctggtc cacaatagac ttgataaagg ttgacttgcc gataccattt
     9421 ggaccaacga tagcgacagc attcatctta cgaagatcta ggttgatagg ttgtgacaag
     9481 acttccccgt catagccaac agctgcattt tcaacagtca aaacaacatt gcccgacgtt
     9541 ttttcagact ggaaggtcat gttggctgct ttcttgccag cttcaggctt gtccaaacgc
     9601 tccatttttt ctagttgttt acggcgagat tgagcacgtt tagtcgttga agcacgaact
     9661 agattgcgat tgacaaagtc ttccagagca gcgatttcct tctgttgctt ttcatagttt
     9721 tttgcctcag taactagctt ttgctccttc aattcgacaa aacgagagta attccccaca
     9781 tagcgatcca aggaatgctt ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa
     9841 taacggtcgt ggctgacgat aatgagggca ccgctatagt ttaccaagta attctctagc
     9901 caggcgatgg tttcaatatc caagtggtta gttggctcgt ccaagaccaa gagattgggc
     9961 ttttcaagga gcattttggc aagtgccaaa cgagtatttt gaccaccaga aagctcagca
    10021 attttcatct gccacataga ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatatca
    10081 gcttcatagg taaagccacc tgcttggcga aaattctcag ataagcggtc ataatctgac
    10141 atcagtttat ccaaatcctc accagacttt tcacccatct ccagctccat ctgacgcagt
    10201 tgtctctccg tccgacgcaa atcattaaag acatgaagca tttcatcgta gatggtattt
    10261 tcagactcaa aacggctatc ttgggctagg taagacagag aaatatcttt tttcttattg
    10321 atttctccgc tagttggctc ctcttctcca actaaaatct tcaaaagagt agacttacct
    10381 gcaccatttt tcccaacaag agcaatccga tctcgttcat caacctgcag gttgatatta
    10441 tcgaaaagaa cctctcctgc aaaagaacgt tcaattttat tagcttgtaa aataatcata
    10501 agagtagtat agcatgtttc cctaaggcat tcaagataat cgtaagtctt ttagtacaac
    10561 ttttataaca taaaataaac taaattatgt atattttata ttagattctt cactatcttg
    10621 ttggattttc taaccagcta atcttgtttc aaatagttat cgcacaagcc tattatttaa
    10681 ttcttttcat tatttacgta cgtatagc
//
LOCUS       DAVIME010000061        10530 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVIME010000061 DAVIME010000000
VERSION     DAVIME010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.061"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(34..270)
                     /locus_tag="VV588_001886"
     CDS             complement(34..270)
                     /locus_tag="VV588_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU7084174.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(338..1258)
                     /locus_tag="VV588_001887"
     CDS             complement(338..1258)
                     /locus_tag="VV588_001887"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU7084175.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDSDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1448..1851
                     /locus_tag="VV588_001888"
                     /pseudo
     CDS             1448..1851
                     /locus_tag="VV588_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2067..2648
                     /locus_tag="VV588_001889"
     CDS             2067..2648
                     /locus_tag="VV588_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU7084176.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            2645..3922
                     /locus_tag="VV588_001890"
     CDS             2645..3922
                     /locus_tag="VV588_001890"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU7084177.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3940..4602
                     /gene="deoC"
                     /locus_tag="VV588_001891"
     CDS             3940..4602
                     /gene="deoC"
                     /locus_tag="VV588_001891"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU7084178.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASADKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4589..4978
                     /locus_tag="VV588_001892"
     CDS             4589..4978
                     /locus_tag="VV588_001892"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU7084179.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5069..6121
                     /locus_tag="VV588_001893"
     CDS             5069..6121
                     /locus_tag="VV588_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU7084180.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6265..7800
                     /locus_tag="VV588_001894"
     CDS             6265..7800
                     /locus_tag="VV588_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084181.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENITLQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7793..8851
                     /locus_tag="VV588_001895"
     CDS             7793..8851
                     /locus_tag="VV588_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7084182.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8854..9810
                     /locus_tag="VV588_001896"
     CDS             8854..9810
                     /locus_tag="VV588_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7084183.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            9894..10530
                     /locus_tag="VV588_001897"
                     /pseudo
     CDS             9894..10530
                     /locus_tag="VV588_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3073 a         1845 c         2414 g         3198 t
ORIGIN      
        1 acttcaaccc actacagttg acaaagagcc ttcttattta gcaagtttag ctgaaagacg
       61 agctttatcg cggcttgctt tgtttttgtg aatcaaacct ttagtttctg ctttatcgat
      121 agctgagcta gcagcacgga aaagttcttc agatgggttt gcttcgaaag cttttatagc
      181 agtacgcata gctgattttt gagctgagtt cttttcgttt tgtttaacgt tcaattcagc
      241 gcgtttgata gctgatttaa tgtttgccaa tgttcttacc tccatattta ctaactatac
      301 cattatatat gaaaacttac gttttgacaa gggaaaatta tttttttaag taaatttcat
      361 cgatttcatg gttcttgctt ttatgaagaa tcacttctgc acgatttctg gttggttcaa
      421 tataattttg tagatttgtg agattgatac tggtccagac ctgatgggca aaggcttcca
      481 cttccccaat cggcatctga gtaaaacgat aatagtagct atcagagtcg ttttgggcta
      541 gactcagcat tttcaagaaa cggtccagat accaactttc aatatcatcc actccagcat
      601 ctacatagat ggaaaagtca aagaagtcag tgatatagag acgatcgttt tgtggatttt
      661 gaaagacatt gattccctca acaattacaa aatcagcagc tttgacactt tgtttctctt
      721 cgggtacgat gtcgtaaact tcatgagaat agacaggaat atctacatct tgtccatttt
      781 tgatgcggtc caagaagttg agaagagctt ccatatcata gctttcagga aatcctttac
      841 gatttaaaat cccctgctca atcaaggttt gattgggata gagaaaacca tcagttgtaa
      901 ccaactcaac cgtagcatct gtaaacgtac gggacagtag gatttgaagt aggcgactgg
      961 ttgtggattt tccaacggca acactcccag aaaccccaat aataaaaggt tgagatttac
     1021 tttcacgttg gaggaaaatt ccttttgaaa aggctaaatc ttccttagtt cgcttgtaaa
     1081 tctgaatcag atgagccaag gggagataga tatctgtaac gtcttggaga ctgatttggt
     1141 cattaaaact cttgatagat tccaattctt cttctgtcaa aggaggtgtt gtctttcgat
     1201 gtaaagattg ccaagtctgg cggctgattt tttcaaaatg taaaaattcg ttggtcattt
     1261 gttttcccct agatattttg tctatcatac cataaaaagc taaaaaaata aagcggtttc
     1321 ttgaatgtgg taagtcaatg gtatatagta taagtgatca atttattgat gaaataggag
     1381 atagattcta ctgatttata agcttataaa gggggctttt tagttcacaa cttataggag
     1441 gtgtactatg aaaatcttaa aacgttacat attggaactc tgttttattt taagttttgc
     1501 tttacctttt ataaaaggag ccaatgcaga taatggtaga tgctttgtgg aaacctatta
     1561 cggttttact tttttgatgg aacatgctat tgtaacagct gtctttatct gttcgttctt
     1621 aattgctttc ttactaaaaa acgatgggcg aaatggattg ctgcgggtag ttattgcttt
     1681 ttagtcctac ggattgcgac agagggttat ttcttccaca tgtcactaga agatttgata
     1741 cgactttgga caagtttgga aatcctgaca caaacgtatc agttgggctt ttatctaaac
     1801 attttgttag gaattttgtt gataataaag tattttaagg ttaagcaata gaaataataa
     1861 tctgcctgat tatagatgat aaactttttg tttttatctg gactgtgata tttatagttc
     1921 taaatggttt attatttata agtgttgaaa gagattgaag aaaatggctt cgtgacttgc
     1981 tttcttcggt ctttttcgtt ttattatcaa tttgtaaacg atttacaatt tgagtcaaat
     2041 tatggtaaaa tagtgtcatg agtaaaatgt actatgcaga aaatcctgac gctgctcacg
     2101 acattcatga gttgagagtg gacttgttgg gagaaaaaat gacttttttg acagatgcgg
     2161 gtgtttttag caagaaaatg gttgactttg gaagtcaact cttgctcaag tgtctggatg
     2221 tcaaccaagg agagacagtc ctagatgtag gctgtggcta tggtccatta ggtttgtcct
     2281 tggtcaaggt ttacggagtt caggcgacca tggttgatat taacactcgt gccctggatt
     2341 tagctcagag aaatgctgaa aaaaataatg caaaagcgac gatatttcaa tctaatattt
     2401 atgcaagagt tcaagggcga tttgaccatg tcatttccaa tcctcctatc cgtgcgggca
     2461 agcaagtcgt tcatgaaatc atcgagaaaa gtaaagattt cttggaaatt ggtggagatt
     2521 tgaccatcgt catccagaaa aaacaaggag ctccaagtgc caagtctaag atggaagatg
     2581 tgtttggcaa ttgtgaaatc cttaaaaaag acaagggata ctatatcctt agaagtgtga
     2641 aagaatgaga gcagttgatt taatccaaaa aaaacgagac ggtcaagaac tgacttcaag
     2701 tgaaattgaa tggctgatag aaggctatgt atcaggaact gttcctgatt atcagatgtc
     2761 tgcctttgct atggctgttt attttaaagg aatgacgact cgagaaatct ctgatttaac
     2821 gatgaatatg gttaagactg ggcaagagtt tgacctgtca gccattgatg gtgtgaaagt
     2881 tgacaagcat tctactggtg gtgtcggcga taaggtaacc ttgattttag ctcctcttgt
     2941 tgctagcttc ggtgtgcctg tagcaaaaat gagtggtcgt ggtcttggcc atacaggcgg
     3001 aacaattgat aaattggagt ccattaaggg ctatcaagta gaacgtagtc aagaggattt
     3061 tattcgtcag gttcaggata ttggagtatc tgtcattggg caatcagacc agctggtcaa
     3121 agcagataag cttctctatg cccttcgtga tgtgaccgca actgtcgaca cgattccttt
     3181 gattgcgagt tcggtgatga gcaagaaaat tgcggcaggg gcggatgcta ttttgctaga
     3241 cgtgactgtc ggtgagggtg ccttcatgaa gacggttgat gaggcgcgtg agttggctca
     3301 aactatggta gatcttggta aggttgttgg acggaagaca gtagcagtga ttacggatat
     3361 gagccagcct ttgggacgag cgattggaaa tcgtctggaa atccttgaag cattggagat
     3421 tttgcaaggt caaggacgtc aggatattac ccactttatt tgtgaattgg ctcaaattat
     3481 gcttggtttg gcaaatgtta acaagactgt tgaagaagtt cgccaacatc ttgagaatgg
     3541 tcaagcactg gctaagtttg aggaaatggt gcaagcccaa ggtggagact tggaagacct
     3601 ctatcgtcct gtaaatgtag ctcatgtggt ggaaatccct gctcaggaaa cgggtgtcat
     3661 ttcagctctt ccagctatgg actttggtct ttatgccatg aggctgggtg ctggtcgtgc
     3721 agttaagtct gatgccttgg actatgaaac aggaattgtt tttgaaaaga agattggaga
     3781 ctccgttcaa aagggtgaaa ttgttgcaaa agtatacaca aatgaaaaaa ttccacctca
     3841 actagttaca gatttccaaa aatgtgttaa aataagtgat gaagtgaaaa aaatccgtga
     3901 aattgtagaa atcatctcct aaatggaggg aaaaccgaaa tgaaattaaa taaatatata
     3961 gatcatacgc ttttaaaaca agatgcaaag aaaaaacaaa ttgatagttt gttgtctgag
     4021 gctagagagt atgactttgc cagtgtttgc gttaatccga cctgggttga acatgctaaa
     4081 aaaggacttg aaggcacaga tgttaaggtt tgcacagtag taggtttccc tttgggagca
     4141 acaacttcag ccgtgaaagc atttgagaca aaagaagcta tccaaaatgg tgcagatgag
     4201 attgatatgg tgatcaatgt tggagctctc aaatcaggta atttagcctt ggttgagtca
     4261 gatattcgcg cagtagtgga agcaagtgct gataagttag tgaaagtcat tattgaagct
     4321 tgccttctga cagaccaaga aaaaattgtt gtttgccaat tggcccaaaa agctggggct
     4381 gactttgtta aaacatctac tggtttttca actggtggtg ctacgatagc agatgttaca
     4441 ttaatgcgtg aaacagttgg atctgatatg ggagtcaagg ctgctggtgg agctcgttct
     4501 tatgcagatg ctcttgcctt tgtcgaagca ggtgcgaccc gtatcggaac gtcagctggg
     4561 gtagctattt taaaaggaga attggcagat ggcgactact gagttgattg aactggcaat
     4621 tgaaaccagc aaacatgcct atgtccccta ttctcacttt cctatcggag cagttttagt
     4681 agccaaagac ggaaatgttt acacgggagt gaatatcgaa aatgctagct atcctttgac
     4741 caattgcggt gagagaacag ctatttttaa ggctatatct gaaggccaaa gagaattttc
     4801 agaattgatt gtctatggtc aaactgaaaa accgatttca ccatgtggtg cttgtcgcca
     4861 agtaatggtc gaattttttg aacaagattt aaaagtgacc ttagtcgcaa aagataaatc
     4921 gacggtcgag atgacggtcg gggagttact tccatattct tttacagact taaattagtc
     4981 tgagtcgctc tttgagtggc aagggtcttt gtgaccaatc aatccatact tgcaacatcg
     5041 ttgcacatct tatttaggag gttcagtaat gaacaagaaa caatggctag gtcttggcct
     5101 agttgcagtg gcagcagttg gacttgctgc atgtggtaac cgctcttctc gtaacgcagc
     5161 ttcatcttct gatgtgaaga caaaagcagc aatcgtcact gatactggtg gtgttgatga
     5221 caaatcattc aaccaatcag cttgggaagg tttgcaggct tggggtaaag aacacaatct
     5281 ttcaaaagat aacggtttca cttacttcca atcaacaagt gaagctgact acgctaacaa
     5341 cttgcaacaa gcggctggaa gttacaacct aatctttggt gttggttttg cccttcacaa
     5401 tgcagttgaa gaagcagcta aagaacacac tgacttgaac tatgtcttga ttgatgatgt
     5461 gattaaagac caaaagaatg ttgcgagtgt aactttcgct gataatgagt caggttacct
     5521 tgcaggtgtg gctgcagcaa aaacaactaa gacaaaacaa gttggttttg taggtggtat
     5581 cgaatctgaa gttatctctc gttttgaagc aggattcaag gctggtgttg cgtcagtaga
     5641 cccatctatc aaagtccaag ttgactacgc tggttcattt ggtgatgcgg ctaaaggtaa
     5701 aacaattgca gccgcacaat acgcagccgg tgcagatatt gtttaccaag tagctggtgg
     5761 tacaggtgca ggtgtctttg cagaggcaaa atctctcaac gaaagccgtc ctgaaaatga
     5821 aaaagtttgg gttatcggtg ttgaccgtga ccaagaagca gaaggtaaat acacttctaa
     5881 agatggcaaa gaatcaaact ttgttcttgt atctactttg aaacaagttg gtacaactgt
     5941 aaaagatatt tctaacaagg cagaaaaagg agaattccct ggcggtcaag tgatcgttta
     6001 ctcattgaag gataaagggg ttgacttggc agtaacaaac ctttcagaag aaggtaaaaa
     6061 agctgtcgaa gatgcaaaag ctaaaatcct tgatggaagc gtaaaagttc ctgaaaaata
     6121 atggatggaa gtcatttctt aggaagcggc caagggccgc ttttttaaga gttgagacaa
     6181 agtcattttg tctcagtaaa gcttgctact agacaaacta gcaagtttta ttgaaataaa
     6241 ataagactct gaaaggaaga gcacatggca cacgaaaatg tcattgagat gcgtgatatt
     6301 accaaggtgt ttggtggatt tgttgctaac gacaaaatca acttgcacct acgaaaaggt
     6361 gaaattcatg cacttttagg agaaaatggg gctggtaagt ccacgctaat gaacatgtta
     6421 gcagggcttc ttgaaccaac tagtggtgaa atcgcggtca acggtcaagt tgtcaatctc
     6481 gactccccat ctaaagcagc tagcttggga atcgggatgg ttcaccagca ctttatgttg
     6541 gttgaagcct tcacagtggc tgaaaacatc attttaggta gtgaattgac taaaaatggt
     6601 gtgctagata tcgctggagc tagcaaagaa atcaaggctc tttctgaacg ttatggctta
     6661 gctgttgacc cttctgccaa ggtagcagat atctcagttg gagcccaaca acgtgtagaa
     6721 attttaaaaa cactttatcg gggggctgat atccttatct ttgacgaacc aacggctgtt
     6781 ttgactccat cagaaattga tgagttgatg gctattatga aaaatcttgt caaagaagga
     6841 aaatcaatta tcttgattac ccacaaattg gatgaaattc gagcagtttc tgaccgtgtt
     6901 acagttatcc gtcgtgggaa atcaattgaa accgttgaaa ttgcaggggc taccaatgct
     6961 gatttggcgg aaatgatggt aggacgttct gtttccttta aaacagagaa gcaagcctct
     7021 aaaccaaaag aagtggtttt gtctatcaaa gatttggtgg tcaatgaaaa ccgtggtgtt
     7081 ccagctgtta aaaatctgtc cttggatgtt cgtgctggag agattgttgg tattgcgggg
     7141 attgatggaa atggtcagtc tgaactgatt caagccatta caggtcttcg taaggttgaa
     7201 tctggtagca ttgagctaaa aggagattca attgtaggct tgcacccacg tcagattaca
     7261 gaactaagtg ttgggcacgt tccagaagac cgtcaccgtg atggcttgat tttggaaatg
     7321 atgatatctg aaaatattac ccttcaaacc tactataaag aaccacatag taaaaatgga
     7381 attttgaatt attcaaatat tacttcttat gctaaaaagc tgatggaaga gtttgatgtt
     7441 cgcgctgcca gtgaattagt tcctgcagct gcactctcag gaggaaatca acaaaaagca
     7501 attattgctc gtgaaattga tcgagatcct gatctcctta tcgttagcca gccaactcgt
     7561 gggttggatg tcggtgccat tgagtatatc cacaaacgct tgattgaaga gcgtgataat
     7621 ggcaaggctg tccttgttgt cagctttgaa ttggatgaga ttttaaacgt ctcagaccgt
     7681 attgccgtta tccacgatgg taagattcaa ggtattgtat caccagaaac aaccaataaa
     7741 caagaacttg gtgtcttgat ggctggtgga aacttgggaa aggagaagag tgatgtttaa
     7801 aaaattacaa caaatttcgg ttcccttgat ttctgtattt ctaggaattt tactcggagc
     7861 cattgtcatg tggatcttcg gttatgatgc tatttggggc tacgaagaat tgttctatac
     7921 agcctttggc agtctgcgtg ggattggaga aatcttccgt gctatgggtc ctctggtctt
     7981 gattggtctt ggttttgcgg ttgccagtcg agctggtttc tttaacgtcg gacttcctgg
     8041 tcaggctttg gcaggttgga ttctcagtgg ttggtttgcc ctgtcgcatc cagatatgcc
     8101 ccgtcccttg atgattctag caaccatcgt gattgccttg attgctggtg ggattgtcgg
     8161 agcgattcca ggtattctta gggcctatct agggacgtca gaggttattg taaccatcat
     8221 gatgaactac attgtcttgt atgtagggaa tgcctttatc catgctttcc ctaaagactt
     8281 catgcaaagt acagattcga ccattcgtgt tggggctaat gcaacctatc agacaccttg
     8341 gttggctgag ttgactggta actcacggat gaatattggt attttctttg ccatcattgc
     8401 cgttgcagtt atttggttca tgctcaagaa aacaactctt ggttttgaaa tccgtgcagt
     8461 tggtcttaat ccacatgctt cagaatatgc tggtatttct gccaagcgga ctattatcct
     8521 atctatgatt atttcaggtg ctttggcagg tcttggtgga gctgttgaag gtttgggaac
     8581 cttccagaac gtctatgttc aaggttcgtc attagctatc ggatttaacg gaatggcggt
     8641 tagtttgctt gcggccaact caccaattgg tatactcttt gcagccttcc tatttggcgt
     8701 tctccaagtt ggggctcctg gtatgaatgc ggcgcaggta ccatctgagc ttgtcagcat
     8761 tgtaacagcg tctattatct tctttgtcag tgttcattac cttatcgaac gctttgttaa
     8821 accgaaaaaa caagttaaag gaggtaagta aagatgtcta ttataacctt gctccccctc
     8881 ttggtgtctt ctatgctgat ttactcagca cctctcatct ttacaagtat cggtggtgtt
     8941 ttctctgaac gtggtggtgt ggtaaacgtt ggccttgaag gaattatggt tatgggtgcc
     9001 ttttctggag ttgtctttaa ccttgaattt gcagaacaat ttggagcagc aactccatgg
     9061 ctatccttgc ttgtagcagg attggttggt agtgttttct ctatcatcca cgcagcagcg
     9121 acggttcatt tccgtgcaga ccatgttgtc agcggtacgg tattgaactt gatggcgcct
     9181 gccttggctg ttttcttagt taaagttctt tataacaaag gacaaaccga caacctaagt
     9241 caaacttttg gacgctttga tttcccagtc ttggcaaata tcccagtgat tggtgatatc
     9301 ttcttcaagt caactagtct acttggttat ctggcgattg ccttctcatt ccttgcttgg
     9361 tttattctct ttaagactca atttggtctt cgtctccgct ctgtcggtga acatcctcaa
     9421 gcagcggata ccttgggaat caacgtctac aagatgagat atttagggat tattatttca
     9481 ggttttctag gtggaattgg cggagcgatt tatgcgcaat caatctcagt taacttctca
     9541 gtgacaacta ttgttggacc tggatttatc gcccttgctg cgatgatctt tgggaaatgg
     9601 aatccaatcg gtgctatgct ttctagtctc ttctttggac tttcacaaag tttggctgtt
     9661 atcggttctc aattgccgtt cctacaagga gtgccagcgg tttatcttca aattgcacct
     9721 tatgttttga caattcttgt cttagcagcc ttctttggaa aagcagtcgc accaaaagca
     9781 gatggtatca actacatcaa atcaaaataa gcatacaaaa aacgtcagtt caatgactga
     9841 actgcccccc aaaagttaga cagaaaaaat ctaacttttg gggtgttttt attatgaaac
     9901 taacttatga tgataaagtt cagatctatg aacttagaaa acaaggatat agcttagaga
     9961 agctttcaaa taaatttggg ataaacaatt ctaatattag gtacatgatt aaattgattg
    10021 atcgttacgg aatagagttc gtcaaaaaag gaaaaaatcg ttactattct cctgatttaa
    10081 aacaagaaat gattcataaa gtctgacatg aaggctggac taaagataga gtttctcttg
    10141 aatacggcct cccaagtcgt acgatacttc ttaactggct agcacaatac aggaaaaacg
    10201 ggtatactat tgttgagaaa acaagaggga gagtacctaa aatgggacgt aagccaaaaa
    10261 cgagacctga agagaggaca gaattagaat atcttcaagc agaaaatgag tacctgagag
    10321 cggagaatgc catcctaaaa aagttaagag aactccgatt gaaggaggaa aaagagaaag
    10381 aagaaggaca gaaattgttc aagaattaat gactgagttt tcgttagttc ttcttctaaa
    10441 atccattaaa ctagctcgtt ggacctacta ctatcacttg aaacagctag acaaaacaga
    10501 taaggaccaa gagcttaaag ctgaaattca
//
LOCUS       DAVIME010000062        10361 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVIME010000062 DAVIME010000000
VERSION     DAVIME010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.062"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            31..384
                     /locus_tag="VV588_001898"
     CDS             31..384
                     /locus_tag="VV588_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU7084184.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            599..715
                     /locus_tag="VV588_001899"
                     /pseudo
     CDS             599..715
                     /locus_tag="VV588_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            708..941
                     /locus_tag="VV588_001900"
     CDS             708..941
                     /locus_tag="VV588_001900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084185.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            1069..1211
                     /locus_tag="VV588_001901"
                     /pseudo
     CDS             1069..1211
                     /locus_tag="VV588_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1348..2316)
                     /locus_tag="VV588_001902"
     CDS             complement(1348..2316)
                     /locus_tag="VV588_001902"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU7084186.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(2461..3084)
                     /locus_tag="VV588_001903"
     CDS             complement(2461..3084)
                     /locus_tag="VV588_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU7084187.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSPFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(3066..3275)
                     /locus_tag="VV588_001904"
     CDS             complement(3066..3275)
                     /locus_tag="VV588_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084188.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            complement(3300..3797)
                     /locus_tag="VV588_001905"
     CDS             complement(3300..3797)
                     /locus_tag="VV588_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU7084189.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(3870..5231)
                     /gene="radA"
                     /locus_tag="VV588_001906"
     CDS             complement(3870..5231)
                     /gene="radA"
                     /locus_tag="VV588_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU7084190.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(5245..5760)
                     /locus_tag="VV588_001907"
     CDS             complement(5245..5760)
                     /locus_tag="VV588_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU7084191.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(5762..6205)
                     /locus_tag="VV588_001908"
     CDS             complement(5762..6205)
                     /locus_tag="VV588_001908"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU7084192.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(6262..6359)
                     /gene="ffs"
                     /locus_tag="VV588_001909"
     ncRNA           complement(6262..6359)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VV588_001909"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(6392..6859)
                     /locus_tag="VV588_001910"
     CDS             complement(6392..6859)
                     /locus_tag="VV588_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU7084193.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(7060..8346)
                     /locus_tag="VV588_001911"
     CDS             complement(7060..8346)
                     /locus_tag="VV588_001911"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU7084194.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(8577..8813)
                     /locus_tag="VV588_001912"
     CDS             complement(8577..8813)
                     /locus_tag="VV588_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU7084195.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            9078..9875
                     /locus_tag="VV588_001913"
                     /pseudo
     CDS             9078..9875
                     /locus_tag="VV588_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9910..10119)
                     /locus_tag="VV588_001914"
                     /pseudo
     CDS             complement(9910..10119)
                     /locus_tag="VV588_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10285..10358)
                     /locus_tag="VV588_001915"
     tRNA            complement(10285..10358)
                     /locus_tag="VV588_001915"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10322..10324),aa:Asn,seq:gtt)
BASE COUNT         3340 a         2417 c         1717 g         2887 t
ORIGIN      
        1 atttcaattc actatagaag gaggaaaagg atgattctca gacatctggg aattagcccg
       61 accaatgact tggttgctaa gaaaattttc agcaacccag aaatcacttg tcaatttatc
      121 cgcgatatgc tggacttgcc agccaaaaat gtgactattt tggagggaag taacattcat
      181 gtcttgcctt ccatgcccta ctcagcgcag gatttttata ccagtataga cgtcttggcg
      241 gagttggata acggtactca agtaattatt gagattcaag tccatcatca gaattttttc
      301 atcaatcact tgtgggctta cctgtgcagt caggttaatc aaaatcttga aaaaattcgt
      361 cagcgagaag gtgatactca ctagatctac aaacacatcg ctcctgttta cgtcattgct
      421 atcgtggata gtaattattt ctcagatgac ctggcttttc atagctttag tatgcgcgaa
      481 gacacaacag gtgaggtatt ggcgattacc aacaatggac aggaaaacca tctggttaag
      541 atggcattct tggaattaaa aaatacagag aaaccagcaa agacaaggtt cgcaagccat
      601 ggttggagtt tttcggcaac aagcccttta cccagcaacc gcaacgagcc attagccaag
      661 caaatcaact gctggactac aagagctggt ccgaggagga caggaaaatg tttagtcaac
      721 tacatatgcg agaagaacaa gtcttgttag cacaggacta tgccttggaa actgctaggg
      781 ctgaaggcct tgaacaagga ctagagcgtg ggaaagttga aggaagggca gaaaggaaac
      841 tttttgcctt cctagacata gtacgccaag gtcttctgac ttctgaggtt gccagccagc
      901 aattaggtat gtcagtatct gaatttgagg cactgttgta aaatggctcc ataatatcca
      961 tagtgggtaa atcccctatg gatattatgg agcctatttt gtgtaaaaaa aaaagtccca
     1021 tatgacctat aatgaaaagc gacaaaacaa ctcattagaa agaatcatat ggaacaatta
     1081 cattttatca caaaattact agacattaaa gaccctaatg tccagatttt aaacatcatc
     1141 aataaggata cacacaagga aagcgtcgat tcaaatgcta tcactgttca aaaatgatgg
     1201 tcgctgaaac ttatgatgac gtacagtcat atttcttttc tttttattat atcacagttt
     1261 taaatctagc tttactagat tcaccgctac tatctattta ttcggaaaaa agacgaaaaa
     1321 acctgagaat catctcaggc ttggtcatta aatttttttc tcaatatcga aaagtggaga
     1381 aagtggtcgt ttttcatgaa tacgtacgat agcatcccct aggagatgag cgattgaaat
     1441 ctgctcaatc ttatcaatca aacgctcttc tggcagatag atggtatcca aaacaaccaa
     1501 tttcttaata gctgattttt ggatattgtc cgtagcagga ccagaaagaa ctgggtgcgt
     1561 acagcttgca tagacttcaa cagcaccagc ttccgcaaga gcatctgccg catgacaaat
     1621 cgttccagcg gtatcaatca tatcatcaat caagatacaa gtcttgcctt caaccttacc
     1681 gatgatgttc ataacttcac tagtattcat cttatcaacg ctacgacgtt tatcaataat
     1741 agcgatagat gttttcaaaa attctgccaa cttacgagca cgagtcaccc ctccatggtc
     1801 cgggctgaca accacatagt cagaaccaac cataccacga cgctcaaaat aatctgcaat
     1861 cagaggagca cccatcaaat gatccacagg aatatcaaag aatccttgaa tttgcgcagc
     1921 atgcaagtcg atggtcaata aacgatccac tccagctact tcaagcatat ttgcgacaag
     1981 ttttgaagtg attggctcac gcgctctcgc ctttctatcc tgacgtgcat acccatagta
     2041 aggcatgaca acattgacag attctgcact cgcacgcttc aaagcatcta ccataatcaa
     2101 aatttcaagc agattgtcat ttacaggcga actagttgat tgtaagataa agacgtgttt
     2161 cccacggatt gattcttcaa tgttgacctg aatctctcca tctgaaaatt ggcgaacact
     2221 tgatttcccc aactctatcc caatctcctg cgccacacgt tctgccaatt ctttattaga
     2281 agaaagggca aacagcttta aatcagaaaa agacatgatt tcctccggta tatatgtata
     2341 gcttgtgctt ttcacaagat tttccatcta ccattgtagc gctttttgca ctatttttca
     2401 atcaaaaata aaagaagggc accatatttg tacccttgca tcattctttt gaaaaatatt
     2461 ctaggtcatc aactcattgt gtttctcaac aaagcaataa gcatgataaa aaccatagag
     2521 agcaatagcc gtaaccactg gaatcgctaa aggcaactct gtttccaact ccacaaaagg
     2581 agagttaaac aagaagtgag ttcccaaggc taaacctaga aaaataaggc cctgtttctt
     2641 gccaaccttc tgtcctttat aggctctgta aagcaagtaa acacctacta cagctagacc
     2701 tgaaaaagtc cagtgagagg caattcctga gatgatacgc tctaaaattc gcgaaatagt
     2761 aaagtcaaag ccctctggca aatccgtacg aatataacca atatcctcaa tcatttggaa
     2821 tcccaaaccg gaagcaattc caagtaaaaa caaagatttt aattttcgca caggaatcaa
     2881 agccaaaaca aaaacaagtg gcaataattt caagggttct tctaccaaag gagccacaat
     2941 agcactttca aaggcattta aaaatggact atctgggaaa agaaccccca gtaaatcatg
     3001 gatataagta ttagcaaaac tagacaacca gcctgaaagg aacatccctc ccaataaaga
     3061 cagaatcaaa accttctttg gcaattccca tttttcccaa tacggaagag aaaataaaga
     3121 gccggaatca tgtaaaagag agctagaaag atagaaactc ccattagtcc atattccgca
     3181 cctgacctcg aaccgtccgt atagtagatg gtttcatact gtaaaccaat acatagcaat
     3241 aaaataaaaa taaataaaat actgcttttc ttcatacact ttctttctaa atgaagtatt
     3301 tataattcta cgactgtcat acttcctgta tcaacattgt aaatggcacc agagataatg
     3361 acatcgtctg gtattagggg agactcgata agcagttgca tatcctcgcg tacactctct
     3421 tctatatctt ggaagggcaa gaagtcctgg tctgacacat ctacacctaa ttcctctttt
     3481 aaatactcct gaaaaggttc attttcaaag gtctgagcac cacagtctgt atggtgcaat
     3541 accacaatct ctcttgtccc catttgttgc tgggaaataa ctagcgaacg aatcatgtct
     3601 tcagtcactc gaccacctgc attccgcaag atatgagcat ccccaagtgc caagcccaga
     3661 gcttgcgcaa cgtgcagacg agagtccata caggtcacaa tagctactct tgttttgggt
     3721 ttaagtggca gatttaactg cccatgtagg gcaacataag cctgattggc ttgcataaac
     3781 tgttcaaaat acgacacgat tccctccttg aaaatttgat agtcaaatat ttctcctatc
     3841 ttatcatttt taagagaatt tgtcacggat tatgcaaaga cctttttcaa gacttcctga
     3901 atcgttgtca cgccaatgac ctgaatttcc ttaggcagag tgattcctgt caaggaattc
     3961 ttaggtacat aaatcttagt aaagcccagt ttagcagctt cgttgatgcg ttgctcaata
     4021 cgattcacgc gccgaatctc tcctgtcaag cccagttctc cgacaaaaca ttcctgagga
     4081 ttagttggct tgtctttgta gctcgaagca atagcaactg caacagccaa gtcaatcgca
     4141 ggttcatcca atttaacacc accagcagat ttgagatagg catcctgatt ttgcaagaga
     4201 agccctgccc gtttttccaa aacagccata atcaagctag cacggttaaa atcaagtcct
     4261 gtcgtagtac gcttggcatt tccaaacatg gtcggtgtta ccaaagcctg aacctccgcc
     4321 aaaatcggac gcgtcccttc catggttaca acgatggagg aaccagtcgc cccatccaaa
     4381 cgctcttcta ggaaaacttg actcggattg agtacctcaa ccaagccgcc cgactgcatc
     4441 tcaaaaatcc caatctcatt agtggaacca aaacgatttt tgaccgctct caaaatacga
     4501 aaggtgtggt gacgctcccc ttcaaagtaa agcaccgtat ccaccatatg ctccaacata
     4561 cgaggcccag ccaaggttcc ttctttggtc acatgaccta cgataaagat ggcaatgtta
     4621 ttggtcttgg ccaactgcat gagttcagcg gtcacttcac gcacctgaga aacagacccc
     4681 tgcacccctg aaatctcagg agacatgatg gtctggatgg aatcaataat gagaaagtct
     4741 ggctggatac gctccacttc tgcacgaaca ctctgcatat tggtctctgc atagagataa
     4801 aactcactat caatatcacc taagcgctct gcacgtagtt taatctgctg ggcagactcc
     4861 tccccactga catagagaac tgtccccact tgggacaact gggttgagac ttgtaggaga
     4921 agagttgatt tcccaatccc aggatcccca ccgatgagga cgagacttcc tggtaccact
     4981 ccgcctccaa gcacacggtt gaattcctcc atctccgtct tggttcgatt gacattgatg
     5041 gaagtcacct cagctagttt catgggcttg gttttctcac ctgtcaagga cacacgcgca
     5101 ttcttgacct cggcaacctc aacctcttcc acaaaagaag accaagaccc acagttgggg
     5161 caacgtccca gatatttagg ggaattatac ccacaatttt gacatacaaa tgtcgctttt
     5221 ttctttgcga tgacaaacct ctttctatat ctctaactca cactcaatca cttggcaaaa
     5281 atcaatcttc tcatttggca caaactggcg catgagcatt cgatgagcaa caactaccac
     5341 agtctgatgt tctcgatact tagacataca ttctagaaac cgagacttca tttccgtagc
     5401 tgtctcatat tgaataggac tattaggaag caactccccc ttgttttcta aaaacagtct
     5461 tctagctgtt tcaaaatttt ctattcctgt tttatagacc tgccattcat gtaataaagg
     5521 ctctactctt aaaggaagac ccgtagcaca gaccacatac gaagccgttt ctaaagctct
     5581 tgtgactgca gaagatacga ttatttcagc tgacgagagt aaaggatttt tgctcaattt
     5641 ctggacttgc tgccgtccca tctcagacaa gggtgccaaa tctatcccaa atcctatata
     5701 agaacgctcc tctaactcac ggtaatctgg ctccccatga cgtacaaaga taatcttcat
     5761 tctagtgccc tgtcgatcca aatccaccag ttcgaacgcc atcagctgca tctccatctg
     5821 caattaagaa agtagcaaaa acagcctgga caatacgttc cccaacttca agaacaacct
     5881 cttgatctgt gatattcttc atctgcgcaa aaatatgccc ttcatttcca ggatttccat
     5941 aataatcccc atcaatgacc ccaactgagt taattaaaac caagcccttc ttacgaggat
     6001 ttgaagaacg atcatagagg tagagaacct cagtcggctg catataagcc ttaacccctg
     6061 tcggaaccaa gacaatctct cctggcgcaa caactgtacg cacagcaacc tttaagtcgt
     6121 aaccagccgc atgcgctgtc tcacgcttgg gcaataaatt ttcatctgta aaactcgaaa
     6181 ccaattcaaa accacgaatt ttcataattt tctcttttct attatcattt attctagatt
     6241 attctatctt atttattcgg aaaaagcacg aaaaaaagag cacacaattc aaatcgctta
     6301 gggctgctgg attcctcccc tgacccgctt cacgcagaac tgttgctcca ctatttatta
     6361 tatcacattc ctattcattt taaaagcaaa attatttttt ccgtctattt ctaaaaaaat
     6421 cctgcatgat agctgcgcat tcatcttcca aaattcctat ttcaacctcc acacgatgat
     6481 tgagacgctc atctgtcaag atattgtaca aactcccagc agcgccaaat ttctggtttt
     6541 tagccccata gaccacattt ggaatgcggg caagcccaat cgctccacta cacatgacac
     6601 aaggttcaat ggtcacaaaa agtgtgcaat ccagcaagcg ccagctctcc tcactcaagt
     6661 tcgcatcctc tatagccata atttccgcat gcataaccgc tcgctgtaat tcctcacgcg
     6721 cattatgccc acgaccaatg atttccccat ctttgacaat cacacaacca attggaattt
     6781 catcgtgttc aagagcaatc tcagcctctc tcaaagcctc cctcataaag acttcttttt
     6841 cttcaagcgt ataatacatc tcttttctct tttcctactt atcgatttta ttattatatc
     6901 atgaatccca acacaaaaaa agccaccgaa tgcggtgact ctatagggag attattatga
     6961 aaaagaaaag tttaggatat ttgttacaac aagttaggag gtcttcttgt aaccgtctat
     7021 agtatacccg acctatctta aacaaatctt aaaaatctct taggaccaaa cactttctaa
     7081 aatatttgtt tgttcacgac caggacctac tgagaaagta gaaatacgaa cgccaaccaa
     7141 ttcactcaca cgacgaacat agttacgcgc attctcagga agatcttcca aattgcgaac
     7201 tccggtaata tcttctgacc aacctggcaa ctcttcatag ataggcttgc aacgtttcaa
     7261 ttgctcaaga ctagctggat agtagtcaat acgttgaccg tcaagatcat aggccacaca
     7321 gattttcaca gtatccaaac cgctcaaaac atcaatagag ttcaaagaaa ggttagtaat
     7381 accagaaaca cgacggctat gacgcatcac aactgagtca aaccaaccta cacgacgtgg
     7441 acgaccagtt gttgtaccat actcatgacc cacttcacgg atacgttctc ccacttcatc
     7501 aaacaactca gttgggaaag gaccatctcc tacacgactc gtataagctt tacatacacc
     7561 tacaaccttg tcaatcttgc ttggaccgac accagaacca attgtcacac caccagctac
     7621 agggtttgat gacgtaacaa atggataagt accttggtcg atatctagca taacaccttg
     7681 tgcaccttca aaaagcacac gtttgccatt atcaagcgca tcattcaaga taacagatgt
     7741 atctatcacg tatttcttga tttgttgacc atattcgtaa tattcttcaa aaatatcatc
     7801 gaaaacaatc gctttactgt catacaattt ttcaaaaaga cgattctttt cagcaaggtt
     7861 acgttctaaa cgctcacgga aaatatcttt atctaaaaga tctgcaatac gaattccaac
     7921 acgagcagcc ttgtccatat aagctggacc aattccctta attgtcgtac caatcttatt
     7981 gtcgccctta gcttcttctt gcaagcgatc caactcgata tgataaggca aaataacatg
     8041 cgcacgatca gaaatacgca agttatcagt tgttacacct tcctcatgaa gatagctcaa
     8101 ctcttttaca agagatttag gatttacaac cataccattc ccaatgacag atattttttc
     8161 agggaagaaa atcccagatg gaatcaagtg caacttaaat ttcttaccgt caatcacaat
     8221 cgtgtgacca gcattatcac caccttggta acgtgcaatc acttctgcat tcgctgaaag
     8281 gaagtctgta atcttccctt taccttcatc accccattgg gtacctacaa caacaactga
     8341 agtcataatc ttgtctgagc cctcaggctc ttcctttctc acatacatgg caggactctc
     8401 acctgcaatt atatcttaca atttattata ataaaaaatc gtctttttat caagaagaaa
     8461 caatagaaag atttgctatt tccaactatt aaaaaatgat ttagaaaaat tactagctat
     8521 ttactatcat ctttccataa aagagtaaat tagttcggaa atttactaaa attacctcaa
     8581 caagaaataa aaccccgatt cattaccaat ttttcaagat acaaacgata agcaacacga
     8641 taatggtaaa caataaaatc cttacgacaa ccaatgccat atctcactaa ataataaatt
     8701 aaaaatttaa aatgaacatg ttcccagtca aaattatcac caaatgtagg accatactct
     8761 tcttcaatac tatcatagaa attagccatc tgctcataaa ttttttgtaa cataatcaaa
     8821 tactcctttt cttttttata aacttattct aacaaaaaat tttacacatt cactatcaat
     8881 tcctgaattg ttaaaatacc agcctcaaca agataaaaat aggaaaagtt gacagaatag
     8941 aaacaaattt gctacctaaa tttcaaacga ttaaagttct aaaaagaccg ccttaaaact
     9001 tttgggtaaa tcctattaga actataatat ttttatatag gtattatggt tctgattttc
     9061 tagtataaaa aattcaaact agaattcttc ttagaaaagg ccgttttaag tgctatcact
     9121 gttcaaaaat gagggtcgct gaaacttcta tcgtcaagaa gaatcatcaa attccttgta
     9181 tcatcaacca aaagattgct cagaagctaa ttaaaaagac ttctatgacc gacattgatc
     9241 atcagttgtc tatttcaact tcaactgtca ttcgcaagat caatgatttt cactttgagc
     9301 atgatttttc gcgtcttcct gagattatgt cctaggacgt tgaaacagtc cggggagtga
     9361 ctgtttcaat cgggagatgg agatgagctt tattgctcaa gactttgata agctcaatat
     9421 cataactgtt cttgagagca gaacacaagc catcatccga aatcccatga atacaaggct
     9481 atcaagcgat actgaaagct cattcaacaa gatagtcaga aactgagtga taaacgattt
     9541 tatcgcccta cttttcgtat gcacttgact aataaagaaa ttctagataa acttttgagc
     9601 tattccgaag acttgaaaca ccactataat ctctatcagc tcttgctttt ccacctcttt
     9661 ttcagactct gtttaaaacc ttcctcaaag ataaagagaa aatcgtcaac gcccttcaat
     9721 taccttattc caacgccaaa ctggaagcca ccaataatct catcaaactt atcaagtaca
     9781 atgcctttgg ttttaggaac tttgaaaact tcaaaaaaga aaggacgaaa tttgtccttt
     9841 ctagatcttc gctttcttca acccactaca gttgacaaag aaccgaaaaa tgtctcgcct
     9901 ctaatatagt caattgaaac aagaacaaga caaaagagcc tcataaaagg tattgcaact
     9961 tgctaatacc tttttggggt tctttttgat atgaacccat gttttctcaa taggattgta
    10021 ctcaggtgag tagggaggaa gaggtaaaag tttatgccca aactcttcac acaagagttc
    10081 tagcttaccc attctatgga atcttgcatt gtccataata tagtagattg aaactagaat
    10141 agtacacctc tacttctaaa acattgttag aattcgattt tactgtcctg atcgatttgt
    10201 cctattctta tttcatttta ctataacacg aaatagatta ttattacata acaaaaaaga
    10261 ggtctaaacc tcttaactaa attactccgc cagtaggact cgaacctacg acatcatgat
    10321 taacagtcat gcgctactac caactgagct atggcggatt a
//
LOCUS       DAVIME010000063         9507 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVIME010000063 DAVIME010000000
VERSION     DAVIME010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.063"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            1..1207
                     /locus_tag="VV588_001916"
                     /pseudo
     CDS             1..1207
                     /locus_tag="VV588_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="serine/threonine protein kinase"
     gene            1221..2138
                     /locus_tag="VV588_001917"
     CDS             1221..2138
                     /locus_tag="VV588_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084196.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            2135..2935
                     /locus_tag="VV588_001918"
     CDS             2135..2935
                     /locus_tag="VV588_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7084197.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            3093..3566
                     /gene="tnpA"
                     /locus_tag="VV588_001919"
     CDS             3093..3566
                     /gene="tnpA"
                     /locus_tag="VV588_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEU7084198.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVSSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            3823..4044
                     /locus_tag="VV588_001920"
     CDS             3823..4044
                     /locus_tag="VV588_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7084199.1"
                     /translation="MYRRLRDLREDHDLTQKQIATILSFTNSAYAKIERSEHALTADV
                     LVKLSDFYDVSTDYLLGLTDFPDKIRFRK"
     gene            4346..4579
                     /locus_tag="VV588_001921"
     CDS             4346..4579
                     /locus_tag="VV588_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU7084200.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            4655..6163
                     /locus_tag="VV588_001922"
     CDS             4655..6163
                     /locus_tag="VV588_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU7084201.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKRESRKRLDAKFLAIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRTIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFKHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            6244..7095
                     /gene="ylqF"
                     /locus_tag="VV588_001923"
     CDS             6244..7095
                     /gene="ylqF"
                     /locus_tag="VV588_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU7084202.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEKAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            7082..7861
                     /locus_tag="VV588_001924"
     CDS             7082..7861
                     /locus_tag="VV588_001924"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU7084203.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            7877..9427
                     /locus_tag="VV588_001925"
     CDS             7877..9427
                     /locus_tag="VV588_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU7084204.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         3147 a         1503 c         1867 g         2990 t
ORIGIN      
        1 atatcaccca atctaaggga tttaaaatac acctgagcgc ttcaatatta aatgctaatt
       61 tggttgctaa aaaattcttt gattttatat tttctagaga gaagaagata aatttcaaaa
      121 ttttggttag cattaaagaa ctttctttgc aaaatacagg gcttaatggt tattcacaag
      181 tcgggaaatt cattacaatt tatccaaaag ataataaaga gtttcaacgt ttgttacaca
      241 aattagaaat attgtataaa ggtgtaaagg gtgtaaacat accatcagat ttcaacttag
      301 cgaggttgta tattacagat atggggagtt cgtaaaagat agcactttca aggataaaag
      361 agataagaaa atcccttcaa atgtgaatgt tccaataagg gattactata ttccaagata
      421 taacactatt cctgatcaat atattatttt ggaagtgatt tctaaaaatg ccaaaggtgg
      481 agtttataaa gtatttaata ctcaaaagcg agtttattct ttattaaaag aagctagtga
      541 tttatcgttg gttgatttta caaatagaga ttctgtgaat cgtttaataa atgaaagaga
      601 aatattagta gaattggaaa aggaggaatt tactccaaaa gtttttaacg atttttacat
      661 aaagaattcg tattttgtgg aatttgagtt tattattgca gataaattaa gcgagtataa
      721 tatggttagt ggctcgtatg attggttttt aacattaatt gattatatgg agataataaa
      781 ctccaaatat aatctttcct atagagattt atcatttaat aatatactta ttgataatag
      841 aaataatatt tatattatag actttgagca tgccctaagg aaagaaactc aaattgaaga
      901 aaaaaagttg cctctatttg gaactccagg gttttatgaa accaacttaa atttattgaa
      961 taatcaacca gaggatatta tgggattggt tttgttatta tattggagtc agaatttaga
     1021 tgattttaac gtcttttcaa aaatgagttt tttagaagcg atggagtatg caatgaattt
     1081 taattcgcgt cgcttagaca cacttgataa atcagattgg ctttatgata tttataaaaa
     1141 agcgttcaat tataaatatg atactttttc tgaattaaaa aaagatttta tagaggtatt
     1201 aaaataaagg taggggtgtt atgaattgtt tcttgaaaat gaataatgta agtgttcgtt
     1261 atgatgacgt aatagcttta aaagatataa ctttacaaat aaataaggga gatttcattg
     1321 gcttattagg ttcaaatggt gcaggtaaat ctacgttaat taattctatt gtaggttttc
     1381 aagagattta tttaggagaa atagagtatt gtgataaaga tttgatagtt agttctcaac
     1441 cttttgctca tttaggcttt actcctcaaa ccacagtaat tgatttttat actactgtga
     1501 aggacaatgt aatattgggg ctgaaccttg ctggaaagtt tgggaaaaat gctgagaagt
     1561 tgtgtcaaat agccttagaa attgttgggt tagctgataa aaaaaataat ttggtagaaa
     1621 cattgtcagg tggacaactg caacgcgtcc agattgctag agcaatagct cataatccag
     1681 atttttatat tttagatgaa cctaccgttg gtttagatac tgaatctgcc gaaaaatttt
     1741 taatgtattt aaaagataag agtttggaag gaaaaactat tatcatatct tcacatgaca
     1801 taaatctact cgaaaagttt tgtaaaaaaa tacttttttt acaaaatggc tccatatcat
     1861 tttttggtga tatgcgtgac tttgtagata attcaactat caaattaaat ttttcaatgc
     1921 agaatagaat ttctagatat caaattgaat ttttagaaaa ttttagattt aaagttcaca
     1981 tcgaagataa tgatagtttt acaatagaag tccctataga agaaaatatc ttagatgtta
     2041 tcaatgaggt aggaaaagca tgtgaaatta aaaacttttc aacaagtaaa ttaaccttac
     2101 aagaaagtta tttgcaaaga ataggaggag aaaaatgaag gctgatcaat taaggcacaa
     2161 atcggactta ggtttaagag gtctagcgat tattgctaaa aatgagatta ttgctttttt
     2221 tagaagtaaa ggtttaatta tttctcagtt tctacaacca atcttatatg ttgtttttat
     2281 aataatagga ttaaattctt cgataaagaa cattcagttt aatgatataa aaacctctta
     2341 tgcagaatat acaatcattg gtgttatagc tttattgata atcgggcaga tgactcaagt
     2401 tatttatagg gtgacaatag ataaaaaata tgggctactt gctcttaagt tatgcagtgg
     2461 agttcgtcct ttatattata ttttagggat gagtatctat tctatattag ggttgatagt
     2521 tcaagaaatt attatatata taattacgtt agcgtttgag ataaatatcg caatggatag
     2581 atttttttat acagttttgt tatctattgt tgttttatta ttttgggact cccttgcaat
     2641 tttacttaca atgtttatca atgattacag aagacgtgat attgtaatac gttttgtact
     2701 aacaccgctt ggttttacag ctcctgtttt ctacttaata gattctgctc ctagtattgt
     2761 gagatggatt ggtcagttaa atcccttaac ttatcaatta actattttga gaaactttta
     2821 ttttaaaaat tcaacaactt tggaattagt tttcttattg ttaacatcat tacttgtcct
     2881 tatatctgta tcttttatta taccaaagat aaaattgata ctgatagaaa gataaaagtt
     2941 gggtcatcca acttttttgt tgtctcccga aaaccactag ctatgctagt ggttccatag
     3001 agcttttagc gtggtaacaa aaagaacctc ctaaaatgat aagatagaag tggtttctcc
     3061 gccactacaa catatcatac aggaggtacc tcatgagaga ggataatcaa agtttatcac
     3121 ataccacatg gaattgtaaa tatcatattg tttttgcacc caaatatcgt cgtcaaatca
     3181 tttatggcag atacaaagct agtatcggaa gaatcatacg tgacttatgt gagcgtaagg
     3241 gtgtaataat ccatgaagcg aatgcttgtt cagaccatat tcacatgctt atcagtattc
     3301 ctccgaaact tagtgtttcg tcctttatgg gctatttaaa gggcaagagc agtttgatga
     3361 tttttgataa gcatgcgaat ttaaaataca aatatggcaa tcgcaagttt tggtgtagag
     3421 gctattatgt agatacggta ggccgtaatc agaaagtgat agctgaatat attcagaatc
     3481 aattacaaga agacagagta gcagaccagc tcacgttatt cgagtcagta gatccgttta
     3541 ctggcgaaat aaataagagg aagtaactaa ggtgctttag cacctgctcg ggaaagtggt
     3601 gcgcgaggaa gctatttcgg tgggcctttg gccctggccg gtagaagcgg cttatagccg
     3661 cagaacaaac caccagttca cactggtggt tttgatttaa aaaacttgat acataaaaat
     3721 aaaagtctat ataaaggatg gtaaaattcc tgttgtccga tttggacaat atcctaaata
     3781 gttacaatat atggtctata ctttttctta ggagaaagct agatgtacag acgtttgaga
     3841 gatttgaggg aggatcatga tctgacccaa aagcaaatag ctacaatact ttcgtttaca
     3901 aattcagctt atgccaaaat tgaacggagt gagcatgcgt tgacggctga tgtattggtt
     3961 aaactctcag atttctatga cgtcagtaca gactatttat tgggattaac tgattttcct
     4021 gataaaattc gctttagaaa ataatctcct caatttcata gagtttgaaa atgagtgaga
     4081 ttttttattt gccctttgac aactgaatag cctaaaatgg tactttcctc atttgtggag
     4141 cagttttgct tgattcgcca agataggagc ggggacaatc accaataaaa tagagcgata
     4201 ctctatctgc catgatgcaa atgatataca atgatacttc tgaacgttca ggctgccgtc
     4261 gtaaaagagc agtaagtgag attcttatga tgaccccatc agtcatgcca tggagggaga
     4321 agaaattatt cgaaaggatg ataatatgga gataaaatac gtatctgttg aaaattcggt
     4381 agctgagtgg gcggataaga aaagcatact gaaacgatgg gaaggtttga atctctacac
     4441 tcttaacaga tggatcaaag aaatgagaga aaataagaga ttttctttat acgtcatcaa
     4501 tcctacacat aagctggtgt ttataaatct tgagggattc gaatgctttt tgagatggaa
     4561 acaaaagcgg acaaaataag gaagtcatgg tataatatag agtagttatt tattctatac
     4621 aacaatgatt tatttctttt cgaggaatta aattatgtat tatgtaacta aaacaaattc
     4681 aaaaggacaa cccttgtatc aagtggttga aaaatataaa gatccactta ctgataagtg
     4741 gagaacagta actgtcagct atactagaaa tactagtaga gcacgaaagc aagctgaaag
     4801 agaggtaatg gataaaatag aaaaactgac ctcttccctt gaaagtcagt acaatcctga
     4861 aatgattaca acttttggag agttaaaaga gagttggttt caaacttggt gcgtatctgt
     4921 caagccccag acaataaaaa gggaagagtt ggtgatagaa cggcttggta aaattatcgg
     4981 tgatgaattt ttactcgatc gaattacacc actactgatg aaaaattgtc ttaataaata
     5041 tctggataaa tacgacgctt caccttcaac aatgacacat ataaaaagta cgtgtaacaa
     5101 gatatttaat cacggtgtgc tatacaatgt cattaagtac tctccaatga ccgctgttaa
     5161 aatagatgtg cctctggaga aaaagagaga atcaagaaaa aggcttgatg ctaaatttct
     5221 tgcaattcat gaattgcaag ccttttttga tgttttaggg cagtgtagaa atgctagcta
     5281 ttatgacctt gctattgtat tattactgac agggattcgg attggagagg ctgctttttt
     5341 accatcagat gttgattttg ataaggggat tttacatatt gataaggctc tccaatatca
     5401 tgatttaaaa gttgatgaat tttattttga tacgactaag accgtcaatg ctgatagaga
     5461 ggtagccctc ccaatagcag cgagtgaagc aatccagaga actataaaaa gaaatcagga
     5521 atttgaagcc tatatggaac aaaatcctag tcctgctttc aaaaagtgtg atagtgtatt
     5581 tcaaactgag tatggttctc cgataacttc tcactcattt cgtcaagttt tgaagagggt
     5641 tgaggagaag ttgttaaaaa attgtcagaa ggattatggt tttaaatggg tcaagcatgt
     5701 gacccctcat tctttcaaac atatgcacat tagttatctt caaagtaatg aaatgcacat
     5761 agctgtaaag gatattatga ctagagttgg tcatgcgaat tttgaaacca cgatgggcta
     5821 cacccataac atcagtcgtt cacaagaaaa tactgtaact gctttaaatc aatttgtaga
     5881 aaagcacaat tttcacttta aagaattgaa gagttacacc tgtaaatatt cgagaatgat
     5941 tgaacaattc attgaaactt gtgatgataa caataaagta gagttaagtg ttgatgaatt
     6001 taaagactta ttacaccttg gttcacgtta ctcacccaaa catattgttt caaatttact
     6061 gttaaaaatc aaaaaagata ttgtcaaata tcacccacag tttgatataa agattgtgaa
     6121 attaagcggg aatcaaatca aaggtttttc catttcgtgg tagttttggt gttcgcttgg
     6181 tgtttagacg atagtaaaat aaatgagggg tgctaaaccc ttgctacgaa aggaaaaaac
     6241 tcaatggcta ctattcaatg gtttcctggt cacatgtcta aagctcgtcg acaggtgcag
     6301 gagaatttaa aatttgttga ttttgtgacg attttagtag atgcacgctt gcctctatct
     6361 agtcaaaatc ctatgttgac caagattgtt ggtgataaac caaaactctt gattttaaac
     6421 aaggccgact tggctgatcc agcaatgacc aaggaatggc gtcagtattt tgaatcacaa
     6481 ggaatccaga cgctagctat caactccaaa gagcaagtga ctgtaaaagt tgtaacagat
     6541 gcggccaaga agctcatggc tgataagatt gctcgccaga aagaacgtgg gattcagatt
     6601 gaaaccttgc gtactatgat tatcgggatt ccaaacgctg gtaaatcaac tctgatgaat
     6661 cgtttggctg gtaaaaagat tgctgttgtt ggaaacaagc caggggtcac aaaaggtcaa
     6721 caatggctta aaaccaataa agacctggaa atcttggata caccggggat tctctggcct
     6781 aagtttgagg atgaaactgt tgcacttaag ttggcattga ctggagctat caaagaccag
     6841 ttgcttccta tggatgaggt taccattttt ggtatcaatt atttcaaaga acattatcca
     6901 gaaaagctgg ctgaacgctt caaacaaatg aaaattgaag aaaaagcgcc tgtgattatt
     6961 atggatatga cccgcgccct cggtttccgt gatgactatg accgttttta cagtctcttc
     7021 gtgaaggaag tccgtgatgg caaactcggt aactatacct tagatacatt ggaagacctc
     7081 gatggcaacg attaaagaaa tcaaagaatt ccttgtgaca gtcaaggagt tagaaagccc
     7141 tattttttta gagcttgaaa aggataatcg ctcaggagtt caaaaggaaa tcagcaagcg
     7201 taaaagagcc atccaagctg aattagatga aaatttgcgc ttggaatcca tgctttctta
     7261 tgaaaaagaa ctttataagc aaggattgac cttaattgca ggtattgatg aggttggtcg
     7321 tggtcctctt gctggtcctg tagtcgctgc ggccgttatt ttacctaaaa attgtaagat
     7381 taaaggtctc aacgacagca agaaaattcc taaaaagaaa catctggaga ttttccaagt
     7441 cgttcaagac caagccttgt cgattggaat tggtatcata gataatcagg tcatcgacca
     7501 agtcaatatc tatgaagcaa ccaaactagc catgcaagaa gcaatctccc agctcagccc
     7561 tcaaccagag caccttttga ttgatgccat gaaactggac ttgcccattt cacaaacctc
     7621 cattatcaaa ggagatgcca actccctctc tatcgcagca gcatctatag tagccaaggt
     7681 aacacgtgat gaattgatga aggaatacga tcagcagttc cctggctatg atttcgctac
     7741 taatgcagga tatggcacag ctaaacatct ggaaggcctc acaaaactag gagttacccc
     7801 aattcaccga accagctttg aacccgttaa atcactggtt ttaggtaaaa aagaaagtta
     7861 attgaaagga aataccatgg aggaacaatc ggaaatagtc cgttctaaga aagaattcgc
     7921 ctttgcatcc agcactatac tatcccaagt tggtcgagga atcattgtcg gcctcatcgt
     7981 tggaattatc gtcggatcct ttcgtttctt aattgaaaag ggcttccacc tgatacaagg
     8041 agtttatcaa gatcaagggt acttagtgcg caatcttttt gtactggttt tgttttatat
     8101 actcatctgt tggctcagtg ccaaactaac acggtcagaa aaagatatta aaggctcagg
     8161 aattcctcaa gtcgaagccg aactgaaagg cctcatgtcc ctcaactggt ggggcattct
     8221 ttggaaaaaa tatgtgctag gtattcttgc tattgccagt ggactcatgc tgggtcgaga
     8281 gggacccagc attcaacttg gagcagttgg tggtaaagga attgccaagt ggctcaaatc
     8341 cagtccagta gaggaacgtt ccttgattgc tagtggagct gcagcaggtt tagccgcagc
     8401 ctttaatgct cctattgcag cacttctctt tgttgtagaa gaagtctatc accatttttc
     8461 gcgctttttc tgggtctcaa ctctagcagc cagcatcgta gcaaactttg tgtctctact
     8521 catgttcggt ttgacaccag tattggatat gccagataac attcctccca tgaccctaga
     8581 ccagtattgg atatatctcg tcatgggaat tttccttgga ttttcaggtt ttctctatga
     8641 gaaagctgta ttaaacgttg gaagagttta tgacttgatt ggtcaaaaaa tccatttgga
     8701 tagggcttat tatcccatct tggcttttat ccttatcata ccagtcggaa tcttcttacc
     8761 tcaaatcatt ggtggcggaa atcagcttgt cctttcttta actgaacaaa attttagttt
     8821 ccaagtttta ttagcttact ttttgatccg ctttatttgg agtatgatta gctatggaag
     8881 tggactgcca ggaggaattt tcctccccat tttagctctt ggttctttgc ttggtgcctt
     8941 agttggtgtt atctgtgtca atcttggact tgtcagtcaa gagcaattcc ctatatttgt
     9001 cattctagga atgagtggct attttggagc catatcaaaa gctcccttaa ccgctatgat
     9061 cctcgtaact gagatggtag gagatattcg caacctcatg ccacttggtc ttgtcactct
     9121 tgtttcttat attatcatgg atttgctcaa aggtacgcca gtctatgaag ccatgctgga
     9181 aaaaatgctt ccagaagaag tatctagcga aggagaagtt acacttatcg aaataccagt
     9241 ttctgataaa attgctggga aacaagttca tgaactcaac ttaccacaca acgtcctcat
     9301 cacaactcaa gtccataatg gcaagagcca aacagttaac ggctcaacca gaatgtatct
     9361 gggtgatatg attcacctgg ttattccaaa aagtgaaatt ggaaaagtca aagatttgtt
     9421 gttgtagtat gagcatttac ataatttatg ttatgtaaat gctcagcttg atttatttag
     9481 aaaaccgatt ctcagaaatg agatcgg
//
LOCUS       DAVIME010000064         9350 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVIME010000064 DAVIME010000000
VERSION     DAVIME010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9350
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.064"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..187
                     /locus_tag="VV588_001926"
     CDS             <1..187
                     /locus_tag="VV588_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084205.1"
                     /translation="VALLYHKITEYVNNRKIDIVIFLSLLISHFIWNYYFLPIEILIA
                     ISGANLLLSFLKKLQTK"
     gene            1069..2127
                     /locus_tag="VV588_001927"
     CDS             1069..2127
                     /locus_tag="VV588_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084206.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2442..3419
                     /locus_tag="VV588_001928"
     CDS             2442..3419
                     /locus_tag="VV588_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084207.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLISFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKQFKKINNPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            3796..4170
                     /locus_tag="VV588_001929"
     CDS             3796..4170
                     /locus_tag="VV588_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU7084208.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4378..5280
                     /locus_tag="VV588_001930"
     CDS             4378..5280
                     /locus_tag="VV588_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084209.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHLLVSNLQLNLEIPLDFVVSTSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5336..5668
                     /locus_tag="VV588_001931"
     CDS             5336..5668
                     /locus_tag="VV588_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU7084210.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            5665..6393
                     /locus_tag="VV588_001932"
     CDS             5665..6393
                     /locus_tag="VV588_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084211.1"
                     /translation="MNNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSSWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            7526..7765
                     /locus_tag="VV588_001933"
     CDS             7526..7765
                     /locus_tag="VV588_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084212.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            7750..8028
                     /locus_tag="VV588_001934"
     CDS             7750..8028
                     /locus_tag="VV588_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084213.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            8317..>9350
                     /locus_tag="VV588_001935"
     CDS             8317..>9350
                     /locus_tag="VV588_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEU7084214.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVAKQSQAER
                     DYDAAMKKSEAAKKEYEEAKKDLEEAKAAQKKYEDDQKKTEEKAKLVQKADEERQKAN
                     VAVQKAYLKLREAQEQLNKSPNNKKNAAQQKLKDALAHIDEVTLKQKEAEANFNKEQA
                     KVVPEADKLAETKKKAEQAEKKEPELAKKVAEAKAKAEEAEKKAVEAKQKVDAEKYAL
                     EAKIAELEYEVQGLEKELKEIDESDSEDYIKEGLRAPLQSKLDAKKAKLSKLEELSDK
                     IDELDAEIAKLEKDVEDFKNSDGEQAEQYLVAAKKDLDAKKAELENTEADLKKAVDEP
                     ETPAPAPKPAP"
BASE COUNT         3207 a         1209 c         1699 g         3235 t
ORIGIN      
        1 tgttgcatta ctgtatcata aaattacaga gtatgtcaac aacaggaaaa ttgatattgt
       61 tatttttcta tcattgctga tttctcattt tatttggaat tactattttt taccaattga
      121 aatattgata gcaatcagtg gagcaaattt actattaagt tttttaaaaa aattacagac
      181 taaataatat taatctgtgt aatacagtag ctcggtcatt agattctatt gaagatataa
      241 attaaaaatg aggctgggaa aaaactcaat ttgaaaatga gattgagtaa atctttctat
      301 ctatataacg tatatcatca atatttttga acacctgata atatgcattt ttcttatttt
      361 aaagattttt tgcctttctt catttcttga atgaattgga gagatgactt tatttaggtg
      421 tttgacatta ctatagatag gatttagcag tactaatatg aactcatatt ataggtgtag
      481 acttaaattt tggaagcaag ctaaaggata tcttatctag gtaactaagt gctataacaa
      541 gatatattgg tggagttagt atggcaacta ttactaatgc tcttaatatt gcggctactg
      601 ttgctgaagt cttctcatta ggaggagcca ttgcatatgg tttagatatc gtagacggta
      661 aatttgatgg gtatttatgg gcgtaaaact atagctatga aacatttttt tgcaggaatt
      721 ggtgaaattc attttttgtt atttttatta tatctaagca tgtctgctag tccaattatt
      781 ggactagtga ttggatatac taaaataaat ctaataaatt ctattattat agctcttggt
      841 atgatattgg cattaatttt ggtattatca agagtgtata gaaaatattt ttatagagac
      901 gatgatgact aaagttttta tcaataattt gggctccttg tcaactgtag tgggttgaat
      961 aaaagctaac gtctggggaa gggtttaaag ctttgcttta tcaaatattg acttacagag
     1021 ttgctctatt gtattgatgc attcttagta aataatatgg tgttttgaat gaaagatgat
     1081 cagaaatatt tattagcggg actttattcg cttctagttg caatatttta ttttccattg
     1141 attgattcca aggggatttt tgtaagtata ttgatggcgg ttttactttt atatttaata
     1201 tacttcattg caacagtcat tcatattgtg ataattaagt ttataagaaa aaaatctttt
     1261 aagtatttgg ttctatatcc atttacttat gatgggagct ggagatttca acctataaac
     1321 ttactctact ttccagaaat ggtgagagat gtcattccga ttaatttagt tcaagaatat
     1381 tgccaaggac aaccttacgg actgttaaaa aagatgctga aaagaattcg attgtcacga
     1441 gagatatctt tactcctggc taccattatc gtctattttt ttacgcatag aattctacct
     1501 ttttcagtat ttacgttcat gttttcttat atattgctat ttgtacaatc ttatttgggt
     1561 ggtaataccg cttggattgg aaatagaaga ttaataatag atgatgaatt tgaaaaaatc
     1621 ttgctttcaa aaagttatat aaaagaaata tcatctgcac gatactcaga atacttgaca
     1681 tgtgaataca aaaactttac accaatcata ttgttagcta tttttgaaaa tttgcttgac
     1741 tcctacttgc ttcagaatca gagtgaggtt gacttagata ttttttataa agttttacct
     1801 ttgctttata aagaaaaata tactatggga ttcaattact ttgtaagttt aaattattta
     1861 ctatataagg ttggattttt gggaatcatt tacgataatg aagcattaag agatttgtca
     1921 aaacaatatt taaacaaaaa tatttcggaa ttacaagatg gttctttcga gggcggtata
     1981 caagatgctg ttgcctctaa acaaatagta gttataaatg aatttatagc ttgtttaaat
     2041 tccagatgca tgccatccca atatgataga tttttttata aagatagacc ttatattttt
     2101 tccagaaaga gtcctattaa ggggtgaaaa tttgttacat ttggattaac aagtgtccta
     2161 gggattagaa ataactctag tatagctaga tatttttgag taactagaaa tatcattagt
     2221 ctacccatat gattgccaga aaagatggct gatgaatctt atttatactg ttgcagtagg
     2281 cgttgtctag gataaataag ctatcttgat gggggagatt ggaataattt tagtagaaac
     2341 attaaaggat tatggacaag tagcgtagga ttaggtgatg caatgtgcta agttggcttg
     2401 gtgttaacag tagtattatt taacaatgga aagtagacta aatgaaaaat aagcgttatt
     2461 tttttgacac aattttaata attttactgc ttataagcac gatattttgt gtcagcccag
     2521 tatttataaa attggacatc ttaggaactc cctctcatgc catcttaacc tttgtattgg
     2581 cgataccgtt attctatatt ttgtctcaat gcttacatac tttgctatta ctagtttcct
     2641 caatcttttg taaattaaga ccaatttatt tttattttat atttgtgatc attataggag
     2701 ctaggaaata ctatcgaatt ctctttcacc aactaatggg atttagtcca ggaatagcag
     2761 tgttttataa ggagagtcaa acaactaaga atctgtttaa attttactac ttcttgtact
     2821 ttacaacact aatttcatac tattttttct ttacttttgt gtatgacaaa ccgttgcttt
     2881 tgcctcttat ttcattttct attatcatag cattagtaca aaaactttat agaattgaga
     2941 atcaacaatt atttctgtta aaatcaaagg tactaacaat actggaatct aagaagaatt
     3001 gtgagtttaa tcttcaggat tatcatgaaa tttggaaatt gcaatcaaaa tctgagttgc
     3061 catgcgtggc tttatcttat atcagtttaa tcaagccata tctttcagag agtgtgcgtg
     3121 aacaaattga tttattagaa gttaagcaat ttaaaaaaat aaataatcca atatcacttt
     3181 atggtatgtt ggatgttata aaattaaatc tatatttacg gcattataat gaaaaaaata
     3241 aatatgaatc aatgttaaag aaaattttag aggtaagacc agactttgtt ttaatcgagc
     3301 agaatattga tgatagttta aatagctcgc aaccattatc tttatcttta gccatttcag
     3361 aaatccaact tttgcttgaa gtgtatatag ggatcaaaca tgtttcaatt aggagataaa
     3421 actagaataa tatttgccat tataggggca agttgcatat tagtcagtat gtatcttatt
     3481 ccacttatta aaactgagaa taaattttgg gaaatacttt tatttatatt aggtgtattg
     3541 ctaattggaa ttgcgttact aagtcaaaaa aaataaattt tgaaatagta ttagtgagtt
     3601 cgcaatcatt tattgctagt ggtttagaac tgttaagttt caaacaataa ttgattttaa
     3661 accttaggta acctataaaa acaaataagg tagagaaagg atatcttatc taggtagcta
     3721 agtgataaaa acacagtcgt ctatcacttg ttaggaaacg atcctaacta tgcttaataa
     3781 aaaaggagaa aataaatgga actcgtatta ccaaataatt atgttgctct tgagcaagaa
     3841 gagatgatgt atcttgatgg gggattttct attctgagat ggcctgttgc aacagccatt
     3901 aatatagctt ttaatggtgt tttaggtgga ggagcaatca gtctagttag aaattatatt
     3961 cgtaattatg gtttgcggcg agttacaagc gcaattgctg gagcagctgc aagatatgtt
     4021 ggggtacgag ttgcaaatag agtggcagga tttgcactgt ctgctattaa tggatttgca
     4081 gcttggatgt caattggcga tgctattaca acaatctggg ccaacaatga tgtaaatagg
     4141 agagacccaa atttaaacgc cttgtggtaa ctagatatgg gtattaaaat ggaaaaaatt
     4201 tttgttatta ttttttttgt atgtctattt atatcatcca taactttttt agcctatgat
     4261 tttgttagcg aagaaataaa aaagttgatt atttggatga atgtcgtttt tttgatttta
     4321 atcatagcaa tgataattta tccaaaatta agaaaatgat aaggacactg taaaattatg
     4381 atacgtaaac taatcatttt tttattaatg ctccctcttt ttgtcttgtg gctagagttg
     4441 catttgttag tgagtaactt gcaattgaat ctagaaattc cccttgattt tgtggttagt
     4501 acgagtcttg ctttctgtag tttgatttta tcaaaaatag ttttagacat actatacgca
     4561 ttgaaagatt tgtacaagaa agaagctctt attacgattt ttccttttat ttttataggc
     4621 aggaagaaag taaatgtgag gttctcgccc tatttttcat tccatcgtaa aagtttgtcg
     4681 cctgatgatt taagatctag gattatatgg agttttattc ttgaaattgc tattattcta
     4741 gtatttattt taaaaattcc ttttgcaatc atcatgctta ctacaatatt tttctggact
     4801 ataatggata tcaatcatct cgtttttaat aagacggaat ttctttttaa tcaaaataaa
     4861 tgggaaaaag aagattcgtt tgaaagcgat ttgacgaaaa cgttaaagga taagatacaa
     4921 aaatcagagc taagttattc tgacttaatg tctcttcagc tgtatgatgc gatgaaccaa
     4981 tccacctttt taacggatag tgaacttttt gaggatattt tgaaaaaaat cgaagattct
     5041 cataacaccc ttctgtgtac aggtcttgtc gagttactgc tgtatgaaat gtctattagt
     5101 aacaataaca actggtccaa caaggttgat aaaattagga tacacctcat cagaatcaat
     5161 caattagatt ttttctatta tacaagttgg ttaaggcaaa attttgattt ctgtatgaat
     5221 agagagtatc ataaaatgaa atctcggaaa ttattactga gtaataaaaa gatagtttaa
     5281 gttcgtccta tttgtaaaac aaatgaaaca atttcaacta aggaggagaa aacaaatgga
     5341 acttgtatta ccaaataatt atgttgtgat tgatgaagaa gaaatgatgt atcttgatgg
     5401 gggagcttat ttaagcaagc gtgcttgtca aggaatttgc gtagctttag ctatgagttc
     5461 aggaactttt atagcattag ctggagctgc agttttaacc aaaaaactaa taaactatat
     5521 taaggttgga ggtcttggag gctggcttat tggtgcagca gcaggaaaaa tagcttactg
     5581 tattggatat ggtgctctta atagaggttg tgatattagc gggaaccctt atccttggga
     5641 tggatttata tctgcgacag taagatgaat aatgtagata agattcgaaa aatacatatt
     5701 atcgtatgtt gggtgtatat atttttatca ttcagggcga ttataaatga cacggagtat
     5761 tttttgctta tttttttagc ttttatctac tcaatagtat cactacctct atattctgtg
     5821 aaaaataaaa tagtatctat ctgtctagcc ataaattcga ttctgttaat gagtttcccc
     5881 attttaatca ataagttttt cccagaaagt tttttgactt ataccgtatt aataagtgtt
     5941 tttatcctag agttagcaat ctttcattta attggggaag attttgctac taaattgact
     6001 aacgaatata agaaaattag tcagtttaga agcaaggtgt ctcaatcttc ttggataaaa
     6061 tatttagaga tttctagttt tatattaact atatttccat ctattcttta cggtacagtt
     6121 gataatcgtg tattggctct tatctttttg ataaaaattt gtgtagatac tacgataaaa
     6181 tttttattca tcagattatt tgacacaagt actttaatga agaggagaat attttttctt
     6241 ttcgcattgg atgttatagc ttacttattt ttaggatatc ttttagtgat tcaaaaagca
     6301 ggctatttgt tttcggtttt acttcttttt tctaattttt cagttccatt tatcaaagca
     6361 aaggaatacg aattatttaa aaatagcaag taatagaaac ataggttaaa tcttagaacg
     6421 gcttaaaatc agatatgata aagggaaata gtcttatcta ggtaactaag tgctacaaac
     6481 acagtcgagg atcacttgtt aggattacat tttaatcatg cttaataaga atggagaatt
     6541 cctatgggga ttgtattact ctgaagtttc gaatacctta gttctcgtga ttttgagctg
     6601 ttctagcttt agaatccttc agaatgtaaa attttaagca gtcaaagact tagaatagcc
     6661 tggaaacatt tattttatag caattctagg cttagaattg ctcatatata tgtatttgag
     6721 ctgctcgata gttaggacag ctctattctg agaaatctga gctatcaatg cttcagaata
     6781 gtatttcgca aatggttttt attgaagagg tgattgtgtt atgatagtct aaaataaaac
     6841 tgatttaatg gagtaaatgg agaatcgtca catgaaacat ttttttgcag gaattggtga
     6901 gataaaactt gttggctact tattgtatat atgtgtagga ctagcccttc tttttcatat
     6961 atatgtcata ggttcggaac tgagttttgt gaaaatagtg ttatctattt tgggagttat
     7021 atttgtaagt atgttaacta ttgctcgaat ttatcggact tttctataaa gaatagtttg
     7081 gacttgaact gtatctaaaa acagaggttg gtcgattatc agcctctttc ttgtcgttga
     7141 aaagagtgag atatattgac ttttgaaaaa aatgtcataa ttgagttggg ataaacctaa
     7201 aagtaatata gtagattgaa tctggaatag tccgttatga ctgttaaaat atttctagaa
     7261 attaatttga ctttcctaat cgatttgttc acatcttgtt tcaatctact atactttctc
     7321 gttaaaccgt tcggcaattc atggtgacat ggacacatag tagtaagcac actatgtggc
     7381 ttggcagagc taaaaactgt tcccttgcga taagcctaat aagcacaaca tagggagtta
     7441 gagaagccga ctctaatcaa ccactttggg cagtagtgag aactgccccg tgctttttta
     7501 ttttgagaaa atatggagtt tgtcgttgaa attacttgat tgtattttgg actatcaaga
     7561 aagattcaat ggaaaaacat gtcaagtatc aacgaattat aagtatttag agattttcaa
     7621 agtgaatttt tgcttgactg atttacatca tttatttgac ttatacaaaa tcacacgaga
     7681 ttatgctagt caaacaaaac ctgctattca agctggtgtt tttattttag aagattttag
     7741 aaatatccta tgtacaatga tgtaatcgaa aggatatctt tatatgagtt tatcggtgat
     7801 attttctatt ctaaaataat aagttgttgc atcgtagcta gggatttatc taaaaatact
     7861 atgaaattgg acgtcatatt ttttgaggat aaaaataaaa gatccgcagt tttaggttta
     7921 cgaagagaca aaagcggagt atttaaatca gttactctac attttacaag cgctaagaaa
     7981 tatgctaaag ttcgtaaaac agatgtgaaa gaaatgaaat ggctataaag attgtccgca
     8041 ggcttaagct tgcgtttttt gttgtttaac gaaattaaaa aacaagctct ctcatcggaa
     8101 atgtttttat aggaatgaag gaagatgatg ctatgtttaa aaagagaatc gaaaagggca
     8161 aaagtagtat ctttatctat tttttggagt agaagcttat gatatagaaa tttgtaataa
     8221 aaatgtaata taaaacattt gacaaatatt tacgggggga gtatacttaa tataagtata
     8281 gtctaaaaat gactatcaga aaagaggtaa atttagatga ataagaaaaa aatgatttta
     8341 acaagtctag ccagcgtcgc tatcttaggg gctggttttg ttgcgtctca gcctactgtt
     8401 gtaagagcag aagaagctcc cgtagctaag cagtctcaag ctgagagaga ctatgatgca
     8461 gcaatgaaaa aatctgaagc tgctaagaaa gaatacgaag aagctaagaa agatttagaa
     8521 gaagcaaaag ctgctcagaa aaaatatgaa gacgatcaaa agaaaactga agagaaagca
     8581 aagcttgttc aaaaagcgga tgaagagcgt caaaaagcga atgtggcagt tcaaaaggcg
     8641 tatttaaaac tccgagaagc acaagaacaa ttgaacaaaa gtccaaacaa taagaaaaat
     8701 gccgctcaac agaaattaaa agatgcatta gctcatattg atgaggtaac attaaaacaa
     8761 aaagaggcgg aagcgaattt caataaggaa caagcaaaag tagttcctga agcagataag
     8821 ttagctgaga ctaagaaaaa agcagaacag gctgaaaaaa aagaaccaga acttgctaaa
     8881 aaagtagcag aagctaaagc aaaagcagaa gaagctgaga aaaaagctgt tgaagccaaa
     8941 caaaaagtgg atgctgaaaa atatgctctt gaagctaaaa tcgctgagtt ggaatatgaa
     9001 gttcagggac tagaaaaaga gctcaaagag attgatgagt ctgactcaga agattatatt
     9061 aaagaaggtc tccgtgctcc tcttcaatct aaattggatg ccaaaaaagc taaactatca
     9121 aaacttgaag agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa
     9181 aaagatgtag aagatttcaa aaactcagac ggtgagcaag ctgaacaata tcttgttgca
     9241 gctaaaaaag acttagatgc taaaaaagct gaattagaaa atactgaagc tgaccttaag
     9301 aaagcagttg atgagccaga aactccagct ccggctccta aaccagcccc
//
LOCUS       DAVIME010000065         8853 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVIME010000065 DAVIME010000000
VERSION     DAVIME010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.065"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..148
                     /locus_tag="VV588_001936"
     CDS             <1..148
                     /locus_tag="VV588_001936"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084215.1"
                     /translation="LMSDGFYEFYQNNQNKTFEELIKMRFNSSAIDPIYGKKDDASIV
                     VIDV"
     gene            206..847
                     /locus_tag="VV588_001937"
     CDS             206..847
                     /locus_tag="VV588_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU7084216.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            860..2335
                     /gene="galT"
                     /locus_tag="VV588_001938"
     CDS             860..2335
                     /gene="galT"
                     /locus_tag="VV588_001938"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU7084217.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            2348..3358
                     /gene="galE"
                     /locus_tag="VV588_001939"
     CDS             2348..3358
                     /gene="galE"
                     /locus_tag="VV588_001939"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU7084218.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3538..4197
                     /locus_tag="VV588_001940"
     CDS             3538..4197
                     /locus_tag="VV588_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU7084219.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            4222..5289
                     /locus_tag="VV588_001941"
     CDS             4222..5289
                     /locus_tag="VV588_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU7084220.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELASKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALVGQKEQNVVFKVMSPEIGVPFVTEQTMILS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            5392..6402
                     /locus_tag="VV588_001942"
     CDS             5392..6402
                     /locus_tag="VV588_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084221.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            6414..8105
                     /locus_tag="VV588_001943"
     CDS             6414..8105
                     /locus_tag="VV588_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU7084222.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            8108..8818
                     /locus_tag="VV588_001944"
     CDS             8108..8818
                     /locus_tag="VV588_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU7084223.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         3029 a         1205 c         1733 g         2886 t
ORIGIN      
        1 tttaatgagc gatggctttt atgaattcta tcaaaataat caaaataaaa cttttgaaga
       61 gttaattaag atgagattta attcttctgc tattgatcca atctatggaa agaaagatga
      121 tgcaagtatt gtagttattg atgtttgata tattgtttaa aatattaatt gttactattg
      181 aactttgtta agaagaggta cctaaatgtt aaggttatat ttagaaaatg aaattataga
      241 attatcaaat aatttagaga ccatttgggt atctgtgctt gataaatatg agaagttatt
      301 tgaatattta tcaaatgaag aacgaataga attgattaaa gaagatttaa tcataaatga
      361 gtcagttcta aatgttgata aaaaaggata tgagttaatt tgtttacaac atcccgtttc
      421 atatgactta agaagaatta ttagtgtaat aaaaatatca actgacattg aacgtattgg
      481 ggatagaatt gttgaaattt taaaaaatct acagattatt caaaataatg aaattttgaa
      541 gaaaattatt tcagaaataa aaatacttca tgaagttatc ggactgcata tgaatagggc
      601 tatatcttgt tatagagagg aacaatctgg atgtttagat atggttgtta tacaaaaaca
      661 gaatgagata gaagagctta gtacaaatat tgaaaagaaa ataatgaatt acatatttga
      721 agatgatggg aatgtttctg aagtaattgg tgctttagat attattcatc accttgataa
      781 aattgctcat actacgcaat caatttataa atggataatg tatagaaaat atgggaacat
      841 aaattagaaa gaaaaatata tgaaaacaat tattgataat tttgttgata gagtaattga
      901 atacggaatg tataatgaaa ttgacaaaat atatgtgaaa aatagagtac tagcgttaat
      961 aggtgaggag ggaactgatc gcatttccga tgaaaatgac ctgaaacaaa taaaagatta
     1021 cttagtggaa atcgccttaa aaaacggtaa aattaaagat ttaatcgagg aaaaggaatg
     1081 tttaggagca gagttaatga atttcatagt tcctttacct agtcgattaa atgatatttt
     1141 ttggagttca tatgatatat cacctcaaga agcagttgaa gagttttata agttaagtaa
     1201 agatagtgat tatattaaaa cttctgctat tgctaagaat attgagtttc gagcatcaac
     1261 taaatacgga gagctagaga ttacgataaa tttgtcaaaa cccgaaaaag atccaaaaac
     1321 aattgctgct gaaaaattag taaaagccac taattatccc aaatgtttac tatgtatgga
     1381 aaatgaagga tatcaggggc gaataaatta tccagcacgt tcgaatcata gaattattcg
     1441 attgaaactt ggtgacgaag tatggggatt ccaatattct ccctacttat actttaatga
     1501 gcatgcgata tttttaaata gtcaacatgt accaatggct attacctcta aaacatttga
     1561 acaattattg gagattgttg atattttgcc aggatatttt gctggttcaa attctgatct
     1621 tcctatctca ggaggctcca ttcttagtca taaccactac cagggaggga aacatatttt
     1681 cccaatggaa aaagcaaaat ttgagagtga atttcgtttt aaagactttg aggatgttaa
     1741 tgctggtatt gtaaaatggc caatgtcagt aattaggtta caaagtgaaa ataaaaatcg
     1801 cttgttagat ttagctacta aaattctaaa taagtggaga gaatattcag atttagaagt
     1861 agacatcatt gctatgactg aagatgtccc acaccatacg gtgactccta ttgctcgtaa
     1921 agtggacggg agatatgaat tagatattgt tctaagagat aatcatacta ctgaacagta
     1981 cccagatggt gttttccatc ctcatcaaga tgtacaacat attaaaaagg aaaatatcgg
     2041 gttaatcgaa gtgatgggac ttgcgatatt accacctcgt ttgaaaccag agttagaaga
     2101 agttggaaaa tatcttttag gagaggataa cgcaattgcg gattatcatt tagaatgggc
     2161 cgaccaattg aaagaaaaat atcctcgcat taataaagaa gaggttaata gcgtagttca
     2221 acacgaagca ggacaagtgt ttgcgagagt tctggaagat gcaggagttt ataagaatac
     2281 accgtctggg catgaagcgt ttatgagatt tgttaagtcg gttggaatta attaggagga
     2341 aacaaaaatg gcaatattgg taacaggcgg agctggttat attggtagcc ataccgtagt
     2401 agaattacta aatttaggaa aggaagtcat cattgtcgac aacctttcga actctagcat
     2461 cttggtgcta gaccgtattg aagcaattac aggaatacgt cccgtgtttt acgaattaga
     2521 tgtttgtgat aaaccagcat tgagaaaggt atttgaacaa gaatcgattg atgctgcaat
     2581 tcattttgca ggttataaag ctgtcggaga atccgtgcaa aagcctgtga tgtactacaa
     2641 aaataatatt atgagtacat tggcacttgt tgaagtgatg tcagaattta atgttaaaaa
     2701 gattgtcttt tcttcaagtg cgactgtata tggaattaac aatcagtcac ctctaattga
     2761 gactatgcaa acaagtgcga caaatcctta tgggtatacg aaagtgatgc ttgagcaaat
     2821 tttaaaagat gttcatgtgg cagattcaga atggagtatt gcgttgcttc gttatttcaa
     2881 tccaattggt gctcatgagt ctggtttgat tggggaagat ccctcaggaa ttcctaacaa
     2941 cttgatgccc tatattgcac aagtagcggt aggtaagctg tcagaactaa gtgtgttcgg
     3001 aaatgattat gatacgcttg acggtactgg tgtgcgcgat tatatccatg tagtagattt
     3061 agcaatagga catataaaag ctttagaaaa agtatctgaa aaaacagatg tttatatcta
     3121 taacctaggc tcgggagaag gcactagtgt attacaactt gtaaatacat ttgaaagtgt
     3181 taataagatc cctattcctt ataaaatagt tccaagacgt tcaggagacg ttgcaacttg
     3241 ttatgcaaat gcagacaaag catataagga attaaattgg aggacaacaa aatcgattga
     3301 agacatgtgt agagatacat ggaattggca atcaaaaaat cccaatggct ataattgatg
     3361 atactgtcta tatgagtgct gtattttgga aaaattactt aaccttttaa tgaaatgcat
     3421 atttaatgaa agataaattt aaaaaaatgt ttgcaagtgc ttgacaaagg aaacggtttc
     3481 attgtataat gtaaacatgg tgacaccgat gtcaaatata aaaaagaagg tctttatatg
     3541 aaaaacttaa caaaaattaa gttcaaagag aatggggaat ttaatcattt ccctgggaat
     3601 acagttgtag caaatcttta tactaaacaa gatttgatgg aagttgttga tattattcaa
     3661 tcacgttata gagaattacc atttatcgat aagtttactt taactccaag gaattctatt
     3721 cacatgactg taattgaatt gttgtgccat gaaaatcgtg aaacggagtt ttggagcagt
     3781 aatcttcctc tagatacacc tttacaggaa atacatgatt actttgctaa acaacttgaa
     3841 atttttccat tgttggatga agaaattcat atgcgtataa ctgaaatggg aaaacaaaac
     3901 atactagttg aacctgcaga tgaagcttct gcaaagagat tagaagaaat tcgtacttat
     3961 gtctcagaaa aagcaggtgt ttgtttccct aatcatgata gatatcaatt ccatatttca
     4021 attgggtatc ttcggattcc tctaaccgaa gaggaggaag aagagtttac taaagtcaga
     4081 gcagaattaa ctgaaatttt attagagaag attccaacta ttactgtaaa ccgtattgac
     4141 tatactgtat ttgaagatat gagacaattt gttccatatc acgaaaaatt taaataaaat
     4201 aataaaaaag gagaacttat catgaaaaaa atgaaagttt ggtctactgt acttgcaacg
     4261 ggagttgctc ttactacact tgctgcttgc tctggaggtt caaattctac gactgcttct
     4321 tcatctgaag aaaaagctga taaaagtcaa gaattagtta tctattcgaa ctcagtctca
     4381 aatggtcgtg gtgattggtt aactgctaaa gcaaaagaag ctggttttaa tataaaaatg
     4441 gttgatatcg ctggcgctca attagcagac cgtgttattg ctgagaagaa taatgcagtt
     4501 gcagatatgg tatttggaat tggtgctgtt gactcaaata aaattagaga tcaaaaatta
     4561 ctcgtacagt acaagcctaa atggttagat aaaattgatc aatctttatc agataaagat
     4621 aattattata atcctgtgat tgttcaacca ttagttttaa ttggggcgcc tgatgtaaaa
     4681 gaaatgccta aagactggac agagttagct agtaagtata aaggtaaata ttcaatttat
     4741 ggtcttcaag gtggtacagg acgggcaatt ctagcaagta tcttagttcg ttaccttgat
     4801 gaaaaaggag atttaggcgt atcagaaaaa ggatgggaag ttgcaaaaga atactttgca
     4861 aatgcctata ctcttcaaaa aggtgaaagc tcagttgtta aagcgttaga taaagaaagc
     4921 ccaattcaat acggtatgat ctgggggtcc ggggctctag ttggtcaaaa agaacaaaat
     4981 gttgttttta aagtgatgtc tcctgaaatt ggggttccat ttgtaactga gcaaacaatg
     5041 attttgagta caagtaagaa gcaagcattg gctaaagaat ttattgattg gtttggtcaa
     5101 tctgaaattc aagtagagta cagtaaaaac tttggctcta tccctgccaa taaagatgcc
     5161 ctcaaagagc taccagaaga tactaagaaa tttgttgatc aagtgaaacc acaaaatatt
     5221 gactgggaag ctgttggaaa gcatttggat gaatgggtag aaaaagctga attagaatac
     5281 gtacaataag aaataagagt tattttttat gtccaagtct ctctattatt tctaaattta
     5341 aggaagaaat aaagagaggc ttttggttta gtaatagagg gagttagtga gatgattaaa
     5401 tttgataata ttcaaattaa atatggtgat tttgttgcaa ttgataatct gaatttagat
     5461 atacatgaag gggaattctt tacatttctt gggccttcag gatgtggtaa atcaactact
     5521 ttgagagcat tggtaggttt tttagatcca tcatcaggaa gtattgaagt taatggaaca
     5581 gatgtcactc atttggaacc tgaaaagcgt ggaattggta ttgtatttca atcttatgcg
     5641 ctatttccaa ctatgactgt ttttgataat attgcatttg gtttaaaagt taagaaggta
     5701 gctccagatg ttattaaagc taaagtatca gcagtggcag caaaaattaa gatctctgat
     5761 caacagttac agcgtaatgt atcagaatta tctgggggtc aacaacaaag ggtagcattg
     5821 gctcgtgctc tggttcttga acctaaaatt ctttgtctag atgaaccatt gtcaaacctt
     5881 gacgcaaaat tacgtgtaga tttgagaaaa gagttgaaaa gacttcaaaa agagttaggt
     5941 attactactt tatatgttac tcatgatcaa gaggaagcct tgactttatc tgatagaatt
     6001 gcagtcttta acaatggata catcgaacag gtcggtacac cagtagagat ttatcataat
     6061 tctcaaactg aatttgtatg tgattttatt ggagatatta atgttttgac cgatgaaaca
     6121 gtccacgaag tattattgaa aaatacaagc gttttcttag aggataaaaa aggatacatt
     6181 cgattagaga aagttcgatt caatcgtgaa actgaacaag attttattct aaaagggaca
     6241 attattgatg ttgagttttc tggagttaca attcactata caataaaagt ttctgaaagt
     6301 cagattctta atgtaacaag tattgatagt caggctgcta ttagatctgt cggagaaagt
     6361 gtggaattat ttatcacacc atcagacgtt ctgcaatttt aaggaggtgc agtatgcgtc
     6421 ataaattaaa tttaaaagat tggcttattc gtttagggtt aatctggttc ttagtaacat
     6481 ttattattta tccaaacttt gatctagtag tgaatgtatt tgtaaaagga ggagaatttt
     6541 cccttgatgc tgtacatcgt gttctaaaat ctcagagggc acttcagagt attatgaaca
     6601 gttttaagtt agcattttca cttattatta cagttaatgt cgtaggtatt ctttgtgttc
     6661 tatttacaga gtactttgat attaaaggtg ctaaaatttt aaaattaggt tatatgacct
     6721 ctttaattta tggaggagtg gttttagcga ctggatataa atttgtctat ggtccttatg
     6781 gattgattac aaaattttta caaaatgtta tcccttcttt agaccctaac tggtttattg
     6841 ggtatggtgc agtcttattc attatgacat tttcaggaac tgctaatcat acattgtttt
     6901 taacaaatac aattcgaagc gttgactatc acactattga ggctgctcga aatatgggag
     6961 caaaaccatt tactgttttc cgaaaagtag tgttaccaac cttaattcca actctatttg
     7021 cacttactat tatggttttt cttagtggtt tatctgcagt agcagcaccc atgattgttg
     7081 gtggtaaaga atttcaaact ataaatccaa tgattattac atttgcaggg atggggaatt
     7141 ctcgtgattt agctgcctta cttgcaatta ttttaggtat tgcaactaca attttgctta
     7201 ctatcatgaa taagatagaa aaaggtggaa attatatttc tatctctaag actaaagcgc
     7261 ctcttaaaaa acaaaaaatt gcgtctaagc cttggaatat cattgctcac attgtagcat
     7321 atggattgtt cacagttttc atgcttccac taatttttat agtattatac tcatttacag
     7381 atccagttgc aattcaaaca ggtaacttaa cattatcaaa ctttacttta gaaaattatc
     7441 gcttattctt tagtaatagt gcggcattct ctccattctt ggtcagcttt atttattcta
     7501 ttattgctgc gacaacagca acaattctcg cagttgtatt tgctcgtgtt gtcagaaaac
     7561 ataaatctcg ttttgatttc ttatttgaat atggtgctct acttccttgg ttactaccaa
     7621 gtacactttt agcagtaagt ttattattta cttttaatca gccacaattt cttgtcttga
     7681 atcagatttt ggtaggtagt ttggtaattc tacttattgc atatatagtt gtaaaaatcc
     7741 cattttctta tagaatggta cgtgctattt tatttagtgt tgatgatgag atggaagatg
     7801 cagcaagaag tatgggtgct tcaccttttt atactatgat gaaggttatc attccattta
     7861 ttttaccggt tgttctctct gttattgctt taaactttaa ctctttatta actgacttcg
     7921 acttatctgt attcctttac catcccctag ctcaaccatt aggtattacg attcgatctg
     7981 caggtgatga aacagcaaca tctaatgcac aagctctggt atttgtttat acaattgttc
     8041 tgatgattat ttctggaacg gtattatact tcacacaaag accggggcgt aaagtaagga
     8101 aataatcatg acagccacta gtcttgggtt atcaaatatt gaaatagttg tcaggattgt
     8161 tttatcagta gtcattggta gtataattgg tttagagaga gggagcaaat cccagcctgc
     8221 aggcatccga acttatagta ttgtttgtct agctgcatgt ttgattatga tgacgaatga
     8281 atacgtatct tataaatttg ggacaggaga tcctacacga ttaggagctc aagttatatc
     8341 aggtgtgggt tttctaggcg ctggaacgat tcttattaca gataaaaaga aaattacagg
     8401 tttgacaact gcagcaggca tttgggcttc ggcaggaatt ggattagcta ttggagtagg
     8461 tttttatgag ggagctcttt tagtagccat ttctgtttgg ggtgtgatat ccatgttcca
     8521 accactaaaa aaatatctgc aaaatcgttc taaaatgatt gaattgtata tagtagttaa
     8581 atctacagaa gcctataatc gtgtattggt ttattgtgca gaaaatggta tcagaatgac
     8641 cgattcaaga acagcgtttg gagatgttaa ttctgacaga attgaatact ttgatgttcc
     8701 ggacaaaaaa atagcgtcat ttattactct ggaattatca ggtagatttg aacatcttcg
     8761 actgatggaa gaaattgcta atattgtagg tgttatttat gtcgaagaaa ttagctgaaa
     8821 tttagtaaac aaagggacag atgtttttgt cct
//
LOCUS       DAVIME010000066         8769 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVIME010000066 DAVIME010000000
VERSION     DAVIME010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8769
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.066"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            53..739
                     /locus_tag="VV588_001945"
     CDS             53..739
                     /locus_tag="VV588_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU7084224.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            740..1672
                     /locus_tag="VV588_001946"
     CDS             740..1672
                     /locus_tag="VV588_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU7084225.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1683..2612
                     /locus_tag="VV588_001947"
     CDS             1683..2612
                     /locus_tag="VV588_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU7084226.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2626..4065
                     /locus_tag="VV588_001948"
     CDS             2626..4065
                     /locus_tag="VV588_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084227.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4134..5711
                     /locus_tag="VV588_001949"
     CDS             4134..5711
                     /locus_tag="VV588_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU7084228.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPKINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5771..7231
                     /locus_tag="VV588_001950"
     CDS             5771..7231
                     /locus_tag="VV588_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU7084229.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNIEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            7253..7708
                     /locus_tag="VV588_001951"
     CDS             7253..7708
                     /locus_tag="VV588_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HEU7084230.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            7795..8201
                     /gene="cdd"
                     /locus_tag="VV588_001952"
                     /pseudo
     CDS             7795..8201
                     /gene="cdd"
                     /locus_tag="VV588_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            8214..8663
                     /locus_tag="VV588_001953"
     CDS             8214..8663
                     /locus_tag="VV588_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU7084231.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHKTGLLVEEPLNIKKVVFKVKI"
BASE COUNT         3053 a         1135 c         1651 g         2930 t
ORIGIN      
        1 tagtagatgt tattgaatta gtaaaaaaaa taaaaaaacg gaggttttct gaatggaaac
       61 taaaaaaatt aaaaatttaa aaggtcaaat aattgtttcc tgccaagcgt tagaaggaga
      121 gccactttat actccaaatg gaggagtgat gccgttatta gcaaaagccg cctttcaagc
      181 aggcgctaaa ggtattcgtg ctaattctgt ccgcgatatt tcagaaataa aagaagaagt
      241 tgacttacca attataggta tcataaaaag agattacgat ggctttgaac cttttatttc
      301 agcaactatg aaagagattg atgaattagt tagtgaagga gtagacattt tagctttgga
      361 ttgtactaat cgttcaagac caggttatga taatattact gactttattc atgatattaa
      421 agtcaagtat ccaaaccaat tattaatggc tgatatttct acttttgaag aagggaaagt
      481 agctgctgaa tcgggagtag attttgtggg tacgacatta tctggttata caccatatag
      541 ccctaaaaaa gataatcctg attttgagtt agttgaaaga ttggtaaaag agcttgacgt
      601 accagttatt gctgaaggaa gaataagtac tccggaacaa gctagaaaaa tgttagattt
      661 aggtgcttac gcagtggttg ttggaggagc tatcactcgt cctttggaaa tagcgaagaa
      721 gtttattgag gtagtttaga tgaatcaaga aatattaaaa aagagtaaga ttcaattgac
      781 agttgaacat attcaaaaat attggatttt atatttaatg atgattccag caactgttct
      841 actaatttta tttacgtatg gaccaatgta cggcattatt atggcctttc aagactttac
      901 tgtcttcaag ggatatactg gaagtccatt tgtcggttta aaacattttc aaagattgtt
      961 ctcagatcct ttgttttata gattgttcaa gaatacgttc atggtagggg ttttagactt
     1021 tttattctct ttcccagctc cgcttatttt tgcactcata ttaaacgaag tcagaaaagt
     1081 aagatttaag agtgtagttc aatctattag ttatcttcct cattttattc ccctagtggt
     1141 tatggttggt attatttttg aactatttgg ttcatatggt attattaaca gtttactttc
     1201 atcacttgga atggagccaa taagtttctt tacaaaatct gaatggttct tgcctctcta
     1261 cattggttca ggagtatgga aaacaatagg ttggggttct atcatttata tgggagcatt
     1321 aaccaatata gattcaactt tatatgaagc agcagatatg gacggggcta atagatggca
     1381 caaaatgtgg catgtaactc taccaagttt aagacctaca gtagttactt tgtttatact
     1441 aaatgctggt ggtatcatgc aagtaggatt tgaaaaggta ttcttgatgt ctagtcctgc
     1501 aacatatgaa gtatctgatg tattatctac ttatgtttat agacaaggta ttttaaattc
     1561 tgatttcagt tactcagctg cagtaggatt atttaataac atagtagctt tgttatttgt
     1621 tttattagct aataagattg ctaaaaaact tggcgaagaa ggaattgtat aaggggggta
     1681 aaatgatttt ttcaaaaaat acaaaaaaga gtaatagaga caaagaaacc ttcgttgatt
     1741 atctctttat attcatttta ataataataa ccttacttat gttgtatcca ttatggtggg
     1801 tagtgatgac gtcactttca gaaccagttt ggctatctaa aaacgttgtt aaattatttc
     1861 ccttaaaaat agatattact gcatataagt ttatttttgg ggattctaaa ctatggcaag
     1921 catatggtaa tagtgtattg tatgctgcac tatctacaat tgttagtgtt gcggtatgta
     1981 gtatgtatgc ctatccactt acaattcctg aaattagggg taaaaaattc tggaatactc
     2041 ttattttgat tccaatgttc tttagtggag gaatgatccc gctttatata caagttgcaa
     2101 acctcggttt attgaatact gcttgggctc ttgttttacc tggtgctgtt tctacatatt
     2161 atataatttt gtttagaaca cagtttaaat caatcccaat ggagcttcgt gagtctgcta
     2221 gaattgatgg ggcaagtgaa tttagaattt tttggaattt agtattacca ttatcaaaag
     2281 ttattttcat gattatagca ctttattgca tagttggttc atggaatagt tttactcctc
     2341 cattacttta tttgaatgac gacactaaga tgcctttatc tatttatttg agaaatttag
     2401 ttgttacaaa tacaactgat actgctgaat tatcactttc tgcaggtaat acatattacc
     2461 aacaaattgc tgctcaaggt ggaggtattg gtatgcgtat tgctattaag atgggtacta
     2521 ttgttgttag tgttattcca attatgatga tttatccatt tattcagaaa cattttgtta
     2581 agggaatcct gctaggttct gtgaaaggtt aataaggtaa ttattttgca aaatttaaaa
     2641 aaatatcttt tattagatag cggtttagta gttgggtata cattagaaaa tgctcaatta
     2701 aaattaaata agctaaaaaa agatactgaa aacaatccac tatttggtga agagtatttt
     2761 gccgaaaatc ctaaattatg ggaagttcgt tttgataatt catatccaaa cgttatctat
     2821 gataaagaat tgaaattata tagatgttgg tatcaaacat ttgttagtga tgaagcaagc
     2881 gaagagactc ctttagcaga acgtggagag aaggaataca ttgtcaagtc atctagaatg
     2941 acagcacttt gctatgctga aagtaaagat ggagtaaaat gggaaaaacc aaatctcaat
     3001 ctagtaaaat ttaaaggttc aaaagataat aatattgttc tgatgcatgc acacggtgca
     3061 ggtatcatgc tagatgaaca ggagttggat cctaagaaac gatataaatt agtttcaaaa
     3121 ttagaatttt ctccgaatct tcattacatg gttgttgttt tttcagaaga cggtattcat
     3181 tttgacgaac ctattccatg gaaaaaatgg aatcctgcag cagatagtca taattttcca
     3241 tttagagatc caaaaactgg taaatacgct gttattacaa gaacctgggc aaataacgta
     3301 cgtctaagtg caattacttt cagtgatgat tttattaatt ggtcagaacc taaagaaatc
     3361 cttaggggag atggatttga agatcaaatt tattctatgc cagtaatttc atacgcggat
     3421 atctatttag gttttgcttc aatgtaccac gaaggcgaca ctttaaatga aaactatgat
     3481 aaagtagact tagaattgaa attctctgct aatttggaac aatgggatag tgtatgtaag
     3541 ggcgactatc tcattgaaag gggaggtgga gtatacccgc agaatgctga ttttgatgct
     3601 agttgtattt tcacggctgc tccaataatt gaagatgata agatttggtt ctactatatg
     3661 ggtggaaatg gtaatcacac tggcttccga gaaagttcat tagctagagg atatattaag
     3721 aaagaccaat ttgcttatta tactaataag agagaaggaa ttccagctaa aatatctaca
     3781 gttagcttcc aaacttacga tgatgaaatt tatatcttag ctgatattcc tgaaaatggt
     3841 tatattaaag ttgcggtagg tactaaatac ggtaatgctt attcagattt tggtcaggaa
     3901 gatatctctc ttgttcaagt ttccgatggt aagtataagt tggaatttaa taaaaaatct
     3961 atcttagatt taggtaattc tccagttgcg ttcaaatttg aaatcgagaa tgcaaaattg
     4021 tatggtattg aaggtagtat tcagcaacac tatctcaaat attaaccaga ataattcgtt
     4081 aacaaataat ctctatatta gtggagatag atatataaaa tggaggtctt attatggtaa
     4141 agcttaataa ggtattaaaa gggagtgttg cattcctgag tgcaagttta ttgctagcag
     4201 cttgtggcaa taacgctaat tcaaagcccg ctgaaaaaac agctgatggt aaaacgaaaa
     4261 tttcgtttct atctacatgg caaattaatg atgttcgtcc gcctaaagat gaaacacttg
     4321 ttggtcaatg gttagaagaa cagctaggta ttgatattga tcttgtaact attcctggcg
     4381 agggagtaag ttctaaagta aattctctta ttactagtaa ccagttaccg actgttttgt
     4441 tgacaacagg agataagagt gatatcgctg gtatcaacaa acttggtaaa cagggtgcat
     4501 tcttagattt gtcacaacac atggacaaac taccaaacta taagaagtac cttgaaaaaa
     4561 ataatgcatt agctcaaata gaagatgatg aaaaacatat ttatgctttc acaaaattct
     4621 ttactgatga gaatatcatg tatactacac caattctgag aaaagactta cttgttggtt
     4681 cagaatttga agatctttca aaaattaaaa ctgttgatga ctatacaaaa gttttgaaat
     4741 atttgactga aaaacaaggt tctccagcat ttattcaacg taatggctat gaaggcttca
     4801 tgaagcgagt tacaccattg tggaatttaa gccatcgtac atactatgac tatgaatcag
     4861 attcatataa acatccagtt gaacaacctc aattgaaaca attcgttgaa tggttgaaag
     4921 aattacgtaa agataacgta cttcaccctg actgggcagt tatgaaagat gaaacttggg
     4981 aaggtctatt ggcttctaac aagggttcat tcactgttga ccgtatgaat atcattggag
     5041 ataataactt tgataaatca tttgattggc agccacttgt ttatccaaaa attaatggaa
     5101 aacgttattt gcaaccgaaa acaccgtaca tttctgattc aggttgggta atcaatgcca
     5161 atgcaccaaa agaagaaatt gataaagcgt tagaattctt taatttctta tacgctgatg
     5221 aaaatcaaga aaaacttgct attggatttg aaggtaaaac atttacacgt gaaaacccta
     5281 atactcaagc aggtattaaa tggttgattc aaatttacgg tgaaaatgct ggaaatgata
     5341 aagcagaact gctgtttaaa catggtaacc aagcatttac tcgcgttcaa actaaattag
     5401 atattgaggc acagccagga acattcccta aagttatgta tgatcaagta gataaaatta
     5461 agaaagattt aggtggtttt agaccagata ctccggttct ttcctttaca actgaagaat
     5521 tagatgtttt aactaaatct gaagcaggat taaatacttt ctttgatgaa aatattatta
     5581 aattcattga aggacaaaga gatatgagtg agtgggattc atttatcaat gaagctaaat
     5641 ctaaagactt ggataaagtt acaaaagtat ataatgatgc ctacaaacgt gtcaaagata
     5701 gaatgaaata gactaaatgg tagctctctg gtttttcaga gagctactac tgcctgaggg
     5761 ggagtaagct ttgtatgatg tagtaattat aggtgcagga agttcgggcg cattggctgc
     5821 aattgcttcg gggcgtctag ggttaaaaac ttgtctaata gagaagggaa gtagaattgg
     5881 tggagttcct attaatacac taatggggtc atttgctaat ctatattttg atgattctgg
     5941 tagagtaaat gcaagtaaaa ttgttgggga attaatagaa cgtattatca aaaaaggtgg
     6001 tactgtcttt aactctatgg aagaattgat gaatgtaaat gatttttatc agattacaat
     6061 tccctatcaa ccagaagttt atgaatcggt tttaactgat atgttgattg agtctaaagt
     6121 tgatatttta ctaaatattg aagttaataa tattatttat gatagtaaaa atattaaaag
     6181 tcttgaaatt ttaagtaatc aggaagttaa attgattgat tctaaagttt ttattgatgc
     6241 tacagggaat gcaacaattg cttctgctag tggagctgat gtttatgaaa aaaattcttc
     6301 ttacggttgt ttaatgagag ttggaggagt tgatatctca aagactatag aacatattga
     6361 aaaaacaaag cagtggaact atatagaagg atataatcag tggttagaag aagtattagc
     6421 aaatcgaaag tacagagcca ctggagcagt tttaaaagat ccagtttctt atgatcatgc
     6481 ccctatgctt tcaaaagacg accattttat gaatgatgaa aaatggaatt acattaaaga
     6541 aagatgggaa aaatttagat ttatttacac tttagaagta tcactattta ggaatgaatt
     6601 aaaaaaagct gtagaatctg gggattttaa ttttgaaatt tatcatgatg ataaatctgg
     6661 agtcactatg aatggcgacg gtataagcta tggttcatgg ggtcaaaatg tagcattaat
     6721 taatgttgca aaagcatttg gattcaatcc caaatatatg gaagatgaat cacatgctaa
     6781 tattctttct agaaaatata atttaacatt tttatctttt cttaaaaaat atgtaccagg
     6841 ttttgaaaat tcttttatcc ttgatcaggg aactagagct actaacagat catgtaggca
     6901 cattgataat tcatctatga tggacgaaat tcttgatttt ccaatgtata catttaagac
     6961 tatgtatagc tatcaaactc ctaaagaaat aacgtacaaa tcaattgtag gtggaaaatt
     7021 gaataatttg tttgtaatag gtaaaggtgc ttaccaatcc gaaagtttta gatcacaaat
     7081 tagttgtatg ttaatgggga tatcatcagc agcagcggca aaaactatta ttgaagataa
     7141 aagcaatact ctaaacatta atagagattt gtttaaatcg aacttagata tattatttac
     7201 atgggagttt tctaattgga ttactgatta acaaataata agggaatatt aaatgaatga
     7261 tactaataaa aatcaatact ttgtttatga atttgatact agctttgtag aaatgtctta
     7321 ttctcagttt tttgaaggat attgtattct tttttcaaaa gaaccctatc cttctttatc
     7381 tgatatgcca atggaattta gaaaagaatt tttaatggaa atgagtatat taggtgatgc
     7441 gatgcttgaa gtgttaaatg cctatagaat taattatgat atcttaggaa attcaacacc
     7501 tgtacttcat gctcatttat ttccgagata catgtgggaa gaggaagaga gaagaaaaac
     7561 tgtagttcat agatatgatt cttcagtttt tagcaatcct gagtttgaat ttactataga
     7621 aaagcatgga ccaattatta aaaaactgag gtctgctatt gatagacatt atagagagta
     7681 tcaacaatta ttagatgatt caaactgaac tccacatttt cgattagatt taataccttg
     7741 tatattacaa ctaggttgtg gatgatataa ttttttgaaa aatatatttt aggaatgact
     7801 tataaagcaa ttatatcaga ggctattaaa tcaatggcca aagcttatgc tccttattct
     7861 gattttaagg ttggagctgc gttagtaact gaagataaaa aattttttct ggatgtaata
     7921 tagaaaatgc tgctttttct cctacttgct gtgcagaacg agtatctttt tataaagctg
     7981 tatttaaagg agaacgttcg ttttcaagaa tatgtattgt aggtggaaaa aatggtatct
     8041 tatcatcttt tatagcacct tgcggagtgt gtcgccaggt aatgatagaa ttttgtaatt
     8101 ctgattcatt tgaagttata ttggctagtg atgttgatac ttataaagta tataaactta
     8161 aagaactact accagttagt tttaatcaag aaaatttata acaggaggga actatggaat
     8221 tagttgaatt taaaaatgga catgttaata cggttcatga gcatatcgca ataacgaaag
     8281 taaaagagtt tctaaataat catgatatac caaaagataa aggtggcata cataaaattt
     8341 ctactgattt cttttacaat ataattgata tggaaactac aactgaagag aatagaccgt
     8401 gggaaagtca taaggaatat tatgatgtcc attatctgtt aaatggagaa gaaataattt
     8461 tatataattt cttgtctcaa atggaattgt ctgaatataa agtagatgat gattggcaac
     8521 aaatgaatgg gacagcttta tttagtatta aattaaagaa agatatgtta cttttgttgg
     8581 aaccaaacga tgcacataaa acaggcctat tggttgaaga accacttaat attaagaaag
     8641 ttgtttttaa ggtaaaaatt taactgaaag tactttcggg gattaagaat tttaaaatat
     8701 ttaagaaatt gtattctaaa gttctaaaat tatagatatt taatttaaag cttgttaaaa
     8761 tagaatagt
//
LOCUS       DAVIME010000067         8532 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVIME010000067 DAVIME010000000
VERSION     DAVIME010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.067"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            165..2798
                     /gene="polA"
                     /locus_tag="VV588_001954"
     CDS             165..2798
                     /gene="polA"
                     /locus_tag="VV588_001954"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU7084232.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNMSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDQLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2883..3320
                     /locus_tag="VV588_001955"
     CDS             2883..3320
                     /locus_tag="VV588_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU7084233.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(3505..4515)
                     /locus_tag="VV588_001956"
     CDS             complement(3505..4515)
                     /locus_tag="VV588_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU7084234.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVINAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            4664..5833
                     /locus_tag="VV588_001957"
     CDS             4664..5833
                     /locus_tag="VV588_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU7084235.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLKDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5830..6600
                     /gene="recO"
                     /locus_tag="VV588_001958"
     CDS             5830..6600
                     /gene="recO"
                     /locus_tag="VV588_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU7084236.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            6597..7589
                     /gene="plsX"
                     /locus_tag="VV588_001959"
     CDS             6597..7589
                     /gene="plsX"
                     /locus_tag="VV588_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU7084237.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            7595..7828
                     /locus_tag="VV588_001960"
     CDS             7595..7828
                     /locus_tag="VV588_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU7084238.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            7874..8164
                     /locus_tag="VV588_001961"
                     /pseudo
     CDS             7874..8164
                     /locus_tag="VV588_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            8367..>8532
                     /gene="blpU"
                     /locus_tag="VV588_001962"
     CDS             8367..>8532
                     /gene="blpU"
                     /locus_tag="VV588_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU7084239.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTRTWQGA"
BASE COUNT         2476 a         1544 c         2150 g         2362 t
ORIGIN      
        1 caaggtgtac tattatagat tcaatatact atattatagc acatttttaa atctaggttt
       61 actaaattct ctggctctat ctatttattc ggaaaaagtt tgaaaaatac ttgctctagc
      121 tcttcccaat ggtatttttt gattctttcc tttataatgg gtgtatggat aagaaaaaat
      181 tattattgat tgatgggtct tctgtagctt ttcgggcgtt ttttgcgctg tatcagcagt
      241 tggaccgttt taagaatgcg gctggtttgc ataccaatgc gatttatggt tttcagttga
      301 tgttgagtca tttgttggag cgggttgagc cgagtcatat tttggtggct tttgatgcgg
      361 gaaagacgac cttccggaca gagatgtatg cggactataa gggtggtcgg gccaagactc
      421 ctgatgagtt tcgtgagcaa tttcctttca ttcgtgagtt gctggatcat atggggattc
      481 gtcactatga gctggctcag tatgaggcgg atgacatcat tgggacgctg gataagctag
      541 cagagcagga tggttttgat attaccattg tcagtgggga caaggatttg attcagctga
      601 cggatgagca tacggtggtt gaaatttcca agaaaggtgt ggctgagttt gaggccttta
      661 cgccagatta cctcatggaa gaaatgggcc tcacaccagc tcagtttatc gatctcaagg
      721 cgctcatggg tgataagtcg gataatatcc ctggggtgac caaagtcggt gaaaagacgg
      781 gtattaagct cttgctggag catggttcgc ttgaggggat ttatgaaaat attgatggaa
      841 tgaagacttc taagatgaag gaaaatctca tcaatgacaa ggaacaggcc tttttgtcta
      901 aaacactagc gaccattgat accaaggcac cgattgcgat tggtttagag gacttggtct
      961 atagtggtcc agatgttgaa aatcttggga aattctacga tgagatgggc ttcaaacagc
     1021 tcaagcaggc tttaaatatg tcgtcagctg atgtggctga gggtttggat tttactattg
     1081 ttgaccaaat cagtcaagat atgctgagtg aagagtctat cttccacttt gagctttttg
     1141 gtgagaatta ccatacagat aatttggttg gatttgcctg gtcttgtggg gatcagctct
     1201 atgccacaga caagcttgag ctgttgcaag acccgatttt caaggatttc ttagaaaaaa
     1261 catctctgag agtttatgac tttaagaagg ttaaagttct tttgcaacgt tttggtgtag
     1321 atttgcaggc gcctgctttt gacatccgtt tggctaaata cctcctttcg actgtggagg
     1381 acaatgaaat tgcgaccatc gctagtcttt atggtcagac ttacttggtt gatgatgaaa
     1441 ctttctacgg taagggtgtt aaaaaggcca ttcctgaacg tgagaaattc ttggaacact
     1501 tagcttgtaa acttgctgtt ttggtagaaa cagagcctat tttacttgaa aaacttagcg
     1561 aaaatgggca attagagctt ctttatgata tggagcaacc tctggctttt gtccttgcca
     1621 agatggaaat tgctgggatt gtggtcaaga aagagacctt gcttgagatg caggctgaaa
     1681 atgagcttgt cattgaaaaa ctgactcaag agatttacga gctggctggt gaggagttta
     1741 atgtcaactc gcctaagcag ttgggcgtgc ttctctttga gaaattggga cttcctctag
     1801 aatacactaa gaaaaccaag acaggttatt cgacagcagt ggatgtgttg gagcgtctcg
     1861 ctcctattgc tccgattgtt aagaaaatcc tggattaccg tcaaattgct aagattcaat
     1921 ctacttatgt aattggcttg caggactgga ttttggctga tggaaagatt catactcgct
     1981 atatgcagga tttgacccag accgggcgtt tgtctagtgt ggatccaaac ttgcaaaata
     2041 ttcctgcccg attggaacaa gggcgcttga ttcggaaggc ttttgtgcca gagtgggagg
     2101 atagtgtgct actcagctct gactattcac agattgaatt gcgcgttttg gcgcatattt
     2161 ctaaggatga gcacttgatt aaggccttcc aagagggggc agatatccat acttcgacag
     2221 ccatgcgggt ctttggcatt gagcgtcctg ataatgtgac tgcaaatgac cgtcgcaatg
     2281 ccaaggcagt taactttgga gtggtttatg ggatttcaga ctttggcttg tctaataatt
     2341 tgggaattag tcgtaaggaa gccaaagcct acattgatac ctactttgaa cgttttccag
     2401 gtattaaaaa ctacatggat gaagtggtgc gggaggcgcg tgataagggc tatgtagaga
     2461 ccctctttaa gcgtcgccgt gagttgccag atatcaattc gcgcaacttc aatattcgtg
     2521 gttttgcgga gcgaactgct atcaactcac ctatccaggg ttcggcagca gatattctca
     2581 agattgccat gattcagctg gataaagcct tggttgcagg tggttatcag actaagatgc
     2641 tgttacaagt gcacgatgaa atcgtccttg aagtgcctaa atctgaattg gtagagataa
     2701 aaaaattggt gaaacaaacc atggaagaag ccattcaact cagtgttcct cttatcgcag
     2761 atgagaatga aggggcaacc tggtacgagg ctaaataaaa agggggctag tcctcctttt
     2821 ttgtagtaga attctgcaaa ccttttcaaa atgtgctata ctgatgaaaa aggaggattt
     2881 ctatgagtca agaatttatc aatccaagtg atggcgtgat tcgtcagtat ctcgcaacga
     2941 gtaaaaccct tgctgtggtg ggtttgtctg accgtgaaga aacaaccagc aatcgagtaa
     3001 caaaggaaat gcaggctcgg ggctataaaa tcatcccagt caatcccaag gcggcaggtg
     3061 gcgaaatctt gggtgaaaag gcttatgcta gcctcgctga aattcctttt cctgtagata
     3121 ttgtcaatgt ttatcgtcgc agtgaatttc tgcccgatgt ggcgcgtgat tttctcaaag
     3181 ctgatgccaa gattttttgg gcacagctag gacttgaaag tttagaagca aaagagattt
     3241 tgcgtgatgg tggatgtgat gatatcgtga tgaatcgctg tatcaagaga gaacatactc
     3301 gcttgattga ggaagcataa gaaaaaggta gctgatgggc taccttttgt gttatactca
     3361 atgaaaatca aagagcaaac taggaaacta gctgcgggtt gctcaaaaca ccgttttgag
     3421 gttgcagata gaactgacga agtcagtaac atatacctac ggcaaggcga cgttgacgtg
     3481 gtttgaagag attttcgaag agtgttagaa aatgccgata agggtctgca taccaagagt
     3541 ggtgaggatg atggcaatcc agcagatggc tccaagaaga atggattttc cactggattt
     3601 gaccatagcg accagattgg ttttgagacc gatagcactc atggccatga caataaggaa
     3661 tttagagagt tctttgagag gggtaaagaa actactggac acacctagag aggtgagtag
     3721 tgtagtgagg agagaggcaa ggataaagta aaggataaaa agtgggaaga cttttttcag
     3781 ttgtaggctt tgcttgtttt cttgttggcg actttgccag taggatagaa agagcgtgat
     3841 agggataatg gccaaagtac gtgtgagttt aacaatggtt gcagactcga gggtattgct
     3901 ttggtaaaga ctgtcccaag cgctggcggc agccgttaca gaggaagtgt cgttgaccgc
     3961 agtccctgca aagagggcga agccttcatt ggatagatga agccaggtgc cgagggttgg
     4021 aaagatgagc gcagccaaga cattgaagaa aaagataacg gaaatggctt gggctacttc
     4081 cttttcctta gcattaataa cgggcgctgt cgctgcaatg gcagaacccc cacagataga
     4141 agaacctact ccaaccaagg tagccagttt tgtatccagt gcaaagaaac gctggaagag
     4201 gtaggcaata atcagagcta ttgagatagt ggacaggatg acagggagtg aagattggcc
     4261 aactgcgaag acctgcgaga tattgagacc aaaaccaagc aagacaacgg catattggag
     4321 caacttcttg gaactaaagg tcaaaccagc atccagttgt ttataggacg agagaaaggg
     4381 atgtaggagc atgcctatga aaatggcaaa aacgggcgcg ccaatcacag ggaagaatcc
     4441 tcctaagtac caagatacga tagaaatgag aaggcaggcc aagatacctg ctccattttt
     4501 tgatagaaat gacataaaaa cctccaaata aaatctatta ccattataga cctataaaca
     4561 ggaaaagtaa aatagaaagt ggaaagctat tctctaatgt atttttgcgg tcgggaggct
     4621 tttgtagtat aatagagata cgttttgaaa gtaggaggta tctatggact taactaagcg
     4681 ctttaataaa cagttagata agattcaagt ttcgttgatt cgtcagtttg accaggctat
     4741 ttcggagatt cctggggtct tgcgtttgac cttgggggaa cctgatttta caacgccaga
     4801 ccatgtcaag gaggcggcca agcgagcgat tgatcagaac caatcctact atacagggat
     4861 gagtggtctg ctgactctac gtcaggcagc tagtgacttt gttaaggaaa agtaccaact
     4921 ggactatgct cctgaaaatg aaatcttggt tacaattggg gcgacagagg ctttatctgc
     4981 gactttgacg gctattttgg aagagggaga caaggtactt ttgccagctc ctgcttatcc
     5041 aggctatgaa ccgattgtta acttagttgg ggcagaaatt gttgagattg atacgactga
     5101 aaatggtttt gtcttgactc ctgagatgtt ggagaaggcc attttggagc agggtgataa
     5161 gctcaaagcg gttattctca actatccagc caatccgaca ggaattacct acagtcgaga
     5221 gcagttagag gccttggcag ctgttttacg caagtacgaa atttttgttg tctgtgatga
     5281 ggtttactca gaattgacct acacaggcga agcccatgtg tctctaggaa cgatgttgaa
     5341 agaccaggct attattatca atggtttgtc taaatcgcat gccatgacag gttggcgttt
     5401 ggggctgatt ttcgctcctg cggccttcac agcccagtta atcaagagtc accaatactt
     5461 ggtcactgcc gcaaatacca tggcgcaaca tgctgcggta gaagccttga cggctggtaa
     5521 aaatgatgcg gagcccatga agaaggaata tatccagcgt cgggactata tcatcgaaaa
     5581 aatgactgct cttggttttg agattatcaa accagacggt gccttctata tttttgctaa
     5641 aattccagcg ggctacaatc aagactcctt tgcttttctg aaggattttg ctcagaagaa
     5701 ggccgttgcc tttatccctg gtgcagcctt tggacgttac ggggaaggct acgtccgcct
     5761 atcttatgca gccagcatgg agactatcaa agaagccatg aaacgacttg aggagtacat
     5821 gagagaagca tgattcagtc tatcacgagt caaggcttgg tgctttacaa tcgcaatttt
     5881 cgtgaggatg acaagctcgt caaaattttt acagagcagg ttggcaaacg catgtttttt
     5941 gtcaaacacg ctggtcagtc taagctggcg cctgttattc agcccttggt gttggcacga
     6001 tttctcttgc gaatcaatga tgacggactc agttacatcg aagactatca tgaggtcatg
     6061 acttttccca agattaatag tgacctcttt gtcatggcct atgcgaccta tgtggcagct
     6121 cttgcagatg ctagtttgca ggacaatcag caggatgctc ccttgtttgc ttttttgcaa
     6181 aagactttgg agttgatgga agcaggcttg gattatcagg ttttgaccaa tatttttgaa
     6241 attcaaattt tgactcgatt tggaatcagc ctcaatttta atgagtgtgt cttctgccat
     6301 cgggttggtc aggcttttga cttttctttc aaatatggag cctgcctctg tccagagcat
     6361 tatcatgagg ataagagacg ttgtcatctc aatcccaata tcccctatct gctcaatcaa
     6421 tttcaagcta ttgattttga gactttggag accatttcgc tcaagcctgg aatcaagcaa
     6481 gagctacgcc aatttatgga tcaattatat gaagagtacg ttgggattca cctaaaatca
     6541 aagaaattta ttgattccct agcagactgg ggacaattac taaaagagga aaagaaatga
     6601 aaaaaatcgc agtagatgcc atggggggcg attacgcacc tcaggccatt gttgagggtg
     6661 tcaatcaagc cctatctgac ttttcagata tcgaggttca actttacgga gatgaagcta
     6721 aaatcaagca atatctgaca gcgacagagc gcgtcagcat tatccatacg gatgagaaga
     6781 ttgattcgga tgatgaacct acgagagcta ttaggaataa gaaaaatgcc agtatggtat
     6841 tggcagccaa ggctgtcaaa gatggtgaag cagacgctgt cctttcggct gggaatacag
     6901 gtgccttgtt ggcagcagga ttcttcatcg tgggtcgtat caagaatatc gaccgtcctg
     6961 gactcatgtc taccttgcct accgttgatg gaaaaggttt tgacatgcta gaccttggtg
     7021 ccaatgcaga aaatacagcc cagcacctcc atcaatatgc ggttctaggt tccttctatg
     7081 ctaaaaatgt ccgtggcatt gcgcaaccac gcgttggttt gctcaacaac ggaacagaga
     7141 gtagcaaggg cgacccgctt cgtaaggaaa cttatgaatt actggcggct gatgaaagtt
     7201 tgaactttat cggaaacgtg gaagcgcgtg atttgatgaa tggcgttgca gatgttgttg
     7261 tggcagatgg tttcacggga aacgctgtgc tcaaatccat cgaagggaca gctatgggaa
     7321 tcgtgggctt gctcaagaca gctattacag gtggtggtct tcgagcgaaa ctaggtgccc
     7381 tccttctcaa ggacagcctc agtggtttga aaaaacagct caattattca gatgttggtg
     7441 gagcggtctt gtttggtgtt aaggcacctg ttgtcaagac tcatggctca agcgatgcca
     7501 aggctgttta tagtacgatt cgtcagattc gtaccatgct agaaacagac gtggttgccc
     7561 agactgcgcg tgaattttca ggagaataaa agagatgaca gaaaaagaaa tttttgaccg
     7621 tattgtgacc attatccaag agcgacaggg agaggacttt gtcgtgacag aatccttgag
     7681 tctgaaagac gatttggatg cggattctgt tgacttgatg gagtttatct tgactctgga
     7741 agatgaattt agtatcgaaa tcagcgatga ggaaattgac caactccaaa gtgtaggaga
     7801 tgtggttaaa atcattcaag gaaaatagca atcggagttc caagtcaacg gaagtagatg
     7861 gtttttagaa atgagaaata ttggacaagc tggtaaaatc ttggctgaca gtggttatca
     7921 agggctcatg aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc
     7981 gctaacagtt gaagataaag cctgtaacca tgcgctatct aaggagagaa gcaaggttga
     8041 gaacatcttt gccaaagtaa aaacgtttaa aatgttttca acaacctatc gaaatcatcg
     8101 taaacgcttc ggattacgaa tgaatttgat tgctggtatt atcaatcatg aactaggatt
     8161 ctagttttgc aggaagtcta atagtaaaaa agtgattaga aaacatcttt tttaaaaata
     8221 gagatgattt tgaaacaaaa aagctaattc aagacgtttc gatgccaatt caagatttgg
     8281 atgaaaaaaa ttaatagata ctgttatact aaacttgtca agtttgtaac aagacaaata
     8341 ttaaaaataa aaaagaggta ttcgttatga atacaaaaaa gatgtcacaa tttgaaatta
     8401 tggatactga gatgcttgct tgcgttgaag gtggcggatg caattgggga gattttgcca
     8461 aagcaggtgt tggaggagga gcagcacgag gtcttcagct aggaattaaa acaagaacat
     8521 ggcaaggtgc ag
//
LOCUS       DAVIME010000068         8426 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVIME010000068 DAVIME010000000
VERSION     DAVIME010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.068"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..2350
                     /gene="rnr"
                     /locus_tag="VV588_001963"
     CDS             <1..2350
                     /gene="rnr"
                     /locus_tag="VV588_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU7084240.1"
                     /translation="DRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMERKH
                     QIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAIDG
                     DTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQKI
                     SQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVLES
                     MDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIKAL
                     KNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSLNP
                     QVDRLTQSAIMEIDKHGRVVNYTIIQTVIKTSFRMTYSDVNDILAGDEEKRKEYHKIV
                     PSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIESF
                     MLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQEAL
                     QDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPDLL
                     VHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYVGE
                     EYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVGQQ
                     IRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKSGR
                     SNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            2313..2780
                     /gene="smpB"
                     /locus_tag="VV588_001964"
     CDS             2313..2780
                     /gene="smpB"
                     /locus_tag="VV588_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU7084241.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            2796..3656
                     /gene="tehB"
                     /locus_tag="VV588_001965"
     CDS             2796..3656
                     /gene="tehB"
                     /locus_tag="VV588_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU7084242.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            3729..4682
                     /gene="coiA"
                     /locus_tag="VV588_001966"
     CDS             3729..4682
                     /gene="coiA"
                     /locus_tag="VV588_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU7084243.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIQQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            4701..6503
                     /gene="pepF"
                     /locus_tag="VV588_001967"
     CDS             4701..6503
                     /gene="pepF"
                     /locus_tag="VV588_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU7084244.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            6505..7218
                     /locus_tag="VV588_001968"
     CDS             6505..7218
                     /locus_tag="VV588_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU7084245.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEEFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            7285..8226
                     /gene="prsA"
                     /locus_tag="VV588_001969"
     CDS             7285..8226
                     /gene="prsA"
                     /locus_tag="VV588_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU7084246.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(8343..>8426)
                     /locus_tag="VV588_001970"
     CDS             complement(8343..>8426)
                     /locus_tag="VV588_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU7084247.1"
                     /translation="IDYYNNKRIKVKLKGLSPVQYRTKSFR"
BASE COUNT         2718 a         1572 c         1863 g         2273 t
ORIGIN      
        1 agatagaata aaagaatatt tacaagacaa gggaaaggtg actgttaatg atttggctca
       61 ggctttggga aaagacagtt ccaaggattt tcgtgagttg attaaaacct tgtccttaat
      121 ggaaagaaag caccagattc gctttgaaga agatggcagt ctgaccttgg aagccaagaa
      181 aaaacatgag attaccctca aggggatttt tcatgcccat aaaaatggtt ttggttttgt
      241 cagcctagaa ggggaagagg acgacctttt tgtagggaaa aatgatgtca actatgctat
      301 tgatggtgat accgtcgagg tagtgattaa gaaagtcgct gaccgcaata agggaacagc
      361 agcagaagcc aaaattattg atatcctaga acacagtttg acaacagttg tcgggcaaat
      421 cgttctggat caggaaaagc ctaagtatgc tggctatatt cgttcaaaaa atcagaaaat
      481 cagtcaaccg atttatgtta agaaaccagc cctaaagtta gaaggaacag aagttctcaa
      541 ggtctttatc gataaatacc caagcaagaa acatgatttc tttgtcgcga gtgttctcga
      601 tgtagtggga cactcaacgg atgtcggaat tgatgttctt gaggtcttgg aatcaatgga
      661 cattgtatcc gagtttccag aagctgttgt taaggaagca gaaagtgtgc ctgatgctcc
      721 gtctcaaaag gatatggaag gtcgtctgga tctaagagat gaaattacct ttaccattga
      781 cggtgcggat gccaaggact tggacgatgc agtgcatatc aaggctctga aaaatggcaa
      841 tctggagctt ggagttcaca tcgcagatgt ttcttattat gtgaccgagg ggtctgccct
      901 tgacaaggaa gcccttaacc gtgcgacttc tgtttacgtg acagaccgag tggtgccaat
      961 gcttccagaa cgactatcaa atggcatctg ctctctcaat ccccaagttg accgcctgac
     1021 ccagtctgct attatggaga ttgataaaca tggtcgtgtg gtcaactata ccattataca
     1081 aacagttatc aagaccagtt ttcgtatgac ctatagcgat gtcaatgata tcctagctgg
     1141 cgatgaagaa aagagaaaag aatatcataa aattgtacca agtatcgaac tcatggccaa
     1201 gcttcatgaa actttagaaa acatgcgtgt gaaacgtgga gccctcaatt ttgataccaa
     1261 tgaagcgaag attttagtgg ataaacaagg taagcctgtt gatatcgttc ttcggcagcg
     1321 tggtattgcc gagcggatga ttgagtcttt tatgttgatg gctaatgaaa cagttgccga
     1381 acatttcagc aagttggatt tgccttttat ctatcgaatt cacgaggagc ctaaggctga
     1441 aaaggttcag aagtttattg attatgcttc gagttttggc ttgcgcattt atggaactgc
     1501 cagtgagatt agtcaggagg cacttcaaga catcatgcgt gctgttgagg gagaacctta
     1561 tgcagatgta ttgtccatga tgcttcttcg ctctatgcag caggctcgtt attcggagca
     1621 caatcacggc cactatggac tagctgctga ctattatact cactttacca gtccaattcg
     1681 tcgttatcca gaccttcttg ttcaccgtat gattcgggat tacggccgtt ctaaggaaat
     1741 agcagagcat tttgaacaag tgattccaga gattgcgacc cagtcttcca accgtgaacg
     1801 tcgtgccata gaagctgagc gtgaagtcga agccatgaaa aaggctgagt atatggaaga
     1861 atacgtgggt gaagagtatg atgcagttgt atcaagtatt gtcaaattcg gtctctttgt
     1921 cgaattgcca aacacagttg aaggcttgat tcacatcact aatctacctg aattttatca
     1981 tttcaatgag cgtgatttga ctcttcgtgg agaaaaatca ggtatcactt tccgagtggg
     2041 tcagcagatc cgtatccgtg ttgaaagagc ggataaaatg actggagaga ttgatttttc
     2101 attcgtacct agtgagtttg atgtgattga aaaaggcttg aaacagtcta gtcatagtgg
     2161 cagagggcgt ggttcaaatc gtcgttcgga taagaaggaa gacaagagaa aatcaggacg
     2221 ctcaaatgat aagcgtaagc attcacaaaa agacaagaag aaaaaaggaa agaaaccttt
     2281 ttacaaggaa gtagctaaga aaggagccaa gcatggcaaa gggcgaggga aaggtcgtcg
     2341 cacaaaataa aaaggcacgc cacgactata caatcgtaga tacgctagag gcagggatgg
     2401 tcctgactgg aactgaaatc aagagtgtac gagctgctcg aattaatctc aaggatggct
     2461 ttgctcaagt gaaaaatgga gaagtttggc tgagcaatgt tcatatcgcg ccttacgaag
     2521 agggcaatat ctggaaccag gaaccagaac gtcgtcgtaa actcctgctc cataaaaggc
     2581 aaattcaaaa attggaacaa gagaccaaag ggacaggaat gaccttagtt ccccttaagg
     2641 tctatataaa agatggctac gctaagcttc ttttaggact tgccaaaggg aagcatgact
     2701 atgacaaacg ggagtctatc aaacgtcgtg agcaaaatcg agatatcgcg cgtgtgatga
     2761 aagctgttaa tcagcgataa aaagaggaat tgaaaatgga aaaattagtt gcctataaac
     2821 gcatgccttt gtggaataaa caaacaatgc ctgaagctgt tcagcaaaag cacaatacaa
     2881 aagttgggac ttgggggaaa attactgtct tgaagggagc tctcaagttt attgaattga
     2941 cagaagaagg ggaagttcta gctgaacacc tctttgaagc aggggcagac aatccaatgg
     3001 cccaacctca agcctggcac cgagtggaag ctgccacaga tgatgtggaa tggtacttgg
     3061 aattttattg taaacctgag gattattttg ctaaaaaata caataccaat cctgttcatt
     3121 cagaggtcct agaggccatg gagacagtga aacaagggaa agctttggat ttgggttgtg
     3181 gtcaggggcg taattctctt tttctagccc agcaagattt tgatgtgacg gctgtagatc
     3241 aaaatggact agctcttgaa atcttgcaaa gcattgtgga gcaggaagat ttggacatgc
     3301 ctgttggcct ttacgatatc aattcagcta gcattgaaca agaatatgat tttatcgttt
     3361 caacagttgt tctcatgttt ctacaagcgg accgcattcc agctattatt caaaatatgc
     3421 aggagaaaac cagtgttggt ggttacaacc ttatcgtttg tgccatggac acggaggatt
     3481 atccttgctc ggttaacttc ccattcacct ttaaagaagg agaactggca gactattaca
     3541 aggattggga attggttaag tacaatgaaa atccaggcca tttgcatcgt cgcgatgaga
     3601 atggcaatcg tattcaacta cgctttgcga ccttactagc taagaaaatc aagtaaacac
     3661 acatgaagat taggaatttt cctgatcttt tttctttttt acgaatgata tagaaaagga
     3721 gggaattcat gtttgttgcg agagatgcta ggggagaatt ggtaaatgtg ttagaggata
     3781 aacttgagaa gcaagcatac acctgcccag cttgtggagg ccagctccat ttgcgtcaag
     3841 gaccaagtgt acggacgcat tttgcccata aatccttaaa agactgtgat tttttctttg
     3901 aaaatgaaag tccagaacac ctggccaata aggaatccct ctatcactgg ttgaaaaaag
     3961 agacaaaggt tcaattagag tacccgcttt cagaacttaa acagattgcg gatgtatttg
     4021 taaatggcaa tctagctcta gaagttcagt gtagtccctt gcctcagaaa gtccttaaag
     4081 agcgaagtga gggctatcgt agtcagggtt accaagtact gtggttgctg ggtcaaaaac
     4141 tgtggctcaa ggagcgtttg actcgtctac agcaaggttt tctttatttc agtcaaaaca
     4201 tgggctttta tgtttgggaa ttagacaagg aaaaacaagt tttaagactc aaatacctga
     4261 tttaccagga tctccgcggt aaactccatt atcaaatcaa ggaattttcc tatggtcaag
     4321 gtagtttatt ggaaatattg cgtcttccct ataagagaca aaaaatatct cattttacag
     4381 tttctgagga caaggacatc tgtcgctata tccagcaaca actttattat caaaatctct
     4441 tttggatgaa agaacaagca gaagcctatc aaaagggaga aaatatcctg acttatggac
     4501 tgaaagaatg gtatccacaa attcgaccaa tagtgggcaa atttttccag attgaacaag
     4561 acttgactag ctattatcag cacttttata cctattacca aaaaaatcct caaaatgatt
     4621 ggcaaaagct ttatccacca gccttttatc agcaatattt cttgaaaaat atggtagaat
     4681 agaaaggatg gaggaatcta atggtattac aaagaaatga aataaatgaa aaagatacat
     4741 gggatctatc aacgatctac ccaactgacc aggcttggga agaagcctta aaagatttaa
     4801 cagaacaatt ggagacagta gcccagtatg aaggccatct cttggatagt gcggataacc
     4861 tactagaaat cactgaattt tctcttgaaa tggaacgcca gatggagaag ctttacgttt
     4921 atgctcatat gaagaatgac caggatacac gtgaagctaa gtatcaagag tactatgcca
     4981 aggccatgac actctacagc cagttagacc aagccttttc attctatgat cctgaattta
     5041 tggagattag cgaaaagcag tatgctgact ttttagaagc tcaaccaaag ctgcaggttt
     5101 atcaacacta ttttgacaag ctcttgcaag gcaaggatca cgttctttca caacgtgaag
     5161 aagaattatt ggctggagct ggagaaatct ttggttcagc aagtgaaacc ttcgctatct
     5221 tggacaatgc ggatattgtg ttcccttatg tcctagacga tgatggtaaa gaagttcagc
     5281 tatctcatgg gacttacaca cgtttgatgg agtctaaaaa acgtgaggtt cgccgtggtg
     5341 cctatcaagc tctttatgcg acttacgaac aattccaaca cacctatgcc aaaaccttgc
     5401 aaaccaatgt taaggtgcaa aattaccgtg ctaaagttcg taactacaag agtgctcgtc
     5461 atgcagccct cgcagcgaat tttgttccag aaagtgttta tgacaatttg gtagcagcag
     5521 ttcgcaagca tttgccactc ttacatcgct atcttgagct tcgttcaaaa atcttgggga
     5581 tttcagatct caagatgtac gatgtctaca caccgctttc atctgttgaa tacaatttta
     5641 cctaccaaga agccttgaaa aaagcagaag atgctttggc agtcttgggt gaggattact
     5701 tgagccgtgt caaacgtgcc ttcagcgagc gttggattga tgtttacgaa aatcaaggca
     5761 agcgttcagg tgcctactct ggtggttctt acgataccaa tgcctttatg cttctcaact
     5821 ggcaggacaa tctggacaat ctctttactc ttgttcatga aacaggtcac agtatgcatt
     5881 caagctatac tcgtgaaact cagccttatg tttacggaga ttactctatc tttttggctg
     5941 agattgcctc aactaccaat gaaaatatct tgacggagaa attattggaa gaagtggaag
     6001 acgacgcaac acgctttgct attctcaata acttcctaga tggtttccgt ggaacagttt
     6061 tccgccaaac tcaatttgct gagtttgaac acgccattca ccaagcagat caaaatgggg
     6121 aggtcttgac aagcgatttc ctaaataaac tctacgcaga cttgaaccaa gagtattatg
     6181 gtttgagtaa ggaagacaat cctgaaatcc aatacgagtg ggctcgcatt ccacacttct
     6241 actataacta ctatgtatat caatattcaa ctggctttgc ggccgcctca gccttggctg
     6301 aaaaaattgt ccatggtagt caagaagacc gtgaccgcta tatcgactac ctcaaggcag
     6361 gtaagtcgga ctatccactt aatgtcatga gaaaagctgg tgttgatatg gagaaggaag
     6421 actacctcaa cgatgccttt gcagtctttg aacgccgttt aaatgagttt gaagcccttg
     6481 ttgaaaaatt aggattggca taaaatggtt gaatcgtata gtaagaatgc taaccataac
     6541 atgcgtcgtc ctgtcgtcaa agaagaaatt gtagacttga tgcgtcagcg tcaaaagcag
     6601 gtcacaggtt tcttgaaaga attggaagaa tttgcccgca aggaaaatat tcctattatt
     6661 ccccatgaaa cggttgctta tttccgtttt cttatggaaa ccatgcagcc taaaaatatt
     6721 ctggaaattg ggacggctat cggtttttca gctctcttga tggctgaaca tgcgccaaat
     6781 gctaagatta caactattga tcgtaatcca gaaatgattg gttttgccaa ggaaaatttt
     6841 gcccagtttg acagtcgcaa gcaaatcact ctcctagagg gagatgcggt ggatgtctta
     6901 tctacactga cagagtctta tgatttcgtc tttatggatt ctgccaagtc taaatacatc
     6961 gtctttctgc cagaaatcct caaacatttg gaagttggtg gtgtggttgt cttggatgat
     7021 atttttcaag gtggtgatgt tgccaaggat attatggaag tccgtcgtgg tcagcgaacc
     7081 atttatcgag gccttcaaaa attatttgat gcaaccttag acaatccaga actcaccgca
     7141 acattagtgc ctttaggaga tggtattctc atgcttcgta aaaatgtagc agatgttcaa
     7201 ctgtctgaaa gcgaatgatt ttcagaaaaa tttaagaaaa aatagtaaaa tagatagagt
     7261 aacacttatc tcaaaggagt agacatgaag aaaaaattat tggcaggtgc catcacacta
     7321 ttatcagtag caactttagc agcttgttcg aaagggtcag aaggagcaga ccttatcagc
     7381 atgaaagggg atgtcatcac agaacatcaa ttttatgagc aagtgaaaaa caacccttca
     7441 gcccaacaag tcttgttaaa tatgaccatc caaaaagttt ttgaaaaaca atatggctca
     7501 gagcttgatg ataaagaggt tgatgatact attgccgaag aaaaaaaaca atatggcgaa
     7561 aactaccaac gtgtcttgtc acaagcaggt atgactcttg aaacacgtaa agctcaaatt
     7621 cgtacaagta aattagttga gttggcagtt aagaaggtag cagaagctga attgacagat
     7681 gaagcctata agaaagcctt tgatgagtac actccagatg taacggctca aatcatccgt
     7741 cttaataatg aagataaggc caaagaagtt ctcgaaaaag ccaaggcaga aggtgctgat
     7801 tttgctcaat tagccaaaga taattcaact gatgaaaaaa caaaagaaaa tggtggagaa
     7861 attacctttg attctgcttc aacagaagta cctgagcaag tcaaaaaagc cgctttcgct
     7921 ttagatgtgg atggtgtttc tgatgtgatt acagcaactg gcacacaagc ctacagtagc
     7981 caatattaca ttgtaaaact cactaagaaa acagaaaaat catctaatat tgatgactac
     8041 aaagaaaaat taaaaactgt tatcttgact caaaaacaaa atgattcaac atttgttcaa
     8101 agcattatcg gaaaagaatt gcaagcagcc aatatcaagg ttaaggacca agccttccaa
     8161 aatatcttta cccaatatat cggtggtgga gattcaagct caagcagtag tacatcaaac
     8221 gaatagtcca aatcaatgag tcagggaaaa aaactcgact tcaggaaaaa atgaagcaaa
     8281 cattcccaaa ataaaacgca tagtacaagg tttgtactgc ccccaaaagt tagacaatta
     8341 atttatctga aggatttagt tctgtattgc acagggctaa gtccttttag ttttacctta
     8401 attctcttat tgttgtaata atcaat
//
LOCUS       DAVIME010000069         7804 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVIME010000069 DAVIME010000000
VERSION     DAVIME010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.069"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            143..2125
                     /locus_tag="VV588_001971"
     CDS             143..2125
                     /locus_tag="VV588_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU7084248.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSEEQKTSTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2426..7729
                     /locus_tag="VV588_001972"
     CDS             2426..7729
                     /locus_tag="VV588_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU7084249.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKVTFLVTGAETGD
                     TWVGIYSTGNASNTRSDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
BASE COUNT         2563 a         1482 c         1715 g         2044 t
ORIGIN      
        1 tatagttgag ggatttttaa atgatattca tattttttgc aaagatgttg tttgaaaaat
       61 aattttcaaa aattctgaaa attctgttga caactttctg aaaagagtct ataatggaga
      121 gaaagtttta aaggagaaaa tgatgaaaag ttcaagacta tttgcccttg cgggcgtgac
      181 attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca ctaaaggtga
      241 gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt tgacaactgc
      301 taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag aaaatgatcg
      361 ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg atggattgac
      421 ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg aagaatacgc
      481 ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata aaaaatcaga
      541 tgctctttac cttgttcaag aatcaatcaa agggttggat gcctatgtaa aaggggaaat
      601 caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc agtacacttt
      661 gaacaaacca gaaagcttct ggaattctaa gacaaccatg ggtgtgcttg cgccagttaa
      721 tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc caagtagtct
      781 cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg ttgaatttgc
      841 gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta aattgtcatt
      901 ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta gccttacagc
      961 agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta tgaaggacaa
     1021 tattgtctat actcaacaag actctattac gtatctagtt ggtacaaata ttgaccgtca
     1081 gtcctataaa tatacatcta agaccagtga agaacaaaaa acatctacga aaaaggctct
     1141 cttaaacaag gatttccgtc aggctattgc atttggattt gaccgtacag cctatgcctc
     1201 tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg ttccaccaac
     1261 atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat tggtcactta
     1321 tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt acaatccaga
     1381 aaaagccaag gctgaatttg ctaaagctaa atcagcttta caagcagaag gtgtgacttt
     1441 cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc agcgcgtcca
     1501 atctatgaaa caatccttgg aagcaacttt aggagcggat aatgtagtca ttgatattca
     1561 acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg ctgctggtga
     1621 agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc catcaaccta
     1681 ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag ggtttgactc
     1741 aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa aattggttac
     1801 tgaggctggt gatgagacta cagatgttgc taaacgctat gataaatacg ctgcagccca
     1861 agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag ggcgtccaat
     1921 cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata aaggcacaag
     1981 tgaaccagtc ttgtataaat acttggaact tcaagacaag gcagtcactg tagatgaata
     2041 ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa aggctcaaga
     2101 agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt tagtatttcc
     2161 cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta ctgaccccca
     2221 aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta cttgtttcct
     2281 attgctttct cagctattat ttgttatatt aaaagcataa ttatttttta tttatcaggg
     2341 ttaagcattg cactttcaga ggaaggagta ttttttaaaa aggaaatgta aacgcttgct
     2401 aaaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac gttgtaaata
     2461 tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg cattctttgg
     2521 gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact taccagctga
     2581 tttagctact gctcttgcaa cagcaaaaga gaatgatgga cgtgattttg aagcgcctaa
     2641 ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag aagaagaact
     2701 attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata aacctgcagc
     2761 tgctaaacct gaaacaccta agacggtaac ccctgaatgg caaacggtag agaaaaaaga
     2821 acaaaaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc aactatcctc
     2881 aactgctcaa aatgataacg caggaaaacc agccctgttt gaaaagaagg gcttgaccgt
     2941 tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gatgattctg aaaagggcaa
     3001 atcacgcttt ggtgtcttcc tgaaatttaa agataccaat aataatgttt ttgtcggtta
     3061 tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt ggtatagagg
     3121 tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca ctctcaagtc
     3181 agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag tgactctacc
     3241 agctgcggtc aatgaccatc ttaaaaatga gaagaagatc cttctcaagg cgggctctta
     3301 tggcaatgac cgtacggttg tcagcgttaa aacagacaat caagaaggcg taaaagcgga
     3361 tgatactcct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg tgacttatga
     3421 tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc gtgtcaagga
     3481 atacagcttg aacgggcata ctttgccagg acaggtgcaa cagttcaacc aagtctttat
     3541 caataaccac cgaatcaccc ctgaagtcac ttataagaaa atcaatgaga caacagcaga
     3601 gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga cagtacgcct
     3661 gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc acaatcaagt
     3721 cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta gtttcctcgg
     3781 caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg gggcaaccat
     3841 gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc caatgaaaga
     3901 cctagccaag ggttacatgt atggatttgt ttctacagat aagcttgctg ctggtgtttg
     3961 gagtaactct caaaacagct atggtggtgg ttcgaatgac tggactcgtt tgacagctta
     4021 taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat ggcaatggga
     4081 aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa gggctaaggt
     4141 tgttatcact gaagatgcca atgcagacaa gaaagtcgat tggcaggatg gtgccattgc
     4201 ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata tcacagctta
     4261 ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga ccttggatgg
     4321 tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc ttaaaggata
     4381 tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta agcgtatcgg
     4441 tggtgtcgaa gacttcaaga ccctgattga gaaggctaag aaatatggag ctcatctagg
     4501 tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg aaaaaattct
     4561 ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc aaggtatcaa
     4621 cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag atttgaagaa
     4681 aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg gtcaatcagg
     4741 tgataacggt gcctgggcta cccacgttct tgctaaagaa attaacaaac aaggctggcg
     4801 ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc actgggcagc
     4861 tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca cccgctttat
     4921 ccgtaaccac caaaaagatg cttgggtagg ggactacaga agttatggtg gtgcagccaa
     4981 ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag gaagaagtga
     5041 ctacaatggc tatgtgacta acctctttgc tcatgacgtc atgactaagt acttccaaca
     5101 cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata acggtagcac
     5161 ctataaatgg actccagaaa tgcgagtgga gttggtagat gctgacaata ataaagtagt
     5221 tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta cagtaacgct
     5281 caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact gggatgcaaa
     5341 tggtaagaaa ctttctactg agaaggaaaa gatgtactac ttcaatacgc aggccggtac
     5401 aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt acaagctaac
     5461 tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa ttaccctaga
     5521 tcttctagca aatcaaccat acgtacttta ccgttcaaaa caaaccaatc ctgaaatgtc
     5581 atggagtgaa ggcatgcaca tctatgacca aggatttaat agtggaacct tgaaacactg
     5641 gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg caaacgatat
     5701 gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa ctggcttgaa
     5761 accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg ccaaggcaag
     5821 tatcactgtg aatactggtg aaaaagaagt gactacttat accaataagt ctctcgccct
     5881 caactatgta aaagcctacg cccacaatac acgtcgtaac aatgctacag ttgacgatac
     5941 aagttacttc caaaacatgt acgccttctt tacaactgga tcggacgtct caaatgttac
     6001 tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa ttcgtacctt
     6061 tgaaaacaat tcaagcatgt acggagacaa gcatgataca ggtaaaggca ccttcaagca
     6121 agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg ttgaaggtgt
     6181 tgaagataac cgcactcact tgtctgaaaa acacgatcca tatacacaac gtggttggaa
     6241 tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa atggactagt
     6301 gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg aagcaggtaa
     6361 gacctaccgt gtaacctttg aatacgaagc aggttcagac aatacctatg cttttgtagt
     6421 cggtaaggga gaattccagt caggtcgtcg tggtactcaa gcaagcaact tggaaatgca
     6481 tgaattgcca aatacttgga cagattctaa gaaagccaag aaggtaacct tccttgtgac
     6541 aggtgcagaa acaggggata cttgggtagg tatctactca actggcaatg caagtaatac
     6601 tcgtagtgat tctggtggaa atgccaactt ccgtggttat aacgacttca tgatggataa
     6661 tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg ctctgaagaa
     6721 ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg ctttgaaaga
     6781 ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag cgcgtgcaga
     6841 gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgg ctttggtagc
     6901 agaagacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg caaatgcctt
     6961 tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg taggcaagcc
     7021 tgcaaccatg gtcttgaaag aagcaactga aatcactgga cttcgttatg ttccacgtgg
     7081 atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg agtctggcaa
     7141 ggagcatacc tttactgcaa ctgattggcc agataacaat aagccaaaag acattgattt
     7201 tggtaagaca attaaggcta agaaaattgt ccttacaggt actaagactt acggagatgg
     7261 tggcgataaa taccaatctg cagcggaact tatctttact cgtccacagg tagcagaaac
     7321 acctcttgac ttgtcaggct atgaagcagc tttggctaag gctcagaaat taacagacaa
     7381 agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga cggataacca
     7441 tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat taaaagattc
     7501 tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta gctctttagt
     7561 ttccaatcaa ggtaagacgc cagattataa gcaagaaata gatagaccag aaacacctga
     7621 acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcttcc tagcaagtgt
     7681 tagtctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt atttagtaaa
     7741 acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt atagtacaga
     7801 aaaa
//
LOCUS       DAVIME010000070         7702 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVIME010000070 DAVIME010000000
VERSION     DAVIME010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7702
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.070"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..743)
                     /locus_tag="VV588_001973"
     CDS             complement(<1..743)
                     /locus_tag="VV588_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU7084250.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMT"
     gene            complement(758..1606)
                     /locus_tag="VV588_001974"
     CDS             complement(758..1606)
                     /locus_tag="VV588_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU7084251.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(1603..3078)
                     /locus_tag="VV588_001975"
     CDS             complement(1603..3078)
                     /locus_tag="VV588_001975"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU7084252.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(3401..4756)
                     /locus_tag="VV588_001976"
     CDS             complement(3401..4756)
                     /locus_tag="VV588_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU7084253.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(4766..5083)
                     /locus_tag="VV588_001977"
     CDS             complement(4766..5083)
                     /locus_tag="VV588_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU7084254.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(5100..5417)
                     /locus_tag="VV588_001978"
     CDS             complement(5100..5417)
                     /locus_tag="VV588_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7084255.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(5432..6328)
                     /locus_tag="VV588_001979"
     CDS             complement(5432..6328)
                     /locus_tag="VV588_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU7084256.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(6331..7593)
                     /locus_tag="VV588_001980"
     CDS             complement(6331..7593)
                     /locus_tag="VV588_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU7084257.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         2647 a         1694 c         1078 g         2283 t
ORIGIN      
        1 gtcattccca tgacaaagaa taacatccct ttaaaacagt atcttaccca attttcaggt
       61 aagacttttg atacaaccgt ccccaatacc cctccgcata tagaagcaag aaaaataact
      121 ggaacaggtg ctaaatgata ctgatttaaa cctgtaacca caacaattgt agccaaatga
      181 gacaactggg aaaagaaaat aattgcaaga gaatacatcg ttgcttcttt tatcgaaata
      241 gaaaaaaaca ccatcaataa agatacattg agcggaccac caccaatccc taaaaaacta
      301 gaaatcaagc ccaatagaag accacaaatc atatagaatc ctatcttatc aaattgataa
      361 gtttttttaa aatctgttaa aacaaatgat acaagtagca tcacaaatag taaaatcatt
      421 tgaacaatgg atactagccg tactgataat tgagataaca aaacttgaaa aataagatga
      481 cctagaaacc ctcctaaaac agaagaaaag gataccgtaa aaatcaatct ccattttatc
      541 tctttacttt gtgaaaatct tttggttgtt gaaataatcg ccattataaa aacagagaaa
      601 ctagaataaa aagcaatatc actgaccgaa tggtatccaa aactatccat aagtggctta
      661 attataattc caccacccat gcctgatata gaacccaatc cactagctat tataatgatt
      721 agaaaataaa taatctcaac cactttttaa gtccatccta ttctttcaaa catctaaaac
      781 ctagatggct actagtggaa gtagaaatac atccatttct agcagctact cggtatcgat
      841 tacaataaga acaatgacat aaaaaggaac ctcctctgat agcatactcc tcatcttgta
      901 tcccatattt tggcaactca tagtcatctt cattaaaact agctaataag gtatatctcg
      961 gattgcgaca ccattcccaa acattcccaa tcatttgata tagaccaaaa tcattaggta
     1021 aaaattcata gacaggagcc gttcctataa atccatctaa ggcagtattt tcataaggaa
     1081 atcttccttg ccaagtattg gcatgataat atccaccttc taaaagagta tctccccaag
     1141 gatattcaga ttgtcttcct cctctagcag catattccca ctgtgcttca gtcggtaaag
     1201 acattccgct ccaattacag aaagccaatg catcttctaa agcaacatga actactggat
     1261 ggtcttctaa acccactaga ttactattct caccgtaggg atgtttccag caagcgttcg
     1321 gaacttgtaa ccaccacgga gccccagcag gatgaggata tccctccctt tctgcctctg
     1381 gaacgaacaa tataaaaaca aaagaccact cttgtcgctc agctagtgtt ttatagcctg
     1441 tttctttcac aaattgagca aattcttgat tcgtaactgg agtatccgca atggaaaaat
     1501 cctttacact aacagcgact tgaggacctt caaaatcatc taaaaagccc tcttcagaat
     1561 ttgttcccat cataaatgtc ccacccttga tttttttcat tttcatgatt gactatcccc
     1621 cgttttcgtt agagttggcg ttattttaga aagttcaaca ggaactaact cttcatccac
     1681 aacaaaacct tcttctctat atctaagaaa gtctactaat tttttcttca tctgacgaac
     1741 aataggttgg tatttttcac ttggatacaa atcattcatt tcatgcggat cttttttcat
     1801 atcaaataac tgataatgat ttaaaacagg aaaccagata aatttccact ggtctgtcaa
     1861 gatatattga ctagaatctt ttcctaaagc atgttcacca tgaaattctg ttcgccaccc
     1921 ctcgtactgt ccaaataata aattcttaac actccgtcca tctagttcat ctgtagtagt
     1981 tcctcctgcc aaatccacga gtgaaggaaa aatatcttga attttcacta attgcttgat
     2041 tgttccccta ttaccagcta tcaatccagc cggatcgtaa ataaacgaag gaatgtggat
     2101 acttccctga taaggatatc cctttctaaa cagataatgt tcaccaagct gatctccatg
     2161 atccgaaaca aaccagataa tcgtatcttt atcatgacga aattctttta gggcagtcaa
     2221 aaagcgacta atttgatggt ctatatgagt aatcaatcca aaataagcag caaccattct
     2281 tctttgatca tcttccttta atttccctct taaagcataa atagacggaa tttgcttttc
     2341 taatacttcc caattcccga tatgcaaatc gagaaattga ggcaagcgtt ccatatacat
     2401 atcaaaatag tattttgggg gatttaatgg agcatgtggt ttttcaaaag acattttgag
     2461 aaaaaaagga accgttggat ctcttctttg taaaaatgaa atggactcac tcacaaccca
     2521 gtttgttgga tgtaacttct catctttatc ccaaggtcta gcttcccaag aattacaatc
     2581 cattccgtca tcaatcaaat caacatcata accaacttta ccctttaaaa aggctagata
     2641 gtcactagca taatcaaatt gacttccata agccttatca tactttctat caacatgtag
     2701 atacccatcg tgaagtaaga catgatcaaa cccaagtctc tgtctggaag gaaaaacatg
     2761 catcttacca atacactctg tttgataacc catatcttta aagacttttg gaagagtatt
     2821 agtaaaattc caaggcacct catcttgata accaactcgt ccacttttat cttggtctaa
     2881 gccagtcaat aaagctgccc tagcaggaac gcaagaagga actggagaat aggcattttc
     2941 aaaattataa cctacactag ccatcatatc taatgttgga gtgctaacta gcttatcctt
     3001 actattcaag gataaggcgt ctgctctcat ttgatctaca acaatcaaaa taatatttgg
     3061 ctgttttgtc tgaaccataa aatctccttt ctaatatggc aaaagaggca caagaagata
     3121 tctaccttta ctgcacccct ttctatatca atctctctat ataaaacaat aacattcttg
     3181 ttatgtttta tagaaaaatg aactaaaata tgactaaatc gattaggaaa ttcaaatcat
     3241 tttctagtac tgttttagaa gttacagtgt actattccaa cttcaataaa ctataaacct
     3301 ttgtctaata acaattttag tggagataag aaatcctaca cctaactcat cttacacgta
     3361 atctatttct attttatcac aaaaaacgca agtaagacca ttaactcaat tcagttttat
     3421 atgccatttt cacaaatggg aaataagtca agacactaat aatcaaacaa acaactgata
     3481 agatgatggc acgccaatca aatgctgtag agaagaaacc atataaaatt ggaggcatta
     3541 cccaagtaac gttttgtgta acaggtgaaa caagacccca gcttgttgcc cagtaagcta
     3601 ccgttgccat gaaaaccgga ctaagtacaa atggtataaa tagcaaagga ttcaagacaa
     3661 ctggtaaacc ataattgacc ggctcaccaa tattaaacag aactggtgct agaccaagtt
     3721 tagcaacttt tcgataatga ctgtttcttg aaaaaattaa aatagcaagt actaatccta
     3781 atcctccaaa ccagacaaac gccccaaaag acccacttgt ccatatataa ggaatcggtt
     3841 cacctttttg gaaagcatcc agattcgcta acatagcaac tccaaacagc ccttccatga
     3901 tgggagccaa tacatttcct ccatggagac caaaaaacca gaataactta ttcaaaaaga
     3961 tcatcagaat aactgcaaag aaactttgag acaaacctag taatggcgtt tgtaacacct
     4021 tgtaaaccca atcaatcaat aagtcattgc taagtaaatg gaaaacataa gtcaagatgg
     4081 ctactatata catcgccata aatcctggaa tgatagaagt gaacggctta gcaatcgcag
     4141 ggggaactga atctggtaac ttgattaccc agttcttttt cattacttta cagaaaataa
     4201 tagaggctaa aaatccaatc atcatggctg taaagtagcc tctggcatta atatggtttc
     4261 ctggaatcac attcccaata gttaccatca gatttttacc atcaaatgct agattatcaa
     4321 ttccttgtaa gatttgatct aatttcacat ctcctacatt tgccaaaggg aaactctttg
     4381 taactgtact tccaatcgaa atgacaaacg aagcaagtga taccaaacca gcagaaactg
     4441 tatcaacctt gtaaatctta gcgatattca ctcccaagca atagatgaac aacaaggaaa
     4501 caattggtat acttcccttg aataccaaat tattgatgtc aacaagccac tgaaaggttt
     4561 tcgtaatact ttctaggtga aattgttgtg gtaaatccac tagaaaagca tttaataaca
     4621 aagcaatgga acctgtcata ataacaggca tagtccccac aaatgaatca cgtaaagcaa
     4681 ctaaaaactt ctgattccca actttcattg caattggaga aagtttttct tgcattttat
     4741 ccaacattgt attcatacca aactcctaat ttttttcaaa tcgttcgtat acttctacca
     4801 cttctttcgc caagtcaaca aaagtcagac tcgtcattaa atgatcttgc gcgtgtacca
     4861 tcaagaggct aattgatgtt ttttccccct gtgcctctct tgtcaacatt tctgtttgag
     4921 ccttatgcgc ctgtaataag gcagcattcg catcagctaa tcttcgattg gctttagaga
     4981 aatccccttt ttttgctgcc tgaatagcct ccatagcatt acttttggct tccccaccat
     5041 acataattag ccccattaca gattctaaat tactttcatc cataacattc tcctcaatct
     5101 tagtctaata aactttcagc taaatctaaa actttagaac cattcatcat tccgtaatct
     5161 gtcatcggaa taaccgccac aggaatctgt ctatctttta gtttttcttg aaagtcccct
     5221 agtaaatagc gaacttgagg acctaaaagc aacacattta cttcttttgt tgctacaatt
     5281 tcttctgctt caggagctgg aactgcaaaa atttctgcat ccaacccctt atcttctgct
     5341 gccttttgca tctttgtcac tagcagactt gtactcatac ctgctgcaca tgctaacata
     5401 attgttactt tagccatagc ttactccttt atcacctatt tactgaccta gccaagcgag
     5461 atactgtatg tctcactcct ctaattgcct tgctcaatgc ataaatatta tcgactgttg
     5521 ccagtccccc atatcctgcg tcacctatat gttgaatatc aactccacaa attttatttc
     5581 taagtgcaat ttccttgata gtatctgtat cagatgtttc ttggctagta ccaatagcac
     5641 tcaatacaag accaccctta ctatgaacga gatcaacgac ttcacgcaac tcttggtcat
     5701 gaaaggctgg aacggttcca actgctggaa caagtatcac atccgcacct gcttccaaca
     5761 attgctctgc gacagaaagc tctgccacag gctcattcac tcctgccccg tgcattttac
     5821 cagctataat caaacctgag aaattctctt tagcagattg aactgctttg ataatctctt
     5881 gattgctaac tcctgttcca ggatttccag tcaaacagac aaagtcaaaa cctaactcct
     5941 ctattcgatt caatgtttca acactagcaa cacgacctgc aacaatttcc tgtgtttcct
     6001 ctagcatctt tgcagatggg tcaatcggtt ccaaatttac accaattgga caagcaacaa
     6061 gctggtgtaa gcgatgaata acatcatcac ctgaactatc caaagcataa attttaggct
     6121 caaaaacatc aacacaattc aataaaatca tatcagctcc aaaagctcta gcaatttcag
     6181 aattagttat atccccaaca aatgtctcac gagtaactac attttcagat agaacaactc
     6241 taccttcact tgctaaaata ctttgtttta attcttcagc attcatctgt aatatctcag
     6301 atggatttgc actaattaaa cgtttcattc tcaatcctcc aataacttaa accgtttttc
     6361 aatagctatt acaaatggta aataaagtaa gacatccaaa acaatcaata caatttgtaa
     6421 taatgaacca gaaatacttc ctgtagcaag taaaccactt ataacaggtg gcatagtcca
     6481 acctggatct gtataagtta gcggaaccaa acctgatgcc attgctcccc acgctactag
     6541 taagttaaac attggagcta agataaatgg aactagtaac aaaatgttca aaacaatagg
     6601 aacgccaaac attgctggtt catttatatt aaataatcca ggtataacag ttataggtgc
     6661 caaagttttt agttgtttac tagctttctt cttatgtgct aaatatccta acgcaagaac
     6721 taaacctatg gttgcaccac cgccacctat gaatacaaaa ttatccataa atacgctagt
     6781 aaaaatattt ggaagagttt ctccagtttg ataagctact ttatttgcat ctagattagc
     6841 taaccataac ggtttcataa ctgcattaac aacatttcct ccgtgtaatc ctacaaacca
     6901 aaaactacta ttaaggaaaa ttaagataag aagaccaata acattatttc ctaaaagtcc
     6961 aagtggacct cccaaagcta cttgagcaat ttcatgaaga ttaggtaaac ttaatttatc
     7021 taaagttgca taaacaatca accaaccaac aatagtcact gcaccaggaa taatggcact
     7081 aaagctttta gatactgctg gtggaacacc atccggcatt tttatctgta tattatgatt
     7141 tataaaccat tggtagatat agccattaat caatcctaaa atcatagcaa caaataaacc
     7201 ttttgatgcc atgaaagcgg taggcattcc tgctccagcc tctcctgtaa tgaaaggcgt
     7261 aactgtaata aaagatgata atgacacaat accagcagga ataccatcaa ctttgtattg
     7321 tctagccata aagtaagcga taccaaaact agctacaaga ccaagtaatc caaaactact
     7381 atcaacaccc ttccataaat agtcagcaac accaatatca cccagatatt tttcccatcc
     7441 tggaatagga aaacttgcaa taaccattag taatgaacct atcaacaata aaggtatagt
     7501 tagagtaata ccgtctcgaa tagaaaccaa cgctttatta ttacccaatc tagccgctac
     7561 tggaagtaac ttttcttgta ataatttttc cataaccttt tcctcttaaa tatattttat
     7621 tatcaaaagt tatcaattat ctttattttt tgacgtcaag ttgttatttg attatctttt
     7681 gttatttata ttttacaact at
//
LOCUS       DAVIME010000071         7478 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVIME010000071 DAVIME010000000
VERSION     DAVIME010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.071"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..367)
                     /locus_tag="VV588_001981"
     CDS             complement(<1..367)
                     /locus_tag="VV588_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084258.1"
                     /translation="MGGAYLSKSACQGICAALAMSPGTFIALTGAAVLTKKLINYIKV
                     GGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVY
                     IFLGYVLVIQKDVYLFSILI"
     gene            complement(406..744)
                     /locus_tag="VV588_001982"
     CDS             complement(406..744)
                     /locus_tag="VV588_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU7084259.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            1210..2073
                     /locus_tag="VV588_001983"
     CDS             1210..2073
                     /locus_tag="VV588_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7084260.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(2259..2729)
                     /locus_tag="VV588_001984"
     CDS             complement(2259..2729)
                     /locus_tag="VV588_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU7084261.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(2695..3501)
                     /locus_tag="VV588_001985"
     CDS             complement(2695..3501)
                     /locus_tag="VV588_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU7084262.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3708..4349)
                     /locus_tag="VV588_001986"
     CDS             complement(3708..4349)
                     /locus_tag="VV588_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084263.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4346..6454)
                     /locus_tag="VV588_001987"
     CDS             complement(4346..6454)
                     /locus_tag="VV588_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU7084264.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6506..6793)
                     /locus_tag="VV588_001988"
     CDS             complement(6506..6793)
                     /locus_tag="VV588_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU7084265.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            7217..>7478
                     /locus_tag="VV588_001989"
     CDS             7217..>7478
                     /locus_tag="VV588_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU7084266.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICRDDAKLIQKGFSLLELTEET"
BASE COUNT         2386 a         1624 c         1160 g         2308 t
ORIGIN      
        1 ttatcagaat tgaaaacaga tatacgtctt tttgtatcac taaaacataa cctaaaaata
       61 tatagaccat caaatctagt acaaaaagag aaaatatcct ccttttcatt accttacttg
      121 ccttaaagat tctgtttaat agaaccttta tcgtagtatc tacacaaatt tttatcaaaa
      181 agataagagc caatacacct gctgctgcac caataagcca acctccaagg cctccaacct
      241 taatatagtt tattagtttt tttgttaaaa ctgcagctcc agtcaatgct ataaaagttc
      301 ctgggctcat agctaaagct gcgcaaattc cttgacaagc actcttgctt aaataagccc
      361 cccccatcaa gatacatcat ctcctcttgc tcaagagcaa cataattatt tggtaatacg
      421 agttccattt attttctcct ttatactatg taataccaca aaatgatttt gacctaaatc
      481 attcttaact tgaagaatcg caggaaatgt taattttgga gtcaaatctt ccagtgccac
      541 tcgaacagct tttactgtaa aattcaactt attcagacct gaaacaatac cactgacagt
      601 cgttccatac atgtctgtac caataatttc ccgaatcttc atgattgata gttccttttt
      661 gtaagataaa agaactgttg aaacaactgc cgcagcacaa tctgactgat catgttgcat
      721 cgtacaagga tattttttta acatagaaat actcaattct ttagaattaa tctaactttt
      781 ctttgatgtc acccaaacct caatcactgc ccagtagttc ttgaatcagt ttattttcaa
      841 tcgtatcatt ctttgttctt gatatctttc caagcattgt agtacagcag atttttgtcc
      901 aaggactgag cctcctttaa caactcaagc tcccttacat tatatcgacc agccccatgg
      961 aaagattatg accagactaa tcaatgatat catacatact agaatacaaa atattttttt
     1021 attcatactt tttctcctat ctttattttc tacctacatc atacctctta ttaagctcat
     1081 tttaaaatta cgttaacttt tttcacaaat ttatttcgac tttctttttt actttttaca
     1141 ttgctatgat acaatatttt taacaagatt ttattatttg ttaacttttt tcacagaaag
     1201 gagaaaatca tgcgttatga tttcggaaag gtctataaag aaatacgtga gtcaaagggg
     1261 ctgacccaag aagaggtctg tgggggtgtt ctctcaagaa ccagcttatc aaaaatcgaa
     1321 agtggcaaga caaccccaaa atatgaaaat atggaatttc ttctccgtca aatcaatatg
     1381 agttttgaag agtttgaata tatctgtcaa ctttatcaac caagtcaacg cacagagatt
     1441 atgcaaacct atctcaatat gcgttccatt atcgggacca gcgatcttgt caatttattt
     1501 caaaaatgcc aagactacct caagacccac cacgatctcc ctatagaaga aatcagagat
     1561 atgcttgaag ttgtcattta tatccgtcaa cacggggcag gggaactatc agatcacgca
     1621 gaacaggttg tcaaaaaact ttggagaaaa attgaaaaac aagatacatg gtatgagagt
     1681 gatctaaaaa tcctcaatac cattcttttc agttttccca ttgaatacct ccatctcatc
     1741 actggaaaaa tattgcaacg cctagaagtc tataaaaact atcaacattt atatgacttg
     1801 cgaatagcaa tcctgctcaa cctttccaca ctctatctat acaatcaaga taaaaacatg
     1861 tgtaagcaaa tctgctacac tttactggag gacgccaaga ataagaaaag ctacgatagg
     1921 ctggctatct gctatgtccg cattgggatt tgtacagacg attctaaact tatccaaaaa
     1981 ggtttctcac tcctagagct gaccgaggaa acttctatgc tgtctcatct caaaaaagaa
     2041 gtagagatct attaccaagc gaaggaaaga taaaaaagcc gagggagctc ctcgaccttt
     2101 tcatagaatc gccgaacgat ttaacgagaa agtatgactt ttacgtttat cccaactcaa
     2161 ttatgacatt tttttcaaaa gtcaatatat ctcacttttt caacgacaag aaagaggctg
     2221 ataatctacc aacctcttat tctgaaccca tcactccatc actttttagc ttcattcgct
     2281 ttcttagcga ctgcaatctg gtattcgact tggtcattcc ccttaccggt acaaccatga
     2341 gcaattgtag tcgctcctat ctgatgcgct atttcaacca attttttaga aatcagaggg
     2401 cggctcaagg cagataccaa gggatacttt tgttcataat aggcatgtga ctgaagagcc
     2461 actagcacat aatctgtagc aaattcgtcc ttaacatcaa tgacataaga ttctactgcc
     2521 ccaaccttaa gagccttatc atggatgaaa tctaagtctt tcccttcacc cacatccata
     2581 caaactgaaa caacatcata gtctttcttt aaccaggtaa tagcaactga tgtgtccaaa
     2641 ccgccagaat aggccaaaat tactttttct ttactcatgt tcttttcctt ctttctattt
     2701 ttcaatggat gctttaaagg catcctcaat gagtttgtct aattccccag actccttcaa
     2761 cttttgaatg gttttatcga ctgcctcttt caattccttg ctatcttttt tcatggctac
     2821 cgcgtaggaa tcatcttgct ctttttcaaa attgaggtct gcgattgcta aatcaggatt
     2881 attttccaca aatcccttgg aaacaggttc ttcaaagata acggcatcca cttgtcctga
     2941 ttttaaatct gtgattaaat tcccattttt aggcagagat acgagggaag aattttgtag
     3001 caaatctttc gccatcgtct cttgaatcga acctttctgc gctccaacct ttttctgcgc
     3061 caagtcgttt acagactgat aagtagtcaa gtcagatttt ttgacaatga gtttattttt
     3121 tgcagtatag tagggaatgg aaaagtcaaa caccttgctc cgttcatctg tcttagaaac
     3181 acctgatatg gcaaggtcgg cttttcctga ttgaacacta gccagtacat tatcaaaact
     3241 catgggagat agttccaatt cgacacctag ttctgttgcg atagccttgg ctaattcgat
     3301 atctgaaccc acaatctgat ttttcccatc aaccactttt tggtattcaa atggagcaaa
     3361 atccggattg agggctacaa ccaattttcc tttggacttg atggcttcaa ttccagccga
     3421 ttgattgttg ctacaagcaa atagtagggg gagcatcact aaaccaaaca tcgtcatcaa
     3481 caccttcttc atcttattca taataaagcc tactttatgt ttattccttt tgtttgtata
     3541 aacaatacat ctatattcat cctttgtcaa gcctaaattg aaaaaatttt caatttgaaa
     3601 caaaaaaaac ctagaaatac tacataaaat gtcattccta ggcgtattta tgctattttt
     3661 ctctggaaaa catgagtatt cagccagtca aaaggagctg aatgaactca ttttccctcg
     3721 cccaattcaa tgacacgatg acattgttgg gctacataag catcgtgggt cacaataatg
     3781 actgttttcc cttctcgatt catctctaag agaaacttca agaccaaatc tctattttca
     3841 ggatccagcg aacctgtagg ttcatcggct aaaatcagct ggctgggttt taagatggct
     3901 ctagcaactg caattcgttg ttgttcgcca ccagacaact cggagaccct ttgatgcaaa
     3961 gtagctgaca aacctactct ctctaaaatc tcttccacct ttttgagctt gtctttctta
     4021 ggcaatttca catatttcag cgccagcatg agattgtact cgaccgtttc atcatcaatc
     4081 agggcaaaat tttgaaacag ataagagata tgttcacgga ttattgtttg cgacttagca
     4141 gaattaaccg ctagatttgt ctgaccaaaa atctcatacc gtccgctata atcaccatct
     4201 atcaaaccca ataaatttaa caaggtcgac ttcccactac cactcttacc aacaatagct
     4261 accaaatccc cctgatcaat cctgagagat aagttatcca aaatcacttt tcccccaatg
     4321 gttttggtaa tatttttcaa ctcaatcata agatgccccc tttcaataac tctactagac
     4381 ttcttttctc catcctagaa gctaagccta gcacaaatag tatatccaga catgtaaaac
     4441 ctgcaaacag tagaagtggt aagaacgcat gggcaaagaa aatcaagact agaagaggga
     4501 aactatagcc cagcaagagc agaacgagga gaggacggta gcgatcgacc agtttccacc
     4561 ccataaactt cttggtaatg atatccctgc gcttcaataa gaaagttgtt actagtaaga
     4621 agtaggaaat catcatgcta aggagaccaa acaaagcaaa gagtaggtta aaattccgaa
     4681 cagcatctct ataagaatcc actttctctt gttgaatggc ttgaatagat gaaaatttta
     4741 aataatttcc atctgacaat ttctcaacta actctgtaat ctctttttga tgttgaaccg
     4801 tattttcaat tttaatcgga ttatttaagc cagttgttga cagggaggct ttctcatccc
     4861 acatcatatc agaatcattg accaagctaa taattggatt ggagagattt tcctttcgct
     4921 tatcactata tgggaaaaat gaccaatctc cttcataata ggcaatctcg acatccatct
     4981 cctctatcgt tcgtttttgc tgctcttcat acttcatcga atgaaaggca attaacttcc
     5041 ccaagagctg atttttatct tcttcacctt tcgtacttgc tggcatcaaa ataacttttt
     5101 taataccggt atctggtagc ttgaatccct tgctctttag aaaattgcga ttggcatagt
     5161 aaacatccac cgtatctgtt aactgatatt gctgaatctg ttctgattgg acaaaatttt
     5221 ttacaggaag actgctactc tgcacatagc ccgcctgcgt tttttctacc aaatcctgat
     5281 aaaatcgata gaaataatct gtagatttcc ctgaccctgc tagctcttct tgccacagat
     5341 tatcattgag tttgaaggtt tctaaggtca ggtaattacc ttgacttacc cactgttgct
     5401 gataagcaag ttctttgttt tcttgttcta aacttctgcc caccccaatc agtaaggccg
     5461 tcagtaaaat agttgtccct attttcatca cataattgaa gataagacca aatttgaaag
     5521 atgaaaaacc tttcagcaga gagctgattg tcattttttg gattaagagg taagtcaacc
     5581 aactgataaa gagataaagc tgcaacagca aaaaatgaga caaccacagc ataggaaaca
     5641 aatcttttgg cttataatca agcaagaaaa acacgcctag attgatcaca agagccccac
     5701 ctaggaggag gtaaaggttg ccttttacaa catcagctaa aacagcccta tcttgaaaac
     5761 caagtaattt ttgtacccca actcttttca tctccatcat cggttgatac actgtcacta
     5821 acacaagaag caaaatagcc aagacaaaaa caatggcaga taaaagcaaa tctcgattta
     5881 tgacttccac tgcacttttg taggtcggct ctagcaaggt agcctggtct atcttgaaaa
     5941 aatcgctcca tttctgtaca atcctatcct tgtccatctc ttgtgtagaa gttatcgtat
     6001 agcgaccatt taaactacga gatgtatcct tgatataggt ttgaaaagtc ataagctgaa
     6061 taggtttggc ttttagaaag gtcggaatcg taccaagttt attggaaatt tctttattac
     6121 tatagactcc ttcaccatct gtggtaaaat caagagaaga aatcccaaac tcttggtagg
     6181 ggaaggtatc tttatcaaaa acaccagact tgaccacctc atcaccactg tctgttttga
     6241 tgatggagac tttatactcc tttgatacat cctcaaaaaa tcgaagaaca gacgctgcag
     6301 gttcgttaat atctttcaaa tacaaatcca aagaatctac agtctttccc atttcttgaa
     6361 tccgaaccac ttctcgtgta tagtttacat taaaaacaaa aaaagtggta cacagaagca
     6421 ggagtaacat acagaaatta ctgatttttt tcataaaagt gcctccacta cagttttccc
     6481 tctccaaata ggagagggaa gaattttact caaatccata gaaatattcc attcctgttg
     6541 gcggaatctt ggtgagggaa gctctagccc atgcctcagg ttttgcataa tccttagagg
     6601 ttctaccccc atgtctaaca gttgctgtat gatatcgagt agaatgtaag taatcagaat
     6661 atccaaaagt tcctgtccaa cctactccat agttccattg accaccctca acccatactg
     6721 ctaaagcatt tgtagtagca agtataccac ataccattaa agatgcaaca ccaattttaa
     6781 ctaattttct catgatttat ttctcctatt atcgagagct gttccgtaaa aacagctata
     6841 gtaatttatc aacaagtatc gtagtccatt ggactcacct tccttctatc tcatttcatt
     6901 tttaacaacg aacttactct taaccgggag aatggtgcgc ttctgtatca ggtccttgaa
     6961 caaccagagt agtattaagc acactctaac tattactcaa gaatcagtcc aataaacaat
     7021 atggatagcg ctttcaaatt tttaaactcc tatcccatcc ttttatctat ataataagtg
     7081 aaaatataat aactgtcaag taactgaagt gaattttata aaaaaattac aagccaaatt
     7141 tgtaaagttt acactaagcc gctagggcaa tcgtctatca gaatatccgt ttatttgtca
     7201 ataatccgag aaaatcttgc aacgcttaga agtctataaa aactatcaac atttatatga
     7261 cttgcgaata gcaatcctgc taaacctttc cacactctat ctatacaatc aagataaaaa
     7321 catgtgtaag caaatctgct acactttact ggaggacgcc aagaataaga aaagctacga
     7381 taggctggct atctgctatg tccctattgg gatttgtagg gatgatgcga aacttatcca
     7441 aaaaggtttc tcactcctag agctaaccga ggaaactt
//
LOCUS       DAVIME010000072         7150 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVIME010000072 DAVIME010000000
VERSION     DAVIME010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.072"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            311..6745
                     /locus_tag="VV588_001990"
     CDS             311..6745
                     /locus_tag="VV588_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU7084267.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKE
                     ENSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKGLSNLKNTKVLYT
                     YDRIFNGSAIETTPDNLDKIKQIEGISSIERAQKVQPMMNHARKEIGVEEAIDYLKSI
                     NAPFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDK
                     IPHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNA
                     QIFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRA
                     LRKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQ
                     TVEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLD
                     LRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEG
                     TKSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNV
                     GDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVI
                     NGKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIAL
                     QNTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYG
                     SISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDG
                     KQIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFES
                     VEEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDG
                     KPKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSS
                     GSKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVI
                     SREHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPAT
                     KIRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLI
                     TKDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTY
                     AGEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADQADEK
                     GMISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEG
                     EASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKRNIIA
                     YDDGSALQYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2812 a          972 c         1370 g         1996 t
ORIGIN      
        1 cgtcagttcc atctacaacc tcaaaacagt gttttgagca acctgcggct agtttcctag
       61 tttgctcttt gattttcatt gagtactaat cttatttttt aacatgtgct aaaaaataaa
      121 ttaatgcatg ttaatttttt tgacttaaat ttttttaaat gatatactgt ttttatagag
      181 agataacaat tatatataaa tgtactactc tatttcctag ataatactta gtaaaacttt
      241 ttataacaaa ggctagcaaa gttaaagttt attatctatt ggaagttaaa taaatatgta
      301 aggaattaaa atgaaaaaaa gcacagtatt gtcattaact acagctgcag ttattttagc
      361 agcctatgcc cctaatgagg tagtcttagc agacacatct agctctgaag atgctttaag
      421 catctctgat aaagaaaaag tagtagtaga taaggaaaca gaaaataaag agaaacataa
      481 agatattcat aatgctatag aaacttcaaa ggatactgaa gaaaagaaaa caacaattat
      541 tgaggaaaaa gaagttgtta gtaaaaatcc tgtaatagac actaaaacta gcaatgaaga
      601 agcaaaaatc aaagaagaaa attccaatca atcccaagga gatcatacgg actcatttgt
      661 gaataaaaac acagaaaatc ccaaaaaaga agataaagtt gtctatattg ctgaatttaa
      721 agataaagaa tctggagaaa aagcaatcaa gggactatca aatcttaaga atacaaaagt
      781 tttatatact tatgatagaa tttttaacgg tagtgccata gaaacaactc cagataactt
      841 ggacaaaatt aaacaaatag aaggtatttc atcgattgaa agggcacaaa aagtccaacc
      901 catgatgaat catgccagaa aggaaattgg agttgaggaa gctattgatt acctaaagtc
      961 tatcaatgct ccgtttggga aaaattttga tggtagaggt atggtcattt caaatatcga
     1021 tactggaaca gattatagac ataaggctat gagaatcgat gatgatgcca aagcctcaat
     1081 gagatttaaa aaagaagact taaaaggaac tgataaaaat tattggttga gtgataaaat
     1141 ccctcatgcg ttcaattatt ataatggtgg caaaatcact gtagaaaaat atgatgatgg
     1201 aagggattat tttgacccac atgggatgca tattgcaggg attcttgctg gaaatgatac
     1261 tgaacaagat atcaaaaact ttaacggcat agatggaatt gcacctaatg cacaaatttt
     1321 ctcttacaaa atgtattctg acgcaggatc tgggtttgcg ggtgatgaaa caatgtttca
     1381 tgctattgaa gattctatca aacacaacgt tgatgttgtt tcggtatcat ctggttttac
     1441 aggaacaggt cttgtaggtg agaaatattg gcaagctatt cgggcattaa gaaaagcagg
     1501 cattccaatg gttgtcgcta cgggtaacta tgcgacttct gcttcaagtt cttcatggga
     1561 tttagtagca aataatcatc tgaaaatgac cgacactgga aatgtaacac gaactgcagc
     1621 acatgaggat gcgatagcgg tcgcttctgc taaaaatcaa acagttgagt ttgataaagt
     1681 taacataggt ggagaaagtt ttaaatacag aaatataggg gcctttttcg ataagaataa
     1741 aatcacaaca aatgaagatg gaacaaaagc tcctagtaaa ttaaaatttg tatatatagg
     1801 caaggggcaa gaccaagatt tgataggttt ggatcttagg ggcaaaattg cagtaatgga
     1861 tagaatttat acaaaggatt taaaaaatgc ttttaaaaaa gctatggata agggtgcacg
     1921 cgccattatg gttgtaaata ctgtaaatta ctacaataga gataattgga cagagcttcc
     1981 agctatggga tatgaagcgg atgaaggtac taaaagtcaa gtgttttcaa tttcaggaga
     2041 tgatggtgta aagctatgga acatgattaa tcctgataaa aaaactgaag tcaaaagaaa
     2101 taataaagaa gattttaaag ataaattgga gcaatactat ccaattgata tggaaagttt
     2161 taattccaac aaaccgaatg taggtgacga aaaagagatt gactttaagt ttgcacctga
     2221 cacagacaaa gaactctata aagaagatat catcgttcca gcaggatcca catcttgggg
     2281 gccaagaata gatttacttt taaaacccga tgtttcagca cctggtaaaa atattaaatc
     2341 tacgcttaat gttattaatg gcaaatcaac ttatggctat atgtcaggaa ctagtatggc
     2401 gactccaatc gtggcagctt ctactgtttt gattagaccg aaattaaagg aaatgcttga
     2461 aagacctgta ttgaaaaatc ttaagggaga tgacaaaata gatcttacaa gtcttacaaa
     2521 aattgcccta caaaatactg ctcgacctat gatggatgca acttcttgga aagaaaaaag
     2581 tcaatacttt gcatcaccta gacaacaggg agcaggccta attaatgtgg ccaatgcttt
     2641 gagaaatgaa gttgtagcaa ctttcaaaaa cactgattct aaaggtttgg taaactcata
     2701 tggttccatt tctcttaaag aaataaaagg tgataaaaaa tactttacaa tcaagcttca
     2761 caatacatca aacagacctt tgacttttaa agtttcagca tcagcgataa ctacagattc
     2821 tctaactgac agattaaaac ttgatgaaac atataaagat gaaaaatctc cagatggtaa
     2881 gcaaattgtt ccagaaattc acccagaaaa agtcaaagga gcaaatatca catttgagca
     2941 tgatactttc actataggcg caaattctag ctttgatttg aatgcggtta taaatgttgg
     3001 agaggccaaa aacaaaaata aatttgtaga atcatttatt cattttgagt cagtggaaga
     3061 aatggaagct ctaaactcca acgggaagaa aataaacttc caaccttctt tgtcgatgcc
     3121 tctaatggga tttgctggga attggaacca cgaaccaatc cttgataaat gggcttggga
     3181 agaagggtca agatcaaaaa cactgggagg ttatgatgat gatggtaaac cgaaaattcc
     3241 aggaacctta aataagggaa ttggtggaga acatggtata gataaattta atccagcagg
     3301 agttatacaa aatagaaaag ataaaaatac aacatccctg gatcaaaatc cagaattatt
     3361 tgctttcaat aaccaaggga tcaacgctcc atcatcaagt ggttctaaga ttgctaacat
     3421 ttatccttta gattcaaatg gaaatcctca agatgctcaa cttgaaagag gattaacacc
     3481 ttctccactt gtattaagaa gtgcagaaga aggattgatt tcaatagtaa atacaaataa
     3541 agagggagaa aatcaaagag acttaaaagt catttcgaga gaacacttta ttagaggaat
     3601 tttaaattct aaaagcaatg atgcaaaggg aatcaaatca tctaaactaa aagtttgggg
     3661 tgacttgaag tgggatggac tcatctataa tcctagaggt agagaagaaa atgcaccaga
     3721 aagtaaggat aatcaagatc ctgctactaa gataagaggt caatttgaac cgattgcgga
     3781 aggtcaatat ttctataaat ttaaatatag attaactaaa gattacccat ggcaggtttc
     3841 ctatattcct gtaaaaattg ataacaccgc ccctaagatt gtttcggttg atttttcaaa
     3901 tcctgaaaaa attaagttga ttacaaagga tacttatcat aaggtaaaag atcagtataa
     3961 gaatgaaacg ctatttgcga gagatcaaaa agaacatcct gaaaaatttg acgagattgc
     4021 gaacgaagtt tggtatgctg gcgccgctct tgttaatgaa gatggagagg ttgaaaaaaa
     4081 tcttgaagta acttacgcag gtgagggtca aggaagaaat agaaaacttg acaaagacgg
     4141 aaataccatt tatgaaatta aaggtgcagg agatttaaga ggaaaaatca ttgaagtcat
     4201 tgcattagat ggttctagca atttcacaaa gattcataga attaaatttg ctgatcaggc
     4261 tgatgaaaag gggatgattt cttattacct agtagatcct gacaaagatg cttctaaata
     4321 tgaaaaactt ggtgaaattt ctgaagataa actcaaaaat gcaaagagcc cagaggaaaa
     4381 taccaataat aatcaagcta aggatgaaga ttcaaaacca gatgaaaaaa gttcagttga
     4441 gggagaagct agccttgaaa taaataaaac tatttcaaca attagagagt ttgaaaataa
     4501 agacctaaag aaactcatta aaaagaaatt tagagaagtt gatgatttta caagtgaaac
     4561 tggtaagaga atagaggaat acgattataa atacgatgat aagagaaata ttattgctta
     4621 tgacgatggt agtgccttac aatatgaaac tgaaaaattt gacgaaataa aatcaaaaat
     4681 ttatggtgtt ctaagcccat ctaaagatgg acactttgaa attcttggaa agataagcaa
     4741 tgtttctaaa aatgccaagg tatattatgg aaatagctat aaatcgatag aaatcaaagc
     4801 gactaagtat gattcacatt caaaaacgat gatatttgat ttatacgcta atattaatga
     4861 tattgtagat ggattagctt ttgctggaga tatgagatta tttgttaaag atgacaatca
     4921 aataaaagct gaaactaaga ttagaatgcc tgaaaaaaat aaggaaacta aagcagaata
     4981 tccctatgta tcaagttatg ggaatgtaat cgaattagga gaaggagatc tttcaaagaa
     5041 caaaccagac aatttaacta aaatggaatc tggtaaaatc tattctgatt cagaaaaaca
     5101 acaatatctg ttaaaggata acatcattct aagaaaaggc tatgcactaa aagtgactac
     5161 ctataatcct ggaaaaacgg atatgttaga aggaaatgga gtctatagca aggaagatat
     5221 agcaaaaata caaaaggcca atcctaatct aagagtcctt tcagaaacaa caatttatgc
     5281 tgatagtaga aatgttgaag atggaagaag tacccaagct gtattaatgt cggctttgga
     5341 cggctttaac attataaggt atcaagtgtt tacatttaaa atgaacgata aaggggaagc
     5401 tatcgataaa gacggaaatc ttgtgacaga ttcttctaaa cttgtattat ttggtaagga
     5461 tgataaagaa tacactggag aggataagtc caatgtagaa gctataaaag aagatggctc
     5521 catgttattt attgatacca aaccagtaaa cctttcaatg gataagaact actttaatcc
     5581 atctaaatct aataaaattt atgtacgaaa tccagaattt tatttaagag gtaagatttc
     5641 tgataagggt ggttttaact gggaattgag agttaatgaa tcggttgtag ataattattt
     5701 aatctacgga gatttacaca ttgataacac tagagatttt aatattaagc tgaatgttaa
     5761 agacggtgac atcatggact ggggaatgaa agactataaa gcaaacggat ttccagataa
     5821 ggtaacagat atggatggaa atgtttatct tcaaactggc tatagcgatt tgaatgctaa
     5881 agcagttgga gtccactatc agtttttata tgataatgtt aaacctgaag taaacattga
     5941 tcctaaggga aatactagta tcgaatatgc tgatggaaaa tctgtagtct ttaacatcaa
     6001 tgataaaaga aataatggat tcgatggtga gattcaagaa caacatattt atgtaaatgg
     6061 aaaagaatat acatcatttg atgatattaa acaaataaca gacaagacac taaacattaa
     6121 gattgttgta aaagattttg caagaaatac aaccgtaaaa gaattcattt taaataaaga
     6181 tacgggagag gtaagtgaat taaaacctca tagggtaact gtgaccattc aaaatggaaa
     6241 agaaatgagt tcaacgatag tgtcggaaga agattttatt ttacctgttt ataagggtga
     6301 attagaaaaa ggataccaat ttgatggttg ggaaatttct ggtttcgaag gtaaaaaaga
     6361 cgctggctat gttattaatc tatcaaaaga tacctttata aaacctgtat tcaagaaaat
     6421 agaggagaaa aaggaggaag agaataaacc tacttttgat gtatcgaaaa agaaagataa
     6481 cccacaagta aatcatagtc aattaaatga aagtcacaga aaagaggatt tacaaagaga
     6541 agatcattca caaaaatctg attcaactaa ggatgttaca gctacagttc ttgataaaaa
     6601 caatatcagt agtaaatcaa ctactaacaa tcctaataag ttgccaaaaa ctggaacagc
     6661 aagcggagcc cagacactat tagctgccgg aataatgttt atagtaggaa tttttcttgg
     6721 attgaagaaa aaaaatcaag attaagacaa aagctataga aaaaaatggt ttatgtactg
     6781 agattagata gtgaggtgat gacatagttt tgtgaaaaca gccatttata actcaattat
     6841 ttagtttact tcactattga tactatttgg agttattaat ggacttagtt tagataacta
     6901 atgaattgat tgaaagggtt agtattgaca atattggtca tattgattag aaaatagagt
     6961 ctatcaaaat ttaaaggcta atagaggtga tgagacaatt tcaaggaatt aagtagcgtt
     7021 tggttgctta attccttttt atttggaagg aagtttttcg taaccgccca ataacgaagt
     7081 ctattggacg gttacgatat gatcactgac ttcgtcagtc ttatctacaa cctcaaaact
     7141 gtgttttgag
//
LOCUS       DAVIME010000073         7074 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVIME010000073 DAVIME010000000
VERSION     DAVIME010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.073"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..372
                     /locus_tag="VV588_001991"
     CDS             <1..372
                     /locus_tag="VV588_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU7084268.1"
                     /translation="KVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQNFL
                     LPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHL
                     KKVLPSCNTFYEALLSCSCFN"
     gene            433..1395
                     /locus_tag="VV588_001992"
     CDS             433..1395
                     /locus_tag="VV588_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU7084269.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYEDTSISVSSNETDKV
                     LAGSLYTDTNEQGLMIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1572..2579
                     /gene="gap"
                     /locus_tag="VV588_001993"
     CDS             1572..2579
                     /gene="gap"
                     /locus_tag="VV588_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU7084270.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2647..3483)
                     /locus_tag="VV588_001994"
     CDS             complement(2647..3483)
                     /locus_tag="VV588_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU7084271.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVRWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3609..5804
                     /locus_tag="VV588_001995"
     CDS             3609..5804
                     /locus_tag="VV588_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU7084272.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5857..6009
                     /gene="rpmG"
                     /locus_tag="VV588_001996"
     CDS             5857..6009
                     /gene="rpmG"
                     /locus_tag="VV588_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU7084273.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6019..6195
                     /gene="secE"
                     /locus_tag="VV588_001997"
     CDS             6019..6195
                     /gene="secE"
                     /locus_tag="VV588_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU7084274.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6250..6786
                     /gene="nusG"
                     /locus_tag="VV588_001998"
     CDS             6250..6786
                     /gene="nusG"
                     /locus_tag="VV588_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU7084275.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6908..>7074
                     /locus_tag="VV588_001999"
     CDS             6908..>7074
                     /locus_tag="VV588_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084276.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRL"
BASE COUNT         2202 a         1226 c         1544 g         2102 t
ORIGIN      
        1 aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac aaatggtgaa
       61 ttaatcgctc caatgactta cgaagagacg atgacgagcg acttttttga agcttggttt
      121 cagaattttc tcttaccaac attaaccaca ccatcggtta ttattatgga taatgtaaga
      181 ttccatagaa tggggaagct agaactttta tgcgaagagt ttgggcataa actgttacct
      241 cttcctccct actcgcctga gtacaatcct attgagaaaa catgggctca tatcaaaaag
      301 cacctcaaaa aggtattacc aagttgcaat accttttacg aggctctttt gtcttgttct
      361 tgtttcaatt gactatagtt cacggataca gttgggaaag aagctattaa ttatttggag
      421 agtccttttg ggatgaacat gtcaaatatt actatagatg ggcaagaaat ggatctgagt
      481 caaacgatgc cttcttatgc tcaagtagtg agtctttatg aggatacaag catctctgtt
      541 agtagtaatg agacggacaa agtgttggct ggatccctct atactgatac aaatgaacag
      601 ggattaatga ttccaagcag tttactaaaa aattggaatg aacagacagg aaaaaatttg
      661 acagctaatg atcttattgg caaatcagtc tcagccagca ttgtagaaag tgctgccgaa
      721 gctagtaaga ttgctcaatt tcaaacgaag attgtacgtg taatcaatga tgaagatgac
      781 atggaggaca gcaacagttt catgctgtct catcaaatgg aaacgatttt gaaagaggct
      841 ggatttacga aagctgtatc ttattttatc ttggaactca aagatccatc acagacaaaa
      901 gtagtaacag aagaattaca gaaaaataag aagtatactg tgctttctca acagagagtt
      961 cttgatattg tgattacctt tattcgtgtt attcagggat tattgattgt gctttcatca
     1021 caagctattg tggtagcagc ggttatgatt ggtatcatta tttacatcaa tatcatgcaa
     1081 cgttccaagg aaataggtgt catgaaagca gttggttatc agaatcgtgg tgtcaaagga
     1141 atttttattt acgaggctat ctggattgta ggcatcgcct tgctgctggc atttttggtt
     1201 gcacaagggg tgggaagttt ggcgaatgcg attgtaagtc acttttaccc atccatcact
     1261 aaggtttttg aattaaatct tttatctgtt ttaggaactc tagttttcgc tctattactt
     1321 ggttatgtct cagcctactt cccggcgcgt aagattagta aaatggatcc tgtagaatcg
     1381 ttacgctatg aataataagg gattccttga tttacagtct taaaaagaaa ctcacataga
     1441 aaaacaatgg ccatacttgc aattcaactc aaatagttgt ataataggtt tgttgaaagg
     1501 tgatttgtag tgattcaagt tactcttttc acaataaaaa tttcatgatt ttcataagga
     1561 ggaaatcact aatggtagtt aaagttggta ttaacggttt cggacgtatc ggtcgtcttg
     1621 ctttccgtcg tatccaaaac gtagaaggtg ttgaagttac acgcatcaac gaccttacag
     1681 atccagttat gcttgcacac ttgttgaaat acgacacaac tcaaggtcgt ttcgacggta
     1741 ctgttgaagt taaagaaggt ggatttgaag ttaacggtaa attcatcaaa gtttctgctg
     1801 aacgtgatcc agaacaaatc gactgggcta ctgacggtgt agaaatcgtt cttgaagcta
     1861 ctggtttctt tgctaagaaa gaagcagctg aaaaacacct taaaggtgga gctaaaaaag
     1921 ttgttatcac tgctcctggt ggaaacgacg ttaaaacagt tgtattcaac actaaccacg
     1981 acgttcttga cggtactgaa acagttatct caggtgcttc atgtactaca aactgcttgg
     2041 ctccaatggc taaagctctt caagacaact ttggtgttgt tgaaggattg atgactacta
     2101 tccacgctta cactggtgac caaatgatcc ttgacggacc acaccgtggt ggtgaccttc
     2161 gccgtgctcg cgctggtgct gcaaacatcg ttcctaactc aactggtgct gcaaaagcta
     2221 tcggtcttgt aatcccagaa ttgaatggta aacttgatgg atctgcacaa cgcgttccaa
     2281 ctccaactgg atcagttact gaattggtag cagttcttga aaagaacgtt actgttgatg
     2341 aagtgaacgc agctatgaaa gcagcttcaa acgaatcata cggttacaca gaagatccaa
     2401 tcgtatcttc agatatcgta ggtatgtctt acggttcatt atttgacgca actcaaacta
     2461 aagttcttga cgttgacggt aaacaattgg ttaaagttgt atcatggtac gacaacgaaa
     2521 tgtcatacac tgcacaactt gttcgtactc ttgaatactt cgcaaagatt gctaaataat
     2581 tcttgagttg atagaaagca aggctttgtg gtcttgcttt tttatatgga aaaatggatg
     2641 acacgatcat ccattctttt ttaattcttt ttcaaatgta tttgaaaggg tagtgaaagt
     2701 tagcctctct aaagtaagtg ggtgggtaaa ggaaagtcgg aaggcatgaa gcataagccg
     2761 gcttgtcttt gatttactat tatagagagg gtctcccagg ataggaagat tatgatgcaa
     2821 aaggtgcaca cgaatctgat gggttcgccc tgtctttagc ttgcaatgag ccaaggaagt
     2881 cttgtttgag aattgcttta atctgcttac atgcgtttca gcatattgcc cattttttgc
     2941 atcaactatt ctttttctac gatcatggcg atcacgtcca attttgtctc tgaaaacaag
     3001 ttcttttctg ttgatatttc catcaactag agcccaatat tctctagaaa tctctttttt
     3061 ctccaataag cgattgagaa tgggcaggat aaaaggattt ttggcaaaga gaactaagcc
     3121 actggtttcc atgtccagac gatgaacgac atagcaggtt tggccaacat aggtactgac
     3181 atggttaaga agggcaattt cgtttggttg attaccatgc gttttcatcc cctctggttt
     3241 gtttacaata atcaagtgtt gatcttgata aacttcctgc actaagtctg ggttgcccca
     3301 agggatcgtc ttttggggat aatcttcctc gtcaaaagtc aactggcaaa catctccagg
     3361 atttacgatt tcgttccagc ggacttcttc ttgatttatc aaaatatgtt tcttgattct
     3421 caaaaaatga cggatttttc tagggatgag gagttgttcc tcaagtaatt gctttaccgt
     3481 catttgaggt agagaggcgg gtaatgtaaa tgtgaattgc atacagatat tgtaacaaaa
     3541 aaagccctat ttggatagga aatagctaaa ttcttgtctt cctatgatga agatgataaa
     3601 ataaacgcat gaaattagat aaattatttg agaaatttct ttctcttttt aaaaaagaaa
     3661 caagtgaact agaggactct gattctacta tcttacgtcg ctctcgtagt gatcgaaaaa
     3721 aattagccca agtaggtccg attcgaaaat tctggcgtcg ttatcatcta acaaagatta
     3781 tccttatact aggtttgagt gcaggcttgc tagttggaat ctatttgttt gctgtagcca
     3841 agtcgaccaa tgtcaatgat ttgcaaaatg ccttgaaaac tcggactctt atttttgacc
     3901 gtgaagaaaa agaggctggt gccttgtctg gtcaaaaggg aacctatgtt gagctgactg
     3961 acatcagtaa aaacttgcag aatgctgtta ttgcgacaga agaccgttct ttctataaaa
     4021 atgacgggat taactatggc cgtttcttct tggctattgt cactgctgga cgttcaggtg
     4081 gtggctctac cattacccaa cagctggcta aaaacgccta tttatcgcag gatcaaactg
     4141 ttgagagaaa agcgaaagaa tttttccttg ccttagaatt aagcaaaaaa tatagtaagg
     4201 agcaaattct aaccatgtac cttaacaacg cttattttgg aaatggtgtg tggggtgtag
     4261 aagatgcgag taagaaatac tttggagttt ctgcatcaga agtgagtctg gatcaagctg
     4321 cgactctggc agggatgctc aaggggccgg aactgtataa tcccttgaat tccgtagaag
     4381 attctactaa tcggcgcgat actgtcttgc agaatatggt tgcagcagga tatattgata
     4441 aaaaccaaga aaccgaagct gctgaagttg atatgacttc gcaattgcac gataagtatg
     4501 aaggaaaaat ctcagattac cgttacccct cttattttga tgcggtggtt aatgaagctg
     4561 tttccaagta taatctaaca gaggaagaga ttgtcaataa tggctaccgc atttacacag
     4621 agctggacca aaactaccaa gcaaatatgc agattgttta tgaaaacaca tcgctatttc
     4681 cgagggcaga ggatggaacg tttgctcaat caggaagtgt agctctcgaa ccgaaaacag
     4741 ggggagttcg tggagttgtc ggtcaagttg ctgacaatga taaaactgga ttccggaatt
     4801 tcaactatgc aacccaatca aagcgtagtc ctggttctac aattaagcct ttagttgttt
     4861 atacgccagc agttgaagca ggctgggctt tgaataagca gttggataac cataccatgc
     4921 agtatgacag ctataaggtt gataactatg cagggatcaa aacgagtcga gaagttccta
     4981 tgtatcaagc cttggcagaa tcgcttaatc tacctgctgt tgccactgtt aatgatttgg
     5041 gtgtcgacaa ggcttttgag gcaggcgaaa aattcggact caacatggaa aaggtcgacc
     5101 gtgttcttgg tgtcgccttg ggaagcggtg ttgaaaccaa ccctcttcaa atggctcaag
     5161 catacgctgc ctttgcaaat gaaggtttaa tgcctgaagc tcattttatt agtagaattg
     5221 aaaatgctag tggacaagtt attgcgaatc ataaaaattc acaaaaacgg gtgattgata
     5281 agtctgtagc tgacaagatg accagtatga tgttggggac tttcaccaac ggtaccggta
     5341 ttagttcatc gcctgcagac tatgtcatgg cagggaaaac tggaacaact gaagcagttt
     5401 tcaatccgga gtacacaagt gaccagtggg taattggtta tactccggat gtagtgatta
     5461 gccactggct tggctttccg accactgatg aaaatcacta tctagctggc tctacttcaa
     5521 acggtgcagc tcatgtcttt agaaacattg ccaataccat tttaccttat acgccaggaa
     5581 gtacctttac ggttgaaaat gcttataagc aaaatggaat tgcaccagcc aatacaaaaa
     5641 gacaagtaca aaccaatgat aatagccaga cagatgataa tttgtctgat attcgagggc
     5701 gtgcgcaaag tctagtagat gaggctagcc gggctatctc agatgcgaag attaaggaaa
     5761 aggctcaaac aatatgggat tcgatagtca atctatttcg ctaagatgct tgtcaaagcc
     5821 tagctttctt gttataatgg ataagatgga ggcgttatgg cactaaaaaa agcaagccta
     5881 gcttgtgcgg tttgtggttc gagaaactat tcaatcaaga tcagcggaaa ccccaagcct
     5941 acacgactag aagtaaataa attttgtaag cattgtggca agtacactac acacagagaa
     6001 acgagatagg agagagcgat gcgttttatt ggagatattt ttagacttct taaagacaca
     6061 acatggccaa ctcgcaagga aagctggaga gattttcgtt ctatcatgga atacacagct
     6121 ttctttgtag taattattta catttttgac cagttgattg tttcaggttt gattcgattt
     6181 attaacattt tttagaagat tagtggagtt aattacacta gaaatcttct atttatgaaa
     6241 ggaaatatca tggatagttt tgataaagga tggtttgttt tacaaactta ttctggttat
     6301 gaaaataagg tgaaagaaaa tctattacaa cgtgcacaaa cctacaatat gttggataat
     6361 attctacgcg ttgaaattcc aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa
     6421 gaagtagaag aaaatcgctt tccaggttat gttcttgtag aaatggtcat gacagatgaa
     6481 gcttggtttg ttgttcgaaa cacaccaaat gttacaggat ttgtcggatc acacgggaac
     6541 agatcaaaac caactccatt attggaacaa gaaattcgtg acattttggt atctatggga
     6601 caaactgttc aagaatttga tttcgatgtt gagattggtc aaactgtacg tattattgat
     6661 ggtgcttttg cagactacac tggtaagatt acagaaattg ataataacaa agtgaaaatg
     6721 attatctcta tgtttggtaa tgacacagtt gcagaagtaa acctaaacca aatcgcagaa
     6781 ttataaccct gagagaggct ggagcctctc ttttttgtgc agtttaggag ctaaagggaa
     6841 cagaatggag aaaatggaac aaatgtgttt tctaatctgt tagactgtat ctagaaaggg
     6901 gaaaattatg attaaagaat tgtatgaaga agtccaaggg actgtgtata agtgtagaaa
     6961 tgaatattac cttcatttat gggaattatc ggattgggac caagaaggca tgctctgctt
     7021 acatgaattg attagtagag aagaaggact ggtagacgat attccacgtt taag
//
LOCUS       DAVIME010000074         7039 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVIME010000074 DAVIME010000000
VERSION     DAVIME010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7039
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.074"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            14..403
                     /locus_tag="VV588_002000"
     CDS             14..403
                     /locus_tag="VV588_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084277.1"
                     /translation="MQIFTYNDFLKDKEIVTFEQAEIILDELIKSSNIYDPEFQAYWK
                     ELIEYSAKYAEMRGKWRILTKEEQDTLDDTRTNIHNRIRDNLISIRGLAQINNKDTSW
                     FDKFHNDRKRMGDFANYINYIYAVNSR"
     gene            422..1192
                     /locus_tag="VV588_002001"
     CDS             422..1192
                     /locus_tag="VV588_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU7084278.1"
                     /translation="MAIYYSVSDIHGHYNEFIKSLNKIDLSDKQSKLILLGDYIDYGS
                     QSFQVISKIIELEKIYPKQIITLFGNHEEWFYDWLILDNPTASAFPETIKSFFSTEEL
                     NYILKTNPNNFETGVRNEIRNNDKYIPFINWFQKRYEDSRYFETENQIFVHAGIDEEA
                     NNLWKDLTSPEIFTNKFPITTGRFYKDIISGHFASWEVAKDKSYLGKIYHDSKSHYFI
                     DGDVKNSKTIPVICYDTVKKSYQYSKNTSLLPKKFDRA"
     gene            1236..2009
                     /locus_tag="VV588_002002"
     CDS             1236..2009
                     /locus_tag="VV588_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU7084279.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAV
                     KELLQDLKLQIAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEYEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHLEIISTNWATDETLKQLSKPQI"
     gene            2193..2975
                     /locus_tag="VV588_002003"
     CDS             2193..2975
                     /locus_tag="VV588_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEU7084280.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDSLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVWINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKYGQYFDNHVKYKKIRLDE"
     gene            2989..3192
                     /locus_tag="VV588_002004"
     CDS             2989..3192
                     /locus_tag="VV588_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HEU7084281.1"
                     /translation="MIATVTKNDLIALGFFEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLVFDVQNSTLKE"
     gene            3196..4329
                     /locus_tag="VV588_002005"
     CDS             3196..4329
                     /locus_tag="VV588_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU7084282.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITIPILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAETRRIVINKKLSQELQDWKKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            4370..4807
                     /locus_tag="VV588_002006"
     CDS             4370..4807
                     /locus_tag="VV588_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU7084283.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            5023..5259
                     /locus_tag="VV588_002007"
     CDS             5023..5259
                     /locus_tag="VV588_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEU7084284.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKATSHEEMMRRYG"
     gene            5252..5983
                     /locus_tag="VV588_002008"
     CDS             5252..5983
                     /locus_tag="VV588_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU7084285.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLYYDTITQKYHFL"
     gene            complement(6094..6177)
                     /locus_tag="VV588_002009"
     tRNA            complement(6094..6177)
                     /locus_tag="VV588_002009"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6141..6143),aa:Leu,seq:caa)
     gene            complement(6187..6258)
                     /locus_tag="VV588_002010"
     tRNA            complement(6187..6258)
                     /locus_tag="VV588_002010"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6224..6226),aa:Gln,seq:ttg)
     gene            complement(6269..6341)
                     /locus_tag="VV588_002011"
     tRNA            complement(6269..6341)
                     /locus_tag="VV588_002011"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6306..6308),aa:His,seq:gtg)
     gene            complement(6356..6426)
                     /locus_tag="VV588_002012"
     tRNA            complement(6356..6426)
                     /locus_tag="VV588_002012"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6392..6394),aa:Trp,seq:cca)
     gene            complement(6431..6511)
                     /locus_tag="VV588_002013"
     tRNA            complement(6431..6511)
                     /locus_tag="VV588_002013"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6475..6477),aa:Tyr,seq:gta)
     gene            complement(6524..6596)
                     /locus_tag="VV588_002014"
     tRNA            complement(6524..6596)
                     /locus_tag="VV588_002014"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6561..6563),aa:Phe,seq:gaa)
     gene            complement(6600..6673)
                     /locus_tag="VV588_002015"
     tRNA            complement(6600..6673)
                     /locus_tag="VV588_002015"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6637..6639),aa:Met,seq:cat)
     gene            complement(6684..6773)
                     /locus_tag="VV588_002016"
     tRNA            complement(6684..6773)
                     /locus_tag="VV588_002016"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6735..6737),aa:Ser,seq:tga)
     gene            complement(6857..6930)
                     /locus_tag="VV588_002017"
     tRNA            complement(6857..6930)
                     /locus_tag="VV588_002017"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6894..6896),aa:Ile,seq:gat)
     gene            complement(6965..7035)
                     /locus_tag="VV588_002018"
     tRNA            complement(6965..7035)
                     /locus_tag="VV588_002018"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7001..7003),aa:Gly,seq:tcc)
BASE COUNT         2620 a         1205 c         1197 g         2017 t
ORIGIN      
        1 aaaggagctt actatgcaaa tttttactta taacgatttt ctaaaagaca aagaaatcgt
       61 aacttttgaa caagctgaaa taattttaga tgaacttata aaatcatcaa acatttatga
      121 ccctgaattt caagcatact ggaaagaact tatcgagtac agtgcgaagt atgctgaaat
      181 gagaggaaaa tggcgaatac ttacaaaaga agagcaagat acacttgatg atacaagaac
      241 taatattcat aatagaatta gagataacct tatatctatt agaggcttgg ctcaaatcaa
      301 taacaaagat acctcttggt tcgataagtt tcataacgat agaaaacgta tgggtgattt
      361 tgctaattat ataaattaca tatacgctgt aaattcacgt tgattataga aagaatctta
      421 tatggcaatt tattattccg tatctgatat acatgggcac tacaatgagt ttattaaatc
      481 tctcaataaa atagatttat ctgataaaca aagtaaactt atcttacttg gagactatat
      541 tgattacggt tctcaatctt ttcaagtcat ttctaaaata attgaacttg aaaagattta
      601 tccaaaacaa attattacac tttttggaaa tcatgaagaa tggttttatg attggttgat
      661 tttagataat cctactgctt ctgcgtttcc agaaacaata aagagtttct tctctacaga
      721 ggaattgaac tatattttaa aaacaaatcc taacaacttt gaaacaggtg ttagaaacga
      781 aattagaaat aatgataagt atattccatt tataaactgg ttccaaaaac gatatgaaga
      841 tagtcgttat tttgaaacag aaaatcaaat ttttgtccat gctggcattg atgaagaagc
      901 taataatctt tggaaagacc taacgagtcc agagatattt accaacaaat ttcctattac
      961 aactggtaga ttttataaag atattatctc tgggcatttt gcttcttggg aagtagctaa
     1021 agataaaagt tacctaggta agatttacca tgatagtaaa agtcattact ttattgatgg
     1081 agatgtaaaa aatagcaaaa caatacctgt tatctgctat gatacagtta aaaaatccta
     1141 tcaatattca aaaaacactt ctctattgcc taaaaaattt gatagagctt aattctattc
     1201 ttagactaat atcaaaaata aagaggggaa tatatatgaa gacattatta attggtgact
     1261 tacatttaaa atctcaacta attttaccca ttgttgacaa aattatccaa acacataaca
     1321 ttaagagaat catttttctt ggtgattatg ttgatttaca tggtcaaact aacaatatcc
     1381 aactttatgc caaagacctc acttttttat actcttggaa aatagataaa gagcaaaacg
     1441 gaatagatgt aattaatctt ataggtaatc atgatgctta ttatttactg ggagaacaag
     1501 ctcctttctc aattcaaaat ttagaagtgt ttttcgcagt aaaagaattg ttgcaggatt
     1561 tgaaattaca aatagcttat caactagatg attatttagt cagtcacgct ggtttcaatc
     1621 tgatatttga cccaaaagaa tggcatttta acctttatac caaagagtat gaagaagaat
     1681 tagatatcct agcttataca ataggaccaa tgcgtggtgg gaaagctctt gggggttctc
     1741 ctttatgggc acattttaga gaattagaat tgcttcccaa ccaagacttt cctaaacaaa
     1801 ttgttggaca tacccctaaa gaatctattg atatttctaa aaatgttatt ggtatagata
     1861 ctttttcatt atatattgac aaagataata aatatcaatt tattggtaac ggagatttgc
     1921 tagtctatga ccaaggccat cttgaaatca tttcaaccaa ctgggctaca gacgaaacat
     1981 taaaacaatt atctaaacca caaatttaac tactacttct catcatgtga ctaagcgaaa
     2041 ctgctgactg gaggtcagca agctggaagc gtgtttagcg gagcgatgct tagaaacaca
     2101 tgatagaagt gtggaggagc tttgctcctc ctagtttatt tattatatag acaatctttt
     2161 ggcgaaagcc aacctaaaag gaactatttt ttatgacctc atataataaa aaaatagtcc
     2221 gcacttcttc ctatattgaa atttgggaat atgaaaagcc aatattttca aaaggaaaat
     2281 ctattttaga tactaatact gaaaacaagg aaaaagcaaa acgcagaaca tttgatgaac
     2341 taacacccct agaacaagaa caacgtcttg aacgtatgaa gaagactcgc ttagaagcca
     2401 agtggaactt actccgtcta gttgattgta attttgatga tacaacttct tttcttacac
     2461 tgaccactaa ggaaaatatc agcgatagaa accacttcaa agactcactc aaaacattta
     2521 ttaaacgctt taactaccac atttttaata ccaagaaaag taaattaaaa tatatagcag
     2581 tattagagag gcaaaaacgt aaagcatggc atagtcatat tttgctattc agtgttccct
     2641 atattccaca taagcaatta ttagaacttt gggggcatgg tgcagtatgg ataaataaag
     2701 ttgacgtcga cagcaaagaa aatcgcggtc gatatgtcac aaagtatttt gaaaaaggta
     2761 ttggacaaga attgttggaa aacttcggaa agcaagccta tttttcatca cgcaacttga
     2821 aaaagcctga tgaagataaa ttttacactt atgaagattt taactatgat agttcagtcg
     2881 tgctatatga aacggaatac actagtaagg tctataaata cggtcagtat ttcgataatc
     2941 atgtaaagta caagaaaata agactagatg aataaaggag taagtcacat gatagcaact
     3001 gttactaaga atgacctaat tgccctcggt ttctttgagg gaacatctaa acgtattatc
     3061 cgccaaggga aagagctact gataacccga ggctttacag tctatcagaa caagcgaatt
     3121 ggtactatac ctgctactat tgctaccgaa ttactcgttt ttgatgttca aaacagtacc
     3181 ctcaaggagt aaaatatggc aattagaaaa ggtaaagacg gtaattgggt agttgatatt
     3241 agcaacggtt ttgacccaat aacactaaag caacgtagac ttgtcagaaa gggctataag
     3301 acgaaaaaag aagctattga agcagaacac tacttacgaa gtgtagagtt aaaagaacgc
     3361 ttttatggag ctaaaataac tatccccata ctatatgaac tacttaagga ggaagatagt
     3421 ataaatcatc gaaaagcaag ctatatcaat acacaagata ataattacaa caaacacatc
     3481 aaagattatt tttctatggt cgataatgtc ggaaaactaa cctatgaaga catctaccaa
     3541 tttagagaac atcttaggca aaaagtagct aaaaattctg ataaaccgtt aagcacaaat
     3601 actattaaca aaatcatgat tttactcaaa aaaatttttg atgttggttt gcgaaaaggc
     3661 tattactcct ccaatccagc aaaattaata aaaaagttgc caattgaaaa aacaaaaatg
     3721 caattttgga cagtcaaaga atttcagaag tttttgacac tatttgaacc cgaagaatac
     3781 aatatcaaac tactctttac tgttctattc tttacaggat taagacttgg ggaagctctt
     3841 gccctaacat ggcaagacat cgacttttca agtaatacaa ttcatatcac gaagtctgtc
     3901 tatgttaata aaggagtaac tcatatcagc acaacaaaaa ctaaagcaga aacaagaaga
     3961 attgttatca ataaaaaatt aagccaagaa ttacaagatt ggaaaaagcg acaaaaacat
     4021 ctattagagc aatttaccaa caatagccta acattacaag tgtttcaaaa tagtcctatc
     4081 acaattacaa aaaatgctat tgaaaagcag tacaagaaaa tcattgaacg tgatagcaca
     4141 ctaaaaaaga tacgcataca cgattttagg cactcacacg cttccctgct gattaaccaa
     4201 ggggaagatt atctagttgt aaaagagcga ctaggacatg cttctataac aaccacgatt
     4261 gatacctact ctcacttgta cccaagtaag caaaaggatt tagctgataa actagatgat
     4321 ttactataaa gtaattgagt tttataaatg gaaagtttat aattaaatca tggatacatc
     4381 acaagtaata aaagcacatg aagtagctaa aaaagcacac tttggacaaa ttgatagagc
     4441 aggaattgac tacattaaac accctgaaac agtagctagt tttgtcgcaa ctgatgaaga
     4501 gaaagctgtc gcctatctac atgatgtaat tgaagatact tcactaaccc tactagacct
     4561 aaaaaaggaa ggtttttcaa aaaacattat agaagccgtc gatatactca caaagaaaaa
     4621 aggacaagat tatcaatctt atctcaatct agtaaagaaa aatgaactcg ctagagttgt
     4681 aaagttggcg gatttacggc ataattcaga tttaacaaga ctaccattaa ttactgaaaa
     4741 agacttagag agaaataaga aatacagttc tgctattaga tttttaagag caaagaaaaa
     4801 aagttagtaa ctaaactata aaattttata aagagaaaac aaaagacaag gcttataaac
     4861 tttgtcttta ttactatact ggcggtcggt ctcgaactgg cacatccttg cagatactac
     4921 aattttatta aaataaataa ctataaaaag tgaaattttt tattgagaaa cttttagact
     4981 aggagtataa tgtatctaaa ataactatta ggtggctgtt atatgaataa tgttgttact
     5041 acacaaattt ctattcaact tagtcaagag ttaaattctt tattaaatgc tattgttgaa
     5101 gaaaataata caacaaagac tgactttatt agacaagctg ttatagagaa aattgaagat
     5161 atgtatgata ttaaggtcgc tgatgaagct tataaaaaat gggttgaatg tggcaaaaaa
     5221 gctacctcac atgaagaaat gatgagacgc tatggctaaa ttatacgcaa tatctgatat
     5281 acatggatac ttggatgaat tcagagacgc tctcaataaa gtaaatttaa acgataaaga
     5341 taatcgccta tttttactag gagattatct tgataatgga cttcaatctt ttcaagtcat
     5401 ttccaaaata atcgaacttg aggaggttta tcctaatcaa attattactc ttctagggaa
     5461 tcatgaagaa tggttttatg attggttgat tttagataaa cctactgctt cagcatttcc
     5521 agaaacaata aaaagcttct tctctccaga ggaattgaac tatattttta aatcgaatgc
     5581 taacaacttt gaaacaggtg ttagaaatga aattaaaaat aatatcaaat tcaacccatt
     5641 tataaactgg tttaaaaagc gatataggga taaacgctat tatgaaactg atacccaaat
     5701 ttttgttcat gcaggcattg atgaagaagc aggaatgctt tggaaagaac taacgagttc
     5761 aaagatattt acaaacaaat ttccaattac cactggtaga tttcataaag ctattatttc
     5821 gggccatatt gcttcttggg aagtagctaa agatagaaga tacctaggta agatttacta
     5881 tgatagtaaa agtcattact taattgatgg agatgtaacg aatagcaaaa caatacctgt
     5941 tctttactat gatacaatta cccaaaaata tcactttcta taacttttaa tcatgtgctt
     6001 ttatatgaaa ttagtaatta ttagtaacaa ttccaagaaa tttcttatga cataacaaaa
     6061 agacaaggtc ctaaaacctt gtctttaata ctataccggc ggccggggtc gaaccggcac
     6121 gtccttgcgg acactggatt ttgagtccag cgcgtctgcc aattccgcca cgccggcaaa
     6181 tagtaactgg ggtagctgga ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta
     6241 ccgcttggct ataccccaat ataaaatagg cgagtgatgg ggatcgaacc cacgcatgcc
     6301 agagccacaa tctggtgtgt taaccacttc accacacccg ccataattct attaacacgg
     6361 gcagtaggaa ttgaacccac actgaaggtt ttggagacct tagttctacc tttaaactat
     6421 gcccgtaaaa tggaagggga gggattcgaa cccccgaacc cgaaggagcg gatttacagt
     6481 ccgccgcgtt tagcctcttc gctacccttc caaaatatat aaatggcgcg agacggaatc
     6541 gaaccgccga cacatggagc ttcaatccat tgctctacca actgagctac cgagccttat
     6601 tgcgggagca ggatttgaac ctacgacctt cgggttatga gcccgacgag ctacctagct
     6661 gctccatccc gcgttaatat aaaaggagga tgtgggattc gaacccacgc acgcttttac
     6721 acgcctgacg gttttcaaga ccgttccctt cagccggact tgggtaatcc tccaaaatag
     6781 ttttatacgg gaacaagccc gtgtcctctt agtgaacaga taatattcca atcccctagt
     6841 aatggactaa acactatggg cacgagtgga ctcgaaccac cgacctcacg cttatcaggc
     6901 gtgcgctcta accacctgag ctacgcgccc aagtcaaaaa cttggtacaa agaacaaagt
     6961 tcaaagcggg tgacgagaat cgaactcgcg acaacagctt ggaaggctgt agttttacca
     7021 ctaaactaca cccgctaaa
//
LOCUS       DAVIME010000075         7029 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVIME010000075 DAVIME010000000
VERSION     DAVIME010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.075"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(388..1332)
                     /locus_tag="VV588_002019"
     CDS             complement(388..1332)
                     /locus_tag="VV588_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HEU7084286.1"
                     /translation="MKKNDLFIDVSSHNGYDITGILADMGTQNTNIKISESTSYINPC
                     LNAQIEQSNPIGFYHFAWFGGDIEEAEREARYFLENVPQKVKYLCLDYEDHASGDKQA
                     NTDACIHFMEILKENGYEPIYYSYKPFTLNNIYYEQILAKFPTSLWIAGYGLNDGLAN
                     FEYFPSMDGIRWWQYSSNPYDKNIVLLDDEEATPKWKRNDTGWWYEYHDGSYPKEEWE
                     KIAGIWYYFDERGYSIASRWLKDDGKWYYLKENGAMATGWVQYKDKLYHFKEENGEMS
                     SKELVQVEGGWYYVNEDGSRSDKPALTVLPDGLIVTTK"
     gene            complement(1342..1620)
                     /locus_tag="VV588_002020"
     CDS             complement(1342..1620)
                     /locus_tag="VV588_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000611519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU7084287.1"
                     /translation="MINWKVRFNLKNKTFLLRVAFALALPILAYFNLKLEDLVSWGVI
                     LDLLGKFFVNPYLVGLTIVNILNIIPDPTTSGISDSKRALEYQEPSED"
     gene            complement(1624..1923)
                     /locus_tag="VV588_002021"
     CDS             complement(1624..1923)
                     /locus_tag="VV588_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084288.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKVDSNRREGRLMTHLEKTTTELTTITHTVGDIQKEMVCMNDRMEEIEKGE"
     gene            complement(1934..3958)
                     /locus_tag="VV588_002022"
     CDS             complement(1934..3958)
                     /locus_tag="VV588_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084289.1"
                     /translation="MGIDQYLKVIKEGVFGRDVRQAIHDGIEQVYEDATFDGNANMEV
                     AKARGEHNNLSERLKNMVAQIQSLSDSAPKGVYKNIEALNTAFPKGRDGIYLTQNDGK
                     WNFWDGSKWVPGGNYQSPAQPDLEYNDIDYSAISDIELWAQIHEMYANGYDIEKGTGY
                     PIFSKTNGEIGSIITGSGTQNYWTKRTIVVEQGEVYSARIQQAANSAYYVYFLDEGGS
                     VIARAVKNKGVATKPERYYFSVPKGSKKMLILSFESGSVVWKGLSKNKLTTFTKTALP
                     GKFENDTSKLGQFRTLDRRVSTKTIQYCKTETLIRVNKSGYLFFIDTFNENEEYLKTL
                     TENVEIIIPAGTYYRLTIQTVDDREQKADVSTMYYSITCYQKSDNDFNVLNSLAHARF
                     NSNFKFQSKLYGIRKSDISRRYPAETLIDLGIEGLQSFAIDIGNNIGYAFGWYNNTSK
                     AIKFDLSTKRELERINKPDSGHDNDAVFVNGNVYIASADKRSDDVASLLYKWNIEENT
                     VTKINVSGVIGKPENGSRRIISGICSAENNPENLYIVTTDHDYNLPFDGMHKEDDYLS
                     IYYYSPQNNTGYLLWRSKWDELYVQGATAVNDIMYIACNHQHTSTEGYKGIVIKVIDL
                     VARMQVDEIELIGDFEPESINHVYENGNLYLLLGIAKYNSFSKVVKIKID"
     gene            complement(4136..5311)
                     /locus_tag="VV588_002023"
     CDS             complement(4136..5311)
                     /locus_tag="VV588_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU7084290.1"
                     /translation="MYAVSLINGANVTPIHDSEAGGNKLLSAIVKLEINKVGQFNFQF
                     LPNNAGYKALIKPLQTMVQVVNMMTGKEIFYGRIVPVTNDMAESGVFTFAYNARSELD
                     FLNDSKQRQMLYQGKKSDFVRMILSFHNENLESYKEFYPGDLADLIATGDKMEAEVDP
                     SKSTLATLTDLILNEYGLEMKIRKEEGKKYLDFKRRIGKDSNTAIKLSVNLLTLKQHI
                     DPGGIVSRLLVYGKQNSKTNKRITISSVNNGKDYLDRADLISEYGIRMETVVFDEIED
                     PVKLKKAGEEQLASQKAVSYQYHVSAVNLSHINPNFDEFEEGDTYPVINPVMNIDERL
                     RVVARQIDLLNVERSSLTIGEKFKSAEEWQLDNIRKQTRQLVTANQLKEQQARLEEV"
     gene            complement(5374..5544)
                     /locus_tag="VV588_002024"
     CDS             complement(5374..5544)
                     /locus_tag="VV588_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000372136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084291.1"
                     /translation="MDQITDKIVVEVPKQDSQPVYLQVDGQTFAKLIVGHISNEQAQR
                     MIILDQGGAVGW"
     gene            complement(5544..6827)
                     /locus_tag="VV588_002025"
     CDS             complement(5544..6827)
                     /locus_tag="VV588_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084292.1"
                     /translation="MPEGSLKNLTEGLNLSFATIGSMFDVLFGSLNEKDNIDLLTKLG
                     MDSNTAQTIITTTTQIRDSISSALETAINLASDGAGKIADFFEWFKKGGVAVDALKSA
                     VVGVTSAWAGYKIATSIITGVEKVRNVVLGVSNGLMIARAVHTGALTTAEGAHAAATV
                     AGTGAMTTFNAVMAANPIMMIVLAIGALVAGLIWFFTQTETGQKIWSSFVEFLSNAWN
                     FVVNVGTKLWQDLADFFSLLWNSITTAAQYYWNSLINFFTNIWSKISTVGQFFFNMIY
                     NSISTVWSSISSFVSDTLNTIFNTVSSVFNNVWVTVTNIWNGIKNSISDAIEGAKNIV
                     SNTIEKIKGLFNFEFKWPHLKMPHFTFEGSMNPLEWAEKGVPSIGVEWYAKGGIMTGP
                     TVFGMNGNNLMVGGEAGPEAVLPLNKETMGMLQAL"
BASE COUNT         2078 a         1478 c         1102 g         2371 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagaaaatg gttttagata agattgcata agtcaaaagc cttttaaaat
      181 aagcctttat acgttataaa gtacatatac tttttaccat aaaaatacaa aagttttcac
      241 cttttgcccc tttgattatc tacttttgta actttggtac cgacatcaat gtcggttagt
      301 tagatatttt cttaattcag acaaacaaaa aaaccgcaag ctattgcctg cggtttgtgt
      361 aatctaattt gaaaattctt tctgttttta ttttgtggta acaattaaac cgtcgggcag
      421 aacagtaagc gctggtttat ctgaacgact gccatcctcg ttgacatagt accagccgcc
      481 ttcaacttgg acaagctctt ttgaagacat ttcgccattc tcttctttga aatggtatag
      541 cttgtccttg tattgaaccc aaccagtggc catagctcca ttttctttga gataatacca
      601 cttaccatca tccttcaacc agcgagaagc tattgaataa cctctctcgt cgaagtagta
      661 ccagattccg gcaatctttt cccattcttc tttgggataa gatccgtcat ggtattcata
      721 ccaccatcca gtatcatttc ttttccattt gggcgtagct tcttcatcat ctaataaaac
      781 aatgttcttg tcatacggat ttgaagagta ttgccaccag cggataccat ccattgatgg
      841 aaaatattca aagttagcta gcccatcgtt taaaccatac ccggcaatcc aaagactggt
      901 tgggaatttc gcaagaatct gctcataata aatattatta agcgtgaatg gcttgtagct
      961 gtaatagatt ggctcgtagc cattttcttt gaggatttcc atgaagtgaa tacaagcatc
     1021 cgtgtttgcc tgtttatctc cactagcgtg atcttcgtag tcaagacaca agtattttac
     1081 tttttgaggc acattttcaa ggaagtagcg tgcctctcgt tcggcttctt cgatgtcacc
     1141 gccaaaccaa gcaaaatgat agaatccgat agggtttgac tgttctatct gtgcgtttaa
     1201 gcacggattg atatagcttg tactttctga aattttgatg ttggtattct gtgtacccat
     1261 gtcagccaaa atacctgtaa tatcgtatcc attgtggcta gatacgtcga tgaacaagtc
     1321 gtttttcttc attgttttct cctaatcttc gcttggttct tgatactcaa gagcacgttt
     1381 gctatcagag attcctgatg ttgttgggtc tggaatgata tttagaatat ttacaatcgt
     1441 caaccccaca agataagggt tcacaaagaa tttgccaagc aagtctaaaa tgactcccca
     1501 gctaaccaaa tcttctagtt taagattaaa atatgcgaga attggcaaag ctaaagcaaa
     1561 tgccactcgc aataagaatg ttttattttt taagttaaat cgtactttcc agttgatcat
     1621 gtgttattct cctttttcga tttcttccat gcggtcgttc atacagacca tttctttttg
     1681 aatgtctccg accgtatgag tgattgtggt taattctgta gtggtttttt ccaggtgagt
     1741 catcaaacgc ccttctcgtc tgttagagtc gacctttgac tgctcgtgca aatccataat
     1801 cttcttctct cgcttgtccg aagtcttgat aagatatcga atgataataa agaaaagcaa
     1861 gataaacaaa atcgcccaag ctacctgact ttgagcgatt ttttcagctt cttcaatcgg
     1921 catataacct cctttaatct atttttattt ttacaacttt tgaaaaagag ttgtacttag
     1981 cgatacctaa aagcaaatat agattcccgt tttcgtatac atggttgatg ctttcaggct
     2041 caaagtcacc aataagttca atttcatcaa cctgcatacg tgcaactaaa tcaatgacct
     2101 taatcacaat tcctttgtag ccttcagttg acgtatgctg atgattacaa gcaatataca
     2161 tgatatcatt tactgctgtt gcaccttgaa catacaattc gtcccattta gatctccaca
     2221 aaagatatcc tgtattattt tggggcgaat agtagtatat cgatagataa tcatcctcct
     2281 tgtgcattcc gtcaaacgga agattgtaat catggtctgt agtcacaata tatagatttt
     2341 ctggattgtt ctctgctgaa caaattcctg agataattct tcttgagcca ttctccggct
     2401 taccaattac tcccgaaaca ttaatttttg ttacggtgtt ttcttcaata ttccatttat
     2461 acaataagct tgcaacatcg tctgaacgtt tatctgcaga agcaatataa acattcccgt
     2521 tcacaaaaac cgcatcatta tcatgacctg aatctggttt gttaattcgc tctagttctc
     2581 gtttcgttga taaatcaaat ttgattgctt tcgaagtatt gttataccaa ccaaacgcgt
     2641 aaccaatgtt attgccaatg tcaatagcaa atgactgtag accttcgatt ccaagatcaa
     2701 ttaaagtttc tgcggggtat cttctgctaa tatcagattt tcgaattcca taaagtttcg
     2761 attgaaattt aaaattcgaa ttgaaacgag catgcgcaag cgaattcaga acattgaaat
     2821 cattgtcaga tttctgataa catgtaatcg aataatacat agttgataca tcagccttct
     2881 gctccctatc gtcaacagtc tgaatcgtta atctgtagta ggttcccgcc ggaataataa
     2941 tctcaacatt ttctgttagt gttttcagat attcctcatt ttcgttaaaa gtgtctatga
     3001 agaacaaata gccactttta ttcacacgaa tcaatgtctc tgttttacaa tattgaattg
     3061 tttttgtcga aacgcgtcga tccaatgtcc tgaattgccc taattttgat gtatcgtttt
     3121 caaattttcc tggtaatgca gtttttgtga atgttgtaag tttattcttc gacaatcctt
     3181 tccaaacaac agaaccagat tcgaatgaga gaataagcat ttttttgctc ccttttggaa
     3241 cgctgaaata gtatcgttca ggttttgttg ctacaccctt gtttttaact gcacgagcaa
     3301 tgaccgagcc accttcatcc aaaaaataga cataataagc agaattggca gcttgttgga
     3361 ttctggctga gtaaacctct ccttgttcaa caacaatcgt ccttttcgtc cagtaattct
     3421 gtgtacctga accagtaatg atcgagccaa tttctccatt tgtttttgaa aaaatcggat
     3481 agccagttcc tttttcgata tcatagccat ttgcatacat ttcatggatt tgcgcccata
     3541 gttcaatatc actaatagct gaatagtcta tgtcattgta ttcgagatca ggctgagctg
     3601 gactttgata atttccgcca gggacccact tagagccatc ccaaaaattc cacttgccgt
     3661 cgttttgagt taggtatatt ccatctcttc cttttggaaa agcagtgttt aacgcttcga
     3721 tatttttgta aacacctttt ggagcactgt cagacaaaga ttgaatttga gctaccatat
     3781 tttttaatct ttctgaaaga ttattatgtt ctcctctcgc cttagccact tccatattcg
     3841 cgttgccatc aaatgttgca tcttcataga cttgttctat accgtcatga atagcttgtc
     3901 gaacatcgcg accaaaaact ccttccttga taacttttaa atattggtca attcccattt
     3961 aaactttcct ttctagattt tcaattcgtt tcaatagatc atctaagtca actttctttg
     4021 aaattagcaa ataatccagt tttttcttat cttgagcaga taagagttgg ctagactgtt
     4081 cgttcaccgt attattgaca gtttcaactg tctctgcagc tgtattagca ataactcaca
     4141 cttcttccaa tcttgcctgt tgctctttaa gctgattagc tgtaactaat tgccgagttt
     4201 gcttacgaat attatctaat tgccactctt ccgcagactt aaatttttct ccaatcgtca
     4261 aactagatct ctcaacattt aataaatcaa tctgacgcgc aactactctt aaacgttcat
     4321 ctatattcat tacagggttt attaccgggt aagtatcccc ttcctcgaat tcgtcaaaat
     4381 tcgggttaat atgagacaag ttaacagcag aaacatggta ttgataacta actgcttttt
     4441 gtgatgccag ttgttcttca ccagccttct tcaatttaac agggtcctct atttcatcga
     4501 atacaactgt ttccattctg ataccatact ctgaaatcaa gtctgctcta tcaagataat
     4561 cttttccatt atttacagag ctaatagtaa tccgcttatt ggttttactg ttttgctttc
     4621 cgtatactag caaacgggaa acaatgccac ctggatcaat atgttgcttg agtgttaata
     4681 aatttactga taacttgata gcggtattac tatctttacc aattcttctt ttaaaatcta
     4741 ggtatttctt cccttcttct ttccgaattt tcatttctaa gccatactca ttcaaaatca
     4801 agtccgtcaa agtcgctaga gttgatttgc ttggatcaac ttcagcttcc attttatcgc
     4861 cagttgcgat caaatctgcc aagtctcctg gataaaattc tttgtacgac tctaagtttt
     4921 cattatgaaa actcaaaatc attctgacaa aatcagattt tttcccttgg tataacattt
     4981 gtcgttgttt gctatcattt agaaaatcta gttcagatct agcattatat gcaaaagtaa
     5041 atacaccact ttctgccata tcgtttgtaa ccggcacaat tcgaccatag aatatttctt
     5101 taccagtcat catgttgaca acctggacca ttgtttgtaa gggtttaatt agagctttgt
     5161 aaccagcatt attcggcaga aattggaaat taaactggcc aactttgttg atttctaatt
     5221 tgacaatcgc agacaaaagt ttgttcccgc ctgcttcaga atcgtgtatc ggtgtaacgt
     5281 tagcaccgtt aatcaaacta actgcataca tctaaatcag ctccttaaac cacttaaacg
     5341 agatcctgcc attgaaattt acggcatatc ctcttaccat ccaactgcac ctccttgatc
     5401 aagaataatc attctttgag cttgctcatt actaatatgc ccaacgatta actttgcgaa
     5461 tgtttggcca tccacttgca aatataccgg ttgtgaatct tgttttggaa cttcaacaac
     5521 aattttatcg gttatctgat ccattataag gcttgcagca tacccattgt ttctttgtta
     5581 agaggcaaga ctgcttcagg tccagcttct ccacctacca tgagattgtt gccattcatc
     5641 ccaaacacag tcggtccagt catgatacca cctttagcat accattctac accaatgctt
     5701 ggcacgcctt tttcagccca ttccaaagga ttcatcgatc cttcaaaagt aaaatgtggc
     5761 atcttcaagt gtggccattt gaattcaaaa ttgaacaatc ctttaatttt ttcaattgta
     5821 tttgaaacaa tattttttgc accctctata gcatcagaaa tactattttt aataccattc
     5881 caaatattcg taactgtaac ccatacattg ttaaaaacac tagaaacagt attaaatatc
     5941 gtattcagag tatcactaac aaatgagctt atagatgacc atactgttga aattgagttg
     6001 taaatcatgt taaagaaaaa ctgaccaact gtgcttattt tcgaccaaat attggtgaaa
     6061 aaatttatta aagagttcca ataatactga gcagcagttg ttatcgaatt ccacaaaagt
     6121 gaaaagaaat cagctagatc ctgccaaagt tttgtcccaa cattgactac aaaattccaa
     6181 gcatttgata gaaactcaac aaaactagac catatttttt gtcctgtttc agtctgcgta
     6241 aaaaaccaaa ttaaacctgc tactaaggca cctatagcta acacaatcat cataatcgga
     6301 ttggcggcca ttactgcatt aaatgttgtc atagctccag tccctgctac tgttgcagct
     6361 gcgtgtgcac cttctgcagt agtcaaagcc ccagtatgaa cagccctagc aatcattaat
     6421 ccattactaa cacccaacac aacatttcgt actttttcaa cacccgtaat gatactagtt
     6481 gctattttgt atccagccca agcacttgta actccaacaa ccgcagattt taaagcatca
     6541 acagcgactc cgcctttttt gaaccactcg aaaaagtcgg caatttttcc tgccccatct
     6601 gatgcgagat ttatagctgt ttcaagtgct gaactaatac tatctctaat ttgggttgta
     6661 gtagttataa tcgtttgggc agtattcgaa tccataccca gttttgtcaa caagtcaata
     6721 ttatcttttt cattcaatga accaaatagt acatcgaaca ttgaaccgat agtagcaaaa
     6781 cttaaattta aaccttcagt aagattttta agacttcctt caggcaactt aaaaaccttt
     6841 tctaaaaacg taacaaaagc ttgagatagt tgaggaagta tatcattgaa taaaattaaa
     6901 aaaagtctcg gcaaagcaga tcctaactcg ctaagaagtt ctgttgcccc agttataagt
     6961 ccaggtaata aagcactaag aagatcaggt aaatagttcc ctaaaatctg aataatgcga
     7021 gataatccc
//
LOCUS       DAVIME010000076         5938 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVIME010000076 DAVIME010000000
VERSION     DAVIME010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.076"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            62..1204
                     /locus_tag="VV588_002026"
     CDS             62..1204
                     /locus_tag="VV588_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU7084293.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKWKRVSVTLDSGSSRAKKEAQ
                     KLLDERLEETLKKIQTTDIVYEHILDEWWTFYQKEIKGSSISSLTSSVNDFKKDFDLS
                     VKVSNIDTKYIQRFLNDLDLSRSKLERYKLILNLSLDYAVNLEYIEDNPARRAKLPKL
                     VKTIEDLEKTEKKFLEEDELERLLSELYRTDKTYRLGLLAEFMAYNGCRIGEAIALRK
                     ENIDFESKTVKINGTLDKTVGYSKGLKTTTKTAASFRTVSLSKRELEILKEFISINEL
                     SKNTRETFKDLGFIFVTKNGIPIQNNSFNLAIQKVNNRLKNPINKHLTSHIFRHTLVS
                     RLSENNVPLKAIMARVGHSDSRTTNKIYTHVTKKMDDNILNLLDNL"
     gene            complement(1291..1566)
                     /locus_tag="VV588_002027"
     CDS             complement(1291..1566)
                     /locus_tag="VV588_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU7084294.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(1673..2512)
                     /locus_tag="VV588_002028"
     CDS             complement(1673..2512)
                     /locus_tag="VV588_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU7084295.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQVYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            2654..3502
                     /locus_tag="VV588_002029"
     CDS             2654..3502
                     /locus_tag="VV588_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU7084296.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAVGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFIFGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(3595..4512)
                     /locus_tag="VV588_002030"
     CDS             complement(3595..4512)
                     /locus_tag="VV588_002030"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU7084297.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            4947..5152
                     /locus_tag="VV588_002031"
                     /pseudo
     CDS             4947..5152
                     /locus_tag="VV588_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            5486..>5938
                     /locus_tag="VV588_002032"
     CDS             5486..>5938
                     /locus_tag="VV588_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU7084298.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSRMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIDHQLSISTSTVIRKINDFHFKHDFSCLP"
BASE COUNT         1959 a         1145 c          985 g         1849 t
ORIGIN      
        1 aaaaggcatt aaatggccct ttttactata cccattttag caaaaaagtg aggtaaaatc
       61 aatgtggatg gaagaacttc ccaatggaaa atacaaattc tttgaaagat ataaagaccc
      121 ttataccgag aaatggaaaa gggtatctgt aacccttgat tctggatcaa gtagggccaa
      181 gaaagaagcg caaaagcttc tggatgagcg attggaagaa acgctaaaga aaatacaaac
      241 tactgatatc gtctatgaac acattttaga tgagtggtgg acattttatc aaaaagaaat
      301 caaaggaagc tctatcagct ctctgaccag cagtgtgaat gattttaaaa aggattttga
      361 tctatctgtg aaagtgagta acattgatac aaaatacatc cagcgttttt taaatgacct
      421 tgacctttca cgatcaaaat tagagcgata taaattaatt ctaaatttgt ctctcgatta
      481 cgcagtcaat cttgagtata ttgaagacaa tcctgcaaga cgtgcgaaac ttccaaagct
      541 cgtaaagact attgaagatt tagaaaagac agaaaagaaa ttccttgaag aagatgagtt
      601 agaaagattg ctttctgagc tatatagaac agataaaacg tataggttag gattgcttgc
      661 tgaatttatg gcttacaacg gttgtcggat aggtgaagct atagcactca gaaaagagaa
      721 cattgatttt gaaagcaaga ctgtcaaaat aaacggaacg ctagataaga ctgtaggata
      781 ttctaaagga ttaaaaacaa caacaaaaac agctgcaagt ttcagaacgg tttccttgtc
      841 aaagagagaa cttgaaatat taaaagaatt catctcaata aatgaacttt cgaaaaatac
      901 aagagaaacc tttaaagatc tcggattcat ctttgttact aagaacggaa tacctattca
      961 gaacaactcg tttaatttag cgattcaaaa agtaaataat cgacttaaaa acccaatcaa
     1021 taagcatctc acatcgcata tatttcgaca tacgctagtg agtaggctat cagagaataa
     1081 tgtgcctcta aaagcaatta tggctagagt aggtcattct gactctcgta ccacaaataa
     1141 aatctataca cacgttacaa agaagatgga tgacaatata ctcaacttgc tagataattt
     1201 atagttttgc cccttttttg ccccctatac ataaaaaaag cctgtcacac aagctcaaat
     1261 gcttgatatg acgggctttt tctaaattca ttatttaaca gcgtctttaa gagctttacc
     1321 agctttgaat gctggtactt tagaagctgc aattgtcatt tctttaccag tttgtgggtt
     1381 gcgaccttta cgttctgcac gctcacgaac ttcaaagtta ccaaaaccga tcaattgaac
     1441 tttttcacca gctgcaagat agtcagctac tgctgcaaat acagcttcaa ctgctgctgc
     1501 tgagtctttc ttagtcaatt ctgtagcttc tgctacttta gcgatcaaat cttgtttgtt
     1561 tgccatgtta atgattcctc caaataattt ctaattaaca aatataatca tatcctaaaa
     1621 tcccttttag gtcaagttaa aaacgctatt tcttcccatt ttatttattt ttttaggagt
     1681 ggtaacgtat caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg
     1741 tttccaaaac agaaattggc ttttcaacat aaacttgtaa gctttctttc atctcttttg
     1801 cccaatcatc actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg
     1861 atgttatcaa ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg
     1921 gctgcaattc atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca
     1981 agccagttac acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa
     2041 tataaagctc tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt
     2101 taccttcttg agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga
     2161 aggaactatc aacaacagtc acatctgcag tagataggct agcaccttgg cgtgctgctt
     2221 ctaccgtacc cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc
     2281 ataggtcttc aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat
     2341 tcttactttc ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat
     2401 aaacaacatt atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta
     2461 gttcaggttc aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa
     2521 tctttctatt ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt
     2581 aaaaatccta atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga
     2641 aaagaggtgt cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc
     2701 tatttatgct tttggactga cttattttgt agttccccat catctctttg aaggaggggc
     2761 gacaggcatt accctcatca ccttttatct ttttaaaatc cctgtttccc tcatgaacct
     2821 gctgattaat attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta
     2881 ttctagttta ctaggaacct tagctttgtc cgcctggtta gctttttttg agcatattcc
     2941 ccttcatatt gatcttcaag gtgatttact aatcacagcc cttatagcgg gaatcctatt
     3001 gggaattggc cttggaatta tttttaatgc tgtaggtaca actggcggaa ctgatattct
     3061 agctcgtatt ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga
     3121 tttttgtatt ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac
     3181 gcttttgttt gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc
     3241 cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga
     3301 tgacctcgga agaggtgtta cttttatttt tggtcaaggc tactatagta aagaaaattt
     3361 gaaaatcatc tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca
     3421 tcgaatcgat cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg
     3481 cttcaccttt gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat
     3541 catctatctt ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga
     3601 ccaattccga gttacttctt catcagcctt taactgatcc actaattggt caactgagtc
     3661 aaatttggtc atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat
     3721 atcttgatta aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac
     3781 atttttcccg acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac
     3841 ataaacgcca tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata
     3901 accaattgta cgaccacgag cattaccatg aactaccata cctcttgatg gaagcggtgc
     3961 ccccaaaagt tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt
     4021 tgaactaatc tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa
     4081 gtaatccttt aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc
     4141 aacaataatt ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag
     4201 actagcgaat tgactactaa aatcaaggag atataattct tctacacctt cgcgctttag
     4261 ttttctttca cgttcagcag ggttcaaaat atgcaaaaac aaatctggat gataaggctc
     4321 taaagcgatc tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct
     4381 cgcagccttg ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata
     4441 gccgagaaca acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat
     4501 agtaataatc ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga
     4561 aatgttgttt ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg
     4621 cttaactatg aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg
     4681 caaggagtga ttagacttgt tcggtaacca taaagtgtca tactatgctt atgtatgaaa
     4741 aagcaatgca actaactcct gagaacttta aattactaat tggtgccgaa aaggtagaat
     4801 ttagaatcga ggtacaccta tggctgtaaa atttacaaaa tgagacaact tgggcaagat
     4861 gtttgaagaa tttcctaaac tccctgattt gaagcaagtc actttccctg atgacaaaaa
     4921 aagccaaagc agtaaagaaa aactagatga ctgctttcca acaacttcca tctagtgtgc
     4981 ttcagactgg gctatttttc tctccatctg ttagcttgga ttctcagacc gtttcagcta
     5041 aagaatatct tttcccttat cagaaggaac ggctcaagcc attcagacaa gtgaagggac
     5101 gacaagccaa tatttgaaac cagatagcag ttcttatagt caattgaaat aaaatctgaa
     5161 gaaatcgagt aggaaactca aatcaatttt taacagtgtt ctattccaga ttcatactca
     5221 atgaaaatta aagtgcaaac taggaagtta gccgcaggct gtacttgagt acggcaaggt
     5281 gaaactgacg tggtttgaat ttgattttcg aagagtatca atccactata catattaaaa
     5341 agtatgggta tcaaaataaa aaggctctat aatatttgta gtgggtaaat ccactataga
     5401 tattatggag cctattttgt gtagaaaaaa agtcccatat gacctataat gaaaagcgat
     5461 caaacaactc attagaaaga ttcatatgga acaattacat tttatcacaa aattactaga
     5521 cattaaagac cctaatatcc agattttaga catcatcaat aaggatacac acaaggaaat
     5581 catcgccaaa ctggactacg acgccccatc ttgccctgag tgcggaaatc aattgaagaa
     5641 atatgacttt caaaaacctt ctaaaattcc ttatcttgaa acgactggta tgcctactag
     5701 aattctcctt agaaagcgtc gtttcaagtg ctatcactgt tcaagaatga tggtcgctga
     5761 aacttctatc gtcaagaaga atcaccaaat tcctcgtatt atcaaccaaa aaattgcgca
     5821 aaagttgatt gagaagattt ctatgaccga cattgatcat cagttgtcta tttcaacttc
     5881 aactgtcatt cgcaagatca atgattttca ctttaaacat gatttttctt gtcttcct
//
LOCUS       DAVIME010000077         5273 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVIME010000077 DAVIME010000000
VERSION     DAVIME010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5273
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.077"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..1138)
                     /locus_tag="VV588_002033"
     CDS             complement(<1..1138)
                     /locus_tag="VV588_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU7084299.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIKISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYAINGSINTPKDSSAPFELINEL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKLNDDDANRFKT
                     MSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVESFKIDYQETIY
                     YHCLYKNTLKYQLLKVFSSIPGLEKYPLTRFKNSIVIYDTKLELKKTHNLINSKFSSK
                     DIVNQLEVTEKDFDFYYKKARHKNPDYSIQENQVNLTELNLVRLL"
     gene            1500..1856
                     /locus_tag="VV588_002034"
     CDS             1500..1856
                     /locus_tag="VV588_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084300.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            1861..2226
                     /locus_tag="VV588_002035"
     CDS             1861..2226
                     /locus_tag="VV588_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU7084301.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLIPGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            2213..4036
                     /locus_tag="VV588_002036"
     CDS             2213..4036
                     /locus_tag="VV588_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU7084302.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            4150..5016
                     /locus_tag="VV588_002037"
     CDS             4150..5016
                     /locus_tag="VV588_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7084303.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
BASE COUNT         1847 a          772 c         1004 g         1650 t
ORIGIN      
        1 tcaataacct aactaagttt aattcagtta gatttacttg attttcttgg atgctataat
       61 caggattttt atgtctagct tttttatagt aaaaatcgaa atctttttct gtaacttcaa
      121 gttgattcac tatgtctttt gatgagaatt tactatttat caagttgtga gtctttttca
      181 attctaattt tgtgtcataa attactatac tatttttaaa tctagttaaa ggatattttt
      241 cgagaccagg tattgaagaa aatactttca gcaattggta ctttaaagta tttttgtata
      301 agcagtgata ataaatagtc tcctgataat ctattttaaa actttctact tcaggggaag
      361 ggactagaca attaccttga tctaaataca tagccataca ctcgtcaatt gtaagatgac
      421 gatatcgaag ttgtactaat tgccaatcaa tattagtctg gtattgattt aaactataag
      481 acatagtttt gaaacgattt gcatcatcgt cgttaagttt aatataaaaa tcgggattag
      541 gattataaat aaaaaatctt ccgtcttcat tttcaatgaa gaaccaattt ttatagtctt
      601 ttaaaacatg aaaatactgc tctttgatat ttaagtcggt atgattaaac ttttgaaaca
      661 actcatttat taactcaaaa ggagcagagg agtctttagg ggtatttata gagccattta
      721 tagcatatat taatcctttt ggtaatgcag tatctttctt aggcttataa tcttttgtta
      781 aaaatacagg aactttatct gtatcatgaa taattaagat gtcaatttct ttgttgtcta
      841 tagtttcagt ttgtatgcta attttaattt gattatttgt tgatataaag agtttatgta
      901 gtaaatctgt tagatcttct tcatttcttc tattatcatc attgtttaca ccgattatat
      961 ctaaagtgat attatcaatt ccaaagatga tataacaatc ttcgtgatgt gatgtattga
     1021 caaaatttaa gatatcacgc accaattcag tttttgaatg atgccatttt tgtttaaaat
     1081 catgaaactc atcttcgggt gtattcaata gtaagtgtat ttgatctaga ctcagcattt
     1141 ttatttctcc aaatattagt ttacagaaat tttatcatag aatcagagaa agtcaatcat
     1201 aactatatta gctgtgatac ctttttcaaa tcttccctgt tatcctaata tcattcatag
     1261 aaaatcaatt tttgattttc tatgggggtt tgggggcgaa gtcaccaagt tatcttatcg
     1321 ttggctgtca aaactagaaa gttttgatag gctggcgata tgatttttga gatattgtgg
     1381 acacaatatc tgagctcgca aagccttaca agaatgaaaa tcagttgttg gaaaagtgta
     1441 ctgacattgt atggtagctc acattgtcag tacaagtatt ttggaaagga agtagcagta
     1501 tgaaacgaga tgtgcgtgat attcggaaac aatttcgttt aacagaagca gaagaaaagc
     1561 aaattctagc tttgatgaga gagcggggag agactaattt ctctgatttt cttcgtaaaa
     1621 gtttactttc ctctgattta caaaaacaga tggagacatg gtttgccctc tggcaatccc
     1681 aaaaactaga acaaatcagt cgtgacgttc atgaagtttt aatcttggca cagtcagaac
     1741 gtcaagtcac ccaagagcat gtatctattc tcttaacgtg cgtgcaggaa ttgattcaag
     1801 aggttgcaaa caccataccc ctcagtaaag aatttcgtga gaagtacatg aggtaagcac
     1861 atggaacatc gttaccgaac caatctcaag aaagtgtttt tgtctgatag tgagttgaac
     1921 caactaaata taaatatcga tcaaagtggt tgtaaatcct tttctgaata tgcgagacga
     1981 actctactcg atcctggtat gaattttatc acgattgaca caaacggtta ccaagattta
     2041 gtgtttgagt taaagaggat tggcaataat atcaaccaga ttgctcgaag tgttaatcaa
     2101 tctcagttaa ttcctggtga agaattgcag gagttgaaaa aaggaattgg tgaattgata
     2161 aaagaagttg ataaggaatt taatctgcaa gcgcagaagc taaaggagtt ccatggtcat
     2221 cactaaacac tttgccattc acggaaagag ttaccgcaga aagcttatca agtacattct
     2281 caatcctgag aaaaccaata atcttgcctt ggtgtcggac tatggcatga agaattttct
     2341 ggactttcct agctatgagg aaatggtgca gatgtatcat gaaaatttca tcagcaacga
     2401 tacgctttac gattttcgcc acgacaggat ggaagaaaat caacgaaaaa tacacgctca
     2461 ccacatcatt cagtctttct cgccagagga tcatctcact cctgaacaaa tcaatcggat
     2521 aggttatgag actgtgaagg aattaactgg tggcaaattt cgttttatcg ttgcgaccca
     2581 tgttgataaa gaccacctgc acaatcacat cattatcaat tcagtagata gcaattctga
     2641 caaaaagctc aagtgggact acaaggtgga gcgaaatctt cgcatgattt ctgaccgttt
     2701 ttctaaaatc gcaggtgcta aaatcattga gaaccgctat tctcaccagc ggtatgaagt
     2761 ctatcgtaag actaatcaca agtatgaact caagcagcga ctctattttt tgatggaaca
     2821 ttctagggac tttgaggatt tcaaaaagaa tgctccgcta ctacatgtgg agatggattt
     2881 ccgtcacaag catgccacct tttttattac ggactcaact atgaaacagg tggtgcgtgg
     2941 caagcaactc aatcgcaagc agccttacac agaagaattt tttaagaact actttgccaa
     3001 aagagaaata gaaagtctca tggaattttt attgctgaaa gttgagaata tggatgattt
     3061 acttcagaaa gcaaaacttt ttggactaac tatcaatcct aaacaaaagc atgtttcttt
     3121 tcaatttgca ggagtggagg taaaggagac agagctagac cagaaaaatc tttatgatgt
     3181 agagtttttc caagattatt ttaaaaatag aaaagattgg caagctccag aaactgagga
     3241 tttcgttcaa ctttatcaag aagaaaagtt atccaaagaa aaagaacttc caagcgatga
     3301 gaagttctgg gagtcctatc aagagttcaa gagtaacaga gatgccgttc atgaatttga
     3361 ggtggagttg tcactcaatc aaattgaaaa agtagtggat gatggaattt acgtcaaggt
     3421 caagtttggt attcgtcagg agggacttat ctttgtgccg aacatgcagc ttgatatgga
     3481 agaggataag gtgaaggttt tcatcaggga aaccagctcc tactatgtct accacaaaga
     3541 cgctgccgag aaaaattgtt atatgaaagg tcgaacctta attagacagt tcagctatga
     3601 aaatcaaacc attccattac gcagaaaagc gacagtcgat atgattaaag agaagattgc
     3661 ggaagtggat gctttgattg aactggaagt agaaaatcaa tcttatgtca cgattaaaga
     3721 tgagttagtg catgaactag cagcgtctga attaagaatc aatgagttgc aagaacgaat
     3781 gtcaaccttg aatcaagtag cagaatatct actggcttca gttgaaagta agcaagaaat
     3841 gaaattaaat ctttcaaaac tgaatataac tgagaatatc agtgctaata ttgttgagaa
     3901 aaaattgaag agcctgggga atcaactgga attggaaagg ggcaggtatg aaaagatggt
     3961 agtcaggcta gataaattta taaatcgctt aaatacagga ctttcaaaag gagatgggat
     4021 agattttcaa aaataggaat ctagccaata attatataca atgtgtatct tttgtaaaat
     4081 atatttgaaa tttagattta atcatgttac aattaacatt gaaatcaaat agaaaaggaa
     4141 gatgcaaacg tgggtacact attagcaaca agattaaaaa atagacgaaa agaattaaaa
     4201 atgtctcagc gagaattagc tgagggtatc tgtaaacagg ggcaaattag tcgattagag
     4261 agtggagagt tcacccctgg agcggatttt ttacatgccc ttgctaagaa attaaaagtt
     4321 agtatggact acttttttga tgagcaggtt gtagaggaag tcaatgagtt atcagagttt
     4381 aagaagttag cacagacatt tatcacaaat cgtaattatg aatctttaaa atatatatat
     4441 gaattggaaa atgtaaaagc ccatcgctta tctctagcag ataaatttta catggaatgg
     4501 ataaagtctc ttatagattt ttatttttat ggacagaaag aagaggcaat tacacgatta
     4561 gagaatatgc tacctcagtt aaatgtatct gatttgaact accttcaagt ttcaaacact
     4621 ctattcaatt tttattatga tattgaagat ttagaacgtt ttaatgagat tagagacaag
     4681 ctagagcatc aagtgaatca gcttaattta aacacaattg aagagttaga actatcaatt
     4741 aagttcaatt ataacgtttg tcgataccta tggttacaga aaaatattga agaagctatt
     4801 acgaaaatca cagctacgat aaagcaatgt aaggagtaca ggacaactta tctattagct
     4861 gatttgtatt tattgatggg aagtgtaagt gaaaattttt cttctaaaag ttcagtaaaa
     4921 gaatattttg agactgctca ttttctctac aaacttgagg aaaacatgtc aatggctttg
     4981 aaagtcgaac attattttgc agatataaca gaataaggaa tacggtgttc tagtgagcat
     5041 cgttttttaa atctaatttg aatacaaaaa agtattaaat aaaaaaaaat aaaaaaagat
     5101 tataaaaata cttgacaagc taattttgaa gtgataaaat aaatgcaaga aaacgaaagg
     5161 agaggtatat gagaagtttg tttaggaaaa ttgttgcttt gttagtcata ggattaatcc
     5221 tattagggac tgctggagga actcaagttc ataagatggc tagagggatt gat
//
LOCUS       DAVIME010000078         5211 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVIME010000078 DAVIME010000000
VERSION     DAVIME010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.078"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(359..1087)
                     /locus_tag="VV588_002038"
     CDS             complement(359..1087)
                     /locus_tag="VV588_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU7084304.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1245..2654
                     /locus_tag="VV588_002039"
     CDS             1245..2654
                     /locus_tag="VV588_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU7084305.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2672..3967
                     /locus_tag="VV588_002040"
     CDS             2672..3967
                     /locus_tag="VV588_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU7084306.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3972..4280
                     /locus_tag="VV588_002041"
     CDS             3972..4280
                     /locus_tag="VV588_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7084307.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4277..4585
                     /locus_tag="VV588_002042"
     CDS             4277..4585
                     /locus_tag="VV588_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU7084308.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1755 a          879 c          947 g         1630 t
ORIGIN      
        1 gggagattga aattcatttc tagcaatttt ttagaagtca cagtctacta ttctaacctc
       61 agtatactat atgtgttaca agaaaagact caaaaacttc tcgtcagtgt aagaatgttt
      121 gaaacactat ttaaaactaa ataactataa gaagtagatc aggtgaacaa tttcagtacc
      181 tactctataa gctatacgaa gatatttttc aacatgatgg ataaaacgat cactctttta
      241 aagctatctt atttagaaaa gagaaaccat ttaagcatag atgggacctt cttgccctgt
      301 tttaaatttt tcttaaacta gagtctgtaa aagattggct tcattttcac attttctcct
      361 aggaggaatg tcgtaatgca aaagaattaa attcaaataa atcatagcga tgacgactaa
      421 tcgagtactc aaacggagtt ccgttatcca aataagccac ttgttctact tcaaataccg
      481 gttccgttgg aaggagctgc aagtaatgtt gctcattttc tgaactagaa gaagctcgca
      541 agatttttgt agcactggca atatgcaatc ctaactttcc ttcaatgtaa ttgtaaatcg
      601 atttttgtaa aatatcttca gtaatacctg gaataacatc ggtactcata taagtttgtt
      661 ccagaacata aggtttaccg tcaataatac gcagacggta aatattataa actggactct
      721 gcaaagcgac ctgtagtttt tctgctaaaa attcatttgc aaattctaat ttgaagtgaa
      781 taatcctcga gtcaattgta gaatgagcat cttcagatat ttttgtcagt ccccggatat
      841 ctctttctgg aacgattaat tttctttttg agctgccacg agagagaaca aaggttccct
      901 gcccacgttt tctaaaaatt aagccctcag aaactaacaa gtctaaagct tttttgatcg
      961 tcattcgact acaggcaaac tgtttagcta atgtcatttc atcaggcaat tgttcgttca
     1021 tggtatattt attacaaaga atcttttcac gaatctcatt gtaaataaat aaatattttg
     1081 tactcattta atctggttct ctctataata ttctaatagt agtataacaa agttcaagaa
     1141 atgaggcaaa cacaagacat gtatcaacaa tttttaaaaa tgtctagaca aattttaaaa
     1201 ttatgctata ctttatgtat agaataatag aaaggaggtt gagcatgaaa aaaaagttag
     1261 tatttcctaa tctgttttgg tggggagctg cttctagcgg acctcagaca gaaggtcaat
     1321 atggaaaagt acatgaaaat gtgatggact actggttcaa aacgcatcca gaagattttt
     1381 tcgataatgt cggacctctt gtagccagta acttttttca tacttacacc gaagatttcc
     1441 acttgatgaa ggaaattgga gttaattctt tccgcacttc catccaatgg agtcgactca
     1501 tcaagaattt agagacaggt gagcctgatc caaaaggtat tgctttctac aatgccatca
     1561 ttgaagaagc taaaaagaac cagatggatc ttgtgatgaa tttacatcat tttgatttac
     1621 cagtggaact tcttcaaaaa tacggtggtt gggaaagcaa acatgtagtg gagttattcg
     1681 tgaagtttgc caagactgct ttcacatgct ttggagataa ggttcattac tggacaactt
     1741 tcaatgagcc aatggtcatt ccagaagcag gatacttata tgctttccat tatccaaatc
     1801 taaaaggaaa gggaaaagag gccgtacaag tcatctataa tctaaacctt gctagtgcaa
     1861 aagtgattca actatatcgc tcattaggac ttgatggaaa gattgggatt attttaaact
     1921 tgacacctgc ttatccaaga agtaattctc cagaagactt agaagcaagt cgatttacag
     1981 aagacttctt taacaaagtc ttcttgaatc cagctgttaa aggaactttc ccagaaagat
     2041 tggtaaaaca gctagagaga gatggcgtgt tatggagtca taccgaaaaa gagcttcaac
     2101 tgatgaaatc aaatacggtt gattttcttg gagtaaacta ctaccatcca aaacgtgttc
     2161 aagcacaagc aaatcctgag gaatatcaga cgccctggat gccagaccaa tacttcaaag
     2221 agtatgaatg gccggagcgt cgcatgaatc catatcgtgg ttgggaaatt tttccgaaag
     2281 ccatttatga tattgctatg attgtgaagg aagaatatga taatattcca tggtttatca
     2341 gtgaaaacgg aatgggtgtt gaaaacgaag cacggtttat cgatgaaaat ggagttatcg
     2401 atgacgtgta tcgtattgaa ttttatgaag aacatttaag atggctacat aaagccattg
     2461 aagagggaag tcactgtttt ggataccacg cttggaccgc atttgattgc tggtcttgga
     2521 ataatgcata taagaatcgt tacggattta tctccgttga tttagaaacg caaaagagaa
     2581 ccatcaagag ctcaggaaga tggtatcgca aagtaagtga caataacggt tttgaagtag
     2641 aaattgagga gtaaagagag gagatattca gatgaaaaac tcaaaattta tagatcaatt
     2701 tgccaccttt gctggtaaac tagggaacca aattcattta aaaaccctaa gagatgcatt
     2761 cgtaacagta atgccattat atattttggc aggtttaatc gttcttttga acaacacggt
     2821 atttaagtgg attttccaag gggatacatt aacaaaattc caatattggg gaataacaat
     2881 tgcaaacggt actttaagta tttcaggtat gattattgct gtaatggttg gttatttctt
     2941 agctaaaaac agagatttcg aaaacccgtt agcagcatca atgctatcat tagtttcttt
     3001 aattgtgatg atgccaaata cagtttctgt agttcctgac ggagcaaaag atgctgtaaa
     3061 catttcaggt gttctttcat tcaacaacac aggtacaggc gcaatgttcg ccggggttat
     3121 cgtagcgatt attgcaacag aattattcat tgaattatca aacgttaaag ctttacaaat
     3181 gaaccttggt gaaaatattc caccagctgt tagtagatca tttagcgtat tacttccagt
     3241 catgaccgtc atctccttat ttggggttgt ttcagcatta ttattcaata taactggaat
     3301 gaacttaatc tcaatcatta caatctttat tcaagaacca attcgtcata ttggtacaag
     3361 cttaatcggg gtcattatta tttactcttt aggaaatatg ttatggctat ttggtattca
     3421 ccaagcagtt atttacagtg ccatcctaga accattacta ttaattaaca ttactgaaaa
     3481 catcactgca gcaaataatg gacaagccat tccacacatc atcaacctat cacaaataca
     3541 aacattcgct ttaatgggtg gtagtggatc tacattatgt ttattaatag caacattctt
     3601 agtgagtcgc aatgctgtct ctaaaaacgt ggctaaatta tcttttggac ctggtatctt
     3661 caatatcaat gaaccagtat tattcggtta cccaatcgtt tataacattt cattagctat
     3721 tccatttatc acagttccag tccttggtat tttaatcagc tacttagcaa cagttacagg
     3781 attcatgagt cctgcattta tacaagttcc ttggactaca ccagtattct taaatgcatg
     3841 gttagcaaca gcaggggacg tgagagcagt tctagttcaa ttcatcatct ttgcacttgg
     3901 agttcttcta tacattccat ttatcaaagt taatgacaaa gttgttgaac aagaaatgga
     3961 aggttaagat tatgaaacaa attttattag tatgtaatgc gggaatgtcg acaagtatgc
     4021 ttgttaaaaa aatgcaacaa agtgcgactg aacgtgggat tgaaatctct atccaagcaa
     4081 aatcaatgac agaagctaaa aagaatatcc atgaagcaga tgtcattcta attgggccac
     4141 aaattcgtta tgagttactt gctgtgaaag aaattgcagg aaatatccct gtagatacca
     4201 ttgatatgcg ggattacgga atgatgaatg gagcaaaagt tctggaacaa gcacttgcat
     4261 ggataggaga aataagatga cagaagaaat ggaatatatc tgttttcagc tcattgccaa
     4321 tagtggagca gccaaatcat cctttattga agccatccaa ctagctaagg caggaaattt
     4381 aaaagaagcg aaaattaaag ttgaagaagc ggaagactcc ttagtagaag cgcacaagat
     4441 tcactctaat ctcatacaaa aagaagctac tggagaaaaa ataggattct ccttgctatt
     4501 tatgcatgca gaagaccaaa tggcttcaac agagattatt cagttgctat ctaaagaatt
     4561 catcgatctc tatcaaaata aataggaaca ctgtcattcc catctgtctt tattaatgac
     4621 gactacattg taggaacctc caaaagttgg acaaaatgat tgaaaggatt ggatcctgca
     4681 ttacacaaga tccaatcctt ttcttttact ctagttttta taatatgttg aatctagaat
     4741 agtccactgt agtttctaaa aaattgctgg aaatggatgt taagctccaa tttatttgtt
     4801 tatatcttat ttcagtttac tatactagct tattattcta gtgaaaaatt gaatgagcca
     4861 ctatttattt aatatgtatg atgagggaat gactcaaaaa cttcttgtcg atataagaat
     4921 atctgagata gtattttaaa acgaaaggac tataaaagct catttccttc gcacttattt
     4981 tatagagatc tatcattata ctctttagaa atcaaaaagc aacacacctt gtcatcgttt
     5041 tatcgtaaat ctgttaatga gggggctagt cttatctgca atctcaaatc agtgttttga
     5101 gctgaatggc actcgttttc tagtttgctc tttgatttta attgggcctt agtaaatact
     5161 actcttaaat taaactatag tgaattgaaa taagatgtga acaactctat c
//
LOCUS       DAVIME010000079         4949 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVIME010000079 DAVIME010000000
VERSION     DAVIME010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.079"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            77..439
                     /locus_tag="VV588_002043"
     CDS             77..439
                     /locus_tag="VV588_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU7084309.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            1484..2476
                     /locus_tag="VV588_002044"
     CDS             1484..2476
                     /locus_tag="VV588_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU7084310.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2478..3296
                     /locus_tag="VV588_002045"
     CDS             2478..3296
                     /locus_tag="VV588_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU7084311.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3298..4083
                     /locus_tag="VV588_002046"
     CDS             3298..4083
                     /locus_tag="VV588_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU7084312.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4181..4399
                     /locus_tag="VV588_002047"
     CDS             4181..4399
                     /locus_tag="VV588_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU7084313.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4384..4581
                     /locus_tag="VV588_002048"
     CDS             4384..4581
                     /locus_tag="VV588_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7084314.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNPQNPCQILIKKLE"
BASE COUNT         1418 a          817 c         1038 g         1676 t
ORIGIN      
        1 aacttcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttggtttt
       61 cattgagtat aacagattgt tagaagttgg tttaaatttc ctaatcagtt tgttcacatt
      121 taccttcgat atattatatc ccatagttaa ggttggtcat acagatgatt atagtcatgg
      181 agccgtaaaa cttagtgttt ctttagttga caaagatgcc atgaaaaaaa tatctgtaac
      241 tgtaatagga tattttgaaa taaatataga tgaaaatatc accgatattc tatacgtaaa
      301 tggtactgct attctttatc attatttacg ttctattgtt tcaatagttt cggcaattga
      361 tagcagtgaa gcaatgttgc tacctaccat taatgtttta gagttactag ataaatctca
      421 accttttgaa gaagaataat ttattagctc actaaattga gggtaaggaa aagtaaaatc
      481 agtaagaaaa atgtcttgca ttatacagca accttttggg aatgagtaga tggattgaat
      541 aaaattttat taagagtgga tgatttatct gtagattatt attggacagt tagtcttgaa
      601 gtagtctaag aattaggtta taatcagtag aatccttgct aataatgagg aggttagttt
      661 atgtatagta gactgaatct aaaatagtac gaaacaattg ctaaaacatt tatagaaatt
      721 aattttactt tcccaatcga tttgttctca tcttatttca atccgctata tattatggta
      781 tcgaatcttc atcagaatga taaaattaat caattgatat ctgattacaa acagaatatg
      841 aaagcttttt atatcactat tgaaaaattt atacgagatg atgaaagcct taagtgttat
      901 tttataaagg ttatttcaag tcgttccaag gtaacaagtc tagatcagat tgaagctgat
      961 aaaacgatac aaagaaaata ttcaagtgag ctaaaaaaat ttattggatt ttataatgag
     1021 attatttgtg aggaaaatag tttcctacat gtacgaaaga ggtggtcgag ttggtttagg
     1081 tagtcgatgc gtgagttgat aattctcagg gtatggactt ctttttcatg aatgaggtaa
     1141 aagagcaggt attgtttaga gacaatcatt ctgagcatat tttctggata gagggagtat
     1201 ccgattttat gatcaaagtt aataccgccc tctggtgaga agatgagtag gttggtaatt
     1261 taaactatta aacagaattt ttgattaaaa gtattatttt atgagagaaa tcctaatttc
     1321 acaatccata ggcaaactct tgcatttcgt tttttattgg actataatag gttggtataa
     1381 agccttttgt agtaataaaa tgtagaaggt gtagaaagca aggatttaga atatttgtag
     1441 ttaaaaacac aatgttgcta ttccttacga tagggagata gatatggcaa tgatagaagt
     1501 ggaacatctt cagaaaaatt ttgtgaagac tgttaaggaa ccgggcttga agggggcttt
     1561 gcgctccttt attcatcctg aaaagcagac ctttgaagcg gtcaaggatt tgacctttga
     1621 ggttccaaaa gggcagattt taggatttat cggggcaaat ggtgctggga agtcgacaac
     1681 cattaaaatg ctgacaggaa ttttgaaacc aacatctggt ttttgtcgga ttaacggcaa
     1741 gattccccag gacaatcggc aagattatgt caaagatatt ggcgtagtct ttggacaacg
     1801 cacccagcta tggtgggatt tggctctgca agagacctac actgtcttaa aagagattta
     1861 tgatgtgcca aactcgctct ttcataagcg catggacttt ttgaatgaag tcttggattt
     1921 gaaggacttt atcaaggatc ccgtgcggac tctttcactg ggacaacgga tgcgggcgga
     1981 tattgcggcc tccttgctcc acaatcccaa ggttcttttt ttagatgagc cgaccattgg
     2041 tttggacgtt tcggttaagg ataatattcg tcgggcaatt actcagatca atcaagagga
     2101 agaaactacc attcttttga ccactcacga tttgagtgat attgagcaac tttgtgatcg
     2161 gattttcatg attgacaagg ggcaagagat ttttgatgga acggtgagcc aactcaagga
     2221 gacctttggt aagatgaaga ctctctcttt tgaactgcta ccaggtcaaa gtcatctcgt
     2281 ctctcactat gaaggtctgt ctgatatgac cattgataga caaggaaaca gcctcaacat
     2341 tgaatttgat agttctcgct accagtcagc tgacattatc aagcaaaccc tgtctgattt
     2401 tgaaatccgc gatttgaaga tggtggatac ggatattgag gatattatcc gtcgcttcta
     2461 ccgaaaggag ctctaggatg atcaaattgt ggagacgtta taaacccttt atcaatgcag
     2521 gggttcagga gttgattact taccgagtca actttattct ctatcggatt ggcgatgtca
     2581 tgggggcttt tgtggccttt tatctctgga aggctgtctt tgattcttcg caagagtctt
     2641 tgattcaggg cttcagtatg gcggatatca ccctctacat catcatgagt tttgtgacca
     2701 atcttctgac tagatccgat tcgtccttta tgattgggga ggaggtcaag gatggctcca
     2761 ttatcatgcg tttgttgcga ccagtgcatt ttgcggcctc ctatcttttc accgagcttg
     2821 gttccaagtg gttgattttt atcagcgttg gccttccatt tttaagtgtc attgtcttga
     2881 tgaaaatcat atcgggtcaa ggtattgtag aggtgctagg attaactgtc ctttatcttt
     2941 ttagcttaac gctcgcctat ctgattaact ttttctttaa tatttgcttt ggattttcag
     3001 cctttgtgtt taaaaatctt tggggttcca acctacttaa gacttccata gtggctttta
     3061 tgtcggggag tttgattccc ttggcattct ttccaaaggt tgtttcagat attctttcct
     3121 ttttgccttt ttcatccttg atttatactc cagttatgat cattgttgga aaatacgatg
     3181 ccagtcagat tcttcaggca ctccttttgc agttcttctg gctcttagtg atggtgggat
     3241 tgtctcagtt gatttggaaa cgggtccagt cctttatcac cattcaagga ggttagtatg
     3301 aaaaaatatc aacgaatgca tctgattttt atcagacaat acatcaaaca aatcatggaa
     3361 tataaggtgg attttgtggt tggtgtcttg ggagtctttc tggctcaagg cttgaatctc
     3421 ttgtttctca atgtcatctt tcaacatatt ccattcctag aaggctggac ctttcaagag
     3481 atagctttca tttatggatt ttccttgatt cccaagggaa tggaccatct cttttttgac
     3541 aatctctggg cactagggca acgcctagtc cgaaaagggg agtttgacaa gtatttgact
     3601 cgtcccatca atcctctctt tcacatccta gttgaaacct ttcagattga tgccttgggt
     3661 gaactcttag tcggtggtat tttattggga acaacagtga ccagcattgt ttggactctt
     3721 ccaaaattcc tgcttttcct agtttgtatt ccttttgcga ccttgattta tacttctctt
     3781 aaaatcgcaa cagccagtat cgccttttgg actaagcagt caggcgccat gatttacatc
     3841 ttctatatgt tcaatgactt tgctaagtat ccgatttcta tttacaattc tcttcttcgt
     3901 tggttgatta gctttatcgt gcctttcgcc tttacagcct actatccagc tagctatttc
     3961 ttacaggaaa aggatgtgtt ctttaacgta ggaggtttga tgttgatttc tctggttttc
     4021 tttgttattt cccttaaact ttgggataag ggcttagatt cctacgaaag tgcgggttcg
     4081 taaaagctaa agtaagacta aaatcaagaa aggaacttat gatgtttgta attgaagaag
     4141 tcaaggatga aaatcaaaaa aggcagttgt cgctgaggtt ttgaaggatt tgccagaatg
     4201 gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac tgcaagtttg
     4261 gaccgcctat caggagagtg atttgactgg atttgtaagg ttatcctatt cgagtgaaga
     4321 ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa aattgggagc
     4381 caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct gcaggtcaaa
     4441 acagtggcag aagcttctaa taaagattat gatcgaacaa atgactttta tcgaggtctt
     4501 ggctttaaaa agttagagat tttttctcag ctatggaatc cgcaaaatcc ttgtcagatt
     4561 ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgcc atactgtaag
     4621 tgtaatcgcc gatttagctc agttggtaga gcaaggcact cgtaaagcct aggttatagg
     4681 tagataaacg actgaggagt tgaaaaaata gataggtaga agataaccgt taagccttat
     4741 tcttagcggt tatttatatt atttaatagc gctgatattt catcaattat gcctgttttc
     4801 gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga atgtgcttat
     4861 aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc ttcaaaccac
     4921 gtcaacgtcg ccttgccgtg cgtatggtt
//
LOCUS       DAVIME010000080         4299 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVIME010000080 DAVIME010000000
VERSION     DAVIME010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.080"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..733
                     /locus_tag="VV588_002049"
     CDS             <1..733
                     /locus_tag="VV588_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU7084315.1"
                     /translation="SQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVG
                     ESGSGKSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLR
                     ENLTFGHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARC
                     LLSKPSVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNG
                     EIVEIGTHRELLELGGIYKQLYSNN"
     gene            757..2496
                     /locus_tag="VV588_002050"
     CDS             757..2496
                     /locus_tag="VV588_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU7084316.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            2547..3314
                     /locus_tag="VV588_002051"
     CDS             2547..3314
                     /locus_tag="VV588_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEU7084317.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            3316..3948
                     /locus_tag="VV588_002052"
     CDS             3316..3948
                     /locus_tag="VV588_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU7084318.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
BASE COUNT         1523 a          602 c          819 g         1355 t
ORIGIN      
        1 cagtcaagat ataaaatttg ataaaaaaat agaattaaaa gatatttggt ataaatatgg
       61 attatttgat gattatgttt tgaaaggaat aaatgttact attaaaaaag gagaaactgt
      121 tgctattgtt ggagaatcag gttcaggtaa gagtacatta gctaaaattt tattaggttt
      181 attagaacct aatattggtt caatagaagt tgatggagta gaaaaagaag aaattggtca
      241 aacattgtat agaaagattt ttggagcagt gttacaaaat tcaaccctaa gttatggtac
      301 cttaagagag aatttgacat ttggacactt tgtttcagat gaagaattaa tgacaaatct
      361 aaattcaatt ggtcttagca atgtagttaa atctttacct cttggattag agacaatcat
      421 cgctgaagaa ggtaataact tttctggagg gcagcagcaa atgatacttt tagctcgttg
      481 tcttttgtcg aaaccttcgg tagttgtttt ggacgaagca acaagtagtt tagataattt
      541 atctcaacaa attacaactt cttacttaag tgaaatcggt accactaaga ttttaattgc
      601 ccatcgacta gatactatca agtctgcaga taagatctta gtaatgcata atggtgaaat
      661 tgtagagatt gggacccata gagaacttct tgaactagga ggcatttata agcaattgta
      721 ttcaaataat tagtttttga ttaaaagggt aaatttatga agattatgaa aaaaaaatat
      781 tggactttag cgatattatt cttttgtttg ttcaataatt ctgttactgc tcaagaaata
      841 cctaaaaatc ttgatggcaa tataactcac actcagacta gcgaaagttt ttctgaatct
      901 gatgaaaaac aggttgacta ttctaataaa aatcaagaag aagtagacca aaataaattt
      961 cgtattcaaa tcgataagac agaattattt gtaacaacag ataaacattt agaaaaaaac
     1021 tgttgtaaat tggaacttga accacaaata aataacgata ttgttaactc tgaaagtaat
     1081 aatttactag gcgaagataa tttagataat aaaattaagg aaaatgtttc tcatctagat
     1141 aatagaggag gaaatataga gcatgacaaa gataacttag aatcgtcgat tgtaagaaaa
     1201 tatgaatggg atatagataa agttactggt ggaggcgaaa gttataaatt atattctaaa
     1261 agtaattcta aagtttcaat tgctatttta gattcaggag tcgatttaca aaatactgga
     1321 ttactgaaaa atctttcaaa tcactcaaaa aactatgtcc ccaataaagg atatttagga
     1381 aaagaggagg gagaggaagg aataatatca gatattcaag atagattagg tcatggtacg
     1441 gctgttgtag ctcaaattgt aggggatgac aatattaatg gagtaaatcc tcacgttaat
     1501 attaacgtct atagaatatt tggtaagtcg tcagctagtc cagattggat tgtaaaagca
     1561 atttttgatg ctgtagatga tggcaatgat attatcaatc ttagtactgg acaatattta
     1621 atgattgatg gagaatatga ggacggaaca aatgattttg aaacattttt gaagtataaa
     1681 aaggctattg attacgcgaa tcaaaaagga gtaattatag tagctgcatt agggaatgac
     1741 tccctaaatg tatcaaatca gtcagattta ttgaaactta ttagttcacg caaaaaagta
     1801 agaaaaccag gattagtagt tgatgttcca agttatttct catctacaat ttcggtcgga
     1861 ggcatagatc gcttaggtaa tttatcagat tttagcaata aaggggattc tgatgcaata
     1921 tatgcgcctg caggctcaac attatctctt tcagaattag gacttaataa ctttattaat
     1981 gcagaaaaat ataaagaaga ttggattttt tcggcaacac taggaggata tacgtatctt
     2041 tatggaaact catttgctgc tcctaaagtt tctggtgcga ttgcaatgat tattgataaa
     2101 tacaaattaa aagatcagcc ctataattat atgtttgtaa aaaaaattct ggaagaaaca
     2161 ttaccagtaa aaaatggtat aaaagtgtta aatataccaa acgtattgag atatgatttg
     2221 aatatgttac aattagaata taaaaatgaa caaagttggg atagtttcat agataatgtt
     2281 aatttaattg agttggaaga gagaattcaa actactattg gaattaaaca aataaacaca
     2341 cacaatatta ttactattgc ccgagaaggg tactctcaaa attatttacc taacacttca
     2401 gaaaatacat ataattcatt acaagtcagt ttagttggag tattactact ttttataagt
     2461 atggtaaata ttttatgggc taaaaaaagt aaatgaaaat aaaatttgga gccctctgaa
     2521 aaagtaagtc ctacagttca actaaaatga gtcaaaagat gaatcacctt gatgtagggg
     2581 agtttgtctt attgctgcct gaacacctcc gttcagagga agaacattat aaatctgttt
     2641 ttgaagacga cttaaccagt cgcatatcta gtcaagatga acgacagcaa atgactgcta
     2701 cggtaggtta tttagaatca ggtcaggatc gttttgtgta taatacgacc cctatttctt
     2761 accagcagtt tttgaaagat ccaatcatca ttgttataac accccaatca actggtccac
     2821 agtccatttt gttttggata gacgcagtac agaactacgt tctctttaat caattgtctg
     2881 atgcccagga gcttatccag agacaaggca ttgaaaattg ggtctcagaa atgcaaacag
     2941 gttaccacaa ctacatcaca ttattggata atatccagag ggaacgttgg gtaatgctag
     3001 caggagctgt gcttgggatt gcaacttcaa tcttgttgtt taacactatg aataggctct
     3061 actttgaaga atttagacgt gccattttta tcaaacgcat tgcaggtctc aggttcttag
     3121 aaatccatcg cacttatctc tttgctcaac tgggtgtgtt tttactggga tttgttgcga
     3181 gtgtatttct tcaggtagag ataggagttg ctttcttagt cttgttactc tttactggtc
     3241 tatctctttt acagttacat gtccaaatgc agaaagaaaa caagatgtcc attcttgttt
     3301 tgaagggagg ttaatatgat tgaacttaaa caggtgagta aatcttttgg agaacgagag
     3361 ttattttcga atctttcaat gacatttgag gctggaaaag tctatgcctt aattggttca
     3421 agtggtagcg gaaaaacaac cttgatgaac atgattggga aattagaacc ttatgatggg
     3481 acgatttttt accgaggtaa agacttggcc aattataaat cgagtgattt tttccgtcac
     3541 gaattgggct acctcttcca gaactttggc ttaattgaaa accaaagtat tgaagaaaac
     3601 cttaagctag gtctcattgg tcaaaagttg agtcggtcgg aacagcggtt gaggcagaag
     3661 caggctttag aacaggtcgg cctggcttat cttgacctag ataagcgcat ctttgagtta
     3721 tcgggcggag aatcgcaacg ggttgccttg gcaaaaatta tcttaaagaa tccacccttt
     3781 attctggcag atgagccaac agcttcaata gacccagcaa cctctcagtt gattatggag
     3841 attttgctat ctcttcgaga tgataatagg ctaatcatta tcgcaacaca taatccggca
     3901 atttgggaga tggctgatga agtgttcacg atggatcatc tgaaataaaa atccttgttt
     3961 ttaattgcac gatgagttac tgaaatatta tcatgaatca agaattggag ttaatttaga
     4021 attgtacttt attaatattg aggtaacttt ttcttgataa aggaagaaat aatggagagg
     4081 aagttagaat gaaaaaattc gacaattata ttattgagaa gccttgcgat tctaattcag
     4141 ataaactgca aaaaatctta ataattgaaa gtttggtaga tgatattttg caattttctc
     4201 tcagaatcaa taatagtgta ggagagattt tcctcctaca accgttttaa aagaaaacta
     4261 tctttatccc aaatcattca tacctctctc aactagatg
//
LOCUS       DAVIME010000081         4196 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVIME010000081 DAVIME010000000
VERSION     DAVIME010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.081"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            229..2730
                     /locus_tag="VV588_002053"
     CDS             229..2730
                     /locus_tag="VV588_002053"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU7084319.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDTSKPKFYALDMFPYPS
                     GVGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            3030..3722
                     /locus_tag="VV588_002054"
                     /pseudo
     CDS             3030..3722
                     /locus_tag="VV588_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            3734..4150
                     /locus_tag="VV588_002055"
                     /pseudo
     CDS             3734..4150
                     /locus_tag="VV588_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1259 a          797 c          969 g         1171 t
ORIGIN      
        1 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcgtc
       61 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      121 catagtcatc aaaattaatg agatacagta tacagttttt tctttaaaca catttcaaat
      181 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttat
      241 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      301 acaggaacag atacatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      361 ggagttggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      421 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      481 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      541 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      601 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      661 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      721 gccattgcca atgaagaagt gcttcctgac ggaacttctg agcgtggagg ctatccagtt
      781 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      841 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      901 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
      961 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtctt ggctcctgaa
     1021 catgaattag tagacgctat cacaagttca gagcaagcag aagctgtagc agactataaa
     1081 caccaagcca gccttaagtc tgacttggtt cgtacagacc ttgctaagga aaaaactggt
     1141 gtttggacag gtgcctatgc catcaaccct gtcaatggta aggaaatgcc aatctggatt
     1201 gcggactatg ttcttgctag ttatggaaca ggtgcggtta tggctgtgcc tgcccacgac
     1261 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1321 ggaaatgtcg aagaagctgc ctacacagag gatggcctgc atgtcaattc agacttccta
     1381 gatggattga ataaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1441 tgtggtcagg agaaggttac ctaccgcctc cgcgactggc tctttagccg tcaacgttac
     1501 tggggtgagc caattccaat cattcattgg gaagatggaa cttcaacagc tgttcctgaa
     1561 actgaattgc cgcttgtctt gcctgtaacc aaggatatcc gtccttcagg tactggtgaa
     1621 agtccactag ctaacttgac agattggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1681 cgtcgtgaaa ctaacaccat gccacaatgg gctggttcaa gctggtacta cctccgctat
     1741 attgacccgc acaatactga gaaattggct gatgaggacc tcctcaaaca atggttgcca
     1801 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta tgctcgtttc
     1861 tggcataaat tcctctatga cctcggtgtt gttccgacta aggaaccatt ccaaaaactc
     1921 tttaaccaag ggatgatttt gggaacaagc taccgtgacc accgtggtgc tcttgtggca
     1981 accgacaagg ttgaaaaacg tgatggttcc ttctttcatg tagaaacagg ggaagagttg
     2041 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgttaaccc agacgatgtg
     2101 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgtttatggg accactcgat
     2161 gcttcgattg cttggtcaga agaaggtttg gaaggaagcc gtaagttcct tgaccgagtt
     2221 taccgtttga ttacaagtaa agaaatcctt gcggaaaaca atggtgctct tgacaaggtt
     2281 tacaacgaaa cagtcaaagc tgttactgag caaattgagt ctctcaaatt caacacagct
     2341 attgcccaac ttatggtctt tgtcaatgct gctaacaagg aagataagct ttatgttgac
     2401 tatgccaaag gctttattca attgattgca ccatttgcac ctcacttggc agaagaactc
     2461 tggcaaacag tcgcagaaac aggtgagtca atctcttatg tagcttggcc aacttgggac
     2521 gaaagcaaat tggttgaaga tgaaattgaa attgttgtcc aaatcaaagg aaaagtccgt
     2581 gccaaactca tggttgctaa agatatatca cgtgaagaat tacaagaaat cgctttagct
     2641 gatgaaaaag tcaaagcaga aattgacggt aaggaaatcg tgaaagtaat tgcggtaccg
     2701 aataaactcg ttaatatcgt cgttaaataa cgagtttatt agctctatct gccaccttca
     2761 atagtccact ggactattga agccaactaa attagttaac attgttgtga aataagatag
     2821 gaatccttca gagtagaatc tggaggattt tttgaacctt cttatgaaag tatgatatat
     2881 agtagactga atctaaaata gtacgaaaca attgctaaaa catttataga aattaatttt
     2941 actttcccaa tcgatttgtt ctcatcttat ttcaatacgc tatactatgg gcaactataa
     3001 agtttgaaaa gcgaaacaag gagaaagtta taccagtaaa cgaatatggt cagatgattg
     3061 gtgagtcaat ggaaggttat acaccaggtg aactgacttt tattgatctc ttagaagggc
     3121 gttatgctag gatagaggct ctttcagtgg aaaagcatgc ggaggatttg ctagctgttt
     3181 atggtcctga tactcctcag gagatgtgga cctacctctt tcaggagcca gtagcagaca
     3241 ttgaggaact ggtcagcctt ttaaatcaga tgttggtcgt aaggaccgtt tttactatgc
     3301 aatcatagac aaggcaactg gtaaggcttt gggaactttt tctctcatgc gtattgacca
     3361 gtaacggagt aatagaagtg ggagctgtca ctttttctcc aaaactcagg gggacacgga
     3421 tagggacaga agcccagtat ctactggctc gctatgtctt tgaagagctt aactatcgtc
     3481 gttatgagtg gaaatgcgat gctcttaacc tgccatccag acgtgctgcg gagcgtttgg
     3541 gctttattta tgaaggaacc ttccgtcagg cagtggttta taaggggcgt acgagagata
     3601 tggattggtt gtctatgatt gataaggact ggcccaaagt caaagatcgt ttggaaacat
     3661 ggttgcgtcc tgaaaatttt gataaaaatg gacagcagta caagagcttg agagagtttt
     3721 aagaggtgtt gacatgatca ctattagaaa gcaagaaatc gtcaagttcg aggatgtttt
     3781 gcatctctat caggctgtcg gttggacaaa ttatacaaat caacctcaga tgctggagta
     3841 gaccttgtat cattcattaa taatttatct ggcacttgat ggtgatgctg ttgtgggctt
     3901 gattcgtttg gttggagatg gtttttcatc agtttttgta caggatttga ttgttttgtc
     3961 tagctatcag cgccaaggga ttggtagctc cttgatgaaa caggctttag gaaattttaa
     4021 agaggcctat caagtccagc tggcgacaga acagacagaa aaaaacgtgg gatttaatcg
     4081 ttctatgggc tttgaaatct tatccaccta taattggata gggatgactt ggatgaatcg
     4141 taaaaaataa caaaacttgt tttttcttaa gcaaaattta aggatggtct agtatt
//
LOCUS       DAVIME010000082         4079 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVIME010000082 DAVIME010000000
VERSION     DAVIME010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4079
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.082"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            371..598
                     /locus_tag="VV588_002056"
     CDS             371..598
                     /locus_tag="VV588_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084320.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VV588_002057"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VV588_002057"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU7084321.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPKRENGMVHLARVEENGELTWIKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1393 a          677 c          889 g         1120 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttagatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggctcgt gtcgaagaaa atggtgagtt gacttggatc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttat ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4021 ttcaatatat tatgcgacta ttaaccttgt cttctcctaa aattgacttt cttgttttc
//
LOCUS       DAVIME010000083         3823 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVIME010000083 DAVIME010000000
VERSION     DAVIME010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.083"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..429
                     /locus_tag="VV588_002058"
     CDS             <1..429
                     /locus_tag="VV588_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU7084322.1"
                     /translation="DHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDETEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            639..3758
                     /gene="phtE"
                     /locus_tag="VV588_002059"
     CDS             639..3758
                     /gene="phtE"
                     /locus_tag="VV588_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU7084323.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNLADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1432 a          625 c          751 g         1015 t
ORIGIN      
        1 gaccatgttc gtaaaaataa ggcagaccaa gacagtaaac ctgatgaaga taagggacat
       61 gatgaagtaa gtgagccaac tcaccctgaa tctgatgaaa aagagaatca cgctggttta
      121 aatccttcag cagataatct ttataaacca agcactgata cggaagagac agaggaagaa
      181 gctgaagata ctacagatga gactgaaatt cctcaagtag agcattctgt gattaacgct
      241 aagatagcag aggcggaggc cttgctagaa aaagtaacag attctagtat tagacaaaat
      301 gctatggaga cattgactgg tctaaaaagt agtcttcttc tcggaacgaa agataataac
      361 actatttcag cagaagtaga tagtctcttg gctttgttaa aaaaaagtca accggctccg
      421 atacagtagt aaaatgaatg gagcatattt tatggagaag taacctttcg tgttacttct
      481 cttttttaga aaaacgtaac agaaacttga caaaagtaat tttaaatagt aaactattta
      541 ctggttaatt aaatggttaa ataaccggtt tagaaaacta tttaataaag taaaagaagt
      601 tgagaaaaaa cttcatcatt tattgaaatg agggatttat gaaatttagt aaaaaatata
      661 tagcagctgg atcagctgtt atcgtatcct tgagtctatg tgcctatgca ctaaaccagc
      721 atcgttcgca ggaaaataag gacaataatc gtgtctctta tgtggatggc agccagtcaa
      781 gtcagaaaag tgaaaacttg acaccagacc aggttagcca gaaagaagga attcaggctg
      841 agcaaattgt aatcaaaatt acagatcagg gctatgtaac gtcacacggt gaccactatc
      901 attactataa tgggaaagtt ccttatgatg ccctctttag tgaagaactc ttgatgaagg
      961 atccaaacta tcaacttaaa gacgctgata ttgtcaatga agtcaagggt ggttatatca
     1021 tcaaggtcga tggaaaatat tatgtctacc tgaaagatgc agctcatgct gataatgttc
     1081 gaactaaaga tgaaatcaat cgtcaaaaac aagaacatgt caaagataat gagaaggtta
     1141 actctaatgt tgctgtagca aggtctcagg gacgatatac gacaaatgat ggttatgtct
     1201 ttaatctagc tgatattatc gaagatacgg gtaatgctta tatcgttcct catggaggtc
     1261 actatcacta cattcccaaa agcgatttat ctgctagtga attagcagca gctaaagcac
     1321 atctggctgg aaaaaatatg caaccgagtc agttaagcta ttcttcaaca gctagtgaca
     1381 ataacacgca atctgtagca aaaggatcaa ctagcaagcc agcaaataaa tctgaaaatc
     1441 tccagagtct tttgaaggaa ctctatgatt cacctagcgc ccaacgttac agtgaatcag
     1501 atggcctggt ctttgaccct gctaagatta tcagtcgtac accaaatgga gttgcgattc
     1561 cgcatggcga ccattaccac tttattcctt acagcaagct ttctgcctta gaagaaaaga
     1621 ttgccagaat ggtgcctatc agtggaactg gttctacagt ttctacaaat gcaaaaccta
     1681 atgaagtagt gtctagtcta ggcagtcttt caagcaatcc ttcttcttta acgacaagta
     1741 aggagctctc ttcagcatct gatggttata tttttaatcc aaaagatatc gttgaagaaa
     1801 cggctacagc ttatattgta agacatggtg atcatttcca ttacattcca aaatcaaatc
     1861 aaattgggca accgactctt ccaaacaata gtctagcaac accttctcca tctcttccaa
     1921 tcaatccagg aacttcacat gagaaacatg aagaagatgg atacggattt gatgctaatc
     1981 gtattatcgc tgaagatgaa tcaggttttg tcatgagtca cggagaccac aatcattatt
     2041 tcttcaagaa ggacttgaca gaagagcaaa ttaaggctgc gcaaaaacat ttagaggaag
     2101 ttaaaactag tcataatgga ttagattctt tgtcatctca tgaacaggat tatccaagta
     2161 atgccaaaga aatgaaagat ttagataaaa aaatcgaaga aaaaattgct ggcattatga
     2221 aacaatatgg tgtcaaacgt gaaagtattg tcgtgaataa agaaaaaaat gcgattattt
     2281 atccgcatgg agatcaccat catgcagatc cgattgatga acataaaccg gttggaattg
     2341 gtcattctca cagtaactat gaactgttta aacccgaaga aggagttgct aaaaaagaag
     2401 ggaataaagt ttatactgga gaagaattaa cgaatgttgt taatttgtta aaaaatagta
     2461 cgtttaataa tcaaaacttt actctagcca atggtcaaaa acgcgtttct tttagttttc
     2521 cgcctgaatt ggagaaaaaa ttaggtatca atatgctagt aaaattaata acaccagatg
     2581 gaaaagtatt ggagaaagta tctggtaaag tatttggaga aggagtaggg aatattgcaa
     2641 actttgaatt agatcaacct tatttaccag gacaaacatt taagtatact atcgcttcaa
     2701 aagattatcc agaagtaagt tatgatggta catttacagt tccaacctct ttagcttaca
     2761 aaatggccag tcaaacgatt ttctatcctt tccatgcagg ggatacttat ttaagagtga
     2821 accctcaatt tgcagtgcct aaaggaactg atgctttagt cagagtgttt gatgaatttc
     2881 atggaaatgc ttatttagaa aataactata aagttggtga aattaaatta ccgattccga
     2941 aattaaacca aggaacaacc agaacggccg gaaataaaat tcctgtaacc ttcatggcaa
     3001 atgcttattt ggacaatcaa tcgacttata ttgtggaagt acctatcttg gaaaaagaaa
     3061 atcaaactga taaaccaagt attctaccac aatttaaaag gaataaagca caagaaaact
     3121 caaaacttga tgaaaaggta gaagaaccaa agactagtga gaaggtagaa aaagaaaaac
     3181 tttctgaaac tgggaatagt actagtaatt caacgttaga agaagttcct acagtggatc
     3241 ctgtacaaga aaaagtagca aaatttgctg aaagttatgg gatgaagcta gaaaatgtct
     3301 tgtttaatat ggacggaaca attgaattat atttaccatc gggagaagtc attaaaaaga
     3361 atatggcaga ttttacagga gaagcacctc aaggaaatgg tgaaaataaa ccatctgaaa
     3421 atggaaaagt atctactgga acagttgaga accaaccaac agaaaataaa ccagcagatt
     3481 ctttaccaga ggcaccaaac gaaaaacctg taaaaccaga aaactcaacg gataatggaa
     3541 tgttgaatcc agaagggaat gtggggagtg accctatgtt agatccagca ttagaggaag
     3601 ctccagcagt agatcctgta caagaaaaat tagaaaaatt tacagctagt tacggattag
     3661 gtttagatag tgttatattc aatatggatg gaacgattga attaagattg ccaagtggag
     3721 aagtgataaa aaagaattta tctgatctca tagcgtaagg aatagcagta gaaaaagtct
     3781 gaatcaaaaa tgaagttctc tcaaaagtta gaaataaaac tct
//
LOCUS       DAVIME010000084         3340 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVIME010000084 DAVIME010000000
VERSION     DAVIME010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.084"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(207..818)
                     /gene="rpsD"
                     /locus_tag="VV588_002060"
     CDS             complement(207..818)
                     /gene="rpsD"
                     /locus_tag="VV588_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU7084324.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1013..2065)
                     /locus_tag="VV588_002061"
     CDS             complement(1013..2065)
                     /locus_tag="VV588_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU7084325.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2062..2760)
                     /locus_tag="VV588_002062"
     CDS             complement(2062..2760)
                     /locus_tag="VV588_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU7084326.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2927..>3340)
                     /locus_tag="VV588_002063"
     CDS             complement(2927..>3340)
                     /locus_tag="VV588_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEU7084327.1"
                     /translation="ATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPS
                     NSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLP
                     NTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          933 a          747 c          635 g         1025 t
ORIGIN      
        1 gaaaatctat tgaatattcc ataaaagatt ataccacatt gtgtactatt tttggttcat
       61 tttactatat cactttggac tatatcggtc tagttatgtc taaacgatta tagctggata
      121 ctaagagaaa tcaaaaaagc actaagggag aacgtcccaa agtgcttagt ttcaaggctt
      181 tacagcctat cttatttaat aaaatattac aacattttgt tgtagaattc aacgacaagt
      241 gcttcgttga tttctgggtt gatttcgtcg cgttctggca agcgagtcaa tgaaccttcc
      301 aatttttcag cgtcgaatga tacgaatgct ggacgtccaa gagtagcttc tactgcttca
      361 aggattgctg gaactttcaa tgatttttca cgaactgaga tcacttgacc tggagttacg
      421 cggtatgatg ggatatcaac gcgtttcccg tcaacaagga tgtgaccgtg gtttacaaat
      481 tgacgagctt gacgacgagt agtcgcgaga ccaagacggt aaacaacgtt atccaaacga
      541 cgttccaaaa gaagcataaa gttgaaacct aggattccgc ctttgatttt tgtagcttgt
      601 acaaacaagt tacggaattg tttttcacct acaccgtaag tgaaacgaag tttttgtttt
      661 tcagccaatt gcaaaccgta ttctgacaat ttagaacggt tgtttggtcc gtgttgtcct
      721 ggtacgtagt tacgacgtgc caattcttta cctgtacctg taagtgaaag gccaaggcga
      781 cgagcttgtt tccaagatgg tcctgtataa cgtgacatat gaatgtcctc ctgatataaa
      841 taatatttcg gtggaaatag tcacttagaa agccctgatt cgtgcagatg cccttcgcct
      901 aaacagccaa ggttacttat cataagacac ctgttgacga gcttcatgct ttcctgctga
      961 tatttcacac aaaattcatt ctaccatgaa tagctggatt tgtaaagggg ttttaggctt
     1021 tattttcact accagagagg ttgagaacga gagtaaaggt acttcctaga ccgtactggc
     1081 tgctgactgt gatttcccca cccaattgat gggccaattc acgcgcaatc gcaagtccta
     1141 atccatgacc acctgtcttc atgttacgcg aagtttcgac acgataaagg cgtttgaaaa
     1201 tattttccaa atcctctggg gcaatgccct gcccttcatc ggtcacactg attgaaagct
     1261 ggcccttctc cagcttagcc accacttcca gcttggttcc tggagcagaa tatttaaaag
     1321 cgttatcgac cagattcacc aagatacgag aaagcttagc ataatctccc tcaatccggg
     1381 cagactctgg gattacctgc aagtggacat ctcttctctc ctgctcaatc aaaaactgaa
     1441 attcactcat gcactcaatt aagagcttgt ccagaaaaat actgtcttta ctggtagttt
     1501 ccacctgatt tctagctgtg tttagggtca aaaaattcaa ctcctcaacc agtttattga
     1561 gcctctccgt ctggcgtcca atggttgcta gataatgagc ttgctccgac tccttgataa
     1621 tcccatccaa aatcccttct accgtcgctt ggatcgaagt gataggagtc ttaatatcat
     1681 gcgacaactg agcaatcatc aagccctttt ctcgttcgct ttcttccaag gaatcaaagc
     1741 ttacctgcaa atcatgggac atctcattaa aagtttgccc taattgctga aattctacag
     1801 gaccttgaac ctccaaattt gaaggaaaat ccttggccgc tacccgcttg gcatgctcct
     1861 tgagtttgcc caacgacgta aagactggca ataggagaaa gagactaatc ccagcaccga
     1921 caaggctggc aacgatggtc atcccaagca aaaagtaaat ctcgcctttc gcaatcagca
     1981 ttttttgaac agcccaaaaa acaaccaaaa tggttaagag ggttgaaata atatatccaa
     2041 ccaaaatata actttttagt ttcatgtttg tcctctcggt ttctctatct tatatcccaa
     2101 cccccaaact gtcttaatag tgggcgtttg gtcactacta tattttgcca gctcctgtcg
     2161 aagagcatgg atatgcacat tcaaggtatt ggtgtcatcc acgtagtctt ctttccagat
     2221 cttttcatag aggtctgtct tggagaaaac tcgctctgga ttgctagcta aaatccacag
     2281 caattcaaat gatttaacag ttaaatccag catttcttct cctatttgaa cttcatgact
     2341 actatgattc atttttagat tgccaaggga aatcagctct gtttcgcccc cacgatgaag
     2401 gcggcgcaaa atattgtgga cacgcaaaac tagctcacgt gggctaaaag gcttagcaat
     2461 aaaatcatct gctcccaagc tcaggccgta aatcttgtcc tgctcactgg tcttagcagt
     2521 aataaatagg aaaggctgct ctggtgataa gtattgaacc tcactgatta aatcataacc
     2581 atccatccga ggcatcatga catctgtgat aatcaaatca atcggttttt tcttgaacag
     2641 ctctagcgct tccagtccat catgggctac caagacctga taacctgcct gaattaagta
     2701 tctctgatga atatctgtga tttctacctc gtcgtcaacg agtaaaattg tctttcccat
     2761 ctgtctctcc tttgataaaa acagtgctat actgctttaa gtataacact atttttattg
     2821 ttttacgatg attttaatct gctattgaaa gaaagtcctg attgctgatt gagttgttaa
     2881 actaatctta gtcagcccac tatccatcat ttatttcctt agctgattag ttttcttctt
     2941 ttttgttttt caaacctaga ccaccgagta aacctgcaag cgcaagccca aggaaaccaa
     3001 tacttgccat tgatgtttga gtctcaccag tatttggtag catagcttta tcctctgaca
     3061 tcatcgtatc agacatcttg ttagcagaag cagccatatt ttcacctgcc atcgtgttgg
     3121 tagaacttgt catggtgtca gcaggcatgc tatctgtagt acctgtagca tgattgtgat
     3181 tcatcggagt cacgccagaa ccagagttag aaggtgataa tgaaccattt gctgtgtctg
     3241 atgtttcttt aacatttatc ttaatagtga cttttttagt tgctacgatg ttgtccaagt
     3301 ctggtttacc gtctttgtta ccatagacat tgactgtagc
//
LOCUS       DAVIME010000085         3270 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVIME010000085 DAVIME010000000
VERSION     DAVIME010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3270
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.085"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            114..278
                     /locus_tag="VV588_002064"
     CDS             114..278
                     /locus_tag="VV588_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU7084328.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            362..928
                     /gene="amaP"
                     /locus_tag="VV588_002065"
     CDS             362..928
                     /gene="amaP"
                     /locus_tag="VV588_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU7084329.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSNLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            940..1110
                     /locus_tag="VV588_002066"
     CDS             940..1110
                     /locus_tag="VV588_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU7084330.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1149..1757
                     /locus_tag="VV588_002067"
     CDS             1149..1757
                     /locus_tag="VV588_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU7084331.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1788..1991
                     /locus_tag="VV588_002068"
     CDS             1788..1991
                     /locus_tag="VV588_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU7084332.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2102..2374)
                     /locus_tag="VV588_002069"
                     /pseudo
     CDS             complement(2102..2374)
                     /locus_tag="VV588_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2683..2970
                     /locus_tag="VV588_002070"
     CDS             2683..2970
                     /locus_tag="VV588_002070"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU7084333.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
BASE COUNT         1128 a          508 c          617 g         1017 t
ORIGIN      
        1 aaattgattt tttgatatta aaataaaaaa ggagggtagg cagtgttgtg atcaattatt
       61 gctggaggtc ttattggtct cttggcaggt aaaatcacta aaaaagtagt tctatgggaa
      121 tcatcgcaaa tgtattcgct ggtttagtcg gggcatatgc aggacaatct cttttaggta
      181 gttggggtcc atcaatcgct ggaatggctt tgctcccatc tattgtaggt gcagcgattg
      241 tgattactgt agtgtcattc tttacaggta gaaagtaaac ttttcgccag taaagttagc
      301 aaactatttt taaatcaatg acgggaaaaa tagtttaaat gttaaatcga aaggattgta
      361 tatgtcaaaa gcaaagaaaa tatgtttcat tattttctgt attttaatct tgacaatttt
      421 ccttcctgtt ttgatagatt atcatcaagt tagtaatcta ggtattcatc tacttagctg
      481 gagacagaac tccgtagttg aattctatct tgctagatat gtcttttggg ggacagtggt
      541 tctatcaact ttagttttat tatccatttt agttgtgatg ttttatccta aacgttactt
      601 ggaaatccaa cttgaaacta aaaacgatac attaaaatta aagaattcgg caatcgaagg
      661 ttttgttaga agtttggtga gtgatcatag attgatcaag aacccaactg ttcatgtaaa
      721 tttacgaaaa aataaatgtt tcgttcatgt agaaggtaaa attcttcctt cagacaacat
      781 cgctgacaga tgccaaataa ttcaaaatga aataactaat ggattgaagc agttttttgg
      841 tattgagcgt caagtaaaac ttgaagttgc agtaaaaaat taccaaccaa aacctcaaaa
      901 caaaaagact gttagtcgtg tgaagtaagg aagtaaaaaa tggaatggct taaacaatat
      961 cgatatccaa ttatcgctgg tctcataggc gtatttctgg cttgtttgat tgtctccttt
     1021 ggcttcttca aaacaatatt tgtattgatt ttaggagcac tgggagttgc agctggatta
     1081 tatatcgaaa aaaactatat agataaataa aaaaataaaa attactaatt taattaaagg
     1141 agtttcatat gtcaaacgaa aaaaacacaa acactaacgt agaaaagaaa gatgctactg
     1201 ttgtagctca cgaaatcaaa ggggaactta cttacgaaga taaagttatc caaaaaatca
     1261 ttggtctttc actagaaaac gtttcaggtc ttttgggaat cgatggtggt ttcttctcaa
     1321 atcttaaaga aaaaatcgtt aacagcgatg acgtaacaag tggtgttaac gtagaagttg
     1381 gtaaaacaca agttgcagtt gacttaaacg ttattgttga gtaccaaaaa aatgttccag
     1441 ctttatattc agaaatcaga gaaatcgtat cttcagaagt tgctaaaatg actgacttgg
     1501 aaattgttga aatcaacgta aacgttgtcg acatcaaaac taaagaacag catgaagcag
     1561 actcagtaag ccttcaagat cgcgtatctg acgttgctga atcaacagga gaattcactt
     1621 cagaacaatt cgaaaaagct aaatctggtc ttggatctgg tttctcaact gttcaagaaa
     1681 aagttagcga aggtgtagaa gctgttaaag gtgcagcaaa tggtgtagta tctcacgaaa
     1741 acactcgtgt aaactaagat aaaataaata taacaggaga aattatcatg tcagtagaag
     1801 aaaaattaaa tcaagctaaa ggttctatta aagaaggtgt tgggaaagcc atcggtgatg
     1861 aaaaaatgga aaaagaagga gcagctgaaa aagttgtttc taaagtaaaa gaagttgccg
     1921 aagacgctaa agacgctgta gaaggtgctg tagaaggtgt taaaaacatg ttgagtggcg
     1981 acgataaata aggttaaaag ttactttatc ttttttggta acattagtca aaagagtctg
     2041 agtcaagatg attctcagaa aacaaaaagc tagagattcc caattgcgga actctagctt
     2101 tttaattttg cctctttctc ttattatatt tcagcaggtt gttggccatg agtatgaatc
     2161 ccatgtcaat tctcacttga cgcttacctc tcagatgaca tctcttataa cccaaacaaa
     2221 cctttatctg cccaaagaca gatttcatat caatcttacg tttagcgaaa atttgtctac
     2281 ccttggaaga taaaagtgcc tgatattctt tagtttttaa acactggtaa cgttcattca
     2341 tatacagtcc cttttgaggg gctgattcag gttcataatc gcagtcaaca ttgatttcaa
     2401 ggctgtttgc tttctatctc ccctttttca taatgtatag taaaatgaaa taataacagg
     2461 acgaatcgat cgggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact
     2521 attctagttt caatctacta tattttcgta caggtgcttc aatagtttct atagtaaaat
     2581 gaaccaaaaa tagtacacgt tgcggtataa tgttcttgtg gcatattcat tagattttcg
     2641 taaaaagttc tctcctattt gtgagcgaac aggtatagtc aattgattgt cagtttgaag
     2701 accaagagtc gtaaggcaaa ggatatggca gaatccatcc aagggtggct ggcacaattt
     2761 ctagtgaacc tctttaaatc tattacgttt gactgtggaa aagagttttc aaaatggaaa
     2821 gatatttcca atcatcacga tagtgagagc ttttttgcga atctaggatg tccaagacag
     2881 cggtgtctca acgaacattc aaatagactt ttaaggtgtc atgacttgcc aaagcagaca
     2941 gatttcaacg aagtcagtca agaattttag gctgggtaaa aactcaattt caggagaaaa
     3001 tgaaataaat attcccacaa taaaacgcat agtatcaaag tttttccaac acctgatatt
     3061 atacattttt taattttaaa gactttttcc cagcctcaag aaatcacatc ccacctaaat
     3121 cctttggata ccaaatacct catcaggtat tttctgagtt ggtaagactg tctagcttaa
     3181 tttgacaaat ggagggcgtt aaatccagtt tttacaggaa gtctatttaa atattttcac
     3241 actgacctta caaaatatga aataaattat
//
LOCUS       DAVIME010000086         3124 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVIME010000086 DAVIME010000000
VERSION     DAVIME010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.086"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            53..2233
                     /locus_tag="VV588_002071"
     CDS             53..2233
                     /locus_tag="VV588_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU7084334.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2285..3100
                     /locus_tag="VV588_002072"
     CDS             2285..3100
                     /locus_tag="VV588_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU7084335.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
BASE COUNT          913 a          589 c          688 g          934 t
ORIGIN      
        1 gtgcaaacgt tttcgtaaaa cgtttgccta aataaaaata aaggagattt gaatgatgaa
       61 agatacattc aaaaatgtct tgtctttcga attttggcaa aaattcggta aggctttgat
      121 ggtagttatc gcggttatgc cggctgctgg tttgatgatt tcaatcggta agtctatcgt
      181 gatgattaac ccaacctttg caccacttgt catcacaggt ggaattcttg agcaaatcgg
      241 ttggggggtt atcggtaacc ttcacatttt gtttgcccta gccattggag gaagctgggc
      301 taaagaacgt gctggtggtg ctttcgccgc tggtcttgcc ttcatcttga ttaaccgtat
      361 cactggtaca atctttggtg tatcaggcga tatgttgaaa aatccagatg ctatggtaac
      421 tactttcttt ggtggttcaa tcaaagttgc tgattacttt atcagtgttc ttgaagctcc
      481 agccttgaac atgggggtat tcgtagggat tatctcaggt tttgtagggg caactgctta
      541 caacaaatac tacaacttcc gtaaacttcc tgatgcactt tcattcttca acgggaaacg
      601 tttcgtacca tttgtagtta ttcttcgttc agcaatcgct gcaattctac ttgctgcttt
      661 ctggccagta gttcaaacag gtatcaataa tttcggtatc tggattgcca actcacaaga
      721 aactgctcca attcttgcac cattcttgta tggtactttg gaacgtttgc tcttgccatt
      781 tggtcttcac cacatgttga ctatcccaat gaactacaca gctcttggtg gtacttatga
      841 cattttaact ggtgcagcta aaggtactca agtattcggt caagacccac tatggcttgc
      901 atgggtaaca gaccttgtaa accttaaagg tactgatgct agtcaatacc aacacttgtt
      961 agatacagta catccagctc gtttcaaagt tggacaaatg atcggttcat tcggtatctt
     1021 gatgggtgtg attgttgcta tctaccgtaa tgttgatgct gacaagaaac ataaatacaa
     1081 aggtatgatg attgcaacag ctcttgcaac attcttgaca ggggttactg aaccaatcga
     1141 atacatgttc atgttcatcg caacacctat gtatcttgtt tactcacttg ttcaaggtgc
     1201 tgccttcgct atggctgacg tcgtaaacct acgtatgcac tcattcggtt caatcgagtt
     1261 cttgactcgt acacctattg caatcagtgc tggtattggt atggatatcg ttaacttcgt
     1321 ttgggtaact gttctctttg ctgtaatcat gtactttatc gcaaacttca tgattcaaaa
     1381 attcaactac gcaactccag ggcgcaacgg aaactacgaa actgctgaag gttcagaaga
     1441 aaccagcagc gaagtgaaag ttgcagcagg ctctcaagct gtaaacatta tcaaccttct
     1501 tggtggacgt gtaaacatcg ttgatgttga tgcatgtatg actcgtcttc gtgtaactgt
     1561 taaagatgca gataaagtag gaaatgcaga gcaatggaaa gcagaaggag ctatgggtct
     1621 tgtgatgaaa ggacaagggg ttcaagctat ctacggtcca aaagctgaca ttttgaaatc
     1681 tgatatccaa gatatccttg attcaggtga aatcattcct gaaactcttc caagccaaat
     1741 gactgaagta caacaaaaca ctgttcactt caaagatctt actgaggaag tttactcagt
     1801 agcagacggt caagttgttg ctttggaaca agtaaaggat ccagtatttg ctcaaaaaat
     1861 gatgggtgat ggatttgcag tagaacctgc aaatggaaac attgtatctc cagtttcagg
     1921 tactgtatca agcatcttcc caacaaaaca tgcttttggt attgtgacgg aagcaggtct
     1981 tgaagtattg gttcacattg gtttggacac agtaagtctt gaaggtaaac catttacagt
     2041 tcatgttgct gaaggacaaa aagttgcagc aggagatctc cttgtcacag ctgacttgaa
     2101 tgctatccgt gcagcaggac gtgaaacttc aacagtagtt gtcttcacaa atggtgatgc
     2161 aattaaatca gttaaattag aaaaaacagg ttctcttgca gctaaaacag cagttgctaa
     2221 agtagaattg taatatactt gaggttggaa gctgtattcc aacctcttat tttgggagaa
     2281 aagaatgaaa tttttaacac tcaatactca tagttggatg gagaaagaag cagaggaaaa
     2341 attccagatt ttgcttgaag atattcttga aaaggactat gatttgattt gtttccaaga
     2401 aattaatcag gagatgacct cgtcagaggt ggaggttaat gacctttatc aagctttgcc
     2461 agcagctgag cctattcacc aagatcacta tgttagactc ttggttgaaa agttatctga
     2521 gcaagggaaa aattactact ggacctgggc ctataaccat atcggctatg accgctacca
     2581 cgaaggtgtg gctatcttgt ctaaaacacc tattgaagcc agagaaattt tggtttcaga
     2641 tgtggatgat ccaacagact atcatactcg ccgtgttgcc ctagctgaaa ctgtagtcga
     2701 tggcaaggag ctagcagttg ccagtgttca tctctcttgg tgggataaag gttttcaaga
     2761 agaatgggca cgatttgagg ctgtcttgaa aaaattgaac aagccacttt tactagctgg
     2821 agattttaac aacccagcag gtcaggaagg ttaccaagct attttagcta gtccattagg
     2881 cttacaagac gcatttgaag ttgctcaaga gaaaagtggt agctatactg ttccgcctga
     2941 aattgatggc tggaaaggga acactgaacc ccttcgaatc gattatgtct ttactaccaa
     3001 agagttagcg gtggaaaatt tacatgtcgt atttgatggt aacaagagtc cacaagtgag
     3061 tgatcactat ggcttgaatg ctatgttaaa ctggaaataa taactgaaaa gaggttggaa
     3121 ctat
//
LOCUS       DAVIME010000087         3110 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVIME010000087 DAVIME010000000
VERSION     DAVIME010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3110
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.087"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..184
                     /locus_tag="VV588_002073"
     CDS             <1..184
                     /locus_tag="VV588_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU7084336.1"
                     /translation="EYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSG
                     VTLITGKNGTGKSTLL"
     gene            complement(550..1860)
                     /locus_tag="VV588_002074"
     CDS             complement(550..1860)
                     /locus_tag="VV588_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU7084337.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGKTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2097..2969
                     /locus_tag="VV588_002075"
     CDS             2097..2969
                     /locus_tag="VV588_002075"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU7084338.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFKRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALDDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          959 a          518 c          707 g          926 t
ORIGIN      
        1 agagtatgaa aacagaactg tttcttttgc tattagttca aaaggagaaa aaatgaaagt
       61 agaaaatatt tcgtataggg tggatcatcg tatattgttt gataatattt cttttgatac
      121 ttcgagttca ggcgtgacat taattactgg taaaaatggt acaggaaagt caactttact
      181 atagtagatt gaaactagaa tagtacacat ctacttctaa aatattgtta gaaatcgatt
      241 tgactatcct gatctatttg tcctgttctt atttcatttc actacatctc aaattgagta
      301 tgacgaagtg cgctcccatg tcctgggaac gcactttctt catatttttc atattcttga
      361 atccatcgat aaagactatt gggatgaatt tttaaagttg aactaatcat ttttacagga
      421 tgaggtttac agcagagagt ttgaaggctt tatcaaaggt ttttcttggc ataatgactt
      481 ttcctcgttt ccacttaatt ttgtgtctac tttattatac caagtccacc cttaagttag
      541 ataataaatc taacttaagg aagctagaag gatgagaatc caggtggtca agagtcccaa
      601 acttaagctg atggggacac ccagaataat ttgctttttg aaggcaaggc cacgttcctc
      661 tatattggga agtgagagtt gaatgagaga accagctgat gaaaagggtg agatattagt
      721 agatagagcg ccaataacgg tggctgttgt gagtaagtga atatcaatct ggggattttg
      781 agcactgatg atagcaatga tgggaaagag ggctggagct acaacggata gggtggaact
      841 aaagagtgac atcactccgg ctatcacaca aaagaacaga ggtaaccaga aatgaggaat
      901 ggatgttgtc atgaggtgcc ctatcagtgt gactaaacct gacttgaccg ctagagacat
      961 tagtaagctc atgccgcaga gcatgataat tgtagcccag ggaaccttag ctaaaatggc
     1021 ttcttgcttc cctaatttga gccttaaggc gaggcagacc atgagtattg agacaaagcc
     1081 aatatcaaat gttttttgat aagtagctat ccaggcgatg tttgggaaaa tgagatgcaa
     1141 caagggaaaa agccaaacca aaaccatgct gctgatcatg agcaaggtgg tttgtctttg
     1201 aaccttgctg aggagtggtg gttggtcaat agtcaaggat gagtttgttt ttcccttact
     1261 atagtgactg taacaggata ataaaagcaa gacgatgagt gggtagataa tgctgacgat
     1321 aaagatatga ttgccaagtg aaaaagcttg ctcttcccat cccatttgct taaacaggcc
     1381 ttgaaagaca atgcctgagc tactggttat caaattagcc cctcctgaag ctccccaatt
     1441 gacggcttga gctccaatca aagggtgttt gtccgctttt tgacagaggg taatcgctag
     1501 aggacagcaa acggccatag tagtgaaaaa tccagcacct aaagcagaca aaagggttgc
     1561 catcaggtat aaaatcatgt agagggcgtt agggtaggtg cgtgtgcggt agagaatgtg
     1621 ttgagccaaa acatcaagag taccgttagt tattgcaaag ttataaaaga gagagacgct
     1681 aaaaatggta aaaaagagtg aggttggcca aaaatgaaga agttctttgg ggcttaatcc
     1741 catgagagtg gttgcgatga ggtaagaaaa agcaatagcc agcaggccaa tattgatttt
     1801 ggtgcggtaa ccaattccaa tggctagagc aatggcgcta atcattatta aatgaatcat
     1861 tgaattgtcc tttcagttag aatatggaaa taggttggca attttggcgc tcaaaagacc
     1921 acctgtttcc tattggtact tgactattat acacaaaaaa aatacaattg tcttgacaat
     1981 tgtattgaca cttgttagaa ttaaaaatga ggtattcagg cttgtgattt cctatggaag
     2041 ttaatagtga ttgcctctaa tgcttacaag tgatattaaa aatagaggac ttagtgatgt
     2101 caatcatttc aactgattta accccttttc aaatagatga tacattgaaa gcagccttgc
     2161 gagaagatgt tcattccgaa gattacagta ccaatgccat ttttgatcat catggccaag
     2221 ccaaggtgtc gctttttgcc aaggaagctg gtgttttagc ggggctaacc gtttttaaaa
     2281 gggtttttac cctatttgat gccgaggtga ccttccagaa tcctcatcaa tttaaggatg
     2341 gggatcgttt gactagtggc gatttggttt tagaaatcat aggctcggtg agaagtctct
     2401 taacatgtga acgcgttgcc ttgaattttt tacaacattt atcagggatt gcttcgatga
     2461 cagctgctta tgtagaagcc ttagacgatg attgcattaa ggtatttgat actcgaaaaa
     2521 ctactcctaa tttacgtctt tttgagaaat atgccgtgag agttggcggt ggctataatc
     2581 atcgctttaa tttatcagat gctatcatgc taaaagacaa tcacattgcg gcagtaggta
     2641 gtgttcaaaa ggcaattgct caagcgcgtg cctatgctcc ttttgtgaaa atggtcgagg
     2701 tggaagtgga aagccttgct gctgccgaag aagctgcggc ggcgggtgct gatattatca
     2761 tgttggataa tatgtcattg gaacagattg aacaggccat taccctaatt gcaggacgtt
     2821 ctcggattga atgttctgga aatattgata tgaccactat tagccgtttt cgtggtttag
     2881 cgattgatta cgtctccagt ggtagtttaa cccatagtgc taagagtctt gatttttcca
     2941 tgaaggggtt aacctacctt gatgtctaag ttgtaaaata aactaacttt ttaaaggatg
     3001 tctttcctct agaacgagtt ttatgtcaga tagtttaaac gcctcttcaa atatagtaaa
     3061 atgaaccaaa aatagtacac aatgtggtat aatcttctta tggcatattc
//
LOCUS       DAVIME010000088         3057 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVIME010000088 DAVIME010000000
VERSION     DAVIME010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.088"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(100..585)
                     /locus_tag="VV588_002076"
                     /pseudo
     CDS             complement(100..585)
                     /locus_tag="VV588_002076"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(623..955)
                     /locus_tag="VV588_002077"
     CDS             complement(623..955)
                     /locus_tag="VV588_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU7084339.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(968..1741)
                     /locus_tag="VV588_002078"
     CDS             complement(968..1741)
                     /locus_tag="VV588_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU7084340.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAN
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(2188..2943)
                     /locus_tag="VV588_002079"
                     /pseudo
     CDS             complement(2188..2943)
                     /locus_tag="VV588_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
BASE COUNT          978 a          564 c          402 g         1113 t
ORIGIN      
        1 ggtcaacttc gtatcaaaaa catttttttg tatttccaca tagcatcaat catttagtac
       61 aatattttaa aaacaatatc ttaacagaga aaatgatatt taatctatca gctcatttaa
      121 tcgtttttga aaatataaag caatactttt agattcaata aactcaaaat attttatgac
      181 attgtccatt tgtttaattc cagattcttt agattctgtc aggtatattt tatatccttc
      241 tacaaatttg aatgtagatt tttcaaaaac ttttgtgtca tcttttaata atttttgtaa
      301 tttcatttca aagtagtctg catatattag atgtgaattt tcaaggcaac agaaccaaaa
      361 atttaaacaa gctgacacaa ctaaatgtct attcttgccg attttttcgt aataatgtgt
      421 acgctctagt atttcttttc cgaccatgta aatataatct atttcaaaaa gatgatataa
      481 attaccaatc agcgttatct cataggactt ccatcgttcc ttctggaata aatagtcata
      541 tactaaattt agatcatctc tactaactac atgattacaa tctagctgat ttcataatcc
      601 ctgaaccata attgtattta ttttatgagt ttttcccact cttctcaaaa agtttttgtt
      661 gcttattttt tattacctcc aatcctttaa tattcaaact ataaaaattt ggagataaat
      721 taaccaaaaa atcatcacgc tccgatcttt tataatgttc taagtgatta caaaaattct
      781 ctatcgaaac attgatattt gataataatt caaaaaatgt tgaaagagaa atttcatttt
      841 ctcccctttc aaatctagaa agttgagatt ttgatataga atcagctgca gcatactcta
      901 aagaatatcc gtttaatttt ctaaaatatc gaaaagcttc tccgtaattt ttcacacttt
      961 cattccctta actttctttt cgagcgataa acataccata ttctttagga atgatcaaca
     1021 taccattatt aaactcactt tccaatcttt tacgtattat ttcctcttct agtgaaccta
     1081 tttctgaaat tcctttaaac gattggatgt atttaactag gtcatctata ctagttacct
     1141 gtaactcatc atcatagagt aatgtatcga cagagttaaa atacctactc aggtaccttt
     1201 taccattttg taaagtaaac gttctatttt ctaaatcttg attaacctca tctttaaata
     1261 aatttgccaa ataatttaca actccatttt caccaaatgt agcacagtaa aaaattcctc
     1321 cggtttttaa gaccctattc acctcagaga gagctttagg aatatcattc acatgatgta
     1381 gaagcatatt agcaataaca atatcaaaag tttcattctc aaaagaaatc ttttgaatat
     1441 ccattatctc ataattgaca ttgtttctat ttccaatcac tgacttcgtt gattttacca
     1501 tatctttaga aaaatctgta acaatcaact gcttcatttt atctatagaa tcactattac
     1561 ttttccacaa ttctcctgta ccacatccca attctagaac ctttacttca tcagtgattt
     1621 ggtagttaga aaatatccaa ttattaaatc ccaatttatt ttttgaatac ttcttatgca
     1681 attctactcg aatatcaaga ttatcatgac ttttatattg ttcaattact ttatcaatca
     1741 ttttaaatga cctccactct ataatttggc attatatcac aagaataaag atagtgttaa
     1801 ataagttgta taaatgcaaa aaaggaatat tccgttatag cagagttgta acacatttct
     1861 ataaagaaat ttattcctac gactcagttt ggcatgctta acttcctaac tcaaaaacaa
     1921 agcatcgatt aatttatccg ttcttctttt gaaacagatt tgaactgata attgctcgtt
     1981 ttaatttaag aagctctttt gagcaaaact tcattttttt aagagtccaa caatttctgt
     2041 ctatcgcttt tctactagca aaaaaaacta ccttgaggca agttttcatt tatatatcta
     2101 atttcgtaat agtatagtaa aatgaaataa ggacagtcaa atcgatttct aacaatgttt
     2161 tagaagtaaa ggtgtactat tctagtttca atctactata aatttgatat gagaatagtc
     2221 tttctcaaca tccttaccca acaagaatgc tgtagcgtcc ttcttaactt gaaccaggtc
     2281 aatattctgg gcttgggctg catagacgca gccacaataa cattgacgat agatatcata
     2341 ctcctcacac atctctactg aacgtttgta gccttgattt ttcttgaaat cgttgggaag
     2401 atagtgggtc gtgtaaattt tttgcacatc gattccgatg ctgttgatgg tttgagaatt
     2461 cttatgagga ctgatggtca aggctgaacc aaagtagtca aagcccaagt ccatagccac
     2521 ttgcgctgtt ttatccagtc ggtagtcaaa acaaaccttg caacggtcgc caccttcggg
     2581 ctcctcctct agtcccctaa ctagttttcg gtattaattg ggttcgtagg gagcttctag
     2641 gtactgaacc gtatttcctg tccgctcatt aaaatcacta acaaatttct tgatgacata
     2701 gacccgctta tggtattcta ccttgggatg gatattagaa ttggcaaaat agatggtcac
     2761 atctgcatac ttggtcaaat attctagtgt ataggtacta caaggggcac agcaaacatg
     2821 cacgagaatg gttggccgct gctcattttt ctcccatgct tgtaccattt tctgcatgac
     2881 acggtcataa ttaatcttct gattgggggg catcttgcac agaatttctt ctacatcgat
     2941 catgttcttc tcctttttct agtcttattt tatcatataa gttaggagag ctcaaatcaa
     3001 tttagaagtg aatattataa aaagaagggt tagtcattcc ctccttttgt gtttttt
//
LOCUS       DAVIME010000089         2837 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVIME010000089 DAVIME010000000
VERSION     DAVIME010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.089"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VV588_002080"
     CDS             complement(7..1362)
                     /gene="rlmD"
                     /locus_tag="VV588_002080"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU7084341.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1400..2176
                     /gene="recX"
                     /locus_tag="VV588_002081"
     CDS             1400..2176
                     /gene="recX"
                     /locus_tag="VV588_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU7084342.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQVSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2265..2798
                     /locus_tag="VV588_002082"
     CDS             2265..2798
                     /locus_tag="VV588_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU7084343.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT          897 a          523 c          518 g          899 t
ORIGIN      
        1 ccttttttaa acttttttta ttaattttac aacagcttca gttcgagctg tatgtgggaa
       61 catatcgacc gactggatat aatgaagatc atagacttct actaagcgta ccaaatcacg
      121 agccaaggtc gaaacattac aagaaatata aaccattttt tctggtacat aagtaagaat
      181 agtatctaat aacttatcat ccagacctgt acgtggtggg tcaacaatca aagcatctgc
      241 tcggtagcct tccttgtacc aacgaggaat aatctcttct gccgttccag cttcataatg
      301 agtattgtca aatcccattc ttttagcatt tcgcttggca tcttcaatag cttctggaat
      361 aatatccata cctctgagtg tttttacttt ctttgcaaag gcaaatccaa tcgttccaac
      421 tccacaataa gcgtcaatca aatggtcttc tttatcaaca tccagcgctt ttactgcttc
      481 gctatagagg acttctgttt gctcaggatt tagttgataa aaagctcgag gggatagtga
      541 aaattcataa ttgagtacac cttcttgaat actctcttgc ccccagataa tctctgtctt
      601 ttcaccatat atctcactgg ttttagctgt atttgtatta acagctactg tcacaacttc
      661 tgggaaatct ttaaccaact cttttaccaa ttgagttaaa ttaagctggc ggtttgtaac
      721 aataataatc tgaacctgtc cggtctttct cgcgcgtcgg accataatag tacggacacc
      781 tagaactttt ctctcatccg tgattggaat ctggtgataa gtaagtaatt ctgctaagcg
      841 attagcaatc acttgggttt ccttatcttg taccaggcag tctttcaact ctactaaata
      901 gtgagagttt tgtgcatata agcccgcctt gacctgattt ttaaattttc gagtctgaaa
      961 ttgtaactta gctctgtaat attttggttc ctgcattcca atagttggac gaatttcata
     1021 attttcatat cctgcaggag caaatttttt cagcgcttga tgaagtaagt ccgtcttgaa
     1081 ctccagctgc ttatcataat gcaggtgcat gatttggcag cctccgcatt cattataaat
     1141 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
     1201 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
     1261 aggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
     1321 cttgattttt aatggtattt tttgtttcac tttcagattc atacccctat cttatcacat
     1381 tttgagttat aatagagcta tgaaaatcac aaaacttgaa aagaaaaaaa gactctatct
     1441 gatggagctt gataatggcg acaaatgcta tatcaccgaa gatacaattg ttcgttttat
     1501 gttatcgaga gataaggtga taagcgaaga ggaattgaaa gagattcaag actttgctca
     1561 attttcttat ggtaagaatc tggccctcta ccacttatcc tttaaagcac gcactgaaaa
     1621 agaagtcaga gaatatctga aaaaatacga tattgataaa aacatcgttt ctcaagttat
     1681 tgctaatctt aaagaagata agtggattaa tgatggtcag tacgcttatg ctatcatcaa
     1741 tgccaatcaa gtttcaggag acaagggacc ttatgtactg actcagaaat tagcacaaaa
     1801 aggaatttca aaatctacta tagaagaaat cttgaatgat tttgattttt cggaagttgc
     1861 tcaacgtgta gccaataaac tattgaaaaa atatgaggga aaacttccag ctcgtgccct
     1921 gcaagataag attatccaga acttgactaa caagggcttc tcttattttg atgctaaaat
     1981 tgcctttgac gaattggata gtcaagttga ccaagaaacg actcaggaac tcatcttcaa
     2041 ggaacttgat aagcaatata ctaagtatgc ccgaaagtat gaaggatacg aactgaagca
     2101 gcgtttaact caagttttag cacgaaaggg ctacgatttt tcggatatag caagcgctct
     2161 tagagaatat ctttaatatt tccaagtgaa attcacagat tttaggtaat tttatggtac
     2221 aatagtaaat gataaactta taaattgtag aaagttggtt agttatgaag cttccaaaag
     2281 aaggcgactt tattacaatt caaagttata agcatgatgg gagtctccac cgaacttggc
     2341 gggacaccat ggtactaaaa acaacagaaa acgccattat tggtgtcaac gatcatacac
     2401 ttgttaccga aagtgatggt cgtcgttggg tcactcgaga accggctatt gtttactttc
     2461 acaagaaata ttggtttaat atcattgcca tgattcgtga taatggaact tcttactatt
     2521 gcaatatggc tagcccctac tatctggatg aagaagcact gaagtatatt gattacgatt
     2581 tggatgttaa aatttttaca gatggggaaa aacgtctctt ggacgttgaa gaatacgagc
     2641 gtcacaaacg caaaatgaat tattctgatg acttggacta tattttaaaa gaacatgtca
     2701 aaattcttgt tgattggatt aacaatggac gtggtccttt ctcagaagcc tatgtaaaca
     2761 tttggtacaa gcgctatgta gaactaaaga atcggtaaag ttgtcaaagg tcaggaacaa
     2821 aatcctgacc ttgtttt
//
LOCUS       DAVIME010000090         2696 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVIME010000090 DAVIME010000000
VERSION     DAVIME010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2696
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.090"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..2592
                     /gene="lanM"
                     /locus_tag="VV588_002083"
     CDS             <1..2592
                     /gene="lanM"
                     /locus_tag="VV588_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU7084344.1"
                     /translation="KEYEWIDKNGNIFSSLVFYLEDLIYPWIVKPLVLEINSLREKGL
                     LEGESEQQRYKYFITLFDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLEND
                     FSVLEEELGLRGKLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIA
                     EYIRKVDEKIRIRIPRTIAYSDHSYEEFIDYLPLEQKKKLPEYYYNFGVLLAFIYLFN
                     GSDIHFENLISYGDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVK
                     REDGLDVEMSALTGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEF
                     DKYIKDFKKGFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLY
                     HPDFYEEMLDREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFG
                     NHFISLHQFSGYDYFMKYLPNNNLENLEKQLDIIEIYFPSFDQRKKGYKLNLSNRKKL
                     PNESLVTILHNEVENIADSLVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAG
                     ILLFMYYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYD
                     TNTLACLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRL
                     VLSLGDTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPRE
                     KIKIHSLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTS
                     MELESLLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIV
                     IPSLLEI"
BASE COUNT          968 a          314 c          486 g          928 t
ORIGIN      
        1 aaagaatacg agtggattga caagaatgga aatatttttt cctctctagt attttattta
       61 gaagatttaa tctatccttg gattgttaaa cctttggttt tagagataaa ttcattgcgt
      121 gaaaaaggtt tacttgaagg ggaatcggag cagcaacggt acaaatattt tataacattg
      181 tttgacaagg aagagaatat attaaatttt tataacaaat atcccgtttt actgaggcaa
      241 atatcggagt cttgtcttcg gttctatact tattttatag aaattttatc aaatttagaa
      301 aatgatttta gtgtgctaga agaagaatta gggctaaggg ggaaattaaa tgatataaaa
      361 tttggaaagg gtgatacaca cagccaagga aaaactgttt tgatactctt ctttgatgac
      421 gcgaaaattg tttacaagcc taaaaattta ataatcaata actcactaaa tactattgct
      481 gagtatatcc gaaaggttga tgaaaaaatt aggataagaa tacctcgaac tattgcttat
      541 tcggatcaca gctatgaaga atttattgat tatctacctc tagagcaaaa gaaaaaatta
      601 cctgaatatt attataattt tggtgtgctt ttagcattta tatatttatt taatgggagt
      661 gatatacatt ttgaaaattt aatttcctat ggagatatgc ctgtaataat agactttgaa
      721 acaatgttac agcaacctct atttgatgat aaaactggtc agagtttgct ggataccctg
      781 tttcacaggg tgactcgaac tttgcttctt ccaacagagg gagtaaaaag ggaggatggt
      841 cttgatgttg agatgagtgc tcttacagga aattttaaga aggatgcttt taatggtcaa
      901 gttttaatta atttaaatac tgataaggta aagtttgata ttgggaaaat tgattttgaa
      961 ggtgggaaaa acctgcctgt tcgggatggt gatatagaat ttgataagta tataaaagat
     1021 ttcaaaaaag gttttaggga tttttatctg atatttgaag agttaaataa aacagaagaa
     1081 tttaaaatgc tattaaaagc aaacttgtat ggtttaaaga caagggtact ttttagagac
     1141 acaaatagct atgcttcagt actatctttt ttatatcatc ctgattttta tgaagaaatg
     1201 ttagatagag aaaaagcatt ggaaaatctc tggagcaata agttttctaa tcaaggtatt
     1261 gtagcaagcg aatgtgaaca aatgaggtta ttagatattc cgatttttta tacagataca
     1321 aatatcaatg aaatctacga tgattttgga aatcatttta tttccctaca tcaattttct
     1381 ggatatgact attttatgaa atatttacct aataataatt tggaaaattt agaaaagcaa
     1441 cttgatatca ttgaaattta ttttccaagc tttgatcagc gaaaaaaagg atataaatta
     1501 aacttatcta atagaaaaaa actcccaaat gaaagtttag ttactattct gcataatgaa
     1561 gtagaaaata ttgcagactc tttggttatt aataatattt atgacgaata tccaatttgg
     1621 agtatacctg ttaattttaa aggttctaaa tggtgtcttg aacaaacggg taatgatatg
     1681 tataggggta gagctggaat attactgttt atgtactatg taaaattatt gaaagataaa
     1741 tcatcatata ctcaactgta caataaaatg ttatctgcaa ttccgccatc tgtttcttta
     1801 tctaagacca catttggttt aactggggat ataggatatt tcattgttct atccattata
     1861 gaggattacg atacaaatac tctcgcatgc ttaaattata taaagagtgt tttaactgag
     1921 cttgaaaaga ctgattttgc aagtgtttca aacaagtctg actatattaa tggtcttcta
     1981 cctttaatta atacactggt aagatattat aggagaggaa tagagaagga acgtgttcta
     2041 aggctagtat taagtttagg tgatacgcta tataatgatg taagcgagag agataatagt
     2101 aattttggat atagttttgg ccatggacta tcaggtgtaa tttttacatt aaaaaatatt
     2161 tataaagtga caagacttaa aaaatataaa gaattaattt tacaactagt tcctagggag
     2221 aaaatcaaaa ttcattcttt gaagtggtgt agtggagaat ttgggacatt agttaatcat
     2281 ccccaaagtg ttccagaggg aattgtagct agtttagata atgatacatt ttgccatgga
     2341 agtatggcca taataaattt ttacatcgac tacatgaaag aaatggatac tagtatggaa
     2401 ttggagtctt tattgtgtag tgttgtaatg aataaatcaa aagaaggaga gtatcgtatc
     2461 gtccaaacaa gcaatttccc agatttttct ttgtatacag gtgtgactgg tattgcttat
     2521 acttttttaa ggtatatcgc actgaatcag aatgacaaaa agatagttat cccctcatta
     2581 cttgaaatct agcttaattt atagttttgt ttctaaaata gaggtgtcca ctcattaagc
     2641 aatataaaaa taccaagatt gactagttta atatgtaatt ctataaaata ttttta
//
LOCUS       DAVIME010000091         2563 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVIME010000091 DAVIME010000000
VERSION     DAVIME010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2563
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.091"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            125..601
                     /locus_tag="VV588_002084"
     CDS             125..601
                     /locus_tag="VV588_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU7084345.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAETTA"
     gene            639..944
                     /locus_tag="VV588_002085"
     CDS             639..944
                     /locus_tag="VV588_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU7084346.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            992..2467
                     /locus_tag="VV588_002086"
     CDS             992..2467
                     /locus_tag="VV588_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU7084347.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          788 a          487 c          502 g          786 t
ORIGIN      
        1 tataacaaac tataaacaaa aaaaaatata aaaaaagaga caaaaaagaa cagaaagtaa
       61 ttgacaacgg tttcatatag tgttatactt atggcataaa gttaatggaa agaagggaaa
      121 acttatggta ttagattatt tctttgacaa aaaccttgtg ttttgcttag aagcggataa
      181 tcaagaacaa ctctttgatc aggttgcaac tttattggaa gaacgagaaa ttgtcactcc
      241 aacttatcgt gaagccttga tcacgcgtga aaagtcattt ccaactggtt tagatatgga
      301 atttctagga aaggacttgc caaatgtagc gattcctcat acagatattg ttcataatct
      361 agctgagaaa gtggtggttg ttcgattaga aaaaccagta acttttcaca atatgatagc
      421 tcctgataag gaagtagaag tatccttgct cttctttatc atcaataact caagttcaag
      481 tcaaacaaat attctggctc agttgatgga ctttttcaca ggaaatggac atcttgaaga
      541 cctatcaaaa atttccgaac cagaaaaact ttatgcttac attgctgaaa caaccgctta
      601 atcttgtcta ttaaaaaata aaatcggagg aaatctaaat gattaaaatt cttgctgcct
      661 gcggtgcagg tgttaactca agtcaccaaa ttaaaagtgc tctagaagaa gaactttcaa
      721 accgtggtta tgatgttcac tgtgatgcag tcatggtgaa agatgtaaac gaagacctta
      781 tgaaaggtta cgatatcttt acaccaatcg ctgcaacaga ccttggtttt gaaccaggta
      841 tcccagttat cgaagctgga ccaatcttat tccgtatccc agcaatgagc gctccagtat
      901 ttgacaatat tgaagcagct attaaagaac atggattaag ctaattctaa tttgttaaca
      961 ttcatataac ataaaaaagg gaggaactgt tatggatgca atctttgacc taatcggaaa
     1021 ggttttcaat cccatcttag aaatgggtgg acctgtcatc atgttgatca ttttgacagt
     1081 attggcttta ctttttggag tgaaattctc caaagcgctt gaaggtggta tcaaacttgc
     1141 catcgctctt acaggtatcg gtgctatcat cggtatgcta aatggtgctt tctcagcatc
     1201 acttgcaaaa ttcgttgaaa acactggtat ccaattgagt attacagacg ttggttgggc
     1261 accactcgca acaatcactt ggggttctgc ttggacacta tacttcttgc tcatcatgtt
     1321 gattgtcaac gtagtgatgc ttgctatgaa gaaaaccgat acacttgatg tcgatatctt
     1381 tgatatctgg cacttgtcta tcacaggtct cttgattaaa tggtatgctg ataacaatgg
     1441 tgtgagtcaa ggggtttcac tctttattgc tacagcagct atcgtccttg tcggtgtgtt
     1501 gaaaattatc aactctgact tgatgaaacc tacatttgat gaccttctta acgccccaag
     1561 ttcatcacca atgacatcaa ctcacatgaa ctacatgatg aacccagtta tcatggtttt
     1621 ggataagatt tttgaaaaat tcttcccagg ccttgataaa tatgactttg atgctgctaa
     1681 attgaacaag aaaatcggtt tctggggatc taaattcttc atcggtttca tccttggtat
     1741 cgttatcggt attatgggaa ctccacatcc aattgcaggt gttgcagatg cagataaatg
     1801 gcgtcttgtt atcaaaggat ggttgtctct tggtttgact gccggtgtat ctttggaact
     1861 cttctcactt atcggttcat ggttcatcgc agccgtagaa ccactatcac aaggtattac
     1921 aaacgttgct actaaacgtc ttcaaggacg taaattcaat atcggtcttg actggccatt
     1981 catcgctggt cgtgctgaaa tctgggcttg tgccaacgta cttgcaccaa tcatgttgat
     2041 tgaagcagtg cttctttcaa aagttggaaa tggtatcttg ccacttgcag gtatcatcgc
     2101 tatgggtgtt actccagctc tcttggttgt aactcgtggt aaattgctcc gtatgattat
     2161 cttcggaaca ctcttgttgc cactcttcct tctttcaggt acacttattg caccatttgc
     2221 aacagaactt gctaaaggtg taggtgcctt cccagaaggt gtgagccaaa ctcaattgat
     2281 tactcactct actcttgaag gaccaatcga aaaacttctt ggttggacaa ttggtaacac
     2341 tacaactggt gatatcaaag caatccttgg tgcagtagtc ttccttgtat tctatatcgg
     2401 tatctttgct tggtacagaa aacaaatgat caaacgtaac gaagagtacg cagcaaaagc
     2461 aaaataatgc gctcctataa aatataaact taatgaaaat caaagagcaa actaggaagc
     2521 tagccgcagg ttgctcaaaa cacagttttg aggttgtaga taa
//
LOCUS       DAVIME010000092         2532 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVIME010000092 DAVIME010000000
VERSION     DAVIME010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.092"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..559
                     /locus_tag="VV588_002087"
     CDS             <1..559
                     /locus_tag="VV588_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU7084348.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VV588_002088"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VV588_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU7084349.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2032
                     /locus_tag="VV588_002089"
     CDS             1424..2032
                     /locus_tag="VV588_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU7084350.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPKAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(1980..>2532)
                     /locus_tag="VV588_002090"
     CDS             complement(1980..>2532)
                     /locus_tag="VV588_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU7084351.1"
                     /translation="NIPMNWVVIKIKDIFSINTGLSYKKGDLSINKGVRIIRGGNIKP
                     LEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGF
                     IFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAP
                     FEEQELITQKVEKLFEKVNQLWK"
BASE COUNT          890 a          379 c          423 g          840 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggagtgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcgggag ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttaga
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaacaaa gacgaaacaa cctcttatcc
     1501 tatatatgaa atcccaaaag catggagata tattaaattt gctagcctag ttaacttcag
     1561 aataggaaaa actcctccac gcagtgaagc tactttttgg ggaactgaaa taccctgggt
     1621 atctatatca gatatgccta tatctggtta tgtaactaat acgagagaat ctatttctaa
     1681 attagcatta aaatcaaaga aaatagacat ttcacctaaa ggaactttat taatgagttt
     1741 taaattatct attggaaaag ttgccatatt ggatattcct gccactcata atgaagccat
     1801 tatatcgata ttcccctatg ctaataaaga aaatattatc agagattact taatgatatt
     1861 tttgccactt atctctactt taggtgattc aaaagatgct atcaaaggga aaacattaaa
     1921 tagtaccagt atctccgaat tattaatccc tatttctaat catgaagaga tgaaaagaat
     1981 catttccaaa gttgatttac tttttcaaaa agtttctcaa ctttttgagt aataagttcc
     2041 tgttcctcaa aaggagctaa cggaattaat agctcgctta gtgtagtttt aggaatatta
     2101 tataaagctt gacctgatag tttagttatt gctttcaatt gtttataaaa taacggagag
     2161 gacaagttaa ataatagaaa ttttgaaata atctctgaac tttcgaatgg tgttaattgg
     2221 aaaataaatc caccagccac aacaccatca tagtctttat cgattcttgc aaactttcca
     2281 atatgttcta aagaggttga tacaggtgtt attagctgat tatgttttaa ataaacttgc
     2341 tcagaggaga tgaattgtgt gtcaatgtag taatcattat ccaacagaga aaattctaaa
     2401 ggcttaatat taccaccacg tataattcta acacctttat taatgcttaa atcgcccttc
     2461 ttgtaagaaa gacctgtatt tattgaaaaa atatctttta tttttataac aacccaattc
     2521 ataggtatat tc
//
LOCUS       DAVIME010000093         2043 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVIME010000093 DAVIME010000000
VERSION     DAVIME010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.093"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            37..1062
                     /locus_tag="VV588_002091"
     CDS             37..1062
                     /locus_tag="VV588_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU7084352.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1052..>2043
                     /locus_tag="VV588_002092"
     CDS             1052..>2043
                     /locus_tag="VV588_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU7084353.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKN"
BASE COUNT          717 a          289 c          365 g          672 t
ORIGIN      
        1 gatacaatag acttgaaata tgtttaagga gtttttatga aaaacaaatt ttttctaata
       61 gctattttag ctatgtgtat agtttttagc gcttgttctt ctaattctgt taaaaatgaa
      121 gaaaatactt ctaaagagca tgcgcctgat aaaatagttt tagatcatgc tttcggtcaa
      181 actatattag ataaaaaacc tgaaagagtt gcaactattg cttggggaaa tcatgatgta
      241 gcattagctt taggaatagt tcctgttgga ttttcaaaag caaattacgg tgtaagtgct
      301 gataaaggag ttttaccatg gacagaagaa aaaatcaaag aactaaatgg taaagctaac
      361 ctatttgacg atttggatgg acttaacttt gaagcaatat caaattctaa accagatgtt
      421 atcttagcag gttattctgg tataactaaa gaagattatg acactctatc aaaaattgct
      481 cctgtagcag catacaaatc taaaccttgg caaactttat ggagagatat gattaaaatt
      541 gattcaaaag ccttaggtat ggaaaaagaa ggtgatgagt taatcaaaaa tactgaagct
      601 cgtatatcca aagaattaga aaaacatcca gaaatcaaag gaaaaatcaa aggaaaaaaa
      661 gtattattta ctatgattaa tgctgcagat acatcaaaat tctggattta tactagcaaa
      721 gatccaagag caaattattt aacagattta ggtctagttt tccctgaatc attaaaagaa
      781 tttgagagtg aagatagttt tgcaaaggaa atttctgcag aagaagcaaa taagataaat
      841 gatgctgatg taatcataac ttatggtgat gataaaactc ttgaagcttt acaaaaagat
      901 cctcttttag gtaaaataaa tgcaattaaa aatggtgccg ttgctgtaat tccagataat
      961 acaccgttag cagcctcatg cactccaaca ccactttcaa taaactatac tattgaagaa
     1021 tatctaaatc ttttaggaaa tgcatgcaaa aatgcgaaat aaaaaacaaa taaacctagg
     1081 cataattttt gtaatctgcc taggtcttct tattacaata tttttgtcat taaagcttgg
     1141 aacaaaagaa attaatatca gagatttttt agcagctttt ggaatgggta atacaaatga
     1201 tgattttatt aaatcaatta tatataaaag aatacctaga actatttttg caattttagc
     1261 aggttctagt cttgccataa gcggtgtatt gatgcaatca gttactagaa acccaatagc
     1321 tgatccaggt atactcggta taaacacagg agcaagtctt agtgtagtaa ttggtctttc
     1381 ttttttagga atttcatcaa gcataagcca tataagtttt gcaatcattg gtggcttagt
     1441 aagtgcaatt tttgtatacg cgattgctgt aagcggaaaa gcaggcctta cccctataaa
     1501 acttgcctta tcaggaactt gtgttagtat ggctttaagc agttttgtaa gttttttaat
     1561 tttaccgaat aataacgtct tagacaaatt tagattttgg caaataggta gccttggagc
     1621 agctacatta tcttctatat ctacactact accttttata attttaggtc acttgatagc
     1681 tatatttatt tcatcagatt taaacgcttt agctatgggt gatgaaatgg ctgttggtct
     1741 tggagttaat gttaatagga taagatcact tgcaataatt gcaagtgtgc ttttatgttc
     1801 aagtattact gcaattggtg gacctattgg cttcgtaggt cttatagttc ctcacttttg
     1861 tggcttattt ataagcaaag atatacgcac aatgaccatt tcttcatctt ttataggtgc
     1921 agagctcttg cttatatgtg atataatcgg ccgtatgtta ggtaaaccag gtgaaattga
     1981 agtagggata attactgcaa taatcggggg tccagtactt atttatgtaa ctatgaaaaa
     2041 tag
//
LOCUS       DAVIME010000094         1733 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVIME010000094 DAVIME010000000
VERSION     DAVIME010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.094"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            77..484
                     /locus_tag="VV588_002093"
     CDS             77..484
                     /locus_tag="VV588_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU7084354.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQTDEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            649..948
                     /locus_tag="VV588_002094"
     CDS             649..948
                     /locus_tag="VV588_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU7084355.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="VV588_002095"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="VV588_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU7084356.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          577 a          335 c          309 g          512 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactctc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca aactgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaacttgta aaaagtcaac tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aaggcctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactaag cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg gaggaaaggt
     1201 attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtagcaaga
     1261 tagatatgag gcagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaagaccgc tttaaagccc
     1381 tttactggga tggtcaagga ttttggctac tatataaacg ctttgagaac ggcagactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcacacc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacctct
     1561 gcttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttcttgt
     1621 ttcattttac tatagaacga tttgaaggcg tttataatat ttagctgtac gagagtcttt
     1681 aaaagtgttt tgatggtttg gatttcttct ttagttgatt tcatatcact att
//
LOCUS       DAVIME010000095         1595 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVIME010000095 DAVIME010000000
VERSION     DAVIME010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.095"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            195..899
                     /locus_tag="VV588_002096"
     CDS             195..899
                     /locus_tag="VV588_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU7084357.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            880..>1595
                     /locus_tag="VV588_002097"
     CDS             880..>1595
                     /locus_tag="VV588_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEU7084358.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQE"
BASE COUNT          567 a          192 c          274 g          562 t
ORIGIN      
        1 taattgctaa acggcttgag gtatatgcta ctgttataga aatgatttta aactaaaatc
       61 aaaattactc caaaaatagt attgattttg gtttaataca aaacatatgt aataatgtga
      121 gtcaacaaaa gtctgttttt gtaccatact atcttgaaaa atctactaaa ttcaaattga
      181 gaggatgaat taaaatgaat aaaatattta tatatgcagg agtgcgaaat cataactcta
      241 agactttaga gtatactaag agactttcaa gtatcatttc tagtagaaat aatgttgata
      301 tatctttcag gacacctttc aattcagagc tagaaatatc taattctgat tcagaagagt
      361 tgtttaagaa aggaattgat aggcaaagta atgctgatga tggaggtgtt ataaaaaaag
      421 agttattaga gtctgatatt ataattatct cttctcctgt atatttacaa aacgtatctg
      481 tggacacaaa aaactttatt gaaaggattg gggggtggag ccatcttttt cgattagctg
      541 gaaagtttgt tgtaacatta gatgttgctg agagtaacgg ctctgataat gtgtcagaat
      601 atcttagaga tatattttca tatatgggag gacagatatt acaccaagtt tcaattacca
      661 attcactcaa agatattgca gaggctcagt tgatggaggc aacttataaa attgaagatg
      721 tacttgaagg gaaaattaag tacaaaacaa cggattatca agaaagagct taccagacat
      781 taaaattaat tttagaaaat tatgattccg aacattttga gaagatgtat tgggagaaaa
      841 aacgcctttt tgaagctaat agtttagagg aatggtatta tgttgaaaat attaaataac
      901 tctgtcatat atttatgttt gattccgtta ttgttcctat tattgataat ttttccaaat
      961 gattcattaa tctattattt tcgattgatt ttaatttcgt taatatcaat tacattacat
     1021 gaactaggtc attttttagt gggaagatgt ttatcttata aactagagat gcttgctact
     1081 ccctttttct tctatttcag aaaaaaaata tatttcaaat ttccagtgtt attagcattc
     1141 ggttattgtc aaatgagtaa tagaaacatt actaatgaaa aaaatagtga taggaatttg
     1201 gtgttctact tctttggggg aggtggagct aacctaattg tcgcaatatt agcacttttg
     1261 ggatttgtgc cgtacgcatc agaatttttt attttgaata taattctttt tctagttacg
     1321 gtatgtttac caattgatgg aacagatggc aatgctatta gagagatagt tttgtattca
     1381 aaagattcaa aaacatatca gagattcttt gcgaacagtc tctataataa tccttatata
     1441 acaatcgacg attttgcaaa attaacctct aaagaaaaat cttttttttc aaaatttgaa
     1501 aaatgtttga taaaccttta ctttgaagtg aaaggtgaag ggtcagcatt tacaattgct
     1561 aatcatgaag tttttgattc aaatattcag gaaaa
//
LOCUS       DAVIME010000096         1472 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVIME010000096 DAVIME010000000
VERSION     DAVIME010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1472
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.096"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..334)
                     /locus_tag="VV588_002098"
     CDS             complement(<1..334)
                     /locus_tag="VV588_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU7084359.1"
                     /translation="MQNHYTTKGEHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVM"
     gene            complement(792..1190)
                     /locus_tag="VV588_002099"
     CDS             complement(792..1190)
                     /locus_tag="VV588_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU7084360.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFYLQDYLYIRQRYYYQKNL"
     gene            1318..1395
                     /locus_tag="VV588_002100"
                     /pseudo
     CDS             1318..1395
                     /locus_tag="VV588_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT          430 a          286 c          244 g          512 t
ORIGIN      
        1 ccatcaccat catttcaggc gaaaattttt ggttatgata gtggagaatc ttttccttta
       61 gttccttggt caagcttgat ttcttgaccg agcgcttgcg attgttttca taagactgtt
      121 gagcatagtc ggcagaataa acctctttga agcgcccttt tccaagacat tgtcggactg
      181 tcccacgctt gatttcagtg tggatagttt gaggaacttt tccaagcaga gaggcaattt
      241 ctctatttga tttcccttct tttttccatc tttcgattaa gcgacggcta tcgattgtca
      301 aatgttcgcc ttttgtagta taatggtttt gcatctctgt gcctttcttg tgtttgtggt
      361 tgaacaacaa gtataacaca gaggtgtttt cttatgccta caagagcttt cattatttcc
      421 attttctttc ggatttcact ctattctgaa aaacttgtgt atatttactg aagctagcaa
      481 gtcttacctg taaatttaat gaaagcaaca caaaatccga gaggggaatc tcggattaat
      541 gtcaatttaa aaagatagag agtttttagt ttaaataaat tgttttaaaa tatcaacaac
      601 atcacttctt ttcttaacct gataagcctt gattcctaat tttggagcta cgattatatt
      661 gtcctcaata tcgtctagaa agacacaatt tctaggttat aactggtatt tatcgatagt
      721 tactcatata catcagtcca cctccatact tatgtgcgag cctctctttg tattatacct
      781 ccatactcac cttacagatt cttttggtaa taatatcttt gcctaatgta gagatagtct
      841 tgcaaataaa aaacttcctt gtagccatgt ttctgataaa agtccggtgc ctggaactga
      901 taagtattga caaaggcaaa acaacaattt cgattcttag cttcactttc tgcctgttgc
      961 aatagttttg aaccgattcc ttgccctcgc agttcctctt ttacaaacaa atactcgatt
     1021 tctagccaat ttccaaaagt ctctgctatc aaacccgcaa ggagattgcc cttttcatct
     1081 tcgacataaa gattaagtgg ctcactttca gcctcttccc tttttgaacg gttataaaca
     1141 cgaatcagat tccctatttc ttgcgattta tgtgattcct tattttccaa tctaaagtat
     1201 aatgaaatga aataaaacat gcgcaaatcg attaaggaat ttaatctaat ttctaataat
     1261 gtcttagaaa tcaaagttta ctattttaac ttcaatgcac tatacatcta atactcaatg
     1321 aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaaacactg ttttgaggtt
     1381 gtagatagaa ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac
     1441 gaagtcagct caaaacatgg ttttgaggtt gt
//
LOCUS       DAVIME010000097         1391 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVIME010000097 DAVIME010000000
VERSION     DAVIME010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1391
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.097"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..409
                     /locus_tag="VV588_002101"
     CDS             <1..409
                     /locus_tag="VV588_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU7084361.1"
                     /translation="DEVDRTPAENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWN
                     QLGELYQWFTDTYAHLSLQELKAKLNENINSISAMIDSLSEEELFEPHMRKWADEATK
                     TATWEVYKFIHVNTVAPFGTFRTKIRKWKKIVL"
     gene            518..1164
                     /locus_tag="VV588_002102"
                     /pseudo
     CDS             518..1164
                     /locus_tag="VV588_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(1153..>1391)
                     /locus_tag="VV588_002103"
     CDS             complement(1153..>1391)
                     /locus_tag="VV588_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU7084362.1"
                     /translation="MKIYPQVQTPRKSSKLKPLTAEDKACNHALSKERSKIENIFAKV
                     KTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT          506 a          189 c          276 g          420 t
ORIGIN      
        1 tgatgaagtt gacagaactc cagcagaaaa ccttgcttat caggttggtt ggaccaactt
       61 ggttcttaaa tgggaagaag atgaaagaaa ggggcttcaa gtaaaaacac catcggataa
      121 atttaaatgg aatcaacttg gtgaattata tcagtggttc acagatacct acgctcattt
      181 atctctgcaa gagttgaaag caaaattaaa tgaaaatatt aattctatct ctgcaatgat
      241 tgattcgttg agtgaggaag aattatttga accgcatatg agaaagtggg ctgatgaagc
      301 gactaaaaca gcgacttggg aagtgtataa gtttattcat gtaaatacgg ttgcaccttt
      361 tggaactttc agaactaaaa tcagaaaatg gaagaagata gtattataaa ttatattttt
      421 aactttaaaa aatttcataa aaatggttac caaaggcgat agaagaaaaa ctatcgtctt
      481 tttctttgca aatttttaag aagggaggtg atcttgcatg gactttgaat atttttataa
      541 cagagaagcg gaaagattta acttcttaaa agtaccggag atattagttg atagagaaga
      601 atttcggggc ttatcagcag aagcaattat cctttattcc atacttctta aacagacagg
      661 aatgtcattt aagaataact ggatagacaa ggaaggcaga gtatttatct attttactgt
      721 cgaagaaatt atgaaaagaa gaaatatctc aaagccaact gccataaaaa cattagatga
      781 gcttgatgta aaaaaggaat aggactgatc gaaagagtaa ggcttggact tggtaagccg
      841 aacatcattt atgttaaaga ctttatgagt atatttcagg taaaagaaaa tgacttacag
      901 aagtcaaaaa acttaacttc agaagtaaaa gattttaacc tcagaagtaa agaaaatgaa
      961 cttcaagagg ttaagaacct tgactctaac tatatagaga ataataagag taagtatagt
     1021 aagagagaat atagttttgg tgaaaacgga cttggaacat ttcaaaatgt gtttttagct
     1081 gctgaagata tatcggattt acaaatcata atgaactcac agcttgagaa ttacattaga
     1141 cttcctgcaa aactagaatc ctagttcatg attgataatg ccagcaatca aattcattcg
     1201 taatccgaag cgtttacgat gatttcgata gattgttgaa aacattttaa acgtttttac
     1261 tttggcaaag atgttctcaa tcttgcttct ctccttggat agcgcatggt tacaggcttt
     1321 atcttcagct gttagcggct tgagtttgct ggatttacgt ggagtttgta cttgaggata
     1381 tatcttcatg a
//
LOCUS       DAVIME010000098         1259 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVIME010000098 DAVIME010000000
VERSION     DAVIME010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1259
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.098"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            10..>1259
                     /locus_tag="VV588_002104"
     CDS             10..>1259
                     /locus_tag="VV588_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU7084363.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRIHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     IEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTKFVLS"
BASE COUNT          425 a          267 c          190 g          377 t
ORIGIN      
        1 aagaatcata tggaacaatt acattttatc acaaaattac tagacattaa agaccctaat
       61 atccagattt tagacatcat caataaagat acacacaagg aaatcatcgc caaactggac
      121 tacgacgccc catcttgccc tgagtgcgga agtcaaatga agaaatatga ctttcaaaaa
      181 ccttctaaaa ttccttatct tgaaacaact ggtatgcctt ctagaattct ccttagaaaa
      241 cgccgtttca agtgctatca ctgttcaaaa atgatggttg ctgagactcc cctggtaaag
      301 aaaaatcacc aaatccctcg tatcatcaac caaaaaattg ctcaaaagtt aattgaaaaa
      361 atttctatga ctgatattgc ccatcagctg gccatttcaa cttcaactgt cattcgcaag
      421 ctcaatgact ttcactttga gcatgatttt tctcggcttc caaagattat gtcttgggat
      481 gagtatgcct tcactaaggg aaagatgagt ttcattgcgc aagattttga taatcttaat
      541 attatcactg ttcttgaagg cagaacacaa gctgtcatcc gaaatcactt tcttcgctac
      601 gatagagccg ttcgttgtca agtgaaaatc attacgatgg atatgtttag tccttactat
      661 gacttggcta aacagctttt tccgtgtgct aaaatcgttc tagatcgttt ccatattatc
      721 caacatctca gccgtgccat gagtcgtttt cgtgttcaaa ttatgaatca gtttgaacga
      781 aaatctcatg aatacaaggc tatcaagcgt tactggaaac tcatccaaca ggatagtcgt
      841 aaactcagcg ataaacgttt ttatcgccct acttttcgca tacacttaac aaataaagaa
      901 attcttgaca agattttaag ctattcagaa gacttgaaac accactatca gatctatcaa
      961 ctcttacttt ttcactttca gaacaaagac cctgagaaat ttttcggact cattgaggac
     1021 aatctgaagc aggttcatcc tatttttcag actgtcttta aaacctttct aaagaacaaa
     1081 gaaaaaatcg tcaatgctct tcaattacct tattccaatg caaaattgga agcgaccaat
     1141 aatctcatca aacttatcaa acgaaacgcc tttggatttc ggaactttga aaacttcaaa
     1201 aaaaggattt ttatcgctct gaacatcaaa aaagaaagga cgaaatttgt cctttctca
//
LOCUS       DAVIME010000099         1145 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVIME010000099 DAVIME010000000
VERSION     DAVIME010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.099"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..283)
                     /locus_tag="VV588_002105"
     CDS             complement(<1..283)
                     /locus_tag="VV588_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEU7084364.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPI"
     gene            449..619
                     /locus_tag="VV588_002106"
                     /pseudo
     CDS             449..619
                     /locus_tag="VV588_002106"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            608..>1145
                     /locus_tag="VV588_002107"
     CDS             608..>1145
                     /locus_tag="VV588_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU7084365.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRL"
BASE COUNT          448 a          128 c          195 g          374 t
ORIGIN      
        1 atataggtaa tggtatgtag ggtaggaaga acaaactgaa taataagatt aaaattggta
       61 aattagatat taatgctgct cctaaatttt tccaataatc tttaaaaaaa ctgtttgcga
      121 agtctctata gggataggat tcctcgtgtc gtacaatttt tattagagtt gctattaggg
      181 cactttcacc tgatccgata gcaataactg ttactactga cgctacatag agtagattta
      241 acattataag atttgaaact ttatcaataa attttatctg catctttaac tcctgctgtt
      301 tttatactta taatatcaca tcatttgagt ttcatcaact ttgaatacat taagaaagaa
      361 tataactatg aggaaaggaa aaaattatta tgaataaatc caaaaaatat aaagaaagaa
      421 ttcattatga atacgataat cttactaaat cagagaaaaa attgctgact atattttagt
      481 tagagatagt gaaatagttt atgaaacgtc ttcagaaatt gttagtaaag taaaagttgg
      541 agagggaact cttaatcgat tttgcaaaaa gattggatac tctggttttc aggaactaaa
      601 attaaaaatg acgaaagata tattagagtt agaatctcaa aaaatgagta gtgacacatt
      661 tattgatgaa ataaaaaata attatttatc tattgtggaa agtacaagaa aattaattga
      721 tggtagacaa atagaattag ctataaaatt aataagagaa gcaaaccaga ttttaatgat
      781 tggtgtgggt tctagtggaa atgcggctag agaatttgag agtagtttgt taagaattgg
      841 aataataagt aagacggtaa ttgataccca ttttcaactc atgcatactg cgttattgaa
      901 agataatgat ttgataatag cgtttagttt atctggttcc acaaaagaag ttgaggaaac
      961 tttattaaac gcaaaaagaa aaaatgttaa aattatttca ataacaaatt attcgtccag
     1021 aaatatagca aaattatctg actgcgttct tttgacatca aaaaaagaat cttatttaga
     1081 gggtggtagt ttaatggcta aggcttctca actattcata attgatgtaa tatgcactag
     1141 actct
//
LOCUS       DAVIME010000100         1120 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVIME010000100 DAVIME010000000
VERSION     DAVIME010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1120
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.100"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(1..491)
                     /locus_tag="VV588_002108"
                     /pseudo
     CDS             complement(1..491)
                     /locus_tag="VV588_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            979..1098
                     /locus_tag="VV588_002109"
     CDS             979..1098
                     /locus_tag="VV588_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU7084366.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT          382 a          175 c          167 g          396 t
ORIGIN      
        1 gggagagcaa ttaataatag attaaaatta taatcattga ttgcaggata acttgttcca
       61 gtagatttat tattaacacg attgataaaa ttatctgata ataaataata tttcaaatat
      121 gtttcgttaa gtaaagtatc caaaacaata aatgctgtac tagctatcaa atactcttta
      181 agttctctaa ctacagcaat attttttaga tatggtctaa ctgttgaaaa taagacacta
      241 ttctgcgaaa ctaattttct agcacgggaa ggcgcttgtt caggtgaaag atattgtaga
      301 tttttgtagt tgattatgtt cttttttcta tcaatactag acgtatctat atacctaaag
      361 gatttctctg gcttattttg cccaaaattc caataaattg attttatcct cacccactcc
      421 caagtatcag gaatatcata aggaacatca atttcttgag tgcttccatc agcaaacttc
      481 ccataatgtt tcttatgtgc ttcaagtata taaaaaggcg taaaaatacg cctatagata
      541 atggggttga aataggttta ttgttgatga gattgtagat aattcaattt tttacttcca
      601 atcgaatatt caaagcctcc accttttctg cctgtaattg ttcatcataa aattcaatat
      661 cttcaggatt ttccccttga caacctcggc agaaatattc ttccgctcga tcaggattca
      721 aaaatcgaca agcacaaaca aaacagtcgc catcatcatt tattgagata atatagtaga
      781 ttgaaataag atgtaaacaa atcgattagg aaagttaaat taatttctag aaatttttag
      841 cagatgtagt gtactattct agtctcaatt tactatggct tcaaatatat ctttcgaaaa
      901 aatatttaca gatgtgtaat tttgaagctt gcaaaagtta gtaaacttgt agatttcgat
      961 ttgaagtaac ttgttttctt gcccgatatt gtttttgaaa ttgaattttt ccatagtgac
     1021 tccttgattt tcttctacac gtctgatgat aaatctaatt cgcaaaagag tcaagaggat
     1081 ttttcgaaaa ataaatagcg accgaaatcg ctattttaag
//
LOCUS       DAVIME010000101          852 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVIME010000101 DAVIME010000000
VERSION     DAVIME010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.101"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            29..280
                     /locus_tag="VV588_002110"
     CDS             29..280
                     /locus_tag="VV588_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084367.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            509..811
                     /locus_tag="VV588_002111"
     CDS             509..811
                     /locus_tag="VV588_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU7084368.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYEEDFLI"
BASE COUNT          317 a           88 c          151 g          296 t
ORIGIN      
        1 aataaagtaa tagaaaagga gctatataat gagtagtcaa atgaaagctt tcttgaatga
       61 acttcaagga aatatggaag ttgttggaga attttttgat aatcctgaaa aggtaattag
      121 aaaatttgga attgtcggaa gagagaagga agcattgcta atccgtgact taaatgatat
      181 ggatgattat gctctttcaa ttcaaaatag cgttgcatcg ccttctgggg cacatagtag
      241 cacttgccat tttgttagac aagatttaca atccgcataa ttgttaatat ataaaacata
      301 aaatttcaat tttcaattag ggataataga attccttact atgatataga aagtgaatta
      361 attaggaaat cttagtcaga ggtttctgat taattcattt tttatatatt aagagtgatg
      421 tgaaatgttc aaattgtgag actactctcg gattgttgta tagaaattta aaattttatt
      481 gtgagctttt taaggaagag tggccgatat gaaaaataaa tacgatgtta aaagaattat
      541 tccggatgaa ttatcagaat cactagatat ttttctaaaa aattattctg aaactggatt
      601 gtcagattat aatacttatc tcttttatgg ttttatcttg aagtcctata aattgcctcg
      661 agaaaataga tatagcataa aattattggt gaaggaatta caaaatagag gactgaaagt
      721 tacattgatt atcaacattt attatcacgc tttaaattgt ttggctttaa atgatggtct
      781 aaaaatttat gaagaagatt tcttaatatg aattacgaaa agtatttaaa ctatttggac
      841 tatgaaactg aa
//
LOCUS       DAVIME010000102          734 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVIME010000102 DAVIME010000000
VERSION     DAVIME010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.102"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..562)
                     /locus_tag="VV588_002112"
     CDS             complement(<1..562)
                     /locus_tag="VV588_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU7084369.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDD"
BASE COUNT          261 a          116 c           91 g          266 t
ORIGIN      
        1 aatcgtcctt gaaattcgtg tcaattatgt atctattagc tataggtact aatgattgta
       61 ttacatacaa taatgctgtt acaaaaaata aaatccctag cttattccta tacttaaaaa
      121 aatactttaa aacaggcgac ttcttattat ctttacgaga cataaagcta tctaactttt
      181 taaatgttaa aatgatattt gaataatgcc tttcaaattc acttattgac attctctgcc
      241 tgccttttgc aggatctaaa atataaaact tgtttttact aattttttca agaataataa
      301 aatgagaact ctcccagaag caaatgagtg ggaaactgag cggttttaaa tctcttaccg
      361 aagctttaaa agcatgagaa cttatattaa aatctcctaa aactttactt atagatagga
      421 gagaatatcc agatctggat gatgggtaga tttcacgtag ttcatttaaa gaaatctcat
      481 atttaaaata gttcaatatc atggcacagc atgctaatcc acattctgaa ttttccattt
      541 gatatatcat tggaattttc acaatacttc ctccttgttc aaaataaagt cgataatttc
      601 ttcttgtcta aaatctacta atttctttag atacttaatc ttttctaaat atttattatt
      661 tttcgagtaa atatagtttg acaaggtaaa aacaacttct tctaaagata agttctgtgg
      721 aataatccaa tcag
//
LOCUS       DAVIME010000103          632 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVIME010000103 DAVIME010000000
VERSION     DAVIME010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.103"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..>632
                     /locus_tag="VV588_002113"
     CDS             <1..>632
                     /locus_tag="VV588_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU7084370.1"
                     /translation="YVASLKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSI
                     VYIREILSNNFIAAILDLLMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISK
                     NLIDKNIKEKVNVQNITSEVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHL
                     SIVSSITNVLQIILPVLTLIVGVNIKTFEQLTLGQIVAISTVSPYFISPI"
BASE COUNT          232 a           76 c           88 g          236 t
ORIGIN      
        1 tatgttgcat ccttaaaata tataatggat aaagagatta gctatgattt tatgaaacat
       61 ttgatatatt taccttacag tttttatgaa aaacgtactt taggggatat actttttaga
      121 gctaactcta ttgtttatat aagagaaata ctatcaaata attttatagc agctatactt
      181 gatttgttaa tgattgtggt ttatgctgtg gttttattta gcttttctaa gtacatggta
      241 atctttttaa tatcactaag tctagctcta tctattgtaa tgtatccaat cataaaaatc
      301 tcaaaaaatt taattgataa aaatataaaa gaaaaggtta atgttcaaaa tattacttcc
      361 gaagtaattt ctaaaaatag tgatattaag ctaactggag aagaggaatt ttggattaac
      421 aaatgggata attttaatac aaaacagctc atcataggtc gaaaacttga tatacattta
      481 tcaattgtta gtagtataac gaatgtttta caaattattc tccctgtttt gacccttatt
      541 gtaggtgtaa atataaaaac attcgaacaa ttgacgttag gacaaattgt agcaataagt
      601 acagtctcac catactttat ttctcctata at
//
LOCUS       DAVIME010000104          562 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVIME010000104 DAVIME010000000
VERSION     DAVIME010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..562
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.104"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            complement(<1..>562)
                     /locus_tag="VV588_002114"
     CDS             complement(<1..>562)
                     /locus_tag="VV588_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU7084371.1"
                     /translation="NTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQAGSWSHKRRV
                     CQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTDS
                     STLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLHVVGKCVRTGRKQL
                     LKLSSLYAYSELFSALYSRIRKVNLNL"
BASE COUNT          163 a          111 c          132 g          156 t
ORIGIN      
        1 aagattcagg ttgacttttc taatcctaga ataaagtgct gaaaacaatt cggaataggc
       61 atagagacta gacaatttga ggagctgctt gcgtcctgtt cgaacacatt ttcctaccac
      121 gtgaagaaaa agatggcgga agcgtttgat tgttaaagtt tggaagtcac ctccagctag
      181 atgtttgaga aaaagataga gattgtaggc gatacagctc atcatcatac gaacttcgtt
      241 tttgattaag gttgaactat ccgttttatc gccaaaaaat ccctccttca tctccttgat
      301 gaaattctcg gcttgaccac gtccacgata aagctgaaac tggtcttggc ttgttccact
      361 cgtcatattt gtaacgagag aaataacatc gtagaacaag tttccttctt ttcgttcaga
      421 gaactggcag acacgacgct tgtgcgacca agatcctgct tgatagagag tttctgagta
      481 ggcggagtgg ggcaagatgg ttaagtcctc atcctgtggg caagggaggg aaaggtctcc
      541 aagacggctc agaacagtat tt
//
LOCUS       DAVIME010000105          499 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVIME010000105 DAVIME010000000
VERSION     DAVIME010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.105"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..>499
                     /locus_tag="VV588_002115"
     CDS             <1..>499
                     /locus_tag="VV588_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU7084372.1"
                     /translation="EIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIK
                     KDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMP
                     YNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPN
                     ERPHS"
BASE COUNT          161 a          104 c          113 g          121 t
ORIGIN      
        1 atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt tatatctttg
       61 atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat atgacccata
      121 gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc caggcttatg
      181 ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga aatactgagg
      241 caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg ccacttgatc
      301 gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta atcatacctc
      361 attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt tatgaggcac
      421 ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc gaacatccaa
      481 acgaacgtcc gcattcaga
//
LOCUS       DAVIME010000106          487 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae isolate SC12-2921-P
            SAMN15562788-rid19172573.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVIME010000106 DAVIME010000000
VERSION     DAVIME010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15562788
            Sequence Read Archive: SRR12580509
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001855287.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001855287.1
            Genome Coverage       :: 110x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/19/2023 23:10:42
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,116
            CDSs (total)                      :: 2,067
            Genes (coding)                    :: 1,943
            CDSs (with protein)               :: 1,943
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 61 of 124
            Pseudo Genes (incomplete)         :: 58 of 124
            Pseudo Genes (internal stop)      :: 34 of 124
            Pseudo Genes (multiple problems)  :: 25 of 124
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15562788-rid19172573.denovo.106"
                     /serotype="22F"
                     /isolate="SC12-2921-P"
                     /isolation_source="respiratory"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Canada: Manitoba"
                     /collection_date="2012-01-23"
                     /collected_by="University of Manitoba"
     gene            <1..>487
                     /locus_tag="VV588_002116"
     CDS             <1..>487
                     /locus_tag="VV588_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU7084373.1"
                     /translation="QFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSEIIAYN
                     LSTSPNLEQVQTMLEQVFTEKHYENTILHSDQGWQYRHDSYHRFLESKGIQASMSRKG
                     NSPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYVDYYNNKRIKVKLKGLSP
                     V"
BASE COUNT          166 a           92 c           97 g          132 t
ORIGIN      
        1 gccaatttga aggctctaaa acaatggaaa agtgctacac agatgtgaca gaatttgcca
       61 ttccagcaag tactcaaaag ctttacttat caccagtttt agatggcttt aatagcgaaa
      121 ttatcgccta taatctttca acttcaccca acttagaaca agtacaaaca atgttggaac
      181 aggtattcac agagaagcac tatgagaata cgattctcca tagtgaccaa ggctggcaat
      241 accgacacga ttcttatcat cggttcctag agagtaaggg aattcaagca tctatgtcac
      301 gtaagggtaa cagcccagac aatggtatga tggagtcctt ctttgggatt ctgaaatcgg
      361 aaatgtttta cggttatgag aagtcgtttc agtcgcttaa gcaattggaa caagctattg
      421 tagactatgt tgattactac aacaataaac gaattaaggt aaaactaaaa ggacttagtc
      481 ctgtgca
//
